US3029752A - Tablet making machine - Google Patents

Tablet making machine Download PDF

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Publication number
US3029752A
US3029752A US82824659A US3029752A US 3029752 A US3029752 A US 3029752A US 82824659 A US82824659 A US 82824659A US 3029752 A US3029752 A US 3029752A
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Prior art keywords
tablet making
making machine
lower
air
sockets
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Raymond G Frank
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Stokes F J Corp
F J STOKES CORP
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Stokes F J Corp
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    • BPERFORMING OPERATIONS; TRANSPORTING
    • B30PRESSES
    • B30BPRESSES IN GENERAL
    • B30B11/00Presses specially adapted for forming shaped articles from material in particulate or plastic state, e.g. briquetting presses, tabletting presses
    • B30B11/02Presses specially adapted for forming shaped articles from material in particulate or plastic state, e.g. briquetting presses, tabletting presses using a ram exerting pressure on the material in a moulding space
    • B30B11/08Presses specially adapted for forming shaped articles from material in particulate or plastic state, e.g. briquetting presses, tabletting presses using a ram exerting pressure on the material in a moulding space co-operating with moulds carried by a turntable
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B30PRESSES
    • B30BPRESSES IN GENERAL
    • B30B15/00Details of, or accessories for, presses; Auxiliary measures in connection with pressing
    • B30B15/0005Details of, or accessories for, presses; Auxiliary measures in connection with pressing for briquetting presses
    • B30B15/0011Details of, or accessories for, presses; Auxiliary measures in connection with pressing for briquetting presses lubricating means
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S425/00Plastic article or earthenware shaping or treating: apparatus
    • Y10S425/115Lubricator

Description

April 17, 1962 R. G. FRANK 3, 2

TABLET MAKING MACHINE Filed July 20, 1959 2 Sheets-Sheet 1 INVEN TOR. RAYMOND G. FRANK ATTORNEY April 17, 1962 R. G. FRANK 3,029,752

TABLET MAKING MACHINE Filed July 2Q, 1959 2 Sheets-Sheet 2 Fig. 2 I8 88 2o AIR 5 1 68 INVENTOR. s4 so 52 RAYMOND e. FRANK 52 BY 5 6 50 v @LLKHSQQQQ 58 6 AIR ATTORNEY United States Patent Q 3,029,752 TABLET MAKING MAC Raymond G. Frank, Ambler, Pa, assignor to F. .l. Stokes Corporation, Philadelphia, Pa, a corporation Filed July 20, 195% S631. No. 823,246 12 Claims. (Cl. 107--17) The present invention is directed to a tablet making machine, and more particularly to a tablet making machine which can be operated at high speeds for sustained periods of time without mechanical malfunction.

The use of automatic tablet making machines has become widespread, and machines for producing tablets of closely regulatedsize and shape at very high speeds have been developed. However, the powders supplied to such automatic tablet making machines frequently are not devoid of fine particles. These fine particles have a tendency to pass through the small radial clearances of the dies and the lower punches. This has been found to be true even though the radial clearances are maintained within a tolerance of 0.0002 inch for small diameters and 0.001 inch for larger diameters.

The accumulation of these fine powders in the lubrication film dispersed between the lower punches and their respective sockets in which such lower punches reciprocate within the rotary head has been found to lead to complete malfunction of the tablet making machine. Thus, such fine powders accumulate within the lubricant until the lower punches bind in their sockets. Such binding of the lower punches can reach such proportions that severe damage ensues to the pull-down side of the punch head within a veryjshort time period.

As the bearing contact between the pull-down side of the punch head and its associated cam track is limited, even a short period of operation after binding has been encountered will result in both damage to the punches and to the cam tracks.

- Binding of the punches within their sockets is materialiv aggravated upon the increase of the tabletting speed. While resort has been'had to careful selection of the lubricant in an attempt to avoid binding in high-speed operations, this has proved to be in the main unsatisfactory. In particular, it has been found that a lubricant which is satisfactory for one material may not work adequately with another.

