UY30783A1 - Derivados de sulfonil-fenil-2h-[1,2,4]oxadiazol-5-ona, procesos para su preparacion y su uso como agentes farmacéuticos - Google Patents
Derivados de sulfonil-fenil-2h-[1,2,4]oxadiazol-5-ona, procesos para su preparacion y su uso como agentes farmacéuticosInfo
- Publication number
- UY30783A1 UY30783A1 UY30783A UY30783A UY30783A1 UY 30783 A1 UY30783 A1 UY 30783A1 UY 30783 A UY30783 A UY 30783A UY 30783 A UY30783 A UY 30783A UY 30783 A1 UY30783 A1 UY 30783A1
- Authority
- UY
- Uruguay
- Prior art keywords
- derivatives
- oxadiazol
- sulfonil
- fenil
- ona
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4245—Oxadiazoles
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/472—Non-condensed isoquinolines, e.g. papaverine
- A61K31/4725—Non-condensed isoquinolines, e.g. papaverine containing further heterocyclic rings
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
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- A—HUMAN NECESSITIES
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- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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- A—HUMAN NECESSITIES
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- A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
- A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Diabetes (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Dermatology (AREA)
- Cardiology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Heart & Thoracic Surgery (AREA)
- Rheumatology (AREA)
- Endocrinology (AREA)
- Pain & Pain Management (AREA)
- Pulmonology (AREA)
- Oncology (AREA)
- Vascular Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Epidemiology (AREA)
- Physical Education & Sports Medicine (AREA)
- Immunology (AREA)
- Psychology (AREA)
- Reproductive Health (AREA)
- Psychiatry (AREA)
- Ophthalmology & Optometry (AREA)
- Emergency Medicine (AREA)
- Virology (AREA)
Abstract
Derivados de sulfoniel-fenil-2H-[1,2,4]oxadiazol-5-ona, y sus sales fisiologicamente aceptables y derivados fisiologicamente funcionales con actividad agonista de PPARdelta o PPARdelta y PPARgamma. Lo que se describe son compuestos de la formula (I), Estos compuestos son adecuados para el tratamiento y/o prevencion de trastornos de metabolismo de ácidos grasoso y trastornos de utilizacion de la glucosa, así como de resistencia a la insulina, la desmielinizacion y neurodegenerativos del sistema nervioso central y periférico.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP06025880A EP1932843A1 (en) | 2006-12-14 | 2006-12-14 | Sulfonyl-phenyl-2H-(1,2,4) oxadiazole-5-one derivatives, processes for their preparation and their use as pharmaceuticals |
Publications (1)
Publication Number | Publication Date |
---|---|
UY30783A1 true UY30783A1 (es) | 2008-07-31 |
Family
ID=37998695
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
UY30783A UY30783A1 (es) | 2006-12-14 | 2007-12-12 | Derivados de sulfonil-fenil-2h-[1,2,4]oxadiazol-5-ona, procesos para su preparacion y su uso como agentes farmacéuticos |
Country Status (24)
Country | Link |
---|---|
US (1) | US8173674B2 (es) |
EP (2) | EP1932843A1 (es) |
