US3774600A - Gynaecological surgical device - Google Patents

Gynaecological surgical device Download PDF

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Publication number
US3774600A
US3774600A US00193064A US3774600DA US3774600A US 3774600 A US3774600 A US 3774600A US 00193064 A US00193064 A US 00193064A US 3774600D A US3774600D A US 3774600DA US 3774600 A US3774600 A US 3774600A
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United States
Prior art keywords
cone
apex
cord
tube
cicatrisation
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
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US00193064A
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English (en)
Inventor
M Cognat
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Gambro Industries SAS
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Rhone Poulenc SA
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Assigned to SOCIETE DES INDUSTRIES PLASTIQUES-SODIP reassignment SOCIETE DES INDUSTRIES PLASTIQUES-SODIP ASSIGNMENT OF ASSIGNORS INTEREST. Assignors: RHONE-POULENC S.A.
Assigned to HOSPAL SODIP S.A., A SOCIETE ANONYME, MEYZIEU 69330 7 AVENUE LIONEL TERRAY, LYONS reassignment HOSPAL SODIP S.A., A SOCIETE ANONYME, MEYZIEU 69330 7 AVENUE LIONEL TERRAY, LYONS CHANGE OF NAME (SEE DOCUMENT FOR DETAILS). 2-18-81 Assignors: SOCIETE DES INDUSTRIES PLASTIQUES SODIP
Assigned to HOSPAL INDUSTRIE reassignment HOSPAL INDUSTRIE CHANGE OF NAME (SEE DOCUMENT FOR DETAILS). EFFECTIVE OCT. 4, 1983 Assignors: HOSPAL SODIP S.A.
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Expired - Lifetime legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/42—Gynaecological or obstetrical instruments or methods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/04—Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts

