WO1991003297A1 - Procede et dispositif pour la separation de substances par adsorption - Google Patents

Procede et dispositif pour la separation de substances par adsorption Download PDF

Info

Publication number
WO1991003297A1
WO1991003297A1 PCT/EP1990/001502 EP9001502W WO9103297A1 WO 1991003297 A1 WO1991003297 A1 WO 1991003297A1 EP 9001502 W EP9001502 W EP 9001502W WO 9103297 A1 WO9103297 A1 WO 9103297A1
Authority
WO
WIPO (PCT)
Prior art keywords
adsorbent
medium
belt
separated
slot
Prior art date
Application number
PCT/EP1990/001502
Other languages
German (de)
English (en)
Inventor
Wolfgang Demmer
Dieter Nussbaumer
Abdul Razak Weiss
Eberhard Wünn
Original Assignee
Sartorius Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sartorius Ag filed Critical Sartorius Ag
Publication of WO1991003297A1 publication Critical patent/WO1991003297A1/fr

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J47/00—Ion-exchange processes in general; Apparatus therefor
    • B01J47/12—Ion-exchange processes in general; Apparatus therefor characterised by the use of ion-exchange material in the form of ribbons, filaments, fibres or sheets, e.g. membranes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/02—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor with moving adsorbents
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D2215/00—Separating processes involving the treatment of liquids with adsorbents
    • B01D2215/02—Separating processes involving the treatment of liquids with adsorbents with moving adsorbents
    • B01D2215/022—Physically moving the adsorbent as a whole, e.g. belts, discs or sheets

