CN105534710B - The method of solution for skin test dispenser and preparing solution for skin test - Google Patents
The method of solution for skin test dispenser and preparing solution for skin test Download PDFInfo
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- CN105534710B CN105534710B CN201610056865.9A CN201610056865A CN105534710B CN 105534710 B CN105534710 B CN 105534710B CN 201610056865 A CN201610056865 A CN 201610056865A CN 105534710 B CN105534710 B CN 105534710B
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
- A61J1/22—Arrangements for transferring or mixing fluids, e.g. from vial to syringe with means for metering the amount of fluid
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
- A61J1/2089—Containers or vials which are to be joined to each other in order to mix their contents
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Abstract
The method of solution for skin test dispenser and preparing solution for skin test, including the syringe piston body in injector cartridge and insertion syringe cylinder body, injector cartridge is made up of main cylinder and micro- metering cylinder, and micro- metering cylinder is connected to the front end of main cylinder, micro- metering barrel front end connecting needle；Syringe piston body is made up of primary piston body and sub- piston body, the inside of primary piston body offers sub- plunger shaft, in sub- piston body intron plunger shaft, the rear end connection main piston rod of primary piston body, the rear end connexon piston rod of sub- piston body, main piston rod axially inside offers inner chamber, and sub- piston rod passes through from the inner chamber, and the sub- piston body coordinates with micro- metering cylinder.The solution for skin test dispenser of the present invention and the method for preparing solution for skin test, the step of simplifying preparing solution for skin test, the possibility of liquid medicine contamination is reduced, number of operations is reduced, and precision preparation improves, and is not easy to make mistakes；Accurate measurement, noresidue when dispenser empties medicament, bubble-free is sterile, easy to operate.
Description
Technical field
The present invention relates to area of medical devices, more particularly to a kind of solution for skin test dispenser and the method for preparing solution for skin test.
Background technology
In the prior art, preparing solution for skin test, which usually requires 4 steps, could complete, it is necessary to using syringe by repeatedly suction medicine
Liquid, it is easily contaminated, and the precision made up a prescription is inadequate, and operation is also inconvenient.
By taking benzylpenicillin skin-test solution as an example, the U/ bottles of penicillin 800,000.
The first step, 4ml physiological saline is taken with 10ml syringes, injects in 800,000 U penicillin bottle, dissolves penicillin,
Obtain 200,000 U/ml penicillin decoction；
Second step, the penicillin medicine that takes 20 ten thousand U/mls is inserted in 800,000 U dissolved penicillin bottle with 1ml skin test injection syringes
Liquid 0.1ml, it is inserted into after extraction in normal saline bottle and sucks physiological saline to 1ml, obtain 20,000 U/ml penicillin decoction；
3rd step, the penicillin decoction of 20,000 U/ml in 1ml skin test injection syringes is discharged into 0.9ml, is inserted into normal saline bottle
Middle suction physiological saline obtains 2,000 U/ml penicillin decoction to 1ml；
4th step, the penicillin decoction of 2,000 U/ml in 1ml skin test injection syringes is discharged into 0.75ml, is inserted into physiological saline
Physiological saline is sucked in bottle to 1ml, obtains 500U/ml penicillin decoction；
5th step, the penicillin decoction 0.1ml for taking 500U/ml with skin test injection syringe make skin test (i.e. 50U).
As can be seen that aforesaid operations step number is cumbersome, repeatedly extract micro decoction, thus can not accurate measurement, so as to influence
Clinical skin test effect, and easily cause liquid medicine contamination.
The content of the invention
It is an object of the invention to provide a kind of solution for skin test dispenser and the method for preparing solution for skin test, to solve above-mentioned technology
Problem.