Definitions

  • ABSTRACT A gynaecological surgical device to avoid Fallopian tubes becoming blocked again during cicatrisation following a tuboplasty operation, such device comprising a hollow cone of a flexible sheet material and a cord firmly fixed to the apex of the cone.
  • the device In use after performing a salpingostomy of the blocked portion of a patients Fallopian tube, the device is placed with the apex extending into the cut end of the tube with the cord extending to the abdominal wall.
  • the base edge of the cone is folded around the end of the tube and secured to the tube exterior to prevent blockage during cicatrisation of the tube. When this is completed, the device can be removed simply by pulling the cord.
  • the present invention relates to a gynaecological surgical device intended to facilitate the surgical treatment of female sterility of tubal origin. It relates, more especially, to a surgical device which makes it possible to avoid the ends of the Fallopian tubes becoming blocked again after a tuboplasty operation (in particular, a salpingostomy) as a result of rapid and correct cicatrisation in the open position of the tubes.
  • a tuboplasty operation in particular, a salpingostomy
  • the surgical devices described in US. Pat. Nos. 3,182,662 and 3,349,770 allow tubo-uterine anastomosis to be carried out.
  • the end of the tubes is opened and a surgical device is placed in position which protects the open end until cicatrisation is complete andwhich prevents the tube from becomingblocked again. In order to place such a surgical device in position, it isnecessary to carry out a laparotomy.
  • MULLIGAN W. J., ROCK J. and EASTERD AY C. L. Use of polyethylene in tuboplasty Fertility and Sterility 4 428, 19 53 have in this case proposed a rigid surgical device in-the form of a cone which covers the end of the tubes and which is withdrawn after cicatrisation, after a period of 2 to 3 months, by carrying out a second laparotomy.
  • a surgical device to avoid Fallopian tubes becoming blocked again during cicatrisation following a tuboplasty operation comprising a hollow cone of flexible sheet material and a cord-like member firmly fixed to the apex of the cone.
  • Such a surgical device only requires a single operation (when it is placed in position), it is easily held in position in the patient, it can be withdrawn very easily and it ensures rapid cicatrisation (within a period of l to 3 weeks) of the end of the tubes in the open position.
  • the invention also provides a method of surgically treating female sterility of tubal origin comprising performing a salpingostomy on the blocked portion of a patients Fallopian tube, placing a surgical device according to the invention with the apex of the cone extending into the end of the tube and the cord extending to the abdominal wall, folding the edge of the cone around the end of the tube and securing it to the exterior of the tube to prevent blockage during cicatrisation of the tube.
  • FlGS. l, 3 5, 7, 8 and 9 are schematic perspective views of three embodiments of the device according to the invention.
  • FIGS. 2, 4 and 6 are similar views showing the devices of FIGS. 1, 3 and 5 respectively after being placed in position in the patient.
  • the surgical device shown in FIG. 1 consists of a flexible sheet rolled up in the shape of a cone 1, the angle a at the apex being between 5 and 80 and preferably between 10 and A cord 2 is firmly fixed to the apex 3 of the cone 1, the length of this cord being between 200 and 600 mm, and its diameter being generally between 0.2 and 6 mm.
  • This cord 2 for example consists of polyamide, which gives it a certain flexibility as well as sufficient tensile strength during removal of the device.
  • the cone 1 consists of a sterilisable plastic tolerated by the organism, which is sufficiently flexible that it can easily be folded over on itself and remain in this position when it has been brought thereto when placing the device inposition.
  • Organopolysiloxane elastomers are suitable for this application.
  • the thickness of the wall of the cone 1 is between 0.1 and 0.8 mm, whilst its height is between 20 and 200
  • the cone 1 can, for example, be obtained by the socalled slush-coating technique, that is to say, by depositing successive thin layers of material on a shaping device of the desired shape. It is also possible to obtain the cone from a sheet which is cut and of which the edges 'are joined by welding or gluing.
  • the apex 3 of the cone can be attached to the cord 2 by, for example, passing the cord 2 through the apex 3 ofthe coneand knotting the cord two or three times onto itself atits end which is near the apex of the cone. Then some silicone elastomer, for example, is deposited on the excess thickness formed by the knots and the part of the cord which is outside the cone is pulled gently so that the knotted end comes to lie against the apex of the cone and to stick thereto, either under hot of the cone. 1
  • FIG. 2 shows the device of FIG. 1 after being placed in position.
  • the surgeon carries out a laparotomy and then a salpingostomy (he cuts the end of the blocked tube). He places the device, which has shall cover the tube better. He then attaches the cone 7 l to the end of the tube by making a few stitches (not shown in FIG. 2) using a resorbable material, for example catgut, the resorption time of this material corresponding substantially to the time required for cicatrisation.
  • the cord 2 is thereafter anchored to the abdominal wall 5.
  • the surgeon places an identical surgical device in position in the same manner on the other tube if the blockage is bilateral.
  • the surgical device When sufficient cicatrisation has occurred, which merely requires from about I to 3 weeks (thanks to the flexible cone, which completely covers the end of the tube), the surgical device is withdrawn by simply pulling the cord 2 through the abdominal wall 5 in the manner of a simple drain, without anaesthetic.
  • FIG. 3 represents a preferred embodiment of the surgical device. This comprises all the elements described in the preceding device of FIG. 1, that is to say a cone 6 with a cord fixed firmly to its apex 7. However, the cord of this embodiment passes through the cone practically along its axis and has substantially equal portions (marked 8 and 9), of between 200 and 600 mm, ex-
  • the device of FIG. 3, whilst it can be withdrawn as easily as that of FIG. 1, has the advantage of allowing the cone 6 to be positioned better during the period of cicatrisation and of resorption of the stitches.
  • the part 9 of the cord which is in the tube in effect assists better stability of the device during cicatrisation.
  • This device can be used with advantage in the case where the external and internal portions of one and the same tube are blocked.
  • the cord 9 acts as a cicatrisation tutor for the duct 14 whilst the cone 6 ensures rapid cicatrisation in the open position of the tube.
