UY39029A - Uso de compuestos de aminopropionato sustituido en el tratamiento de la infección por sars-cov-2 - Google Patents
Uso de compuestos de aminopropionato sustituido en el tratamiento de la infección por sars-cov-2Info
- Publication number
- UY39029A UY39029A UY0001039029A UY39029A UY39029A UY 39029 A UY39029 A UY 39029A UY 0001039029 A UY0001039029 A UY 0001039029A UY 39029 A UY39029 A UY 39029A UY 39029 A UY39029 A UY 39029A
- Authority
- UY
- Uruguay
- Prior art keywords
- cov
- sars
- treatment
- aminopropionate
- infection
- Prior art date
Links
- QNAYBMKLOCPYGJ-UHFFFAOYSA-N Alanine Chemical class CC([NH3+])C([O-])=O QNAYBMKLOCPYGJ-UHFFFAOYSA-N 0.000 title 1
- 208000025721 COVID-19 Diseases 0.000 title 1
- 208000037847 SARS-CoV-2-infection Diseases 0.000 title 1
- 241001678559 COVID-19 virus Species 0.000 abstract 1
- -1 aminopropionate compound Chemical class 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 208000015181 infectious disease Diseases 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000012453 solvate Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/683—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
- A61K31/685—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols one of the hydroxy compounds having nitrogen atoms, e.g. phosphatidylserine, lecithin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Virology (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Molecular Biology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Epidemiology (AREA)
- Pulmonology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicinal Preparation (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Peptides Or Proteins (AREA)
Abstract
La presente solicitud se refiere al uso de un compuesto de aminopropionato sustituido representado por la Fórmula I, un isómero geométrico, una sal apta para uso farmacéutico, un solvato y/o un hidrato del mismo, y una composición farmacéutica que comprende el compuesto[,] para el tratamiento de una enfermedad o una infección causada por un SARS-CoV-2,
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202010071087.7A CN111265532A (zh) | 2020-01-21 | 2020-01-21 | 取代氨基丙酸酯类化合物在治疗2019-nCoV感染中的应用 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| UY39029A true UY39029A (es) | 2021-03-26 |
Family
ID=70992321
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| UY0001039029A UY39029A (es) | 2020-01-21 | 2021-01-21 | Uso de compuestos de aminopropionato sustituido en el tratamiento de la infección por sars-cov-2 |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US20210220377A1 (es) |
| EP (1) | EP3854403A1 (es) |
| JP (2) | JP2021116295A (es) |
| CN (2) | CN111265532A (es) |
| EA (1) | EA202092169A1 (es) |
| TW (1) | TWI805952B (es) |
| UY (1) | UY39029A (es) |
| WO (1) | WO2021147236A1 (es) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SG186830A1 (en) | 2010-07-22 | 2013-02-28 | Gilead Sciences Inc | Methods and compounds for treating paramyxoviridae virus infections |
| TWI698444B (zh) | 2014-10-29 | 2020-07-11 | 美商基利科學股份有限公司 | 製備核糖苷的方法 |
| BR112018005048B8 (pt) | 2015-09-16 | 2021-03-23 | Gilead Sciences Inc | uso de um composto antiviral ou sal do mesmo para o tratamento de uma infecção por coronaviridae |
| AU2018235754B2 (en) | 2017-03-14 | 2021-04-08 | Gilead Sciences, Inc. | Methods of treating feline coronavirus infections |
