WO1991001884A1 - Impression laser a encre combinee sur des comprimes - Google Patents

Impression laser a encre combinee sur des comprimes Download PDF

Info

Publication number
WO1991001884A1
WO1991001884A1 PCT/US1990/004098 US9004098W WO9101884A1 WO 1991001884 A1 WO1991001884 A1 WO 1991001884A1 US 9004098 W US9004098 W US 9004098W WO 9101884 A1 WO9101884 A1 WO 9101884A1
Authority
WO
WIPO (PCT)
Prior art keywords
tablet
drum
location
tablets
ink
Prior art date
Application number
PCT/US1990/004098
Other languages
English (en)
Inventor
Chris R. Redford
Carl H. Sackman
Original Assignee
The Upjohn Company
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by The Upjohn Company filed Critical The Upjohn Company
Publication of WO1991001884A1 publication Critical patent/WO1991001884A1/fr

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A61J3/007—Marking tablets or the like
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B41—PRINTING; LINING MACHINES; TYPEWRITERS; STAMPS
    • B41F—PRINTING MACHINES OR PRESSES
    • B41F17/00—Printing apparatus or machines of special types or for particular purposes, not otherwise provided for
    • B41F17/36—Printing apparatus or machines of special types or for particular purposes, not otherwise provided for for printing on tablets, pills, or like small articles

