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Sequentially dispensing syringe with multiple needle assembly

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US3749084A
US3749084A US3749084DA US3749084A US 3749084 A US3749084 A US 3749084A US 3749084D A US3749084D A US 3749084DA US 3749084 A US3749084 A US 3749084A
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assembly
fluid
dispensing
means
member
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A Cucchiara
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A Cucchiara
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Detecting, measuring or recording for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/150007Details
    • A61B5/150015Source of blood
    • A61B5/15003Source of blood for venous or arterial blood
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Detecting, measuring or recording for diagnostic purposes; Identification of persons
    • A61B5/02Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
    • A61B5/026Measuring blood flow
    • A61B5/0275Measuring blood flow using tracers, e.g. dye dilution
    • A61B5/02755Radioactive tracers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Detecting, measuring or recording for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/150007Details
    • A61B5/150206Construction or design features not otherwise provided for; manufacturing or production; packages; sterilisation of piercing element, piercing device or sampling device
    • A61B5/150236Pistons, i.e. cylindrical bodies that sit inside the syringe barrel, typically with an air tight seal, and slide in the barrel to create a vacuum or to expel blood
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61B5/150007Details
    • A61B5/150206Construction or design features not otherwise provided for; manufacturing or production; packages; sterilisation of piercing element, piercing device or sampling device
    • A61B5/150244Rods for actuating or driving the piston, i.e. the cylindrical body that sits inside the syringe barrel, typically with an air tight seal, and slides in the barrel to create a vacuum or to expel blood
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61B5/150007Details
    • A61B5/150206Construction or design features not otherwise provided for; manufacturing or production; packages; sterilisation of piercing element, piercing device or sampling device
    • A61B5/150251Collection chamber divided into at least two compartments, e.g. for division of samples
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61B5/150206Construction or design features not otherwise provided for; manufacturing or production; packages; sterilisation of piercing element, piercing device or sampling device
    • A61B5/150259Improved gripping, e.g. with high friction pattern or projections on the housing surface or an ergonometric shape
    • AHUMAN NECESSITIES
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    • A61B5/150206Construction or design features not otherwise provided for; manufacturing or production; packages; sterilisation of piercing element, piercing device or sampling device
    • A61B5/150267Modular design or construction, i.e. subunits are assembled separately before being joined together or the device comprises interchangeable or detachable modules
    • AHUMAN NECESSITIES
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    • A61B5/150374Details of piercing elements or protective means for preventing accidental injuries by such piercing elements
    • A61B5/150381Design of piercing elements
    • A61B5/150389Hollow piercing elements, e.g. canulas, needles, for piercing the skin
    • A61B5/150404Specific design of proximal end
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    • A61B5/150381Design of piercing elements
    • A61B5/150503Single-ended needles
    • A61B5/150519Details of construction of hub, i.e. element used to attach the single-ended needle to a piercing device or sampling device
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    • A61B5/150732Needle holders, for instance for holding the needle by the hub, used for example with double-ended needle and pre-evacuated tube
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    • A61B5/150755Blood sample preparation for further analysis, e.g. by separating blood components or by mixing
    • AHUMAN NECESSITIES
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    • A61B5/153Devices specially adapted for taking samples of venous or arterial blood, e.g. with syringes
    • A61B5/1535Devices specially adapted for taking samples of venous or arterial blood, e.g. with syringes comprising means for indicating vein or arterial entry
    • AHUMAN NECESSITIES
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    • AHUMAN NECESSITIES
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    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/1785Syringes comprising radioactive shield means
    • AHUMAN NECESSITIES
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    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/19Syringes having more than one chamber, e.g. including a manifold coupling two parallelly aligned syringes through separate channels to a common discharge assembly
    • AHUMAN NECESSITIES
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    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/315Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31596Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms comprising means for injection of two or more media, e.g. by mixing
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/32Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M2005/1787Syringes for sequential delivery of fluids, e.g. first medicament and then flushing liquid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/315Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31596Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms comprising means for injection of two or more media, e.g. by mixing
    • A61M2005/31598Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms comprising means for injection of two or more media, e.g. by mixing having multiple telescopically sliding coaxial pistons encompassing volumes for components to be mixed
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/32Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A61M2005/3201Coaxially assembled needle cannulas placed on top of another, e.g. needles having different diameters

Abstract

This invention relates to a syringe having two or more dispensing chambers therewithin operable to dispense from or fill independent chambers in any desired sequential order. More specifically, this invention relates to a syringe having a multiple needle assembly connected to a main housing and having an inner dispensing and outer dispensing assemblies operable to independently either dispense or receive fluids, such may be operable to inject fluids into the blood system at variable steps thereon which process is most desirable when utilizing radioactive fluids for medical analysis.

Description

Ulliifid States Patent 1 [111 3,749,084 Cucchiara July 31, 1973 [5 SEQUENTIALLY DISPENSING SYRINGE 3,437,242 4/1969 Poitras 222/386 X WITH MULTIPLE NEEDLE ASSEMBLY 128/218 M, 220, 215, 216, 218 P, 218 PA, 218 N, 218 NV, 218 C, 218 A, 218 D, 218 DA, 218 F, 218 G, 221, 234, 235; 222/386, 135

References Cited UNITED STATES PATENTS FOREIGN PATENTS OR APPLICATIONS Primary Examiner-Richard A. Gaudet Assistant Examiner-J. C. McGowan Atl0rneyPhillip A. Rein [5 7] ABSTRACT This invention relates to a syringe having two or more dispensing chambers therewithin operable to dispense from or fill independent chambers in any desired sequential order. More specifically, this invention relates to a syringe having a multiple needle assembly connected to a main housing and having an inner dispensing and outer dispensing assemblies operable to indefig i' at i 2: pendently either dispense or receive fluids, such may Francis '128/221 be operable to inject fluids into the blood system at H il 123 213 C variable steps thereon which process is most desirable Albisser 123/2 F when utilizing radio-active fluids for medical analysis. H 128 214 R sri yderw. 11 28/220 6 Claims 7 Drawing '2" PATENIE JUL 31 I973 'SHEEI 2 BF 3 m m 3 2 6 g J l I I I II/ I I r/ m Fig. 5

INVENTOE ALFRED L. CUCCHIARA INVENTOP ALFRED L.CUCCHIAQA ATTOQNEY SHEEI 3 OF 3 PATENIELJULG 1 ms SEQUENTIALLY DISPENSING SYRINGE WITH MULTIPLE NEEDLE ASSEMBLY Numerous types of syringe structures are available in the prior art operable to receive a powder and a liquid thereon and then mix the same by actuation of plunger assemblies. However, none of the prior art devices are operable through interconnection of syringe structures so as to independently and selectively dispense fluids into a person thereby requiring only one needle puncture. Additionally, none of the syringe structures of the prior art are operable to dispense multiple fluids through independent needle channels to prevent and not achieve a mixing of the fluids dispensed. Additionally, the prior art structures are not operable in referse to receive independent blood samples from the patient to be used for various testing purposes thus achieving the same with only one puncture of the patients arm which is desirable.

