US3557787A - Disposable syringe - Google Patents

Disposable syringe Download PDF

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Publication number
US3557787A
US3557787A US732622A US3557787DA US3557787A US 3557787 A US3557787 A US 3557787A US 732622 A US732622 A US 732622A US 3557787D A US3557787D A US 3557787DA US 3557787 A US3557787 A US 3557787A
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United States
Prior art keywords
tubular member
syringe
inner tubular
forward end
sealing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
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US732622A
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English (en)
Inventor
Milton J Cohen
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Individual
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Individual
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Publication date
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Publication of US3557787A publication Critical patent/US3557787A/en
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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/28—Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle
    • A61M5/284—Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle comprising means for injection of two or more media, e.g. by mixing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31596—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms comprising means for injection of two or more media, e.g. by mixing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A61M5/34—Constructions for connecting the needle, e.g. to syringe nozzle or needle hub
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31596—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms comprising means for injection of two or more media, e.g. by mixing
    • A61M2005/31598—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms comprising means for injection of two or more media, e.g. by mixing having multiple telescopically sliding coaxial pistons encompassing volumes for components to be mixed
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/28—Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle
    • A61M5/285—Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle with sealing means to be broken or opened
    • A61M5/286—Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle with sealing means to be broken or opened upon internal pressure increase, e.g. pierced or burst
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/28—Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle
    • A61M5/285—Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle with sealing means to be broken or opened
    • A61M5/288—Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle with sealing means to be broken or opened by piercing without internal pressure increase

