WO1989010934A1 - Procalcitonin peptides - Google Patents

Procalcitonin peptides Download PDF

Info

Publication number
WO1989010934A1
WO1989010934A1 PCT/US1989/001856 US8901856W WO8910934A1 WO 1989010934 A1 WO1989010934 A1 WO 1989010934A1 US 8901856 W US8901856 W US 8901856W WO 8910934 A1 WO8910934 A1 WO 8910934A1
Authority
WO
WIPO (PCT)
Prior art keywords
peptide
proct
peptides
promoter
cells
Prior art date
Application number
PCT/US1989/001856
Other languages
English (en)
French (fr)
Inventor
Bernard A. Roos
Douglas M. Burns
Howard A. Guy
Gary L. Mcknight
Original Assignee
Zymogenetics, Inc.
The Board Of Regents Of The University Of Washingt
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zymogenetics, Inc., The Board Of Regents Of The University Of Washingt filed Critical Zymogenetics, Inc.
Publication of WO1989010934A1 publication Critical patent/WO1989010934A1/en
Priority to KR1019890702515A priority Critical patent/KR900700504A/ko
Priority to DK261990A priority patent/DK261990A/da
Priority to FI905453A priority patent/FI905453A0/fi
Priority to NO90904769A priority patent/NO904769L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/585—Calcitonins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Hematology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Endocrinology (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Nutrition Science (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
PCT/US1989/001856 1988-05-03 1989-05-02 Procalcitonin peptides WO1989010934A1 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
KR1019890702515A KR900700504A (ko) 1988-05-03 1989-12-30 프로칼시토닌 펩타이드
DK261990A DK261990A (da) 1988-05-03 1990-10-31 Procalcitoninpeptider
FI905453A FI905453A0 (fi) 1988-05-03 1990-11-02 Prokalcitoninpeptider.
NO90904769A NO904769L (no) 1988-05-03 1990-11-02 Procalcitoninpeptider.

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US270,137 1981-06-03
US295,719 1981-08-24
US18991388A 1988-05-03 1988-05-03
US189,913 1988-05-03
US27013788A 1988-11-14 1988-11-14
US29571989A 1989-01-10 1989-01-10

Publications (1)

Publication Number Publication Date
WO1989010934A1 true WO1989010934A1 (en) 1989-11-16

Family

ID=27392651

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1989/001856 WO1989010934A1 (en) 1988-05-03 1989-05-02 Procalcitonin peptides

Country Status (7)

Country Link
EP (1) EP0416029A1 (de)
JP (1) JPH03505327A (de)
KR (1) KR900700504A (de)
AU (1) AU3754889A (de)
DK (1) DK261990A (de)
FI (1) FI905453A0 (de)
WO (1) WO1989010934A1 (de)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH07505064A (ja) * 1991-12-18 1995-06-08 アイシーユー　メディカル、インコーポレイテッド 医療用弁
US5693615A (en) * 1991-06-05 1997-12-02 The Procter & Gamble Company Therapeutic compositions for osteoinduction
US5962270A (en) * 1996-02-06 1999-10-05 Bionebraska, Inc. Recombinant preparation of calcitonin fragments and use thereof in the preparation of calcitonin and related analogs
WO2003093314A2 (en) * 2002-05-03 2003-11-13 Millenium Biologix Inc. Connective tissue stimulating peptides
CN114478745A (zh) * 2022-03-30 2022-05-13 南京京达生物技术有限公司 一种重组降钙素原pct的分离纯化方法

Non-Patent Citations (7)

* Cited by examiner, † Cited by third party
Title
BIOLOGICAL ABSTRACTS, Vol. 88, No. 167369, D.M. BURNS et al., "A Novel Amino-terminal ***Procalcitonin*** -derived Neuroendocrine Peptide is Found in Rat Thyroid and Medullary Thyroid Carcinoma Tissues"; & CLIN. RES., 36(1), 1988, 150A. *
BIOLOGICAL ABSTRACTS, Vol. 88, No. 277550, D.M. BURNS et al., "An Amino-terminal ***Procalcitonin*** -derived Peptide Stimulates Osteoblast Proliferation In-Vitro"; & FASEB, (FED. AM. SOC. EXP. BIOL.), J 2(5), 1988, Abstract 4949. *
BIOLOGICAL ABSTRACTS, Vol. 89, No. 239440, D.M. BURNS et al., "Mitogenic Activity of Native and Recombinant Amino-terminal ***Procalcitonin*** Peptide on Osteoblasts"; & CLIN. RES., 37(1), 1989, 127A. *
FEBS LETTERS, Vol. 226, No. 1, December 1987, ELSEVIER SCIENCE PUBLISHERS B.V., (Biomedical Division), E. POESCHL et al., "The Structure of Procalcitonin of the Salmon as Deduced from Its cDNA Sequence", pages 96-100. *
MOLECULAR ENDOCRINOLOGY, Vol. 3, No. 1, 1989, THE ENDOCRINE SOCIETY, D.M. BURNS et al., "A Neuroendocrine Peptide Derived from the Amino-terminal Half of Rat Procalcitonin", pages 140-147. *
NATURE, Vol. 298, 15 July 1982, MACMILLAN JOURNALS LTD., S.G. AMARA et al., "Alternative RNA Processing in Calcitonin Gene Expression Generates mRNAs Encoding Different Polypeptide Products", pages 240-244. *
THE BIOCHEMICAL JOURNAL, Vol. 256, No. 1, 15 November 1988, THE BIOCHEMICAL SOCIETY, (London, GB), J.M. CONLON et al., "Structural Characterization of a High-molecular-mass Form of Calcitonin ÄProcalcitonin-(60-116)-peptideÜ and Its Corresponding N-terminal Flanking Peptide ÄProcalcitonin-(1-57)-peptideÜ in a Human Medullary Thyroid Carcinoma", pages 245-250. *

