US3718139A - Syringe - Google Patents

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Publication number
US3718139A
US3718139A US00065842A US3718139DA US3718139A US 3718139 A US3718139 A US 3718139A US 00065842 A US00065842 A US 00065842A US 3718139D A US3718139D A US 3718139DA US 3718139 A US3718139 A US 3718139A
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sleeve
plunger
bore
open
cylindrical bore
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US00065842A
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G Hanford
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/315Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31596Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms comprising means for injection of two or more media, e.g. by mixing
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/315Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31596Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms comprising means for injection of two or more media, e.g. by mixing
    • A61M2005/31598Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms comprising means for injection of two or more media, e.g. by mixing having multiple telescopically sliding coaxial pistons encompassing volumes for components to be mixed
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/28Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle
    • A61M5/285Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle with sealing means to be broken or opened

Definitions

  • This invention relates to a syringe type medicament applicator containing a solution and a dry medicament adapted for mixing just prior to application.
  • the applicator syringe of this invention comprises three components economically produced by moulding from plastic material.
  • the barrel of the syringe is adapted to contain the solution.
  • a sleeve is slidably mounted in the barrel and is closed at its inner end with a severable disk integral closure.
  • a plunger is slidably mounted in the sleeve and is formed at its inner end with an annular recess, to receive a medicament tablet.
  • An actuating stem is formed integral with the plunger and extends through the sleeve and outwardly a short distance from the outer end of the sleeve.
  • the recess has an oval cutting edge slidable along the sleeve wall for severing the disk on initial inward movement of the plunger to expose the solid medicament to the solution. Thereafter, the plunger and sleeve are moved in unison axially of the barrel for ejecting the mixture therefrom.
  • the oval cutting edge engages the peripheral portion of the closure progressively to sever the same with a minimum of axial pressure on the plunger stem. Friction from the close fit of the plunger stem in the sleeve tends to prevent relative movement to effect severance of the closure except on positive pressure greater than would occur in the ordinary handling of the loaded syringe, or resulting from the syringe being dropped.
  • FIG. 1 is a lengthwise, sectional view of the syringe embodying my invention, the syringe being illustrated as loaded with the solution and dry medicament for shipment;
  • FIG. 2 is a view, similar to FIG. 1, showing the plunger initially moved inwardly, effecting severance of the closure from the inner end of the sleeve, and
  • FIG. 3 is a side elevational view of the plunger partly in section in assembly relation to the sleeve.
  • the syringe barrel is shown with a sleeve 12 slidably disposed in the bore 14 of the barrel 10.
  • the sleeve is formed at its inner end with an integral closure 16.
  • the closure 16 at the joinder of its periphery with the sleeve bore 18, is of reduced thickness, as indicated at to facilitate severance.
  • a plunger 22 is slidable in the bore 18 of the sleeve 12, and has an actuating stem 24, cruciform in cross section.
  • the inner end portion 25 of the plunger 22 is formed with an annular recess 26, the outer portion of which is beveled as at 28 to provide an oval or elliptical knife edge 30 inclined to the axis of the plunger.
  • the internal bore 18 of the sleeve 12 adjacent the closure 16 makes a relatively close fit as at 23 with the inner end portion 25 of the plunger for a sufiicient 6 distance back from the end closure to frictionally resist movement of the plunger prior to the approach of the cutting edge 30 with the closure 16.
  • the sleeve bore may be of slightly increased diameter and have a shallow relief groove such as 21, whereby insertion of the plunger will be relatively free and unable to trap air in front thereof to prevent the closure from being blown from the sleeve end upon insertion of the plunger.
  • the end closure is easily cut free, subject to overcoming the frictional resistance.
  • the closed end of the barrel 10 is formed with a neck portion 36 having a discharge passageway 38 closed by an integral finger grip portion 40, which is joined to the neck 36 by a side wall having an annular groove 42 to facilitate breaking away the grip portion to expose the passageway 38, after which a canula as at 44 may be applied.
  • the three components of the syringe are sterilized, and a quantity of solution, indicated at 50, which may be sterile water, is placed in the barrel 10.
  • a quantity of solution indicated at 50, which may be sterile water
  • the sleeve 12 is then inserted a short distance in the barrel 10.
  • a dry medicament 52 which may be in the form of a pill, is placed in the recess 26 of the plunger 22, and the plunger then inserted in the sleeve 12, with the knife edge 21 of the plunger in proximity to the sleeve end closure 12 where frictional resistance to further movement is felt.
  • the syringe is now loaded with the solution, and the solid medicament, and may be shipped in this condition.
  • the sleeve 12 is grasped between the fingers, and the stem 24 moved inwardly against the frictional resistance.
  • This initial inward movement of the stem 24 and plunger 22 moves the oval knife edge 30 thereof progressively against the reduced thickness of the closure periphery 20, effecting severance of the closure from the sleeve 12.
  • the syringe barrel 10 is grasped between the fingers, and the sleeve 12, together with plunger 22, are moved inwardly as a unit, forcing the mixture through the discharge passage 38, and the canula 44, which has been applied after breaking away the tip 40.
  • the stem 24 may be formed with a circular flange 32 for limiting inward movement of the plunger in sleeve 12, as shown in FIG. 2. It may so limit the movement as to prevent the knife from cutting the closure completely from the sleeve if desired.
  • a medicament applicator of the syringe type comprising:
  • a tubular body having an internal cylindrical bore of uniform cross section with one end open and the other end having a neck portion with a sealed discharge passageway;
  • said sleeve having an internal cylindrical bore open at one end and closed at the other end with a circular disk having an annular groove reducing the thickness of said disk at the juncture thereof with said other end of the sleeve bore, said sleeve bore including a portion of reduced diameter for a relatively small portion of its length adjacent said other end and a longitudinal groove extending from said reduced diameter portion to said one end;
  • a plunger of cylindrical cross section for a relativeinto said portion of said plunger, said recess being fully closed except at said open end;