Definitions

  • gh in sealing relaer is formed with a g an injection needle in alignment in use with the inner tubular member.
  • PATENTEU JANZBIQYI SHEET 2 OF 2 DISPOSABLE SYRINGE This invention relates to a device for the administration of parenteral solutions and more particularly to a hypodermic syringe adapted to contain dry solids separate and apart from the dissolving or carrier liquids until, immediately prior to administration, the liquid is caused to flow into the compartment containing the solids for injection of the formed mixture.
  • the most effective means for maintaining the shelf life over extended periods of time is to maintain complete separation between the liquid carrier and the solids to be incorporated therein, until immediately prior to use. Maintenance of solid-liquid separation until time of use presents other problems with respect to ejecting and administering the solution containing the necessary concentration of ingredients and under the most sanitary conditions.
  • the usual practice is to introduce the solids into the liquid for solution in a suitable container from which the solution can be withdrawn into a syringe for injection. This procedure required the use of at least three separate containers and maintenance under sterile conditions as well as accurate measurement of the ingredients.
  • FIG. 1 is a sectional elevational view of the syringe embodying the features of this invention, with the elements illustrated prior to use;
  • FIG. 2 is a sectional elevational view of the syringe shown in FIG. 1 with the syringe partially actuated to effect displacement of the liquid carrier from the liquid chamber to the solids chamber for solution or admixture;
  • FIG. 3 is a sectional elevational view of the syringe shown in FIGS. 1 and 2 with the syringe in fully actuated position to effect displacement of the freshly prepared solution from the solids compartment for injection;
  • FIG. 4 is a sectional elevational view of a portion of the syringe shown in FIGS. 1 to 3 and showing a modification in the closure for the liquid containing compartment;
  • FIG. 5 is a sectional elevational view of the actuator which may also be used as a needle cover.
  • the syringe of this invention is formed with an outer casing l in the form of a tubular member, formed of glass, plastic or the like, having a continuous bore 2 extending therethrough from an open rearward end portion 3 to a neck portion 4 of smaller cross section, at the forward end.
  • the forward end is sealed by means of a disc member 5 held in place in sealing relationship across the open neck 6 of the tubular member I by means of a metal cap 7 which is crimped about the outer neck end portion of the tubular member while the inner portions 8 of the cap overlap the outer edge portions of the sealing disc member overlying the flattened end surface 9 of the tubular member.
  • a hub member II has a skirt portion I2 crimped about the skirt portion of the cap for securing the hub onto the neck end portion of the tubular member.
  • the hub is also formed with an intermediate collapsible or corrugated portion 13 extending forwardly in axial alignment with the forward end of the tubular member with a hub 14 on the forward end through which a hollow needle 15 extends with a sharpened end portion of the needle projecting into the interior of the hub member II for a distance less than the spaced relationship between the hub end and the diaphragm 5, when in normal position, thereby to locate the rearward end of the needle immediately in advance of the center of the diaphragm.
  • a second tubular member 20 of glass, plastic or the like material is dimensioned to have an outer wall to wall dimension which is less than the inner wall to wall dimension of the tubular member I to enable the former to be telescoped through the interior of the outer tubular member 1.
  • the second tubular member is similarly formed with a passage 21 extending from the open rearward end 22 through a neck portion 23 of smaller cross section at the forward end.
  • the forward neck end portion of the second tubular member is fitted with a rubber stopper 24 including an outer ribbed portion 25 fitted in gripping relationship about the neck and extending laterally beyond the walls of the second tubular member for a distance to effect sealing engagement with the inner walls of the outer tubular member 1 whereby the second tubular member is capable of the function of a piston movable axially relative the outer tubular member 1 thereby to provide a piston and cylinder arrangement between the two tubular members.
  • the rubber stopper 25 has a disc portion 26 which normally spans the forward end of the passage to seal the tubular member. It is further formed with one or more openings 27 in the lateral portions beyond the passage to enable flow of liquid from the second tubular member into the firstwhen the sealing disc 26 is flexed for displacement for sealing engagement with the end of the second tubular member. Again, the rearward end portion of the second tubular member is formed with an outwardly extending flanged portion 28 for use as a finger grip, as will hereinafter be described. The rearward end of the passage 21 is sealed with a rubber plug 30 mounted for axial displacement through the passage 21 as a piston within the cylinder defined by the second tubular member.
  • Means such as a threaded stud 31, is provided on the rearward end of the plug type piston for connection of an actuator 32 for displacement of the piston relative the cylinder.
  • the actuator 32 is in the form of a third elongate tubular member dimensioned to have a cross section less than the cross section of the passage 21 through the second tubular member and formed at one end with an internally threaded female portion 33 for threaded engagement onto the threaded plug 31.
