US3451393A - Automatic infusion device - Google Patents

Automatic infusion device Download PDF

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Publication number
US3451393A
US3451393A US525399A US3451393DA US3451393A US 3451393 A US3451393 A US 3451393A US 525399 A US525399 A US 525399A US 3451393D A US3451393D A US 3451393DA US 3451393 A US3451393 A US 3451393A
Authority
US
United States
Prior art keywords
cartridge
barrel
diluent
infusion device
stopper
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
US525399A
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English (en)
Inventor
Stanley J Sarnoff
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Application granted granted Critical
Publication of US3451393A publication Critical patent/US3451393A/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A61M5/145—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons

Definitions

  • FIG. 2 is a perspective view of the casing and its contents with the diluent from a first barrel of the device forced into admixture with the medicament in the second barrel;
  • the first barrel 16 is comprised of an outer cylinder 36, preferably of transparent glass or plastic, shouldered intermediate its ends as indicated at 38 and the inner cartridge 18 is seated against the shoulder and comprises a transparent wall 40, the cartridge containing the diluent 20 being normally retained in the cartridge by a piston 42 at one end of the cartridge and a stopper 44 at the other end thereof.
  • the stopper is provided with a thin diaphragm 46 which, when the piston 42 is operated, exerts a pressure on the diluent and which in turn causes the diluent to transmit a pressure to the diaphragm, thereby distending and finally bursting it.
  • a flow rate restriction element in the line leading to the drop meter as between the flow regulator and the drop meter there is interposed a flow rate restriction element.
  • the element is shown in a most simple form. 'It comprises a nipple 92 with intermediate external flange 94 to enable hose sections to be attached to the nipple, the orifice 96 through the nipple being of a size predetermined in accordance with the medicament to be administered and the maximum rate of flow which could be tolerated by the patient. It is obvious that other permanent forms of orifice restrictive devices may be used as by molding a restriction in the tubing.

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Anesthesiology (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Vascular Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
US525399A 1966-02-07 1966-02-07 Automatic infusion device Expired - Lifetime US3451393A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US52539966A 1966-02-07 1966-02-07

Publications (1)

Publication Number Publication Date
US3451393A true US3451393A (en) 1969-06-24

Family

ID=24093094

Family Applications (1)

Application Number Title Priority Date Filing Date
US525399A Expired - Lifetime US3451393A (en) 1966-02-07 1966-02-07 Automatic infusion device

Country Status (9)

Country Link
US (1) US3451393A (en)van)
BE (1) BE693765A (en)van)
CH (1) CH473591A (en)van)
DE (1) DE1566649A1 (en)van)
FR (1) FR1510549A (en)van)
GB (1) GB1114238A (en)van)
IL (1) IL27371A (en)van)
NL (1) NL6701783A (en)van)
SE (1) SE337449B (en)van)

