US3794453A - Capsule making apparatus - Google Patents

Capsule making apparatus Download PDF

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Publication number
US3794453A
US3794453A US00277396A US3794453DA US3794453A US 3794453 A US3794453 A US 3794453A US 00277396 A US00277396 A US 00277396A US 3794453D A US3794453D A US 3794453DA US 3794453 A US3794453 A US 3794453A
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United States
Prior art keywords
pin
pins
loading station
bars
air
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
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US00277396A
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English (en)
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S Padilla
R Curtis
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Individual
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Individual
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A61J3/07Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use
    • A61J3/071Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use into the form of telescopically engaged two-piece capsules
    • A61J3/077Manufacturing capsule shells
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B29WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29CSHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C41/00Shaping by coating a mould, core or other substrate, i.e. by depositing material and stripping-off the shaped article; Apparatus therefor
    • B29C41/02Shaping by coating a mould, core or other substrate, i.e. by depositing material and stripping-off the shaped article; Apparatus therefor for making articles of definite length, i.e. discrete articles
    • B29C41/14Dipping a core

Definitions

  • ABSTRACT [52] US. [51] Int Cl [58] Field of Search425/269, 270, 385, 324, 324 B;
  • This invention relates to capsule making apparatus and more particularly to an improvement in means for .movement through drying kilns until the film has solidified. It has been considered essential in this operation to rotate the pin bars during elevation in order to maintain uniform distribution of the liquid film on the pins. Nevertheless, the practice often results in a nonuniform thickness in the capsule shell wall, particularly in the so-called shoulder area. It is found, for example, that the shoulder wall on the leading side of the pin in the direction of the rotation is usually thin whereas on the trailing side it is relatively thick.
  • FIG. I is an elevational view partly in section of capsule making apparatus including a dipping tank, elevator and air duct system;
  • FIG. 2 is a view of the air duct of FIG. 1;
  • FIG. 3 is a fragmented view of an air duct
  • FIGS. 4 and 5 are enlarged views of coated mold pins in the pin down and pin up positions, respectively.
  • the dipping tank which may be conventional in form includes a dipping dish 11 surrounded by a reservoir 12 containing dipping solution 13 in a constant temperature jacket 14.
  • Capsule pins mounted on bars 21 are located, as illustrated, at successive work stations of the operation: at the dipping station A, at the base or loading station B of an elevator 30, at the unloading station C (dotted outline), and at a platform which is the starting run D through a series of driers.
  • Mechanical finger means (not shown) are provided in connection with'each dipping cycle for engaging and sliding the pin bar set at A along a guide track 22 into the loading station B of the elevator.
  • the elevator has a pair of vertical racks 31 which cooperate with a like pair of pinion gears 32 and discs 33.
  • the two discs each have a groove 34 and are spaced in the loading position illustrated, with the grooves in alignment with the top surface of the guide track 22, to receive the opposite ends of each advancing pin bar for loading.
  • a flanged retainer ring 35 Surrounding the elevator disc 33 is a flanged retainer ring 35 which remains stationary with respect to the disc and thus serves to retain the pin bars within the groove as the disc rotates while moving upwardly on the rack.
  • the gear and rack combination is arranged for movement of the elevator to the upper terminal position C illustrated in dotted outline at which the elevated pin bars stand in the pin up position for transfer from the groove 34 to the platform 40.
  • an air duct or conduit is provided having an open outlet 51 located below the loading position B.
  • the air duct communicates with a suitable source (not shown) of clean air under positive pressure at room temperature or lower temperature.
  • a suitable source not shown
  • the air duct outlet 51 is sufficiently large to surround the array of pin ends 20a of bars at the loading station.
