UY37013A - 2-fenil-3-(piperazinometil)imidazopiridinas sustituidas y su uso - Google Patents

2-fenil-3-(piperazinometil)imidazopiridinas sustituidas y su uso

Info

Publication number
UY37013A
UY37013A UY0001037013A UY37013A UY37013A UY 37013 A UY37013 A UY 37013A UY 0001037013 A UY0001037013 A UY 0001037013A UY 37013 A UY37013 A UY 37013A UY 37013 A UY37013 A UY 37013A
Authority
UY
Uruguay
Prior art keywords
phenyl
piperazinometil
imidazopiridinas
replaced
prevention
Prior art date
Application number
UY0001037013A
Other languages
English (en)
Inventor
Klemens Lustig Dr
Heinrich Meier Dr
Johanna Mosig Dr
Luisella Toschi Dr
Udo Albus Dr
Doris Gehring
Rosenstein Bjöm
Thomas Müller Dr
Michael Hahn Dr
Martina Delbeck Dr
Original Assignee
Bayer Pharma AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Pharma AG filed Critical Bayer Pharma AG
Publication of UY37013A publication Critical patent/UY37013A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/16—Central respiratory analeptics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pulmonology (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

La presente solicitud se refiere a derivados novedosos de 2-fenil-3-(piperazinometil)imidazo[1,2-a]piridina, a los procesos para prepararlos, a su uso por sí solos o en combinaciones para el tratamiento y/o prevención de enfermedades y a su uso para preparar medicamentos para el tratamiento y/o la prevención de trastornos respiratorios, tales como, trastornos respiratorios relacionados con el sueño, tales como apneas obstructivas del sueño y apneas centrales del sueño y ronquidos.
UY0001037013A 2015-12-10 2016-12-09 2-fenil-3-(piperazinometil)imidazopiridinas sustituidas y su uso UY37013A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP15199270 2015-12-10
EP16196836 2016-11-02

Publications (1)

Publication Number Publication Date
UY37013A true UY37013A (es) 2017-06-30

Family

ID=57517877

Family Applications (1)

Application Number Title Priority Date Filing Date
UY0001037013A UY37013A (es) 2015-12-10 2016-12-09 2-fenil-3-(piperazinometil)imidazopiridinas sustituidas y su uso

Country Status (26)

Country Link
US (1) US10759794B2 (es)
EP (1) EP3386979B1 (es)
JP (1) JP2018536693A (es)
KR (1) KR20180088462A (es)
CN (1) CN108290887A (es)
AU (1) AU2016365676A1 (es)
BR (1) BR112018011783A2 (es)
CA (1) CA3007724C (es)
CL (1) CL2018001511A1 (es)
CO (1) CO2018005905A2 (es)
CU (1) CU20180056A7 (es)
DO (1) DOP2018000142A (es)
EA (1) EA201891374A1 (es)
EC (1) ECSP18043573A (es)
GE (1) GEP20207104B (es)
HK (1) HK1254853A1 (es)
IL (1) IL259374A (es)
MX (1) MX2018007040A (es)
NI (1) NI201800066A (es)
PH (1) PH12018501235A1 (es)
SG (1) SG11201804449WA (es)
SV (1) SV2018005704A (es)
TN (1) TN2018000193A1 (es)
TW (1) TW201734012A (es)
UY (1) UY37013A (es)
WO (1) WO2017097792A1 (es)

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CA3007699A1 (en) 2015-12-10 2017-06-15 Bayer Pharma Aktiengesellschaft Substituted perhydropyrrolo[3,4-c]pyrrole derivatives and the use of same
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WO2018227427A1 (en) 2017-06-14 2018-12-20 Bayer Aktiengesellschaft Substituted bridged diazepane derivatives and use thereof
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TW202342045A (zh) 2021-12-22 2023-11-01 德商拜耳廠股份有限公司 用於治療睡眠呼吸中止之ｔａｓｋ１／３通道阻斷劑與ｐ２ｘ３受體拮抗劑之組合
TW202342052A (zh) 2021-12-22 2023-11-01 德商拜耳廠股份有限公司 用於治療睡眠呼吸中止之ｔａｓｋ１／３通道阻斷劑與正腎上腺素再吸收抑制劑之組合
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WO2023131638A1 (en) 2022-01-07 2023-07-13 Bayer Aktiengesellschaft 2,3-dihydrobenzo [b][1, 4]dioxin-2-ylmethyl)piperazin-1-yl derivates for the treatment of sleep apnea
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Also Published As

Publication number Publication date
NI201800066A (es) 2019-03-14
US10759794B2 (en) 2020-09-01
CA3007724C (en) 2023-10-17
TN2018000193A1 (en) 2019-10-04
CN108290887A (zh) 2018-07-17
MX2018007040A (es) 2018-08-15
PH12018501235A1 (en) 2019-02-04
CO2018005905A2 (es) 2018-07-10
CA3007724A1 (en) 2017-06-15
EA201891374A1 (ru) 2018-11-30
SG11201804449WA (en) 2018-06-28
TW201734012A (zh) 2017-10-01
CL2018001511A1 (es) 2018-09-21
EP3386979B1 (de) 2020-07-29
US20190062326A1 (en) 2019-02-28
HK1254853A1 (zh) 2019-07-26
CU20180056A7 (es) 2018-10-04
GEAP202014824A (en) 2020-01-27
ECSP18043573A (es) 2018-06-30
JP2018536693A (ja) 2018-12-13
GEP20207104B (en) 2020-05-11
IL259374A (en) 2018-07-31
KR20180088462A (ko) 2018-08-03
WO2017097792A1 (de) 2017-06-15
BR112018011783A2 (pt) 2018-12-04
SV2018005704A (es) 2018-09-10
EP3386979A1 (de) 2018-10-17
DOP2018000142A (es) 2018-06-30
AU2016365676A1 (en) 2018-06-07

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