WO1992004867A1 - Dispositf de prelevement d'echantillons sanguins - Google Patents

Dispositf de prelevement d'echantillons sanguins Download PDF

Info

Publication number
WO1992004867A1
WO1992004867A1 PCT/SE1991/000617 SE9100617W WO9204867A1 WO 1992004867 A1 WO1992004867 A1 WO 1992004867A1 SE 9100617 W SE9100617 W SE 9100617W WO 9204867 A1 WO9204867 A1 WO 9204867A1
Authority
WO
WIPO (PCT)
Prior art keywords
sleeve
needle
sampling
intended
valve
Prior art date
Application number
PCT/SE1991/000617
Other languages
English (en)
Inventor
Anders Trell
Erik Trell
Sven Gustafsson
Original Assignee
Anders Trell
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Anders Trell filed Critical Anders Trell
Publication of WO1992004867A1 publication Critical patent/WO1992004867A1/fr

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/153Devices specially adapted for taking samples of venous or arterial blood, e.g. with syringes
    • A61B5/154Devices using pre-evacuated means
    • A61B5/1545Devices using pre-evacuated means comprising means for indicating vein or arterial entry
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/150007Details
    • A61B5/150015Source of blood
    • A61B5/15003Source of blood for venous or arterial blood
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/150007Details
    • A61B5/150206Construction or design features not otherwise provided for; manufacturing or production; packages; sterilisation of piercing element, piercing device or sampling device
    • A61B5/150221Valves

