UY36651A - Compuestos antiestrogénicos - Google Patents
Compuestos antiestrogénicosInfo
- Publication number
- UY36651A UY36651A UY0001036651A UY36651A UY36651A UY 36651 A UY36651 A UY 36651A UY 0001036651 A UY0001036651 A UY 0001036651A UY 36651 A UY36651 A UY 36651A UY 36651 A UY36651 A UY 36651A
- Authority
- UY
- Uruguay
- Prior art keywords
- compounds
- antiestrogenic compounds
- disorders
- present
- antiestrogenic
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/12—Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/30—Oestrogens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/32—Antioestrogens
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/10—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing aromatic rings
Abstract
La presente descripción proporciona un compuesto de la fórmula I:o una sal farmacéuticamente aceptable, en donde X, R1-R8, Y1-Y5, m, n, p y q se definen en la presente. Los nuevos compuestos de 2H-cromeno son de utilidad para la modulación de trastornos mediados por estrógeno y otros trastornos, como se describen en la presente. La presente invención también se refiere a composiciones farmacéuticas con contenido de los compuestos y a métodos de uso de los compuestos y las composiciones.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201562153097P | 2015-04-27 | 2015-04-27 |
Publications (1)
Publication Number | Publication Date |
---|---|
UY36651A true UY36651A (es) | 2016-11-30 |
Family
ID=55863140
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
UY0001036651A UY36651A (es) | 2015-04-27 | 2016-04-25 | Compuestos antiestrogénicos |
Country Status (6)
Country | Link |
---|---|
US (2) | US20160311805A1 (es) |
AR (1) | AR104415A1 (es) |
CA (1) | CA2928060A1 (es) |
TW (1) | TW201710253A (es) |
UY (1) | UY36651A (es) |
WO (1) | WO2016174551A1 (es) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BR112018006121B1 (pt) | 2015-10-01 | 2024-01-23 | Olema Pharmaceuticals, Inc | COMPOSTOS DE TETRA-HIDRO-1H-PIRIDO[3,4-b]INDOL, COMPOSIÇÕES COMPREENDENDO OS REFERIDOS COMPOSTOS E USOS DOS MESMOS |
WO2017100715A1 (en) | 2015-12-09 | 2017-06-15 | The Board Of Trustees Of The University Of Illinois | Benzothiophene-based selective estrogen receptor downregulator compounds |
WO2017182493A1 (en) | 2016-04-20 | 2017-10-26 | Astrazeneca Ab | Indazole derivatives for use in down-regulation of the estrogen receptor for the treatment of cancer |
US10149839B2 (en) | 2016-07-25 | 2018-12-11 | Astrazeneca Ab | Chemical compounds |
UA125824C2 (uk) | 2016-10-24 | 2022-06-15 | Астразенека Аб | 6,7,8,9-ТЕТРАГІДРО-3H-ПІРАЗОЛО[4,3-f]ІЗОХІНОЛІНОВІ ПОХІДНІ, ЗАСТОСОВНІ В ЛІКУВАННІ РАКУ |
EA201991622A1 (ru) | 2017-01-06 | 2020-01-23 | Г1 Терапьютикс, Инк. | Комплексная терапия для лечения рака |
WO2018138739A1 (en) | 2017-01-27 | 2018-08-02 | Sun Pharma Advanced Research Company Limited | Novel antiestrogenic heterocyclic compounds |
MA52555A (fr) | 2017-01-30 | 2021-03-17 | Astrazeneca Ab | Modulateurs du récepteur des oestrogènes |
CA3089298A1 (en) * | 2018-01-22 | 2019-07-25 | Radius Pharmaceuticals, Inc. | Estrogen receptor-modulating compounds |
WO2020163637A1 (en) * | 2019-02-06 | 2020-08-13 | Oregon Health & Science University | Bisphosphonate-linked compounds |
US11014915B2 (en) | 2019-07-22 | 2021-05-25 | Sun Pharma Advanced Research Company Limited | Selective estrogen receptor degrader |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2586908T3 (es) * | 2010-12-24 | 2016-10-19 | Merck Sharp & Dohme B.V. | Derivados de azetidina N-sustituidos |
MX2015016171A (es) * | 2013-06-19 | 2016-08-08 | Seragon Pharmaceuticals Inc | Moduladores del receptor de estrogeno de azetidina y usos de los mismos. |
-
2016
- 2016-04-21 WO PCT/IB2016/052249 patent/WO2016174551A1/en active Application Filing
- 2016-04-22 US US15/135,840 patent/US20160311805A1/en not_active Abandoned
- 2016-04-22 TW TW105112622A patent/TW201710253A/zh unknown
- 2016-04-22 CA CA2928060A patent/CA2928060A1/en not_active Abandoned
- 2016-04-25 UY UY0001036651A patent/UY36651A/es not_active Application Discontinuation
- 2016-04-26 AR ARP160101179A patent/AR104415A1/es unknown
-
2017
- 2017-08-14 US US15/676,400 patent/US20170362210A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
CA2928060A1 (en) | 2016-10-27 |
US20170362210A1 (en) | 2017-12-21 |
US20160311805A1 (en) | 2016-10-27 |
WO2016174551A1 (en) | 2016-11-03 |
AR104415A1 (es) | 2017-07-19 |
TW201710253A (zh) | 2017-03-16 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
109 | Application deemed to be withdrawn |
Effective date: 20221114 |