US3759374A - Cuvette - Google Patents
Cuvette Download PDFInfo
- Publication number
- US3759374A US3759374A US00051048A US3759374DA US3759374A US 3759374 A US3759374 A US 3759374A US 00051048 A US00051048 A US 00051048A US 3759374D A US3759374D A US 3759374DA US 3759374 A US3759374 A US 3759374A
- Authority
- US
- United States
- Prior art keywords
- foil
- cuvette
- cuvettes
- sealed
- film
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Images
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/5302—Apparatus specially adapted for immunological test procedures
- G01N33/5304—Reaction vessels, e.g. agglutination plates
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/01—Arrangements or apparatus for facilitating the optical investigation
- G01N21/03—Cuvette constructions
Definitions
- the reagent solution required for a single determination can be supplied in individual small bottles which are made available to the analyst ready for use.
- the reagent mixtures can be supplied in individual, single use small bottles or plastic capsules, either by introducing the solid substances directly, or by metering the solution into the individual containers and then freeze-drying the. solution therein In the last-mentioned form, such finished reagents have found wide application.
- cuvettes which can serve both as a storage vessel for the reagent as well as a container for measuring the analysis sampleshSu ch cuvettes can be manufactured in good quality at very low prices from transparent and dimensionally stable material, especially plastics, so that it is economically feasible to use them only once.
- one-time usage offers the advantage that the cleaning and the drying (or the intermediate rinsing) of the cuvette after each measuring step arefeliminated. For these reasons, disposable single-use plastic cuvettes are presently employed in most of the discontinuousautomatic analyzers.
- the plastic cuvette In the manual technique, the plastic cuvette has not received widespread acceptance heretofore, especially those which are adapted to serve both as the storage container for the reagents for a single determination and for the optical measurement or the visual evaluation of the analytical sample. The reason apparently is v the lack of a simple closure device. Because of the measuring techniques employed, rectangular or square internal cross sections or basal surfaces arepreferred.
- the aperture cross section must not be smaller than the internal cross section, so that the inner surfaces of the cuvette form a truncated pyramid with an inclination of the side wall of -5. Consequently, rectangular or square apertures are produced which are difficult to seal.
- glue to the normal square opening of the cuvette ahead portion of plastic having device.
- thesealing of filled cuvette s having a rectangular or square aperture is accomplished in a simple and inexpensive manner by bonding, e.g., gluing, welding or sealing a film or foil to the upper edges of the side walls defining the aperture.
- FIG. 1 is a perspective invention
- FIG. 2 is a side elevation of a plurality of cuvettes of this invention joined together by the sealing means;*and FIG. 3'is a perspective view of a plurality of cuvettes shown'in FIG. 2 joined by a common sealing means.
- each of the four side walls 2 of cuvette 10 have a recessed portion 4 of reduced thickness extending to the upper edge of the side wall and forming a shoulder in the outer surface of the side wall.
- the indented portions 4 and shoulders 5 of adjacent cuvettes and the portion of the film or foil 3a above form a cavity 6 which facilitates separating the cuvettes by cutting the film or foil with a knife, pencil or other sharp or pointed utensil. Cutting of the common web 3a can be facilitated by optional score or printed guidelines 7.
- the upper surface of the film or foil 3a is printed with indicia identifying the contents of the cuvette.
- the cuvettes of this invention can be formed of glass, quartz, or, preferably, plastic and are transparent, at least in the zone of the beam path, in the wavelength range to be measured, e.g., 200-800 nanometersor a partial range thereof.
- Preferred materials are plastics which can be formed into cuvettes by injection molding, for example, polystyrene or polymethacrylates and, in particular, polymethacrylates formed from lower-alkyl methacrylates, e.g., polymethyl, ethyl, propyl, isopropyl, n-butyl or tert.-butyl methacrylate, or mixed polymeric esters of methacrylic acid with various, especially lower, alcohols.
