UY26982A1 - Derivados de indirubina que contienen azufre, su preparación y uso - Google Patents
Derivados de indirubina que contienen azufre, su preparación y usoInfo
- Publication number
- UY26982A1 UY26982A1 UY26982A UY26982A UY26982A1 UY 26982 A1 UY26982 A1 UY 26982A1 UY 26982 A UY26982 A UY 26982A UY 26982 A UY26982 A UY 26982A UY 26982 A1 UY26982 A1 UY 26982A1
- Authority
- UY
- Uruguay
- Prior art keywords
- diseases
- preparation
- disease
- caused
- containing sulfur
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/40—Nitrogen atoms, not forming part of a nitro radical, e.g. isatin semicarbazone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/32—Oxygen atoms
- C07D209/36—Oxygen atoms in position 3, e.g. adrenochrome
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Se describen derivados de sulfanil-indirubina, su preparación y los productos intermedios para su preparación, así como su uso como medicamento para el tratamiento de cánceres tales como tumores sólidos y leucemia, enfermedades autoinmunes como psoriasis, alopecia y esclerosis múltiple, enfermedades cardiovasculares tales como estenosis, arteriosclerosis y restenosis, enfermedades infecciosas como por ejemplo provocadas por parásitos unicelulares, o por hongos, enfermedades nefrológicas, enfermedades neurodegenerativas crónicas, como enfermedad de Huntigton, esclerosis lateral amiotrófica, Parkinson y Alzheimer, enfermedades neurodegenerativas agudas, como isquemias cerebrales y traumas neuronales, infecciones virales, como infecciones de citomegalovirus, herpes, hepatitis B y C, y enfermedades provocadas por HIV.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE10053474A DE10053474A1 (de) | 2000-10-24 | 2000-10-24 | Schwefelhaltige Indirubinderivate, deren Herstellung und Verwendung |
Publications (1)
Publication Number | Publication Date |
---|---|
UY26982A1 true UY26982A1 (es) | 2002-06-20 |
Family
ID=7661370
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
UY26982A UY26982A1 (es) | 2000-10-24 | 2001-10-23 | Derivados de indirubina que contienen azufre, su preparación y uso |
Country Status (6)
Country | Link |
---|---|
US (1) | US20020107404A1 (es) |
AU (1) | AU2002210548A1 (es) |
DE (1) | DE10053474A1 (es) |
PE (1) | PE20030208A1 (es) |
UY (1) | UY26982A1 (es) |
WO (1) | WO2002034717A1 (es) |
Families Citing this family (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6822267B1 (en) * | 1997-08-20 | 2004-11-23 | Advantest Corporation | Signal transmission circuit, CMOS semiconductor device, and circuit board |
DE10114138C2 (de) * | 2001-03-16 | 2003-03-27 | Schering Ag | Cdk-inhibitorische Indirubinderivate mit erhöhter Löslichkeit |
DE10125763A1 (de) * | 2001-05-17 | 2002-11-28 | Schering Ag | Verwendung selektiver Indirubinderivate als VEGF-R Inhibitoren |
US7582670B2 (en) | 2001-12-13 | 2009-09-01 | Natrogen Therapeutics, Inc. | Methods of treating an inflammatory-related disease |
US20050154046A1 (en) * | 2004-01-12 | 2005-07-14 | Longgui Wang | Methods of treating an inflammatory-related disease |
US8563525B2 (en) | 2004-01-12 | 2013-10-22 | Natrogen Therapeutics International, Inc. | Methods of treating an inflammatory-related disease |
US7154002B1 (en) | 2002-10-08 | 2006-12-26 | Takeda San Diego, Inc. | Histone deacetylase inhibitors |
US7250514B1 (en) | 2002-10-21 | 2007-07-31 | Takeda San Diego, Inc. | Histone deacetylase inhibitors |
CA2518318A1 (en) | 2003-03-17 | 2004-09-30 | Takeda San Diego, Inc. | Histone deacetylase inhibitors |
KR100588803B1 (ko) * | 2004-01-27 | 2006-06-12 | 학교법인조선대학교 | 암세포주에 항암활성을 지닌 인디루빈 유도체 |
EP1824831A2 (en) | 2004-12-16 | 2007-08-29 | Takeda San Diego, Inc. | Histone deacetylase inhibitors |
US20080207594A1 (en) | 2005-05-04 | 2008-08-28 | Davelogen Aktiengesellschaft | Use of Gsk-3 Inhibitors for Preventing and Treating Pancreatic Autoimmune Disorders |
JP2008540574A (ja) | 2005-05-11 | 2008-11-20 | タケダ サン ディエゴ インコーポレイテッド | ヒストンデアセチラーゼ阻害剤 |
CA2615105A1 (en) | 2005-07-14 | 2007-01-25 | Takeda San Diego, Inc. | Histone deacetylase inhibitors |
WO2007076372A2 (en) * | 2005-12-23 | 2007-07-05 | University Of Rochester | Treatment of neuroaids using inhibitors of glycogen synthase kinase (gsk)-3 |