In preferred embodiments of this invention includes a syringe means having a couple of embodiments being 1) an independent dual syringe structure; and 2) an independent plurality syringe structure. The independent dual syringe structure includes a main housing means having a needle assembly releasably connected to one end and having within the housing means an outer dispensing assembly and an inner dispensing assembly. The housing means is provided with a cylindrical support member being tapered at one end and having an upper flange section to be grasped by ones forefingers for operation thereof. The support member has a central cavity to receive the outer dispensing assembly therewithin for dispensing of fluid through a lower end into the needle assembly. The needle assembly is provided with an inner needle member connected as by support members to an outer needle member with the outer portion adapted to fit snuggly about the lower tapered end section of the housing means. The outer dispensing assembly includes a plunger assembly having a piston head movable in contact with the inner wall of the cylindrical support member. The plunger assembly includes an elongated support body secured on the lower end to the piston head with an actuator flange on the upper end. The inner dispensing assembly includes a main plunger assembly having a piston head on one end interconnected by an elongated support member with an actuator plate at the top end thereof. The main plunger assembly is movable within an inner barrel member which is secured by support bar members to the main support member. The plunger assembly of the outer dispensing assembly and the main plunger assembly of the inner dispensing assembly are movable independently relative to the stationary housing means and barrel. member so as to independently dispense fluid through the needle assembly. In the other embodiment, the independent plurality syringe structure is somewhat identical to the other embodiment except having a triple needle assembly and having-mounted within the outer main housing means and outer dispensing assembly, an intermediate dispensing assembly, and an inner dispensing assembly. It is seen that the embodiment of the independent plurality syringe structure is operable to dispense a plurality, namely three different fluids thereby but only requiring one penetration of the patients arm for injecting fluids or receiving blood samples therefrom.

One object of this invention is to provide a new and novel syringe means to overcome the aforementioned disadvantages of the prior art devices.

One further object of this invention is to provide a syringe means including a dual syringe structure to either dispense different fluids into a patients arm, or operate by receiving a blood sample and then dispensing a fluid into a patients arm, or by dispensing a fluid into a patients arm and then receiving a blood sample, or by receiving two separate blood samples as is beneficial when clotted and unclotted samples are desired, and also during short time lapse periods when consecutive blood samples are needed over very short periods of time to determine increasing concentration of previously injected substances.

Still, one further object of this invention is provided a syringe means having a plurality of dispensing assemblies therein so as to selectively and independently dispense into and/or receive fluids from a patients arm requiring only one needle penetration which is extremely desirable.

Still, another object of this invention is to provide a new and novel syringe means having the same operable to inject a first fluid and to inject immediately afterwards a separate second fluid such that the second fluid follows the first into the blood stream which has found to be particularly beneficial for analysis of the patients blood flow in nuclear medicine.

A still further object of this invention is to provide a needle and syringe means whereas the incoming and/or outgoing fluids are kept separate while contained in and while traveling through the syringe and through the needle thereby preventing undesirable contamination of the two different fluids.

Another object of this invention is to provide a syringe means by which one plunger and barrel can be utilized to assure an intervenous puncture, which is commonly accomplished by being able to withdraw a quantity of blood, and the other plunger can therefore be depressed with the assurance of having the needle in a vein, thereby injecting a fluid into the bloodstream without coming in contact with the blood until after having left the needle, which is desirable when working with materials that must be immediately diluted with large quantities of blood and therefore preferred not to come in contact with the blood in the needle or in the syringe.

Still, one other object of this invention is to provide a new and novel syringe means which achieves a plurality of functions therewith; is accurate and novel in operation; and can achieve a purality of selective dispensing operation not shown or taught by the prior art.

Various other objects, features, and advantages of the invention will become apparent to those skilled in the art from the following discussion, taken in conjunction with the accompanying drawings, which:

FIG. 1 is a perspective view of an independent dual syringe structure of the syringe means of this invention;

FIG. 2 is a sectional view of the independent dual syringe structure taken along line 2-2 in FIG. 1;

FIG. 3, 4, and 5am schematic diagrams illustrating the use and operation of the independent dual syringe structure of this invention;

FIG. 6 is a sectional view similar to FIG. 2 illustrating another embodiment being an independent plurality syringe structure operable to dispense a plurality of fluids therefrom; and

HO. 7 is a top plan view of the independent plurality syringe structure shown in FIG. 6.

The following is a discussion and description of preferred specific embodiments of the new syringe means ofthis invention, such being made with reference to the drawings, whereupon the same reference numerals are used to indicate the same or similar parts and/or structures. It is to be understood that such discussion and description is not to unduly limit the scope ofthe inventron.

Referring to the drawings in detail and in particular to FIGS. 1 and 6, there are shown syringe means 12 consisting of two embodiments being 1) an independent dual syringe structure 14 and 2) an independent plurality syringe structure 16.

As shown in FIG. 1, the independent dual syringe structure 14 consists of a main housing means 17; a fluid directing or needle assembly 19 secured to a lower tapered end 20 of the main housing means 17; an outer dispensing assembly 21 mounted within the housing means 17; and an inner dispensing assembly 23 mounted within the outer dispensing assembly 21. The main housing means 17 consists ofa cylindrical support member 25 having the lower tapered end 20 and an upper laterally extended flange section 27. The support member 25 is provided with an inner cavity 28 to receive the outer dispensing assembly 21 snuggly therein. The upper flange section 27 is provided with outer laterally extended, downwardly curved pressure lips 31 to receive the foreflngers of one utilizing the instrument as will become obvious.

The needle assembly 19 is provided with an inner needle member 32 secured as by support elements 34 to an outer needle member 35. The inner needle member 32 is provided with an upper tapered end portion 36 and an elongated body therefrom having a lower pointed tip section 37 extended below an outer portion of the outer needle member 35. The outer needle member 35 is provided with an upper tapered end section 39 having an upper laterally extended tab 41 and tapered downwardly therefrom to a position upwardly from the lower end of the inner needle member 32 (FIG. 2). lt is noted that the needle assembly 19 can be constructed of a disposable type being readily attachable to the lower end of the tapered end section 20 of the housing means 17.

The outer or first fluid dispensing assembly 21 is provided with a plunger assembly 42 having a piston head 43 at one end interconnected by an elongated support body 45 to an upper actuator flange 47. More particularly, the piston head 43 is of a resilient sealing type material having a main body 48 tapered at both ends about a central groove 49 so as to form a positive sealing action whether extending or retracting the same. The elongated support body 45 is provided with a plurality oflongitudinally extended grooves 51 therewithin to receive support bars 53 therethrough which are connected to the inner dispensing assembly 23 as will be explained. The actuator flange 47 extends outwardly from the support body 45 so as to be readily movable in a downward manner for dispensing fluid from the chamber 28.

