UY38585A - Gonadotropina coriónica equina recombinant (recg) biológicamente activa y proceso para obtenerla, composición veterinaria y uso - Google Patents

Gonadotropina coriónica equina recombinant (recg) biológicamente activa y proceso para obtenerla, composición veterinaria y uso

Info

Publication number
UY38585A
UY38585A UY0001038585A UY38585A UY38585A UY 38585 A UY38585 A UY 38585A UY 0001038585 A UY0001038585 A UY 0001038585A UY 38585 A UY38585 A UY 38585A UY 38585 A UY38585 A UY 38585A
Authority
UY
Uruguay
Prior art keywords
recg
biologically active
veterinary
chorionic gonadotropin
present
Prior art date
Application number
UY0001038585A
Other languages
English (en)
Inventor
Cleide Sogayar Mari
Cláudia Oliveira Carreira Nishiyama Ana
Angelo Almeida Demasi Marcos
Lauren Camargo
Maldonado Coelho Tatiane
Original Assignee
Ouro Fino Saude Animal Participacoes S A
Univ Sao Paulo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ouro Fino Saude Animal Participacoes S A, Univ Sao Paulo filed Critical Ouro Fino Saude Animal Participacoes S A
Publication of UY38585A publication Critical patent/UY38585A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/34—Gestagens
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/59—Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g.hCG [human chorionic gonadotropin]; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/64—General methods for preparing the vector, for introducing it into the cell or for selecting the vector-containing host
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2227/00—Animals characterised by species
    • A01K2227/10—Mammal
    • A01K2227/101—Bovine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Endocrinology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Wood Science & Technology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • Reproductive Health (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Physics & Mathematics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Diabetes (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)

Abstract

La presente invención se refiere a la producción de una gonadotropina coriónica equina recombinante (reCG) biológicamente activa, a una composición veterinaria que comprende reCG y el uso de reCG o una composición que comprende reCG. La reCG de la presente invención tiene un perfil de glucosilación similar al de las gonadotropinas coriónicas disponibles comercialmente y exhibe un nivel de actividad in vivo correspondiente al eCG y similar al de las hormonas FSH y LH. La presente invención tiene aplicación en el campo de la biotecnología, más específicamente, en el campo de la reproducción asistida veterinaria, siendo especialmente adecuada para el tratamiento de afecciones veterinarias relacionadas con la reproducción y ovulación de mamíferos, así como para la fabricación de kits de diagnóstico o como suplemento para el cultivo celular.
UY0001038585A 2019-02-28 2020-02-13 Gonadotropina coriónica equina recombinant (recg) biológicamente activa y proceso para obtenerla, composición veterinaria y uso UY38585A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
BR102019004147-1A BR102019004147A2 (pt) 2019-02-28 2019-02-28 Gonadotrofina coriônica equina recombinante (recg) biologicamente ativa e processo para obtenção da mesma, composição veterinária e uso

Publications (1)

Publication Number Publication Date
UY38585A true UY38585A (es) 2020-09-30

Family

ID=72238219

Family Applications (1)

Application Number Title Priority Date Filing Date
UY0001038585A UY38585A (es) 2019-02-28 2020-02-13 Gonadotropina coriónica equina recombinant (recg) biológicamente activa y proceso para obtenerla, composición veterinaria y uso

Country Status (5)

Country Link
EP (1) EP3932943A4 (es)
AR (1) AR118209A1 (es)
BR (1) BR102019004147A2 (es)
UY (1) UY38585A (es)
WO (1) WO2020172728A1 (es)

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4840896A (en) 1983-11-02 1989-06-20 Integrated Genetics, Inc. Heteropolymeric protein
US5047335A (en) 1988-12-21 1991-09-10 The Regents Of The University Of Calif. Process for controlling intracellular glycosylation of proteins
US6238890B1 (en) 1994-02-18 2001-05-29 Washington University Single chain forms of the glycoprotein hormone quartet
ES2251731T3 (es) 1994-02-18 2006-05-01 Washington University Gonadotropina monocatenaria.
JPH1036285A (ja) * 1996-07-23 1998-02-10 Denki Kagaku Kogyo Kk 新規な性腺刺激ホルモン及びその製造方法
JPH1036398A (ja) * 1996-07-25 1998-02-10 Denki Kagaku Kogyo Kk 性腺刺激ホルモンの製造法
EP0974599A4 (en) 1996-11-12 2002-06-12 Teikoku Hormone Mfg Co Ltd EQUINE, SINGLE-STRANDED AND RECOMBINANT CHORIONIC GONADOTROPHIN
US6103501A (en) 1997-11-17 2000-08-15 Washington University Single chain glycoprotein hormones comprising two β and one α subunits and recombinant production thereof
US6987172B2 (en) 2001-03-05 2006-01-17 Washington University In St. Louis Multifunctional single chain glycoprotein hormones comprising three or more β subunits
WO2009073574A1 (en) 2007-11-30 2009-06-11 Aspenbio Pharma, Inc. Activity of recombinant equine follicle stimulating hormone
BR112015028737B1 (pt) * 2013-05-16 2022-05-10 Universidade De São Paulo - Usp Métodos para a produção e/ou purificação de hormônios
WO2016178087A1 (en) 2015-05-04 2016-11-10 Biosourcing Sa Transgenic production of chorionic gonadotropin
BR102015032660B1 (pt) * 2015-12-28 2019-05-28 Ouro Fino Saúde Animal Participações S.A. PROCESSO DE PRODUÇÃO DE UMA GONADOTROFINA CORIÔNICA EQUINA RECOMBINANTE (reCG): COMPOSIÇÃO VETERINÁRIA E USO
EP3398609A4 (en) * 2015-12-28 2019-05-08 Ouro Fino Saúde Animal Participações S.A. PROCESS FOR THE PRODUCTION OF RECOMBINANT EQUINE CHORIONIC CHRONIC GONADOTROPHIN (RECG), VETERINARY COMPOSITION AND USE
BR102016006222A2 (pt) * 2016-03-22 2017-09-26 Universidade De São Paulo - Usp Process of production and purification of recombinant hydrogen hydrogen hybrid or non-hybrid, recombinant hydrogen hydrogen hybrids or non-hybrid, vectors of expression, and uses of recombinant glicoprotetic hormones

Also Published As

Publication number Publication date
EP3932943A4 (en) 2022-11-09
BR102019004147A2 (pt) 2020-10-06
EP3932943A1 (en) 2022-01-05
WO2020172728A1 (pt) 2020-09-03
AR118209A1 (es) 2021-09-22

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