Cited By (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3595232A (en) * 1968-08-19 1971-07-27 Saul Leibinsohn Nongravitational infusion assembly
US3888239A (en) * 1974-06-21 1975-06-10 Morton K Rubinstein Fluid injection system
US3895631A (en) * 1974-02-04 1975-07-22 Alza Corp Liquid infusion unit
US4065230A (en) * 1975-01-17 1977-12-27 Hart Associates, Inc. Reciprocating infusion pump and directional adapter set for use therewith
EP0014006A3 (en) * 1979-01-25 1980-09-17 Survival Technology, Inc. Automatic, plural spring actuated, injecting device
US4267836A (en) * 1976-11-12 1981-05-19 Whitney Douglass G Injection device and method
US4381006A (en) * 1980-11-10 1983-04-26 Abbott Laboratories Continuous low flow rate fluid dispenser
US4382753A (en) * 1979-03-09 1983-05-10 Avi, Inc. Nonpulsating IV pump and disposable pump chamber
US4391600A (en) * 1979-03-09 1983-07-05 Avi, Inc. Nonpulsating IV pump and disposable pump chamber
US4410322A (en) * 1979-03-09 1983-10-18 Avi, Inc. Nonpulsating TV pump and disposable pump chamber
WO1986006967A1 (en) * 1985-05-20 1986-12-04 Survival Technology, Inc. Automatic medicament ingredient mixing and injecting apparatus
US4666430A (en) * 1984-12-05 1987-05-19 I-Flow Corporation Infusion pump
US4857048A (en) * 1987-05-29 1989-08-15 Hewlett-Packard Company IV pump and disposable flow chamber with flow control
US4997420A (en) * 1989-12-28 1991-03-05 Lefevre Robert J Portable drug delivery device including pump with tapered barrel
US5100389A (en) * 1988-06-21 1992-03-31 Vaillancourt Vincent L Ambulatory infusion pump
US5318539A (en) * 1986-10-17 1994-06-07 Alexander G. B. O'Neil Liquid feeding apparatus utilizing capillary tubing, and syringe driver
US5320503A (en) * 1988-05-17 1994-06-14 Patient Solutions Inc. Infusion device with disposable elements
US5584667A (en) * 1988-05-17 1996-12-17 Davis; David L. Method of providing uniform flow from an infusion device
US5803712A (en) * 1988-05-17 1998-09-08 Patient Solutions, Inc. Method of measuring an occlusion in an infusion device with disposable elements
US5911716A (en) * 1992-01-24 1999-06-15 I-Flow Corporation Platen pump
EP0836505A4 (en) * 1995-06-06 2000-01-12 Science Inc MEDICINE DISPENSER
US6234795B1 (en) * 2000-01-21 2001-05-22 Ultradent Products, Inc. Flexible mixer extender
US6241125B1 (en) * 1996-10-24 2001-06-05 Kenneth H. Jacobsen System and kit accessories for dispensing reactive two component materials
US6251098B1 (en) 1992-01-24 2001-06-26 I-Flow, Corp. Fluid container for use with platen pump
US6358239B1 (en) 1992-01-24 2002-03-19 I-Flow Corporation Platen pump
EP1475114A3 (en) * 1994-09-02 2004-11-24 Societe De Conseils De Recherches Et D'applications Scientifiques S.A.S. Injection system suitable for the administration of semisolid, sustained-release pharmaceutical compositions of gelable peptide salts
US20070105433A1 (en) * 2005-11-07 2007-05-10 Japan Aviation Electronics Industry, Limited Electric connector having an excellent grounding function
US20080215029A1 (en) * 1993-01-22 2008-09-04 I-Flow Corporation Platen pump
USD578209S1 (en) * 2007-04-30 2008-10-07 Erbe Elektromedizin Gmbh Pump unit
WO2018096149A1 (de) * 2016-11-28 2018-05-31 Idorsia Pharmaceuticals Ltd Vorrichtung zur abgabe einer substanz
USD847209S1 (en) * 2018-01-26 2019-04-30 Osaa Innovation Aps Bag pump
CN110585517A (zh) * 2019-09-29 2019-12-20 莲花医疗用品有限公司 一种非重力输液器
CN111032119A (zh) * 2017-06-20 2020-04-17 瓦莱里塔斯有限公司 液压药剂输送装置的延时机构
GR1010059B (el) * 2020-08-10 2021-08-13 Φαρματεν Α.Β.Ε.Ε. Διαδικασια και συσκευη για την παρασκευη παχυρευστων φαρμακοτεχνικων μορφων
US11185629B2 (en) 2016-06-08 2021-11-30 Shl Medical Ag Dosing apparatus and injection device
US12128221B2 (en) 2020-05-29 2024-10-29 Windgap Medical, Inc. Dynamic mixing and delivery system for mixing a therapeutic agent in an injector or autoinjector

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2721752C2 (de) * 1977-05-13 1983-12-29 Siemens AG, 1000 Berlin und 8000 München In einen menschlichen oder tierischen Körper implantierbares Gerät zur Infusion einer medizinischen Flüssigkeit
SE427245B (sv) * 1982-01-29 1983-03-21 Sjoenell Goeran Forfarande for blandning av ett emne, t ex cytostatika, forvarat i en med gummiforslutning eller motsvarande forsedd ampull, med ett annat emne, t ex sterilt vatten, likasa forvarat i en med gummiforslutning eller motsv
US5078679A (en) * 1990-11-13 1992-01-07 Reese H William Post-surgical anesthesia at a continuous and progressively decreasing administration rate
GB9611562D0 (en) 1996-06-03 1996-08-07 Applied Research Systems Device
WO2007147741A1 (en) 2006-06-21 2007-12-27 Novo Nordisk A/S A one-hand operated drug mixing and expelling device
DE102007060131A1 (de) * 2007-12-13 2009-06-25 Technische Universität Dresden Verfahren und Vorrichtung zum luftfreien Befüllen von Gefäßanschlüssen im Medizinbereich

