US3847200A - Apparatus for concentrating laboratory specimens by evaporation - Google Patents
Apparatus for concentrating laboratory specimens by evaporation Download PDFInfo
- Publication number
- US3847200A US3847200A US00248820A US24882072A US3847200A US 3847200 A US3847200 A US 3847200A US 00248820 A US00248820 A US 00248820A US 24882072 A US24882072 A US 24882072A US 3847200 A US3847200 A US 3847200A
- Authority
- US
- United States
- Prior art keywords
- chambers
- vessels
- air
- base
- cover assembly
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Images
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/508—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
- B01L3/5085—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above for multiple samples, e.g. microtitration plates
- B01L3/50851—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above for multiple samples, e.g. microtitration plates specially adapted for heating or cooling samples
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/508—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
- B01L3/5085—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above for multiple samples, e.g. microtitration plates
- B01L3/50853—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above for multiple samples, e.g. microtitration plates with covers or lids
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/40—Concentrating samples
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/40—Concentrating samples
- G01N1/4022—Concentrating samples by thermal techniques; Phase changes
- G01N2001/4027—Concentrating samples by thermal techniques; Phase changes evaporation leaving a concentrated sample
Definitions
- the specimen con- 217T684 7/1879 Elmerw: tainers are heated from a controlled source, such as a 20 7 2 3/1378 E m thermostatically controlled heat sink. 937,l 14 10/1909 Suzuki 3,084,537 4/1963 Shipstead 159 16 3 3 D'awmg 1 2 APPARATUS FOR CONCENTRATING DESCRIPTION OF THE PREFERRED LABORATORY SPECIMENS BY EVAPORATION EMBODIMENT BACKGROUND OF THE INVENTION
- Th h evaporatable medium mg mbly as best seen In FIG. 2, includes a ba ⁇ mu-m u
- laboratory specimens are COIIC'fl- 1' foffi more volatllfi liquids or H 12mmlgmumhwmSmmmm ⁇ m% 0 a l I i m 2x3115322 L ml will if lffilfil'fil I 10 ex aust to h 1S sphere m order to prevent the accumulation f t hiatus l5 and led by titer. m the laboratory.
- the cover assembly 24' includes nozzle tubes 33 (which can correspond in num-. bet to the number of rows of specimen vials) supported by the end walls of the cover assembly 24.
- the nozzle tubes 33 are vented at their ends to the atmosphere and include at equally spaced points along their lengths radial bores 34-l, 34-2 34-36 directed downwardly to the respective" specimen holders.
- the entire inside chamber 35 of the cover assembly defines the exhaust manifold and the spaces within the nozzle tubes 33 define the intake manifold. With the chamber 35 placed under sub-atmospheric pressure, the system functions identically with that described above having reference to FIG. 2.
- Apparatus for concentrating laboratory specimens byevaporation comprising a base receptacle for a plurality of specimen vessels and including a heat sink having a plurality of individual chambers adapted to have seated therein open vessels containing laboratory specimens, a heat source for the-heat sink including means to regulate the temperature thereof, a detachable cover assembly adapted to be seated in substantially air-tight relationship on the base over the chambers, said cover assembly comprising depending side walls including opposing end portions to engage the base in air-tight relationship, at least one rigid horizontal tube member carried by and joined to the opposing side walls and open to the atmosphere through at least one sidewall, the tube member passing horizontally over a plurality of said chambers in close proximity thereto and carrying a plurality of downwardly directed air orifices aligned respectively with the plurality of chambers below, and means to establish sub-atmospheric pressure in the closed, space whereby air is drawn into the tube member and discharged downwardly in a plurality of jet streams into the