- Polymethyl methacrylate and polyethyl methacrylate are especially suitable, since they have good transmissibility in the ultraviolet range and thus permit measurements in the UV range without large loss of energy.
- the novel cuvette can also be formed from cellulose esters, such as for example, cellulose or butyrate, or mixed esters of cellulose with various, especially lower, carboxylic acids, especially cellulose acetates/butyrates, for example, those sold under the tradename Acetobutyrat.
- cellulose esters such as for example, cellulose or butyrate, or mixed esters of cellulose with various, especially lower, carboxylic acids, especially cellulose acetates/butyrates, for example, those sold under the tradename Acetobutyrat.
- ionic carboxylgroup-containing ethylene copolymers which can optionally be cross-linked, for example, polymers of ethylene and other unsaturated monomers, e.g., acrylic acid derivatives, especially those polymers sold under the trademark Surlyn A.”
- Polymeric carbonic acid esters of aromatic bisphenols e.g., those sold under the trademark Makrolon, can also be used.
- the plan form of the cuvette i.e., its base cross section and aperture, is preferably square with an optical path length inner edge length of the plan form) of 10 mm.
- the cuvette preferably has a height of 30-60 mm.
- the outer walls of the cuvette are preferably plane-parallel. However, they can also beformed into other shapes suitable for optical measurement. For example, the outer surfaces of the side walls can form an angle with the vertical, for instance of the same order of magnitude as the inner surfaces thereof.
- the wall thickness of the cuvette is preferably 0.3 10 mm., especially l 5 mm.
- the dimensions of the square or rectangular aperture preferably corresponds to the entire inner cross section of the cuvette.
- a metal or metal alloy foil preferably aluminum, or film (plastic or paper) can be employed.
- the foil or film can be rigid, self-supporting or non-self-supporting and can be of a thickness of 5 1,000 n, preferably 20-50 lb.
- Laminated foils and films (which term includes sheets of paper) can also be em- 4 ployed. If the film or foil is not self-bonding, it can be provided with a layer of adhesive on one face thereof, preferably adhesives of the hot glue type which, at
- Suitable foils provided with a layer of hot glue are commercially available.
- Especially tight bonds between aluminum foils and polymethacrylate cuvettes are obtained, for example, by applying the commercial adhesive V 274/6 (producer: Ardal-Klebstoffwerke, Mainz) to the foil, either in a molten condition or dissolved in a solvent.
- V 274/6 producer: Ardal-Klebstoffwerke, Mainz
- a uniform layer can be obtained by spreading the solution, applying it by a roller, or, best of all, by spraying. Thereafter, the solvent is allowed to evaporate, optionally at a higher temperature.
- the opposite face of the foils can be subjected to a continuous printing process in accordance with the conventional methods, suitably in such a manner that, later on, each cuvette seal bears at least once the text describing the contents. It is also possible to apply the layer of adhesive to the upper edge of the sides of the cuvette which define the aperture, rather than to the foil, or to both.
- the adhesive can be omitted.
- the cuvette can be sealed by placing the surface of the film or foil coated with the adhesive layer in contact with the upper edges of the side walls 2 of the cuvette 10 and pressing it into place with a planar plate.
- a hot glue is employed, the plate is heated to the temperature required to soften the glue, e.g., C.
- a normal household iron can be used as the heated plate.
- the sealing step is conducted analogously to the sealing of a single cuvette, viz., with a heatable metallic plate.
- they are preferably disposed on a planar surface.
- the cuvette is first provided with a temporary seal.
- a temporary seal is of interest when the reagent in the cuvette is to be freeze-dried and must be sealed, for preservation reasons, under a nitrogen atmosphere in the lyophilizing chamber.
- the film or foil can be attached to the plates disposed above the plates supporting the. cuvettes.
- dry nitrogen is introduced into the chamber. Due to the sealing hydraulics, with the chamber closed, the foil is pressed so firmly against the cuvettes that a temporary seal is obtained.
