US3131692A - Hypodermic injector - Google Patents

Hypodermic injector Download PDF

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Publication number
US3131692A
US3131692A US95718A US9571861A US3131692A US 3131692 A US3131692 A US 3131692A US 95718 A US95718 A US 95718A US 9571861 A US9571861 A US 9571861A US 3131692 A US3131692 A US 3131692A
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US
United States
Prior art keywords
guide members
ampoule
plunger
barrel
shell
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
US95718A
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English (en)
Inventor
Love Donglas Stanley
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Express Injector Co Ltd
Original Assignee
Express Injector Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Express Injector Co Ltd filed Critical Express Injector Co Ltd
Application granted granted Critical
Publication of US3131692A publication Critical patent/US3131692A/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/30—Syringes for injection by jet action, without needle, e.g. for use with replaceable ampoules or carpules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
    • A61M5/2422—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic using emptying means to expel or eject media, e.g. pistons, deformation of the ampoule, or telescoping of the ampoule
    • A61M5/2425—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic using emptying means to expel or eject media, e.g. pistons, deformation of the ampoule, or telescoping of the ampoule by compression of deformable ampoule or carpule wall

Definitions

  • the invention relates to an improved hypodermic injector of the kind capable of discharging a jet of liquid through the skin of a patient without the use of a hypodermic needle.
  • Such injectors are adapted to be fitted with an ampoule or container for liquid medicament and it has been proposed heretofore to expel the medicament from a discharge orifice in one end of the ampoule by a piston or follower which is forced down the ampoule by a spring operated plunger.
  • a hypodermic injector comprises a housing for supporting an ampoule in the form of an elongated shell having at its closed end a part of reduced cross section, two plungers arranged one within the other slidably mounted in said housing to engage the closed end of one of said ampoules when supported therein, the outer plunger being arranged to embrace that part of said ampoule of reduced cross section so as to give lateral support thereto, and means for driving first, said inner plunger into said reduced part of the ampoule and then both 'plungers together into the remainder of the ampoule, to cause medicament therein to be discharged in two pressure stages.
  • the means for driving said plungers comprise a spring operated mechanism mounted in a barrel concentric with said plungers and fixed to said housing.
  • FIG. 1 is an elevational view on an enlarged scale of an ampoule for use with the injector
  • FiG. 2 is an exploded section of FIG. 1,
  • FIG. 3 is a section showing the ampoule after the first stage of introversion
  • FIG. 5 is a sectional View of an injector with the ampoule illustrated in FIG. 1 therein, the injector being shown in a loaded condition
  • FIG. 6 is a sectional view on the line VlVl of FIG. 5 showing a safety latch in the locked position
  • FIG. 7 is a similar view to FIG. 6 but showing the safety latch in the unlocked position
  • FIG. 9 is a sectional view of the injector illustrated in FIG. 5, with the ampoule removed and the injector shown in the process of being loaded.
  • the injector comprises a tubular housing 9 having a socket in one end for receiving a cylindrical ampoule.
  • the ampoule which is shown on an enlarged scale in FIGS. 1 to 4, comprises an elongated shell 10 of thin ductile material the closed end of the shell being stepped at 12 to provide a part 13 of reduced diameter.
  • the ampoule shell is adapted to be closed by a plug 14 having a minute discharge orifice 15, the plug being retained in the shell by a ring 16.
  • the ampoule is a close fit in the housing 9 and is retained therein by a ferrule 19 which engages a flange 14a on the plug 14 and screws onto the housing.
  • an outer tubular plunger 18 in which is slidably mounted an inner plunger 17
  • the plunger 18 is provided at its lower end with a recess which fits closely over the reduced part 13 of the ampoule and provides lateral support for said part when this is acted upon by the inner plunger 1'7.