The technical problems to be solved by the invention are realized using following technical scheme：
Solution for skin test dispenser, it is characterised in that：Including the syringe piston in injector cartridge and insertion syringe cylinder body
Body, the injector cartridge are made up of main cylinder and micro- metering cylinder, and micro- metering cylinder is connected to the front end of main cylinder, micro-
Measure barrel front end connecting needle；The syringe piston body is made up of primary piston body and sub- piston body, the inside of primary piston body
Offer sub- plunger shaft, in sub- piston body intron plunger shaft, the rear end connection main piston rod of the primary piston body, sub- piston body
Rear end connexon piston rod, the main piston rod axially inside offers inner chamber, and sub- piston rod passes through from the inner chamber, institute
Sub- piston body is stated with micro- metering cylinder to coordinate.
Graduation mark, micro- graduation mark measured on cylinder are provided with the main cylinder, micro- metering cylinder and sub- piston rod
For measuring accuracy higher than the graduation mark measuring accuracy on main cylinder, the graduation mark on sub- piston rod is used for liquid in micro- hopper body
Measure, the graduation mark metering on sub- piston rod is equal to the graduation mark metering on micro- metering cylinder.
Graduation mark, micro- graduation mark measured on cylinder are provided with the main cylinder, micro- metering cylinder and sub- piston rod
Measuring accuracy is higher than the graduation mark measuring accuracy on sub- piston rod, and the graduation mark measuring accuracy on sub- piston rod is higher than on main cylinder
Graduation mark measuring accuracy, the graduation mark on sub- piston rod is used for the metering of sub- piston intracavity liquid.
Preferably, also including being used for the adapter for being connected two syringes, the adapter both ends are female Luer.
Preferably, the sub- piston body is a cylinder, coordinate with micro- metering cylinder.
Preferably, the length of the sub- piston body is more than the three times of micro- metering barrel lenght.
Preferably, the sub- piston body is made up of two sections of cylinders, the cylinder diameter of its middle front part is less than rear portion
Cylinder diameter, anterior cylinder coordinate with micro- metering cylinder.
Preferably, length and micro- hopper body phase of the cylinder of the sub- piston body front portion etc., the cylinder at rear portion
Length is more than two times of micro- metering barrel lenght.
A kind of method using solution for skin test dispenser preparing solution for skin test, it is characterised in that comprise the following steps：
Using solution for skin test dispenser, sub- piston body front end and primary piston body front end is kept to align first, in micro- metering cylinder
Front end is inserted in medicament solvent bottle after setting up injection needle, a certain amount of solvent for pulling main piston rod suction to be computed, after extraction
It is inserted into flask for medicinal preparations, injects a certain amount of solvent being computed, be completely dissolved medicament well mixed, obtain dilute liquid medicine；To
It is the step of injection solvent in flask for medicinal preparations：First main piston rod is pressed forward a certain amount of, then sub- piston rod pressed forward, until son is living
Cock body front end and micro- metering barrel front end maintain an equal level only；
Then the sub- piston rod for solution for skin test dispenser of pulling back again, the dilute liquid medicine of amount of calculation is quantitatively aspirated, by dilute liquid medicine
With medicament solvent mixed diluting in solution for skin test dispenser main cylinder, the solution for skin test for needing concentration is produced；
Then the solution for skin test in solution for skin test dispenser is quantitatively transferred in skin test liquid syringe, you can for patient's skin
Examination.
The beneficial effects of the invention are as follows：
The solution for skin test dispenser of the present invention is a kind of knockdown primary and secondary syringe, has heavy dose of cylinder and micro- metering
Cylinder, also with primary piston body and sub- piston body, sub- piston body coordinates with micro- metering cylinder to be completed accurately to aspirate micro- metering medicine
The task of agent, primary piston body coordinate the completing to aspirate heavy dose of medicament of the task with heavy dose of cylinder.
The solution for skin test dispenser of the present invention and the method for preparing solution for skin test, the step of simplifying preparing solution for skin test, reduce medicine
The possibility of liquid pollution, number of operations are reduced, and precision preparation improves, and is not easy to make mistakes；Accurate measurement, when dispenser empties medicament
Noresidue, bubble-free is sterile, easy to operate.