Abstract
Description
Claims (3)
Priority Applications (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US00248820A US3847200A (en) | 1972-05-01 | 1972-05-01 | Apparatus for concentrating laboratory specimens by evaporation |
GB635473A GB1427034A (en) | 1972-05-01 | 1973-02-08 | Apparatus for concentrating laboratory specimens by evaporation |
DE19732307274 DE2307274A1 (en) | 1972-05-01 | 1973-02-14 | DEVICE FOR THE CONCENTRATION OF LABORATORY SAMPLES BY EVAPORATION |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US00248820A US3847200A (en) | 1972-05-01 | 1972-05-01 | Apparatus for concentrating laboratory specimens by evaporation |
Publications (1)
Publication Number | Publication Date |
---|---|
US3847200A true US3847200A (en) | 1974-11-12 |
Family
ID=22940826
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US00248820A Expired - Lifetime US3847200A (en) | 1972-05-01 | 1972-05-01 | Apparatus for concentrating laboratory specimens by evaporation |
Country Status (3)
Country | Link |
---|---|
US (1) | US3847200A (en) |
DE (1) | DE2307274A1 (en) |
GB (1) | GB1427034A (en) |
Cited By (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4465554A (en) * | 1982-02-25 | 1984-08-14 | Mobil Oil Corporation | Hot jet evaporator |
EP0178793A2 (en) * | 1984-10-18 | 1986-04-23 | Analytical Bio-Chemistry Laboratories, Inc. | Automatic evaporator system |
EP0259307A1 (en) * | 1984-11-09 | 1988-03-16 | Zymark Corp | Control of laboratory evaporation. |
EP0425216A2 (en) * | 1989-10-23 | 1991-05-02 | Zymark Corporation | Laboratory evaporation apparatus |
EP0488769A2 (en) * | 1990-11-29 | 1992-06-03 | The Perkin-Elmer Corporation | Thermal cycler for automatic performance of the polymerase chain reaction with close temperature control |
EP0711603A1 (en) * | 1994-11-11 | 1996-05-15 | Roche Diagnostics GmbH | System for incubating sample fluids |
US5585068A (en) * | 1990-02-20 | 1996-12-17 | Biochemical Diagnostics, Inc. | Apparatus for automatically separating a compound from a plurality of discrete liquid specimens |
EP0776967A3 (en) * | 1986-02-25 | 1997-09-10 | Perkin Elmer Corp | Heat exchanger for use in a temperature cycling instrument |
EP1027933A1 (en) * | 1999-02-10 | 2000-08-16 | Büchi Labortechnik AG | Device and method for sample treatment |
US6132684A (en) * | 1997-10-31 | 2000-10-17 | Becton Dickinson And Company | Sample tube holder |
EP1174703A2 (en) * | 2000-07-18 | 2002-01-23 | Volker Barkey | Evaporator for samples |
WO2003008953A2 (en) * | 2001-07-17 | 2003-01-30 | E.I. Du Pont De Nemours And Company | Sublimation screening test and apparatus |
US20030108450A1 (en) * | 2000-05-11 | 2003-06-12 | Irm Llc | Specimen plate lid and method of using |
US20040151638A1 (en) * | 2002-07-17 | 2004-08-05 | Lecloux Daniel David | Sublimation screening test and apparatus |
US20050158211A1 (en) * | 2004-01-16 | 2005-07-21 | Piacenza Donna A. | Pipette device with pivotable nozzle assembly |
US20060242857A1 (en) * | 2005-04-11 | 2006-11-02 | Eppendorf Ag | Apparatus, a system incorporating such apparatus, and a method to dry microtitration filter tray cavities and received filters therein |
US20090010809A1 (en) * | 2007-07-03 | 2009-01-08 | Hadjis Peter T | Manual pipette filler |
US20090007701A1 (en) * | 2007-07-03 | 2009-01-08 | Hadjis Peter T | Pivoting pipette device |
USD802158S1 (en) * | 2014-05-23 | 2017-11-07 | John Bethune | Ampoule stand |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2644356B1 (en) * | 1989-03-20 | 1992-11-20 | Jouan | PROCESS OF CONCENTRATION OF SAMPLES BY EVAPORATION OF THE SOLVENT AND CENTRIFUGAL EVAPORATOR-CONCENTRATOR FOR THE IMPLEMENTATION OF THIS PROCESS |
ATE237399T1 (en) | 1999-09-29 | 2003-05-15 | Tecan Trading Ag | THERMOCYCLER AND LIFTING ELEMENT FOR MICROTITER PLATE |
US7169355B1 (en) | 2000-02-02 | 2007-01-30 | Applera Corporation | Apparatus and method for ejecting sample well trays |
WO2009030342A1 (en) * | 2007-08-28 | 2009-03-12 | Arzneimittel Gmbh Apotheker Vetter & Co. Ravensburg | Receptacle |