  • the surgeon can operate as follows: he carries out a laparotomy and then a salpingostomy, he adjusts the part 9 of the cord to the desired length for it to reach the uterine cavity 11, he introduces the part 9 of the cord through the open tube until it can slide no further in the duct, he cuts the duct in two places so as to remove the obstructed part, effects a termino-terminal anastomosis and continues to slide the cord 9 until the cone 6 is in position on the end of the tube. The continuation of the operation is then identical to that previously carried out.
  • FIGS. 5 and 6 Another embodiment of the invention is shown in FIGS. 5 and 6.
  • the cord 17 extending from externally beyond the apex 16 of the cone 15 to the abdominal wall 19 is surrounded by a sheath 20, for example consisting of an organosilicon elastomer.
  • This sheath forms a drain as a result of transverse orifices 21 and 22 located near the apex of the cone 15.
  • This latter device in addition to having the advantages quoted for the device shown in FIGS. 3 and 4, additionally makes it possible to inject, from the abdominal wall 19, any liquid which can, for example, activate cicatrisation or arrest a possible infection.
  • This latter embodiment furthermore has the advantage of making it even easier to withdraw the device because the external diameter of the sheath 20 forming the drain is substantially the same as the cross-section which th cone assumes if it is folded up on itself during its removal.
  • plastics of medical quality which can be sterilised and which do not allow adhesions of human tissues to their surface, whilst being well tolerated by the organism.
  • the cone must have sufficient flexibility that it can easily be folded onto itself and can maintain this position after it has assumed it.
  • the cord must have sufficient tensile strenth after sterilisation to allow the surgical device to be withdrawn; it must alsohave sufficient flexibility to match the shape of the duct of the tube all the way into the uterine cavity (in the case of the devices shown in FIGS. 3 and 5) and to remain as far as possible in the position in which it has been placed.
  • organopolysiloxane elastomers are used for the manufacture of the cone and of the drain.
  • the cone can also be produced from a textile material, for example a polyethylene terephthalate'fabric, which is coated with organopolysiloxane elastomer.
  • the cord can for example be made of polyamide or of polyester.
  • FIG. 7 A further embodiment of the device (FIG. 8) replaces the solid cord by ahollow cord 30 forming a drain and provided with lateral orifices 31 and 32 in the zone located near the apex of the cone 6.
  • FIG. 9 A modification of the deviceof FIG. 3 is shown in FIG. 9 in which a cord 38 extends from the apex of the cone to the abdominal wall, of greater diameter than the part of the cord 39 which extends from thetube into the uterine cavity. This favours the withdrawal of the surgical device, the cross-section of the cord 38 being of greater diameter, for example corresponding substantially to the cross-section which the cone assumes when it is folded up on itself during its withdrawal.
  • EXAMPLE 1 A device corresponding to that shown in FIG. 3, was produced, the cone having an angle of at the apex, being 150 mm high and having a wall thickness of 0.16
  • the cord was passed through the cone 6 at its apex 7 along its axis and then extended on either side of the apex 7 to equal lengths of 500 mm.
  • the cord was 0.5 mm in diameter and consisted of polyamide 6,6, its tensile strength being 45.3 kg/mm before sterilisationand its elongation being 40 percent.
  • the cone was obtained by the slush-moulding technique, that is to say by successively steeping a shaping device into a liquid elastomer until the desired thickness was obtained.
  • a diluted hot-vulcanisable organopolysiloxane elastomer of the same composition as that described in the example of French Patent No. 1,499,305, was used.
  • the shaping device used was of polished stainless steel. 1
  • the article was vulcanised in a ventilated oven at 140C for 30 minutes and was then reheated for 18 hoursat between 180 and 200C.
  • the cord was first of all passed through the end of the cone and. was knotted substantially in its middle, on the inside of the cone. A ball of undiluted silicone elastomer was placed around the knot and was shaped into an olive-shaped knob. The part of the cord which was outside the cone was then pulled until the knob obtained pressed against the apex of the cone. The whole was vulcanised at 180 200C for 4 hours.
  • This prosthesis was heat-sterilised at 180C for 4 hours.
  • the tension required to break the cord was then 16.6 kg/mm and the elongation of the cord was 17 percent.
  • the same device can be sterilised with y rays.
  • the tension to break the cord was then 41 kg/mm*, its elongation being 36 percent, after an irradiation under 2.5 Megarads.
  • EXAMPLE 2 A device as shown in FIG. 5, was made starting from a device identical to that described in Example 1, of the same dimensions and made of the same materials.
  • a drain of heat-vulcanisable organopolysiloxane elastomer of 3 mm internal diameter, 5 mm external diameter and 300 mm length was added.
  • the distal end of the drain was provided with two pairs of lateral oridevice to avoid Fallo- I a single hollow cone of flexible sheet material having an apex and a base edge and closed at its apex, ane a cordlike member fixed firmly to the apex of the cone.
  • a device .as claimed in claim 1 and further comprising a drain tube sheathing the cord and means defining lateral orifices in the tube located near the apex of the cone.
  • drain tube is formed of organosilicon elastomer.
  • a device as claimed in claim 1, wherein said cord comprises a first portion extending externally beyond the apex of the cone and a second portion extending through the interior of the cone.
  • a device as claimed in claim 1, wherein the apex angle of the cone is between 5 and 80, wherein the height of the cone is between 20 and 200 mm. and wherein the wall thickness of the cone is between 0 1 and 0-8 mm.
  • a method of surgically treating female sterility of tubal origin comprising the steps of performing a salpingostomy of the blocked portion of the patients fallopian tube, providing a surgical device comprising a single hollow cone of flexible sheet material having an apex and a base edge and closed at its apex with a cord-like-member fixed firmly to the apex of the cone, placing said device with the apex of the cone extending intothe end of the fallopian tube and extending the cord like member from the inside of said cone to the abdominal wall, folding the base edge of the cone around the end of said tube and securing it to the exterior of the tube to hold it in place to prewardly to'the abdominal wall;