  • the inner plunger 17 is loaded upwardly in relation to the plunger 18 by means of a spring 21 which engages a head 17a on the upper end of the plunger 17 and a washer 22 secured on the outer plunger 13 by a circlip.
  • the outer plunger 18 is loaded upwardly by a spring 20 which engages between the housing 9 and the washer 22.
  • the said guide members 25 and 26 are retained locked together against the loading of the springs 27 and 28 by means of a ball and cone locking mechanism.
  • This mechanism comprises a spindle 29 slidable in the guide member 25 and normally loaded upwardly therein into the position shown in FIG. 5 by means of a spring 31.
  • the lower end of the guide member 25 is provided with a radial slot 32 in which is located a ball 33.
  • the guide member 26 is formed with a small circumferential recess 26a in which the ball 33 seats when the injector is in the condition shown in FIG. 5, the ball being retained in said recess by means of a cone shaped extension 29a on the lower end of the spindle 29.
  • the movement of the inner plunger is conveyed to the outer plunger by the pick-up shoulder 17 b thereon abutting the upper edge of the outer plunger 13.
  • the movement of the two plungers 17 and 18 together causes the ampoule to be introverted in the manner shown in FIG. 4 and the contents thereof to be discharged first under high pressure as the reduced part 13 is introverted and then under less high pressure as the walls adjacent thereto are introverted within the remainder of the shell.
  • the discharge in two pressure stages enables first the skin to be penetrated and secondly the medicament to be injected into subcutaneous tissues at a sufiiciently reduced pressure to prevent said tissues being damaged.
  • the use of two springs to propel the plungers has the advantage that the resonance of one spring is counterbalanced by the resonant frequency of the other, thus inequalities of pressure which cause pain during an injection are substantially prevented.
  • the spindle 29 is provided with a safety device in the form of a small sliding latch 36, see FIGS. 6 and 7.
  • This latch 36 is a slidable fit in a recess in the upper end of the guide member 25 and is retained therein by a dish shaped washer 37 and spring 3 1.
  • the spindle 29 passes through a hole 36b in the centre of the latch and is provided in the region of said hole with a reduced neck 2%, the air-angement being such that when the latch is in the position shown in FIG. 7 the spindle 29 is free to move, but when the latch is in the position shown in FIG. -8 the spindle 29 is locked.
  • the latch 36 is moved by the rotation of a control ring 38 and in the position shown in FIG. is loaded by a spring 39 so that the nose 36a thereon engages in notch 38a in said control ring.
  • a spring 39 On rotating the control ring 38 to the release position the latch 36 is displaced and is disengaged from spindle 29.
  • a spring 41 having a detent on one end, which can be engaged in one or other of the notches 38a or 38b in the control ring.
  • a loading device having a hollow plunger 40 shown in FIG. 9.
  • This device simply comprises a supporting socket not shown, for receiving the housing 9 and for providing :a seat for the shoulder 9a thereon, and a lever mechanism for operating the hollow plunger 40, which is arranged to engage with the step 42 on the cap 43 at the top of the injector.
  • the inwardly directed flange at the upper end of the housing 24 is provided with a number of radial recesses 24a see FIGS. 6 and 7.
  • the lower edge of the ring 38 is provided with a number of outwardly directed projections 38c which are capable of passing through said recesses 24a when the ring is rotated into the locking position of the safety latch as shown in FIG. 6.
  • a hypodermic injector according to claim 1 wherein means are provided operative after compression of said spring, to reposition both guide members in said housing.
US95718A 1960-03-23 1961-03-14 Hypodermic injector Expired - Lifetime US3131692A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB1035360 1960-03-23

Publications (1)

Publication Number Publication Date
US3131692A true US3131692A (en) 1964-05-05

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Family Applications (1)

Application Number Title Priority Date Filing Date
US95718A Expired - Lifetime US3131692A (en) 1960-03-23 1961-03-14 Hypodermic injector

Country Status (4)

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US (1) US3131692A (fr)
CH (1) CH394499A (fr)
DE (1) DE1195907B (fr)
GB (1) GB964585A (fr)

