CA2004693A1 - Composes de quinolone antibacteriens - Google Patents

Composes de quinolone antibacteriens

Info

Publication number
CA2004693A1
CA2004693A1 CA 2004693 CA2004693A CA2004693A1 CA 2004693 A1 CA2004693 A1 CA 2004693A1 CA 2004693 CA2004693 CA 2004693 CA 2004693 A CA2004693 A CA 2004693A CA 2004693 A1 CA2004693 A1 CA 2004693A1
Authority
CA
Canada
Prior art keywords
oxo
dihydro
fluoro
bicyclo
pent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA 2004693
Other languages
English (en)
Inventor
Sharon N. Bisaha
Joseph M. Timko
Thomas M. Judge
Michael R. Barbachyn
Kyoung S. Kim
Ronald B. Gammill
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pharmacia and Upjohn Co
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of CA2004693A1 publication Critical patent/CA2004693A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
    • C07D215/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
CA 2004693 1988-12-06 1989-12-06 Composes de quinolone antibacteriens Abandoned CA2004693A1 (fr)

Applications Claiming Priority (10)

Application Number Priority Date Filing Date Title
US28060388A 1988-12-06 1988-12-06
US07/280,603 1988-12-06
US32690789A 1989-03-22 1989-03-22
US07/326,907 1989-03-22
US33516389A 1989-04-07 1989-04-07
US07/335,163 1989-04-07
US35501689A 1989-05-22 1989-05-22
US07/355,016 1989-05-22
US41144989A 1989-09-25 1989-09-25
US07/411,449 1989-09-25

Publications (1)

Publication Number Publication Date
CA2004693A1 true CA2004693A1 (fr) 1990-06-06

Family

ID=27540650

Family Applications (1)

Application Number Title Priority Date Filing Date
CA 2004693 Abandoned CA2004693A1 (fr) 1988-12-06 1989-12-06 Composes de quinolone antibacteriens

Country Status (5)

Country Link
EP (1) EP0447484A1 (fr)
JP (1) JPH04502317A (fr)
AU (1) AU4743890A (fr)
CA (1) CA2004693A1 (fr)
WO (1) WO1990006307A2 (fr)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5137892A (en) * 1990-12-12 1992-08-11 Abbott Laboratories Quinoline, naphthyridine and pyridobenzoxazine derivatives
ES2036136B1 (es) * 1991-10-16 1994-03-01 Inke Sa Procedimiento para la obtencion del acido 1-(2,4-difluorofenil)-6-fluoro-7-(3-metilpiperacinil)-4-oxo-1, 4-dihidroquinolin-3-carboxilico y sus sales.
WO1994025464A1 (fr) * 1993-04-24 1994-11-10 Korea Research Institute Of Chemical Technology Nouveaux derives d'acide quinolone-carboxylique et leur procede de preparation
KR950018003A (ko) * 1993-12-09 1995-07-22 스미스클라인 비참 피엘씨 신규한 퀴놀론 유도체 및 그의 제조 방법
WO2002018345A1 (fr) * 2000-08-29 2002-03-07 Chiron Corporation Composes de quinoline antibacteriens et procedes d'utilisation de ceux-ci
US8163769B2 (en) 2002-03-12 2012-04-24 Abbott Laboratories Antibacterial compounds
JP2006514964A (ja) * 2003-03-12 2006-05-18 アボット・ラボラトリーズ 抗菌剤としてのナフチリジン誘導体
US9447025B2 (en) 2013-03-14 2016-09-20 Kalyra Pharmaceuticals, Inc. Bicyclic analgesic compounds
CN105814013A (zh) 2013-12-12 2016-07-27 卡利拉制药公司 双环烷基化合物及合成
JP6741343B2 (ja) * 2014-03-07 2020-08-19 リキュリウム アイピー ホールディングス リミテッド ライアビリティー カンパニー プロペラン誘導体および合成
JP6833677B2 (ja) 2014-09-17 2021-02-24 リキュリウム アイピー ホールディングス リミテッド ライアビリティー カンパニー 二環式化合物

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3306772A1 (de) * 1983-02-25 1984-08-30 Bayer Ag, 5090 Leverkusen Chinolonsaeuren, verfahren zu ihrer herstellung sowie diese enthaltende antibakterielle mittel
DE3308908A1 (de) * 1983-03-12 1984-09-13 Bayer Ag, 5090 Leverkusen Bakterizide mittel
JPH0811749B2 (ja) * 1986-03-06 1996-02-07 富山化学工業株式会社 新規なキノリン誘導体およびその塩

Also Published As

Publication number Publication date
JPH04502317A (ja) 1992-04-23
WO1990006307A2 (fr) 1990-06-14
WO1990006307A3 (fr) 1990-07-26
EP0447484A1 (fr) 1991-09-25
AU4743890A (en) 1990-06-26

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Legal Events

Date Code Title Description
EEER Examination request
FZDE Dead