US3770027A - Manifold liquid distributor - Google Patents

Manifold liquid distributor Download PDF

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Publication number
US3770027A
US3770027A US00216050A US3770027DA US3770027A US 3770027 A US3770027 A US 3770027A US 00216050 A US00216050 A US 00216050A US 3770027D A US3770027D A US 3770027DA US 3770027 A US3770027 A US 3770027A
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Prior art keywords
conduits
liquid
collection tube
conduit
tube
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Expired - Lifetime
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US00216050A
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English (en)
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J Guigan
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Individual
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Individual
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Priority claimed from FR7100378A external-priority patent/FR2126914B1/fr
Priority claimed from FR7106311A external-priority patent/FR2128022B2/fr
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N31/00Investigating or analysing non-biological materials by the use of the chemical methods specified in the subgroup; Apparatus specially adapted for such methods
    • G01N31/22Investigating or analysing non-biological materials by the use of the chemical methods specified in the subgroup; Apparatus specially adapted for such methods using chemical indicators
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00Sampling; Preparing specimens for investigation
    • G01N1/02Devices for withdrawing samples
    • G01N1/10Devices for withdrawing samples in the liquid or fluent state
    • G01N1/18Devices for withdrawing samples in the liquid or fluent state with provision for splitting samples into portions
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00Sampling; Preparing specimens for investigation
    • G01N1/02Devices for withdrawing samples
    • G01N1/10Devices for withdrawing samples in the liquid or fluent state
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00Sampling; Preparing specimens for investigation
    • G01N1/02Devices for withdrawing samples
    • G01N1/10Devices for withdrawing samples in the liquid or fluent state
    • G01N1/14Suction devices, e.g. pumps; Ejector devices
    • G01N2001/1445Overpressure, pressurisation at sampling point
    • G01N2001/1454Positive displacement, piston