Definitions

  • the present invention relates to a blood sampling sleeve intended for coaction with a sampling tube in which a subpressure prevails and which is sealed in an airtight and liquid-tight fashion by a sealing device which is capable of being penetrated or pierced by a needle.
  • the sampling sleeve is a one-piece structure intended for one-time-use only, i.e. a so-called disposable sleeve.
  • the sleeve is also friendly to the patient, risk-free to the user and can be manipulated quickly and easily.
  • Samples are generally taken effectively by collecting blood in separate, evacuated vacuum sampling tubes which are sealed against the ingress of air and liquid by means of an appropriate sealing device, such as a rubber stopper.
  • the vacuum sampling tube is used together with a cylindrical sampling sleeve, which is open at one end thereof and provided with a throughpassing, double- pointed needle at the other end thereof.
  • the outer needle point is inserted into a patient's vein and the vacuum sampling tube then pushed into the cyl ⁇ indrical sample sleeve, so that the inner needle point will penetrate or pierce the rubber stopper fitted to the tube.
  • the subpressure prevailing in the sampling tube causes blood to flow through the open passage of the hollow needle and into the tube.
  • the subpressure in the sampling tube may also be generated by fitting a sealing plunger to the other end of the tube and by drawing the plunger out towards the opposite end of the tube, when taking a sample.
  • the sleeve is provided with a two-directional needle, wherein the inner needle is protected against contamina ⁇ tion by a displaceable seal provided at the opposite end of the sleeve, this seal accompanying the rubber stopper when moving the sampling tube axially in the sleeve.
  • the outer part of the needle is protected against con- tamination by a removeable protective cap, which is removed from the needle prior to inserting the needle into the patient's vein.
  • EP-A-0026679 A similar disposable instrument intended for veterinary use is described and illustrated in EP-A-0026679. This instrument is delivered as a complete sampling instru ⁇ ment with the needle and vacuum tube mutually assembled.
  • US-A-4,326,541 and SE-B-425943 describe different exam- pies of how valves are formed in known sampling instruments.
  • the valve taught by US-A-4,326,541 func- tions to close the connection or passageway between the outer and the inner needle when the valve is in its normal, closed position, and opens the passageway from the patient to the sampling tube in response to exter- nal, manual activation.
  • SE-B-425943 teaches an automa ⁇ tic non-return valve, which is disposed between the outer and the inner needle, and a resilient and self- sealing protective sleeve which surrounds the inner needle.
  • the protective sleeve is pierced by the needle when the sampling tube is pushed into the sleeve, and springs back to its original position when the sampling tube is removed for replacement with a fresh tube, so as to stop the flow of blood through the needle.
  • the instrument is also provided with indicator means which indicates the successful puncturing of a vein, when blood flows into the instrument.
  • sampling instruments are encumbered with a number of drawbacks and none of these known instruments fulfils the particular demands that can be placed on instruments of this kind.
  • the double-pointed needle cannot be handled easily by the personnel concerned, who are more accustomed to handling single-pointed needles in other contexts. The risk of injury when changing needles is high, particularly since the inner needle may have been contaminated by a previ ⁇ ous sample.
  • Blood sampling often requires more than one sampling ⁇ tube -to be filled, which involves an exchange of sam ⁇ pling tubes when only one vein puncture is made in the patient concerned.
  • a tube change unavoidably results in the spillage of blood, unless protective measures are taken.
  • the inner needle is often surrounded by an elastic casing which is pierced by the needle together with the rubber stopper fitted to the sampling tube, as taught by SE-B-425943.
  • SE-B-425943 the blood spillage is collect ⁇ ed in the elastic casing and is also deposited on the enclosed needle point.
  • An object of the present invention is to solve the aforesaid problems by providing a disposable sampling sleeve which is friendly to the patient and which can be handled safely and easily by the user.
  • the inventive sampling sleeve is comprised of one or a few simple components, all of which can be produced from readily machined materials of low kilo price.
  • a sampling sleeve of the kind described in the introduction is characterized in that it includes an inner needle which is intended to pierce the sampling-tube sealing device, and an outer, conical, standardized connector intended for connection to a standard vein-puncturing needle.
  • the connector orifice is connected with the needle orifice by an internal channel having arranged therein an internal valve which is closed when in an inactivated position and which is intended to be opened automatically by the tube sealing device when said device is pierced by the needle.
  • the external, standardized connector is formed inte ⁇ grally with the sampling sleeve and enables the use of needles selected from a conventional assortment of needles for sampling purposes. Since the cost of such needles only constitutes a fraction of the cost of the double-pointed needles, this solution affords a considerable reduction in the sampling cost for each patient treated. The use of the simpler form of needles also results in a considerable simplification and there ⁇ with in more rapid handling of the sampling instrument, which also contributes towards a reduction in cost.
  • the same insertion and standard needle as that used to take the sample can be used in said subsequent treatment, thereby relieving the patient of painful, repeated puncturing of the vein and also providing for quicker and more effective handling of the treatment.
  • the possibility of using a standard needle assortment also enables needles of different dimensions to be used with different patients.
  • the simple construction of the sampling sleeve from one or a few components produced from simple and inexpensive materials renders the sleeve viable for one-time-use only.
  • the structural design of the sleeve also enables simple valve means to be used, and in accordance with a preferred embodiment, the sleeve also includes an auto ⁇ matic non-return or check valve which prevents blood from flowing back from the sampling tube.
