Classifications

• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
  • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
  • A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
  • A61M1/32—Oxygenators without membranes
• • B—PERFORMING OPERATIONS; TRANSPORTING
  • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
  • B01D—SEPARATION
  • B01D39/00—Filtering material for liquid or gaseous fluids
  • B01D39/14—Other self-supporting filtering material ; Other filtering material
  • B01D39/16—Other self-supporting filtering material ; Other filtering material of organic material, e.g. synthetic fibres
  • B01D39/1669—Cellular material
  • B01D39/1676—Cellular material of synthetic origin
• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
  • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
  • A61M1/34—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration
• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
  • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
  • A61M1/34—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration
  • A61M1/3403—Regulation parameters
• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
  • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
  • A61M1/34—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration
  • A61M1/3403—Regulation parameters
  • A61M1/3406—Physical characteristics of the filtrate, e.g. urea

Definitions

• Taishiki is related to the filtration of stored blood for transfusion (or thick red blood cells for transfusion), and has a small clogging and microscopic blood coagulation (microa ggggre gat). O blood filters that can effectively remove o
• the size of aggregates to be removed from the blood is considered as follows: ⁇ Among the formed components in the blood, erythrocytes have a maximum diameter of about 8 ⁇ , and the sizes of leukocytes and platelets are 6 ⁇ 20 each
• the life span of red blood cells is about 120 days, while that of white blood cells and platelets is 1 to 7 days and 7 to 14 days, respectively.
• the target ⁇ storing date to the ring blood ⁇ is around 10 days ago, the majority of leukocytes and platelets can be considered to be dead components that have already lost their function. According to 1 0 ⁇ ]]? Large 3 ⁇ 4 particles are not useful 3 ⁇ 4 but are not S, j ?, and should be removed o
• O Screen filters are used to remove micro-aggregates from the lattice-like weave of monofilament yarns of thin synthetic fibers by simple sieving.
• the size of the clean pores determines the size of the particles to be filtered. 0 Due to such an effect, the ellipticity (removal rate of the particles) of the filtration is very high.
• Ruta is made of fibrous packing, non-woven fabric, soft sponge, etc.), and has a very large blood contact area.
• the large processing capacity which is the advantage of a deb-filter, and the high accuracy of the screen filter are combined, and the coarse filter is used as a deb-filter, and the final filter is used as a filter. 0 those of the multilayer was a clean filter has been increasing
• the present inventors have conducted intensive studies on such a material for a blood filter, and as a result, have found that a porcelain ⁇ mec '' porous body made of a relatively hard plastic and having a specific mesh-like continuous structure having a high U-voiding rate is used. I filter Ichie Leme emissions reaching fact that excellent heading invention as bets 0
• the filter made of the plastic porous body of the invention has a large blood-passing capacity, which is a characteristic of a deb-strainer, and is filtered by deformation or the like, which is a drawback of a debs filter such as a conventional soft sponge. It is a solution to the problem of low accuracy.
• Sintered bodies such as resin particles can be considered as a porous material with sufficient self-supporting properties, but the sintered body has a limitation on body to porosity. Oh, even if the same amount of material is used, the filtering surface ridge is substantially smaller.] Also, the pore channels are uniform and it is difficult to make the inner surface smooth.
• a filter material comprising one or a plurality of filter elements
• at least one of the filter elements has a pore diameter of 200 having a continuous eyelet.
• a blood filter characterized by comprising a porous body is provided.
• the blood filter of the present invention does not require a multi-stage element as in the case of a conventional filter, such as a general commercially available filter. It is useful from the standpoint of size and weight reduction, as it is possible to obtain filament o
• a plastic resin obtained by a dissolution method using a thermoplastic resin as a material is suitable.
• the dissolution method is a treatment of a plastic sheet containing a solvent-soluble powdered powder with a solvent; (4) The powder is eluted to obtain a continuously open porous body.
• the volume porosity of the porous body can be determined by the size and addition amount of the fine powder particles. Use of powder with a uniform particle size results in a uniform pore size and relatively uniform pore channels.
• a thermoplastic resin a porous material with a high porosity is constructed. Any material that exhibits sufficient compressive strength when used can be used.o
• a relatively hard, mature plastic resin having such properties includes Bolibul formal o.
• the polybulformal sponge prepared by the dissolution method is reticulated (branched). It has a structure, and has a structure that is mechanically stable in spite of its high porosity, and can be suitably used in the present invention.
• This plastic porous body is different from a conventional Debs filter / Screen filter. They may be used in combination. It is better to combine them in terms of removal rate o
• the blood just before the expiration date (U 21 days after blood collection) expires in a single ring blood is usually 1000 or more. It is practically preferable to be able to perform filtration without any problems. O In this case, it is sufficient that the filtration speed is (25 min). In actual blood blood, filtration is performed at a reduced speed. lever use in any Bayoi 0 filter Ereme down bets even state that is achieved can the speed has opened the D grain having a small pore diameter, the removal rate is naturally improved, deformability such as blood In systems with a large number of particles, the ease with which pores are clogged U increases sharply as the pore size of the filter element decreases.o
• the thickness of the porous porosity of the Proterozoic plastic with a continuous open pore with a pore diameter of 50 to -150 on the controlled side of the porosity and a more reticulated 3 ⁇ 4 gun tissue 0. ⁇ ⁇ 5.0 « ⁇ blast
• ⁇ ⁇ Blood filter consisting of a filter element combined with a porous porous material, and a reticulated continuous gun tissue with a continuous open pore with a pore diameter of 100 to 200 ⁇ 0.5 to 5. 0 It turned out that a blood filter in which a plastic porous body was interposed was preferred.
• Bolibullformal porous sheet as a plastic porous body having continuous pores having a pore diameter of 50 to 150 Z ⁇ m or 100 to 200 or 0 or 2 kinds.
• High filter accuracy and large size ⁇ Blood filtration capacity can be obtained by using a filter composed of 8 types of porous materials o
• the pore diameter of the invention is the apparent diameter when observing with a microscope the size of the open pore size on the surface or cut surface of the porous body. Even if a filter element (pore diameter: 200-500 / im or 50-: 150i) is used, particles that are much smaller than the pore diameter (micro-aggregates, etc.) will be entrapped and reach the purpose of filtration. O This is because the porous porcelain of the present invention has a uniform, continuous, open eye-like (dendritic) structure from continuous open pores, and is liable to deform, such as microaggregates.
• the vertical surface between the liquid level of the blood tank and the bottom of the filter unit is 50 to 60 «B. o
• the filter element used for filtration. the elution method 0 both made of Helsingborg Byuruhoru Mar shown in table 1
• Subonjishi bets (Bae Louis one coater, Kanebo synthetic chemical Co., Ltd.) Aru o
• FIG. 1 is a schematic diagram showing a partial cross section of a test device using blood 7-liters of the present invention.