Citations (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE419869C (de) * 1924-10-23 1925-10-12 Robert Roehr Dr Schweinerotlauf-Impfbesteck
US2129983A (en) * 1936-04-06 1938-09-13 Bacon Jay Harvey Surgical appliance
US2362025A (en) * 1943-01-26 1944-11-07 Price Alison Howe Apparatus for administering blood plasma
US2496559A (en) * 1945-09-17 1950-02-07 Piechaczek Alojzy Surgical and medical syringes
US2693801A (en) * 1951-01-08 1954-11-09 Forcman Joseph Safety cutoff valve for liquid administering apparatus
US2699167A (en) * 1952-04-25 1955-01-11 Paul A Raiche Hypodermic injector
US2798488A (en) * 1954-09-15 1957-07-09 Merck & Co Inc Syringe unit
US2869543A (en) * 1957-08-23 1959-01-20 Iowa Cooperative Ass Injector
US3048171A (en) * 1958-11-03 1962-08-07 Bio Physical Res Inc Intravenous injection device
US3153414A (en) * 1962-02-02 1964-10-20 Abbott Lab Apparatus for the induced infusion of liquid from a flexible liquid container

Patent Citations (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE419869C (de) * 1924-10-23 1925-10-12 Robert Roehr Dr Schweinerotlauf-Impfbesteck
US2129983A (en) * 1936-04-06 1938-09-13 Bacon Jay Harvey Surgical appliance
US2362025A (en) * 1943-01-26 1944-11-07 Price Alison Howe Apparatus for administering blood plasma
US2496559A (en) * 1945-09-17 1950-02-07 Piechaczek Alojzy Surgical and medical syringes
US2693801A (en) * 1951-01-08 1954-11-09 Forcman Joseph Safety cutoff valve for liquid administering apparatus
US2699167A (en) * 1952-04-25 1955-01-11 Paul A Raiche Hypodermic injector
US2798488A (en) * 1954-09-15 1957-07-09 Merck & Co Inc Syringe unit
US2869543A (en) * 1957-08-23 1959-01-20 Iowa Cooperative Ass Injector
US3048171A (en) * 1958-11-03 1962-08-07 Bio Physical Res Inc Intravenous injection device
US3153414A (en) * 1962-02-02 1964-10-20 Abbott Lab Apparatus for the induced infusion of liquid from a flexible liquid container