Definitions

  • the present invention relates to a manifold distributor of a measured liquid substance from a first container in which it is stored to a plurality of secondary containers.
  • the aim of the present invention is to provide a distributor of simple structure, which is low in cost and provides rapid and reliable operation.
  • Another aim of the invention is the simultaneous distribution of measured amounts of liquid into each of the secondary containers, these amounts being preferably small and accurately measured.
  • the present invention has as its object a manifold distributor of a liquid in measured amounts comprising a first tube for collecting the liquid to be distributed and a plurality of secondary tubes known as work tubes and intended for receiving the measured amounts of the liq uid, characterized in that it also comprises a plurality of capillary conduits provided with throttling means, a piston action cooperating with the collection tube to ensure the filling of the conduits from the collection tube via a first end of the former and at least as far as the throttling means, venting means of the first end of the conduits, and centrifugal means cooperating with the work tubes to ensure the transfer into the latter of the liquid contained in the conduit.
  • FIG. 1 is a sectional view along an axial plane of the device according to the invention.
  • FIG. 2 shows a plan view of the unit for collecting the measured amounts of the liquid
  • FIG. 3 is a diagrammatic plan view of an embodiment of the retention member
  • FIGS. 4 and 5 show two embodiments of one of the members of FIG. 1; v
  • FIG. 6 is a sectional view alongan axial plane of an embodiment with respect to FIG. 1;
  • FIG. 7 is an enlarged partial sectional view of a work tube and the conduit associated with it according to an embodiment of the invention.
  • FIGS. 8, 9 and 10 are sectional views of three respective positions of the work tube and the conduit associated with it as shown in FIG. 7.
  • the manifold distributor comprises essentially three parts intended to work together'to ensure a simultaneous distribution of measured amounts of a same liquid.
  • the manifold distributor comprises a storage'tube 1 of the liquid, known hereafter as the tube for coIlecting the liquid of which measured amounts are to be distributed, a member for the retention of measured amountsof the liquid, the member ensuring the drawing off of the liquid and its distribution in measured amounts, and aplurality of storage tubes 30 for the measured amounts of the liquid, the tubes being known hereinafter as work tubes.
  • the collection tube 1 has a constant crosssection.
  • the tube 1 is open at its upper end.
  • the member 20 consists of a hollow tube 2 of slight section in relation to that of the collection tube 1, provided at a first open end intended to penetrate into the collection tube 1, with a collar 3 of the same external diameter as the internal diameter of the collection tube 1. Blades 4 dis posed along the length of tube 2 are intended to ensure the guiding of the latter within the collection tube 1.
  • the second end of tube 2 opens into a central chamber 5 of spherical shape in FIG 1, the outer wall of which is provided, over a section along a plane perpendicular to the axis of the tube 2, with a plurality of regularly disposed orifices 6 into which issue a plurality of conduits 9 having a very small section.
  • a tube 7 disposed in the extended part of tube 2 has a first end which also debouches into the central chamber 5. The second end of tube 7 widens out into 8.
  • conduits 9 ending in the orifices 6 of the central chamber 5 are disposed radially with respect to chamber 5.
  • These conduits 9 are constituted by tubes, for example, capillary tubes.
  • Each comprises a throttling means 10, the volume between the end opening into one of the orifices 6 and the section of the lowest diameter of the throttling means being calibrated with precisron.
  • the portions between the second ends of the conduit 9 and the throttling means are bent outwards, the vertices of the bends being at a similar or slightly higher level than that of the funnel-shaped part 8 of the tube 7.
  • the second ends of the conduits 9 are regularly distributed on a circumference having as an axis the axis of the tube 2 or 7. These ends are intended to issue respectively into a plurality of work tubes 30 joined one to the other by means of an annular bearer element 31 on which they are regularly spaced, the distance between the openings of two successive work tubes 30 being equal to that between the second ends of two successive conduits 9.
  • Each of the work tubes 30 is closed initially by a piece 17, the central part of whichiforms an easily pierceable disphragm 12.
  • the piece 17 limits a recess 18 ensuring the guiding into position of a piece 13 in which is sunk the second end of the corresponding conduit 9 which is intended to open into the relevant work tube 30.
  • This piece 13 has a section end which is substantially equal to that of the recess 18, the. end terminating in a tapered point turned towards the diaphragm 12 to be pierced.
  • a circular band 14 of cardboard or the like may form a cross-piece between the piece. 13 andeach corre sponding diaphragm l2 and may thus isolate the conical end of the piece 13 from the diaphragm 12 before utilization of the device.
  • the band is removed by using a circular tearing movement. An outwardly projecting portion of the band allows it to be gripped for this purpose.
  • conduits 9 are inclined with respect to the axis of the tube 2.