  • the simple sleeve construction also enables the provision of a simple blood indicator for indicating when a vein has successfully been punctured.
  • Figures la and lb are axial section views of the inventive device, where Figure la illustrates the sampling sleeve without the sampling tube connected thereto, and Figure lb illustrates the sampling sleeve with the sampling tube connected;
  • Figures 2a and 2b are section views taken on the lines 2a-2a and 2b-2b respectively in Figures la and lb;
  • FIGS. 3a and 3b illustrate two alternative embodi ⁇ ments of the flow valves included in the embodiments of Figures 1 and 2, with the valves being shown in their closed and open states respectively;
  • Figure 4 is an axial section view of an alternative embodiment of the invention.
  • FIG. 5 is an axial section view of a further alter ⁇ native embodiment of the invention.
  • Figures 6a and 6b illustrate still another alterna ⁇ tive embodiment of the invention illustrated in Figure 1;
  • Figures 7a and 7b illustrate a further alternative embodiment of the invention illustrated in Figure 1, and Figure 7c is a sectional view taken on the line 7c-7c in Figure 7a;
  • Figures 8a and 8b illustrate an alternative embodi ⁇ ment of the invention illustrated in Figure 1, including a non-return valve and blood indicator, and Figure 8c is an enlarged vertical sectional view of the valve head;
  • Figure 9a is a side view of an alternative embodiment of the cylindrical part of said sleeve
  • Figure 9b is a sectional view taken on the line 9b-9b in Figure 9a.
  • FIGS la,b - 2a,b illustrate an embodiment of a dis- posable sleeve 10 which incorporates a valve function, in accordance with the invention.
  • the open end of a sampling tube 12 is sealed by an elastic stopper 14, for instance a rubber stopper, in an airtight and liquid- tight fashion.
  • the stopper is formed so that it can be pierced by a needle and so that the hole formed by the needle will reseal automatically as the needle is with ⁇ drawn from the stopper.
  • the sampling tube 12 is evacu ⁇ ated of air, so as to generate an internal subpressure.
  • the disposable sleeve 10 is preferably a one-piece structure manufactured from a plastic material, and is open at one end thereof so as to enable the sampling tube 12 to be pushed into the cylindrical sleeve 10.
  • the other end of the sleeve 10 is provided with an end- part 15 which is provided with a centrally positioned, inwardly directed needle 16 and a preferably eccentri ⁇ cally positioned outwardly extending connector 22.
  • An angled channel 20 extends from one orifice in the con ⁇ nector 22, along the end-part 15 and through the inter- nal needle 16.
  • the connector 22 is a standardized fitting for standard injection needles and consists, for instance, of a Luer, Record or like standard fitting to which needles from a standard needle assortment can be connected.
  • the needle When taking a sample from the vein of a patient, the needle is preferably inserted in a direction which is as paral ⁇ lel as possible with the direction of the vein, since otherwise there is a risk of also piercing the back wall of the vein, particularly in the case of fine veins.
  • An eccentrically positioned connector 22 with a so-called Loeb-fitting enables the standard needle connected to the connector 22 to be inserted at a better angle than otherwise, therewith facilitating puncturing of the vein.
  • the connector 22 may also be placed centrally on the end-part 15, although the eccentric positioning of the connector is preferred, among other things because it facilitates puncturing of a vein, and because the lateral position of the connector provides more space for accommodating both a valve function and an indicat- ing function, as described in more detail herebelow.
  • the sampling sleeve illustrated in Figures 1-2 solves the problem of blood spillage when changing sampling tubes with one and the same needle inserted in the patient's vein, in that the inner needle 16 is formed inte-grally with a flow valve 26.
  • This inner flow valve 26 is formed in the needle between the obliquely cut needle point 18 and the end-part 15 of the sleeve, wherein in its non-activated state, the flow valve functions to close the passage through the angled chan ⁇ nel 20 between the connector 22 and the point of the needle.
  • the needle is made from a resilient material, and the flow valve is formed by biasing the walls into abutment with one another in one section of the needle, see Figures 2a-b, so as to close the channel and prevent blood from flowing therethrough.
  • the sampling tube with its rubber stopper 14, is pushed into the sleeve 10
  • the needle point 18 pierces and perforates the stopper.
  • the stopper reaches the valve section 26 of the needle, the elastic material from which the stopper is made presses against the end-parts 30 of the valve so as to open the inner passageway 20, as shown in Figure 2b, whereupon blood will be drawn into the sam ⁇ pling tube as a result of the subpressure prevailing therein.
  • the valve section 26 may also take other forms in its non-activated state, for instance the forms illustrated in Figures 3a and 3b.
  • the valve section will return to its original non-activated form, therewith immediately shutting-off the blood flow.
  • FIGs 4 and 5 illustrate two further valve means, both of which are formed integrally with the sampling sleeve 10.
  • the valve 26 has the form of a tongue 24 which forms an integral part of the end-part 15 above the channel 20, said tongue lying against the angled edge 25 of the channel such as to stop the flow of blood when the valve is in its non- activated state.
  • the tongue 24 is forced up by the stopper, therewith opening the valve and allowing blood to flow through the channel.
  • the needle is twisted about itself, so that the inner channel 20 is closed when the needle is in a non-activated state. As the twisted needle penetrates the rubber stopper, the needle is untwisted and therewith opens the channel 20.
  • FIGS 6a and b illustrate a further alternative em- bodiment of the flow valve 26.
  • two dia ⁇ metrically positioned wings 32 are formed integrally on the outside of the needle 16.
  • the channel 20 is provid ⁇ ed with two mutually opposing lips 34 which are formed integrally with the channel walls and which function to close the channel 20 when the wings 32 are in their non- activated, mutual positions, i.e. extend horizontally.
  • the wings 32 are forced upwards so as to mutual- ly separate the inner lips 34 and therewith open the channel 20.
  • the wings return to their neutral positions, and thus also the lips 34, therewith closing the channel.