Cited By (48)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3335722A (en) * 1963-11-01 1967-08-15 Olin Mathieson Hypodermic device
US3688765A (en) * 1969-10-03 1972-09-05 Jack S Gasaway Hypodermic injection device
US4090512A (en) * 1976-09-02 1978-05-23 Doherty Norman R Device for spring-loading a needleless innoculator
US4165800A (en) * 1976-09-02 1979-08-28 Doherty Norman R Device for spring-loading a needleless innoculator
US4913699A (en) * 1988-03-14 1990-04-03 Parsons James S Disposable needleless injection system
US5024656A (en) * 1988-08-30 1991-06-18 Injet Medical Products, Inc. Gas-pressure-regulated needleless injection system
US5026343A (en) * 1988-11-21 1991-06-25 Walter Holzer Device for needleless hypodermic injection of medications
US5599302A (en) * 1995-01-09 1997-02-04 Medi-Ject Corporation Medical injection system and method, gas spring thereof and launching device using gas spring
US5643211A (en) * 1996-02-29 1997-07-01 Medi-Ject Corporation Nozzle assembly having a frangible plunger
US5697917A (en) * 1996-02-29 1997-12-16 Medi-Ject Corporation Nozzle assembly with adjustable plunger travel gap
US5722953A (en) * 1996-02-29 1998-03-03 Medi-Ject Corporation Nozzle assembly for injection device
US5769138A (en) * 1996-04-01 1998-06-23 Medi-Ject Corporation Nozzle and adapter for loading medicament into an injector
US5800388A (en) * 1996-02-29 1998-09-01 Medi-Ject Corporation Plunger/ram assembly adapted for a fluid injector
US5865795A (en) * 1996-02-29 1999-02-02 Medi-Ject Corporation Safety mechanism for injection devices
US5875976A (en) * 1996-12-24 1999-03-02 Medi-Ject Corporation Locking mechanism for nozzle assembly
US5921967A (en) * 1996-02-29 1999-07-13 Medi-Ject Corporation Plunger for nozzle assembly
US6210359B1 (en) 2000-01-21 2001-04-03 Jet Medica, L.L.C. Needleless syringe
WO2002083211A1 (fr) * 2001-04-13 2002-10-24 Penjet Corporation Injecteur modulaire sans aiguille a pression de gaz
US20030088214A1 (en) * 1999-10-11 2003-05-08 Felton International, Inc. Universal protector cap with auto-disable features for needle-free injectors
US6613011B2 (en) 2001-04-13 2003-09-02 Penjet Corporation Gas-pressured engine with valve
US6755220B2 (en) 2001-04-27 2004-06-29 Penjet Corporation Method and apparatus for filling or refilling a needle-less injector
US20040158195A1 (en) * 2003-02-06 2004-08-12 Sibert Gary J. Needle-free mass injection device
US6824526B2 (en) 2001-10-22 2004-11-30 Penjet Corporation Engine and diffuser for use with a needle-less injector
US20050192530A1 (en) * 2001-04-13 2005-09-01 Penjet Corporation Method and apparatus for needle-less injection with a degassed fluid
US7018356B2 (en) 2002-10-31 2006-03-28 Wise Roger R Method and apparatus for adjusting the contents of a needle-less injector
US20070027428A1 (en) * 2005-05-03 2007-02-01 Pharmajet, Inc. Vial system and method for needle-less injector
US20070118094A1 (en) * 2005-05-03 2007-05-24 John Bingham Needle-less injector and method of fluid delivery
US20080281261A1 (en) * 2005-05-03 2008-11-13 Genesis Medical Technologies, Inc. Needle-less injector
WO2009137486A1 (fr) * 2008-05-05 2009-11-12 Becton, Dickinson And Company Dispositif d'administration de médicaments doté d'une cartouche à extrémité distale agrandie
US20110245761A1 (en) * 2005-04-06 2011-10-06 Douglas Ivan Jennings Injection device
US9028451B2 (en) 2006-06-01 2015-05-12 Cilag Gmbh International Injection device
US9028453B2 (en) 2008-06-19 2015-05-12 Cilag Gmbh International Reusable auto-injector
US9072833B2 (en) 2006-06-01 2015-07-07 Cilag Gmbh International Injection device
US9358346B2 (en) 2005-08-30 2016-06-07 Cilag Gmbh International Needle assembly for a prefilled syringe system
US9408972B2 (en) 2011-08-02 2016-08-09 Pharmajet, Inc. Needle-free injection device
US9433735B2 (en) 2011-12-13 2016-09-06 Pharmajet Inc. Needle-free intradermal injection device
US9649441B2 (en) 2005-04-06 2017-05-16 Cilag Gmbh International Injection device (bayonet cap removal)
US9675757B2 (en) 2004-05-28 2017-06-13 Cilag Gmbh International Injection device
US9675758B2 (en) 2004-05-28 2017-06-13 Cilag Gmbh International Injection device
US9682194B2 (en) 2008-06-19 2017-06-20 Cilag Gmbh International Re-useable auto-injector with filling means
US9731080B2 (en) 2005-04-06 2017-08-15 Cilag Gmbh International Injection device
US9757520B2 (en) 2006-06-01 2017-09-12 Cilag Gmbh International Injection device
US9770558B2 (en) 2005-09-27 2017-09-26 Cilag Gmbh International Auto-injection device with needle protecting cap having outer and inner sleeves
US9895493B2 (en) 2004-05-28 2018-02-20 Cilag Gmbh International Injection device
US10709849B2 (en) 2013-06-11 2020-07-14 Cilag Gmbh International Guide for an injection device
US10799646B2 (en) 2013-06-11 2020-10-13 Cilag Gmbh International Injection device
US11123492B2 (en) 2013-06-11 2021-09-21 Cilag Gmbh International Injection device
US11173255B2 (en) 2013-06-11 2021-11-16 Cilag Gmbh International Injection device