Abstract

A medicament applicator of the syringe type having a plunger sleeve slidable in the syringe barrel, the inner end of which has an integral severable circular closure, and a plunger slidably mounted in the sleeve and recessed to contain a solid medicament, the recess having an oval cutting edge to shear the closure from the plunger sleeve upon initial inward movement of the plunger, to expose the solid medicament to a solution container in the syringe barrel, whereupon further inward movement of the sleeve and plunger, the mixture is ejected.

Description

Unite tates ae t Hartford 1 Feb. 27, 1973 1 1 SYRINGE 3,354,883 11/1967 Southerland ..l28/272 x [76] Inventor: George W. Haniord, 304 Oneida St.,
Syracuse 13202 Primary Examiner-Richard A. Gaudet Assistant Examiner--J. Yasko [22] Flledz Aug. 21, 1970 Atmmey F Keiper [21] App]. No.: 65,842
. [57 ABSTRACT [52] US. Cl. ..l28/235, 128/218 M A icament applicator of the syringe type having a [51] Int. Cl. ..A6lm 1/00 Plunger Sleave slidable in the Syringe barrel, the inner [58] Field of Search ..l28/218, 217, 216, 215, 214, end of which has an integral severable circular clo- 128/213, 235, 234, 260, 264, 265, 272, 218 sure, and a plunger slidably mounted in the sleeve and D, 220 recessed to contain a solid medicament, the recess having an oval cutting edge to shear the closure from References Cited the plunger sleeve upon initial inward movement of the plunger, to expose the solid medicament to a solu- UNITED STATES PATENTS tion container in the syringe barrel, whereupon further 2,317,558 4/1943 Smith ..128/218 inward movement of the sleeve and plunger, the mix- 2,s41,145 7/1958 Epps ..128/218 ture is ejected. 3,557,787 1/1971 Cohen.. ..l28/2l8 3,477,432 11/1969 Shaw ..l28/2l8 3 Claims, 3 Drawing Figures SYRINGE This invention relates to a syringe type medicament applicator containing a solution and a dry medicament adapted for mixing just prior to application.
The applicator syringe of this invention comprises three components economically produced by moulding from plastic material. The barrel of the syringe is adapted to contain the solution. A sleeve is slidably mounted in the barrel and is closed at its inner end with a severable disk integral closure. A plunger is slidably mounted in the sleeve and is formed at its inner end with an annular recess, to receive a medicament tablet. An actuating stem is formed integral with the plunger and extends through the sleeve and outwardly a short distance from the outer end of the sleeve. The recess has an oval cutting edge slidable along the sleeve wall for severing the disk on initial inward movement of the plunger to expose the solid medicament to the solution. Thereafter, the plunger and sleeve are moved in unison axially of the barrel for ejecting the mixture therefrom. The oval cutting edge engages the peripheral portion of the closure progressively to sever the same with a minimum of axial pressure on the plunger stem. Friction from the close fit of the plunger stem in the sleeve tends to prevent relative movement to effect severance of the closure except on positive pressure greater than would occur in the ordinary handling of the loaded syringe, or resulting from the syringe being dropped.
The above and other novel features of the invention will appear more fully hereinafter from the following detailed description when taken in conjunction with the accompanying drawings. It is expressly understood that the drawings are employed for purposes of illustration only and are not designed as a definition of the limits of the invention, reference being had for this purpose to the appended claims.
In the drawings wherein like reference numerals indicate like parts:
FIG. 1 is a lengthwise, sectional view of the syringe embodying my invention, the syringe being illustrated as loaded with the solution and dry medicament for shipment;
FIG. 2 is a view, similar to FIG. 1, showing the plunger initially moved inwardly, effecting severance of the closure from the inner end of the sleeve, and
FIG. 3 is a side elevational view of the plunger partly in section in assembly relation to the sleeve.
Referring to the drawings the syringe barrel is shown with a sleeve 12 slidably disposed in the bore 14 of the barrel 10. The sleeve is formed at its inner end with an integral closure 16. The closure 16, at the joinder of its periphery with the sleeve bore 18, is of reduced thickness, as indicated at to facilitate severance.
A plunger 22 is slidable in the bore 18 of the sleeve 12, and has an actuating stem 24, cruciform in cross section. The inner end portion 25 of the plunger 22 is formed with an annular recess 26, the outer portion of which is beveled as at 28 to provide an oval or elliptical knife edge 30 inclined to the axis of the plunger.
