PL1742926T3 - Trimeryczne, makrocyklicznie podstawione pochodne fluorowcobenzenu - Google Patents

Trimeryczne, makrocyklicznie podstawione pochodne fluorowcobenzenu

Info

Publication number
PL1742926T3
PL1742926T3 PL05742880T PL05742880T PL1742926T3 PL 1742926 T3 PL1742926 T3 PL 1742926T3 PL 05742880 T PL05742880 T PL 05742880T PL 05742880 T PL05742880 T PL 05742880T PL 1742926 T3 PL1742926 T3 PL 1742926T3
Authority
PL
Poland
Prior art keywords
macrocycle
halogen
trimer
substituted
benzol derivatives
Prior art date
Application number
PL05742880T
Other languages
English (en)
Inventor
Juan R Harto
José L Martin
Johannes Platzek
Heiko Schirmer
Hanns-Joachim Weinmann
Jose Carretero
Original Assignee
Bayer Schering Pharma Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Schering Pharma Ag filed Critical Bayer Schering Pharma Ag
Publication of PL1742926T3 publication Critical patent/PL1742926T3/pl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/0002General or multifunctional contrast agents, e.g. chelated agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/04X-ray contrast preparations
    • A61K49/0433X-ray contrast preparations containing an organic halogenated X-ray contrast-enhancing agent
    • A61K49/0438Organic X-ray contrast-enhancing agent comprising an iodinated group or an iodine atom, e.g. iopamidol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/06Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/085Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier conjugated systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/06Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/10Organic compounds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D257/00Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
    • C07D257/02Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Cosmetics (AREA)
PL05742880T 2004-05-05 2005-04-19 Trimeryczne, makrocyklicznie podstawione pochodne fluorowcobenzenu PL1742926T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE102004023093A DE102004023093B3 (de) 2004-05-05 2004-05-05 Trimere makrocyclisch substituierte Halogen-Benzolderivate
PCT/EP2005/004319 WO2005108379A1 (de) 2004-05-05 2005-04-19 Trimere makrocyclisch substituierte halogen-benzolderivate
EP05742880A EP1742926B1 (de) 2004-05-05 2005-04-19 Trimere makrocyclisch substituierte halogen-benzolderivate

Publications (1)

Publication Number Publication Date
PL1742926T3 true PL1742926T3 (pl) 2007-12-31

Family

ID=34967980

Family Applications (1)

Application Number Title Priority Date Filing Date
PL05742880T PL1742926T3 (pl) 2004-05-05 2005-04-19 Trimeryczne, makrocyklicznie podstawione pochodne fluorowcobenzenu

Country Status (18)

Country Link
US (1) US7385054B2 (pl)
EP (1) EP1742926B1 (pl)
JP (1) JP2007536295A (pl)
AR (1) AR050984A1 (pl)
AT (1) ATE369347T1 (pl)
DE (2) DE102004023093B3 (pl)
DK (1) DK1742926T3 (pl)
ES (1) ES2289711T3 (pl)
GT (1) GT200500106A (pl)
PA (1) PA8632101A1 (pl)
PE (1) PE20060350A1 (pl)
PL (1) PL1742926T3 (pl)
PT (1) PT1742926E (pl)
SI (1) SI1742926T1 (pl)
SV (1) SV2006002104A (pl)
TW (1) TW200539894A (pl)
UY (1) UY28884A1 (pl)
WO (1) WO2005108379A1 (pl)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102007058220A1 (de) 2007-12-03 2009-06-04 Bayer Schering Pharma Aktiengesellschaft Dimere macrocyclisch substituierte Benzolderivate
KR101209633B1 (ko) * 2009-09-09 2012-12-06 주식회사 휴메딕스 페길레이션된 삼요오드화 아릴 화합물 및 그를 포함하는 x-선 조영제
EP3101012A1 (en) 2015-06-04 2016-12-07 Bayer Pharma Aktiengesellschaft New gadolinium chelate compounds for use in magnetic resonance imaging
RU2755181C2 (ru) 2016-11-28 2021-09-14 Байер Фарма Акциенгезельшафт Новые хелатные соединения гадолиния с высокой релаксивностью для применения в магнитно-резонансной визуализации
MX2021006024A (es) 2018-11-23 2021-07-06 Bayer Ag Formulacion de medios de contraste y proceso para prepararlos.

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5324503A (en) * 1992-02-06 1994-06-28 Mallinckrodt Medical, Inc. Iodo-phenylated chelates for x-ray contrast
JPH08510458A (ja) * 1993-06-02 1996-11-05 ブラッコ エッセ.ピ.ア. 沃素化された常磁性キレートおよびそれらの造影剤としての使用法
US7208140B2 (en) 2003-02-19 2007-04-24 Schering Aktiengesellschaft Trimeric macrocyclic substituted benzene derivatives
DE10307759B3 (de) * 2003-02-19 2004-11-18 Schering Ag Trimere makrocyclisch substituierte Benzolderivate, deren Herstellung und Verwendung als Kontrastmittel sowie diese enthaltende pharmazeutische Mittel

Also Published As

Publication number Publication date
PA8632101A1 (es) 2006-07-03
EP1742926A1 (de) 2007-01-17
US20060154989A1 (en) 2006-07-13
DE102004023093B3 (de) 2006-03-02
GT200500106A (es) 2005-12-15
US7385054B2 (en) 2008-06-10
PT1742926E (pt) 2007-09-24
UY28884A1 (es) 2005-11-30
ES2289711T3 (es) 2008-02-01
SI1742926T1 (sl) 2007-12-31
AR050984A1 (es) 2006-12-13
DE502005001194D1 (de) 2007-09-20
TW200539894A (en) 2005-12-16
WO2005108379A1 (de) 2005-11-17
JP2007536295A (ja) 2007-12-13
ATE369347T1 (de) 2007-08-15
PE20060350A1 (es) 2006-05-25
DK1742926T3 (da) 2007-10-15
SV2006002104A (es) 2006-02-15
EP1742926B1 (de) 2007-08-08

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