  • the rearward end of the actuator is formed with an outwardly extending flanged portion 34, for use as a finger grip.
  • the actuator is capable of use as a needle cover to protect the needle when other than in position of use and which can be removed from the hub to expose the needle and for attachment to the plug for operation of the device, when in position of use.
  • the element supplies the dual function of a needle protector during nonuse and as an actuator in use.
  • fluid 35 is housed in sealing relationship within the second tubular member while the dry medicant is housed in sealing relationship within the first tubular member.
  • the loaded device can be shipped and stored for extended periods of time without deterioration of the ingredients and without exposure of the elements to nonsanitary conditions.
  • Administration is made without change of devices and without exposure of the freshly prepared solution or suspension by inserting the needle into the vessel or tissue.
  • the outer casing is grasped with the one hand with the needle fingers beneath the flanged portion 10.
  • the needle is inserted and the hub is compressed to effect relative movement between the needle and the rubber sealing diaphragm 5 whereby the rearward end of the needle punctures the diaphragm to bring the end of the needle into the chamber 2 for direct communication with the freshly prepared liquid system.
  • the thumb is pressed down onto the actuator which, at the end of its travel in the second tubular member, causes displacement of the second tubular member for movement as a piston through the cylindrical passage 2 of the first tubular member thereby forcibly to displace the freshly prepared liquid system from the interior of the first tubular member through the needle and into the tissue.
  • the entire device can be discarded.
  • the sealing disc 26 extends continuously in sealing engagement across the neck of the second tubular member but is provided with a slit 40 which maintains a sealing relationship until opened in response to the application of fluid pressure as the plug 30 is displaced forwardly through the passage 21.
  • a syringe assembly for injection comprising inner and outer tubular members with the inner members having an outer wall to wall dimension less than the inner wall to wall dimension of the outer tubular member to enable the inner tubular member to be telescoped within the outer tubular member, said inner tubular member defining a planar flange surface on the forward end thereof, a rupturable closure sealing the forward end of the outer tubular member, a.flexible closure having a resilient, thin web means across said flange surface and sealing the forward end of the inner tubular member, said thin web means including passage means therethrough seated on said flange surface in sealing relation thereto whereby said passage means are unseated to communicate with the interior of the inner tubular member in response to internal pressure therein, a piston ring portion on the forward end of the inner tubular member in sliding engagement with the inner walls of the outer tubular member.
  • a piston plug dimensioned slidably to be received within the inner tubular member, and means for actuating the piston plug axially relative to the inner tubular member, a hypodermic needle, and collapsible means on the forward end ortion of the outer tubular member supporting the needle wit the rear ward end terminating a short distance in advance of the rupturable closure when in uncollapsed position and penetrating through the rupturable closure when in collapsed position.
  • a syringe as claimed in claim 1 which includes a removable cover for the needle.
  • a syringe as claimed in claim 1 in which the inner tubular member is adapted to contain a liquid carrier and in which the outer tubular member is adapted to contain a dry material to be taken up by the liquid carrier when the latter is forced from the inner tubular member into the outer tubular member in response to movement of the piston plug axially in the inner tubular member.
  • a syringe as claimed in claim 1 in which the collapsible means comprises a hub member secured at its rearward end portion onto the forward end of the outer tubular member and a forward end having an opening through which the needle extends with a flexible portion between the ends to enable displacement of the forward end between normal and collapsed position.
  • a syringe as claimed in claim 1 in which the piston ring portion on the forward end of the inner tubular member comprises ring members of rubberlike material in sealing engagement with the outer walls of the inner tubular member and extending into sealing engagement with the inner walls of the outer tubular member.
  • a syringe as claimed in claim 1 in which the piston ring portion and flexible closure are of a unitary construction mounted onto the forward end portion of the inner tubular member and in which the means in the flexible sealing closure comprises openings extending through the sealing member in a position offset outwardly from axial alignment with the passage through the inner tubular member.
  • a syringe as claimed in claim 1 which includes means on the rearward end of the piston plug for attachment of an actuator and which includes an elongate actuator dimensioned to exceed the length of travel of the piston plug through the inner tubular member.
  • a syringe as claimed in claim 8 in which the actuator comprises an elongate rod dimensioned to be received in telescoping relation within the inner tubular member and with means for attachment of the actuator to the piston plug.
  • a syringe as claimed in claim 1 which includes flanged members extending radially outwardly from the rearward end portions of the inner and outer tubular members for use as finger grips.