  • the work tubes 30 have, with respect to an axis passing through the vertex of the bend and parallel to the axis of the tube 2, an inclination which is substantially symmetrical with that of the conduit 9 with which they are respectively associated.
  • the liquid to be distributed into the tubes 30 is collected in tube 1.
  • the device described above is held horizontally; the tube 1 is positioned onto the central tube 2 of the device so as to establish a connection between the collection tube 1 and the central chamber 5.
  • the collar 3 adopts the role of a piston and the liquid rises in tube 1 towards chamber 5.
  • the liquid rises in the conduit 9; either by capillary attraction as soon as a sufficient amount of the liquid reaches the chamber 5, the liquid rises as far as the level of the throttling means solely by virtue of the capillary force; or by the action of the pressure maintained by continuing to push the collection tube 1 in the direction of the arrow 11. In this case, the level of the liquid is raised to the level of the throttling means 10 in the conduit 9 and even beyond this point.
  • the liquid rises to the same level in the tube 7 and reaches the widened part 8 intended to control the maximum level attained in the conduits 9 so that the liquid will in no event rise above the level of the bend of each conduit 9 and flow over the ends of the conduit 9.
  • each conduit 9 contains a measured amount of the liquid between its lower end and the throttling means.
  • the device is then rotated about its symmetry axis (the axes of the tubes 2 and 7),either by hand or with the aid of a small centrifuge, which is not shown, and on which is mounted the end of the central tube 2 removed from the collection tube 1.
  • the amounts of liquid contained in the conduit 9 pass from these conduits into the corresponding work tubes 30 where they are mixed if necessary with the solvent, a reagent or a known quantity of any other liquid or solid substance placed in the work tubes.
  • Each work tube thus receives simultaneously an accurately measured amount of liquid.
  • the plurality of work tubes thus receives simultaneously an accurately measured amount of liquid.
  • measured amounts of liquid will be identical from one tube to another.
  • FIG. 1 On the lefthand side of FIG. 1 is shown the end of one of the conduits 9 discharging into the inside of the corresponding work tube 30, the diaphragm 12 having been pierced, the grooves 15 and 16 thus bringing the inside of the tube into contact with the outside of the conduit.
  • the end of one of the conduits 9 shown on the righthand side of FIG. 1 has not pierced the corresponding tube 30 and is thus not in contact with the inside of this work tube.
  • collection tube 1 is of a known conventional type.
  • the member 20 for the drawing off and distribution of measured amounts of liquid may be obtained, for example, by superposing two half shells, a lower shell 21 an an upper shell 22 having on their opposing faces grooves which complement each other to form the interior parts of the conduit 9 and the central chamber 5 when the two half shells 21 and 22 are assembled in a sealed manner at least along the edges of these grooves.
  • the lower half shell 21 comprises the lower central tube 2 fitted with the collar 3 and the blades 4 while the upper half shell 22 comprises the upper central tube 7, the widened upper part 8 of the central tube 7 preferably being a part connected to the tube 7.
  • the work tubes 30 which are integrally linked to one another by an annular bearer element 31 and which are intended to receive measured amounts of the liquid may be formed, as shown in FIG. 2, by a series of regularly spaced cavities in a crown forming the bearer element 31.
  • the crown 31 is an inclined generatrix.
  • the cavities defined in the crown 31 are inclined with respect to the axis of the crown 31, the centersv of the openings of the tubes 30 being regularly distributed on a circle having a lower diameter than that on which the central part of their respective bases are regularly distributed.
  • the openings of the cavities or work tubes 30 are sealed by a flat annular piece 19 having on one face, as shown in FIG.
  • the grooves 16 which are intended to cooperate with the grooves 15 are cut in those portions of the piece 19 limiting the recesses 18. These grooves may be seen in FIG. 1 and are intended for the venting of the tubes 30 when the ends of the conduit 9 penetrate into these tubes.
  • FIG. 3 is a schematic view of a variant of an embodiment of FIG. 1.
  • the capillary conduits 9 that penetrate into the central chamber 5 instead of being radially disposed as described with respect to FIG. 1, are curved inward in the form of a spiral so as to present greater capacities with a similar load or identical capacities with a reduced load.
  • the conduits 9 have merely been schematized by the perforated lines which refer to the capillar conduits. This form an disposition of the conduits 9 also render possiblia for the centrifugation, the use of the force of inertia at the start of the rotation of the displacement of the columns of liquid to be distributed into the work tubes 30.
  • the liquid may be discharged from the collection tube 1, not by pushing this tube 1 in the direction of the arrow 11 of FIG. 1, but by screwing it onto the lower central tube 2.
  • This embodiment does not involve any modification to the operating principle given with respect to FIG 1.
  • the lower central tube 2 has an outer thread 24 and the collection tube 1 has an internal screw cutting 25.
  • the outer diameter of the central tube 2 is substantially equal to that of the collection tube.
  • the collection tube screws onto the central tube 2 which acts as a plunger. The liquid is then pushed in proportion to tube 1 into tube 2 which has a reduced internal section in relation to thatof tube 1..