The inner or second fluid dispensing assembly 23 includes a main plunger assembly 54 mounted within an inner barrel member 55, the main plunger assembly 54 having a main piston head 56 on one end interconnected by a support element 58 to an actuator plate 59 on the upper end thereof. The inner barrel member 55 extends axially of the main housing means 17 and connected thereto by the support bars 53 plus connected at the lower end by vertically extended support elements 61 about its periphery so as to achieve a solid mounting to the housing means 17. The barrel member 55 has an annular laterally extended flange 62 about the upper end tapered downwardly for ease of grasping. The lower end of the barrel member 55 is of a downwardly conical shape to receive the inner needle member 32 of the needle assembly 19 therein. The main piston head 56 is constructed of a rubber type material having a tapered end section 63 so as to completely dispense on downward movement, fluid from an inner chamber 65 of the barrel member 55. Additionally, the main piston head 56 is provided with dual flange sections 66 and 67 about a main central groove 68 so as to seal with the barrel member 55 on either the extension or retraction for proper operation. The support element 58 is ofa generally X-shaped in transverse crosssection so as to reduce its weight and the upper actuator plate 59 being constructed so as to be easily moved downwardly on grasping the same with the laterally extended flange 62 of the inner barrel member 55 for dispensing fluid therefrom.

lnthe other embodiment, being the independent plurality syringe structure 16 as shown in FIG. 6, it is seen that the same includes the main housing means 17 having a needle assembly 71 connected to one end and provided internally with 1) the outer dispensing assembly 21; 2) an intermediate dispensing assembly 73; and 3) the inner dispensing assembly 23.

It is noted that the main housing means 17 is substantially identical to that previously described having the lower tapered end 21 and the upper flange section 27. The needle assembly 71 is substantially similar to the other needle assembly 19 except provided with three needle sections having the same interconnected by support elements 34 to adjacent ones and having inner sections which will fit snuggly within the independent fluid chambers so as to dispense fluid independently therefrom. it is seen that an inner needle member 74 extends below the rest with an intermediate needle member 76 next and a shorter needle member 78 is the outer needle element.

The outer dispensing assembly 21 includes the plunger assembly 42 having the piston head 43 at one end thereof secured by the support body 45 to the upper actuator flange 47. It is seen that the outer dispensing assembly 21 is substantially similar to that as shown in the first embodiment with movement downwardly dispensing fluid by use of the piston head 43 outwardly through the shorter needle member 78.

The intermediate dispensing assembly 73 is provided with a central plunger assembly 81 having a central piston head 82 therewith movable within an intermediate barrel member 84 which is secured as by support lugs 86 and vertical bars 87 to the outer housing means 17. lt is seen that the outer plunger assembly 42 has grooves on the support body 45 for movement about the support lugs 86. The intermediate dispensing assembly 73 has the piston head 82 movable by an elongated support member 89 having an actuator flange 91 on the upper end for proper dispensing therefrom.

The inner dispensing assembly 23 is substantially identical to that previously described having the main plunger assembly 54 with the main piston head 56 on one end thereof and the actuator plate 59 on the upper end. The main plunger assembly 53 is movable within the inner barrel member 55 which is a cylindrical body secured by the support lugs 86 and vertical bars 87 to the outer housing means 17.

.In the use and operation of the independent dual sy ringe structure 14 as shown in FIGS. 3, 4, and 5, the schematic diagrams are illustrated to show the device after being filled with fluids for dispensing operations. It is seen at this time that either of the fluids may be properly dispensed selectively and independently depending on the desirability of the operator and utilizing the various ones of the plunger assemblies 42 and 54. As shown in FIGS. 3 and 4, it is desired to first dispense fluid from the inner dispensing assembly having the main plunger assembly 54 moved downwardly by ones thumb against the upper actuator plate 59 with reactive force achieved by forefingers being on the flange 62. It is noted that the main piston head 56 is tapered downwardly so as to completely dispense fluid from within the barrel member 55.

Next, as shown in FIG. 5, it is seen that the outer dispensing assembly 21 can be utilized with the plunger assembly 42 moved downwardly as shown by the arrow .83 so as to move the piston head 43 downwardly within the housing means 12 to dispense the fluid therefrom. It is seen that the tapered end thereof operates to dispense same outwardly through the outer needle mem ber 35 of the needle assembly 19.

Conversely, it is obvious that from the condition in FIG. 5, the various ones of the outer dispensing assembly 21 and the inner dispensing assembly 23 can be moved upwardly so as to fill the same with blood or other samples requiring only one penetration of the patients body by the needle assembly.

In the use and operation of the independent plurality syringe structure 16, it is obvious that the same is operable as shown in FIG. 3, 4, and 5 for the dual syringe structure 73 but having one more being the intermediate dispensing assembly 73 operable to dispense therefrom selectively and independently as desired.

It is seen that the syringe means of this invention provides a new and novel structure having a plurality of dispensing assemblies movable independently and unrestrictedly to dispense from or pull in fluid thereto. It is seen that the syringe means of this invention provides a novel structure in operation not previously achieved in the prior art devices. The syringe means is particularly desirable in radio-active fields whereupon it is important to inject a first fluid into a patients arm and immediately follow the same with a second radio-active fluid and then, an additional injection of a third or the first fluid so as to enclose the radio-active fluid in a short space so that the radioactive material can be followed throughout the patients body and timed for proper examination.

While the invention has been described in conjunction with preferred specific embodiments thereof, it is to be understood that such description is tended to illustrate and not to limit the scope of the invention, which is defined in the following claims.

I claim:

1. A syringe means operable to selectively and independently dispense or receive a fluid therein, comprising:

a. a housing means having a fluid directing assembly connectable to one end thereof,

b. a first fluid dispensing assembly mounted within said housing means operably connected to'said fluid directing assembly,

c. a second fluid dispensing assembly operably connected to said first fluid dispensing assembly and said fluid directing assembly,

d. said fluid directing assembly having a first section to receive fluid from said first fluid dispensing assembly and a second section to receive fluid from said second fluid dispensing assembly,

e. said first dispensing assembly and said second fluid dispensing assembly, each operably independently to dispense from or receive in a fluid while maintaining complete separation of the fluid in the syringe means,

f. said fluid directing assembly with said first section being an elongated needle member surrounded by and connected to said second section being a second needle member, and

g. said first needle member extended beyond the outer end of said second needle member to assure proper separation of fluids utilized therein.

2. A syringe means as described in claim 1, wherein:

a. said second fluid dispensing assembly having a main plunger assembly mounted within a barrel member, said barrel member securedto said housing means, and

b. said plunger assembly having a piston head movable therein to receive in or dispense fluid from said barrel member.