Brief description of the drawings
Fig. 1 is the solution for skin test dispenser working state schematic representation (one) of embodiment 1；
Fig. 2 is the solution for skin test dispenser working state schematic representation (two) of embodiment 1；
Fig. 3 is the solution for skin test dispenser working state schematic representation (three) of embodiment 1；
Fig. 4 is the solution for skin test dispenser working state schematic representation (four) of embodiment 1；
Fig. 5 is the solution for skin test dispenser working state schematic representation (five) of embodiment 1；
Fig. 6 is the structural representation of adapter；
Fig. 7 is the solution for skin test dispenser working state schematic representation (one) of embodiment 2；
Fig. 8 is the solution for skin test dispenser working state schematic representation (two) of embodiment 2；
Fig. 9 is the solution for skin test dispenser working state schematic representation (three) of embodiment 2；
Figure 10 is the solution for skin test dispenser working state schematic representation (four) of embodiment 2；
Figure 11 is the solution for skin test dispenser working state schematic representation (five) of embodiment 2.
Wherein：1. syringe needle；2. micro- metering cylinder；3. main cylinder；4. sub- piston body；5. primary piston body；6. main piston rod；7.
Sub- piston rod；8. sub- plunger shaft.
Embodiment
In order that the technical means, the inventive features, the objects and the advantages of the present invention are easy to understand, tie below
Specific embodiments and the drawings are closed, the present invention is expanded on further, but following embodiments are only the preferred embodiments of the present invention, not
All.Based on the embodiment in embodiment, those skilled in the art are obtained on the premise of creative work is not made
Other embodiments, belong to protection scope of the present invention.
The specific embodiment of the present invention is described below in conjunction with the accompanying drawings.
Embodiment 1
As shown in figures 1 to 6, the syringe piston in solution for skin test dispenser, including injector cartridge and insertion syringe cylinder body
Body, injector cartridge are made up of main cylinder 3 and micro- metering cylinder 2, and micro- metering cylinder 2 is connected to the front end of main cylinder 3, micro- metering
The front end connecting needle 1 of cylinder 2；Syringe piston body is made up of primary piston body 5 and sub- piston body 4, and the inside of primary piston body 5 opens up
There is a sub- plunger shaft 8, in the sub- intron plunger shaft 8 of piston body 4, the rear end connection main piston rod 6 of primary piston body 5, sub- piston body 4
Rear end connexon piston rod 7, main piston rod 6 axially inside offer inner chamber, and sub- piston rod 7 passes through from the inner chamber, and son is living
The front end of cock body 4 coordinates with micro- metering cylinder 2；
Graduation mark, micro- metering cylinder 2 and sub- piston rod 7 are provided with main cylinder 3, sub- piston rod 7 and micro- metering cylinder 2
On graduation mark measuring accuracy higher than the graduation mark measuring accuracy on main cylinder 3；Sub- piston body 4 is a cylinder, with micro- metering
Cylinder 2 coordinates, and the length of sub- piston body 4 is more than the three times of micro- metering length of cylinder 2；
Also include being used for the adapter for being connected two syringes, the adapter both ends are female Luer.
Embodiment 2
As illustrated in figs. 6-11, the syringe in solution for skin test dispenser, including injector cartridge and insertion syringe cylinder body is lived
Cock body, injector cartridge are made up of main cylinder 3 and micro- metering cylinder 2, and micro- metering cylinder 2 is connected to the front end of main cylinder 3, micro- meter
The front end connecting needle 1 of graduated cylinder body 2；Syringe piston body is made up of primary piston body 5 and sub- piston body 4, and the inside of primary piston body 5 is opened
Provided with sub- plunger shaft 8, in the sub- intron plunger shaft 8 of piston body 4, the rear end connection main piston rod 6 of primary piston body 5, sub- piston body 4
Rear end connexon piston rod 7, main piston rod 6 axially inside offers inner chamber, and sub- piston rod 7 passes through from the inner chamber, son
The front end of piston body 4 coordinates with micro- metering cylinder 2；
Graduation mark, micro- metering cylinder 2 and sub- piston rod 7 are provided with main cylinder 3, sub- piston rod 7 and micro- metering cylinder 2
On graduation mark measuring accuracy higher than the graduation mark measuring accuracy on main cylinder 3；Sub- piston body 4 is made up of two sections of cylinders, its
The cylinder diameter of middle front part is less than the cylinder diameter at rear portion, and anterior cylinder coordinates with micro- metering cylinder 2；Sub- piston body
The length of 4 anterior cylinders and micro- metering cylinder 2 are equal, and the cylinder length at rear portion is two times of micro- metering length of cylinder 2
More than；
Also include being used for the adapter for being connected two syringes, the adapter both ends are female Luer.