  • the valve 26 is comprised of two separate parts, one of which is a centric pin 36 which is formed in ⁇ tegrally with the sleeve and the outer part of which widens into a spherical head 38.
  • the neck 40 of the pin 36 is provided with a number of symmetrically positioned grooves 42.
  • Firmly welded to the periphery of the inner end-part 15 of the sleeve 10 is a relatively rigid, but slightly elastic, plastic diaphragm 44.
  • the diaphragm 44 is curved around the head 38 and therewith forms an abutment surface 46 which, in a neutral position, sealingly abuts the spherical head 38 of the valve so as to close the blood passageway through the sampling sleeve.
  • the diaphragm continues from the abutment surface 46 to form a widened cavity 48 and thereafter tapers to form a pointed needle 16.
  • the bottom of the sleeve 10 is also provided with internal grooves 50, the function of which will be described herebelow.
  • Figure 7b illustrates how the valve 26 is opened when the sampling tube, together with the rubber stopper, is pushed into the sleeve.
  • the diaphragm 44 is pushed up against the bottom of the sleeve and in its furthest inserted position lies against the grooves 50 on said bottom surface.
  • the grooves 50 on the bottom surface and the grooves 42 on the pin ensure that blood will flow uniformly through the passageway.
  • the sampling sleeve illustrated in Figure 7 may be provided with a non-return valve, for instance in the form of a flexible, funnel-shaped flange mounted on the underside of the spherical head.
  • the downwardly hanging flange is forced to one side by the blood that flows into the cavity 48 and from there into the sampling tube. If, on the other hand, there occurs a drop in pressure in the vein or an increase in pres ⁇ sure in the sampling tube, the soft and pliant flange is forced out into sealing contact with the inner walls of the cavity, therewith preventing backward flow of the blood.
  • FIGs 8a-8 ⁇ illustrate a preferred embodiment having a valve means 26 which, in this case, also functions as an automatic non-return valve.
  • the valve means operates automatically in the event of a drop in pressure in the vein or in the event of a pressure increase in the sampling tube. This function is particularly important when using sampling tubes that contain different mixture substances which must not be allowed to flow back to the patient.
  • the valve means 26 is displaceably mounted in an annular flange 52 formed integrally with the bottom of the disposable sleeve, as illustrated in Figure 8a. When the valve 26 is in the operational state illustrated in Figure 8a, the valve seals against the side of the annular flange so as to stop the flow of blood through the passage.
  • the valve body is comprised of two parts, partly a resilient, elastic rubber body 54 having a tubular lip 56, and partly a needle part 58.
  • the needle part 58 is preferably made of a plastic material and consists of the needle 16 which is intended to penetrate or pierce the rubber plug 14 of the sampling tube, and of a sleeve 60 which is open at one end there ⁇ of and the outer diameter of which is slightly smaller than the inner diameter of the annular flange 52.
  • the sleeve is provided with an opening 62 through which blood is intended to flow when the valve is open.
  • the tubular lip 56 is arranged within the sleeve 60, as shown in Figure 8c.
  • valve body 26 is pressed against the end-part 15 of the sleeve.
  • the elastic body 54 is thereby com- pressed, as shown in Figure 8b, so as to uncover the opening 62 in the valve sleeve 60 earlier covered by the sealing annular flange 52, such that the opening dis ⁇ charges into the channel 20. Blood will then flow through the channel and force the lip 56 to one side and continue down into the sampling tube.
  • parts of the end-part 15 may be formed so as to spring- up slightly under the pressure exerted by the valve body, as shown in broken lines in Figure 8b.
  • the occurrent pressure difference causes the tubular lip 56 to be pressed against the inner wall of the sleeve 60, thereby closing the passage 62 and preventing the flow of fluid back to the patient.
  • the lip 56 is flexed to one side so as to permit the flow of fluid.
  • the elastic body 54 and/or the resil ⁇ ient end-part 15 will spring back so as to again cover the opening 62 in the valve body with the inner walls of the annular flange 52.
  • a blood indicator 66 is arranged in the channel 20.
  • the end-part 15 of the sampling sleeve is made of a transparent plastic material, so as to enable the indicator to be seen from the outside. It is imper- ative that the indicator will offer the minimum of resistance to flow, so that venous blood is able to flow into the indicator without the assistance of a subpres ⁇ sure in the sampling tube.
  • a bag-membrane 68 which is essentially empty of air and which when successfully penetrating a vein is filled with blood in the absence of any appreciable flow resistance.
  • the blood-filled bag-membrane can be seen from outside the sampling sleeve, through the plastic material, thereby indicating that a vein has been punc- tured successfully and allowing the sampling tube to be connected to the sampling sleeve.
  • the blood indicator may have the form of a part of the channel 20 which can be seen through the plastic materi ⁇ al of the end-part and which is connected to an expand- able hose which is empty of air and which can accommo ⁇ date the air that is displaced by the blood entering the blood indicator, such that said channel part will be filled with blood in the absence of any resistance when a vein is successfully punctured.
  • FIGs 9a and 9b illustrate an embodiment of the dis ⁇ posable sleeve 10 in which the cylindrical part of said sleeve is adapted to accommodate sampling tubes of mutually different dimensions, for example so-called pediatric tubes of smaller diameter.
  • the cylindrical part of the disposable sleeve 10 is replaced with a thin cylindrical wall 70 which is stiffened by a plurality, preferably four, support bars 72 which extend along said wall, as shown in Figure 9b.
  • the thin cylindrical wall 70 is free from the end-part
  • one of the support bars 72 may be disconnected from the end-part 15.
  • the disconnected support-bar 72, together with the encircling thin wall-parts 70, can then be pressed in against the opposite part of the cylindrical wall, so that the previously cylindrical sleeve now assumes a stackable U-shape.
  • the free support bar 72 and the encircling wall-parts are pressed back to their original positions.
  • a flexible tongue or flap may be attached to the wall of the channel 20 in some suitable manner, inwardly of the connector 22, such as to form a non-return valve.