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3403679A (en) * 1964-12-11 1968-10-01 Secr Defence Brit Hypodermic injection apparatus with a secondary capsule-collapsing means
US3518990A (en) * 1968-05-02 1970-07-07 Oscar H Banker Gun type inoculator
DE3839287A1 (de) * 1988-11-21 1990-05-23 Holzer Walter Verfahren und hilfsmittel zur nadellosen injektion
GB2581514A (en) * 2019-02-22 2020-08-26 Danby Medical Ltd Infusion Pump

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US2671347A (en) * 1950-06-24 1954-03-09 Scherer Corp R P Latch structure
US2704543A (en) * 1955-03-22 Hypo jet injector
GB735538A (en) * 1950-08-15 1955-08-24 Gerald Ohl Transue Improvements in or relating to hypodermic injection apparatus
US2762370A (en) * 1954-09-07 1956-09-11 Scherer Corp R P Hypodermic injector
GB772968A (en) * 1954-09-07 1957-04-17 Scherer Corp R P Improvements in or relating to hypodermic injector
US2832339A (en) * 1953-09-02 1958-04-29 Potter Pharmaceutical Corp Hypodermic injector
US2940446A (en) * 1958-02-26 1960-06-14 Becton Dickinson Co Hypodermic assembly

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1805731U (de) * 1959-12-16 1960-02-11 Friedrich Dr Med Burmester Spritzampulle.

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2704543A (en) * 1955-03-22 Hypo jet injector
US2671347A (en) * 1950-06-24 1954-03-09 Scherer Corp R P Latch structure
GB735538A (en) * 1950-08-15 1955-08-24 Gerald Ohl Transue Improvements in or relating to hypodermic injection apparatus
US2832339A (en) * 1953-09-02 1958-04-29 Potter Pharmaceutical Corp Hypodermic injector
US2762370A (en) * 1954-09-07 1956-09-11 Scherer Corp R P Hypodermic injector
GB772968A (en) * 1954-09-07 1957-04-17 Scherer Corp R P Improvements in or relating to hypodermic injector
US2940446A (en) * 1958-02-26 1960-06-14 Becton Dickinson Co Hypodermic assembly