The dosage of solution for skin test：
Embodiment 3
The U/ bottles of penicillin 800,000,
Existing method prepares benzylpenicillin skin-test solution：
The first step, 4ml physiological saline is taken with 10ml syringes, inserts in 800,000 U penicillin bottle, dissolves penicillin,
Obtain 200,000 U/ml penicillin decoction；
Second step, the penicillin decoction that takes 20 ten thousand U/mls is inserted in 800,000 U penicillin bottles of dissolving with 1ml skin test injection syringes
0.1ml, it is inserted into after extraction in normal saline bottle and sucks physiological saline to 1ml, obtain 20,000 U/ml penicillin decoction；
3rd step, the penicillin decoction of 20,000 U/ml in 1ml skin test injection syringes is discharged into 0.9ml, is inserted into normal saline bottle
Middle suction physiological saline obtains 2,000 U/ml penicillin decoction to 1ml；
4th step, the penicillin decoction of 2,000 U/ml in 1ml skin test injection syringes is discharged into 0.75ml, is inserted into physiological saline
Physiological saline is sucked in bottle to 1ml, obtains 500U/ml penicillin decoction；
5th step, the penicillin decoction 0.1ml for taking 500U/ml with skin test injection syringe make skin test (i.e. 50U).
The present processes prepare benzylpenicillin skin-test solution：
Solution for skin test dispenser one is taken, first sub- piston body front end and primary piston body front end are alignd, then in micro- metering cylinder
Front end is inserted in normal saline bottle after setting up injection needle, is pulled primary piston body suction 13.2ml physiological saline, is inserted again after extraction
In the penicillin bottle for entering 800,000 U, main piston rod is first pushed forward to injection 3ml physiological saline, then sub- piston rod is pushed forward
Injection 0.2ml physiological saline (now sub- piston body front end and micro- metering barrel front end are just alignd), 3.2ml physiology is injected altogether
Salt solution is completely dissolved penicillin well mixed, obtains dilute liquid medicine into penicillin bottle；Then pull back again solution for skin test dispenser
Sub- piston rod, aspirate in 0.02ml penicillin dilute liquid medicine to solution for skin test dispenser main cylinder with remaining 10ml physiological saline
Mixing, produce 500U/ml available benzylpenicillin skin-test solution；
Then set up adapter with 1ml skin test liquid syringes to be connected with the micro- metering cylinder of solution for skin test dispenser, quantitative transfer
Benzylpenicillin skin-test solution is into 1ml skin test liquid syringes, you can for clinical skin test.Operation step number is few above, and precision improves, and is not easy
Make mistakes；
Embodiment 4
Ampicillin 1g/ bottles, Cloxacillin 1g/ bottles, ampicillin sodium and cloxacillin sodium 1g/ bottles, azlocillin Sulbactam
Sodium 1g/ bottles：
Existing method：
1st, medicine 10ml syringes needed for more than add physiological saline 4ml to dissolve, and it is 250mg/ml decoctions to obtain concentration.
2nd, physiological saline 0.9ml is extracted again after taking upper liquid (250mg/ml) 0.1ml with 1ml skin test injection syringes, and obtaining concentration is
(25mg/ml) decoction.
3rd, it is that (25mg/ml) decoction discharges 0.9ml by concentration in skin test injection syringe, then sucks physiological saline 0.9ml, obtains dense
Spend for (2.5mg/ml) decoction.
