UY39705A - Novedosos compuestos útiles como agonistas de sting y sus usos - Google Patents
Novedosos compuestos útiles como agonistas de sting y sus usosInfo
- Publication number
- UY39705A UY39705A UY0001039705A UY39705A UY39705A UY 39705 A UY39705 A UY 39705A UY 0001039705 A UY0001039705 A UY 0001039705A UY 39705 A UY39705 A UY 39705A UY 39705 A UY39705 A UY 39705A
- Authority
- UY
- Uruguay
- Prior art keywords
- novel compounds
- compounds useful
- sting agonists
- compounds
- sting
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 3
- 229940044665 STING agonist Drugs 0.000 title 1
- 239000013543 active substance Substances 0.000 abstract 1
- 239000000411 inducer Substances 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 238000003786 synthesis reaction Methods 0.000 abstract 1
- 230000014567 type I interferon production Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
- C07D495/14—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (8)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2021083783 | 2021-03-30 | ||
| CN2021090945 | 2021-04-29 | ||
| CN2021111479 | 2021-08-09 | ||
| CN2021128942 | 2021-11-05 | ||
| CN2021130097 | 2021-11-11 | ||
| CN2021138806 | 2021-12-16 | ||
| CN2021143043 | 2021-12-30 | ||
| CN2022071548 | 2022-01-12 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| UY39705A true UY39705A (es) | 2022-10-31 |
Family
ID=83457956
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| UY0001039705A UY39705A (es) | 2021-03-30 | 2022-03-29 | Novedosos compuestos útiles como agonistas de sting y sus usos |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20240116909A1 (https=) |
| EP (1) | EP4313962A4 (https=) |
| JP (1) | JP2024511832A (https=) |
| CN (1) | CN117203194A (https=) |
| AR (1) | AR125608A1 (https=) |
| TW (1) | TW202302579A (https=) |
| UY (1) | UY39705A (https=) |
| WO (1) | WO2022206725A1 (https=) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN118524854A (zh) * | 2021-12-17 | 2024-08-20 | 北京加科思新药研发有限公司 | 包含可用作sting激动剂的新型化合物的化合物-连接基构建体及其用途 |
| WO2024032782A1 (en) * | 2022-08-12 | 2024-02-15 | Jacobio Pharmaceuticals Co.Ltd. | Vaccine adjuvants and uses thereof |
| WO2026001915A1 (en) * | 2024-06-24 | 2026-01-02 | Jacobio Pharmaceuticals Co., Ltd. | Drug linker, conjugate thereof, and uses thereof |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3774765A4 (en) * | 2018-04-03 | 2021-12-29 | Merck Sharp & Dohme Corp. | Aza-benzothiophene compounds as sting agonists |
| JP7326319B2 (ja) * | 2018-04-03 | 2023-08-15 | メルク・シャープ・アンド・ドーム・エルエルシー | Ｓｔｉｎｇアゴニストとしてのベンゾチオフェン類及び関連する化合物 |
| CR20220029A (es) * | 2019-07-22 | 2022-03-14 | Lupin Ltd | Compuestos macrocíclicos como agonistas de sting y métodos y usos de los mismos |
-
2022
- 2022-03-29 WO PCT/CN2022/083557 patent/WO2022206725A1/en not_active Ceased
- 2022-03-29 AR ARP220100748A patent/AR125608A1/es not_active Application Discontinuation
- 2022-03-29 EP EP22778907.0A patent/EP4313962A4/en active Pending
- 2022-03-29 JP JP2023560282A patent/JP2024511832A/ja active Pending
- 2022-03-29 CN CN202280023908.7A patent/CN117203194A/zh active Pending
- 2022-03-29 TW TW111112050A patent/TW202302579A/zh unknown
- 2022-03-29 US US18/284,897 patent/US20240116909A1/en active Pending
- 2022-03-29 UY UY0001039705A patent/UY39705A/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CN117203194A (zh) | 2023-12-08 |
| JP2024511832A (ja) | 2024-03-15 |
| AR125608A1 (es) | 2023-08-02 |
| TW202302579A (zh) | 2023-01-16 |
| WO2022206725A1 (en) | 2022-10-06 |
| EP4313962A1 (en) | 2024-02-07 |
| US20240116909A1 (en) | 2024-04-11 |
| EP4313962A4 (en) | 2025-02-26 |
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