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  • Health & Medical Sciences (AREA)
  • Vascular Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
US732622A 1968-05-28 1968-05-28 Disposable syringe Expired - Lifetime US3557787A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US73262268A 1968-05-28 1968-05-28

Publications (1)

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US3557787A true US3557787A (en) 1971-01-26

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US732622A Expired - Lifetime US3557787A (en) 1968-05-28 1968-05-28 Disposable syringe

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US (1) US3557787A (enrdf_load_stackoverflow)
JP (1) JPS51398B1 (enrdf_load_stackoverflow)
BE (1) BE733744A (enrdf_load_stackoverflow)
CH (1) CH489248A (enrdf_load_stackoverflow)
DE (1) DE1965990A1 (enrdf_load_stackoverflow)
FR (1) FR2011003B1 (enrdf_load_stackoverflow)
GB (1) GB1263949A (enrdf_load_stackoverflow)
IL (1) IL32209A (enrdf_load_stackoverflow)
SE (1) SE364185B (enrdf_load_stackoverflow)

Cited By (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3678931A (en) * 1970-06-09 1972-07-25 Milton J Cohen Syringe
US3687296A (en) * 1971-03-26 1972-08-29 Ewi Research & Dev Corp Fluid separator
US3718139A (en) * 1970-08-21 1973-02-27 G Hanford Syringe
US3757779A (en) * 1971-05-24 1973-09-11 Century Labor Inc Filter syringe
US3807119A (en) * 1972-06-21 1974-04-30 W Shields Method of assembling a multiple compartment hypodermic syringe
US4116240A (en) * 1977-03-11 1978-09-26 Guiney Aeneas C Mixing syringe
US4303069A (en) * 1978-10-30 1981-12-01 Cohen Milton J Hypodermic syringe with needle guide
US4405317A (en) * 1981-09-30 1983-09-20 The West Company Syringe assembly
US4425122A (en) 1981-11-09 1984-01-10 Cohen Milton J Parenteral apparatus
US4781701A (en) * 1986-07-11 1988-11-01 Arzneimittel Gmbh Apotheker Vetter & Co. Ravensburg Syringe for medical purposes
US5156598A (en) * 1988-12-06 1992-10-20 C. R. Bard, Inc. Prefilled syringe delivery system
US5429603A (en) * 1990-12-04 1995-07-04 Medinject A/S Two-compartment syringe assembly and a method of producing a two-compartment syringe assembly
US5662472A (en) * 1995-08-18 1997-09-02 Dentsply Gmbh Hue and lightness identification system for dental products
US20030026849A1 (en) * 1997-10-15 2003-02-06 Thomas Jefferson University Nitric oxide donor compositions, methods, apparatus, and kits for preventing or alleviating vasoconstriction or vasospasm in a mammal
US6726005B2 (en) 2001-09-13 2004-04-27 Kerr Corporation Dental capsule
EP1039946A4 (en) * 1997-12-19 2004-07-21 United States Surgical Corp FIBRIN MIXTURE AND DISPENSER ASSEMBLY
US20050090781A1 (en) * 2001-12-13 2005-04-28 Tokumi Baba Administration instrument for medical use
US6942639B2 (en) 1996-04-30 2005-09-13 Medtronic, Inc. Autologous platelet gel delivery system
WO2006128915A1 (de) * 2005-06-02 2006-12-07 Schwoebel Eckhard Mehrzylinderspritze
US20080000835A1 (en) * 2005-05-17 2008-01-03 Fresenius Medical Care North America Hemodialysis methods and apparatus
US20080058732A1 (en) * 2006-08-30 2008-03-06 Arthur Harris Continuous Feed Hypodermic Syringe with Self Contained Cartridge Dispenser
US20090026123A1 (en) * 1996-04-30 2009-01-29 Dolecek Victor D System for the production of autologus platelet gel useful for the delivery of medicinal and genetic agents
US20100310426A1 (en) * 2007-09-06 2010-12-09 Siemens Healthcare Diagnostics Inc. Reagent cartridge
EP2311513A1 (en) * 2009-10-16 2011-04-20 Sanofi-Aventis Deutschland GmbH Cartridge holder assembly for a drug delivery device
EP2173401A4 (en) * 2007-07-27 2012-03-21 Fresenius Med Care Hldg Inc Systems and methods for delivery of peritoneal dialysis (pd) solutions
CN102641145A (zh) * 2011-02-21 2012-08-22 三井化学株式会社 3成分混合装置及3成分混合试剂盒
US20120258422A1 (en) * 2011-04-11 2012-10-11 Voco Gmbh Mixing and application capsule for producing a dental preparation
US8328784B2 (en) 2005-01-28 2012-12-11 Fresenius Medical Care Holdings, Inc. Systems and methods for delivery of peritoneal dialysis (PD) solutions
CN104023770A (zh) * 2011-12-22 2014-09-03 B.布劳恩梅尔松根公司 多腔混合容器
US20150065991A1 (en) * 2012-04-09 2015-03-05 Becton, Dickinson And Company Vial dosing systems and methods
CN105377327A (zh) * 2013-03-22 2016-03-02 安姆根有限公司 注射器及装配方法
CN105366172A (zh) * 2015-09-25 2016-03-02 （株）沃卓皮肤科技 面膜套装
US20160296704A1 (en) * 2013-10-24 2016-10-13 Amgen Inc. Injector and method of assembly
US9585810B2 (en) 2010-10-14 2017-03-07 Fresenius Medical Care Holdings, Inc. Systems and methods for delivery of peritoneal dialysis (PD) solutions with integrated inter-chamber diffuser
WO2017083622A1 (en) * 2015-11-13 2017-05-18 Bayer Healthcare Llc Nested syringe assembly
WO2017089272A1 (en) * 2015-11-27 2017-06-01 Sanofi-Aventis Deutschland Gmbh Medicament delivery device
USD807502S1 (en) 2015-03-02 2018-01-09 Neomed, Inc. Enteral syringe
US9987428B2 (en) 2011-10-14 2018-06-05 Amgen Inc. Injector and method of assembly
USD831203S1 (en) 2015-03-02 2018-10-16 Neomed, Inc. Enteral syringe
USD831204S1 (en) 2015-03-02 2018-10-16 Neomed, Inc. Enteral syringe
US10307337B2 (en) 2015-03-24 2019-06-04 Neomed, Inc. Oral administration coupler for back-of-mouth delivery
US10369228B2 (en) 2009-03-26 2019-08-06 Jeffrey E. Thomas Method and composition for alleviating or preventing ischemic tissue damage
US10420709B2 (en) 2015-07-14 2019-09-24 Neomed, Inc. Dosing control coupling for enteral fluid transfer
US10682287B2 (en) 2015-07-14 2020-06-16 Neomed, Inc. Dosing control coupling for enteral fluid transfer and enteral couplings and syringes