It is that (2.5mg/ml) decoction discharges 0.8ml by concentration in skin test injection syringe, then sucks physiological saline 0.8ml, obtains dense
Spend for (0.5mg/ml) skin test decoction.
Upper liquid 0.1ml is taken to make skin test (i.e. 0.05mg).
The present processes：
1st, solution for skin test dispenser one is taken, sub- piston body front end and primary piston body front end are alignd, then in micro- metering cylinder
Front end is set up and inserted in normal saline bottle after injection needle, pulls primary piston body suction 4ml physiological saline, be inserted into after extraction with
In apothecary jar needed for upper, main piston rod and sub- piston rod are pushed respectively, 4ml (will be contained in micro- hopper body) in solution for skin test dispenser
Physiological saline be all injected into apothecary jar needed for the above, be well mixed complete drug dissolution, obtain dilute liquid medicine；To the above
It is the step of saline injection in required apothecary jar：Main piston rod is first pressed to forward bottom, then sub- piston rod is pushed away forward
Pressure, sub- piston body front end and micro- metering barrel front end is set just to align.
2nd, the sub- piston rod for solution for skin test dispenser of pulling back, the dilute liquid medicine of 0.02ml in apothecary jar needed for the above is aspirated, is pulled out
Go out injection needle, be inserted into normal saline bottle and aspirate 10ml physiological saline with 0.02ml dilute liquid medicines in the main cylinder of solution for skin test dispenser
Mixing in vivo, produce 0.5mg/ml solution for skin test；
Then set up adapter with 1ml skin test liquid syringes to be connected with the micro- metering cylinder of solution for skin test dispenser, quantitative transfer
Medicine solution for skin test is into 1ml skin test liquid syringes needed for above, you can for clinical skin test.
Operation step number is few above, and precision improves, and is not easy to make mistakes.
Embodiment 5
XiLin 0.5g/ bottles, ampicillin 0.5g/ bottles draw in mezlocillin 0.5g/ bottles, group
Existing method：
1st, medicine 10ml syringes needed for more than add physiological saline 2ml to dissolve, and it is 250mg/ml decoctions to obtain concentration.
2nd, physiological saline 0.9ml is extracted again after taking upper liquid (250mg/ml) 0.1ml with 1ml skin test injection syringes, and obtaining concentration is
(25mg/ml) decoction.
3rd, it is that (25mg/ml) decoction discharges 0.9ml by concentration in skin test injection syringe, then sucks physiological saline 0.9ml, obtains dense
Spend for (2.5mg/ml) decoction.
4th, it is that (2.5mg/ml) decoction discharges 0.8ml by concentration in skin test injection syringe, then sucks physiological saline 0.8ml, obtains
Concentration is (0.5mg/ml) skin test decoction.
5th, upper liquid 0.1ml is taken to make skin test (i.e. 0.05mg).
The method of the application preparing solution for skin test：
1st, solution for skin test dispenser one is taken, sub- piston body front end and primary piston body front end are alignd, then in micro- metering cylinder
Front end is set up and inserted in normal saline bottle after injection needle, pulls primary piston body suction 2ml physiological saline, be inserted into after extraction with
In apothecary jar needed for upper, main piston rod and sub- piston rod are pushed respectively, 2ml (will be contained in micro- hopper body) in solution for skin test dispenser
Physiological saline be all injected into apothecary jar needed for the above, be well mixed complete drug dissolution, obtain dilute liquid medicine；To the above
It is the step of saline injection in required apothecary jar：Main piston rod is first pressed to forward bottom, then sub- piston rod is pushed away forward
Pressure, sub- piston body front end and micro- metering barrel front end is set just to align.