ES2877137T3 (en) * | 2016-02-18 | 2021-11-16 | Siemens Healthcare Diagnostics Inc | Frame for a filtration device |
EP3933375B1 (en) * | 2020-06-30 | 2024-02-28 | F. Hoffmann-La Roche AG | Automatic sample concentrating unit |
Citations (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5570A (en) * | 1848-05-16 | Nathan towson | ||
US42398A (en) * | 1864-04-19 | Improvement in apparatus for concentrating milk | ||
US201762A (en) * | 1878-03-26 | Improvement in apparatus for the manufacture of salt | ||
US217684A (en) * | 1879-07-22 | Improvement in processes and apparatus for the manufacture of salt | ||
US937114A (en) * | 1908-10-03 | 1909-10-19 | Tozaburo Suzuki | Evaporator. |
US2385962A (en) * | 1941-08-23 | 1945-10-02 | Foundry Equipment Company | Method of and apparatus for conditioning molds and the like |
CA451686A (en) * | 1948-10-05 | Nathaniel Hoyler Cyril | Art of concentrating drugs, etc. | |
US2660513A (en) * | 1949-06-30 | 1953-11-24 | Ball Charles Olin | Method of sterilizing glass containers |
US2771645A (en) * | 1950-12-04 | 1956-11-27 | Dole Eng Co James | Apparatus for sterilizing food containers |
US2803888A (en) * | 1954-04-27 | 1957-08-27 | Cerletti Santiago | Apparatus for lyophilising products contained in small bottles |
US3084537A (en) * | 1958-04-30 | 1963-04-09 | Shipstead Helge | Method and apparatus for determining total solids in organic liquid materials |
US3565767A (en) * | 1965-03-11 | 1971-02-23 | Polycom Corp | Method and apparatus for removing dissolved impurities from water |
-
1972
- 1972-05-01 US US00248820A patent/US3847200A/en not_active Expired - Lifetime
-
1973
- 1973-02-08 GB GB635473A patent/GB1427034A/en not_active Expired
- 1973-02-14 DE DE19732307274 patent/DE2307274A1/en active Pending
Patent Citations (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5570A (en) * | 1848-05-16 | Nathan towson | ||
US42398A (en) * | 1864-04-19 | Improvement in apparatus for concentrating milk | ||
US201762A (en) * | 1878-03-26 | Improvement in apparatus for the manufacture of salt | ||
US217684A (en) * | 1879-07-22 | Improvement in processes and apparatus for the manufacture of salt | ||
CA451686A (en) * | 1948-10-05 | Nathaniel Hoyler Cyril | Art of concentrating drugs, etc. | |
US937114A (en) * | 1908-10-03 | 1909-10-19 | Tozaburo Suzuki | Evaporator. |
US2385962A (en) * | 1941-08-23 | 1945-10-02 | Foundry Equipment Company | Method of and apparatus for conditioning molds and the like |
US2660513A (en) * | 1949-06-30 | 1953-11-24 | Ball Charles Olin | Method of sterilizing glass containers |
US2771645A (en) * | 1950-12-04 | 1956-11-27 | Dole Eng Co James | Apparatus for sterilizing food containers |
US2803888A (en) * | 1954-04-27 | 1957-08-27 | Cerletti Santiago | Apparatus for lyophilising products contained in small bottles |
US3084537A (en) * | 1958-04-30 | 1963-04-09 | Shipstead Helge | Method and apparatus for determining total solids in organic liquid materials |
US3565767A (en) * | 1965-03-11 | 1971-02-23 | Polycom Corp | Method and apparatus for removing dissolved impurities from water |
Cited By (35)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4465554A (en) * | 1982-02-25 | 1984-08-14 | Mobil Oil Corporation | Hot jet evaporator |
EP0178793A2 (en) * | 1984-10-18 | 1986-04-23 | Analytical Bio-Chemistry Laboratories, Inc. | Automatic evaporator system |
EP0178793A3 (en) * | 1984-10-18 | 1987-12-16 | Analytical Bio-Chem Lab | Automatic evaporator system |
EP0259307A1 (en) * | 1984-11-09 | 1988-03-16 | Zymark Corp | Control of laboratory evaporation. |
EP0259307A4 (en) * | 1984-11-09 | 1988-11-22 | Zymark Corp | Control of laboratory evaporation. |
EP0776967A3 (en) * | 1986-02-25 | 1997-09-10 | Perkin Elmer Corp | Heat exchanger for use in a temperature cycling instrument |
EP0425216A2 (en) * | 1989-10-23 | 1991-05-02 | Zymark Corporation | Laboratory evaporation apparatus |
EP0425216A3 (en) * | 1989-10-23 | 1992-03-25 | Zymark Corporation | Laboratory evaporation apparatus |
US5585068A (en) * | 1990-02-20 | 1996-12-17 | Biochemical Diagnostics, Inc. | Apparatus for automatically separating a compound from a plurality of discrete liquid specimens |