  • the end of the conduit 50 may have an outward flare 52 to favor a greater outward flow of air around the perimeter of the array of pins.
  • FIG. 2 features distribution baffles 53 and a screen tray 54 which insure uniform air flow across the opening 51 through the confined zone surrounding the pin ends 20a at the loading station.
  • the screen tray preferably fits the outlet opening closely and is removable for cleaning purposes.
  • Opening 51b serves to provide clearance for unloading the bars 21 from station C to the platform 40.
  • the pins 20 are dipped in gel solution, withdrawn, exposed to air flow and transferred to the loading station B, elevated with rotation, transferred to the drier, dried, stripped, and greased (in preparation for the next cycle).
  • the solution which may be an aqueous gelatin solution is maintained at a suitable temperature, conveniently in the range'from about ll0-l15 F.
  • the pins are dipped five bars at a time at the rate 0E0 bars per minute. The time required for dipping, loading, and elevation and transfer to the drying platform 40 is about 15 seconds. Transfer to the elevator (position A to position B) requires less than one second, following which the pin bar sets come to a dead stop.
  • air is delivered through the orifice 51 (or 51a, FIG. 3) under conditions such as to cool and stabilize the film coating on the pins, for example at room temperature or lower under controlled humidity, preferably 50 percent or lower, and at a linear flow rate of about 5 feet per second.
  • the air-flow conveniently is continuous so that the pins are exposed to the same during the transfer to position B and during the dead stop and elevation. Substantially all of the filmstabilizing effect takes place during the transfer and dead stop.
  • the elevator is activated in conventional manner and the loaded pin bar sets are rotated to the terminal position C adjacent the drier platform 40.
  • the pins While being elevated the pins are rotated (standard rotation is two and one-half times) from the pin down position tothe'pin up position illustrated in dotted outline. Following a short dwell time, the pin sets are transferred to the drier platform 40 and are then processed through the remainder of the cycle in conventional fashion.
  • FIG. 4 illustrates the deformation of the film coating 22a shown in dotted outline as the pin 20 is being rotated from the load position and elevated.
  • the film coating 22b shown in solid outline is typical of the air treated coating during the same phase of rotation.
  • the film coating at the shoulder line 20b remains substantially uniform.
  • FIG. 5 illustrates the configuration of the coating of the fully elevated pin.
  • the dotted outline 22b illustrates the coating profile as the pin first arrives at position C.
  • the solid outline 22c illustrates the profile of the finished film dried on the pin.
  • the film coating at the end 20a of the pin is relatively thick. However, with progressive drying the coating evenly redistributes itself axially upon the surface of the pin to provide a generally uniform thickness.
  • a critical measure of quality of molded capsules concerns the variation in wall thickness at the shoulder line 20b.
  • the wall thickness in a given capsule should be constant throughout the shoulder line.
  • the wall should be relatively thick at the shoulder.
  • capsule making apparatus comprising a set of capsule pin bars having elongated pins each pin having a rounded end, a dipping tank, and means for transferring the pin bars continuously in timed relation through a stepwise cycle of pin dipping in gel solution, withdrawing and inverting the pins while coated with liquid film which is subject to uneven distribution during transfer under action of gravity, and drying and stripping the coating on the pins
  • the transfer means including an elevator for lifting and rotating pin bars from a loading station and means for supplying the loading station with bars of freshly dipped pins with the rounde end of each pin lowermost
  • air conduit means having a distribution orifice located adjacent the loading station for moving cooling air upwardly against the rounded ends of the coated pins, the orifice being shaped to provide for uniform flow through a confined zone surrounding the array-of pin ends of bars at the loading station.
  • Apparatus according to claim 1 wherein the distribution orifice is located above the loading station and the air conduit means is in communication with a source of negative air pressure.
  • Apparatus according to claim 1 wherein the air conduit means is in communication with a source of air pressure adapted to generate air flow through the confined zone at a rate sufficient to stabilize the liquid film coating on coated pins located at the loading station.