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Medical Informatics (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • Hematology (AREA)
  • Veterinary Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Vascular Medicine (AREA)
  • Manufacturing & Machinery (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)

Abstract

L'invention se rapporte à un cylindre de prélèvement d'échantillons sanguins, qui est destiné à coopérer avec un tube de prélèvement d'échantillons sanguins dans lequel règne une dépression interne et qui est scellé à l'une de ses extrémités, pour empêcher l'entrée d'air et de liquide au moyen d'un dispositif de fermeture étanche pouvant être percé ou pénétré par une aiguille. Ce cylindre de prélèvement d'échantillons est constitué par une structure en une seule pièce destinée à un usage unique seulement. Le cylindre est conçu facile à utiliser et sans risque pour l'utilisateur, pour pouvoir être manipulé avec aisance et rapidité. Le cylindre contient une aiguille interne (16) destinée à percer le dispositif de fermeture étanche (14) adapté au tube de prélèvement d'échantillons (12), ainsi qu'un raccord conique externe standardisé (22) destiné à être raccordé à une aiguille pour piqûre de veines standard. Un canal interne (20) relie l'orifice du raccord à l'orifice de l'aiguille et un clapet interne (26) est prévu dans le canal (20). Le clapet (26) est fermé en période d'inactivité et il est destiné à s'ouvrir automatiquement sous l'action du dispositif de fermeture étanche (14) du tube de prélèvement d'échantillons, lorsque l'aiguille (16) pénètre dans ledit dispositif de fermeture étanche.
PCT/SE1991/000617 1990-09-17 1991-09-16 Dispositf de prelevement d'echantillons sanguins WO1992004867A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE9002960A SE467442B (sv) 1990-09-17 1990-09-17 Engaangshylsa foer venoes provtagning enligt vakuumroersmetodiken
SE9002960-4 1990-09-17

Publications (1)

Publication Number Publication Date
WO1992004867A1 true WO1992004867A1 (fr) 1992-04-02

Family

ID=20380381

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/SE1991/000617 WO1992004867A1 (fr) 1990-09-17 1991-09-16 Dispositf de prelevement d'echantillons sanguins

Country Status (2)

Country Link
SE (1) SE467442B (fr)
WO (1) WO1992004867A1 (fr)