Definitions

  • This invention relates to a process and apparatus for branding tablets, specifically pharmaceutical tablets, which process and apparatus preferably includes a feeder which initially moves individual tablets into a first station wherein an offset printing device prints a graphic symbol or geometric shape on an exposed face of the tablet, whereupon the feeder then moves the tablet to a second station whereat a laser marking system removes portions of the offset printed ink to expose the tablet coating therebeneath.
  • Tablets particularly pharmaceutical tablets, conventionally have trademarks (such as names or symbols) or company names printed thereon, such conventionally being referred to as "branding" of the tablets.
  • This printing on or "branding" of tablets is conventionally done by tablet printing machines which are based on conventional offset printing technologies. These machines pick up and retain tablets in machine cavities. A rubber print roll then picks up ink from an engraved “design” roll and places it on the tablets.
  • U.S. Patent No. 4 672 892 illustrates a conventional tablet printing apparatus wherein tablets within a hopper are positioned into recesses formed in a drum periphery, which recesses have suction applied thereto to hold the tablets therein. The tablets are then moved past a first ink printer to print on one side face of the tablets, whereupon the tablets are then transferred to a chain conveyor and moved under a second printer to print on the other side face of the tablets.
  • U.S. Patent No. 3 889 591 illustrates another known tablet printing arrangement similar to that of Ackley described above. More specifically, Noguchio supplies tablets from a hopper to drum recesses, with the tablets being positioned and held by a vacuum. The drum moves the tablets past a first ink printer which prints on one side of the tablets, and then transfer ' s the tablets to a second drum which moves them past a second ink printer which prints on the other side of the tablets.
  • TJ.S. Patent No. 4 619 196 discloses a tablet printer wherein tablets from a hopper are positioned in drum recesses which connect to a vacuum, with the tablets being moved past a conventional ink roller to print on one side of the tablet.
  • U.S. Patent No. 2 859 689 discloses a conventional arrangement wherein tablets are transferred from a hopper to recesses in a rotary drum, and are then transferred to a chain conveyor which moves the tablets under the ink-printing roller.
  • U.S. Patent No. 3 802 340 (Braum) illustrates a device which involves a rotary drum having recesses for the tablets, with ink rollers being disposed both inside and outside the drum to permit printing on both sides of the tablets.
  • U.S. Patent No. 3 106 166 (Sawtelle) discloses a device involving a sloped rotary table for feeding tablets past an ink roller.
  • U.S. Patent No. 4 254 704 illustrates a drum-type arrangement which feeds capsules to a secondary drum, the latter having a vacuum applied to the recesses for holding the capsules therein.
  • the second drum transfers the capsules to a standard chain conveyor which feeds the capsules under an ink-printing roller.
  • the tablets are not securely or precisely held within the machine cavities, and in fact are often free to move. Hence, this often results in the printing being inaccurately positioned on the tablet.
  • the print quality in conventional machines of the aforementioned types often is less than desired.
  • the rubber print roll that transfers the ink onto the tablet often becomes dirty, resulting in smudged lettering. When this occurs, the operator must stop the machine and clean the rubber roll.
  • the ink in the ink tray gradually gives up its solvents to the air over time, and the operator must periodically stop the machine to add solvent and stir the ink. This inconsistency in the viscosity of the ink can result in print that is smudged or print that is faded.
  • Another problem associated with some of the known machines is their inability to detect defective tablets. That is, these machines have no sorting system to keep broken or defective tablets out of the machine, and hence such tablets are passed through the machine and branded along with the good tablets. Further, since the tablets in some of the machine cavities are free to "float", a tablet will occasionally bounce out of the cavity, and such tablet can then be crushed by the print roll, thereby creating a contamination problem.
  • the present invention relates to an improved tablet branding process which is basically a two-step process in that the first step prints a graphic symbol or geometric shape on the tablets surface using traditional offset printing technology, whereas the second step employs a laser marking system to remove portions of the offset printed ink to thus expose the tablet coating therebeneath.
  • the areas of the tablet coating thus exposed form graphic symbols or alpha-numeric text within the offset printed area.
  • the present invention also relates to an improved branding process, as aforesaid, wherein the tablets are preferably fed from a hopper into a series of recesses which are formed circumferentially around a feed drum, which drum rotates the tablets initially through alignment stations which ensure that the tablets are properly seated within the drum cavities, then rotates the tablets past a printing station whereby a graphic symbol or geometric shape is ink printed onto the tablet surface.