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Manufacturing & Machinery (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Mechanical Engineering (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Formation And Processing Of Food Products (AREA)
  • Medicinal Preparation (AREA)
  • Drying Of Solid Materials (AREA)
US00277396A 1972-08-02 1972-08-02 Capsule making apparatus Expired - Lifetime US3794453A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US27739672A 1972-08-02 1972-08-02

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US3794453A true US3794453A (en) 1974-02-26

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US00277396A Expired - Lifetime US3794453A (en) 1972-08-02 1972-08-02 Capsule making apparatus

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US (1) US3794453A (enrdf_load_stackoverflow)
JP (1) JPS5827938B2 (enrdf_load_stackoverflow)
AU (1) AU465004B2 (enrdf_load_stackoverflow)
BE (1) BE803120A (enrdf_load_stackoverflow)
BR (1) BR7305854D0 (enrdf_load_stackoverflow)
CA (1) CA1003606A (enrdf_load_stackoverflow)
CH (1) CH559546A5 (enrdf_load_stackoverflow)
DE (1) DE2339059C2 (enrdf_load_stackoverflow)
ES (1) ES417460A1 (enrdf_load_stackoverflow)
FR (1) FR2194410B1 (enrdf_load_stackoverflow)
GB (1) GB1380669A (enrdf_load_stackoverflow)
IT (1) IT990051B (enrdf_load_stackoverflow)

Cited By (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3910183A (en) * 1974-02-28 1975-10-07 Parke Davis & Co Apparatus for offset printing capsules
US4393643A (en) * 1981-09-29 1983-07-19 The Procter & Gamble Company Process for forming a barrier phase
WO1984000919A1 (en) * 1982-09-02 1984-03-15 Scherer Corp R P Hard shell gelatin capsule dipping apparatus and method
US4627808A (en) * 1985-05-31 1986-12-09 Hughes Raymond J Apparatus for making capsule having plural chambers
US4705658A (en) * 1986-04-07 1987-11-10 Capsule Technology International, Ltd. Method for drying gelatin in the manufacture of hard shell gelatin capsules
US4993137A (en) * 1986-05-12 1991-02-19 Shin-Etsu Chemicals Co., Ltd. Method of manufacturing hard capsules
WO1996039292A1 (en) * 1995-06-05 1996-12-12 Gs Technologies, Inc. Method and apparatus for the manufacture or pharmaceutical cellulose capsules
EP0781540A2 (en) 1991-05-31 1997-07-02 Gs Technologies, Inc. Method and apparatus for manufacturing pharmaceutical cellulose capsules - drying the capsule
US5698155A (en) * 1991-05-31 1997-12-16 Gs Technologies, Inc. Method for the manufacture of pharmaceutical cellulose capsules
US5945136A (en) * 1997-04-03 1999-08-31 Technophar Equipment & Service Limited Heating elevator for capsule making machine
US5993185A (en) * 1996-03-21 1999-11-30 Farmacapsulas S.A. Deck plate assemblies for forming capsules
US6000928A (en) * 1997-04-03 1999-12-14 Technophar Equipment & Service Limited Capsule making machine having improved pin bars and air flow characteristics
FR2788778A1 (fr) * 1999-01-25 2000-07-28 Su Heung Capsule Co Ltd Composition pour la fabrication de capsules a enveloppe dure botaniques, leur procede de fabrication et capsules ainsi obtenues
RU2189312C2 (ru) * 1995-12-15 2002-09-20 Инновацион унд Арт ГмбХ Способ изготовления предохранительного средства
CN105326644A (zh) * 2015-12-16 2016-02-17 浙江春宝胶囊有限公司 一种熔胶蘸胶一体化装置
CN106024358A (zh) * 2016-06-27 2016-10-12 国网江苏省电力公司盐城供电公司 一种变压器含浸盘
CN106273141A (zh) * 2016-08-24 2017-01-04 浙江亚利大胶丸有限公司 一种空心胶囊的生产浸胶装置
CN111433546A (zh) * 2017-12-06 2020-07-17 快力胶囊股份有限公司 柱状结构物的干燥装置和柱状结构物的制造方法
CN112336626A (zh) * 2020-11-26 2021-02-09 江西钟山药业有限责任公司 一种胶囊填充机
CN115990971A (zh) * 2022-12-14 2023-04-21 安徽黄山胶囊股份有限公司 一种植物肠溶空心胶囊全自动生产线及其生产方法