Definitions

  • the invention relates to a method for adsorptive
  • Adsorptive separation of substances is understood to mean the reversible binding of substances from fluids to solid surfaces.
  • the most important mechanisms involved are ion exchange, hydrophobic interactions, chelation and specific interactions, such as those that occur in affinity chromatography or in the formation of immune complexes. Combinations of these mechanisms are also conceivable, which are not yet fully known in detail.
  • An example of the latter ⁇ ⁇ ⁇ case is the reversible binding of certain enzymes to dyes anchored on a solid matrix.
  • Adsorption of substances on solid surfaces can occur from both the liquid and the gas phase
  • the method according to the invention and the device according to the invention preferably have the object of adsorption from liquid phases, but they can also be used in gas phases.
  • Substances, e.g. B. by affinity chromatography is as
  • Base material for such gels agarose in use which is modified to achieve the specific adsorption properties by fixing appropriate ligands.
  • Micropores have significant kinetic advantages over the swollen gel-like matrix, i. H. both loading and regeneration are much faster.
  • the invention has for its object to provide a method un 25 a device for adsorptive material separation with a flat microporous adsorbent, which is transported relative to the medium to be separated, which are economical with high efficiency.
  • a convective mass transfer 35 is achieved within the micropores of the adsorbent by applying a pressure gradient. This can significantly accelerate the exchange cone of granular, microporous adsorbents based on diffusion Adsorption and desorption (loading and regeneration) can be achieved.
  • a flat adsorbent that meets the above requirements to a high degree consists of a microporous membrane filter, consisting of a synthetic polymer, the outer and inner surface of which has a chemical modification that brings about the required specific adsorption properties. To ensure the required tensile strength, the adsorbent is provided with an integrated reinforcement material made of polyester fleece.
  • a region already passed through the medium to be separated flows through a rinsing medium and in each case preceding regions through a desorption medium or a regeneration and equilibration medium, and then the regenerated and equilibrated adsorbent is added again
  • This continuous form of the method according to the invention not only has general economic advantages, but also the advantage but also the advantage that you can work with a minimum of adsorbent. This is because the adsorbent regenerates immediately after loading and is fed to the new loading.
  • different media flow through the adsorbent discontinuously in time i.e. H. there is a batch process in which the rinsing process, i.e. H. the flow of the rinsing medium through the adsorbent takes place when the adsorption step, d. H. loading of the adsorbent is complete.
  • the desorption step is carried out again using a desorption medium for the complete adsorbent, after which the regeneration and equilibration step follows.
  • the medium that has flowed through the adsorbent is kept separate from the supplied medium or output ediurn, or there is no separation of the starting medium from the medium that has already flowed through the adsorbent.
  • the flow through the adsorbent can either take place in such a way that the supply and discharge of the medium are spatially separated, which essentially corresponds to filtration, or there is no spatial separation, ie the medium reunites with the starting medium after the adsorbent has flowed through it.
  • the former case is generally preferable, i.e. H. the separation of supply and discharge of the medium. It is possible to completely remove the substance to be adsorbed from the medium, while in the case in which the medium is reunited with the starting medium after flowing through the adsorbent, only a more or less strong depletion is possible. In applications in which a pollutant is to be removed as completely as possible, for example when removing heavy metals from waste water, this plays an important role. However, there are also cases in which a higher quality substance is to be obtained from a lower quality starting medium. Here it can prove to be economically viable to focus on a specific one
  • the flat, microporous adsorbent is in motion, while in a part of the device a convective transport of the fluid to be treated is maintained by the adsorbent.
  • the band-shaped adsorbent is transported more or less quickly through this part of the device, whereupon it can either be rolled up for later treatment (rinsing, desorpti regeneration) or can be exposed to these treatment steps in a further step.
  • it it is a discontinuous embodiment of the device according to the invention
  • it is a continuous one, namely when the adsorbent is in the form of an endless belt and the medium to be treated is applied again immediately after the regeneration.
  • a continuously operating device is preferable for economic reasons and for the cost of shorter treatment times.
  • the adsorbent belt is guided around a slot nozzle arranged in a container and a line with a pump is provided to the slot nozzle.
  • a plurality of slot nozzles fed with the medium contained in the container are arranged one behind the other, wherein Adsorbent tape preferably zigzag around the
  • the adsorbent band is preferably wider than the slot of the slot nozzle.
  • the edges of the adosorbent tape lie sealingly on the housing of the slot nozzle next to the latter, so that sufficient tightness is achieved and it is ensured that the medium can flow almost completely through the adsorbent tape.
  • the device with a slot nozzle there is generally no separation of the inlet and outlet of the medium to be treated, but devices with a separation of inlet and outlet are also conceivable.
  • the adsorbent belt is guided around a sieve drum which is designed with a feed and is arranged above a trough.
  • the adsorbent belt is preferably made wider than the perforated surface of the sieve drum, so that the belt with its long edges in turn lies sealingly against the sieve drum and it is ensured that the medium to be treated only flows through the adsorbent belt.
  • deflection and / or tensioning rollers are preferably provided, over which the adsorbent belt runs.
  • each end of the adsorbent belt is attached to a winding drum.
  • Each of the winding drums is rotatably driven, so that the adsorbent belt can be wound alternately on the one and the other roll at a selectable speed 0, whereby it is guided along a slot nozzle or a sieve drum.
  • Such a device is operated discontinuously.
  • Such a device is operated continuously, i. H. the adsorbent belt is fed to appropriate devices after passing it through a slot nozzle or sieve drum 0, in which it is flowed through by a rinsing medium, an elution medium and an equilibration medium.
  • the discontinuous device also has its justification because it is simpler in terms of equipment and, for example, when working out a technical process, the effects of individual process parameters are examined independently of one another can be. In this way, the optimal dwell times within the individual stages can expediently be investigated, which enables the prerequisite for * the optimal dimensioning of the treatment units which are run through in the g 5 continuous process.
  • the optimal dwell times within the individual stages can expediently be investigated, which enables the prerequisite for * the optimal dimensioning of the treatment units which are run through in the g 5 continuous process.
  • much larger quantities of liquid have to be processed during the absorption than during the rinsing and elution steps.
  • 1 is a schematic representation of a discontinuously working device for adsorptive material separation
  • FIG. 2 shows a modified embodiment of a device for adsorptive material separation