  • FIG. 4 discloses the central tube 2 carrying a filter 26 on its lower part. It is obvious that the lower part of the tube 2 in the embodiment given in FIG. I may be provided with such a filter.
  • the filling of the conduits 9 and the measuring of the amounts of the liquid to be subsequently transferred into the respective work tubes 30 are effected in two stages corresponding to the pushing movement of tube 1 when the central tube 2 penetrates further into tube 1 and to the retraction of the central tube 2 from the collection tube 1.
  • FIG. 5 discloses another embodiment of the collection tube 1 permitting a simplified method of operation.
  • the collection tube 1 has a lower cylindrical part 41 and an upper part 42 which is frustoconical and then cylindrical with a larger section than that of the lower part 41.
  • the opening 43 of this tube has the same diameter as that of the lower part 41.
  • the tube is fitted with blades 44 extending in such a way as to align approximately the edges of the openings 43 and the wall of the part 41.
  • the lower part 41 is extended by a portion45 forming the base of the tube. This portion 45 is slightly larger in diameter than that of the part 41.
  • the drawing off and distribution member is similar to constant transversal cross-section.
  • Theend of this'central tube which is intendedto penetrate into the collection tube 1' is fitted with a collar such as 3 which forms the piston.
  • the outer-diameter of this collar is substantially equal to that of the opening 43 or the part 41 of the collection tube.
  • the lower control tube 2 may, as shown in FIG. vl, be provided with guide blades such as 4.
  • the piston 3 continues to descend in the collection tube and at the end of its course reaches the part forming the base of the collection tube. As the piston is lower in height than that of the portion 45, the collar 3 fitted on the end of the central tube 2 no longer forms a piston which has the effect of placing in contact the volumes of liquid contained in the parts of the tube 1 on the one hand with the liquid of the collar 3 on the other. The level ofliquid in the central tube 7 descends.
  • the level of liquid descends to the level of the smallest section of the throttling means, while the liquid rises in the collection tube as all the liquid flows from the central tube 7 of the central chamber 5 and the lower central tube 2.
  • the measured amounts of liquid are thus contained in the portions of the conduits 9 lying between their ends opening into the central chamber 5 and the throttling means.
  • the collection tube can then be centrifuged with the unit comprising the conduits 9. The edge at the level of the opening prevents overflow of the liquid during the distribution of the measured amounts of liquid into the respective work tubes.
  • FIG. 6 shows another variant of an embodiment of the collection tube 1 and the member 20 for the draw ing of measured amounts of liquid.
  • the collection tube 1 is similar to that shown in FIG. 5. It comprises a lower cylindrical part 51 having a smaller section than upper part 52.
  • the lower part of the part 51 bears the base of the collection tube.
  • the base of thtube comprises a substantially conical stud 56 disposed substantially in its center.
  • the part 52 is cylindrical at the level of the opening 53 of the tube and frustoconical to permit connection with the part 51 having an upper section smaller than part 52.
  • Part 52 is also provided with blades 54 extending towards the inside of the tube and coming into alignment with the walls of the part 51.
  • the member 20 comprises the capillary conduits 9 but in this embodiment as compared to that of FIG. 1, the conduits 9 are bent at 69 such that the lower part of each of these is vertical. All the lower vertical parts of the conduits 9 extend to the end of the central tube 62 (analogous to the central tube 2 of FIG. 1). At its lower end, the group of vertical parts of the conduits 9 is provided with a collar 63 having an outer diameter which is substantially equal to the diameter of the cross-section of partSl of the collection tube, whereas the lower end of the central tube 62 is closed by a sealed diaphragm 64.
  • the second end of the central tube 62 is in contact with the atmosphere. For this reason, the second end of the tube 62 emerges either in the lower part 67 of the,
  • the level of the part 41 is calculated so that the inner spaceformed by the median parts of the conduits 9.
  • the collar'63 is introduced into the collectiontube 1.
  • the part 51 having a constant but smaller section thanlthat of thepart 52, itadopts the role of a piston.
  • the liquid imprisoned in the part 51 below the piston rises in the conduits 9 under the influence of the pressure as the collar 63 descends in the tube 1.
  • the volume of the part 51 of the collection tube is selected so that it is equal or slightly greater than the sum of the volumes of the liquid in the parts of the capillary conduits lying between their lower ends and the throttling means 10.
  • the conical bussing 56 pierces the diaphragm 64 initially sealing the central tube 62.
  • the columns of liquid in the conduits 9 thus come into contact with the atmosphere.
  • the level of liquid descends in the conduits 9 to the level of the throttling means 10.
  • the collection tube is then withdrawn and the group 20 is then centrifuged to obtained distribution of the measured amount of the liquid in the work tubes.
  • the collection tube and/or the retention member 20 of the measured amounts of liquid and/or the work tubes are preferably of transparent plastic materials.