3. A syringe means as described inclaim 1, including:

a. an intermediate fluid dispensing assembly mounted between said first fluid dispensing assemblysand said second fluid dispensing assembly, and

b. said fluid directing assembly being a multiple needle assembly having interconnected, first, intermediate, and second needle members to receive or inject fluid from said first, intermediate, and second fluid dispensing assemblies, respectively.

4. A syringe means operable to selectively and independently dispense or receive a fluid therein, comprising:

a. a housing means having a fluid directing assembly connectable to one end thereof,

b. a first fluid dispensing assembly mounted within said housing means operably connected to said fluid directing assembly, 1

c. a second fluid dispensing assembly operably connected to said first fluid dispensing assembly and said fluid directing assembly,

d. said fluid directing assembly having a first section to receive fluid from said first fluid dispensing assembly and a second section to receive fluid from said second fluid dispensing assembly,

e. said first fluid dispensing assembly and said second fluid dispensing assembly, each operable independentlyfto dispense from or receive in a fluid while maintaining complete separation of the fluid in the syringe means,

f. said housing means having a support member tapered at one end to receive said fluid directing assembly and having a laterally extended flange section at an upper end thereof,

g. said first fluid dispensing assembly having a plunger assembly mounted within said housing means and about said second fluid dispensing as sembly, said plunger assembly having a piston member movable longitudinally for receiving or dispensing a fluid therefrom,

. said second fluid dispensing assembly having a central barrel member secured to said housing means by bar members,

. said plunger assembly having a support body connected to said piston member, and

. said support body having a plurality of longitudinal said fluid directing assembly being a multiple needle assembly having interconnected, first, intermediate, and second needle members to receive or inject fluid from said first, intermediate. and second fluid dispensing assemblies, respectively, and

c. said intermediate fluid dispensing assembly having a piston member mounted about said barrel member and surrounded by a cylindrical casing secured to said housing means, said piston member being movable axially for fluid operation.

6. A syringe means as described in claim 5, wherein:

a. said first fluid dispensing assembly having a piston member mounted about said cylindrical casing and engagable with said housing means, and

b. said piston members having elongated slots therein to receive said bar members to permit longitudinal movement thereof.

Claims (6)

1. A syringe means operable to selectively and independently dispense or receive a fluid therein, comprising: a. a housing means having a fluid directing assembly connectable to one end thereof, b. a first fluid dispensing assembly mounted within said housing means operably connected to said fluid directing assembly, c. a second fluid dispensing assembly operably connected to said first fluid dispensing assembly and said fluid directing assembly, d. said fluid directing assembly having a first section to receive fluid from said first fluid dispensing assembly and a second section to receive fluid from said second fluid dispensing assembly, e. said first dispensing assembly and said second fluid dispensing assembly, each operably independently to dispense from or receive in a fluid while maintaining complete separation of the fluid in the syringe means, f. said fluid directing assembly with said first section being an elongated needle member surrounded by and connected to said second section being a second needle member, and g. said first needle member extended beyond the outer end of said second needle member to assure proper separation of fluids utilized therein.
2. A syringe means as described in claim 1, wherein: a. said second fluid dispensing assembly having a main plunger assembly mounted within a barrel member, said barrel member secured to said housing means, and b. said plunger assembly having a piston head movable therein to receive in or dispense fluid from said barrel member.
3. A syringe means as described in claim 1, including: a. an intermediate fluid dispensing assembly mounted between said first fluid dispensing assembly And said second fluid dispensing assembly, and b. said fluid directing assembly being a multiple needle assembly having interconnected, first, intermediate, and second needle members to receive or inject fluid from said first, intermediate, and second fluid dispensing assemblies, respectively.
4. A syringe means operable to selectively and independently dispense or receive a fluid therein, comprising: a. a housing means having a fluid directing assembly connectable to one end thereof, b. a first fluid dispensing assembly mounted within said housing means operably connected to said fluid directing assembly, c. a second fluid dispensing assembly operably connected to said first fluid dispensing assembly and said fluid directing assembly, d. said fluid directing assembly having a first section to receive fluid from said first fluid dispensing assembly and a second section to receive fluid from said second fluid dispensing assembly, e. said first fluid dispensing assembly and said second fluid dispensing assembly, each operable independently to dispense from or receive in a fluid while maintaining complete separation of the fluid in the syringe means, f. said housing means having a support member tapered at one end to receive said fluid directing assembly and having a laterally extended flange section at an upper end thereof, g. said first fluid dispensing assembly having a plunger assembly mounted within said housing means and about said second fluid dispensing assembly, said plunger assembly having a piston member movable longitudinally for receiving or dispensing a fluid therefrom, h. said second fluid dispensing assembly having a central barrel member secured to said housing means by bar members, i. said plunger assembly having a support body connected to said piston member, and j. said support body having a plurality of longitudinal grooves to receive respective ones of said bar members therein to permit axial movement of said plunger assembly.
5. A syringe means as described in claim 4, wherein: a. an intermediate fluid dispensing assembly mounted between said first fluid dispensing assembly and said second fluid dispensing assembly, b. said fluid directing assembly being a multiple needle assembly having interconnected, first, intermediate, and second needle members to receive or inject fluid from said first, intermediate, and second fluid dispensing assemblies, respectively, and c. said intermediate fluid dispensing assembly having a piston member mounted about said barrel member and surrounded by a cylindrical casing secured to said housing means, said piston member being movable axially for fluid operation.
6. A syringe means as described in claim 5, wherein: a. said first fluid dispensing assembly having a piston member mounted about said cylindrical casing and engagable with said housing means, and b. said piston members having elongated slots therein to receive said bar members to permit longitudinal movement thereof.
US3749084A 1971-05-03 1971-05-03 Sequentially dispensing syringe with multiple needle assembly Expired - Lifetime US3749084A (en)