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Reproductive Health (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Vascular Medicine (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Pulmonology (AREA)
  • Cardiology (AREA)
  • Transplantation (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Prostheses (AREA)
  • Materials For Medical Uses (AREA)
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US00193064A 1970-10-27 1971-10-27 Gynaecological surgical device Expired - Lifetime US3774600A (en)

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FR7038735A FR2110697A5 (de) 1970-10-27 1970-10-27

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US00193064A Expired - Lifetime US3774600A (en) 1970-10-27 1971-10-27 Gynaecological surgical device

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US (1) US3774600A (de)
JP (1) JPS5026878B1 (de)
BE (1) BE774513A (de)
CH (1) CH535574A (de)
DK (1) DK126158B (de)
FR (1) FR2110697A5 (de)
GB (1) GB1326847A (de)
IT (1) IT961517B (de)
NL (1) NL156591B (de)
SE (1) SE370862B (de)

Cited By (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4288012A (en) * 1979-09-06 1981-09-08 Doak Roni K Coathanger suspender
US5273054A (en) * 1991-09-19 1993-12-28 Walker John W Permanent diaphragm
US6145505A (en) * 1995-06-07 2000-11-14 Conceptus, Inc. Electrically affixed transcervical fallopian tube occlusion devices
US6526979B1 (en) 1995-06-07 2003-03-04 Conceptus, Inc. Contraceptive transcervical fallopian tube occlusion devices and methods
US6709667B1 (en) 1999-08-23 2004-03-23 Conceptus, Inc. Deployment actuation system for intrafallopian contraception
US6763833B1 (en) 1999-08-23 2004-07-20 Conceptus, Inc. Insertion/deployment catheter system for intrafallopian contraception
US20050061329A1 (en) * 2003-09-18 2005-03-24 Conceptus, Inc. Catheter for intrafallopian contraceptive delivery
US8048086B2 (en) 2004-02-25 2011-11-01 Femasys Inc. Methods and devices for conduit occlusion
US8048101B2 (en) 2004-02-25 2011-11-01 Femasys Inc. Methods and devices for conduit occlusion
US8052669B2 (en) 2004-02-25 2011-11-08 Femasys Inc. Methods and devices for delivery of compositions to conduits
US9238127B2 (en) 2004-02-25 2016-01-19 Femasys Inc. Methods and devices for delivering to conduit
US9554826B2 (en) 2008-10-03 2017-01-31 Femasys, Inc. Contrast agent injection system for sonographic imaging
US10070888B2 (en) 2008-10-03 2018-09-11 Femasys, Inc. Methods and devices for sonographic imaging

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT379073B (de) * 1984-06-05 1985-11-11 Zech Herbert Kammer zur aufnahme eines von einem menschlichen eierstock abgeschiedenen ei's und zur weiterleitung desselben in die gebaermutter

Citations (6)

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US65903A (en) * 1867-06-18 Improved pessary
US1040404A (en) * 1911-11-01 1912-10-08 William E Poindexter Pile-truss.
US1982001A (en) * 1933-01-19 1934-11-27 Earle C Haas Pessary
US3182662A (en) * 1962-07-25 1965-05-11 Vithal N Shirodkar Plastic prosthesis useful in gynaecological surgery
US3307552A (en) * 1963-03-25 1967-03-07 Lillian T Strawn Catheter plug and shield device
US3467090A (en) * 1967-05-03 1969-09-16 Phillip B Zollett Self-retaining occlusive stem pessary