  • FIG. 3 shows a schematic representation of a continuously operating device for adsorptive material separation
  • Fig. 4 is a section along the line IV / IV of Fig. 3, and
  • the discontinuously operating device 10 for adsorptive material separation shown in FIG. 1 has a container 12 in which two rotationally driven winding drums 14 and 16 are arranged.
  • the winding drums 14 and 16 serve to alternately wind up an adsorbent tape 13.
  • the adsorbent tape 13 is fastened at one end to the winding drum 14 and at the other end to the winding drum 16.
  • Deflection rollers 20 and 22 are also arranged in the container, via which the belt is led.
  • a slot nozzle 26 is arranged, around which the band 18 is guided.
  • the 26 can be designed in the form of a tube into which an elongated hole is cut.
  • the band 18 is slightly wider than the slot 30 in the slot nozzle 26 so that the side edges seal against the body of the
  • Slit nozzle 26 abuts. From the lower area 24 of the
  • Container 12 is a line 32 into which a
  • Circulation pump 34 is switched on. Line 34 is to d
  • FIG. 2 shows a device for adsorptive material separation by means of a flat, microporous adsorbent, a plurality of slot nozzles 42, 44, 46, 48, 50 being arranged in a container or tank 40.
  • the slots of two adjacent nozzles 42 to 50 are directed in opposite directions, so that an adsorbent band 52 is guided in a zigzag pattern around slot nozzles 42 to 50.
  • the tape is in the
  • Container 40 is still guided around deflection and / or tensioning rollers 54, 56 and outside the container around deflection rollers 58, 60.
  • the adsorbent belt 52 can be fastened at one end to winding drums (not shown), or it can be ducked as an endless belt via suitable Uinlenkele. Through the opposite slots Adjacent to the slot nozzles, the adsorbent belt 52 is alternately guided past the slot nozzles with one side and the other. Effective flushing of deposited particles is achieved with particle-containing suspensions.
  • Slot nozzles 42 to 50 is supplied is not shown in Fig. 2. 2 can be operated continuously or discontinuously.
  • FIG. 3 shows an embodiment of a continuously operating device for adsorptive material separation by means of a flat microporous adsorbent.
  • An adsorbent belt 70 is guided around a sieve drum 72, which is arranged above a trough 74.
  • Medium 76 to be processed is introduced into the screening drum 72.
  • the medium 76 flows through the adsorbent belt 70 guided around the sieve drum 72, reaches the trough 74 as treated medium 78 and can be discharged via a line 80.
  • the adsorbent belt 70 is guided from the sieve drum 72 via a deflection roller 82 around a sieve drum 84, which is arranged above a trough 86 from which a line 88 extends.
  • Flushing medium 90 is contained in the sieve drum 84 and flows through the adsorbent belt 70 while it is running around the sieve drum 84. Flushing medium 92 which has flowed through the belt 70 is collected in the tub 86 and can be removed via the line 88.
  • the adsorbent belt 70 is guided over a deflection roller 94 around a sieve drum 96, which is arranged over a trough 98.
  • the elution medium 100 is contained in the sieve drum 96 and flows through the adsorbent belt 70 while it is being guided around the sieve drum 96.
  • Elution medium which has flowed through the adsorbent belt 70 is collected in the tub 98 and can be removed therefrom. From the sieve drum 96, the adsorbent belt 70 is a
  • Trough 106 is arranged and in the sieve drum 102
  • Equilibrium edium 108 included, which flows through the sieve drum 102 while the adsorbent belt 70 is running and is collected in the tub 106, from which it can be removed via a line 110
  • the adsorbent belt 70 is guided around a web tension control roller or tensioning roller 112 and after it around a deflection roller 114 in order to reach the screening drum 72 again.
  • Each of the sieve drums 72, 84, 96 and 102 has closed end walls and the perforated cylindrical surfaces of the sieve drums have a width which is less than the width of the adsorbent belt 70.
  • Fig. 4 shows a section through the sieve drum 72.
  • the perforations 116 provided cylinder 118 of the sieve drum is provided at both ends with end walls 120 and 122, on which axle stubs 124 and 126 are arranged for mounting the sieve drum, via a motor 128 the sieve drum 72 is driven.
  • the area of the cylinder 118 provided with the perforations 116 has a width which is less than the width of the adsorbent belt 70, so that the edges 130 and 132 of the adsorbent belt 70 seal against the cylinder 118 of the sieve drum 72.
  • the sieve drums 84, 96 and 102 are of similar design, so that the edges of the adsorbent band also lie there sealingly against the cylindrical, non-perforated outer surface regions d of the sieve drums.
  • the medium 76 to be processed is in the
  • treatment with alkali can be carried out here, for example, to remove firmly adhering impurities.
  • the size of the sieve drums 72, 84, 96 and 102 can be different if required. In general, the largest volumes will occur in the medium to be treated, so that the largest drum (sieve drum 72) is used there.
  • a device such as that corresponding to the device shown in FIG. 1 was used to carry out the tests.
  • the device essentially consisted of a winding and an unwinding roller for the adsorbent belt, a trough for the medium to be treated, as well as deflection rollers and a slot nozzle.
  • a mechanical device caused the tape to be wound at a selectable speed alternately on one and on the other roll, each by the Medium.
  • the width of the absorbent tape was 30 cm.
  • the slot nozzle consisted of a 20 mm diameter stainless steel tube with a milled slot 0.3 mm wide. The slot was slightly shorter than the width of the adsorbent tape used, so that the ends of the slot were covered by the tape sliding over it.
  • the slot nozzle was connected to a pump with which the medium in the tub could be pumped through.
  • a dye-modified membrane was used as the adsorbent tape, the technical data of which are summarized in Example 1 and which, for example, according to
  • Example 1 represents a counterexample not according to the invention, in which the device described was operated without pumping around the medium. In principle, this mode of operation corresponds to a conventional batch operation of an adsorbent, which is also possible with granular adsorbents.
  • the advantage of the flat adsorbent over the above is only that it is more convenient to use, ie no filtration or centrifugation steps are required for the separation from the medium to be treated, but a simple winding is sufficient.
  • the medium was pumped through the slit nozzle while the membrane band was being pulled past it.
  • Example 1 (counter example):
  • This medium was filled into the trough of the test apparatus (analogous to the embodiment according to FIG. 1), a 28 cm wide band of the membrane material was used and a web speed of 1.3 m / min. moved back and forth in the bathroom.
  • the wetted belt length was 2.1 m, corresponding to an area of 0.6 itfi.
  • the main technical data of this material were:
  • Dye ligand Cibacron blue F3GA thickness: 190 / u m
  • the circulation pump was not put into operation.
  • the MDH activity in the medium was determined over a period of 3 hours.
  • the MDH removal in the medium with the test time is shown graphically in FIG. 5.
  • the decrease in MDH activity over time was practically linear, with about 55% of the initial activity remaining in the medium after 3 hours.
  • Example 2 The experiment according to Example 1 was carried out using the circulation pump at a circulation rate of 250 l / h. repeated.
  • the MDH decrease with time is also shown in FIG. 5.
  • the cell homogenate was removed from the tub of the apparatus and replaced by 0.05 M K-phosphate buffer pH 7. Belt movement and circulation continued so that the loaded membrane was rinsed. This process was carried out a total of three times for a period of 5 minutes each, the rinsing liquid being renewed each time.