  • the drum then rotates the tablets past a marking station whereby a laser acts through an appropriate mask to remove selected portions of the printed ink to thereby expose the underlying tablet coating which is of a significant color difference from the printed ink to thereby create a distinctive marking (such as a name or symbol) within the offset printed area.
  • the drum then rotates the tablets past an inspection station and past a reject station which ejects defective tablets from the drum, and then rotates the tablets to an ejection station for removal from the drum.
  • the present invention also relates to an improved machine or apparatus for branding of tablets according to the two-step process explained above.
  • the machine preferably includes a single rotatable drum having a series of cavities or recesses thereon, which cavities are preferably connected to a suction source so as to securely retain tablets within the individual cavities.
  • An ink-printing apparatus including an ink-printing roller, is disposed at a first station circumferentially around the drum to permit ink printing of a selected shape or symbol onto the tablet surface.
  • a conventional laser marking system is disposed at a second station adjacent the drum which is rotationally located downstream from the ink-printing device. This laser marking device effects selected removal of the ink printed area to hence form a symbol or lettering or numbers within the ink printed area.
  • Inspecting and tablet rejecting devices are located adjacent the drum periphery in the rotational downstream direction from the laser marking system.
  • the complete two- step printing or marking operation including feeding and discharging of tablets to and from the drum, can be accomplished on a single drum during a single rotation thereof.
  • Figure 1 is a schematic side elevational view illustrating a tablet branding machine of this invention.
  • Figure- 2 is an enlarged, fragmentary sectional view illustrating the perimeter of the drum and the tablet-receiving recesses therein.
  • Figures3 illustrates a tablet, with a brand thereon as fo ⁇ jied according to the invention.
  • FIG. 3 there is illustrated a sample tablet 10 which is branded using the two-step technique of the present invention.
  • This branding is applied to one of the faces 11 of the tablet and includes a graphic symbol or geometric shape 12 which is applied to this face 11 by means of ink printing, such as by a conventional offset printing technique.
  • This geometric shape or graphic symbol 12 in the illustrated embodiment, comprises an elongate rectangle of a solid color corresponding to the ink color. Further, the ink is of a color which is significantly different from the surface color of the tablet so as to create a significant visual difference or contrast.
  • portions of the ink coating defining the geometric shape 12 are removed, such as at the regions designated 13, so as to define a desired symbol and/or alphabetic and/or numeric characters.
  • These removed ink surface areas 13 in the illustrated embodiment define the trademark "MOTRIN".
  • These ink-removal areas 13 normally also slightly penetrate the surface of the tablet, but still retain an original tablet color to hence create a significant color difference and thus a significant visual contrast between the ink-removal areas 13 and the surrounding ink-defined geometric shape 12.
  • the brand of Figure 3 is solely for explanation purposes, and numerous variations can be made therein both with respect to the graphic symbol or geometric shape 12, and the ink-removal areas 13.
  • This apparatus includes a frame 21 which is indicated only generally by dotted lines, and on which a tablet feed drum 22 is supported for rotation about a generally horizontal axis.
  • This feed drum 22 defines in the outer perimeter or periphery thereof a series of circumferentially shaped small cavities 23 ( Figure 2) , each of which is adapted to at least partially accommodate a tablet 10 therein.
  • These cavities 23 are uniformly angularly spaced circumferentially around the drum so as to be disposed substantially within at least one circumferentially-extending row.
  • the drum 22 rotatably and sealingly cooperates with interior divider walls 24, 25 and 26 which are stationary and cooperate with the rotatable drum to define vacuum chambers 27 and 28 which cooperate with the drum over a selected arcuate extent thereof.
  • These vacuum chambers 27 and 28 communicate with a conventional vacuum source (not shown) such as a vacuum pump.
  • the chamber 27 is preferably maintained at a low vacuum, and the chamber 28 maintained at a higher vacuum, this being accomplished through suitable pressure-regulating controls.
  • the peripheral drum wall has small vacuum-communicating passages 29 extending radially therethrough for communication with the bottom of each of the cavities 10, which passages 29 communicate with the vacuum chambers 27 * and 28 when the respective recess 23 moves through this selective arcuate extent.
  • the feed drum 22 is supplied with conventional tablets at a first station, such supply in the illustrated embodiment being by means of a hopper 31 which communicates with the upper region of the drum 22 and has a lower discharge chute which is positioned so as to closely conform with the periphery of the drum to permit tablets to be deposited into the individual recesses 23.