JP (1) | JP2010512352A (es) |
KR (1) | KR20090087922A (es) |
CN (1) | CN101558064A (es) |
AR (1) | AR064299A1 (es) |
AU (1) | AU2007331805A1 (es) |
BR (1) | BRPI0720416A2 (es) |
CA (1) | CA2672347A1 (es) |
CL (1) | CL2007003614A1 (es) |
CO (1) | CO6210729A2 (es) |
CR (1) | CR10778A (es) |
EC (1) | ECSP099409A (es) |
MA (1) | MA30981B1 (es) |
MX (1) | MX2009005535A (es) |
NO (1) | NO20092293L (es) |
PE (1) | PE20081404A1 (es) |
RU (1) | RU2009126745A (es) |
SV (1) | SV2009003293A (es) |
TN (1) | TN2009000242A1 (es) |
TW (1) | TW200843749A (es) |
UY (1) | UY30783A1 (es) |
WO (1) | WO2008071311A1 (es) |
ZA (1) | ZA200903160B (es) |
Families Citing this family (33)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2010000353A1 (en) * | 2008-06-09 | 2010-01-07 | Sanofi-Aventis | Sulfonamides with heterocycle and oxadiazolone headgroup, processes for their preparation and their use as pharmaceuticals |
JP2011523664A (ja) | 2008-06-09 | 2011-08-18 | サノフィ−アベンティス | オキサジアゾロン頭部基を有する、環付加された(annelated)N−複素環式スルホンアミド、それらの製造方法および医薬としてのそれらの使用 |
WO2011107494A1 (de) | 2010-03-03 | 2011-09-09 | Sanofi | Neue aromatische glykosidderivate, diese verbindungen enthaltende arzneimittel und deren verwendung |
EP2582709B1 (de) | 2010-06-18 | 2018-01-24 | Sanofi | Azolopyridin-3-on-derivate als inhibitoren von lipasen und phospholipasen |
US8530413B2 (en) | 2010-06-21 | 2013-09-10 | Sanofi | Heterocyclically substituted methoxyphenyl derivatives with an oxo group, processes for preparation thereof and use thereof as medicaments |
TW201215387A (en) | 2010-07-05 | 2012-04-16 | Sanofi Aventis | Spirocyclically substituted 1,3-propane dioxide derivatives, processes for preparation thereof and use thereof as a medicament |
TW201221505A (en) | 2010-07-05 | 2012-06-01 | Sanofi Sa | Aryloxyalkylene-substituted hydroxyphenylhexynoic acids, process for preparation thereof and use thereof as a medicament |
TW201215388A (en) | 2010-07-05 | 2012-04-16 | Sanofi Sa | (2-aryloxyacetylamino)phenylpropionic acid derivatives, processes for preparation thereof and use thereof as medicaments |
WO2013037390A1 (en) | 2011-09-12 | 2013-03-21 | Sanofi | 6-(4-hydroxy-phenyl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors |
EP2760862B1 (en) | 2011-09-27 | 2015-10-21 | Sanofi | 6-(4-hydroxy-phenyl)-3-alkyl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors |
US8859774B2 (en) | 2012-05-25 | 2014-10-14 | Corcept Therapeutics, Inc. | Heteroaryl-ketone fused azadecalin glucocorticoid receptor modulators |
PL3590517T3 (pl) * | 2012-05-25 | 2021-09-20 | Corcept Therapeutics Incorporated | Modulatory receptorów glukokortykoidowych typu azadekaliny skondensowanej z heteroaryloketonem |
US20190135798A1 (en) | 2015-11-02 | 2019-05-09 | Basf Se | Substituted Oxadiazoles for Combating Phytopathogenic Fungi |
EP3165094A1 (en) | 2015-11-03 | 2017-05-10 | Basf Se | Substituted oxadiazoles for combating phytopathogenic fungi |
US20180317490A1 (en) | 2015-11-04 | 2018-11-08 | Basf Se | Substituted oxadiazoles for combating phytopathogenic fungi |
JP2019502661A (ja) | 2015-11-19 | 2019-01-31 | ビーエーエスエフ ソシエタス・ヨーロピアBasf Se | 植物病原菌を駆除するための置換オキサジアゾール |