Landscapes

  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)

Abstract

Dans la séparation de substances par adsorption avec un adsorbant microporeux mince pouvant être transporté par rapport au milieu à séparer, l'adsorbant est traversé par le milieu. Il en résulte un transport par convection du fluide à traiter par l'adsorbant. L'adsorbant, qui a de préférence la forme d'un ruban, est transporté avec une vitesse appropriée et, après avoir été traversé par le milieu à séparer, il est enroulé en vue d'un nouveau traitement ultérieur (rinçage, désorption, régénération) ou exposé directement à des milieux de traitement dans des étapes ultérieures. Dans le dispositif servant à la séparation des substances par adsorption au moyen d'un adsorbant microporeux mince pouvant être transporté par rapport au milieu à séparer, l'adsorbant se présente sous la forme d'un ruban guidé et entraîné par des cylindres (72, 84, 96, 102), le milieu à séparer (76) étant guidé ou s'écoulant par le ruban adsorbant (70) sous l'action de la pesanteur ou de la pression. Le dispositif peut fonctionner en mode discontinu ou continu.
PCT/EP1990/001502 1989-09-06 1990-09-06 Procede et dispositif pour la separation de substances par adsorption WO1991003297A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DEP3929643.1 1989-09-06
DE3929643 1989-09-06

Publications (1)

Publication Number Publication Date
WO1991003297A1 true WO1991003297A1 (fr) 1991-03-21

Family

ID=6388764

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP1990/001502 WO1991003297A1 (fr) 1989-09-06 1990-09-06 Procede et dispositif pour la separation de substances par adsorption

Country Status (2)

Country Link
DE (1) DE4028357C2 (fr)
WO (1) WO1991003297A1 (fr)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2274843A (en) * 1993-02-09 1994-08-10 Agricultural & Food Res Method and apparatus for the continuous separation and purification of material
AT400309B (de) * 1994-05-27 1995-12-27 Alois Dr Jungbauer Kontinuierlich arbeitende trennanlage

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2751087A (en) * 1953-04-18 1956-06-19 Wallquist Ivar Movable bed type filter for liquids
FR1460877A (fr) * 1965-10-21 1966-01-07 Filtres Philippe Soc D Filtre rotatif à déroulement de médium filtrant
DE1914139A1 (de) * 1969-03-20 1970-10-01 Bran & Luebbe Verfahren und Vorrichtung zum kontinuierlichen Ionenaustausch in Fluessigkeiten
US3826370A (en) * 1973-05-29 1974-07-30 Technical Fab Inc Rotary filter apparatus having means for controlling the level of filtrate