- the permanent or final seal is achieved with the aid of a heated metal plate in the manner described above after the chamber has been'opened.
- the cuvette seals produced in this manner provide a very good seal. They can withstand an internal pressure of about 2 atmospheres gauge or more. Yet, later on, the'sealing foil or film can very easily be removed during use by tearing off the film or foil. Alternatively, it is also possible to simply penetrate the foil, to put the cuvette to use, using the tip of the measuring pippette used to introduce the liquid sample into the cuvette.
- the cuvettes are expediently provided on the outer upper edge, with a recessed portion 4 which acts as a guide for a blade during the cutting process which separates the cuvettes joined by a common film or foil 3a.
- the shoulder 5 advantageously has a width of about 0.2 1 mm. and the recessed portion 4 has a height of about 0.2 mm.
- the width of this recessed portion-must be dimensioned so that the upper edges of the side walls 2 defining the aperture of the cuvette have a minimum thickness of about 0.2 mm, and preferably thickness of 0.8 1.2 mm. It is, of course, also possible to employ cuvettes having, in place of a recessed outer face, an outwardly beveled or an outwardly rounded upper edge to provide the cavity which guides the'cutting means.
- Potassium phosphate monobasic; potassium phosphate, dibasic; DL-alanine; NADH,; and lactate dehydrogenase (for determining glutamatepyruvate transaminase); and t I c. Potassium phosphate, monobasic; potassium phosphate, dibasic; sodium-L-asparaginate; NADH,; and malate dehydrogenase (for the determination of glutamate-oxalacetate transaminase).
- the novel cuvette can be provided with a partition separating the lower portion of the cuvette into two chambers.
- the mutually incompatible auxiliary substances can be introduced in metered quantities into these chambers, e.g., in the form of solutions, with subsequent freeze-drying.
- the reactants can be combined by shaking.
- the cuvettes, or bundles of cuvettes are preferably packed into a metal container or in a metallic foil, op-. tionally in the form of packaged bundles, optionally with the addition of a drying agent.
- a second, uncoated aluminum foil is placed thereover. Then, pressure and heat are applied to the upper face of the foil for about 15 seconds with a household iron adjusted to 150 C. (wool). Thereafter, the foil is cut in the channels formed by the indented portion (grooves) of the cuvettes with a nife.
- EXAMPLE 2 One kg. of Ardal V274/6 contact cement is melted and mixed with ml. of chloroform. The solution is introduced into a foil spreading machine wherein the solution runs, without the use of rolls, directly onto the aluminum foil disposed underneath the storage tank.
- the foil moves at a speed of cm./min. beneath the applicator blade, and is coated during this procedure with a thin film of adhesive. After passing a drying channel and cooling, the foil is again reeled up on a drum, suitably with the interposition of a separating paper (e.g., siliconized paper), to prevent the foil from sticking together.
- a separating paper e.g., siliconized paper
- the cuvettes are sealed as described in Examples 1(b) and 1(c).
- a device having four temperature-controllable plates.
- the uppermost plate serves as radiation protection, and the lower three plates serve as supporting plates.
- the arrangement also contains a hydraulic unit with which the plates can later be pressed together.
- the adhesive coated aluminum foil produced as described in Example 2, is attached to the undersides of the upper three plates so that the printed side is oriented upwardly and the side having the coating of hot glue is directed downwardly.
- the three frames with the filled cuvettes are placed on the three lower plates, and a freeze-drying process is conducted in a conventional manner. After introducing a nitrogen atmosphere, but before opening the chamber, the plates and thus also the cuvettes positioned between the plates and the foil, are pressed one to the other with the aid of the hydrau-- lic unit for a short period of time. When the frames with the cuvettes are withdrawn from the chamber, the foil adheres to the cuvettes so tightly that the nitrogen cannot escape. Thereafter, a plate heated to 150 C.
