WO1990011688A1 - Avirulent microbes and uses therefor - Google Patents
Avirulent microbes and uses therefor Download PDFInfo
- Publication number
- WO1990011688A1 WO1990011688A1 PCT/US1990/001603 US9001603W WO9011688A1 WO 1990011688 A1 WO1990011688 A1 WO 1990011688A1 US 9001603 W US9001603 W US 9001603W WO 9011688 A1 WO9011688 A1 WO 9011688A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- choleraesuis
- crp
- gene
- avirulent
- strain
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/025—Enterobacteriales, e.g. Enterobacter
- A61K39/0275—Salmonella
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
- C12N1/205—Bacterial isolates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
- C12R2001/42—Salmonella
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Definitions
- S. choleraesuis strains used in this Example are listed in Table 1. Bacterial strains were grown at 37°C in L broth and on L agar (Lennox, Virology 1: 190-206
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Wood Science & Technology (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Pharmacology & Pharmacy (AREA)
- Physics & Mathematics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Plant Pathology (AREA)
- Biophysics (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Immunology (AREA)
- Mycology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Tropical Medicine & Parasitology (AREA)
- Virology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Electronic Switches (AREA)
- Amplifiers (AREA)
- Stereophonic System (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US332,285 | 1981-12-18 | ||
US33228589A | 1989-03-31 | 1989-03-31 |
Publications (1)
Publication Number | Publication Date |
---|---|
WO1990011688A1 true WO1990011688A1 (en) | 1990-10-18 |
Family
ID=23297569
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US1990/001603 WO1990011688A1 (en) | 1989-03-31 | 1990-03-26 | Avirulent microbes and uses therefor |
Country Status (6)
Country | Link |
---|---|
EP (1) | EP0465561A4 (de) |
JP (1) | JPH04506000A (de) |
CN (1) | CN1046463A (de) |
AU (1) | AU5355990A (de) |
CA (1) | CA2013572A1 (de) |
WO (1) | WO1990011688A1 (de) |
Cited By (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1992019720A1 (fr) * | 1991-05-02 | 1992-11-12 | Institut Pasteur | Souches recombinantes immunogenes de b. anthracis - compositions immunogenes les contenant |
US5840312A (en) * | 1991-05-02 | 1998-11-24 | Institut Pasteur | Recombinant Bacillus anthracis strains unable to produce the lethal factor protein or edema factor protein |
US5922583A (en) * | 1995-10-17 | 1999-07-13 | Biostar Inc. | Methods for production of recombinant plasmids |
US8445254B2 (en) | 2007-05-10 | 2013-05-21 | The Arizona Board Of Regents For And On Behalf Of Arizona State University | Regulated expression of antigen and/or regulated attentuation to enhance vaccine immunogenicity and/or safety |
US8465755B2 (en) | 2007-10-05 | 2013-06-18 | The Arizona Board Of Regents For And On Behalf Of Arizona State University | Recombinant bacterium capable of eliciting an immune response against enteric pathogens |
US8889121B2 (en) | 2010-01-22 | 2014-11-18 | The Arizona Board Of Regents For An On Behalf Of Arizona State University | Bacterium comprising a regulated rfaH nucleic acid |
US9045742B2 (en) | 2009-05-29 | 2015-06-02 | The Arizona Board Of Regents For And On Behalf Of Arizona State University | Recombinant Edwardsiella bacterium |
US9050285B2 (en) | 2008-10-17 | 2015-06-09 | The United States of America National Institutes of Health (NH), U.S. Dept. of Health and Human Services (DHHS) | Recombinant bacterium capable of eliciting an immune response against Streptococcus pneumoniae |
US9062297B2 (en) | 2010-01-13 | 2015-06-23 | The Arizona Board Of Regents For And On Behalf Of Arizona State University | Yersinia pestis vaccine |
US9163219B2 (en) | 2009-04-14 | 2015-10-20 | Arizona Board Of Regents On Behalf Of Arizona State University | Single expression vector for generation of a virus with a segmented genome |
US9303264B2 (en) | 2012-05-18 | 2016-04-05 | The Arizona Board Of Regents For And On Behalf Of Arizona State University | Photosynthetic microorganisms expressing thermostable lipase |
US9481888B2 (en) | 2009-05-22 | 2016-11-01 | The Arizona Board Of Regents For And On Behalf Of Arizona State University | Recombinant bacterium and methods of antigen and nucleic acid delivery |
US9580718B2 (en) | 2013-06-17 | 2017-02-28 | Arizona Board Of Regents On Behalf Of Arizona State University | Attenuated live bacteria with increased acid resistance and methods of use thereof |
US9598697B2 (en) | 2010-05-28 | 2017-03-21 | The Arizona Board Of Regents For And On Behalf Of Arizona State University | Recombinant bacterium to decrease tumor growth |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2194837T3 (es) * | 1990-11-09 | 2003-12-01 | Univ Washington | Microbios de salmonella avirulentos que comprenden una mutacion en el gen cdt y usos de los mismos. |
US6713073B1 (en) * | 1998-07-24 | 2004-03-30 | Megan Health, Inc. | Method of vaccination of newly hatched poultry |
-
1990
- 1990-03-26 EP EP19900905860 patent/EP0465561A4/en not_active Withdrawn
- 1990-03-26 AU AU53559/90A patent/AU5355990A/en not_active Abandoned
- 1990-03-26 WO PCT/US1990/001603 patent/WO1990011688A1/en not_active Application Discontinuation
- 1990-03-26 JP JP2505540A patent/JPH04506000A/ja active Pending