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2776224B1 (fr) * 1998-03-20 2000-05-26 Kerlane Pieces de forme minces en fibres minerales, procede et moule pour leur fabrication par aspiration sous vide
CN104586634A (zh) * 2015-01-16 2015-05-06 浙江大之医药胶囊有限公司 全自动胶囊生产线的蘸胶装置
CN104606054B (zh) * 2015-01-16 2019-02-01 浙江大之医药胶囊有限公司 一种全自动胶囊生产线的蘸胶装置
CN105030542B (zh) * 2015-06-16 2016-08-17 安徽黄山胶囊股份有限公司 一种空心胶囊制备装置
CN112240659A (zh) * 2020-10-17 2021-01-19 温州桑盾信息科技有限公司 一种胶囊机安全防护用自动降温机构

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1114325A (en) * 1908-06-15 1914-10-20 Sharp And Dohme Capsule-machine.
US1978829A (en) * 1930-07-21 1934-10-30 Parke Davis & Co Method and apparatus for drying capsules
US3429358A (en) * 1964-09-21 1969-02-25 Howmet Corp Method for manufacture of refractory shell molds

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB360427A (en) * 1930-06-30 1931-10-30 Parke Davis & Co An improved machine for making medicinal capsules and the like
US2575789A (en) * 1948-11-15 1951-11-20 Parke Davis & Co Process and apparatus for manufacturing capsules

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1114325A (en) * 1908-06-15 1914-10-20 Sharp And Dohme Capsule-machine.
US1978829A (en) * 1930-07-21 1934-10-30 Parke Davis & Co Method and apparatus for drying capsules
US3429358A (en) * 1964-09-21 1969-02-25 Howmet Corp Method for manufacture of refractory shell molds