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1069602B (de) * 1955-04-28 1959-11-26 Vereinigte Glanzstoff Fabriken A G Wuppertal Fiberfeld Verfahren und Vorrichtung zur Adsorption von Glycolen aus flussigen Kohlenwasserstoffen
CS159406B1 (fr) * 1971-09-03 1975-01-31
DE2713963A1 (de) * 1977-03-29 1978-10-12 Wieland Carl Paul Selektive filtermembran
GB2192403B (en) * 1986-07-09 1990-04-11 George Edward Jowett Improvements to solid/liquid reactions using a continous belt of sponge material

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2751087A (en) * 1953-04-18 1956-06-19 Wallquist Ivar Movable bed type filter for liquids
FR1460877A (fr) * 1965-10-21 1966-01-07 Filtres Philippe Soc D Filtre rotatif à déroulement de médium filtrant
DE1914139A1 (de) * 1969-03-20 1970-10-01 Bran & Luebbe Verfahren und Vorrichtung zum kontinuierlichen Ionenaustausch in Fluessigkeiten
US3826370A (en) * 1973-05-29 1974-07-30 Technical Fab Inc Rotary filter apparatus having means for controlling the level of filtrate

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2274843A (en) * 1993-02-09 1994-08-10 Agricultural & Food Res Method and apparatus for the continuous separation and purification of material
EP0611066A1 (fr) * 1993-02-09 1994-08-17 AGRICULTURAL & FOOD RESEARCH COUNCIL Séparation et purification continues de matières
GB2274843B (en) * 1993-02-09 1997-02-26 Agricultural & Food Res Continuous separation and purification of materials
AT400309B (de) * 1994-05-27 1995-12-27 Alois Dr Jungbauer Kontinuierlich arbeitende trennanlage

Also Published As

Publication number Publication date
DE4028357C2 (de) 1999-10-07
DE4028357A1 (de) 1991-03-07

Similar Documents

Publication Publication Date Title
DE69112197T2 (de) Verfahren zur Regeneration poröser keramischer Filter.
EP0643615B1 (fr) Procede et dispositif de preparation en vue de la production d'eau pure
DE4432627B4 (de) Filtrationseinheit zur Abtrennung von Stoffen mit Membranadsorbern
DE10327988B4 (de) Filtermodul zur Aufbereitung von Flüssigkeiten
EP0050813B1 (fr) Filtre d'adsorption à contre-courant pour traiter des liquides et procédé pour son fonctionnement
DE4030084A1 (de) Rueckspuelfilter
DE19943921C1 (de) Partikelgängige Vorrichtung zur Durchführung von Stofftrennungen mittels poröser flächiger Adsorptionsmembranen
DE69701514T2 (de) Methode und vorrichtung zur wasserreinigung
DE3390031T1 (de) Vorrichtung zum Behandeln von Wasser
DE2355422A1 (de) Verfahren und vorrichtung zur behandlung von fluessigkeit
CH634757A5 (de) Verfahren und vorrichtung zur abscheidung von schwebstoffen aus suspensionen durch absitz- und filterverfahren.
DE4028357C2 (de) Verfahren und Vorrichtung zur adsorptiven Stofftrennung
DE1008712B (de) Filterdrahtsystem zur Filterung von Fluessigkeiten
EP0968038B1 (fr) Procede et installation pour separation de matieres par adsorption
DE2323312C3 (de) Verfahren und Vorrichtung zum Aufbereiten von bei der Behandlung von Flüssigkeiten beladenem Absorbermaterial
DE3325203C2 (fr)
DE1536826C3 (de) Filtervorrichtung
DE2356793C2 (de) Vorrichtung zur Behandlung eines fließfähigen Mediums durch Kontakt mit Feststoffpartikeln
DE2420744C3 (de) Vorrichtung zum Reinigen von Abwasser
EP0583262B1 (fr) Procede et dispositif de separation de substances notamment solides ou coagulees contenues dans des liquides et/ou de concentration de solutions au moyen d'une vis convoyeuse
EP0155651B1 (fr) Procédé de filtration des liquides et le dispositif pour effectuer le procédé
DE69216579T2 (de) Verfahren und anlage zur filtrierung einer fluessigkeit, die suspendierte teilchen enthaelt
DE2725895A1 (de) Verfahren und vorrichtung zum behandeln eines fluids
CH433192A (de) Einrichtung zur Abscheidung und Fraktionierung von in einer Flüssigkeit gelöstem oder suspendiertem Material
DE2411828A1 (de) Verfahren zum adsorbieren von in einer waessrigen fluessigkeit enthaltenen fremdstoffen an koerniger aktivkohle

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A1

Designated state(s): JP US

AL Designated countries for regional patents

Kind code of ref document: A1

Designated state(s): AT BE CH DE DK ES FR GB IT LU NL SE