- the foil between the cuvettes is cut by guiding ablade along in the channels formed by the indented upper portion 4 of adjacent cuvettes. Not all of the cuvettes are separated from one another. Instead, the foil is cut so as to leave, e.g., 25 cuvettes together in a bundle. -After releasing the setscrews, the bundles of cuvettes, filled with reagent, sealed, and labeled, can be withdrawn from the frame and further packaged.
- a single cuvette is separated from the bundle, simultaneously removing the foil closure.
- Two ml. of water and 0.5 ml. of the serum to be examined are added thereto, the components are mixed, and the reduction of extinction (A E per minute) is measured at 366 nanometers (1 cm. layer thickness).
- GOT concentration is calculated in accordance with the following-formula:
- the solution contains 2 X 10 M of NADH in 0.02 M of bicarbonate buffer, pH 9.5.
- the freeze-dried product is dissolved in a 6 X 10" M of pyruvate solution in 0.l M of phosphate buffer, pH 7.4, rather than in water.
- EXAMPLE 4 A commercial hot melt film (silicon paper with a coating of hot glue) is pressed, with the aid of an iron, heated roll or other suitable heated device, for a few seconds onto printed paper at about C. After cooling, the silicon paper can be readily pulled from the printed paper, to which the hot glue adheres completely.
- the printed paper, provided with a layer of this hot glue, is employed for sealing the cuvettes in accordance with Examples 1(b) and 1(0).
- a sealed cuvette having a rectangular or square basal surface and side walls whose inner surfaces form a truncated pyramid having a side wall inclination of 0-5 and whose upper edges form a rectangular or square apparatusure corresponding in dimensions to the inner cross section of the cuvette and whose side walls have a recessed outer face at their upper end which forms a shoulder in said side walls extending to their upper edge, formed of a transparent and dimensionally stable plastic which is light-permeable in at least a portion of the wavelength range from 200-800 nanometers and adapted for string solids and liquids and for the optical measurement of analytical samples, said aperture being sealed by a foil or film bonded to said upper edge of said side walls.
- a cuvette according toclaim 1 formed of polystyrene.
- a cuvette according to claim 1 whose aperture is sealed with aluminum foil.
- a cuvette according to claim 5 whose aperture is sealed with aluminum foil.
- a plurality of cuvettes according to claim 1 whose film bears identifying indicia on its outer surface. side walls are in face-to-face contact and which are 9.
- a cuvette according to claim 2 whose aperture is joined together by the film or foil sealing their aperture. sealed with aluminum foil.
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- Health & Medical Sciences (AREA)
- Immunology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- General Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Pathology (AREA)
- Urology & Nephrology (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Optical Measuring Cells (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
- Devices For Use In Laboratory Experiments (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19691933689 DE1933689A1 (de) | 1969-07-03 | 1969-07-03 | Kuevette |
Publications (1)
Publication Number | Publication Date |
---|---|
US3759374A true US3759374A (en) | 1973-09-18 |