  • a hopper 31 which communicates with the upper region of the drum 22 and has a lower discharge chute which is positioned so as to closely conform with the periphery of the drum to permit tablets to be deposited into the individual recesses 23.
  • suitable alignment brushes 32 or similar devices can be provided adjacent the periphery of the drum to assist in aligning and properly seating the tablets within the respective recesses.
  • the tablet-containing recesses then pass into the arcuate region encompassed by the vacuum chamber 27, which vacuum communicates with the tablet- containing recesses 23 through the openings 29 to assist in properly seating the tablets within the individual recesses.
  • any of the tablets do not properly seat, and hence are not properly sucked against the bottom of the recess, then as the drum moves downwardly, these tablets fall into a collecting chute 33 which directs them into a suitable collecting receptacle 34.
  • the tablets which are properly seated in the respective recesses are held firmly therein due to the suction applied through the opening 29, and hence remain seated even as the tablet moves downwardly around the lower periphery of the drum.
  • an ink-printing means 35 At a station or location disposed downstream from the chute 33, there is provided an ink-printing means 35, the latter being disposed directly adjacent the periphery of the drum adjacent the lower part thereof.
  • This ink-printing means comprises a generally conventional offset-type ink printer in that it includes an ink reservoir 36 for supplying ink onto a first roller 37, the latter being conventionally an engraved "design" roller. This roller 37 in turn transfer the ink to a rotatable rubber print roll 38.
  • This latter roller 38 is supported for rotation about an axis generally parallel with the drum rotation axis, and has its printing periphery disposed directly adjacent the periphery of the drum so as to permit a graphic symbol or geometric shape (such as shape 12 in Figure 3) to be printed on the exposed face of the tablet.
  • the ink-printing means 35 in the illustrated embodiment includes two print rolls 38 and 38' mounted on a turret which can be alternately rotated between two positions so that either ink roll 38 or 38' can be disposed in the print position, and the other disposed for engagement with a cleaning roll 39. It will be appreciated, however, that any conventional offset type printing roll arrangement, many of which are already conventional for printing of tablets,:can be utilized.
  • the drum 22 After leaving the location of the printing means 35, the drum 22 carries the tablets downstream to an adjacent location whereat there is provided a laser marking system 41.
  • This laser marking system 41 is disposed adjacent the periphery of the drum and cooperates in a conventional manner, such as through a suitable mask, for marking a tablet.
  • This laser marking system 41 is capable of effecting removal of selected portions of the previously printed ink area, such as portions 13 illustrated by Figure 3, to thereby create either a symbol or some other selected alphabetic and/or numeric designation.
  • the laser is preferably adjusted to also effect partial removal of a very small depth of the underlying coating or surface material of the tablet, whereby the removed areas hence provide a very sharp and distinct contrast to the surrounding inked areas.
  • this laser marking system 41 enables creation of very sharp, distinct and complex shapes or configurations or letters, and hence provides a capability which is not possible using conventional tablet ink-printing techniques.
  • the laser marking system itself is a known arrangement which has primarily been used for creating labels and -signs, and one example of such system is manufactured by Lumonics Marking Corporation.
  • the apparatus 20 also preferably includes a tablet inspection device 42 disposed adjaceiaft the periphery of the drum at a location downstream of the laser marking system 41.
  • the purpose of this inspection device 42 is to inspect the brand for accuracy, and to permit rejection of all defective tablets.
  • the inspection device 42 locates a defective tablet, then it transmits an appropriate signal to an air jet 43 which is located downstream thereof whereby, with suitable timing, the air jet 43 is activated to apply pressure to the underside of the recess to effectively dislodge the defective tablet, which defective tablet is collected in a receptacle 44.
  • the printing means 35 and the laser marking system 41 both cooperate with the arcuate region of the drum which extends over the high vacuum chamber 28 so that the tablets are hence securely retained within the respective recesses.
  • the remaining tablets are then rotatably carried by the drum out of the region which communicates with the high vacuum chamber 28, until the tablets are substantially aligned with a discharge chute 46.
  • An air ejecting nozzle 47 is disposed interiorly of the drum so as to dislodge the branded tablets from the respective recesses, whereby the tablets then drop downwardly along the chute 46 for deposit into a collecting receptacle 48.
  • the tablet feed device may comprise an endless belt having tablet-receiving recesses spaced therealong, whereby the belt hence defines an endless path havingrink printing and laser marking stations disposed at spaced intervals therealong.

