UY28884A1 - Derivados de benceno halogenados sustituidos con trímeros macrocíclicos - Google Patents

Derivados de benceno halogenados sustituidos con trímeros macrocíclicos

Info

Publication number
UY28884A1
UY28884A1 UY28884A UY28884A UY28884A1 UY 28884 A1 UY28884 A1 UY 28884A1 UY 28884 A UY28884 A UY 28884A UY 28884 A UY28884 A UY 28884A UY 28884 A1 UY28884 A1 UY 28884A1
Authority
UY
Uruguay
Prior art keywords
benchen
trimmers
macrocyclic
halogenated
derivatives replaced
Prior art date
Application number
UY28884A
Other languages
English (en)
Inventor
Johannes Platzek
Juan R Harto
Jose L Martin
Heiko Schirmer
Hanns-Joachim Weinmann
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Publication of UY28884A1 publication Critical patent/UY28884A1/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/0002General or multifunctional contrast agents, e.g. chelated agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/04X-ray contrast preparations
    • A61K49/0433X-ray contrast preparations containing an organic halogenated X-ray contrast-enhancing agent
    • A61K49/0438Organic X-ray contrast-enhancing agent comprising an iodinated group or an iodine atom, e.g. iopamidol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/06Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/085Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier conjugated systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/06Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/10Organic compounds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D257/00Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
    • C07D257/02Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Cosmetics (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Complejos metálicos de la fórmula general I donde Hal es bromo o yodo y A1 y A2 tienen significado diferente, que son apropiados como medios de contraste.
UY28884A 2004-05-05 2005-05-04 Derivados de benceno halogenados sustituidos con trímeros macrocíclicos UY28884A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE102004023093A DE102004023093B3 (de) 2004-05-05 2004-05-05 Trimere makrocyclisch substituierte Halogen-Benzolderivate

Publications (1)

Publication Number Publication Date
UY28884A1 true UY28884A1 (es) 2005-11-30

Family

ID=34967980

Family Applications (1)

Application Number Title Priority Date Filing Date
UY28884A UY28884A1 (es) 2004-05-05 2005-05-04 Derivados de benceno halogenados sustituidos con trímeros macrocíclicos

Country Status (18)

Country Link
US (1) US7385054B2 (es)
EP (1) EP1742926B1 (es)
JP (1) JP2007536295A (es)
AR (1) AR050984A1 (es)
AT (1) ATE369347T1 (es)
DE (2) DE102004023093B3 (es)
DK (1) DK1742926T3 (es)
ES (1) ES2289711T3 (es)
GT (1) GT200500106A (es)
PA (1) PA8632101A1 (es)
PE (1) PE20060350A1 (es)
PL (1) PL1742926T3 (es)
PT (1) PT1742926E (es)
SI (1) SI1742926T1 (es)
SV (1) SV2006002104A (es)
TW (1) TW200539894A (es)
UY (1) UY28884A1 (es)
WO (1) WO2005108379A1 (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102007058220A1 (de) 2007-12-03 2009-06-04 Bayer Schering Pharma Aktiengesellschaft Dimere macrocyclisch substituierte Benzolderivate
KR101209633B1 (ko) * 2009-09-09 2012-12-06 주식회사 휴메딕스 페길레이션된 삼요오드화 아릴 화합물 및 그를 포함하는 x-선 조영제
EP3101012A1 (en) 2015-06-04 2016-12-07 Bayer Pharma Aktiengesellschaft New gadolinium chelate compounds for use in magnetic resonance imaging
CA3044877A1 (en) 2016-11-28 2018-05-31 Bayer Pharma Aktiengesellschaft High relaxivity gadolinium chelate compounds for use in magnetic resonance imaging
BR112021007707A2 (pt) 2018-11-23 2021-07-27 Bayer Aktiengesellschaft formulação de meios de contraste e processo de preparação da mesma

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5324503A (en) * 1992-02-06 1994-06-28 Mallinckrodt Medical, Inc. Iodo-phenylated chelates for x-ray contrast
WO1994027644A1 (en) * 1993-06-02 1994-12-08 Bracco S.P.A. Iodinated paramagnetic chelates, and their use as contrast agents
US7208140B2 (en) 2003-02-19 2007-04-24 Schering Aktiengesellschaft Trimeric macrocyclic substituted benzene derivatives
DE10307759B3 (de) * 2003-02-19 2004-11-18 Schering Ag Trimere makrocyclisch substituierte Benzolderivate, deren Herstellung und Verwendung als Kontrastmittel sowie diese enthaltende pharmazeutische Mittel

Also Published As

Publication number Publication date
SV2006002104A (es) 2006-02-15
US7385054B2 (en) 2008-06-10
PA8632101A1 (es) 2006-07-03
AR050984A1 (es) 2006-12-13
DE502005001194D1 (de) 2007-09-20
ATE369347T1 (de) 2007-08-15
ES2289711T3 (es) 2008-02-01
JP2007536295A (ja) 2007-12-13
SI1742926T1 (sl) 2007-12-31
GT200500106A (es) 2005-12-15
US20060154989A1 (en) 2006-07-13
PT1742926E (pt) 2007-09-24
TW200539894A (en) 2005-12-16
WO2005108379A1 (de) 2005-11-17
PL1742926T3 (pl) 2007-12-31
DE102004023093B3 (de) 2006-03-02
EP1742926A1 (de) 2007-01-17
PE20060350A1 (es) 2006-05-25
EP1742926B1 (de) 2007-08-08
DK1742926T3 (da) 2007-10-15

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Legal Events

Date Code Title Description
109 Application deemed to be withdrawn

Effective date: 20160617