2nd, the sub- piston rod for solution for skin test dispenser of pulling back, the dilute liquid medicine of 0.02ml in apothecary jar needed for the above is aspirated, is pulled out
Go out injection needle, be inserted into normal saline bottle and aspirate 10ml physiological saline with 0.02ml dilute liquid medicines in the main cylinder of solution for skin test dispenser
Mixing in vivo, produce 0.5mg/ml solution for skin test；
Then set up adapter with 1ml skin test liquid syringes to be connected with the micro- metering cylinder of solution for skin test dispenser, quantitative transfer
Medicine solution for skin test is into 1ml skin test liquid syringes needed for above, you can for clinical skin test.
Operation step number is few above, and precision improves, and is not easy to make mistakes.
Embodiment 6
Ceftazidime sulbactam 0.75g/ bottles
The method of prior art preparing solution for skin test：
1st, medicine 10ml syringes needed for more than add physiological saline 3ml to dissolve, and it is 250mg/ml decoctions to obtain concentration.
2nd, physiological saline 0.9ml is extracted again after taking upper liquid (250mg/ml) 0.1ml with 1ml skin test injection syringes, and obtaining concentration is
(25mg/ml) decoction.
3rd, it is that (25mg/ml) decoction discharges 0.9ml by concentration in skin test injection syringe, then sucks physiological saline 0.9ml, obtains dense
Spend for (2.5mg/ml) decoction.
4th, it is that (2.5mg/ml) decoction discharges 0.8ml by concentration in skin test injection syringe, then sucks physiological saline 0.8ml, obtains
Concentration is (0.5mg/ml) skin test decoction.
5th, upper liquid 0.1ml is taken to make skin test (i.e. 0.05mg).
The method of the application preparing solution for skin test：
1st, solution for skin test dispenser one is taken, sub- piston body front end and primary piston body front end are alignd, then in micro- metering cylinder
Front end is set up and inserted in normal saline bottle after injection needle, pulls primary piston body suction 3ml physiological saline, be inserted into after extraction with
In apothecary jar needed for upper, main piston rod and sub- piston rod are pushed respectively, 3ml (will be contained in micro- hopper body) in solution for skin test dispenser
Physiological saline be all injected into apothecary jar needed for the above, be well mixed complete drug dissolution, obtain dilute liquid medicine；To the above
It is the step of saline injection in required apothecary jar：Main piston rod is first pressed to forward bottom, then sub- piston rod is pushed away forward
Pressure, sub- piston body front end and micro- metering barrel front end is set just to align.
2nd, the sub- piston rod for solution for skin test dispenser of pulling back, the dilute liquid medicine of 0.02ml in apothecary jar needed for the above is aspirated, is pulled out
Go out injection needle, be inserted into normal saline bottle and aspirate 10ml physiological saline with 0.02ml dilute liquid medicines in the main cylinder of solution for skin test dispenser
Mixing in vivo, produce 0.5mg/ml solution for skin test；
Then set up adapter with 1ml skin test liquid syringes to be connected with the micro- metering cylinder of solution for skin test dispenser, quantitative transfer
Medicine solution for skin test is into 1ml skin test liquid syringes needed for above, you can for clinical skin test.
Above number of operations is reduced, and precision improves, and is not easy to make mistakes.
Experimental data
First, benzylpenicillin skin-test solution prepares contrast experiment
Ask the first and second the third three experienced nurses respectively with conventional syringe method and this Shen in a Grade A hospital nursing dept.
Solution for skin test dispenser method please does benzylpenicillin skin-test solution preparation to 800,000 units/bottle penicillin, and (benzylpenicillin skin-test solution standard is dense
Spend 500 units per mls) contrast experiment (repeating three times), our high performance liquid chromatography as defined in Chinese Pharmacopoeia 2015 editions
Method carries out assay, and its result is as follows：
Result above can be seen that the benzylpenicillin skin-test solution prepared with solution for skin test dispenser because operation step number is few, solution for skin test
Dispenser precision is high, so concentration and normal concentration error are small, clinically using more reliable.Solution for skin test concentration and defined mark
Quasi- concentration error too big (exceeding ± 10%) can cause adverse reaction or not have skin test effect.