  • the work tubes may contain initially reagents in the form of a liquid or solid or absorbed, for example, in blotting paper, to allow for direct analysis of the liquid distributed in the work tubes by direct examination of the colored reactions or by comparing these reactions with a colored screen.
  • the work tube 117 comprises two superimposed compartments 101 and 102 closed respectively by a piece 105 fitted with a pierceable diaphragm 106 and a piece 103 fitted with a pierceable diaphragm 104.
  • the pierceable diaphragm 106 is disposed, for example, at the bottom ofa cylindrical hole 112 made in the piece 105.
  • the conduit 100 comprises a channel 107 and is bent at 113 at the level of its end, towards the outside of the retention unit.
  • the end of the channel 107 discharges through a conical point 108 disposed facing the work tube 117.
  • the conical point 108 is provided with a neck 109, which is preferably sharp.
  • the neck 109 of the point 108 is intended to ensure the venting of the upper compartment 101 and the bringing into contact of the compartment with the adjacent compartment 102.
  • the superimposed cross-piece 110 and 111 are applied between a plane face 118 of the conduit 100 and a plane face of the piece 105 to limit the course of the piece 108 and to keep the neck 108 at predetermined levels in the work tube 117.
  • the crosspiece 111 and 110 are common to all the tubes 117 of the manifold distributor and consist of circular bands which may be removed at the time of use by a circular movement.
  • Each of the bands may be provided with a part which is not shown but which projects outward to facilitate gripping the band.
  • Compartment 101 is first partially filled with a first reagent 114 and compartment 102 with a second reagent ll5 (see FIG. 8).
  • the plane face 118 of the conduit 100 abuts against the cross-pieces 110 and 111 and the end of the conical point 108 is disposed slightly above the diaphragm 106 closing the compartments 101.
  • a first phase (see FIG. 9), the cross-piece 111 is removed and pressure is applied to the bend 113 in the direction of the arrow 120.
  • the face 118 of the conduit 100 ab uts on the cross-piece 110.
  • the end of the com cal point 108 tears the diaphragm 106 and penetrates intocompartment 101.
  • the beveled neck 109 ensures venting of this compartment.
  • the liquid contained in the channel 107 is injected by centrifuging according to arrow 121 into compartment 101 and is mixed with the reagent 114. 122 is the resultant mixture thus obtained.
  • the cross-piece is removed (see FIG. 10) and pressure is applied to the bend 113 in the direction of the arrow 130.
  • the face 118 comes to rest against the upper face of the piece 105.
  • the end of the conical point 118 tears the diaphragm 104 and penetrates into compartment 102.
  • the neck 109 102 ensures contact between the two compartments.
  • the mixture 122 flows in the direction of the arrow 131 into the reagent 115.
  • the new mixture obtained is designated by 132.
  • the tube 107 which is now empty of liquid, ensures venting of the compartment 102.
  • the work tube 117 may comprise any number of superimposed compartments connected, for example, to a plurality of cross-piece.
  • the reagents may be in liquid or solid form.
  • An apparatus for distributing liquid in discrete measured quantities comprising:
  • a collection tube for holding the liquid to be distributed
  • the means for forcing the liquid from the collection tube comprising means for moving the collection tube relative to the conduits to produce a piston action on the liquid in the collection tube thereby forcing the liquid into the conduits.
  • the means for forcing the liquid from the collection tube includes a plunger conduit connected to each of the conduits that receive a measured quantity of liquid and wherein, at least a portion of the outside diameter of the plunger conduit corresponds approximately to at least a portion of the inside diameter of the collection tube.
  • the collection tube has a central narrow position of the same inside diameter as the outside diameter of the plunger conduit with the upper and lower portions of the collection tube having larger diameters.
  • conduits extend to the bottom of the plunger conduit, the plunger conduit having a vent conduit sealed with a diaphragm and the collection tube having a piercing stud located on its inside surface for piercing the diaphragm.
  • conduits are conically arranged about the collection tube and the work tubes are arranged approximately perpendicular to the plane of the cone.
  • conduits terminate attheir radially outer ends, in a sharp puncturing tip and the work tubes have a sealing diaphragm acros their surface designated to be punctured by the conduit tips.
  • the means for venting includes a groove adjacent the puncturing tip of each conduit.
  • conduits are bent approximately before connection with the work tubes but after the throttling means.
  • An apparatus as claimed in claim 1 further comprising a ring portion for holding the work tubes at circumferentially spaced positions.
  • conduits are arranged in a conical plane and spiral outward fro the collection tube.
  • the work tubes are divided into two liquid retaining portions by a diaphragm, the top portion adapted to hold one reactant while the bottom is adapted to hold another reactant.
  • the conduits terminate at their radial outer ends in a sharp tip
  • the work tubes have an outer and inner sealing diaphragm spaced axially from each other and a spacer is provided between said conduits and said tubes for limiting the respective tip of each conduit to pierce only the outer diaphragm when the outer ends of the tubes are connected to the conduits.