Family
ID=5738714
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US00051048A Expired - Lifetime US3759374A (en) | 1969-07-03 | 1970-06-30 | Cuvette |
Country Status (11)
Country | Link |
---|---|
US (1) | US3759374A (fr) |
JP (1) | JPS5015598B1 (fr) |
BE (1) | BE752777A (fr) |
CH (1) | CH512934A (fr) |
CS (1) | CS164269B2 (fr) |
DE (1) | DE1933689A1 (fr) |
FR (1) | FR2050482B1 (fr) |
GB (1) | GB1259059A (fr) |
IL (1) | IL34427A (fr) |
NL (1) | NL7006315A (fr) |
SE (1) | SE377499B (fr) |
Cited By (33)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3968876A (en) * | 1975-03-19 | 1976-07-13 | Brookfield Richard A | Sealed container with a sterilized hypodermic needle within it and method for effecting the sealing thereof |
DE2711853A1 (de) * | 1977-03-18 | 1978-09-21 | Eppendorf Geraetebau Netheler | Gefaessverbund mit einer mehrzahl von kuevetten oder reaktionsgefaessen und haltevorrichtung fuer einen solchen verbund |
US4154795A (en) * | 1976-07-23 | 1979-05-15 | Dynatech Holdings Limited | Microtest plates |
US4198484A (en) * | 1978-07-26 | 1980-04-15 | Abbott Laboratories | Cuvette ampule for use with automatic analyzer apparatus |
USRE30391E (en) * | 1976-02-23 | 1980-09-02 | Abbott Laboratories | Chemical analysis cuvette |
US4249826A (en) * | 1977-07-25 | 1981-02-10 | Laboratoires Biotrol S.A. | Method and device for analyzing and measuring out constituents of solid or liquid media |
US4251159A (en) * | 1979-01-15 | 1981-02-17 | American Hospital Supply Corporation | Disposable multi-chamber cuvette |
US4472357A (en) * | 1981-11-18 | 1984-09-18 | Medical Laboratory Automation, Inc. | Blood bank cuvette cassette and label therefor |
US4751186A (en) * | 1984-02-15 | 1988-06-14 | Eppendorf Geratebau Netheler & Hinz Gmbh | Process for performing sample analyses and rack for performing the process |
USRE34133E (en) * | 1976-07-23 | 1992-11-24 | Dynatech Holdings, Ltd. | Microtest plates |
DE4217868A1 (de) * | 1992-05-29 | 1993-12-02 | Univ Schiller Jena | Temperierbare Multiküvette |
US5401465A (en) * | 1992-05-05 | 1995-03-28 | Chiron Corporation | Luminometer with reduced sample crosstalk |
DE4405375A1 (de) * | 1994-02-19 | 1995-08-24 | Fritz Nerbe Nachfolger Juergen | Mikrotiterplatte |
US5514343A (en) * | 1994-06-22 | 1996-05-07 | Nunc, As | Microtitration system |
US5720924A (en) * | 1993-04-23 | 1998-02-24 | Boehringer Mannheim Gmbh | Storage system for test elements |
EP0843171A2 (fr) * | 1996-11-14 | 1998-05-20 | KONE Instruments Oy | Paquet de cuvettes multiples, méthode et dispositif pour charger les cuvettes dans un appareil de mesure |
DE19736630A1 (de) * | 1997-08-22 | 1999-03-11 | Schott Glas | Mikrotiterplatte |
US6333008B1 (en) * | 1994-08-17 | 2001-12-25 | Stratec Eletronik Gnbh | Measuring system and method for performing luminometric series analyses as well as multiple cuvette for receiving liquid samples therefor |
US20020009397A1 (en) * | 2000-06-06 | 2002-01-24 | Taisuke Hirono | Cuvette stand and stand with cuvettes |
EP1234614A1 (fr) * | 2001-02-27 | 2002-08-28 | Pentapharm Gmbh | Récipient-doseur subdivisé par des nervures pour la réception des réagents, sa fabrication et son usage |
US20040226984A1 (en) * | 2003-05-13 | 2004-11-18 | Smith Philip Russel James | Tube for storing fluid |
US20050019231A1 (en) * | 2001-09-28 | 2005-01-27 | Kahl Johan Valentin | Flow chamber |
US20050079622A1 (en) * | 2003-10-14 | 2005-04-14 | Davis Freeman | Packaging of multiple fluid receptacles |