- 1990-03-30 CA CA002013572A patent/CA2013572A1/en not_active Abandoned
- 1990-03-31 CN CN90102664A patent/CN1046463A/zh active Pending
Non-Patent Citations (6)
Title |
---|
Immunological Investigations, Volume 18, pages 583-596. April 1989. R. CURTISS et al. Recombinant Avirulent Salmonella Vaccine Strains with stable maintenance and high level expression of cloned genes in vivo. See Abstract. * |
Infection and Immunity, Volume 55(12), pages 3035-3043. R. CURTISS et al. December 1987. Salmonella typhimurium Deletion Mutants Lacking Adenylate Cyclase and Cyclic AMP Receptor Protein are Avirulent and Immunogenic. See Abstract. * |
Infection and Immunity, Volume 55(4), pages 955-962. N.A. NNALUE et al. April 1987. "Tests of the Virulence and Live-Vaccine Efficacy of Auxotrophic and gal E Derivatives of Salmonella choleraesuis. See Abstract. * |
Japan Journal of Veternary Science, Volume 50, pages 706-713. July 1988. N'AKAMURA, et al. Virulence and Immunogenicity of Plasimid-cured Salmonella serovar Enteritidis AL1192 against Cattle. See Abstract. * |
Microbial Pathogenesis, Volume 7, pages 299-310. December 1989. N.A. NNALUE et al. Vaccination Route, infectivity and thioglycollate broth administration: effects on live vaccine efficacy of auxotrophic derivatives of Salmonella Choleraesuis. See Abstract. * |
See also references of EP0465561A4 * |
Cited By (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5840312A (en) * | 1991-05-02 | 1998-11-24 | Institut Pasteur | Recombinant Bacillus anthracis strains unable to produce the lethal factor protein or edema factor protein |
WO1992019720A1 (fr) * | 1991-05-02 | 1992-11-12 | Institut Pasteur | Souches recombinantes immunogenes de b. anthracis - compositions immunogenes les contenant |
US5922583A (en) * | 1995-10-17 | 1999-07-13 | Biostar Inc. | Methods for production of recombinant plasmids |
US9297015B2 (en) | 2007-05-10 | 2016-03-29 | Arizona Board Of Regents For And On Behalf Of Arizona State University | Regulated expression of antigen and/or regulated attentuation to enhance vaccine immunogenicity and/or safety |
US8445254B2 (en) | 2007-05-10 | 2013-05-21 | The Arizona Board Of Regents For And On Behalf Of Arizona State University | Regulated expression of antigen and/or regulated attentuation to enhance vaccine immunogenicity and/or safety |
US11920139B2 (en) | 2007-05-10 | 2024-03-05 | The Washington University | Regulated expression of antigen and/or regulated attenuation to enhance vaccine immunogenicity and/or safety |
US11180765B2 (en) | 2007-05-10 | 2021-11-23 | The Arizona Board Of Regents For And On Behalf Of Arizona State University | Regulated expression of antigen and/or regulated attenuation to enhance vaccine immunogenicity and/or safety |
US10774334B2 (en) | 2007-05-10 | 2020-09-15 | Arizona Broad of Regents on Behalf of Arizona State University | Regulated expression of antigen and/or regulated attenuation to enhance vaccine immunogenicity and/or safety |
US8465755B2 (en) | 2007-10-05 | 2013-06-18 | The Arizona Board Of Regents For And On Behalf Of Arizona State University | Recombinant bacterium capable of eliciting an immune response against enteric pathogens |
US9040059B2 (en) | 2007-10-05 | 2015-05-26 | The Arizona Board Of Regents For And On Behalf Of Arizona State University | Recombinant bacterium capable of eliciting a protective immune response against C. perfringens |
US9050285B2 (en) | 2008-10-17 | 2015-06-09 | The United States of America National Institutes of Health (NH), U.S. Dept. of Health and Human Services (DHHS) | Recombinant bacterium capable of eliciting an immune response against Streptococcus pneumoniae |
US9163219B2 (en) | 2009-04-14 | 2015-10-20 | Arizona Board Of Regents On Behalf Of Arizona State University | Single expression vector for generation of a virus with a segmented genome |
US9481888B2 (en) | 2009-05-22 | 2016-11-01 | The Arizona Board Of Regents For And On Behalf Of Arizona State University | Recombinant bacterium and methods of antigen and nucleic acid delivery |
US9045742B2 (en) | 2009-05-29 | 2015-06-02 | The Arizona Board Of Regents For And On Behalf Of Arizona State University | Recombinant Edwardsiella bacterium |
US9062297B2 (en) | 2010-01-13 | 2015-06-23 | The Arizona Board Of Regents For And On Behalf Of Arizona State University | Yersinia pestis vaccine |
US8889121B2 (en) | 2010-01-22 | 2014-11-18 | The Arizona Board Of Regents For An On Behalf Of Arizona State University | Bacterium comprising a regulated rfaH nucleic acid |
US9598697B2 (en) | 2010-05-28 | 2017-03-21 | The Arizona Board Of Regents For And On Behalf Of Arizona State University | Recombinant bacterium to decrease tumor growth |
US9303264B2 (en) | 2012-05-18 | 2016-04-05 | The Arizona Board Of Regents For And On Behalf Of Arizona State University | Photosynthetic microorganisms expressing thermostable lipase |
US9580718B2 (en) | 2013-06-17 | 2017-02-28 | Arizona Board Of Regents On Behalf Of Arizona State University | Attenuated live bacteria with increased acid resistance and methods of use thereof |
Also Published As
Publication number | Publication date |
---|---|
JPH04506000A (ja) | 1992-10-22 |
CA2013572A1 (en) | 1990-09-30 |
CN1046463A (zh) | 1990-10-31 |
AU5355990A (en) | 1990-11-05 |
EP0465561A4 (en) | 1992-04-08 |
EP0465561A1 (de) | 1992-01-15 |
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