Cited By (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995016395A1 (fr) * 1993-12-16 1995-06-22 C.A. Greiner & Söhne Gesellschaft M.B.H. Systeme de fixation pour tube de prelevement sanguin d'un dispositif pour prise de sang
EP0916307A1 (fr) * 1997-11-13 1999-05-19 C.G.M. S.P.A. Dispositif pour le prélèvement des liquides corporels et pour les transférer dans des éprouvettes
EP1027864A1 (fr) * 1999-02-12 2000-08-16 Dino Cagetti Dispositif de prélèvement sanguin utilisant une éprouvette sous vide
EP1266618A1 (fr) * 2001-06-11 2002-12-18 Long-Hsiung Chen Seringue de sécuritéà forme ergonomique pour prise de sang
US7118538B2 (en) 2004-07-19 2006-10-10 Greiner Bio-One Gmbh Holding device for a medical device
JP2017042641A (ja) * 2010-11-09 2017-03-02 セブンス センス バイオシステムズ,インコーポレーテッド 血液サンプリングのためのシステムおよびインターフェース
RU2651076C2 (ru) * 2013-08-29 2018-04-18 Импрув Медикал Инструментс (Хунань) Ко., Лтд. Устройство для прокалывания гепаринового колпачка и система сосудистого доступа
US10188335B2 (en) 2011-04-29 2019-01-29 Seventh Sense Biosystems, Inc. Plasma or serum production and removal of fluids under reduced pressure
US10543310B2 (en) 2011-12-19 2020-01-28 Seventh Sense Biosystems, Inc. Delivering and/or receiving material with respect to a subject surface
US10799166B2 (en) 2009-03-02 2020-10-13 Seventh Sense Biosystems, Inc. Delivering and/or receiving fluids
US10835163B2 (en) 2011-04-29 2020-11-17 Seventh Sense Biosystems, Inc. Systems and methods for collecting fluid from a subject
US10939860B2 (en) 2009-03-02 2021-03-09 Seventh Sense Biosystems, Inc. Techniques and devices associated with blood sampling
US11177029B2 (en) 2010-08-13 2021-11-16 Yourbio Health, Inc. Systems and techniques for monitoring subjects
US11202895B2 (en) 2010-07-26 2021-12-21 Yourbio Health, Inc. Rapid delivery and/or receiving of fluids

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3659587A (en) * 1970-06-30 1972-05-02 Affiliated Hospital Prod Valved connector arrangement
US3874367A (en) * 1972-06-29 1975-04-01 Becton Dickinson Co Valved blood sampling needle assembly
US4280509A (en) * 1977-11-11 1981-07-28 Bethkenhagen Juergen Valved blood sampling device
WO1987006813A1 (fr) * 1986-05-14 1987-11-19 Lamberto Roberti Aiguille pour dispositifs de prelevement sous-vide d'echantillons sanguins multiples
EP0323903A1 (fr) * 1988-01-08 1989-07-12 Allflex Europe S.A. Dispositif de prélèvement de liquides à usage unique
WO1989010723A1 (fr) * 1988-05-02 1989-11-16 Nielsen Bjoern Equipement de prelevement d'echantillons sanguins avec aiguille, cylindre de support et fiole sous vide

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3659587A (en) * 1970-06-30 1972-05-02 Affiliated Hospital Prod Valved connector arrangement
US3874367A (en) * 1972-06-29 1975-04-01 Becton Dickinson Co Valved blood sampling needle assembly
US4280509A (en) * 1977-11-11 1981-07-28 Bethkenhagen Juergen Valved blood sampling device
WO1987006813A1 (fr) * 1986-05-14 1987-11-19 Lamberto Roberti Aiguille pour dispositifs de prelevement sous-vide d'echantillons sanguins multiples
EP0323903A1 (fr) * 1988-01-08 1989-07-12 Allflex Europe S.A. Dispositif de prélèvement de liquides à usage unique
WO1989010723A1 (fr) * 1988-05-02 1989-11-16 Nielsen Bjoern Equipement de prelevement d'echantillons sanguins avec aiguille, cylindre de support et fiole sous vide