EP1524036A2 (fr) * | 2003-10-14 | 2005-04-20 | Ortho-Clinical Diagnostics, Inc. | Emballage pour une pluralite de receptacles de liquide |
EP1550853A1 (fr) * | 2002-07-25 | 2005-07-06 | Nippon Sheet Glass Co.,Ltd. | Recipient biochimique |
US20110064543A1 (en) * | 2008-05-28 | 2011-03-17 | Thermo Fisher Scientific Oy | Reaction vessel and method for the handling thereof |
US20120292220A1 (en) * | 2010-02-26 | 2012-11-22 | Vesa Nuotio | Handling package of cuvettes |
USD766760S1 (en) * | 2014-03-19 | 2016-09-20 | Sony Corporation | Container for measuring electrical characteristics |
USD810959S1 (en) * | 2015-09-29 | 2018-02-20 | Bd Kiestra B.V. | Cuvette tray |
US20180224460A1 (en) * | 2017-02-08 | 2018-08-09 | Becton, Dickinson And Company | Dried dye reagent devices and methods for making and using the same |
USD839448S1 (en) | 2015-09-29 | 2019-01-29 | Bd Kiestra B.V. | Cuvette |
US11099121B2 (en) * | 2019-02-05 | 2021-08-24 | BacterioScan Inc. | Cuvette device for determining antibacterial susceptibility |
US11833005B2 (en) * | 2019-07-22 | 2023-12-05 | Ivoclar Vivadent Ag | Container for producing a dental synthetic material composition |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CH615755A5 (fr) * | 1976-06-09 | 1980-02-15 | Electro Nucleonics | |
IT1115523B (it) * | 1977-05-09 | 1986-02-03 | Sclavo Inst Sieroterapeut | Apparecchiatura adatta all'analisi di componenti di fluidi |
DE3024835A1 (de) * | 1980-07-01 | 1982-01-28 | Bayer Ag, 5090 Leverkusen | Reagenz fuer die haemoglobinbestimmung |
FR2570189B1 (fr) * | 1984-09-13 | 1986-09-26 | Immunotech Sa | Procede de dosage immunoenzymologique et moyens pour sa mise en oeuvre |
Citations (10)
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US2018005A (en) * | 1933-11-17 | 1935-10-22 | Owens Illinois Glass Co | Sealing means for empty containers |
US2138241A (en) * | 1935-08-09 | 1938-11-29 | Koch Herman | Sealed package |
US2258073A (en) * | 1939-01-12 | 1941-10-07 | Daniel S Stevens | Disposable colorimeter cell |
US2549574A (en) * | 1948-07-08 | 1951-04-17 | Archer Daniels Midland Co | Apparatus for making fluorophotometric measurements |
US2783908A (en) * | 1953-02-13 | 1957-03-05 | Glaxo Lab Ltd | Closures for bottles, vials and the like |
US2949710A (en) * | 1958-09-16 | 1960-08-23 | Airkem Inc | Gel packaging method and resulting package |
GB1004176A (en) * | 1962-11-29 | 1965-09-08 | Unilever Ltd | Packaging containers |
US3503493A (en) * | 1968-01-08 | 1970-03-31 | Hoffmann La Roche | Medicament packaging device |
US3579306A (en) * | 1969-01-22 | 1971-05-18 | Organon | Diagnostic test device |
US3673302A (en) * | 1967-01-09 | 1972-06-27 | Globe Union Inc | Method for fabricating battery cases |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR1151435A (fr) * | 1956-06-14 | 1958-01-30 | Bret Oil | Bidon pour huile de graissage |
FR1538610A (fr) * | 1967-07-27 | 1968-09-06 | Dispositif de gaufrage d'une bande complexe destinée à l'obturation de récipients de produits divers |
-
1969
- 1969-07-03 DE DE19691933689 patent/DE1933689A1/de active Pending
-
1970
- 1970-03-26 CH CH459270A patent/CH512934A/de not_active IP Right Cessation
- 1970-04-29 NL NL7006315A patent/NL7006315A/xx unknown
- 1970-04-30 IL IL34427A patent/IL34427A/en unknown
- 1970-05-18 GB GB1259059D patent/GB1259059A/en not_active Expired
- 1970-05-22 CS CS3607A patent/CS164269B2/cs unknown