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Cited By (77)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3985122A (en) * 1975-06-04 1976-10-12 Medical Development Corporation Multi-piston syringe device
US4188949A (en) * 1977-07-05 1980-02-19 Becton, Dickinson & Company Sequential injection syringe
US4313440A (en) * 1980-09-08 1982-02-02 Ashley Sheldon J Multipurpose double barrel syringe and method of manufacture of same
EP0076239A2 (en) * 1981-09-30 1983-04-06 Ivo Caselgrandi A syringe for use in hypodermic biopsy, featuring automatic plunger-return
US4393882A (en) * 1979-08-31 1983-07-19 American Hospital Supply Corporation Method and device for collecting, transporting, and delivering micro samples of blood
EP0104791A2 (en) * 1982-09-10 1984-04-04 Avvari Rangaswamy Analgesic syringe
US4476866A (en) * 1982-08-06 1984-10-16 Thomas J. Fogarty Combined large and small bore syringe
EP0153878A2 (en) * 1984-03-02 1985-09-04 Eolas - The Irish Science and Technology Agency An injection device
US4583978A (en) * 1983-01-23 1986-04-22 Michael Porat Syringe
US4655747A (en) * 1986-01-30 1987-04-07 Allen Jr Robert E Dual chambered syringe
FR2589738A1 (en) * 1985-11-14 1987-05-15 Lascar Marcel Syringe double room
US4929238A (en) * 1988-11-23 1990-05-29 Coeur Laboratories, Inc. Multi-pressure injector device
US4979942A (en) * 1989-10-16 1990-12-25 Johnson & Johnson Medical, Inc. Two component syringe delivery system
US5078691A (en) * 1990-03-01 1992-01-07 Hamacher Edward N Multiple-dose fluid delivery system and method
US5104375A (en) * 1989-10-16 1992-04-14 Johnson & Johnson Medical, Inc. Locking holder for a pair of syringes and method of use
US5222939A (en) * 1992-04-09 1993-06-29 Jonathan Tiefenbrun Instrument and associated method for applying biologically effective composition during surgery
WO1994007415A1 (en) * 1992-09-30 1994-04-14 Intellectual Property Investment Corporation Multichamber container for blood or other fluid samples
US5312336A (en) * 1993-04-14 1994-05-17 Habley Medical Technology Corporation Component mixing syringe
US5354285A (en) * 1991-11-29 1994-10-11 Sergej Mikhailovich Masurik Injection syringe
US5372585A (en) * 1992-04-09 1994-12-13 Tiefenbrun; Jonathan Instrument and associated method for applying biologically effective composition during laparoscopic operation
US5383906A (en) * 1993-05-12 1995-01-24 Burchett; Mark T. Nursing bottle with medication dispenser
EP0695555A1 (en) * 1992-12-01 1996-02-07 HIGASHIKAWA, Tetsuro Syringe
US5496284A (en) * 1994-09-27 1996-03-05 Waldenburg; Ottfried Dual-chamber syringe & method
US5520657A (en) * 1993-08-09 1996-05-28 Sellers; Jackie Method and device for vessel location cannulation utilizing a unique needle and syringe device
US5529189A (en) * 1995-08-02 1996-06-25 Daxor Corporation Syringe assembly for quantitative measurement of radioactive injectate and kit having same
US5630800A (en) * 1993-11-08 1997-05-20 Ferring Arzneimettel Gmbh Injection syringe for the missing and application of injection substances
DE19543240A1 (en) * 1995-11-20 1997-05-22 Abion Ohg Disposable applicator and Kit
US5695475A (en) * 1995-12-13 1997-12-09 Best, Jr.; Lester Syringe apparatus
US5749968A (en) * 1993-03-01 1998-05-12 Focal, Inc. Device for priming for improved adherence of gels to substrates
US5824012A (en) * 1993-05-12 1998-10-20 The Medicine Bottle Company, Inc. Nursing bottle with medication dispenser
US5879336A (en) * 1995-03-13 1999-03-09 Vygon Device for injecting a liquid
US6156010A (en) * 1997-06-17 2000-12-05 Injectimed, Inc. Method and apparatus for introducing an intravenous catheter
US6325806B1 (en) 1995-10-30 2001-12-04 Biomedical Enterprises, Inc. Materials collection system and uses thereof
WO2002070052A1 (en) * 2001-02-28 2002-09-12 Disetronic Licensing Ag Cannula support with a flexible cannula
US20030026849A1 (en) * 1997-10-15 2003-02-06 Thomas Jefferson University Nitric oxide donor compositions, methods, apparatus, and kits for preventing or alleviating vasoconstriction or vasospasm in a mammal
US6544233B1 (en) * 1999-10-18 2003-04-08 Terumo Kabushiki Kaisha Pre-filled syringe
US20030187404A1 (en) * 2001-09-25 2003-10-02 Ottfried Waldenburg Medication capsule, syringe used with medication capsule & method of administrating medication
US6648911B1 (en) 2000-11-20 2003-11-18 Avantec Vascular Corporation Method and device for the treatment of vulnerable tissue site
US6743194B2 (en) 2002-03-28 2004-06-01 Igal Sharon Multi-compartment syringe
US20040167480A1 (en) * 2003-02-21 2004-08-26 Advanced Medical Optics, Inc. Administration of multiple viscoelastic solutions with a multi-compartment syringe
US20040171988A1 (en) * 2002-03-08 2004-09-02 Pierino Moretti Combine needle and dilator device for central venous and arterial catheterization
US6949085B1 (en) 2003-02-13 2005-09-27 Best Jr Lester Safety syringe assembly
US20060178618A1 (en) * 2004-11-16 2006-08-10 Zimpl Aps Mouth adapter
WO2007006030A2 (en) * 2005-06-30 2007-01-11 Mallinckrodt Inc. Dual chamber syringe
US20070092451A1 (en) * 2005-10-25 2007-04-26 Loveridge Dan E Time indicating containers for dental compositions
US20070183986A1 (en) * 2006-02-06 2007-08-09 Ultradent Products, Inc. Methods and systems for mixing a multi-part fluoride varnish composition
US20070191792A1 (en) * 2003-12-08 2007-08-16 Galderma S.A. Device for dosing a product that is intended to be applied to the skin
US20070251839A1 (en) * 2006-05-01 2007-11-01 Ultradent Products, Inc. Syringe-in-syringe hollow inner barrel/plunger with integral seal and rupturable membrane and related kits, systems, and methods
US20070255201A1 (en) * 2006-05-01 2007-11-01 Ultradent Products, Inc. Time-indicating syringe mixing devices and related methods for storing and dispensing two-part dental compositions
US20070255204A1 (en) * 2006-05-01 2007-11-01 Ultradent Products, Inc Time-indicating syringe mixing devices and related methods for storing and dispensing two-part dental compositions
US20090118703A1 (en) * 2007-11-02 2009-05-07 Orilla Werhner C Drug delivery systems and methods
US20090124998A1 (en) * 2003-03-20 2009-05-14 Boston Scientific Scimed, Inc. Method for delivering therapeutic or diagnostic agents
WO2009089409A2 (en) * 2008-01-10 2009-07-16 Bausch & Lomb Incorporated Intravitreal injection system having coaxial cannulae and use thereof
US20090191279A1 (en) * 2008-01-29 2009-07-30 Ultradent Products, Inc. Fluoride varnish compositions including an organo phosphoric acid adhesion promoting agent
US20090292157A1 (en) * 2006-07-19 2009-11-26 Bruce John K Radiation Shielded Syringe Assembly and Uses Thereof
US20090318891A1 (en) * 2006-04-05 2009-12-24 Ronald Marcotte Delivery device, system, and method for delivering substances into blood vessels
US20100082015A1 (en) * 2008-09-30 2010-04-01 Tyco Healthcare Group Lp Device for Interfacing with Standard Luer Lock Syringes
US20100106138A1 (en) * 2008-10-29 2010-04-29 Biomet Biologics, Llc Method and apparatus for containing, transporting, and providing a material
US20100114067A1 (en) * 2008-10-31 2010-05-06 Warsaw Orthopedic, Inc. Multi-Chamber Mixing System
US20100323322A1 (en) * 2007-02-09 2010-12-23 Ultradent Products, Inc Syringe-in-Syringe Hollow Inner Barrel/Plunger With Integral Seal and Rupturable Membrane and Related Kits, Systems and Methods
WO2011110141A1 (en) * 2010-03-11 2011-09-15 Cybio Ag Pipetting unit and pipettor comprising such a pipetting unit, and pipette tip for use with such a pipettor
US20120029521A1 (en) * 2009-04-03 2012-02-02 Ebi, Llc Method and apparatus for delivering bone cement
WO2011137437A3 (en) * 2010-04-30 2012-02-02 Bayer Pharma Aktiengesellschaft Displacement syringe
US20120277664A1 (en) * 2011-04-28 2012-11-01 Macy Jr Bradford Method and device for the irrigation and drainage of wounds, tubes, and body orifices
WO2013029113A1 (en) 2011-09-02 2013-03-07 Unitract Syringe Pty Ltd Automatic reconstitution for dual chamber syringe
US20130274716A1 (en) * 2012-04-12 2013-10-17 Laurie Ausley Nelson Multiple Fluid Combining Syringe
US8931665B2 (en) * 2012-11-06 2015-01-13 Amit Gold Multi-compartment apparatus for in-situ mixing of a plurality of components before use
WO2015061341A1 (en) * 2013-10-21 2015-04-30 Accuro Technologies Inc. Double barrel syringe and method to use same for placement confirmation and joint space injection
US20150151052A1 (en) * 2010-01-05 2015-06-04 Allergan, Inc. Syringe
US20150374915A1 (en) * 2014-06-30 2015-12-31 Elwha Llc Active Lubrication of Penetrating Devices
WO2016049501A1 (en) * 2014-09-26 2016-03-31 Unitract Syringe Pty Ltd Concentric barrel drug containers and drug delivery pumps that allow mixing and delivery
US20160243310A1 (en) * 2013-10-18 2016-08-25 Sanofi-Aventis Deutschland Gmbh Medicament delivery device with two drive springs
US20160250416A1 (en) * 2015-02-27 2016-09-01 Purdue Research Foundation Perimeter fill syringe
US9539393B2 (en) 2013-06-04 2017-01-10 Unitract Syringe Pty Ltd Actuation mechanisms for dual chamber mixing syringes
WO2017009346A1 (en) 2015-07-13 2017-01-19 Kiomed Pharma Chitosan for mixing with a coagulable fluid
US20170020493A1 (en) * 2014-01-06 2017-01-26 Richard Hwang Organism Paracentesis Device And Method Thereof
US9694134B2 (en) 2013-09-16 2017-07-04 Zoetis Services Llc Assembly for sequentially delivering substances, and associated methods