US6015534A (en) * | 1990-11-29 | 2000-01-18 | The Perkin-Elmer Corporation | PCR sample tube |
EP0488769A2 (en) * | 1990-11-29 | 1992-06-03 | The Perkin-Elmer Corporation | Thermal cycler for automatic performance of the polymerase chain reaction with close temperature control |
US5475610A (en) * | 1990-11-29 | 1995-12-12 | The Perkin-Elmer Corporation | Thermal cycler for automatic performance of the polymerase chain reaction with close temperature control |
US5602756A (en) * | 1990-11-29 | 1997-02-11 | The Perkin-Elmer Corporation | Thermal cycler for automatic performance of the polymerase chain reaction with close temperature control |
EP0488769A3 (en) * | 1990-11-29 | 1993-05-26 | Perkin-Elmer Cetus Instruments | Thermal cycler for automatic performance of the polymerase chain reaction with close temperature control |
US5710381A (en) * | 1990-11-29 | 1998-01-20 | The Perkin-Elmer Corporation | Two piece holder for PCR sample tubes |
US5670120A (en) * | 1994-11-11 | 1997-09-23 | Boehringer Mannheim Gmbh | System for incubating sample liquids |
EP0711603A1 (en) * | 1994-11-11 | 1996-05-15 | Roche Diagnostics GmbH | System for incubating sample fluids |
US6132684A (en) * | 1997-10-31 | 2000-10-17 | Becton Dickinson And Company | Sample tube holder |
EP1027933A1 (en) * | 1999-02-10 | 2000-08-16 | Büchi Labortechnik AG | Device and method for sample treatment |
WO2000047324A1 (en) * | 1999-02-10 | 2000-08-17 | Büchi Labortechnik AG | Device and method for processing samples |
US20030108450A1 (en) * | 2000-05-11 | 2003-06-12 | Irm Llc | Specimen plate lid and method of using |
EP1174703A3 (en) * | 2000-07-18 | 2003-04-16 | Volker Barkey | Evaporator for samples |
EP1174703A2 (en) * | 2000-07-18 | 2002-01-23 | Volker Barkey | Evaporator for samples |
US20030054565A1 (en) * | 2001-07-17 | 2003-03-20 | Lecloux Daniel David | Sublimation screening test and apparatus |
WO2003008953A2 (en) * | 2001-07-17 | 2003-01-30 | E.I. Du Pont De Nemours And Company | Sublimation screening test and apparatus |
WO2003008953A3 (en) * | 2001-07-17 | 2003-10-30 | Du Pont | Sublimation screening test and apparatus |
US7179656B2 (en) | 2001-07-17 | 2007-02-20 | E. I. Du Pont De Nemours And Company | Sublimation screening test and apparatus |
US20040151638A1 (en) * | 2002-07-17 | 2004-08-05 | Lecloux Daniel David | Sublimation screening test and apparatus |
US20050158211A1 (en) * | 2004-01-16 | 2005-07-21 | Piacenza Donna A. | Pipette device with pivotable nozzle assembly |
US7381371B2 (en) | 2004-01-16 | 2008-06-03 | Heathrow Scientific Llc | Pipette device with pivotable nozzle assembly |
US20060242857A1 (en) * | 2005-04-11 | 2006-11-02 | Eppendorf Ag | Apparatus, a system incorporating such apparatus, and a method to dry microtitration filter tray cavities and received filters therein |
US7858393B2 (en) * | 2005-04-11 | 2010-12-28 | Eppendorf Ag | Method to dry microtitration filter tray cavities and received filters therein |
US20090010809A1 (en) * | 2007-07-03 | 2009-01-08 | Hadjis Peter T | Manual pipette filler |
US20090007701A1 (en) * | 2007-07-03 | 2009-01-08 | Hadjis Peter T | Pivoting pipette device |
USD802158S1 (en) * | 2014-05-23 | 2017-11-07 | John Bethune | Ampoule stand |
Also Published As
Publication number | Publication date |
---|---|
GB1427034A (en) | 1976-03-03 |
DE2307274A1 (en) | 1973-11-22 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
AS | Assignment |
Owner name: SYBRON CORPORATION, ROCHESTER, NY., A CORP. OF NY Free format text: ASSIGNMENT OF ASSIGNORS INTEREST.;ASSIGNOR:BRINKMANN INSTRUMENTS, INC., (NOW BY CHANGE OF NAME) CANTIAQUE CAPITAL CORPORATION, A CORP. OF NY.;REEL/FRAME:003857/0566 Effective date: 19810427 |
|
AS | Assignment |
Owner name: BRINKMANN INSTRUMENTS INC., CANTIAGUE ROAD, WESTBU Free format text: ASSIGNMENT OF ASSIGNORS INTEREST.;ASSIGNOR:SYBRON TRANSITION CORP., A CORP OF DE.;REEL/FRAME:004671/0136 Effective date: 19870204 Owner name: BRINKMANN INSTRUMENTS INC., A CORP OF DE.,NEW YORK Free format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNOR:SYBRON TRANSITION CORP., A CORP OF DE.;REEL/FRAME:004671/0136 Effective date: 19870204 |