Landscapes

• Health & Medical Sciences (AREA)
• Heart & Thoracic Surgery (AREA)
• Hematology (AREA)
• General Health & Medical Sciences (AREA)
• Vascular Medicine (AREA)
• Engineering & Computer Science (AREA)
• Anesthesiology (AREA)
• Biomedical Technology (AREA)
• Veterinary Medicine (AREA)
• Life Sciences & Earth Sciences (AREA)
• Animal Behavior & Ethology (AREA)
• Public Health (AREA)
• Emergency Medicine (AREA)
• Chemical Kinetics & Catalysis (AREA)
• Chemical & Material Sciences (AREA)
• Urology & Nephrology (AREA)
• External Artificial Organs (AREA)
• Filtering Materials (AREA)
• Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Priority Applications (1)

Applications Claiming Priority (2)

Publications (1)

Family

ID=13252318

Family Applications (1)

Country Status (4)

Cited By (1)

Families Citing this family (3)

Citations (1)

• 1982
  • 1982-04-16 JP JP57064237A patent/JPS58180425A/ja active Pending
• 1983
  • 1983-04-15 WO PCT/JP1983/000124 patent/WO1983003550A1/ja active Application Filing
  • 1983-04-15 DE DE19833340221 patent/DE3340221T1/de not_active Withdrawn
  • 1983-12-16 SE SE8306986A patent/SE441894B/sv not_active IP Right Cessation

Patent Citations (1)

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