Cited By (73)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3335722A (en) * 1963-11-01 1967-08-15 Olin Mathieson Hypodermic device
US3688765A (en) * 1969-10-03 1972-09-05 Jack S Gasaway Hypodermic injection device
US4090512A (en) * 1976-09-02 1978-05-23 Doherty Norman R Device for spring-loading a needleless innoculator
US4165800A (en) * 1976-09-02 1979-08-28 Doherty Norman R Device for spring-loading a needleless innoculator
US4913699A (en) * 1988-03-14 1990-04-03 Parsons James S Disposable needleless injection system
US5024656A (en) * 1988-08-30 1991-06-18 Injet Medical Products, Inc. Gas-pressure-regulated needleless injection system
US5026343A (en) * 1988-11-21 1991-06-25 Walter Holzer Device for needleless hypodermic injection of medications
US5846233A (en) * 1995-01-09 1998-12-08 Medi-Ject Corporation Coupling device for medical injection system
US5599302A (en) * 1995-01-09 1997-02-04 Medi-Ject Corporation Medical injection system and method, gas spring thereof and launching device using gas spring
US5919159A (en) * 1995-01-09 1999-07-06 Medi-Ject Corporation Medical injection system and method, gas spring thereof and launching device using gas spring
US5891085A (en) * 1995-01-09 1999-04-06 Medi-Ject Corporation Nozzle assembly with lost motion connection for medical injector assembly
US5643211A (en) * 1996-02-29 1997-07-01 Medi-Ject Corporation Nozzle assembly having a frangible plunger
US5865795A (en) * 1996-02-29 1999-02-02 Medi-Ject Corporation Safety mechanism for injection devices
US5722953A (en) * 1996-02-29 1998-03-03 Medi-Ject Corporation Nozzle assembly for injection device
US5697917A (en) * 1996-02-29 1997-12-16 Medi-Ject Corporation Nozzle assembly with adjustable plunger travel gap
US5921967A (en) * 1996-02-29 1999-07-13 Medi-Ject Corporation Plunger for nozzle assembly
US5800388A (en) * 1996-02-29 1998-09-01 Medi-Ject Corporation Plunger/ram assembly adapted for a fluid injector
US5769138A (en) * 1996-04-01 1998-06-23 Medi-Ject Corporation Nozzle and adapter for loading medicament into an injector
US5875976A (en) * 1996-12-24 1999-03-02 Medi-Ject Corporation Locking mechanism for nozzle assembly
US20060106333A1 (en) * 1999-10-11 2006-05-18 Leon Nanthaniel J Universal protector cap with auto-disable features for needle-free injectors
US20060287631A1 (en) * 1999-10-11 2006-12-21 Leon Nathaniel J Universal protector cap with auto-disable features for needle-free injectors
US20030088214A1 (en) * 1999-10-11 2003-05-08 Felton International, Inc. Universal protector cap with auto-disable features for needle-free injectors
US7074210B2 (en) * 1999-10-11 2006-07-11 Felton International, Inc. Universal protector cap with auto-disable features for needle-free injectors
US6210359B1 (en) 2000-01-21 2001-04-03 Jet Medica, L.L.C. Needleless syringe
US6613011B2 (en) 2001-04-13 2003-09-02 Penjet Corporation Gas-pressured engine with valve
US20050192530A1 (en) * 2001-04-13 2005-09-01 Penjet Corporation Method and apparatus for needle-less injection with a degassed fluid
AU2001253458B2 (en) * 2001-04-13 2005-10-27 Penjet Corporation Modular gas-pressured needle-less injector
AU2001253458C1 (en) * 2001-04-13 2006-05-18 Penjet Corporation Modular gas-pressured needle-less injector
US6613010B2 (en) 2001-04-13 2003-09-02 Penjet Corporation Modular gas-pressured needle-less injector
WO2002083211A1 (fr) * 2001-04-13 2002-10-24 Penjet Corporation Injecteur modulaire sans aiguille a pression de gaz
US6755220B2 (en) 2001-04-27 2004-06-29 Penjet Corporation Method and apparatus for filling or refilling a needle-less injector
US6824526B2 (en) 2001-10-22 2004-11-30 Penjet Corporation Engine and diffuser for use with a needle-less injector
US7018356B2 (en) 2002-10-31 2006-03-28 Wise Roger R Method and apparatus for adjusting the contents of a needle-less injector
US20040158195A1 (en) * 2003-02-06 2004-08-12 Sibert Gary J. Needle-free mass injection device