The internal bore 18 of the sleeve 12 adjacent the closure 16 makes a relatively close fit as at 23 with the inner end portion 25 of the plunger for a sufiicient 6 distance back from the end closure to frictionally resist movement of the plunger prior to the approach of the cutting edge 30 with the closure 16. Rearward of the close fit 23, the sleeve bore may be of slightly increased diameter and have a shallow relief groove such as 21, whereby insertion of the plunger will be relatively free and unable to trap air in front thereof to prevent the closure from being blown from the sleeve end upon insertion of the plunger. Thus the end closure is easily cut free, subject to overcoming the frictional resistance.
The closed end of the barrel 10 is formed with a neck portion 36 having a discharge passageway 38 closed by an integral finger grip portion 40, which is joined to the neck 36 by a side wall having an annular groove 42 to facilitate breaking away the grip portion to expose the passageway 38, after which a canula as at 44 may be applied.
The three components of the syringe are sterilized, and a quantity of solution, indicated at 50, which may be sterile water, is placed in the barrel 10. The sleeve 12 is then inserted a short distance in the barrel 10. A dry medicament 52, which may be in the form of a pill, is placed in the recess 26 of the plunger 22, and the plunger then inserted in the sleeve 12, with the knife edge 21 of the plunger in proximity to the sleeve end closure 12 where frictional resistance to further movement is felt. The syringe is now loaded with the solution, and the solid medicament, and may be shipped in this condition.
In use, the sleeve 12 is grasped between the fingers, and the stem 24 moved inwardly against the frictional resistance. This initial inward movement of the stem 24 and plunger 22 moves the oval knife edge 30 thereof progressively against the reduced thickness of the closure periphery 20, effecting severance of the closure from the sleeve 12. This exposes the solid medicament or pill 52, to the liquid 50, in which it dissolves. Thereafter, the syringe barrel 10 is grasped between the fingers, and the sleeve 12, together with plunger 22, are moved inwardly as a unit, forcing the mixture through the discharge passage 38, and the canula 44, which has been applied after breaking away the tip 40. The stem 24 may be formed with a circular flange 32 for limiting inward movement of the plunger in sleeve 12, as shown in FIG. 2. It may so limit the movement as to prevent the knife from cutting the closure completely from the sleeve if desired.
While a single form of the invention has been illustrated and described, it is to be understood that the invention is not limited thereto. As various changes in the construction and arrangement may be made without departing from the spirit of the invention, as will be apparent to those skilled in the art, reference will be had to the appended claims for a definition of the limits of the invention.
What is claimed is:
l. A medicament applicator of the syringe type comprising:
a. a tubular body having an internal cylindrical bore of uniform cross section with one end open and the other end having a neck portion with a sealed discharge passageway;
b. a tubular sleeve having an outer diameter at one end slidable in sealed relation within the cylindrical bore of said body;
c. said sleeve having an internal cylindrical bore open at one end and closed at the other end with a circular disk having an annular groove reducing the thickness of said disk at the juncture thereof with said other end of the sleeve bore, said sleeve bore including a portion of reduced diameter for a relatively small portion of its length adjacent said other end and a longitudinal groove extending from said reduced diameter portion to said one end;
. a plunger of cylindrical cross section for a relativeinto said portion of said plunger, said recess being fully closed except at said open end;
. the relative lengths of said body, sleeve and adjacent said other end of said body upon full insertion of said sleeve into said body.
1 ll portion f i l h at one end i 2. The invention according to claim 1 wherein said tion having an outer diameter slidable in sealed 1O plfmger of cfuclfol'm cross Sectlon along other than relation within the cylindrical bore of said sleeve 531d P Oflts lengthand in tight f i i l engagement with said 3. The invention according to claim I wherein said do f reduced diameter; sharp terminal edge oval in shape, said plunger being terminated in a plane not normal to the axis thereof.
. internal walls defining a recess extending from an open end defined by a sharp terminal edge axially