In the description of the invention, it is to be understood that term " " center ", " longitudinal direction ", " transverse direction ", " length ", " width ",
" thickness ", " on ", " under ", "front", "rear", "left", "right", " vertical ", " level ", " top ", " bottom ", " interior ", " outer ", " up time
The orientation or position relationship of the instruction such as pin ", " counterclockwise " are based on orientation shown in the drawings or position relationship, are for only for ease of
Description is of the invention to be described with simplified, rather than the device or element of instruction or hint meaning must be with specific orientation, Yi Te
Fixed azimuth configuration and operation, therefore be not considered as limiting the invention.
In addition, term " first ", " second " are only used for describing purpose, and it is not intended that instruction or hint relative importance
Or the implicit quantity for indicating indicated technical characteristic.Thus, define " first ", the feature of " second " can be expressed or
Implicitly include one or more this feature.In the description of the invention, " multiple " are meant that two or more,
Unless otherwise specifically defined.
In the present invention, unless otherwise clearly defined and limited, term " installation ", " connected ", " connection ", " fixation " etc.
Term should be interpreted broadly, for example, it may be being fixedly connected or being detachably connected, or be integrally connected；It can be machine
Tool connects or electrical connection；Can be joined directly together, can also be indirectly connected by intermediary, can be two members
Connection inside part.For the ordinary skill in the art, above-mentioned term can be understood in this hair as the case may be
Concrete meaning in bright.
In the present invention, unless otherwise clearly defined and limited, fisrt feature second feature it " on " or it " under "
Can directly it be contacted including the first and second features, it is not directly to contact but pass through it that can also include the first and second features
Between other characterisation contact.Moreover, fisrt feature second feature " on ", " top " and " above " to include first special
Sign is directly over second feature and oblique upper, or is merely representative of fisrt feature level height and is higher than second feature.Fisrt feature exists
Second feature " under ", " lower section " and " following " fisrt feature that includes are immediately below second feature and obliquely downward, or be merely representative of
Fisrt feature level height is less than second feature.
General principle, principal character and the advantages of the present invention of the present invention has been shown and described above.The technology of the industry
For personnel it should be appreciated that the present invention is not limited to the above embodiments, that described in above-described embodiment and specification is only the present invention
Preference, be not intended to limit the present invention, without departing from the spirit and scope of the present invention, the present invention also have it is various
Changes and improvements, these changes and improvements all fall within the protetion scope of the claimed invention.The claimed scope of the invention is by institute
Attached claims and its equivalent thereof.
Claims (9)
1. solution for skin test dispenser, it is characterised in that：Including injector cartridge and insertion syringe cylinder body in syringe piston body,
The injector cartridge is made up of main cylinder and micro- metering cylinder, and micro- metering cylinder is connected to the front end of main cylinder, micro- meter
Measure barrel front end connecting needle；The syringe piston body is made up of primary piston body and sub- piston body, and the inside of primary piston body is opened
Provided with sub- plunger shaft, in sub- piston body intron plunger shaft, the rear end connection main piston rod of the primary piston body, sub- piston body
Rear end connexon piston rod, the main piston rod axially inside offer inner chamber, and sub- piston rod passes through from the inner chamber, described
Sub- piston body coordinates with micro- metering cylinder.
2. solution for skin test dispenser according to claim 1, it is characterised in that：The main cylinder, micro- metering cylinder and son are lived
Graduation mark is provided with stopper rod, micro- graduation mark measuring accuracy measured on cylinder is higher than the graduation mark metering essence on main cylinder
Spend, metering of the graduation mark on sub- piston rod for liquid in micro- hopper body, the graduation mark metering on sub- piston rod is equal to
Graduation mark metering on micro- metering cylinder.
3. solution for skin test dispenser according to claim 1, it is characterised in that：The main cylinder, micro- metering cylinder and son are lived
Graduation mark is provided with stopper rod, micro- graduation mark measuring accuracy measured on cylinder is higher than the graduation mark metering essence on sub- piston rod
Degree, graduation mark measuring accuracy on sub- piston rod is higher than the graduation mark measuring accuracy on main cylinder, the graduation mark on sub- piston rod
Metering for sub- piston intracavity liquid.