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US65903A (en) * 1867-06-18 Improved pessary
US1040404A (en) * 1911-11-01 1912-10-08 William E Poindexter Pile-truss.
US1982001A (en) * 1933-01-19 1934-11-27 Earle C Haas Pessary
US3182662A (en) * 1962-07-25 1965-05-11 Vithal N Shirodkar Plastic prosthesis useful in gynaecological surgery
US3307552A (en) * 1963-03-25 1967-03-07 Lillian T Strawn Catheter plug and shield device
US3467090A (en) * 1967-05-03 1969-09-16 Phillip B Zollett Self-retaining occlusive stem pessary

Cited By (57)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4288012A (en) * 1979-09-06 1981-09-08 Doak Roni K Coathanger suspender
US5273054A (en) * 1991-09-19 1993-12-28 Walker John W Permanent diaphragm
US8356599B2 (en) 1995-06-07 2013-01-22 Conceptus, Inc. Occlusion devices and methods
US8327852B2 (en) 1995-06-07 2012-12-11 Conceptus, Inc. Occlusion devices and methods
US6526979B1 (en) 1995-06-07 2003-03-04 Conceptus, Inc. Contraceptive transcervical fallopian tube occlusion devices and methods
US6634361B1 (en) 1995-06-07 2003-10-21 Conceptus, Inc. Contraceptive transcervical fallopian tube occlusion devices and methods
US6684884B2 (en) 1995-06-07 2004-02-03 Conceptus, Inc. Contraceptive transcervical fallopian tube occlusion devices and methods
US6705323B1 (en) 1995-06-07 2004-03-16 Conceptus, Inc. Contraceptive transcervical fallopian tube occlusion devices and methods
US7921848B2 (en) 1995-06-07 2011-04-12 Conceptus, Inc. Contraceptive transcervical fallopian tube occlusion devices and methods
US6176240B1 (en) 1995-06-07 2001-01-23 Conceptus, Inc. Contraceptive transcervical fallopian tube occlusion devices and their delivery
US7686020B2 (en) 1995-06-07 2010-03-30 Conceptus, Inc. Contraceptive transcervical fallopian tube occlusion devices and methods
US6145505A (en) * 1995-06-07 2000-11-14 Conceptus, Inc. Electrically affixed transcervical fallopian tube occlusion devices
US8171936B2 (en) 1995-06-07 2012-05-08 Conceptus, Inc. Contraceptive transcervical fallopian tube occlusion devices and methods
US8066007B2 (en) 1995-06-07 2011-11-29 Conceptus, Inc. Contraceptive transcervical fallopian tube occlusion devices and their delivery
US7428904B2 (en) 1995-06-07 2008-09-30 Alien Technology Corporation Contraceptive transcervical fallopian tube occlusion devices and their delivery
US8733361B2 (en) 1995-06-07 2014-05-27 Bayer Essure Inc. Occlusion devices and methods
US8733360B2 (en) 1997-09-24 2014-05-27 Bayer Essure Inc. Occlusion devices and methods
US8613282B2 (en) 1997-09-24 2013-12-24 Conceptus, Inc. Occlusion devices and methods
US7591268B2 (en) 1999-08-23 2009-09-22 Conceptus, Inc. Deployment actuation system for intrafallopian contraception
US20050232961A1 (en) * 1999-08-23 2005-10-20 Conceptus, Inc. Deployment actuation system for intrafallopian contraception
US9597224B2 (en) 1999-08-23 2017-03-21 Bayer Healthcare Llc Deployment actuation system
US8381733B2 (en) 1999-08-23 2013-02-26 Conceptus, Inc. Deployment actuation system
US7506650B2 (en) 1999-08-23 2009-03-24 Conceptus, Inc. Deployment actuation system for intrafallopian contraception
US7237552B2 (en) 1999-08-23 2007-07-03 Conceptus, Inc. Insertion/deployment catheter system for intrafallopian contraception
US8079364B2 (en) 1999-08-23 2011-12-20 Conceptus, Inc. Deployment actuation system for intrafallopian contraception
US7934504B2 (en) 1999-08-23 2011-05-03 Conceptus, Inc. Deployment actuation system for intrafallopian contraception