Claims (3)

1. A medicament applicator of the syringe type comprising: a. a tubular body having an internal cylindrical bore of uniform cross section with one end open and the other end having a neck portion with a sealed discharge passageway; b. a tubular sleeve having an outer diameter at one end slidable in sealed relation within the cylindrical bore of said body; c. said sleeve having an internal cylindrical bore open at one end and closed at the other end with a circular disk having an annular groove reducing the thickness of said disk at the juncture thereof with said other end of the sleeve bore, said sleeve bore including a portion of reduced diameter for a relatively small portion of its length adjacent said other end and a longitudinal groove extending from said reduced diameter portion to said one end; d. a plunger of cylindrical cross section for a relatively small portion of its length at one end, said portion having an outer diameter slidable in sealed relation within the cylindrical bore of said sleeve and in tight frictional engagement with said portion of reduced diameter; e. internal walls defining a recess extending from an open end defined by a sharp terminal edge axially into said portion of said plunger, said recess being fully closed except at said open end; f. the relative lengths of said body, sleeve and plunger being such that said disk is severed at said annular groove upon full insertion of said plunger into said sleeve, and said other end of said sleeve is adjacent said other end of said body upon full insertion of said sleeve into said body.
2. The invention according to claim 1 wherein said plunger is of cruciform cross section along other than said portion of its length.
3. The invention according to claim 1 wherein said sharp terminal edge is oval in shape, said plunger being terminated in a plane not normal to the axis thereof.
US00065842A 1970-08-21 1970-08-21 Syringe Expired - Lifetime US3718139A (en)

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Cited By (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0071289A1 (en) * 1981-07-27 1983-02-09 Duphar International Research B.V Automatic injection syringe
US4405317A (en) * 1981-09-30 1983-09-20 The West Company Syringe assembly
US5015101A (en) * 1986-03-21 1991-05-14 Klaus Draenert Apparatus and process for mixing and filling
US5320845A (en) * 1993-01-06 1994-06-14 Py Daniel C Apparatus for delivering multiple medicaments to an eye without premixing in the apparatus
US5613957A (en) * 1991-12-02 1997-03-25 Daniel Py Apparatus for applying medicament to an eye
USRE37047E1 (en) 1992-04-06 2001-02-06 Daniel Py Cartridge for applying medicament to an eye from a dispenser
US20040215148A1 (en) * 2003-04-22 2004-10-28 Becton, Dickinson And Company Syringe tip cap
WO2011035449A3 (en) * 2009-09-22 2011-05-26 Medmix System Ag Sealed container comprising a displaceable piston
WO2012104376A1 (en) * 2011-02-02 2012-08-09 Bioneer A/S A syringe
US20130116627A1 (en) * 2010-07-15 2013-05-09 Jochen Heinz Syringe Having Reduced Static Friction
JP2015521509A (en) * 2012-06-26 2015-07-30 バイオニア・アクティーゼルスカブBioneer A/S Syringe with hollow plunger
US20170312449A1 (en) * 2014-10-21 2017-11-02 Sulzer Mixpac Ag Dual-chamber syringe
US10786433B2 (en) * 2017-09-13 2020-09-29 William J Moore Buffering agent cartridge
US11260177B1 (en) * 2014-03-18 2022-03-01 Yasser Sadek Dental anesthetic buffer system

