WO1983004309A1 - Procede de preparation d'une serie d'echantillons pour l'analyse de melanges et installation pour l'execution automatique du procede - Google Patents
Procede de preparation d'une serie d'echantillons pour l'analyse de melanges et installation pour l'execution automatique du procede Download PDFInfo
- Publication number
- WO1983004309A1 WO1983004309A1 PCT/CH1983/000038 CH8300038W WO8304309A1 WO 1983004309 A1 WO1983004309 A1 WO 1983004309A1 CH 8300038 W CH8300038 W CH 8300038W WO 8304309 A1 WO8304309 A1 WO 8304309A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- filter
- sample
- filter strip
- series
- strip
- Prior art date
Links
- 238000000034 method Methods 0.000 title claims abstract description 17
- 239000000203 mixture Substances 0.000 title claims abstract description 4
- 238000002360 preparation method Methods 0.000 title claims description 9
- 238000009434 installation Methods 0.000 title 1
- 239000007788 liquid Substances 0.000 claims abstract description 12
- 238000004458 analytical method Methods 0.000 claims abstract description 9
- 239000000706 filtrate Substances 0.000 claims abstract description 4
- 239000003153 chemical reaction reagent Substances 0.000 claims description 5
- 238000004519 manufacturing process Methods 0.000 claims description 3
- 238000004080 punching Methods 0.000 claims description 3
- 238000011109 contamination Methods 0.000 abstract description 5
- 238000001914 filtration Methods 0.000 abstract description 5
- 239000000376 reactant Substances 0.000 abstract 1
- 238000007792 addition Methods 0.000 description 4
- 238000004140 cleaning Methods 0.000 description 4
- 239000000463 material Substances 0.000 description 3
- 238000005070 sampling Methods 0.000 description 3
- 230000000694 effects Effects 0.000 description 2
- 238000007789 sealing Methods 0.000 description 2
- KKEBXNMGHUCPEZ-UHFFFAOYSA-N 4-phenyl-1-(2-sulfanylethyl)imidazolidin-2-one Chemical compound N1C(=O)N(CCS)CC1C1=CC=CC=C1 KKEBXNMGHUCPEZ-UHFFFAOYSA-N 0.000 description 1
- 230000005540 biological transmission Effects 0.000 description 1
- 239000007853 buffer solution Substances 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 239000007789 gas Substances 0.000 description 1
- 239000011521 glass Substances 0.000 description 1
- 239000003365 glass fiber Substances 0.000 description 1
- 230000001900 immune effect Effects 0.000 description 1
- 230000002572 peristaltic effect Effects 0.000 description 1
- 238000003825 pressing Methods 0.000 description 1
- 230000001681 protective effect Effects 0.000 description 1
- 238000005096 rolling process Methods 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 238000013022 venting Methods 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/40—Concentrating samples
- G01N1/4077—Concentrating samples by other techniques involving separation of suspended solids
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/40—Concentrating samples
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/286—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q involving mechanical work, e.g. chopping, disintegrating, compacting, homogenising
- G01N2001/2873—Cutting or cleaving
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/286—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q involving mechanical work, e.g. chopping, disintegrating, compacting, homogenising
- G01N2001/2873—Cutting or cleaving
- G01N2001/288—Filter punches
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/11—Automated chemical analysis
- Y10T436/110833—Utilizing a moving indicator strip or tape
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
- Y10T436/25375—Liberation or purification of sample or separation of material from a sample [e.g., filtering, centrifuging, etc.]
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
- Y10T436/2575—Volumetric liquid transfer
Definitions
- the invention relates to a method for producing a series of samples for the analysis of batches, in which the batch in question is removed from a vessel with a liquid sample batch and placed in places on a step-by-step filter strip, and the filtrate that is no longer required is suctioned off from the rear of the filter strip and the filter residue is prepared for the analysis.
- Such methods are e.g. used for the preparation of samples for immunological analyzes or for the analysis of suspended substances in liquids or gases.
- a filter strip is used to produce the samples, which is attached to a carrier tape made of stable material and provided with windows in places.
- the samples can be protected against contamination by covering on both sides and stored by rolling up the carrier tape.
- Such a filter strip with carrier tape is suitable, but is only suitable for dry samples and, moreover, is very complex in terms of material and manufacture.