- 1970-06-30 US US00051048A patent/US3759374A/en not_active Expired - Lifetime
- 1970-06-30 BE BE752777D patent/BE752777A/fr unknown
- 1970-07-02 SE SE7009190A patent/SE377499B/xx unknown
- 1970-07-03 FR FR7024739A patent/FR2050482B1/fr not_active Expired
- 1970-07-03 JP JP45057815A patent/JPS5015598B1/ja active Pending
Patent Citations (10)
Publication number | Priority date | Publication date | Assignee | Title |
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US2018005A (en) * | 1933-11-17 | 1935-10-22 | Owens Illinois Glass Co | Sealing means for empty containers |
US2138241A (en) * | 1935-08-09 | 1938-11-29 | Koch Herman | Sealed package |
US2258073A (en) * | 1939-01-12 | 1941-10-07 | Daniel S Stevens | Disposable colorimeter cell |
US2549574A (en) * | 1948-07-08 | 1951-04-17 | Archer Daniels Midland Co | Apparatus for making fluorophotometric measurements |
US2783908A (en) * | 1953-02-13 | 1957-03-05 | Glaxo Lab Ltd | Closures for bottles, vials and the like |
US2949710A (en) * | 1958-09-16 | 1960-08-23 | Airkem Inc | Gel packaging method and resulting package |
GB1004176A (en) * | 1962-11-29 | 1965-09-08 | Unilever Ltd | Packaging containers |
US3673302A (en) * | 1967-01-09 | 1972-06-27 | Globe Union Inc | Method for fabricating battery cases |
US3503493A (en) * | 1968-01-08 | 1970-03-31 | Hoffmann La Roche | Medicament packaging device |
US3579306A (en) * | 1969-01-22 | 1971-05-18 | Organon | Diagnostic test device |
Cited By (51)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3968876A (en) * | 1975-03-19 | 1976-07-13 | Brookfield Richard A | Sealed container with a sterilized hypodermic needle within it and method for effecting the sealing thereof |
USRE30391E (en) * | 1976-02-23 | 1980-09-02 | Abbott Laboratories | Chemical analysis cuvette |
US4154795A (en) * | 1976-07-23 | 1979-05-15 | Dynatech Holdings Limited | Microtest plates |
USRE34133E (en) * | 1976-07-23 | 1992-11-24 | Dynatech Holdings, Ltd. | Microtest plates |
DE2711853A1 (de) * | 1977-03-18 | 1978-09-21 | Eppendorf Geraetebau Netheler | Gefaessverbund mit einer mehrzahl von kuevetten oder reaktionsgefaessen und haltevorrichtung fuer einen solchen verbund |
US4249826A (en) * | 1977-07-25 | 1981-02-10 | Laboratoires Biotrol S.A. | Method and device for analyzing and measuring out constituents of solid or liquid media |
US4198484A (en) * | 1978-07-26 | 1980-04-15 | Abbott Laboratories | Cuvette ampule for use with automatic analyzer apparatus |
US4251159A (en) * | 1979-01-15 | 1981-02-17 | American Hospital Supply Corporation | Disposable multi-chamber cuvette |
US4472357A (en) * | 1981-11-18 | 1984-09-18 | Medical Laboratory Automation, Inc. | Blood bank cuvette cassette and label therefor |
US4751186A (en) * | 1984-02-15 | 1988-06-14 | Eppendorf Geratebau Netheler & Hinz Gmbh | Process for performing sample analyses and rack for performing the process |
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Also Published As
Publication number | Publication date |
---|---|
FR2050482B1 (fr) | 1975-01-10 |
DE1933689A1 (de) | 1971-01-21 |
CH512934A (de) | 1971-09-30 |
IL34427A0 (en) | 1970-06-17 |
BE752777A (fr) | 1970-12-30 |
JPS5015598B1 (fr) | 1975-06-06 |
SE377499B (fr) | 1975-07-07 |
NL7006315A (fr) | 1971-01-05 |
IL34427A (en) | 1973-10-25 |
FR2050482A1 (fr) | 1971-04-02 |
CS164269B2 (fr) | 1975-11-07 |
GB1259059A (fr) | 1972-01-05 |
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