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Medicinal Preparation (AREA)

Abstract

Procédé et appareil d'inscription de marques sur des comprimés, comprenant une unité d'alimentation (22) définissant une rangée d'évidements (23) chacun adapté pour recevoir un comprimé. Ladite unité d'alimentation déplace des comprimés individuels jusqu'à un premier poste où un dispositif d'impression offset (35) imprime un symbole à encre graphique ou une forme géométrique sur une face exposée du comprimé. Ladite unité d'alimentation déplace ensuite le comprimé jusqu'à un second poste où un système de marquage (41) à laser retire des parties de l'encre imprimée offset afin d'exposer la matière du comprimé se trouvant en-dessous.
PCT/US1990/004098 1989-07-27 1990-07-27 Impression laser a encre combinee sur des comprimes WO1991001884A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US38728089A 1989-07-27 1989-07-27
US387,280 1989-07-27

Publications (1)

Publication Number Publication Date
WO1991001884A1 true WO1991001884A1 (fr) 1991-02-21

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PCT/US1990/004098 WO1991001884A1 (fr) 1989-07-27 1990-07-27 Impression laser a encre combinee sur des comprimes

Country Status (3)

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AU (1) AU6079190A (fr)
CA (1) CA2057047A1 (fr)
WO (1) WO1991001884A1 (fr)

Cited By (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993013909A1 (fr) * 1992-01-14 1993-07-22 Alza Corporation Systeme de traitement au laser de comprimes avec double acces aux comprimes
US5492112A (en) * 1991-05-20 1996-02-20 Dura Pharmaceuticals, Inc. Dry powder inhaler
US5658474A (en) * 1994-12-16 1997-08-19 Alza Corporation Method and apparatus for forming dispenser delivery ports
WO1999056866A1 (fr) * 1998-05-01 1999-11-11 Central Research Laboratories Limited Appareil pour positionner plusieurs articles
EP1149572A1 (fr) * 2000-04-26 2001-10-31 Shin-Etsu Chemical Co., Ltd. Préparation solide comprenant un film d'enrobage à deux ou plusieurs couleurs
EP1167508A1 (fr) * 2000-06-27 2002-01-02 The Procter & Gamble Company Pastilles nettoyantes et procédé de manufacture
WO2001050877A3 (fr) * 2000-01-07 2002-02-07 Mars Inc Procede d'impression d'images multicolores sur des produits comestibles
US6429889B1 (en) * 1999-07-23 2002-08-06 Tri-Star Technologies Laser marking discrete consumable articles
US6677296B2 (en) 1999-12-16 2004-01-13 Unilever Home & Personal Care Usa Division Of Conopco, Inc. Washing tablets marked with indicia on their surfaces
US7029112B2 (en) 2002-08-05 2006-04-18 Mars, Incorporated Ink-jet printing on surface modified edibles and products made
US7102741B2 (en) 2002-11-13 2006-09-05 Ackley Machine Corporation Printing/inspection unit, method and apparatus for printing and/or inspecting and accepting/removing specified pellet-shaped articles from a conveyer mechanism
WO2009026103A1 (fr) * 2007-08-17 2009-02-26 Bpsi Holdings, Llc Procédé et agencement utilisés pour former des produits pharmaceutiques de couleur variable
AU2005239675B2 (en) * 2000-01-07 2009-03-12 Ackley Machine Corp Method to print multicolor images on edible pieces
RU2449771C2 (ru) * 2004-06-09 2012-05-10 Смитклайн Бичам Корпорейшн Устройство и способ фармацевтического производства
US8371216B2 (en) 2009-12-03 2013-02-12 Mars, Incorporated Conveying and marking apparatus and method
WO2013040599A2 (fr) 2011-09-16 2013-03-21 Tri-Star Technologies Système et procédé de marquage laser de capsules
US9101962B2 (en) 2010-06-01 2015-08-11 Ackley Machine Corporation Inspection system
JPWO2015186693A1 (ja) * 2014-06-02 2017-04-20 ニプロ株式会社 レーザー印刷用錠剤及びその製造方法
WO2017067685A1 (fr) * 2015-10-21 2017-04-27 Capsugel Belgium N.V. Procédé d'impression pour des formes pharmaceutiques orales
EP3427713A4 (fr) * 2016-03-07 2019-09-18 Freund Corporation Comprimé, dispositif d'impression sur comprimé et procédé d'impression sur comprimé