Cited By (126)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3985122A (en) * 1975-06-04 1976-10-12 Medical Development Corporation Multi-piston syringe device
US4188949A (en) * 1977-07-05 1980-02-19 Becton, Dickinson & Company Sequential injection syringe
US4393882A (en) * 1979-08-31 1983-07-19 American Hospital Supply Corporation Method and device for collecting, transporting, and delivering micro samples of blood
US4313440A (en) * 1980-09-08 1982-02-02 Ashley Sheldon J Multipurpose double barrel syringe and method of manufacture of same
EP0076239A2 (en) * 1981-09-30 1983-04-06 Ivo Caselgrandi A syringe for use in hypodermic biopsy, featuring automatic plunger-return
EP0076239A3 (en) * 1981-09-30 1984-01-11 Ivo Caselgrandi A syringe for use in hypodermic biopsy, featuring automatic plunger-return
US4476866A (en) * 1982-08-06 1984-10-16 Thomas J. Fogarty Combined large and small bore syringe
EP0104791A2 (en) * 1982-09-10 1984-04-04 Avvari Rangaswamy Analgesic syringe
EP0104791A3 (en) * 1982-09-10 1984-09-12 Avvari Rangaswamy Analgesic syringe
US4512768A (en) * 1982-09-10 1985-04-23 Avvari Rangaswamy Analgesic syringe
US4583978A (en) * 1983-01-23 1986-04-22 Michael Porat Syringe
USRE32974E (en) * 1983-01-23 1989-07-04 Syringe
EP0153878A3 (en) * 1984-03-02 1986-05-28 Institute For Industrial Research And Standards An injection device
EP0153878A2 (en) * 1984-03-02 1985-09-04 Eolas - The Irish Science and Technology Agency An injection device
US5053019A (en) * 1984-03-02 1991-10-01 Institute For Industrial Research And Standards Injection device
US4834714A (en) * 1985-11-14 1989-05-30 Marcel Lascar Double compartment syringe
FR2589738A1 (en) * 1985-11-14 1987-05-15 Lascar Marcel Syringe double room
WO1987002896A1 (en) * 1985-11-14 1987-05-21 Marcel Lascar Double chamber syringe
US4655747A (en) * 1986-01-30 1987-04-07 Allen Jr Robert E Dual chambered syringe
US4929238A (en) * 1988-11-23 1990-05-29 Coeur Laboratories, Inc. Multi-pressure injector device
US4979942A (en) * 1989-10-16 1990-12-25 Johnson & Johnson Medical, Inc. Two component syringe delivery system
US5104375A (en) * 1989-10-16 1992-04-14 Johnson & Johnson Medical, Inc. Locking holder for a pair of syringes and method of use
US5078691A (en) * 1990-03-01 1992-01-07 Hamacher Edward N Multiple-dose fluid delivery system and method
US5354285A (en) * 1991-11-29 1994-10-11 Sergej Mikhailovich Masurik Injection syringe
US5222939A (en) * 1992-04-09 1993-06-29 Jonathan Tiefenbrun Instrument and associated method for applying biologically effective composition during surgery
US5372585A (en) * 1992-04-09 1994-12-13 Tiefenbrun; Jonathan Instrument and associated method for applying biologically effective composition during laparoscopic operation
GB2285794A (en) * 1992-09-30 1995-07-26 Intellectual Property Invest Multichamber container for blood or other fluid samples
WO1994007415A1 (en) * 1992-09-30 1994-04-14 Intellectual Property Investment Corporation Multichamber container for blood or other fluid samples
GB2285794B (en) * 1992-09-30 1996-01-17 Intellectual Property Invest Multichamber container for blood or other fluid samples
EP0695555A4 (en) * 1992-12-01 1996-03-27 Tetsuro Higashikawa Syringe
US5599312A (en) * 1992-12-01 1997-02-04 Higashikawa; Tetsuro Syringe
US5704918A (en) * 1992-12-01 1998-01-06 Higashikawa; Tetsuro Syringe
EP0695555A1 (en) * 1992-12-01 1996-02-07 HIGASHIKAWA, Tetsuro Syringe
US5749968A (en) * 1993-03-01 1998-05-12 Focal, Inc. Device for priming for improved adherence of gels to substrates
US5312336A (en) * 1993-04-14 1994-05-17 Habley Medical Technology Corporation Component mixing syringe
US5487750A (en) * 1993-05-12 1996-01-30 Burchett; Mark T. Nursing bottle with medication dispenser
US5383906A (en) * 1993-05-12 1995-01-24 Burchett; Mark T. Nursing bottle with medication dispenser
US5824012A (en) * 1993-05-12 1998-10-20 The Medicine Bottle Company, Inc. Nursing bottle with medication dispenser
US6015401A (en) * 1993-08-09 2000-01-18 Brackett; Jacqueline Darlene Methods for vessel cannulation
US5520657A (en) * 1993-08-09 1996-05-28 Sellers; Jackie Method and device for vessel location cannulation utilizing a unique needle and syringe device
US5630800A (en) * 1993-11-08 1997-05-20 Ferring Arzneimettel Gmbh Injection syringe for the missing and application of injection substances
US5496284A (en) * 1994-09-27 1996-03-05 Waldenburg; Ottfried Dual-chamber syringe & method
WO1996010430A3 (en) * 1994-09-27 1996-06-06 Ottfried Waldenburg Improved dual-chamber syringe & methods
US5879336A (en) * 1995-03-13 1999-03-09 Vygon Device for injecting a liquid
US5529189A (en) * 1995-08-02 1996-06-25 Daxor Corporation Syringe assembly for quantitative measurement of radioactive injectate and kit having same
US6325806B1 (en) 1995-10-30 2001-12-04 Biomedical Enterprises, Inc. Materials collection system and uses thereof
DE19543240A1 (en) * 1995-11-20 1997-05-22 Abion Ohg Disposable applicator and Kit
US5695475A (en) * 1995-12-13 1997-12-09 Best, Jr.; Lester Syringe apparatus
