WO1979000922A1 - Uracil derivatives,process for preparing the same,and oncotic preparation thereof - Google Patents
Uracil derivatives,process for preparing the same,and oncotic preparation thereof Download PDFInfo
- Publication number
- WO1979000922A1 WO1979000922A1 PCT/JP1979/000089 JP7900089W WO7900922A1 WO 1979000922 A1 WO1979000922 A1 WO 1979000922A1 JP 7900089 W JP7900089 W JP 7900089W WO 7900922 A1 WO7900922 A1 WO 7900922A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- oncotic
- preparation
- preparing
- same
- uracil derivatives
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- ISAKRJDGNUQOIC-UHFFFAOYSA-N Uracil Chemical class O=C1C=CNC(=O)N1 ISAKRJDGNUQOIC-UHFFFAOYSA-N 0.000 title 1
- WFDIJRYMOXRFFG-UHFFFAOYSA-N Acetic anhydride Chemical compound CC(=O)OC(C)=O WFDIJRYMOXRFFG-UHFFFAOYSA-N 0.000 abstract 3
- YZONFYDGFVRFEN-UHFFFAOYSA-N 1-acetyl-5-fluoro-3-(2-methylphenyl)pyrimidine-2,4-dione Chemical compound O=C1N(C(=O)C)C=C(F)C(=O)N1C1=CC=CC=C1C YZONFYDGFVRFEN-UHFFFAOYSA-N 0.000 abstract 1
- OVGDAVVFKDPXIC-UHFFFAOYSA-N 1-acetyl-5-fluoropyrimidine-2,4-dione Chemical compound CC(=O)N1C=C(F)C(=O)NC1=O OVGDAVVFKDPXIC-UHFFFAOYSA-N 0.000 abstract 1
- IIZPXYDJLKNOIY-JXPKJXOSSA-N 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine Chemical compound CCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCC\C=C/C\C=C/C\C=C/C\C=C/CCCCC IIZPXYDJLKNOIY-JXPKJXOSSA-N 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000005456 glyceride group Chemical group 0.000 abstract 1
- 229940067606 lecithin Drugs 0.000 abstract 1
- 235000010445 lecithin Nutrition 0.000 abstract 1
- 239000000787 lecithin Substances 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- -1 o-toluyl halide Chemical class 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
- 229940035893 uracil Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/52—Two oxygen atoms
- C07D239/54—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals
- C07D239/545—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals with other hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/553—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals with other hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms with halogen atoms or nitro radicals directly attached to ring carbon atoms, e.g. fluorouracil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP78/43496 | 1978-04-12 | ||
| JP4349678A JPS54135782A (en) | 1978-04-12 | 1978-04-12 | 11acetyll*33ootoluyl**55fluorouracil and its manufacture andantitumor |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| WO1979000922A1 true WO1979000922A1 (en) | 1979-11-15 |
Family
ID=12665314
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PCT/JP1979/000089 WO1979000922A1 (en) | 1978-04-12 | 1979-04-05 | Uracil derivatives,process for preparing the same,and oncotic preparation thereof |
Country Status (2)
| Country | Link |
|---|---|
| JP (1) | JPS54135782A (enrdf_load_stackoverflow) |
| WO (1) | WO1979000922A1 (enrdf_load_stackoverflow) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6036411A (ja) * | 1983-08-09 | 1985-02-25 | Okada Raifu Corp:Kk | 抗腫瘍剤及びその製造法 |
| JPS6296078U (enrdf_load_stackoverflow) * | 1985-12-02 | 1987-06-19 |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5186480A (en) * | 1975-01-22 | 1976-07-29 | Asahi Chemical Ind | 55 furuororashirujudotainoseiho |
-
1978
- 1978-04-12 JP JP4349678A patent/JPS54135782A/ja active Granted
-
1979
- 1979-04-05 WO PCT/JP1979/000089 patent/WO1979000922A1/ja unknown
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5186480A (en) * | 1975-01-22 | 1976-07-29 | Asahi Chemical Ind | 55 furuororashirujudotainoseiho |
Also Published As
| Publication number | Publication date |
|---|---|
| JPS54135782A (en) | 1979-10-22 |
| JPS5550023B2 (enrdf_load_stackoverflow) | 1980-12-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| AK | Designated states |
Designated state(s): BR DK SU US |
|
| AL | Designated countries for regional patents |
Designated state(s): CH DE FR GB SE |