US8695604B2 (en) 1999-08-23 2014-04-15 Bayer Essure Inc. Deployment actuation system
US6709667B1 (en) 1999-08-23 2004-03-23 Conceptus, Inc. Deployment actuation system for intrafallopian contraception
US20040163650A1 (en) * 1999-08-23 2004-08-26 Conceptus, Inc. Deployment actuation system for intrafallopian contraception
US6763833B1 (en) 1999-08-23 2004-07-20 Conceptus, Inc. Insertion/deployment catheter system for intrafallopian contraception
US8584679B2 (en) 1999-08-23 2013-11-19 Conceptus, Inc. Deployment actuation system
US20050061329A1 (en) * 2003-09-18 2005-03-24 Conceptus, Inc. Catheter for intrafallopian contraceptive delivery
US8316854B2 (en) 2004-02-25 2012-11-27 Femasys Inc. Methods and devices for conduit occlusion
US9220880B2 (en) 2004-02-25 2015-12-29 Femasys Inc. Methods and devices for delivery of compositions to conduits
US8324193B2 (en) 2004-02-25 2012-12-04 Femasys Inc. Methods and devices for delivery of compositions to conduits
US8316853B2 (en) 2004-02-25 2012-11-27 Femasys Inc. Method and devices for conduit occlusion
US8695606B2 (en) 2004-02-25 2014-04-15 Femasys Inc. Methods and devices for conduit occlusion
US8726906B2 (en) 2004-02-25 2014-05-20 Femasys Inc. Methods and devices for conduit occlusion
US8052669B2 (en) 2004-02-25 2011-11-08 Femasys Inc. Methods and devices for delivery of compositions to conduits
US8048101B2 (en) 2004-02-25 2011-11-01 Femasys Inc. Methods and devices for conduit occlusion
US9034053B2 (en) 2004-02-25 2015-05-19 Femasys Inc. Methods and devices for conduit occlusion
US10292732B2 (en) 2004-02-25 2019-05-21 Femasys, Inc. Methods and devices for conduit occlusion
US9238127B2 (en) 2004-02-25 2016-01-19 Femasys Inc. Methods and devices for delivering to conduit
US9308023B2 (en) 2004-02-25 2016-04-12 Femasys Inc. Methods and devices for conduit occlusion
US9402762B2 (en) 2004-02-25 2016-08-02 Femasys Inc. Methods and devices for conduit occlusion
US8336552B2 (en) 2004-02-25 2012-12-25 Femasys Inc. Methods and devices for conduit occlusion
US8048086B2 (en) 2004-02-25 2011-11-01 Femasys Inc. Methods and devices for conduit occlusion
US9839444B2 (en) 2004-02-25 2017-12-12 Femasys Inc. Methods and devices for conduit occlusion
US11779372B2 (en) 2004-02-25 2023-10-10 Femasys Inc. Methods and devices for conduit occlusion
US10111687B2 (en) 2004-02-25 2018-10-30 Femasys, Inc. Methods and devices for conduit occlusion
US9554826B2 (en) 2008-10-03 2017-01-31 Femasys, Inc. Contrast agent injection system for sonographic imaging
US10258375B2 (en) 2008-10-03 2019-04-16 Femasys, Inc. Methods and devices for sonographic imaging
US10172643B2 (en) 2008-10-03 2019-01-08 Femasys, Inc. Contrast agent generation and injection system for sonographic imaging
US11154326B2 (en) 2008-10-03 2021-10-26 Femasys Inc. Methods and devices for sonographic imaging
US11648033B2 (en) 2008-10-03 2023-05-16 Femasys Inc. Methods and devices for sonographic imaging
US10070888B2 (en) 2008-10-03 2018-09-11 Femasys, Inc. Methods and devices for sonographic imaging
US11980395B2 (en) 2008-10-03 2024-05-14 Femasys Inc. Methods and devices for sonographic imaging

Also Published As

Publication number Publication date
NL7114360A (de) 1972-05-02
FR2110697A5 (de) 1972-06-02
CH535574A (fr) 1973-04-15
NL156591B (nl) 1978-05-16
DE2153612B2 (de) 1975-09-18
GB1326847A (en) 1973-08-15
IT961517B (it) 1973-12-10
SE370862B (de) 1974-11-04
JPS5026878B1 (de) 1975-09-03
DE2153612A1 (de) 1972-05-04
BE774513A (fr) 1972-04-26
DK126158B (da) 1973-06-18

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