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2317558A (en) * 1941-03-24 1943-04-27 Arthur E Smith Hypodermic syringe construction
US2841145A (en) * 1956-05-07 1958-07-01 John A Epps Syringe
US3354883A (en) * 1965-03-08 1967-11-28 Southerland Elizabeth Lee Disposable syringe having frangible means for mixing plural medicaments
US3477432A (en) * 1964-07-21 1969-11-11 Joseph Denman Shaw Combination mixing and injecting medical syringe
US3557787A (en) * 1968-05-28 1971-01-26 Milton J Cohen Disposable syringe

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2317558A (en) * 1941-03-24 1943-04-27 Arthur E Smith Hypodermic syringe construction
US2841145A (en) * 1956-05-07 1958-07-01 John A Epps Syringe
US3477432A (en) * 1964-07-21 1969-11-11 Joseph Denman Shaw Combination mixing and injecting medical syringe
US3354883A (en) * 1965-03-08 1967-11-28 Southerland Elizabeth Lee Disposable syringe having frangible means for mixing plural medicaments
US3557787A (en) * 1968-05-28 1971-01-26 Milton J Cohen Disposable syringe

Cited By (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0071289A1 (en) * 1981-07-27 1983-02-09 Duphar International Research B.V Automatic injection syringe
US4405317A (en) * 1981-09-30 1983-09-20 The West Company Syringe assembly
US5015101A (en) * 1986-03-21 1991-05-14 Klaus Draenert Apparatus and process for mixing and filling
US5613957A (en) * 1991-12-02 1997-03-25 Daniel Py Apparatus for applying medicament to an eye
US5685869A (en) * 1991-12-02 1997-11-11 Daniel Py Apparatus for applying medicament to an eye
US5944702A (en) * 1991-12-02 1999-08-31 Instill & Co. Method for instilling a predetermined volume of medicament into an eye
USRE37047E1 (en) 1992-04-06 2001-02-06 Daniel Py Cartridge for applying medicament to an eye from a dispenser
US5320845A (en) * 1993-01-06 1994-06-14 Py Daniel C Apparatus for delivering multiple medicaments to an eye without premixing in the apparatus
US20040215148A1 (en) * 2003-04-22 2004-10-28 Becton, Dickinson And Company Syringe tip cap
US10980944B2 (en) 2003-04-22 2021-04-20 Becton, Dickinson And Company Syringe tip cap
US9415168B2 (en) * 2003-04-22 2016-08-16 Becton, Dickinson And Company Syringe tip cap
WO2011035449A3 (en) * 2009-09-22 2011-05-26 Medmix System Ag Sealed container comprising a displaceable piston
US20130116627A1 (en) * 2010-07-15 2013-05-09 Jochen Heinz Syringe Having Reduced Static Friction
US9220844B2 (en) * 2010-07-15 2015-12-29 Transcodent GmbH & Co. KG Syringe having reduced static friction
KR20140023897A (en) * 2011-02-02 2014-02-27 바이오니어 에이/에스 A syringe
US20140236121A1 (en) * 2011-02-02 2014-08-21 Bioneer A/S Syringe
JP2014507216A (en) * 2011-02-02 2014-03-27 バイオニア・アクティーゼルスカブ Syringe
US9937295B2 (en) * 2011-02-02 2018-04-10 Bioneer A/S Syringe for mixing and ejecting an active pharmaceutical ingredient
WO2012104376A1 (en) * 2011-02-02 2012-08-09 Bioneer A/S A syringe
JP2015521509A (en) * 2012-06-26 2015-07-30 バイオニア・アクティーゼルスカブBioneer A/S Syringe with hollow plunger
US9795745B2 (en) 2012-06-26 2017-10-24 Bioneer A/S Syringe with a hollow plunger
US11260177B1 (en) * 2014-03-18 2022-03-01 Yasser Sadek Dental anesthetic buffer system
US20170312449A1 (en) * 2014-10-21 2017-11-02 Sulzer Mixpac Ag Dual-chamber syringe
US10695505B2 (en) * 2014-10-21 2020-06-30 Sulzer Mixpac Ag Dual-chamber syringe
US10786433B2 (en) * 2017-09-13 2020-09-29 William J Moore Buffering agent cartridge
US11241364B2 (en) * 2017-09-13 2022-02-08 William J Moore Buffering agent cartridge

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