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Pathology (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Hydrology & Water Resources (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
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US00216050A 1971-01-07 1972-01-07 Manifold liquid distributor Expired - Lifetime US3770027A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR7100378A FR2126914B1 (ja) 1971-01-07 1971-01-07
FR7106311A FR2128022B2 (ja) 1971-02-24 1971-02-24

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US (1) US3770027A (ja)
JP (1) JPS5232272B1 (ja)
CA (1) CA960193A (ja)
DE (1) DE2200730C3 (ja)
GB (1) GB1330994A (ja)
NL (1) NL164133C (ja)
SE (1) SE384271B (ja)

Cited By (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3870014A (en) * 1973-05-24 1975-03-11 Corning Glass Works Liquid and aerosol collecting device
US3986534A (en) * 1974-07-30 1976-10-19 Intertechnique S.A. Device for measuring and dispensing fractionary volumes of liquid samples
US4154793A (en) * 1977-08-18 1979-05-15 Jean Guigan Device for conditioning a sample of liquid for analyzing
US4323364A (en) * 1979-10-31 1982-04-06 Michael Scherz Method of and apparatus for examining substances and mixtures of substances
FR2522812A1 (fr) * 1982-03-05 1983-09-09 Guigan Jean Procede pour delivrer de tres faibles doses a partir d'un echantillon liquide et dispositif pour la mise en oeuvre du procede
US4743558A (en) * 1984-10-26 1988-05-10 Jean Guigan Method of performing medical analysis on a sample of liquid by means of at least one liquid reagent, and apparatus for performing the method
US6095202A (en) * 1998-04-15 2000-08-01 Research Foundation State University Of New York Method and device for packing capillary columns
US20020141900A1 (en) * 1998-06-09 2002-10-03 Shenheng Guan Apparatus for screening catalysts in a parallel fixed-bed reactor
US6623968B1 (en) 1996-02-28 2003-09-23 University Of Houston Parallel flow reactor and apparatus for testing catalysts
WO2005059085A3 (en) * 2003-12-15 2005-08-04 Commissariat Energie Atomique Method and device for division of a biological sample by magnetic effect
WO2008138145A1 (en) * 2007-05-16 2008-11-20 2138357 Ontario Inc. Centripetal container processing apparatus
US20160354774A1 (en) * 2015-06-07 2016-12-08 Delta Electronics, Inc. Centrifugal flow channel device and centrifugal flow channel body
WO2018055432A1 (en) * 2016-09-20 2018-03-29 Foss Analytical A/S Filtration device, a filtration system and a method of using the same