- the batch is pipetted onto the filter strip for filtering. Without the use of special protective measures, there is a certain risk of contamination.
- an additional feed pump is required to supply the batch to the pipette.
- the feed path is lengthened and, as a result, and because of the use of slow-working peristaltic pumps, the duration of the batch transport is increased, which in certain cases can lead to incorrect changes in the sample batch.
- a longer feed path also requires an increased effort
- the object of the invention is to provide a method of the type mentioned at the outset, which makes it possible to produce samples for batch analyzes while avoiding the disadvantages mentioned and with simpler and less complex means and thereby achieve shorter throughput times and a reduction in the risk of contamination .
- the feed pump is dispensed with in the feed path. This can be kept shorter, which enables a faster throughput and facilitates cleaning.
- the complete sealing at the filter site offers protection against any material exchange with the environment. Parts of the filter containing
- Filter strips are punched out each time the batch is deposited and transferred to sample vessels.
- the strength of the filter strip is therefore less stringent than when the entire filter strip is stored with the associated mechanical stresses, which is why a carrier tape can be dispensed with.
- a method which works with unreinforced filter strips, but the filter strips provided with coated filter points are cut by hand into parts with one filter point each and introduced into the sample vessels. Contamination and errors can hardly be avoided with this method, and handling is cumbersome and time-consuming.
- the invention also relates to a device for the automatic implementation of the method, which is characterized by the features specified in claim 2.
- An exemplary embodiment of the device according to the invention is shown schematically in the drawing. It can be a separately constructed filter station that can be used in an automatic analysis system for series analysis.
- the prepared and optionally pretreated sample batches are located in open or closed vessels, which e.g. progressively moved in a chain and successively fed to the filter station shown. According to the drawing, such a sample preparation vessel 1 is located at the point intended for sampling.
- a sampling device with a raised and lowered cannula 2 is used, which is connected to a lifting motor 3.
- a pipette 4 is mechanically verbun ⁇ to, via which any additions and the "Rein Trentsflüs ⁇ supplied fluid.
- the filter strip 5 for example made of glass fiber paper, is removed from a roller 6 and moved along a guide track 9 step by step by means of feed rollers 7, 8.
- the filtering device 10 consists of a suction head 12 arranged below the guideway and a vertically movable bell 13 arranged above the guideway opposite the suction head.
- the suction head 12 is at the level of the Guide track 9 is closed by a filter carrier 14, for example in the form of a sintered glass plate, and connected to a vacuum pump (not shown) via a controlled valve 15.
- the bell 13 is connected to a lifting motor 16, which can press the bell against the suction head 12 on the filter strip lying in between, so that the filter point is sealed on both sides.
- a sealing ring 17 can be provided at the lower edge of the bell.
- a line 18 with a preferably height-adjustable mouth is inserted into the bell 13 and is directly connected to the cannula 2 of the removal device via a hose 19.
- the punching device 11 has a punch 20 and a lifting motor 21 for its actuation. In this way, a disk of the filter strip is punched out at the punched opening 22 in the guideway 9.
- a darning needle 23 is guided longitudinally in the punch 20 and connected to a lifting motor 24.
- the stuffing needle 23 conveys the punched-out disk into a sample receptacle 25 underneath, which e.g. again in a chain of receptacles.
- the reagent liquid is fed to the stuffing needle 23 via a hose 26.
- the filtering station works in time with the feed devices (not shown) for the transport of the preparation vessels 1 and the receiving vessels 25.
- a program control device can be provided which controls the activity of the lifting motors 3, 16, 21, 24, of the The drive of the feed rollers 7, 8 and the valve 15 controls and, for example, starts or stops the vessel of a chain of sample preparation vessels from the first and last to the removal device. This gives e.g. the following working method of the filter station:
- the cannula 2 is lowered into the preparation vessel 1 and the bell 13 onto the stationary filter strip 5. Then the necessary addition is made, e.g. in the form of a buffer solution, via the pipette 4. Before the end of this addition, the valve 15 is opened, whereby the suction power of the vacuum pump comes into effect and the sample batch from the batch vessel 1 via the cannula 2 and the hose 19 to the filter point within the bell 13 transported. As a result of the pumpless connection between cannula 2 and bell 13, this transmission takes place within a few seconds, so that the duration of the influence of any addition on the sample can be kept within desired limits.
