US3918909A - Apparatus for performing saturation analyses - Google Patents

Apparatus for performing saturation analyses Download PDF

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Publication number
US3918909A
US3918909A US290650A US29065072A US3918909A US 3918909 A US3918909 A US 3918909A US 290650 A US290650 A US 290650A US 29065072 A US29065072 A US 29065072A US 3918909 A US3918909 A US 3918909A
Authority
US
United States
Prior art keywords
separating agent
reaction compartment
tubular member
radioactive
compartment
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
US290650A
Other languages
English (en)
Inventor
Jan Jacob Arlman
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
MAALLINCKRODT DIAGNOSTICA (HOLLAND) BV WESTERDUINWEG 3 1755 LE PETTEN NETHERLANDS
US Philips Corp
Original Assignee
US Philips Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by US Philips Corp filed Critical US Philips Corp
Application granted granted Critical
Publication of US3918909A publication Critical patent/US3918909A/en
Assigned to MAALLINCKRODT DIAGNOSTICA (HOLLAND) B.V., WESTERDUINWEG 3, 1755 LE PETTEN, THE NETHERLANDS reassignment MAALLINCKRODT DIAGNOSTICA (HOLLAND) B.V., WESTERDUINWEG 3, 1755 LE PETTEN, THE NETHERLANDS CHANGE OF NAME (SEE DOCUMENT FOR DETAILS). EFFECTIVE DATE: SEPTEMBER 3, 1984 Assignors: BYK-MALLINCKRODT CIL B.V.
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S220/00—Receptacles
    • Y10S220/916—Container including axially opposed removable closures
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/804—Radioisotope, e.g. radioimmunoassay
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/807—Apparatus included in process claim, e.g. physical support structures
    • Y10S436/81—Tube, bottle, or dipstick

Definitions

  • the instrument 215/6 comprises a reaction compartment and a separating (51] Int. Cl.' GOIN 31/06: B0lL 3/00 compartment separated from the reaction compart- [58] Field of Search 23/230 R. 253 R. 230 B. ment.
  • the reaction compartment is provided with a 23/259. 292, 258.5; 206/47 A; 2 lS/f); 128/272 wall portion which may be rendered permeable to liquid thereby enabling the contents of the reaction [56] References Cited compartment to flow to the separating compartment.
  • the upper and lower parts of the tubular member are joined to one another by an intermediate part which is provided with a central bore in which a slide is mounted which is displaceable in a direction at right angles to the axis of the bore so as to completely close the bore in one extreme position and to completely open the bore in the other extreme position.
  • a device suitable for performing a saturation analysis in which by the use of a separating agent a radioactive-substance bound to a competitive binder is separated from its unbound form which device comprises a tubular member open at both ends and containing in a lower part the separating agent and containing in an upper part a reaction compartment containing a radioactive reagent, said reaction compartment being a container closed with respect to the separating agent and having a non-porous bottom portion facing the separating agent which may be rendered permeable to liquid and said non-porous bottom portion including a hydrophobic porous filter capable of being made permeable to liquid by shaking or by providing a pressure differential between the reaction compartment and the remainder of the tubular member.

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
US290650A 1971-09-21 1972-09-20 Apparatus for performing saturation analyses Expired - Lifetime US3918909A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
NL7112927A NL7112927A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1971-09-21 1971-09-21

Publications (1)

Publication Number Publication Date
US3918909A true US3918909A (en) 1975-11-11

Family

ID=19814063

Family Applications (1)

Application Number Title Priority Date Filing Date
US290650A Expired - Lifetime US3918909A (en) 1971-09-21 1972-09-20 Apparatus for performing saturation analyses

Country Status (12)

Country Link
US (1) US3918909A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
JP (1) JPS4841793A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AU (1) AU4686072A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
BE (1) BE789059A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CA (1) CA978456A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CH (1) CH582883A5 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DE (1) DE2245797A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
FR (1) FR2154175A5 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
GB (1) GB1383989A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IT (1) IT965403B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NL (1) NL7112927A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ZA (1) ZA726367B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2912173A1 (de) * 1978-03-31 1979-10-04 Union Carbide Corp Reaktor/separator-vorrichtung
US4225575A (en) * 1978-05-15 1980-09-30 Ventrex Laboratories, Inc. Method and apparatus for performing in vitro clinical diagnostic tests using a solid phase assay system
US4442218A (en) * 1981-05-27 1984-04-10 Corning Glass Works Method of measuring degree of partitioning
US4871683A (en) * 1985-04-18 1989-10-03 Beckman Instruments, Inc. Apparatus and method using a new reaction capsule
US4939153A (en) * 1989-01-25 1990-07-03 Radian Corporation Saturation monitor and process
WO1990008950A1 (en) * 1989-01-25 1990-08-09 Radian Corporation Saturation monitor and process
US6001643A (en) * 1997-08-04 1999-12-14 C-Med Inc. Controlled hydrodynamic cell culture environment for three dimensional tissue growth
US20020057996A1 (en) * 2000-04-10 2002-05-16 Bass Leland L. Centrifuge tube assembly
US6401552B1 (en) * 2000-04-17 2002-06-11 Carlos D. Elkins Centrifuge tube and method for collecting and dispensing mixed concentrated fluid samples
US20020156439A1 (en) * 1997-09-12 2002-10-24 Michael J. Iskra Collection container assembly