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6776340B2 (en) 1999-07-23 2004-08-17 Tri Star Technologies, A General Partnership Duplicate laser marking discrete consumable articles

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4672892A (en) * 1983-10-24 1987-06-16 Ackley E Michael Apparatus for conveying and marking pellet-shaped articles
US4707711A (en) * 1986-05-15 1987-11-17 Lumonics Inc. Character imaging system

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4672892A (en) * 1983-10-24 1987-06-16 Ackley E Michael Apparatus for conveying and marking pellet-shaped articles
US4707711A (en) * 1986-05-15 1987-11-17 Lumonics Inc. Character imaging system

Cited By (45)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5492112A (en) * 1991-05-20 1996-02-20 Dura Pharmaceuticals, Inc. Dry powder inhaler
WO1993013909A1 (fr) * 1992-01-14 1993-07-22 Alza Corporation Systeme de traitement au laser de comprimes avec double acces aux comprimes
US5294770A (en) * 1992-01-14 1994-03-15 Alza Corporation Laser tablet treatment system with dual access to tablet
US5658474A (en) * 1994-12-16 1997-08-19 Alza Corporation Method and apparatus for forming dispenser delivery ports
WO1999056866A1 (fr) * 1998-05-01 1999-11-11 Central Research Laboratories Limited Appareil pour positionner plusieurs articles
US6429889B1 (en) * 1999-07-23 2002-08-06 Tri-Star Technologies Laser marking discrete consumable articles
US6677296B2 (en) 1999-12-16 2004-01-13 Unilever Home & Personal Care Usa Division Of Conopco, Inc. Washing tablets marked with indicia on their surfaces
AU2009202320B2 (en) * 2000-01-07 2011-09-29 Ackley Machine Corp Edible Pieces with Printed Multicolour Images
US7311045B2 (en) 2000-01-07 2007-12-25 Ackley Machine Corp. Method for printing multicolor images on edible pieces
WO2001050877A3 (fr) * 2000-01-07 2002-02-07 Mars Inc Procede d'impression d'images multicolores sur des produits comestibles
EP1764002A3 (fr) * 2000-01-07 2007-10-31 Mars, Incorporated Procédé d'impression d'images multicolores sur des produits comestibles
AU2005239675B2 (en) * 2000-01-07 2009-03-12 Ackley Machine Corp Method to print multicolor images on edible pieces
AU2009202320B8 (en) * 2000-01-07 2011-11-10 Ackley Machine Corp Edible Pieces with Printed Multicolour Images
US7114445B2 (en) 2000-01-07 2006-10-03 Ackley Machine Corp. Method to print multicolor images on edible pieces
US7182018B2 (en) 2000-01-07 2007-02-27 Mars Incorporated Apparatus for printing multicolor images on edible pieces
EP1149572A1 (fr) * 2000-04-26 2001-10-31 Shin-Etsu Chemical Co., Ltd. Préparation solide comprenant un film d'enrobage à deux ou plusieurs couleurs
KR100721088B1 (ko) * 2000-04-26 2007-05-23 신에쓰 가가꾸 고교 가부시끼가이샤 필름 코팅층으로 피복된 고형제제 및 필름 코팅제
US8021690B2 (en) 2000-04-26 2011-09-20 Shin-Etsu Chemical Co., Ltd. Solid preparation coated with a film coating layer and film coating agent
WO2002000818A1 (fr) * 2000-06-27 2002-01-03 The Procter & Gamble Company Pastilles de nettoyage et procede de fabrication correspondant
EP1167508A1 (fr) * 2000-06-27 2002-01-02 The Procter & Gamble Company Pastilles nettoyantes et procédé de manufacture
US7029112B2 (en) 2002-08-05 2006-04-18 Mars, Incorporated Ink-jet printing on surface modified edibles and products made
US7500744B2 (en) 2002-08-05 2009-03-10 Mars, Incorprated Ink-jet printing on surface modified edibles and products made
US7102741B2 (en) 2002-11-13 2006-09-05 Ackley Machine Corporation Printing/inspection unit, method and apparatus for printing and/or inspecting and accepting/removing specified pellet-shaped articles from a conveyer mechanism
RU2449771C2 (ru) * 2004-06-09 2012-05-10 Смитклайн Бичам Корпорейшн Устройство и способ фармацевтического производства
WO2009026103A1 (fr) * 2007-08-17 2009-02-26 Bpsi Holdings, Llc Procédé et agencement utilisés pour former des produits pharmaceutiques de couleur variable
US8371216B2 (en) 2009-12-03 2013-02-12 Mars, Incorporated Conveying and marking apparatus and method
US10919076B2 (en) 2010-06-01 2021-02-16 Ackley Machine Corporation Inspection system
US9757772B2 (en) 2010-06-01 2017-09-12 Ackley Machine Corporation Inspection system
US10518294B2 (en) 2010-06-01 2019-12-31 Ackley Machine Corporation Inspection system
US9101962B2 (en) 2010-06-01 2015-08-11 Ackley Machine Corporation Inspection system
US10201837B2 (en) 2010-06-01 2019-02-12 Ackley Machine Corporation Inspection system
US9259766B2 (en) 2010-06-01 2016-02-16 Ackley Machine Corporation Inspection system
US9468948B2 (en) 2010-06-01 2016-10-18 Ackley Machine Corporation Inspection system
US11897001B2 (en) 2010-06-01 2024-02-13 Ackley Machine Corporation Inspection system
US9517855B2 (en) 2011-09-16 2016-12-13 Tri-Star Technologies Laser capsule marking system and method
US20170081069A1 (en) * 2011-09-16 2017-03-23 Tri-Star Technologies Laser Capsule Marking System and Method
EP2755826A4 (fr) * 2011-09-16 2016-01-13 Tri Star Technologies Système et procédé de marquage laser de capsules
US10492994B2 (en) 2011-09-16 2019-12-03 Tri-Star Technologies Laser capsule marking system and method
JP2014534903A (ja) * 2011-09-16 2014-12-25 トライスター テクノロジーズＴｒｉｓｔａｒ Ｔｅｃｈｎｏｌｏｇｉｅｓ レーザカプセルマーキングシステムおよび方法
WO2013040599A3 (fr) * 2011-09-16 2013-05-10 Tri-Star Technologies Système et procédé de marquage laser de capsules
WO2013040599A2 (fr) 2011-09-16 2013-03-21 Tri-Star Technologies Système et procédé de marquage laser de capsules
JPWO2015186693A1 (ja) * 2014-06-02 2017-04-20 ニプロ株式会社 レーザー印刷用錠剤及びその製造方法
WO2017067685A1 (fr) * 2015-10-21 2017-04-27 Capsugel Belgium N.V. Procédé d'impression pour des formes pharmaceutiques orales
US10661301B2 (en) 2015-10-21 2020-05-26 Capsugel Belgium Nv Printing process for oral dosage forms
EP3427713A4 (fr) * 2016-03-07 2019-09-18 Freund Corporation Comprimé, dispositif d'impression sur comprimé et procédé d'impression sur comprimé

Also Published As

Publication number Publication date
CA2057047A1 (fr) 1991-01-28
AU6079190A (en) 1991-03-11

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