- the vessel chains and the filter strip 5 are advanced by one step, so that the next batch vessel 1 comes into the removal position, the first sample collection vessel 25 into the acquisition position and the filter point covered with the filter residue comes under the punch 20 .
- the reagent liquid for example a scintillation liquid in the case of radioimmunological samples, is fed through the hose 26 through the latter.
- the end of the stuffing needle 23 is preferably expanded in a trumpet shape so that the filter disc is grasped as close as possible to the edge and cannot come into contact with the outside of the stuffing needle when it is inserted into the receptacle 25.
- Reagent liquid also serves to clean the darning needle.
- the supply of the various liquids via the pipette 4 and the hose 26 is preferably carried out by selectively connectable dispensers.
- the lifting motors 3 and 16 can be replaced by a single lifting motor with a suitable arrangement of the removal device and the bell 13.
- An overpressure spring is preferably provided for pressing the bell 13 onto the filter strip 5.
- a filter disc can be punched out and the next sample can be filtered at the same time.
Landscapes
- Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Sampling And Sample Adjustment (AREA)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE8383900896T DE3371119D1 (en) | 1982-06-05 | 1983-03-24 | Device for the automatic preparation of a series of samples to analyze mixtures |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CH348582A CH655392B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1982-06-05 | 1982-06-05 | |
CH3485/82-7 | 1982-06-05 |
Publications (1)
Publication Number | Publication Date |
---|---|
WO1983004309A1 true WO1983004309A1 (fr) | 1983-12-08 |
Family
ID=4257002
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/CH1983/000038 WO1983004309A1 (fr) | 1982-06-05 | 1983-03-24 | Procede de preparation d'une serie d'echantillons pour l'analyse de melanges et installation pour l'execution automatique du procede |
Country Status (5)
Cited By (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0148290A1 (en) * | 1983-12-14 | 1985-07-17 | Försvarets Forskningsanstalt | Method and device at the analysis of liquid samples |
EP0152185A1 (en) * | 1984-01-17 | 1985-08-21 | Ecc International Limited | Measurement of physical properties of the solid component of a slurry |
DE4041433A1 (de) * | 1990-12-21 | 1992-06-25 | Siemens Ag | Einrichtung zur aufbereitung von mehrphasengemischen fuer die analyse |
EP0583078A3 (en) * | 1992-07-14 | 1994-11-17 | Wallac Oy | Sample handling apparatus and method and sample collection system. |
WO1995027195A1 (en) * | 1994-03-31 | 1995-10-12 | Millipore Corporation | Membrane cutter and retriever |
EP1393079A4 (en) * | 2001-05-25 | 2007-03-14 | Proteome Systems Intellectual | LIQUID HANDLING AGENT FOR AN EXCISIONING DEVICE |
WO2011067309A1 (en) * | 2009-12-04 | 2011-06-09 | Whatman International Ltd | Methods and systems to prevent punch loss during automated sample processing |
CN110005959A (zh) * | 2019-04-22 | 2019-07-12 | 中国石油天然气集团有限公司 | 一种输气管道气质分析一体化整合检测装置 |
US10376692B2 (en) | 2002-07-04 | 2019-08-13 | Inovio As | Electroporation device and injection apparatus |
Families Citing this family (29)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4849077A (en) * | 1984-08-06 | 1989-07-18 | Akademie Der Wissenschaften Der Ddr | Process for solid phase-sequencing of nucleic acid fragments |
US4954319A (en) * | 1987-12-16 | 1990-09-04 | Fuji Photo Film Co., Ltd. | Mechanism for supplying analytical tape for biochemical analysis by predetermined length |
DE4209871C2 (de) * | 1991-05-28 | 1997-04-30 | Dade Int Inc | Einrichtung zur automatischen Untersuchung von Blutproben |