US6156010A (en) * 1997-06-17 2000-12-05 Injectimed, Inc. Method and apparatus for introducing an intravenous catheter
US6796966B2 (en) * 1997-10-15 2004-09-28 Jeffrey E. Thomas Apparatus, and kits for preventing of alleviating vasoconstriction or vasospasm in a mammal
US20030026849A1 (en) * 1997-10-15 2003-02-06 Thomas Jefferson University Nitric oxide donor compositions, methods, apparatus, and kits for preventing or alleviating vasoconstriction or vasospasm in a mammal
US6544233B1 (en) * 1999-10-18 2003-04-08 Terumo Kabushiki Kaisha Pre-filled syringe
US6648911B1 (en) 2000-11-20 2003-11-18 Avantec Vascular Corporation Method and device for the treatment of vulnerable tissue site
WO2002070052A1 (en) * 2001-02-28 2002-09-12 Disetronic Licensing Ag Cannula support with a flexible cannula
US7112188B2 (en) 2001-09-25 2006-09-26 Ottfried Waldenburg Medication capsule, syringe used with medication capsule and method of administrating medication
US20030187404A1 (en) * 2001-09-25 2003-10-02 Ottfried Waldenburg Medication capsule, syringe used with medication capsule & method of administrating medication
US20040171988A1 (en) * 2002-03-08 2004-09-02 Pierino Moretti Combine needle and dilator device for central venous and arterial catheterization
US6743194B2 (en) 2002-03-28 2004-06-01 Igal Sharon Multi-compartment syringe
US6949085B1 (en) 2003-02-13 2005-09-27 Best Jr Lester Safety syringe assembly
US20040167480A1 (en) * 2003-02-21 2004-08-26 Advanced Medical Optics, Inc. Administration of multiple viscoelastic solutions with a multi-compartment syringe
US8057459B2 (en) 2003-03-20 2011-11-15 Boston Scientific Scimed, Inc. Method for delivering therapeutic or diagnostic agents
US20090124998A1 (en) * 2003-03-20 2009-05-14 Boston Scientific Scimed, Inc. Method for delivering therapeutic or diagnostic agents
US7727204B2 (en) * 2003-12-08 2010-06-01 Galderma S.A. Device for dosing a product that is intended to be applied to the skin
US20070191792A1 (en) * 2003-12-08 2007-08-16 Galderma S.A. Device for dosing a product that is intended to be applied to the skin
US7654977B2 (en) * 2004-11-16 2010-02-02 Zimpl Aps Mouth adapter
US20060178618A1 (en) * 2004-11-16 2006-08-10 Zimpl Aps Mouth adapter
WO2007006030A3 (en) * 2005-06-30 2007-06-28 Mallinckrodt Inc Dual chamber syringe
US20100228121A1 (en) * 2005-06-30 2010-09-09 Katada Kazuhiro Dual Chamber Syringe
WO2007006030A2 (en) * 2005-06-30 2007-01-11 Mallinckrodt Inc. Dual chamber syringe
US7569185B2 (en) 2005-10-25 2009-08-04 Ultradent Products, Inc. Method for indicating shelf-life after mixing pre-dosed, pre-packaged two-part dental compositions
US20070092451A1 (en) * 2005-10-25 2007-04-26 Loveridge Dan E Time indicating containers for dental compositions
US20070106210A1 (en) * 2005-10-25 2007-05-10 Ultradent Products, Inc. Method for indicating shelf-life after mixing pre-dosed, pre-packaged two-part dental compositions
US20070183986A1 (en) * 2006-02-06 2007-08-09 Ultradent Products, Inc. Methods and systems for mixing a multi-part fluoride varnish composition
US20090318891A1 (en) * 2006-04-05 2009-12-24 Ronald Marcotte Delivery device, system, and method for delivering substances into blood vessels
US20100307935A1 (en) * 2006-05-01 2010-12-09 Ultradent Products, Inc. Syringe-in-syringe hollow inner barrel/plunger with integral seal and rupturable membrane and related kits, systems, and methods
US20070251839A1 (en) * 2006-05-01 2007-11-01 Ultradent Products, Inc. Syringe-in-syringe hollow inner barrel/plunger with integral seal and rupturable membrane and related kits, systems, and methods
US20090024082A1 (en) * 2006-05-01 2009-01-22 Ultradent Products, Inc. Time-Indicating Syringe Mixing Devices And Related Methods For Storing and Dispensing Two-Part Dental Compositions
US7776010B2 (en) 2006-05-01 2010-08-17 Ultradent Products, Inc. Syringe-in-syringe hollow inner barrel/plunger with integral seal and rupturable membrane and related kits, systems, and methods
US20070255204A1 (en) * 2006-05-01 2007-11-01 Ultradent Products, Inc Time-indicating syringe mixing devices and related methods for storing and dispensing two-part dental compositions
US20070255201A1 (en) * 2006-05-01 2007-11-01 Ultradent Products, Inc. Time-indicating syringe mixing devices and related methods for storing and dispensing two-part dental compositions
US8394052B2 (en) 2006-05-01 2013-03-12 Ultradent Products, Inc. Syringe-in-syringe hollow inner barrel/plunger with integral seal and rupturable membrane and related kits, systems, and methods
US20090292157A1 (en) * 2006-07-19 2009-11-26 Bruce John K Radiation Shielded Syringe Assembly and Uses Thereof
US9220577B2 (en) 2007-02-09 2015-12-29 Ultradent Products, Inc. Syringe-to-syringe mixing systems and related apparatus and methods
US8454558B2 (en) 2007-02-09 2013-06-04 Ultradent Products, Inc. Syringe-in-syringe hollow inner barrel/plunger with integral seal and rupturable membrane and related kits, systems and methods