JP2018537457A (ja) | 2015-11-19 | 2018-12-20 | ビーエーエスエフ ソシエタス・ヨーロピアBasf Se | 植物病原菌を駆除するための置換オキサジアゾール |
EP3442951A1 (en) | 2016-04-11 | 2019-02-20 | Basf Se | Substituted oxadiazoles for combating phytopathogenic fungi |
WO2017211650A1 (en) | 2016-06-09 | 2017-12-14 | Basf Se | Substituted oxadiazoles for combating phytopathogenic fungi |
WO2017211652A1 (en) | 2016-06-09 | 2017-12-14 | Basf Se | Substituted oxadiazoles for combating phytopathogenic fungi |
WO2018114393A1 (en) | 2016-12-19 | 2018-06-28 | Basf Se | Substituted oxadiazoles for combating phytopathogenic fungi |
EP3339297A1 (en) | 2016-12-20 | 2018-06-27 | Basf Se | Substituted oxadiazoles for combating phytopathogenic fungi |
JP2020515563A (ja) | 2017-03-31 | 2020-05-28 | コーセプト セラピューティクス, インコーポレイテッド | 子宮頸がんを処置するためのグルココルチコイドレセプターモジュレーター |
WO2018219797A1 (en) | 2017-06-02 | 2018-12-06 | Basf Se | Substituted oxadiazoles for combating phytopathogenic fungi |
US20200190043A1 (en) | 2017-06-19 | 2020-06-18 | Basf Se | 2-[[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]aryloxy](thio)acetamides for combating phytopathogenic fungi |
WO2019002158A1 (en) | 2017-06-30 | 2019-01-03 | Basf Se | SUBSTITUTED TRIFLUOROMETHYLOXADIAZOLES FOR THE CONTROL OF PHYTOPATHOGENIC FUNGI |
WO2019052932A1 (en) | 2017-09-18 | 2019-03-21 | Basf Se | SUBSTITUTED TRIFLUOROMETHYLOXADIAZOLES FOR COMBATING PHYTOPATHOGENIC FUNGI |
EP3713936B1 (en) | 2017-11-23 | 2021-10-20 | Basf Se | Substituted trifluoromethyloxadiazoles for combating phytopathogenic fungi |
WO2020132046A1 (en) | 2018-12-19 | 2020-06-25 | Corcept Therapeutics Incorporated | Methods of treating cancer comprising administration of a glucocorticoid receptor modulator and a cancer chemotherapy agent |
NZ776354A (en) | 2018-12-19 | 2023-03-31 | Corcept Therapeutics Inc | Pharmaceutical formulations containing relacorilant, a heteroaryl-ketone fused azadecalin compound |
US11234971B2 (en) | 2018-12-19 | 2022-02-01 | Corcept Therapeutics Incorporated | Methods of treating cancer comprising administration of a glucocorticoid receptor modulator and a cancer chemotherapy agent |
US11058670B2 (en) | 2019-02-22 | 2021-07-13 | Corcept Therapeutics Incorporated | Therapeutic uses of relacorilant, a heteroaryl-ketone fused azadecalin glucocorticoid receptor modulator |
KR102649355B1 (ko) * | 2020-03-31 | 2024-03-19 | 주식회사 엘지화학 | 췌도 이식 보호용 조성물 |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5641796A (en) * | 1994-11-01 | 1997-06-24 | Eli Lilly And Company | Oral hypoglycemic agents |
DE10222034A1 (de) * | 2002-05-17 | 2003-11-27 | Bayer Ag | Tetrahydroisochinolin-Derivate |
DE10229777A1 (de) * | 2002-07-03 | 2004-01-29 | Bayer Ag | Indolin-Phenylsulfonamid-Derivate |
US20070105959A1 (en) * | 2003-03-11 | 2007-05-10 | Shinya Kusuda | Cynnamyl alcohol derivative compounds and drugs containing the compounds as active ingredient |
US20060258683A1 (en) | 2003-04-07 | 2006-11-16 | Liu Kevin | Para-sulfonyl substituted phenyl compounds as modulators of ppars |
DE10335449A1 (de) | 2003-08-02 | 2005-02-17 | Bayer Healthcare Ag | Bicyclische Indolinsulfonamid-Derivate |