AR059066A1 (es) | 2006-01-27 | 2008-03-12 | Amgen Inc | Combinaciones del inhibidor de la angiopoyetina -2 (ang2) y el inhibidor del factor de crecimiento endotelial vascular (vegf) |
CN103391773A (zh) | 2010-09-27 | 2013-11-13 | 埃克塞里艾克西斯公司 | 用于治疗去势抵抗性前列腺癌和成骨性骨转移的met和vegf的双重抑制剂 |
US20150087687A1 (en) | 2012-03-23 | 2015-03-26 | Dennis Brown | Compositions and methods to improve the therapeutic benefit of indirubin and analogs thereof, including meisoindigo |
US9931400B2 (en) | 2012-09-12 | 2018-04-03 | Samsung Electronics Co., Ltd. | Method of combination therapy for prevention or treatment of c-Met or angiogenesis factor induced diseases |
CN103333161B (zh) * | 2013-05-28 | 2015-09-30 | 滁州市洛达生物科技有限公司 | 1’-氧代靛玉红的制备和用途 |
US11083755B2 (en) | 2015-01-08 | 2021-08-10 | The Board Of Trustees Of The Leland Stanford Junior University | Factors and cells that provide for induction of bone, bone marrow, and cartilage |
CN108486186A (zh) * | 2018-03-20 | 2018-09-04 | 合肥皖为生物科技有限公司 | 一种氧化酶制备具有抗肿瘤活性的靛玉红的方法 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2333661A1 (en) * | 1998-05-29 | 1999-12-09 | Cnrs (Centre National De Recherche Scientifique) France Innovation Scien Tifique Et Transfernt | Use of indigoid bisindole derivatives for the manufacture of a medicament to inhibit cyclin dependent kinases |
EP0966963A1 (en) * | 1998-05-29 | 1999-12-29 | Gerhard Prof. Dr. Eisenbrand | Use of indigoid bisindole derivatives as CDK1 inhibitors |
CA2369670A1 (en) * | 1999-04-12 | 2000-10-19 | Gerhard Eisenbrand | Indigoid bisindole derivatives |
-
2000
- 2000-10-24 DE DE10053474A patent/DE10053474A1/de not_active Withdrawn
-
2001
- 2001-10-17 WO PCT/EP2001/012007 patent/WO2002034717A1/de active Search and Examination
- 2001-10-17 AU AU2002210548A patent/AU2002210548A1/en not_active Abandoned
- 2001-10-23 UY UY26982A patent/UY26982A1/es not_active Application Discontinuation
- 2001-10-23 PE PE2001001048A patent/PE20030208A1/es not_active Application Discontinuation
- 2001-10-24 US US09/983,548 patent/US20020107404A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
DE10053474A1 (de) | 2002-05-02 |
US20020107404A1 (en) | 2002-08-08 |
WO2002034717A1 (de) | 2002-05-02 |
PE20030208A1 (es) | 2003-04-03 |
AU2002210548A1 (en) | 2002-05-06 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
UY26982A1 (es) | Derivados de indirubina que contienen azufre, su preparación y uso | |
USD988218S1 (en) | Vehicle instrument panel | |
USD908070S1 (en) | Wheel | |
USD895513S1 (en) | Wheel | |
USD904957S1 (en) | Wheel | |
PT1387840E (pt) | 3,5-diamino-1,2,4-triazoles como inibidoras cinases | |
BR0017030A (pt) | Derivados de tiazolilamida | |
USD901592S1 (en) | Vehicle-mounted sign | |
USD922295S1 (en) | Wheel | |
USD924973S1 (en) | Vehicle-mounted sign | |
BR0307819A (pt) | Derivados de pirazol tricìclicos, processo para preparação dos mesmos como agentes antitumorais | |
ES2099758T3 (es) | Procedimiento para preparar catalizadores para polimerizacion por adicion mediante oxidacion del nucleo metalico. | |
USD865618S1 (en) | Wheel | |
USD924971S1 (en) | Vehicle-mounted sign | |
USD927737S1 (en) | Auxiliary vehicle light | |
WO2002074742A3 (de) | Cdk-inhibitorische indirubinderivate mit erhöhter löslichkeit | |
SV1998000023A (es) | Arilsulfonamidas y analogos ref. lea 32316-sv | |
ATE151776T1 (de) | Cytotoxische und antivirale verbindung | |
UY27293A1 (es) | Uso de derivados selectivos de indirrubina como inhibidores de vegr-r | |
WO2004043402A3 (en) | Modified nucleosides as antiviral agents | |
UY27043A1 (es) | Derivados de indirubina aril-sustituidos, su preparación y uso | |
IT7825578A0 (it) | Processo per la produzione di nuovi cromone-derivati nonche' loro impiego come materiali protettivi delle piante. | |
IT1078784B (it) | Processo per la produzione di triazin 2.4 dioni nonche loro impiego come insetticidi | |
TH62087EX (th) | พวงมาลัย | |
ITTV950007A1 (it) | Struttura di casco protettivo, particolarmente per il ciclismo |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
109 | Application deemed to be withdrawn |
Effective date: 20150126 |