WO2004069313A1 (fr) * 2003-02-06 2004-08-19 Pfizer Products Inc. Dispositif d'injection de masse sans aiguille
US9675758B2 (en) 2004-05-28 2017-06-13 Cilag Gmbh International Injection device
US9675757B2 (en) 2004-05-28 2017-06-13 Cilag Gmbh International Injection device
US9895493B2 (en) 2004-05-28 2018-02-20 Cilag Gmbh International Injection device
US8968236B2 (en) * 2005-04-06 2015-03-03 Cilag Gmbh International Injection device
US20110245761A1 (en) * 2005-04-06 2011-10-06 Douglas Ivan Jennings Injection device
US9731080B2 (en) 2005-04-06 2017-08-15 Cilag Gmbh International Injection device
US9649441B2 (en) 2005-04-06 2017-05-16 Cilag Gmbh International Injection device (bayonet cap removal)
US10099011B2 (en) 2005-05-03 2018-10-16 Pharmajet, Inc. Needle-less injector and method of fluid delivery
US20080281261A1 (en) * 2005-05-03 2008-11-13 Genesis Medical Technologies, Inc. Needle-less injector
US8529500B2 (en) 2005-05-03 2013-09-10 Pharmajet, Inc. Needle-less injector and method of fluid delivery
US20070118094A1 (en) * 2005-05-03 2007-05-24 John Bingham Needle-less injector and method of fluid delivery
US7699802B2 (en) 2005-05-03 2010-04-20 Pharmajet, Inc. Needle-less injector
US20070027428A1 (en) * 2005-05-03 2007-02-01 Pharmajet, Inc. Vial system and method for needle-less injector
US7618393B2 (en) * 2005-05-03 2009-11-17 Pharmajet, Inc. Needle-less injector and method of fluid delivery
US9333300B2 (en) 2005-05-03 2016-05-10 Pharmajet, Inc. Needle-less injector and method of fluid delivery
US9358346B2 (en) 2005-08-30 2016-06-07 Cilag Gmbh International Needle assembly for a prefilled syringe system
US9770558B2 (en) 2005-09-27 2017-09-26 Cilag Gmbh International Auto-injection device with needle protecting cap having outer and inner sleeves
US9072833B2 (en) 2006-06-01 2015-07-07 Cilag Gmbh International Injection device
US9757520B2 (en) 2006-06-01 2017-09-12 Cilag Gmbh International Injection device
US9028451B2 (en) 2006-06-01 2015-05-12 Cilag Gmbh International Injection device
US11878147B2 (en) 2006-11-13 2024-01-23 Pharmajet Inc. Needle-less injector and method of fluid delivery
US10124117B2 (en) 2008-05-05 2018-11-13 Becton, Dickinson And Company Drug delivery device having cartridge with enlarged distal end
US20110092917A1 (en) * 2008-05-05 2011-04-21 Becton, Dickinson And Company Drug delivery device having cartridge with enlarged distal end
JP2011519681A (ja) * 2008-05-05 2011-07-14 ベクトン・ディキンソン・アンド・カンパニー 遠位側端部の拡大されたカートリッジを有する薬剤送達器材
WO2009137486A1 (fr) * 2008-05-05 2009-11-12 Becton, Dickinson And Company Dispositif d'administration de médicaments doté d'une cartouche à extrémité distale agrandie
US9028453B2 (en) 2008-06-19 2015-05-12 Cilag Gmbh International Reusable auto-injector
US9682194B2 (en) 2008-06-19 2017-06-20 Cilag Gmbh International Re-useable auto-injector with filling means
US10463795B2 (en) 2011-08-02 2019-11-05 Pharmajet Inc. Needle-free injection methods
US9408972B2 (en) 2011-08-02 2016-08-09 Pharmajet, Inc. Needle-free injection device
US11471603B2 (en) 2011-08-02 2022-10-18 Pharmajet, Inc. Needle-free injector
US10322238B2 (en) 2011-12-13 2019-06-18 Pharmajet, Inc. Needle-free intradermal injection device
US9700675B2 (en) 2011-12-13 2017-07-11 Pharmajet Inc. Needle-free intradermal injection device
US11154659B2 (en) 2011-12-13 2021-10-26 Pharmajet Inc. Needle-free intradermal injection device
US9433735B2 (en) 2011-12-13 2016-09-06 Pharmajet Inc. Needle-free intradermal injection device
US10709849B2 (en) 2013-06-11 2020-07-14 Cilag Gmbh International Guide for an injection device
US10799646B2 (en) 2013-06-11 2020-10-13 Cilag Gmbh International Injection device
US11123492B2 (en) 2013-06-11 2021-09-21 Cilag Gmbh International Injection device
US11173255B2 (en) 2013-06-11 2021-11-16 Cilag Gmbh International Injection device

Also Published As

Publication number Publication date
GB964585A (fr)
CH394499A (de) 1965-06-30
DE1195907B (de) 1965-07-01

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