US5210927A (en) * | 1991-06-17 | 1993-05-18 | Ways & Means, Inc. | Pipette tip filter inserter and method therefore |
US5508200A (en) * | 1992-10-19 | 1996-04-16 | Tiffany; Thomas | Method and apparatus for conducting multiple chemical assays |
US5425263A (en) * | 1993-06-01 | 1995-06-20 | Barringer Research Limited | Method for inspecting an article for concealed substances |
TW384398B (en) * | 1995-12-19 | 2000-03-11 | Toa Medical Electronics | Sample agitating and sucking apparatus |
ES2350702T3 (es) * | 1998-01-12 | 2011-01-26 | Massachusetts Institute Of Technology | Sistema para analizar una pluralidad de muestras. |
US6200816B1 (en) * | 1998-10-21 | 2001-03-13 | The United States Of America As Represented By The Department Of Energy | Method for measuring particulate and gaseous metals in a fluid stream, device for measuring particulate and gaseous metals in a fluid stream |
US6465749B1 (en) | 2000-07-07 | 2002-10-15 | Los Robles Advertising, Inc. | Magnetostrictive mass sensing apparatus and method |
AU2001284555A1 (en) * | 2000-07-31 | 2002-02-13 | Strategic Technology Limited | Sample preparation system |
US6958234B2 (en) * | 2003-04-03 | 2005-10-25 | Hospira, Inc. | Automatic microbial air sampling system and method |
US20050218067A1 (en) * | 2003-04-10 | 2005-10-06 | Cuno Incorporated | Ablated predetermined surface geometric shaped boundary formed on porous material mounted on a substrate and methods of making same |
US20070056898A1 (en) * | 2004-05-13 | 2007-03-15 | Keith Wesner | Ablated predetermined surface geometric shaped boundary formed on porous material mounted on a substrate and methods of making same |
GB0421352D0 (en) * | 2004-09-24 | 2004-10-27 | City Tech | Sampling and analysis system and method |
US9485917B2 (en) | 2006-12-15 | 2016-11-08 | Ecovative Design, LLC | Method for producing grown materials and products made thereby |
US20110108495A1 (en) * | 2009-11-06 | 2011-05-12 | Matthew Neil Mynott Taylor | Specimen Analysis and Extraction System |
CN102890015B (zh) * | 2012-05-24 | 2015-05-27 | 深圳国技仪器有限公司 | 防尘防倒吸装置 |
US20140056653A1 (en) * | 2012-08-22 | 2014-02-27 | Christopher Scully | Method and Machine for Filling 3D Cavities with Bulk Material |
US11277979B2 (en) | 2013-07-31 | 2022-03-22 | Ecovative Design Llc | Mycological biopolymers grown in void space tooling |
US20150101509A1 (en) | 2013-10-14 | 2015-04-16 | Gavin R. McIntyre | Method of Manufacturing a Stiff Engineered Composite |
US10537070B2 (en) | 2015-04-15 | 2020-01-21 | Ecovative Design Llc | Process for the production of mycelial composite surfaces in a roll-to-roll format |
CN109153964B (zh) | 2016-03-01 | 2023-06-13 | 芬德集团公司 | 丝状真菌生物垫、及其生产方法和使用方法 |
CA3058212A1 (en) | 2017-03-31 | 2018-10-04 | Jessie Hannah Kaplan-Bei | Solution based post-processing methods for mycological biopolymer material and mycological product made thereby |
US11266085B2 (en) | 2017-11-14 | 2022-03-08 | Ecovative Design Llc | Increased homogeneity of mycological biopolymer grown into void space |
US11920126B2 (en) | 2018-03-28 | 2024-03-05 | Ecovative Design Llc | Bio-manufacturing process |
US11293005B2 (en) | 2018-05-07 | 2022-04-05 | Ecovative Design Llc | Process for making mineralized mycelium scaffolding and product made thereby |
WO2019226823A1 (en) | 2018-05-24 | 2019-11-28 | Ecovative Design Llc | Process and apparatus for producing mycelium biomaterial |
EP3860370A4 (en) | 2018-10-02 | 2022-10-12 | Ecovative Design LLC | A bioreactor paradigm for the production of secondary extra-particle hyphal matrices |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3244287A (en) * | 1962-12-21 | 1966-04-05 | Coleman Instr Corp | Continuous filtration |