Cited By (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5693615A (en) * 1991-06-05 1997-12-02 The Procter & Gamble Company Therapeutic compositions for osteoinduction
JPH07505064A (ja) * 1991-12-18 1995-06-08 アイシーユー　メディカル、インコーポレイテッド 医療用弁
US5962270A (en) * 1996-02-06 1999-10-05 Bionebraska, Inc. Recombinant preparation of calcitonin fragments and use thereof in the preparation of calcitonin and related analogs
US6251635B1 (en) 1996-02-06 2001-06-26 Bionebraska, Inc. Recombinant preparation of calcitonin fragments and use thereof in the preparation of calcitonin and related analogs
US6410707B2 (en) 1996-02-06 2002-06-25 Bionebraska, Inc. Recombinant preparation of calcitonin fragments and use thereof in the preparation of calcitonin and related analogs
WO2003093314A2 (en) * 2002-05-03 2003-11-13 Millenium Biologix Inc. Connective tissue stimulating peptides
WO2003093314A3 (en) * 2002-05-03 2004-03-25 Millenium Biologix Inc Connective tissue stimulating peptides
US9133236B2 (en) 2002-05-03 2015-09-15 Dennis R. Sindrey Connective tissue stimulating peptides
US10202419B2 (en) 2002-05-03 2019-02-12 Octane Orthobiologics Inc. Connective tissue stimulating peptides
US11384117B2 (en) 2002-05-03 2022-07-12 Octane Orthobiologics Inc. Connective tissue stimulating peptides
CN114478745A (zh) * 2022-03-30 2022-05-13 南京京达生物技术有限公司 一种重组降钙素原pct的分离纯化方法
CN114478745B (zh) * 2022-03-30 2023-12-15 南京京达生物技术有限公司 一种重组降钙素原pct的分离纯化方法

Also Published As

Publication number Publication date
JPH03505327A (ja) 1991-11-21
AU3754889A (en) 1989-11-29
DK261990A (da) 1991-01-03
DK261990D0 (da) 1990-10-31
EP0416029A1 (de) 1991-03-13
KR900700504A (ko) 1990-08-13
FI905453A0 (fi) 1990-11-02

Similar Documents

Publication Publication Date Title
US5128321A (en) PDGF analogs and methods of use
US5827734A (en) Materials and methods for determining ob protein in a biological sample
US5059528A (en) Expression of human proapolipoprotein a-i
US5352770A (en) Porcine derived novel physiologically active peptide
Sugiyama et al. Synthesis of atrial natriuretic peptides and studies on structural factors in tissue specificity
BINOUX et al. Evidence for production by the liver of two IGF binding proteins with similar molecular weights but different affinities for IGF I and IGF II. Their relations with serum and cerebrospinal fluid IGF binding proteins.
EP0289314B1 (de) Verwendung von IGF-II zur Behandlung von Knochenkrankheiten
Mizuno et al. Cloning and sequence of cDNA encoding a peptide C-terminal α-amidating enzyme from Xenopuslaevis
Kuo et al. Amino acid sequence and characterization of a heparin-binding neurite-promoting factor (p18) from bovine brain.
Arimura et al. Isolation and identification of C-type natriuretic peptide in chicken brain
WO1986007595A1 (en) Fibroblast growth factor
CA2071538C (en) Hpth (1-37) fragment, its production, drug containing it and its use
JPH085797B2 (ja) 細胞増殖刺激剤
JP2823690B2 (ja) プロテアーゼ耐性ｐｄｇｆ及び使用法
Agerberth et al. Isolation and characterization of a 60-residue intestinal peptide structurally related to the pancreatic secretory type of trypsin inhibitor: influence on insulin secretion.
AU665034B2 (en) Production of human parathyroid hormone from microorganisms
US5744444A (en) HPTH-fragment-(1-37), the preparation thereof, medicaments containing same and the use thereof
Bajaj et al. Coypu insulin. Primary structure, conformation and biological properties of a hystricomorph rodent insulin
Matsuo et al. Molecular biology of atrial natriuretic peptides
WO1989010934A1 (en) Procalcitonin peptides
US5474982A (en) PDGF analogs and methods of use
EP0315118A2 (de) Endothelin kodierendes DNA und dessen Verwendung
EP0384731B1 (de) Osteogenische Wachstumfaktoren, die aus sich regenerierendem Knochenmark identifiziert werden
JP2002538757A (ja) 食欲制御活性を有するポリペプチド
CA1297814C (en) Process for production of insulin-like growth factor i and plasmid for production thereof

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A1

Designated state(s): AU DK FI JP KR NO

AL Designated countries for regional patents

Kind code of ref document: A1

Designated state(s): AT BE CH DE FR GB IT LU NL SE

WWE Wipo information: entry into national phase

Ref document number: 1989907003

Country of ref document: EP

WWE Wipo information: entry into national phase

Ref document number: 905453

Country of ref document: FI

WWP Wipo information: published in national office

Ref document number: 1989907003

Country of ref document: EP

WWW Wipo information: withdrawn in national office

Ref document number: 1989907003

Country of ref document: EP