Cited By (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3910183A (en) * 1974-02-28 1975-10-07 Parke Davis & Co Apparatus for offset printing capsules
US4393643A (en) * 1981-09-29 1983-07-19 The Procter & Gamble Company Process for forming a barrier phase
WO1984000919A1 (en) * 1982-09-02 1984-03-15 Scherer Corp R P Hard shell gelatin capsule dipping apparatus and method
US4627808A (en) * 1985-05-31 1986-12-09 Hughes Raymond J Apparatus for making capsule having plural chambers
US4705658A (en) * 1986-04-07 1987-11-10 Capsule Technology International, Ltd. Method for drying gelatin in the manufacture of hard shell gelatin capsules
US5032074A (en) * 1986-05-12 1991-07-16 Shin-Etsu Chemical Co., Ltd. Apparatus for manufacturing hard capsules for medicament use
US4993137A (en) * 1986-05-12 1991-02-19 Shin-Etsu Chemicals Co., Ltd. Method of manufacturing hard capsules
US6337045B1 (en) 1991-05-31 2002-01-08 R. P. Scherer Technologies, Inc. Method for the manufacture of pharmaceutical cellulose capsules
EP0781540A2 (en) 1991-05-31 1997-07-02 Gs Technologies, Inc. Method and apparatus for manufacturing pharmaceutical cellulose capsules - drying the capsule
EP0781541A2 (en) 1991-05-31 1997-07-02 Gs Technologies, Inc. Method and apparatus for manufacturing pharmaceutical cellulose capsules - sizing the capsule
EP0781542A2 (en) 1991-05-31 1997-07-02 Gs Technologies, Inc. Method and apparatus for manufacturing pharmaceutical cellulose capsules - fully gelatinizing
EP0784969A2 (en) 1991-05-31 1997-07-23 Gs Technologies, Inc. Method and apparatus for manufacturing pharmaceutical cellulose capsules - removing capsule from pin
US5698155A (en) * 1991-05-31 1997-12-16 Gs Technologies, Inc. Method for the manufacture of pharmaceutical cellulose capsules
US5750157A (en) * 1991-05-31 1998-05-12 Gs Technologies, Inc. Apparatus for the manufacture of pharmaceutical cellulose capsules
US5756036A (en) * 1991-05-31 1998-05-26 Gs Technologies, Inc. Method for the manufacture of pharmaceutical cellulose capsules
WO1996039292A1 (en) * 1995-06-05 1996-12-12 Gs Technologies, Inc. Method and apparatus for the manufacture or pharmaceutical cellulose capsules
RU2189312C2 (ru) * 1995-12-15 2002-09-20 Инновацион унд Арт ГмбХ Способ изготовления предохранительного средства
US5993185A (en) * 1996-03-21 1999-11-30 Farmacapsulas S.A. Deck plate assemblies for forming capsules
US6000928A (en) * 1997-04-03 1999-12-14 Technophar Equipment & Service Limited Capsule making machine having improved pin bars and air flow characteristics
US5945136A (en) * 1997-04-03 1999-08-31 Technophar Equipment & Service Limited Heating elevator for capsule making machine
FR2788778A1 (fr) * 1999-01-25 2000-07-28 Su Heung Capsule Co Ltd Composition pour la fabrication de capsules a enveloppe dure botaniques, leur procede de fabrication et capsules ainsi obtenues
CN105326644A (zh) * 2015-12-16 2016-02-17 浙江春宝胶囊有限公司 一种熔胶蘸胶一体化装置
CN106024358A (zh) * 2016-06-27 2016-10-12 国网江苏省电力公司盐城供电公司 一种变压器含浸盘
CN106024358B (zh) * 2016-06-27 2019-12-27 国网江苏省电力公司盐城供电公司 一种变压器含浸盘
CN106273141A (zh) * 2016-08-24 2017-01-04 浙江亚利大胶丸有限公司 一种空心胶囊的生产浸胶装置
CN111433546A (zh) * 2017-12-06 2020-07-17 快力胶囊股份有限公司 柱状结构物的干燥装置和柱状结构物的制造方法
EP3719429A4 (en) * 2017-12-06 2021-09-08 Qualicaps Co., Ltd. DRYING DEVICE FOR A COLUMN STRUCTURE, AND METHOD FOR MANUFACTURING A COLUMN STRUCTURE
CN114322474A (zh) * 2017-12-06 2022-04-12 快力胶囊股份有限公司 柱状结构物的干燥装置和柱状结构物的制造方法
CN111433546B (zh) * 2017-12-06 2022-10-25 快力胶囊股份有限公司 柱状结构物的干燥装置和柱状结构物的制造方法
CN112336626A (zh) * 2020-11-26 2021-02-09 江西钟山药业有限责任公司 一种胶囊填充机
CN115990971A (zh) * 2022-12-14 2023-04-21 安徽黄山胶囊股份有限公司 一种植物肠溶空心胶囊全自动生产线及其生产方法

Also Published As

Publication number Publication date
IT990051B (it) 1975-06-20
BR7305854D0 (pt) 1974-08-29
ES417460A1 (es) 1976-03-16
JPS5827938B2 (ja) 1983-06-13
DE2339059C2 (de) 1982-09-30
FR2194410A1 (enrdf_load_stackoverflow) 1974-03-01
FR2194410B1 (enrdf_load_stackoverflow) 1976-04-30
AU465004B2 (en) 1975-09-11
GB1380669A (en) 1975-01-15
CA1003606A (en) 1977-01-18
BE803120A (fr) 1973-12-03
DE2339059A1 (de) 1974-02-14
CH559546A5 (enrdf_load_stackoverflow) 1975-03-14
JPS4950115A (enrdf_load_stackoverflow) 1974-05-15
AU5870573A (en) 1975-02-06

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