US20100323322A1 (en) * 2007-02-09 2010-12-23 Ultradent Products, Inc Syringe-in-Syringe Hollow Inner Barrel/Plunger With Integral Seal and Rupturable Membrane and Related Kits, Systems and Methods
US20090118703A1 (en) * 2007-11-02 2009-05-07 Orilla Werhner C Drug delivery systems and methods
US8353862B2 (en) * 2007-11-02 2013-01-15 Allergan, Inc. Drug delivery systems and methods
US20100305514A1 (en) * 2008-01-10 2010-12-02 Bausch & Lomb Incorporated Intravitreal injection system having coaxial cannulae and use thereof
WO2009089409A2 (en) * 2008-01-10 2009-07-16 Bausch & Lomb Incorporated Intravitreal injection system having coaxial cannulae and use thereof
WO2009089409A3 (en) * 2008-01-10 2009-10-29 Bausch & Lomb Incorporated Intravitreal injection system having coaxial cannulae and use thereof
US20090191279A1 (en) * 2008-01-29 2009-07-30 Ultradent Products, Inc. Fluoride varnish compositions including an organo phosphoric acid adhesion promoting agent
US8383163B2 (en) 2008-01-29 2013-02-26 Ultradent Products, Inc. Fluoride varnish compositions including an organo phosphoric acid adhesion promoting agent
US8852561B2 (en) 2008-01-29 2014-10-07 Ultradent Products, Inc. Fluoride varnish compositions including an organo phosphoric acid adhesion promoting agent
US8152778B2 (en) 2008-09-30 2012-04-10 Tyco Healthcare Group Lp Device for interfacing with standard luer lock syringes
US20100082015A1 (en) * 2008-09-30 2010-04-01 Tyco Healthcare Group Lp Device for Interfacing with Standard Luer Lock Syringes
US9370346B2 (en) 2008-10-29 2016-06-21 Biomet Biologics, Llc Method and apparatus for containing, transporting, and providing a material
US8523805B2 (en) 2008-10-29 2013-09-03 Biomet Biologics, Llc Method and apparatus for containing, transporting, and providing a material
WO2010053765A1 (en) * 2008-10-29 2010-05-14 Biomet Biologics, Llc Method and apparatus for containing, transporting, and providing a material
US20100106138A1 (en) * 2008-10-29 2010-04-29 Biomet Biologics, Llc Method and apparatus for containing, transporting, and providing a material
US20100114067A1 (en) * 2008-10-31 2010-05-06 Warsaw Orthopedic, Inc. Multi-Chamber Mixing System
US9060826B2 (en) * 2009-04-03 2015-06-23 Ebi, Llc Method and apparatus for delivering bone cement
US20120029521A1 (en) * 2009-04-03 2012-02-02 Ebi, Llc Method and apparatus for delivering bone cement
US20150151052A1 (en) * 2010-01-05 2015-06-04 Allergan, Inc. Syringe
US9750884B2 (en) * 2010-01-05 2017-09-05 Allergan, Inc. Syringe
WO2011110141A1 (en) * 2010-03-11 2011-09-15 Cybio Ag Pipetting unit and pipettor comprising such a pipetting unit, and pipette tip for use with such a pipettor
JP2013525013A (en) * 2010-04-30 2013-06-20 バイエル ファーマ アクチエンゲゼルシャフト Replacement syringe
CN103037921A (en) * 2010-04-30 2013-04-10 拜耳药业股份公司 Displacement Syringe
WO2011137437A3 (en) * 2010-04-30 2012-02-02 Bayer Pharma Aktiengesellschaft Displacement syringe
US20120277664A1 (en) * 2011-04-28 2012-11-01 Macy Jr Bradford Method and device for the irrigation and drainage of wounds, tubes, and body orifices
CN103764196A (en) * 2011-09-02 2014-04-30 尤尼特拉克特注射器公司 Automatic reconstitution for dual chamber syringe
US9821118B2 (en) 2011-09-02 2017-11-21 Unl Holdings Llc Automatic reconstitution for dual chamber syringe
WO2013029113A1 (en) 2011-09-02 2013-03-07 Unitract Syringe Pty Ltd Automatic reconstitution for dual chamber syringe
EP2750733A1 (en) * 2011-09-02 2014-07-09 Unitract Syringe Pty Ltd Automatic reconstitution for dual chamber syringe
EP2750733A4 (en) * 2011-09-02 2015-04-22 Unitract Syringe Pty Ltd Automatic reconstitution for dual chamber syringe
US20130274716A1 (en) * 2012-04-12 2013-10-17 Laurie Ausley Nelson Multiple Fluid Combining Syringe
US8808233B2 (en) * 2012-04-12 2014-08-19 Laurie Ausley Nelson Multiple fluid combining syringe
US8931665B2 (en) * 2012-11-06 2015-01-13 Amit Gold Multi-compartment apparatus for in-situ mixing of a plurality of components before use
US9539393B2 (en) 2013-06-04 2017-01-10 Unitract Syringe Pty Ltd Actuation mechanisms for dual chamber mixing syringes
US9694134B2 (en) 2013-09-16 2017-07-04 Zoetis Services Llc Assembly for sequentially delivering substances, and associated methods
US20160243310A1 (en) * 2013-10-18 2016-08-25 Sanofi-Aventis Deutschland Gmbh Medicament delivery device with two drive springs
WO2015061341A1 (en) * 2013-10-21 2015-04-30 Accuro Technologies Inc. Double barrel syringe and method to use same for placement confirmation and joint space injection
US20170020493A1 (en) * 2014-01-06 2017-01-26 Richard Hwang Organism Paracentesis Device And Method Thereof
US20150374915A1 (en) * 2014-06-30 2015-12-31 Elwha Llc Active Lubrication of Penetrating Devices
WO2016049501A1 (en) * 2014-09-26 2016-03-31 Unitract Syringe Pty Ltd Concentric barrel drug containers and drug delivery pumps that allow mixing and delivery
US20160250416A1 (en) * 2015-02-27 2016-09-01 Purdue Research Foundation Perimeter fill syringe
WO2017009346A1 (en) 2015-07-13 2017-01-19 Kiomed Pharma Chitosan for mixing with a coagulable fluid

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