DE602004004631D1 (de) * | 2004-04-01 | 2007-03-22 | Sanofi Aventis Deutschland | Oxadiazolone, Verfahren zu ihrer Herstellung sowie ihre Verwendung als Pharmazeutika |
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2006
- 2006-12-14 EP EP06025880A patent/EP1932843A1/en not_active Withdrawn
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2007
- 2007-11-30 RU RU2009126745/04A patent/RU2009126745A/ru not_active Application Discontinuation
- 2007-11-30 AU AU2007331805A patent/AU2007331805A1/en not_active Abandoned
- 2007-11-30 KR KR1020097012309A patent/KR20090087922A/ko not_active Application Discontinuation
- 2007-11-30 WO PCT/EP2007/010390 patent/WO2008071311A1/en active Application Filing
- 2007-11-30 CN CNA2007800454445A patent/CN101558064A/zh active Pending
- 2007-11-30 JP JP2009540626A patent/JP2010512352A/ja not_active Abandoned
- 2007-11-30 BR BRPI0720416-7A patent/BRPI0720416A2/pt not_active IP Right Cessation
- 2007-11-30 CA CA002672347A patent/CA2672347A1/en not_active Abandoned
- 2007-11-30 EP EP07846915.2A patent/EP2102198B1/en active Active
- 2007-11-30 MX MX2009005535A patent/MX2009005535A/es not_active Application Discontinuation
- 2007-12-12 UY UY30783A patent/UY30783A1/es not_active Application Discontinuation
- 2007-12-12 CL CL200703614A patent/CL2007003614A1/es unknown
- 2007-12-12 TW TW096147333A patent/TW200843749A/zh unknown
- 2007-12-12 AR ARP070105563A patent/AR064299A1/es not_active Application Discontinuation
- 2007-12-12 PE PE2007001772A patent/PE20081404A1/es not_active Application Discontinuation
-
2009
- 2009-05-07 ZA ZA200903160A patent/ZA200903160B/xx unknown
- 2009-05-07 CR CR10778A patent/CR10778A/es not_active Application Discontinuation
- 2009-06-05 CO CO09058528A patent/CO6210729A2/es not_active Application Discontinuation
- 2009-06-09 US US12/480,974 patent/US8173674B2/en not_active Expired - Fee Related
- 2009-06-10 MA MA31971A patent/MA30981B1/fr unknown
- 2009-06-10 SV SV2009003293A patent/SV2009003293A/es unknown
- 2009-06-12 EC EC2009009409A patent/ECSP099409A/es unknown
- 2009-06-12 TN TNP2009000242A patent/TN2009000242A1/fr unknown
- 2009-06-15 NO NO20092293A patent/NO20092293L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
EP2102198A1 (en) | 2009-09-23 |
BRPI0720416A2 (pt) | 2013-12-31 |
WO2008071311A1 (en) | 2008-06-19 |
US8173674B2 (en) | 2012-05-08 |
MX2009005535A (es) | 2009-06-05 |
PE20081404A1 (es) | 2008-11-04 |
MA30981B1 (fr) | 2009-12-01 |
AR064299A1 (es) | 2009-03-25 |
RU2009126745A (ru) | 2011-01-20 |
CR10778A (es) | 2009-06-24 |
CN101558064A (zh) | 2009-10-14 |
CL2007003614A1 (es) | 2008-06-20 |
KR20090087922A (ko) | 2009-08-18 |
NO20092293L (no) | 2009-09-08 |
ECSP099409A (es) | 2009-07-31 |
EP1932843A1 (en) | 2008-06-18 |
AU2007331805A1 (en) | 2008-06-19 |
TW200843749A (en) | 2008-11-16 |
SV2009003293A (es) | 2009-10-27 |
EP2102198B1 (en) | 2015-02-25 |
US20090298871A1 (en) | 2009-12-03 |
CA2672347A1 (en) | 2008-06-19 |
CO6210729A2 (es) | 2010-10-20 |
TN2009000242A1 (en) | 2010-10-18 |
JP2010512352A (ja) | 2010-04-22 |
ZA200903160B (en) | 2010-10-27 |
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