| ES2938859T3 (es) | 2017-05-01 | 2023-04-17 | Gilead Sciences Inc | Una forma cristalina de (S)-2-etilbutilo 2-(((S)-(((2R,3S,4R,5R)-5-(4-aminopirrolo[2,1-f][1,2,4]triazin-7-il)-5-ciano-3,4-dihidroxitetrahidrofuran-2-il)metoxi)(fenoxi)fosforil)amino)propanoato |
| CN111093627B (zh) | 2017-07-11 | 2024-03-08 | 吉利德科学公司 | 用于治疗病毒感染的包含rna聚合酶抑制剂和环糊精的组合物 |
| CN111265528A (zh) | 2020-01-21 | 2020-06-12 | 中国人民解放军军事科学院军事医学研究院 | 法匹拉韦在治疗冠状病毒感染方面的应用 |
| CN111265532A (zh) * | 2020-01-21 | 2020-06-12 | 中国人民解放军军事科学院军事医学研究院 | 取代氨基丙酸酯类化合物在治疗2019-nCoV感染中的应用 |
| CN118766947A (zh) * | 2020-01-27 | 2024-10-15 | 吉利德科学公司 | 用于治疗SARS CoV-2感染的方法 |
| WO2021183750A2 (en) | 2020-03-12 | 2021-09-16 | Gilead Sciences, Inc. | Methods of preparing 1'-cyano nucleosides |
| KR20220164784A (ko) | 2020-04-06 | 2022-12-13 | 길리애드 사이언시즈, 인코포레이티드 | 1'-시아노 치환된 카르바뉴클레오시드 유사체의 흡입 제형 |
| CN115666570A (zh) | 2020-05-29 | 2023-01-31 | 吉利德科学公司 | 瑞德西韦治疗方法 |
| EP4172160A2 (en) | 2020-06-24 | 2023-05-03 | Gilead Sciences, Inc. | 1'-cyano nucleoside analogs and uses thereof |
| CA3190702A1 (en) | 2020-08-27 | 2022-03-03 | Elaine Bunyan | Compounds and methods for treatment of viral infections |
| CN112142810A (zh) * | 2020-09-29 | 2020-12-29 | 佛山科学技术学院 | 核苷酸双氨基磷酸酯化合物、其药物组合物及其制备方法和应用 |
| CN112300236A (zh) * | 2020-10-21 | 2021-02-02 | 佛山科学技术学院 | 核苷酸混合氨基磷酸酯化合物、其药物组合物及其应用 |
| TW202400185A (zh) | 2022-03-02 | 2024-01-01 | 美商基利科學股份有限公司 | 用於治療病毒感染的化合物及方法 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR112018005048B8 (pt) * | 2015-09-16 | 2021-03-23 | Gilead Sciences Inc | uso de um composto antiviral ou sal do mesmo para o tratamento de uma infecção por coronaviridae |
| ES2938859T3 (es) * | 2017-05-01 | 2023-04-17 | Gilead Sciences Inc | Una forma cristalina de (S)-2-etilbutilo 2-(((S)-(((2R,3S,4R,5R)-5-(4-aminopirrolo[2,1-f][1,2,4]triazin-7-il)-5-ciano-3,4-dihidroxitetrahidrofuran-2-il)metoxi)(fenoxi)fosforil)amino)propanoato |
| CN111265532A (zh) * | 2020-01-21 | 2020-06-12 | 中国人民解放军军事科学院军事医学研究院 | 取代氨基丙酸酯类化合物在治疗2019-nCoV感染中的应用 |
-
2020
- 2020-01-21 CN CN202010071087.7A patent/CN111265532A/zh active Pending
- 2020-06-22 CN CN202010573430.8A patent/CN111494396B/zh active Active
- 2020-06-22 WO PCT/CN2020/097421 patent/WO2021147236A1/zh active Application Filing
- 2020-10-13 EA EA202092169A patent/EA202092169A1/ru unknown
- 2020-10-13 TW TW109135327A patent/TWI805952B/zh active
- 2020-10-14 US US17/070,271 patent/US20210220377A1/en not_active Abandoned
- 2020-10-14 JP JP2020172950A patent/JP2021116295A/ja active Pending
- 2020-10-16 EP EP20202229.9A patent/EP3854403A1/en active Pending
-
2021
- 2021-01-21 UY UY0001039029A patent/UY39029A/es unknown
- 2021-07-16 US US17/378,415 patent/US20210346411A1/en active Pending
-
2023
- 2023-11-01 JP JP2023187635A patent/JP2024020274A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| US20210220377A1 (en) | 2021-07-22 |
| JP2024020274A (ja) | 2024-02-14 |
| TW202128186A (zh) | 2021-08-01 |
| WO2021147236A9 (zh) | 2021-09-16 |
| CN111494396A (zh) | 2020-08-07 |
| CN111494396B (zh) | 2021-06-15 |
| WO2021147236A1 (zh) | 2021-07-29 |
| CN111265532A (zh) | 2020-06-12 |
| TWI805952B (zh) | 2023-06-21 |
| EA202092169A1 (ru) | 2021-07-30 |
| JP2021116295A (ja) | 2021-08-10 |
| US20210346411A1 (en) | 2021-11-11 |
| EP3854403A1 (en) | 2021-07-28 |
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