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JPS4977487A (enrdf_load_stackoverflow) * 1972-11-29 1974-07-25
FR2528706A1 (fr) * 1982-06-18 1983-12-23 Dessapt Bernard Seringue perfectionnee a double compartiment
JPS6327908U (enrdf_load_stackoverflow) * 1986-08-06 1988-02-24
DE3704453A1 (de) * 1987-02-13 1988-08-25 Anita Schumacher Doppelkolbeninjektionsspritze (mit mischkanal)
GB2229374B (en) * 1989-02-17 1993-04-21 Bespak Plc Improvements in or relating to dispensing apparatus
DE9400867U1 (de) * 1994-01-17 1994-03-03 Christian Dunkel Gmbh Werkzeugbau, 12459 Berlin Einwegspritze mit Spritzampulle
JP5843870B2 (ja) * 2010-10-01 2016-01-13 サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング 解除機構を備えたニードルアセンブリ
US20160296703A1 (en) * 2013-11-05 2016-10-13 3P Innovation Limited A Pharmaceutical Component-Mixing Delivery Assembly

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US2591706A (en) * 1950-09-29 1952-04-08 Compule Corp Plural-compartment admixing hypodermic syringe ampoule for segregated storage of ingredients of liquid medicinal solutions and therapeutic preparations
US2675804A (en) * 1949-07-09 1954-04-20 Becton Dickinson Co Syringe
US2699167A (en) * 1952-04-25 1955-01-11 Paul A Raiche Hypodermic injector
US2869543A (en) * 1957-08-23 1959-01-20 Iowa Cooperative Ass Injector
US3108591A (en) * 1962-05-29 1963-10-29 Bristol Mycrs Company Syringe
US3303846A (en) * 1963-10-08 1967-02-14 Functional Container Corp Mixing syringe having separate compartments for incompatible medicaments
US3342180A (en) * 1964-04-24 1967-09-19 American Cyanamid Co Disposable liquid-powder package and hypodermic syringe
US3413974A (en) * 1963-06-26 1968-12-03 Milton J. Cohen Hypodermic syringes

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Publication number Priority date Publication date Assignee Title
US2675804A (en) * 1949-07-09 1954-04-20 Becton Dickinson Co Syringe
US2591706A (en) * 1950-09-29 1952-04-08 Compule Corp Plural-compartment admixing hypodermic syringe ampoule for segregated storage of ingredients of liquid medicinal solutions and therapeutic preparations
US2699167A (en) * 1952-04-25 1955-01-11 Paul A Raiche Hypodermic injector
US2869543A (en) * 1957-08-23 1959-01-20 Iowa Cooperative Ass Injector
US3108591A (en) * 1962-05-29 1963-10-29 Bristol Mycrs Company Syringe
US3413974A (en) * 1963-06-26 1968-12-03 Milton J. Cohen Hypodermic syringes
US3303846A (en) * 1963-10-08 1967-02-14 Functional Container Corp Mixing syringe having separate compartments for incompatible medicaments
US3342180A (en) * 1964-04-24 1967-09-19 American Cyanamid Co Disposable liquid-powder package and hypodermic syringe

Cited By (91)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3678931A (en) * 1970-06-09 1972-07-25 Milton J Cohen Syringe
US3718139A (en) * 1970-08-21 1973-02-27 G Hanford Syringe
US3687296A (en) * 1971-03-26 1972-08-29 Ewi Research & Dev Corp Fluid separator
US3757779A (en) * 1971-05-24 1973-09-11 Century Labor Inc Filter syringe
US3807119A (en) * 1972-06-21 1974-04-30 W Shields Method of assembling a multiple compartment hypodermic syringe
US4116240A (en) * 1977-03-11 1978-09-26 Guiney Aeneas C Mixing syringe
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Also Published As

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CH489248A (de) 1970-04-30
DE1965990A1 (de) 1971-02-11
FR2011003A1 (enrdf_load_stackoverflow) 1970-02-27
SE364185B (enrdf_load_stackoverflow) 1974-02-18
BE733744A (enrdf_load_stackoverflow) 1969-11-03
JPS51398B1 (enrdf_load_stackoverflow) 1976-01-07
IL32209A (en) 1972-07-26
GB1263949A (en) 1972-02-16
DE1926387A1 (de) 1969-12-11
IL32209A0 (en) 1969-07-30
FR2011003B1 (enrdf_load_stackoverflow) 1974-06-14

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