Cited By (49)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3595232A (en) * 1968-08-19 1971-07-27 Saul Leibinsohn Nongravitational infusion assembly
US3895631A (en) * 1974-02-04 1975-07-22 Alza Corp Liquid infusion unit
US3888239A (en) * 1974-06-21 1975-06-10 Morton K Rubinstein Fluid injection system
US4065230A (en) * 1975-01-17 1977-12-27 Hart Associates, Inc. Reciprocating infusion pump and directional adapter set for use therewith
US4267836A (en) * 1976-11-12 1981-05-19 Whitney Douglass G Injection device and method
EP0014006A3 (en) * 1979-01-25 1980-09-17 Survival Technology, Inc. Automatic, plural spring actuated, injecting device
US4391600A (en) * 1979-03-09 1983-07-05 Avi, Inc. Nonpulsating IV pump and disposable pump chamber
US4410322A (en) * 1979-03-09 1983-10-18 Avi, Inc. Nonpulsating TV pump and disposable pump chamber
US4382753A (en) * 1979-03-09 1983-05-10 Avi, Inc. Nonpulsating IV pump and disposable pump chamber
US4381006A (en) * 1980-11-10 1983-04-26 Abbott Laboratories Continuous low flow rate fluid dispenser
US4666430A (en) * 1984-12-05 1987-05-19 I-Flow Corporation Infusion pump
WO1986006967A1 (en) * 1985-05-20 1986-12-04 Survival Technology, Inc. Automatic medicament ingredient mixing and injecting apparatus
US4689042A (en) * 1985-05-20 1987-08-25 Survival Technology, Inc. Automatic medicament ingredient mixing and injecting apparatus
US5318539A (en) * 1986-10-17 1994-06-07 Alexander G. B. O'Neil Liquid feeding apparatus utilizing capillary tubing, and syringe driver
US4857048A (en) * 1987-05-29 1989-08-15 Hewlett-Packard Company IV pump and disposable flow chamber with flow control
US5803712A (en) * 1988-05-17 1998-09-08 Patient Solutions, Inc. Method of measuring an occlusion in an infusion device with disposable elements
US6146109A (en) * 1988-05-17 2000-11-14 Alaris Medical Systems, Inc. Infusion device with disposable elements
US5320503A (en) * 1988-05-17 1994-06-14 Patient Solutions Inc. Infusion device with disposable elements
US5584667A (en) * 1988-05-17 1996-12-17 Davis; David L. Method of providing uniform flow from an infusion device
US6312227B1 (en) 1988-05-17 2001-11-06 I-Flow Corp. Infusion device with disposable elements
US5100389A (en) * 1988-06-21 1992-03-31 Vaillancourt Vincent L Ambulatory infusion pump
US4997420A (en) * 1989-12-28 1991-03-05 Lefevre Robert J Portable drug delivery device including pump with tapered barrel
US7337922B2 (en) 1992-01-24 2008-03-04 I-Flow Corporation Platen pump
US6251098B1 (en) 1992-01-24 2001-06-26 I-Flow, Corp. Fluid container for use with platen pump
US5911716A (en) * 1992-01-24 1999-06-15 I-Flow Corporation Platen pump
US6358239B1 (en) 1992-01-24 2002-03-19 I-Flow Corporation Platen pump
US20040108333A1 (en) * 1992-01-24 2004-06-10 Rake Kenneth W. Platen pump
US6871759B2 (en) 1992-01-24 2005-03-29 I-Flow Corporation Platen pump
US20050211725A1 (en) * 1992-01-24 2005-09-29 Rake Kenneth W Platen pump
US7083068B2 (en) 1992-01-24 2006-08-01 I-Flow Corporation Platen pump
US20080215029A1 (en) * 1993-01-22 2008-09-04 I-Flow Corporation Platen pump
EP1475114A3 (en) * 1994-09-02 2004-11-24 Societe De Conseils De Recherches Et D'applications Scientifiques S.A.S. Injection system suitable for the administration of semisolid, sustained-release pharmaceutical compositions of gelable peptide salts
EP0836505A4 (en) * 1995-06-06 2000-01-12 Science Inc MEDICINE DISPENSER
US6241125B1 (en) * 1996-10-24 2001-06-05 Kenneth H. Jacobsen System and kit accessories for dispensing reactive two component materials
US6234795B1 (en) * 2000-01-21 2001-05-22 Ultradent Products, Inc. Flexible mixer extender
US20070105433A1 (en) * 2005-11-07 2007-05-10 Japan Aviation Electronics Industry, Limited Electric connector having an excellent grounding function
US7458829B2 (en) 2005-11-07 2008-12-02 Japan Aviation Electronics Industry, Limited Electric connector having an excellent grounding function
USD578209S1 (en) * 2007-04-30 2008-10-07 Erbe Elektromedizin Gmbh Pump unit
US11185629B2 (en) 2016-06-08 2021-11-30 Shl Medical Ag Dosing apparatus and injection device
JP2019535441A (ja) * 2016-11-28 2019-12-12 イドルシア ファーマスーティカルズ リミテッドＩｄｏｒｓｉａ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ Ｌｔｄ 物質を投与する装置
WO2018096149A1 (de) * 2016-11-28 2018-05-31 Idorsia Pharmaceuticals Ltd Vorrichtung zur abgabe einer substanz
US11253652B2 (en) 2016-11-28 2022-02-22 Shl Medical Ag Device for dispensing a substance
JP7053614B2 (ja) 2016-11-28 2022-04-12 エスエイチエル・メディカル・アーゲー 物質を投与する装置
CN111032119A (zh) * 2017-06-20 2020-04-17 瓦莱里塔斯有限公司 液压药剂输送装置的延时机构
USD847209S1 (en) * 2018-01-26 2019-04-30 Osaa Innovation Aps Bag pump
CN110585517A (zh) * 2019-09-29 2019-12-20 莲花医疗用品有限公司 一种非重力输液器
CN110585517B (zh) * 2019-09-29 2024-07-02 莲花医疗用品有限公司 一种非重力输液器
US12128221B2 (en) 2020-05-29 2024-10-29 Windgap Medical, Inc. Dynamic mixing and delivery system for mixing a therapeutic agent in an injector or autoinjector
GR1010059B (el) * 2020-08-10 2021-08-13 Φαρματεν Α.Β.Ε.Ε. Διαδικασια και συσκευη για την παρασκευη παχυρευστων φαρμακοτεχνικων μορφων

Also Published As

Publication number Publication date
IL27371A (en) 1971-07-28
FR1510549A (fr) 1968-01-19
SE337449B (en)van) 1971-08-09
NL6701783A (en)van) 1967-08-08
DE1566649A1 (de) 1970-04-30
GB1114238A (en) 1968-05-22
BE693765A (en)van) 1967-07-17
CH473591A (de) 1969-06-15

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