4. solution for skin test dispenser according to claim 1, it is characterised in that：Also include being used for the rank for being connected two syringes
Joint, the adapter both ends are female Luer.
5. solution for skin test dispenser according to claim 1, it is characterised in that：The sub- piston body is a cylinder, and micro-
Cylinder is measured to coordinate.
6. solution for skin test dispenser according to claim 5, it is characterised in that：The length of the sub- piston body is micro- hopper
It is more than the three times of body length.
7. solution for skin test dispenser according to claim 1, it is characterised in that：The sub- piston body is by two sections of cylinder structures
Into the cylinder diameter of its middle front part is less than the cylinder diameter at rear portion, and anterior cylinder coordinates with micro- metering cylinder.
8. solution for skin test dispenser according to claim 7, it is characterised in that：The length of the anterior cylinder of the sub- piston body
Degree and micro- hopper body phase etc., the cylinder length at rear portion are more than two times of micro- metering barrel lenght.
A kind of 9. method using the solution for skin test dispenser preparing solution for skin test of claim 1,2 or 3, it is characterised in that including
Following steps：
Using solution for skin test dispenser, sub- piston body front end and primary piston body front end is kept to align first, in micro- metering barrel front end
Insert in medicament solvent bottle, a certain amount of solvent for pulling main piston rod suction to be computed, inserted again after extraction after setting up injection needle
Enter in flask for medicinal preparations, inject a certain amount of solvent being computed, be completely dissolved medicament well mixed, obtain dilute liquid medicine；To medicament
It is the step of injection solvent in bottle：First main piston rod is pressed forward a certain amount of, then sub- piston rod pressed forward, until sub- piston body
Front end and micro- metering barrel front end maintain an equal level only；
Then the sub- piston rod for solution for skin test dispenser of pulling back again, the dilute liquid medicine of amount of calculation is quantitatively aspirated, by dilute liquid medicine in skin
With medicament solvent mixed diluting in test solution dispenser main cylinder, the solution for skin test for needing concentration is produced；
Then the solution for skin test in solution for skin test dispenser is quantitatively transferred in skin test liquid syringe, you can for patient's skin test.
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Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN106404098B (en) * | 2016-08-30 | 2019-11-22 | 深圳市有为环境科技有限公司 | A kind of metering system |
| CN107179219A (en) * | 2017-07-13 | 2017-09-19 | 海南聚能科技创新研究院有限公司 | A kind of two-stage metered shot device |
| CN113181476A (en) * | 2021-04-22 | 2021-07-30 | 张静 | Skin test needle dispenses fast |
| CN113713871A (en) * | 2021-08-26 | 2021-11-30 | 上海安集协康生物技术股份有限公司 | Syringe |
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| US3749084A (en) * | 1971-05-03 | 1973-07-31 | A Cucchiara | Sequentially dispensing syringe with multiple needle assembly |
| CN201418927Y (en) * | 2009-05-15 | 2010-03-10 | 李淑美 | One-tube double-liquid syringe |
| CN203915674U (en) * | 2014-06-26 | 2014-11-05 | 山东威高集团医用高分子制品股份有限公司 | Disposable use sequential injection device |
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| CN205379469U (en) * | 2016-01-26 | 2016-07-13 | 安徽智博新材料科技有限公司 | Ware is prepared to skin test liquid |
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| CA2786366A1 (en) * | 2010-01-05 | 2011-07-14 | Allergan, Inc. | Syringe comprising two plungers with locking means |
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| US3749084A (en) * | 1971-05-03 | 1973-07-31 | A Cucchiara | Sequentially dispensing syringe with multiple needle assembly |
| CN201418927Y (en) * | 2009-05-15 | 2010-03-10 | 李淑美 | One-tube double-liquid syringe |
| CN203915674U (en) * | 2014-06-26 | 2014-11-05 | 山东威高集团医用高分子制品股份有限公司 | Disposable use sequential injection device |
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