DE2241646A1 (de) * | 1972-08-24 | 1974-03-28 | Friedrich Dr Rer Nat D Erhardt | Streifen mit einer reihe radioimmunologischer proben sowie verfahren und vorrichtung zur herstellung eines solchen streifens |
US3923463A (en) * | 1972-10-09 | 1975-12-02 | Kenneth Dawson Bagshawe | Apparatus for performing chemical and biological analysis |
US4167875A (en) * | 1976-08-05 | 1979-09-18 | Meakin John C | Filtration method and apparatus |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3554700A (en) * | 1968-05-06 | 1971-01-12 | Scientific Industries | Method for obtaining a known volume of liquid and absorption apparatus therefor |
US3940250A (en) * | 1972-01-31 | 1976-02-24 | Vitatect Corporation | Testing using luminescent reaction |
DE2324056A1 (de) * | 1973-05-12 | 1974-11-21 | Faudi Feinbau | Schlammtrockenanlage |
US4341735A (en) * | 1980-03-28 | 1982-07-27 | American Cyanamid Company | Sample carrier material handling apparatus |
US4395493A (en) * | 1981-05-14 | 1983-07-26 | Coulter Electronics, Inc. | Monolayer device using filter techniques |
-
1982
- 1982-06-05 CH CH348582A patent/CH655392B/de unknown
-
1983
- 1983-03-24 EP EP83900896A patent/EP0110890B1/de not_active Expired
- 1983-03-24 DE DE8383900896T patent/DE3371119D1/de not_active Expired
- 1983-03-24 WO PCT/CH1983/000038 patent/WO1983004309A1/de active IP Right Grant
- 1983-03-24 US US06/577,626 patent/US4568520A/en not_active Expired - Fee Related
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3244287A (en) * | 1962-12-21 | 1966-04-05 | Coleman Instr Corp | Continuous filtration |
DE2241646A1 (de) * | 1972-08-24 | 1974-03-28 | Friedrich Dr Rer Nat D Erhardt | Streifen mit einer reihe radioimmunologischer proben sowie verfahren und vorrichtung zur herstellung eines solchen streifens |
US3923463A (en) * | 1972-10-09 | 1975-12-02 | Kenneth Dawson Bagshawe | Apparatus for performing chemical and biological analysis |
US4167875A (en) * | 1976-08-05 | 1979-09-18 | Meakin John C | Filtration method and apparatus |
Cited By (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0148290A1 (en) * | 1983-12-14 | 1985-07-17 | Försvarets Forskningsanstalt | Method and device at the analysis of liquid samples |
EP0152185A1 (en) * | 1984-01-17 | 1985-08-21 | Ecc International Limited | Measurement of physical properties of the solid component of a slurry |
US4704899A (en) * | 1984-01-17 | 1987-11-10 | English Clays Lovering Pochin & Company, Limited | Measurement of physical properties of the solid component of a slurry |
DE4041433A1 (de) * | 1990-12-21 | 1992-06-25 | Siemens Ag | Einrichtung zur aufbereitung von mehrphasengemischen fuer die analyse |
EP0583078A3 (en) * | 1992-07-14 | 1994-11-17 | Wallac Oy | Sample handling apparatus and method and sample collection system. |
WO1995027195A1 (en) * | 1994-03-31 | 1995-10-12 | Millipore Corporation | Membrane cutter and retriever |
EP1393079A4 (en) * | 2001-05-25 | 2007-03-14 | Proteome Systems Intellectual | LIQUID HANDLING AGENT FOR AN EXCISIONING DEVICE |
US10376692B2 (en) | 2002-07-04 | 2019-08-13 | Inovio As | Electroporation device and injection apparatus |
US11471675B2 (en) | 2002-07-04 | 2022-10-18 | Inovio Pharmaceuticals, Inc. | Electroporation device and injection apparatus |
WO2011067309A1 (en) * | 2009-12-04 | 2011-06-09 | Whatman International Ltd | Methods and systems to prevent punch loss during automated sample processing |
CN110005959A (zh) * | 2019-04-22 | 2019-07-12 | 中国石油天然气集团有限公司 | 一种输气管道气质分析一体化整合检测装置 |
Also Published As
Publication number | Publication date |
---|---|
EP0110890B1 (de) | 1987-04-22 |
DE3371119D1 (en) | 1987-05-27 |
CH655392B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1986-04-15 |
EP0110890A1 (de) | 1984-06-20 |
US4568520A (en) | 1986-02-04 |
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