WO1990006307A3 - Composes de quinolone antibacteriens - Google Patents

Composes de quinolone antibacteriens

Info

Publication number
WO1990006307A3
WO1990006307A3 PCT/US1989/005213 US8905213W WO9006307A3 WO 1990006307 A3 WO1990006307 A3 WO 1990006307A3 US 8905213 W US8905213 W US 8905213W WO 9006307 A3 WO9006307 A3 WO 9006307A3
Authority
WO
WIPO (PCT)
Prior art keywords
quinolone compounds
antibacterial quinolone
antibacterial
compound
compounds
Prior art date
Application number
PCT/US1989/005213
Other languages
English (en)
Other versions
WO1990006307A2 (fr
Inventor
Ronald B Gammill
Sharon N Bisaha
Joseph M Timko
Thomas M Judge
Michael R Barbachyn
Kyoung S Kim
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Priority to KR1019900701694A priority Critical patent/KR910700243A/ko
Publication of WO1990006307A2 publication Critical patent/WO1990006307A2/fr
Publication of WO1990006307A3 publication Critical patent/WO1990006307A3/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
    • C07D215/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

On décrit un composé de quinolone ayant la formule (I) et présentant des propriétés antibactériennes, des compositions pharmaceutiques contenant ledit composé de quinolone, ainsi qu'un procédé permettant de traiter des infections d'origine bactérienne chez les animaux, y compris les humains.
PCT/US1989/005213 1988-12-06 1989-11-24 Composes de quinolone antibacteriens WO1990006307A2 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
KR1019900701694A KR910700243A (ko) 1988-12-06 1989-11-24 향균성 퀴놀론 화합물

Applications Claiming Priority (10)

Application Number Priority Date Filing Date Title
US28060388A 1988-12-06 1988-12-06
US280,603 1988-12-06
US32690789A 1989-03-22 1989-03-22
US326,907 1989-03-22
US33516389A 1989-04-07 1989-04-07
US335,163 1989-04-07
US35501689A 1989-05-22 1989-05-22
US355,016 1989-05-22
US41144989A 1989-09-25 1989-09-25
US411,449 1989-09-25

Publications (2)

Publication Number Publication Date
WO1990006307A2 WO1990006307A2 (fr) 1990-06-14
WO1990006307A3 true WO1990006307A3 (fr) 1990-07-26

Family

ID=27540650

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1989/005213 WO1990006307A2 (fr) 1988-12-06 1989-11-24 Composes de quinolone antibacteriens

Country Status (5)

Country Link
EP (1) EP0447484A1 (fr)
JP (1) JPH04502317A (fr)
AU (1) AU4743890A (fr)
CA (1) CA2004693A1 (fr)
WO (1) WO1990006307A2 (fr)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5137892A (en) * 1990-12-12 1992-08-11 Abbott Laboratories Quinoline, naphthyridine and pyridobenzoxazine derivatives
ES2036136B1 (es) * 1991-10-16 1994-03-01 Inke Sa Procedimiento para la obtencion del acido 1-(2,4-difluorofenil)-6-fluoro-7-(3-metilpiperacinil)-4-oxo-1, 4-dihidroquinolin-3-carboxilico y sus sales.
WO1994025464A1 (fr) * 1993-04-24 1994-11-10 Korea Research Institute Of Chemical Technology Nouveaux derives d'acide quinolone-carboxylique et leur procede de preparation
KR950018003A (ko) * 1993-12-09 1995-07-22 스미스클라인 비참 피엘씨 신규한 퀴놀론 유도체 및 그의 제조 방법
WO2002018345A1 (fr) * 2000-08-29 2002-03-07 Chiron Corporation Composes de quinoline antibacteriens et procedes d'utilisation de ceux-ci
US8163769B2 (en) 2002-03-12 2012-04-24 Abbott Laboratories Antibacterial compounds
MXPA05009688A (es) * 2003-03-12 2005-12-05 Abbott Lab Derivados de naftiridina como agentes antibacterianos.
US9447026B2 (en) 2013-03-14 2016-09-20 Kalyra Pharmaceuticals, Inc. Bicyclic analgesic compounds
WO2015089170A1 (fr) 2013-12-12 2015-06-18 Kalyra Pharmaceuticals, Inc. Composés d'alkyle bicyclique et synthèse
CN113336653A (zh) 2014-03-07 2021-09-03 里科瑞尔姆Ip控股有限责任公司 螺桨烷衍生物及合成
CA2961605C (fr) 2014-09-17 2023-01-10 Kalyra Pharmaceuticals, Inc. Composes bicycliques

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4559342A (en) * 1983-02-25 1985-12-17 Bayer Aktiengesellschaft Quinolone acids and antibacterial agents containing these compounds
US4563448A (en) * 1983-03-12 1986-01-07 Bayer Aktiengesellschaft Bactericidal agents

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0811749B2 (ja) * 1986-03-06 1996-02-07 富山化学工業株式会社 新規なキノリン誘導体およびその塩

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4559342A (en) * 1983-02-25 1985-12-17 Bayer Aktiengesellschaft Quinolone acids and antibacterial agents containing these compounds
US4563448A (en) * 1983-03-12 1986-01-07 Bayer Aktiengesellschaft Bactericidal agents

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Chemical Abstracts, Vol. 108, No. 15, 11 April 1988, Columbus, Ohio, US; Narita, Hirokazu et al.: "Preparation of quinolone carboxylic acid derivatives as medical bactericides", abstract 131600s, & JP,A,62 207 258 (11-09-87) *

Also Published As

Publication number Publication date
WO1990006307A2 (fr) 1990-06-14
AU4743890A (en) 1990-06-26
EP0447484A1 (fr) 1991-09-25
JPH04502317A (ja) 1992-04-23
CA2004693A1 (fr) 1990-06-06

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