Cited By (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995016395A1 (fr) * 1993-12-16 1995-06-22 C.A. Greiner & Söhne Gesellschaft M.B.H. Systeme de fixation pour tube de prelevement sanguin d'un dispositif pour prise de sang
US5897508A (en) * 1993-12-16 1999-04-27 C.A. Greiner & Sohne Gesellschaft M.B.H. Holding device for a blood sample removal tubule of a blood removal device
EP0916307A1 (fr) * 1997-11-13 1999-05-19 C.G.M. S.P.A. Dispositif pour le prélèvement des liquides corporels et pour les transférer dans des éprouvettes
US6113555A (en) * 1997-11-13 2000-09-05 C.G.M. S.P.A. Device for withdrawing body liquids and for transferring them into sample tubes
EP1027864A1 (fr) * 1999-02-12 2000-08-16 Dino Cagetti Dispositif de prélèvement sanguin utilisant une éprouvette sous vide
EP1266618A1 (fr) * 2001-06-11 2002-12-18 Long-Hsiung Chen Seringue de sécuritéà forme ergonomique pour prise de sang
US7118538B2 (en) 2004-07-19 2006-10-10 Greiner Bio-One Gmbh Holding device for a medical device
US10799166B2 (en) 2009-03-02 2020-10-13 Seventh Sense Biosystems, Inc. Delivering and/or receiving fluids
US10939860B2 (en) 2009-03-02 2021-03-09 Seventh Sense Biosystems, Inc. Techniques and devices associated with blood sampling
US12076518B2 (en) 2010-07-26 2024-09-03 Yourbio Health, Inc. Rapid delivery and/or receiving of fluids
US11202895B2 (en) 2010-07-26 2021-12-21 Yourbio Health, Inc. Rapid delivery and/or receiving of fluids
US11177029B2 (en) 2010-08-13 2021-11-16 Yourbio Health, Inc. Systems and techniques for monitoring subjects
JP2017042641A (ja) * 2010-11-09 2017-03-02 セブンス センス バイオシステムズ,インコーポレーテッド 血液サンプリングのためのシステムおよびインターフェース
US10835163B2 (en) 2011-04-29 2020-11-17 Seventh Sense Biosystems, Inc. Systems and methods for collecting fluid from a subject
US10188335B2 (en) 2011-04-29 2019-01-29 Seventh Sense Biosystems, Inc. Plasma or serum production and removal of fluids under reduced pressure
US11253179B2 (en) 2011-04-29 2022-02-22 Yourbio Health, Inc. Systems and methods for collection and/or manipulation of blood spots or other bodily fluids
US10543310B2 (en) 2011-12-19 2020-01-28 Seventh Sense Biosystems, Inc. Delivering and/or receiving material with respect to a subject surface
RU2651076C2 (ru) * 2013-08-29 2018-04-18 Импрув Медикал Инструментс (Хунань) Ко., Лтд. Устройство для прокалывания гепаринового колпачка и система сосудистого доступа

Also Published As

Publication number Publication date
SE467442B (sv) 1992-07-20
SE9002960D0 (sv) 1990-09-17
SE9002960L (sv) 1992-03-18

Similar Documents

Publication Publication Date Title
US3494352A (en) Apparatus for taking multiple samples
US5453097A (en) Control of fluid flow
US6325782B1 (en) Medical valve with fluid escape space
US4244379A (en) Check valve for blood drawing apparatus
JP3448293B2 (ja) 予めスリットが設けられたシールを有する接続装置
US5843046A (en) Catheter apparatus
US5700248A (en) Medical valve with tire seal
JP4323721B2 (ja) ルア受け具及び流体の移送方法
US4972843A (en) Sample taking equipment
US5776113A (en) Valved PRN adapter for medical access devices
EP0049591B1 (fr) Aiquille d'échantillonnage à usage unique munie d'un indicateur d'accès de veine
EP0071329B1 (fr) Canule pour prélèvements multiples de sang
US5961472A (en) Closed, one-handed blood sampling system
US5065783A (en) Valve with self-sealing internal cannula
US5067950A (en) Wound drainage tube/reservoir connector
EP0484092A1 (fr) Cathéter avec un clapet automatique
US5324256A (en) Apparatus and methods for transferring blood between aspiration assembly and an external container
EP0783899A2 (fr) Appareil de prise d'échantillons de sang
WO1992004867A1 (fr) Dispositf de prelevement d'echantillons sanguins
WO1997021464A9 (fr) Valve medicale avec un espace permettant a du fluide de s'echapper
EP1747755B1 (fr) Structure antireflux pour dispositif de prélèvement sanguin, aiguille luer lock, aiguille pour prélèvement sanguin et porte-prélèvements
GB1603187A (en) Assemblies for collecting blood or other fluids
US5562639A (en) Vented fluid collection system
JP4007681B2 (ja) 翼付採血針
CN108324291B (zh) 血样采集防逆流阀装置及采血针

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A1

Designated state(s): BR CA JP KR US

AL Designated countries for regional patents

Kind code of ref document: A1

Designated state(s): AT BE CH DE DK ES FR GB GR IT LU NL SE

122 Ep: pct application non-entry in european phase
NENP Non-entry into the national phase

Ref country code: CA