Families Citing this family (4)

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Publication number Priority date Publication date Assignee Title
IT1097442B (it) * 1977-08-18 1985-08-31 Guigan Jean Dispositivo di condizionamento di un campione di liquido in preparazione della sua analisi
US4985143A (en) * 1988-06-06 1991-01-15 The University Of Maryland Method for packing chromatographic beds
DE20210239U1 (de) 2002-07-03 2003-11-13 Robert Bosch Gmbh, 70469 Stuttgart Dosiereinheit für flüssige Pharmazeutika
JP6349721B2 (ja) * 2013-12-24 2018-07-04 凸版印刷株式会社 試料分析チップ

Citations (1)

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Publication number Priority date Publication date Assignee Title
US3683973A (en) * 1970-10-13 1972-08-15 Donald W Hatcher Sr Rotor system and method for manipulating liquid matter

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3683973A (en) * 1970-10-13 1972-08-15 Donald W Hatcher Sr Rotor system and method for manipulating liquid matter

Cited By (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3870014A (en) * 1973-05-24 1975-03-11 Corning Glass Works Liquid and aerosol collecting device
US3986534A (en) * 1974-07-30 1976-10-19 Intertechnique S.A. Device for measuring and dispensing fractionary volumes of liquid samples
US4154793A (en) * 1977-08-18 1979-05-15 Jean Guigan Device for conditioning a sample of liquid for analyzing
US4323364A (en) * 1979-10-31 1982-04-06 Michael Scherz Method of and apparatus for examining substances and mixtures of substances
FR2522812A1 (fr) * 1982-03-05 1983-09-09 Guigan Jean Procede pour delivrer de tres faibles doses a partir d'un echantillon liquide et dispositif pour la mise en oeuvre du procede
US4743558A (en) * 1984-10-26 1988-05-10 Jean Guigan Method of performing medical analysis on a sample of liquid by means of at least one liquid reagent, and apparatus for performing the method
US6623968B1 (en) 1996-02-28 2003-09-23 University Of Houston Parallel flow reactor and apparatus for testing catalysts
US6095202A (en) * 1998-04-15 2000-08-01 Research Foundation State University Of New York Method and device for packing capillary columns
US20020141900A1 (en) * 1998-06-09 2002-10-03 Shenheng Guan Apparatus for screening catalysts in a parallel fixed-bed reactor
US7241424B2 (en) 1998-06-09 2007-07-10 Symyx Technologies, Inc. Apparatus for screening catalysts in a parallel fixed-bed reactor
WO2005059085A3 (en) * 2003-12-15 2005-08-04 Commissariat Energie Atomique Method and device for division of a biological sample by magnetic effect
US20070199901A1 (en) * 2003-12-15 2007-08-30 Commissariat A L'energie Atomique Method And Device For Division Of A Biological Sample By Magnetic Effect
US8673153B2 (en) 2003-12-15 2014-03-18 Commissariat A L'energie Atomique Method and device for division of a biological sample by magnetic effect
WO2008138145A1 (en) * 2007-05-16 2008-11-20 2138357 Ontario Inc. Centripetal container processing apparatus
US20100147415A1 (en) * 2007-05-16 2010-06-17 2138357 Ontario Inc. Centripetal container processing apparatus
US20160354774A1 (en) * 2015-06-07 2016-12-08 Delta Electronics, Inc. Centrifugal flow channel device and centrifugal flow channel body
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Also Published As

Publication number Publication date
SE384271B (sv) 1976-04-26
NL7200160A (ja) 1972-07-11
NL164133C (nl) 1980-11-17
DE2200730C3 (de) 1978-06-22
GB1330994A (en) 1973-09-19
DE2200730B2 (de) 1977-11-03
DE2200730A1 (de) 1972-07-27
CA960193A (en) 1974-12-31
JPS5232272B1 (ja) 1977-08-20

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