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3932222A (en) * 1974-12-20 1976-01-13 J. K. & Susie L. Wadley Research Institute And Blood Bank For isolating pathogenic microorganisms
DE2923529A1 (de) * 1979-06-09 1980-12-11 Abimed Analysen Technik Gmbh Filtrier- und zentrifugenbecher
GB8311730D0 (en) * 1983-04-29 1983-06-02 Bagshawe K D Handling of reaction mixtures
EP0254794A1 (fr) * 1986-07-31 1988-02-03 Laboratoires Sanders-Probel, S.A. Colonne de réaction
US5006309A (en) * 1988-04-22 1991-04-09 Abbott Laboratories Immunoassay device with liquid transfer between wells by washing
US5198368A (en) * 1988-04-22 1993-03-30 Abbott Laboratories Methods for performing a solid-phase immunoassay
US5089424A (en) * 1988-06-14 1992-02-18 Abbott Laboratories Method and apparatus for heterogeneous chemiluminescence assay
US5525475A (en) * 1992-08-12 1996-06-11 Ladouceur; Cynthia A. Diffusion through a membrane assaying apparatus and method

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1706334A (en) * 1927-06-03 1929-03-19 Standard Varnish Works Receptacle for paints, etc.
US1765794A (en) * 1927-03-11 1930-06-24 Hirth Albert Tubular container for viscous materials
US2612163A (en) * 1950-10-09 1952-09-30 Wilson Y Norman Container for hypodermic preparations
US3380888A (en) * 1961-03-31 1968-04-30 Squibb & Sons Inc Test units
US3659104A (en) * 1970-06-29 1972-04-25 Univ Jerusalem The Method of measuring serum thyroxine
US3707353A (en) * 1970-03-26 1972-12-26 Minnesota Mining & Mfg Radioactive labeling kit

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1765794A (en) * 1927-03-11 1930-06-24 Hirth Albert Tubular container for viscous materials
US1706334A (en) * 1927-06-03 1929-03-19 Standard Varnish Works Receptacle for paints, etc.
US2612163A (en) * 1950-10-09 1952-09-30 Wilson Y Norman Container for hypodermic preparations
US3380888A (en) * 1961-03-31 1968-04-30 Squibb & Sons Inc Test units
US3707353A (en) * 1970-03-26 1972-12-26 Minnesota Mining & Mfg Radioactive labeling kit
US3659104A (en) * 1970-06-29 1972-04-25 Univ Jerusalem The Method of measuring serum thyroxine

Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2912173A1 (de) * 1978-03-31 1979-10-04 Union Carbide Corp Reaktor/separator-vorrichtung
US4244694A (en) * 1978-03-31 1981-01-13 Union Carbide Corporation Reactor/separator device for use in automated solid phase immunoassay
US4225575A (en) * 1978-05-15 1980-09-30 Ventrex Laboratories, Inc. Method and apparatus for performing in vitro clinical diagnostic tests using a solid phase assay system
US4442218A (en) * 1981-05-27 1984-04-10 Corning Glass Works Method of measuring degree of partitioning
US4871683A (en) * 1985-04-18 1989-10-03 Beckman Instruments, Inc. Apparatus and method using a new reaction capsule
US4939153A (en) * 1989-01-25 1990-07-03 Radian Corporation Saturation monitor and process
WO1990008950A1 (en) * 1989-01-25 1990-08-09 Radian Corporation Saturation monitor and process
US6001643A (en) * 1997-08-04 1999-12-14 C-Med Inc. Controlled hydrodynamic cell culture environment for three dimensional tissue growth
US20020156439A1 (en) * 1997-09-12 2002-10-24 Michael J. Iskra Collection container assembly
US20020057996A1 (en) * 2000-04-10 2002-05-16 Bass Leland L. Centrifuge tube assembly
US6401552B1 (en) * 2000-04-17 2002-06-11 Carlos D. Elkins Centrifuge tube and method for collecting and dispensing mixed concentrated fluid samples

Also Published As

Publication number Publication date
AU4686072A (en) 1974-03-28
NL7112927A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1973-03-23
GB1383989A (en) 1974-02-12
CH582883A5 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1976-12-15
DE2245797A1 (de) 1973-03-29
JPS4841793A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1973-06-18
CA978456A (en) 1975-11-25
IT965403B (it) 1974-01-31
BE789059A (fr) 1973-03-20
FR2154175A5 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1973-05-04
ZA726367B (en) 1974-04-24

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Legal Events

Date Code Title Description
AS Assignment

Owner name: MAALLINCKRODT DIAGNOSTICA (HOLLAND) B.V., WESTERDU

Free format text: CHANGE OF NAME;ASSIGNOR:BYK-MALLINCKRODT CIL B.V.;REEL/FRAME:004466/0151

Effective date: 19850728