WO1987000832A3 - Tetracycline antibiotics, their preparation, antibiotic compositions containing them, and microorganisms useful in their preparation - Google Patents

Tetracycline antibiotics, their preparation, antibiotic compositions containing them, and microorganisms useful in their preparation Download PDF

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Publication number
WO1987000832A3
WO1987000832A3 PCT/US1986/001587 US8601587W WO8700832A3 WO 1987000832 A3 WO1987000832 A3 WO 1987000832A3 US 8601587 W US8601587 W US 8601587W WO 8700832 A3 WO8700832 A3 WO 8700832A3
Authority
WO
WIPO (PCT)
Prior art keywords
preparation
compositions containing
tetracycline antibiotics
antibiotic compositions
microorganisms useful
Prior art date
Application number
PCT/US1986/001587
Other languages
French (fr)
Other versions
WO1987000832A2 (en
Inventor
Elizabeth Bargmann Smith
Hanan Karaman Munayyer
Michael Joseph Ryan
George Henry Miller
Mahesh Gordhandas Patel
Ann Camille Horan
Joseph Anthony Marquez
Richard Willis Vaughan
Manohar Gopal Kalyanpor
Jay Allan Waitz
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/764,275 external-priority patent/US4752605A/en
Application filed by Schering Corp filed Critical Schering Corp
Publication of WO1987000832A2 publication Critical patent/WO1987000832A2/en
Priority to DK176787A priority Critical patent/DK176787A/en
Publication of WO1987000832A3 publication Critical patent/WO1987000832A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P29/00—Preparation of compounds containing a naphthacene ring system, e.g. tetracycline
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/03—Actinomadura

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

7-Chlorotetracycline derivatives as novel antibiotics preparable by cultivation of strains of Actinomadura brunnea and Dactylosporangium vescum. They are active against gram-positive and gram-negative aerobes.
PCT/US1986/001587 1985-08-08 1986-08-06 Tetracycline antibiotics, their preparation, antibiotic compositions containing them, and microorganisms useful in their preparation WO1987000832A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
DK176787A DK176787A (en) 1985-08-08 1987-04-07 TETRACYCLINE ANTIBIOTICS, THEIR PREPARATION, ANTIBIOTIC AGENTS CONTAINING SUCH ANTIBIOTICS AND MICRO-ORGANISMS THAT MAY BE USED FOR THEIR PREPARATION

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US76374085A 1985-08-08 1985-08-08
US76374285A 1985-08-08 1985-08-08
US763,742 1985-08-08
US763,740 1985-08-08
US06/764,275 US4752605A (en) 1985-08-09 1985-08-09 7-chloro-4a-hydroxy-8-methoxytetracycline, antibiotic compositions containing them and a method of using
US764,275 1985-08-09

Publications (2)

Publication Number Publication Date
WO1987000832A2 WO1987000832A2 (en) 1987-02-12
WO1987000832A3 true WO1987000832A3 (en) 1987-06-18

Family

ID=27419573

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1986/001587 WO1987000832A2 (en) 1985-08-08 1986-08-06 Tetracycline antibiotics, their preparation, antibiotic compositions containing them, and microorganisms useful in their preparation

Country Status (3)

Country Link
EP (1) EP0232373A1 (en)
DK (1) DK176787A (en)
WO (1) WO1987000832A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5024839A (en) * 1987-12-24 1991-06-18 E. R. Squibb & Sons, Inc. Dactylocycline A and dactylocycline B

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH373375A (en) * 1957-04-05 1963-11-30 American Cyanamid Co Process for preparing tetracyclines
US3360559A (en) * 1964-11-30 1967-12-26 American Cyanamid Co Substituted 1, 3, 4, 10, 11, 12-hexahydroxynaphthacene-2-carboxamides
FR1553651A (en) * 1962-11-05 1969-01-17

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH373375A (en) * 1957-04-05 1963-11-30 American Cyanamid Co Process for preparing tetracyclines
FR1553651A (en) * 1962-11-05 1969-01-17
US3360559A (en) * 1964-11-30 1967-12-26 American Cyanamid Co Substituted 1, 3, 4, 10, 11, 12-hexahydroxynaphthacene-2-carboxamides

Also Published As

Publication number Publication date
DK176787A (en) 1987-06-09
WO1987000832A2 (en) 1987-02-12
DK176787D0 (en) 1987-04-07
EP0232373A1 (en) 1987-08-19

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