' The development of high speed feeding means which are capable of delivering powders containing a high proportion of fines has greatly aggravated the punch binding problem. In particular, when resort is had to pressure or force feeding of such materials the problem is acutely aggravated.

This. invention has as an object the provision of a novel tablet making machine.

This invention has as another object the provision of a tablet makingrnachine which may be used to form tablets from powders containing a high proportion of fines at high speeds.

This invention has as yet another object the provision ofa tablet making machine in which binding of the lower punches within their sockets is substantially minimized.

This invention has as a still further object the provision of a tablet making machine in which lubrication of the lower punches is efliciently achieved.

Other objects will appear hereinafter.

For the purpose of illustrating the invention there is shownin the drawings a form which is presently preferred; it being understood, however, that this invention is not limited to the precise arrangements and instrumentalities shown.

FIGURE 1 is a fragmentary vertical sectional view through the tablet making machine of the present invention. I

"ice

FIGURE 2 is an enlarged fragmentary sectional view revealing the air baffling means of the present invention in association with the socket of a lower punch of the tablet making machine of FlGURE 1 together with the oil reservoir.

FIGURE 3 is a fragmentary sectional View revealing the operation of the means for delivering lubricant and the means for delivering air to the lower punch sockets of I the tablet making machine of the present invention.

FIGURE 4 is a sectional view taken on line 4-4 of iGURE 3.

FIGURE 5 is a sectional view taken on line 5-5 of FIGURE 3.

Referring to the drawings, there is shown therein a rotary tablet making machine of the present invention with many of the commonly known elements which are non-essential to the operation of the present invention eing omitted.

The tablet making machine of the present invention is designated generally as 19. The tablet making machine it) comprises the stationary lower frame 12 on which the rotary head 14 is rotatably carried by the spindle 16.

The upper punches 18 are guided in their sockets within the rotary head 14 and are in alignment with the dies 20. The dies 20 are carried within the rotary head 14 flush with the surface of the die table 22.

The lower punches 24 are carried within the lower punch sockets 26 within the rotary head 14. The lower punches 24 are in vertical alignment with the dies 20 and the upper punches 18 as will be evident to one having skill in this art.

The rotation of the rotary head 14 is achieved by the engagement of the worm 28 with the worm gear Stl, the worm 23 being driven by the prime mover 32.

The lower punches 24 ride on the lower punch cam track 34, with the pul'-down side 36 of the punch head 38 of each lower punch 24 being engaged with the lower punch cam track 34 during the portion of the tablet making cycle in which such lower punch 24 is in descended disposition. Such descended disposition for a lower punch 24 is shown at the left side of FIGURE 1.

During the compression portion of the tablet making cycle, the underside of the punch head 38 of each lower punch 24 is engaged with the lower roll 40 as shown at the right side of FIGURE 1.

The portion of the rotary tablet making machine it} set forth above is of standard construction, and no claim of invention is made to the same independent of the portion of such machine set forth below. Accordingly, a wide variety of tablet making machine embodiments incorporating the elements set forth above may be utilized in the tablet making machine iii of the present invention, since no claim is made to any particular type of element of the type specified above. I

The tablet making machine 10 of the present invention comprises the air channel 42- disposed within the bottom portion of the rotary head 14. The air channel 42 is an annulus and is in communication with a plurality of upright ports 44, so that the combination of the air channel 42 and the upright ports 44 serves as a manifold. Each upright port 44 is provided with a lateral port 46 which is in communication with the lower punch socket 26 for a lower punch 24. As will be seen particularly in FIGURE 2, the discharge opening of the lateral port 46 is positioned in the wall of the lower punch socket 26 at a height such that it is just above the tip shoulder 48 of the lower punch 24 in its descended position.

The seal mounting ring 50 is fixedly secured to the stationary lower frame 12 beneath the air channel 42. The seal mounting ring 50 forms the support on which the annular seals 52 and 52 are clamped by the seal holding ring 54-.

.4. 3 v V The seals 52 and 52 may be formed of any suitable sealing material, with self-lubricating polymers, such as the tetrafluoroethylene polymers designated Teflon, or with synthetic rubber or the like being satisfactory.

The seal mounting ring 50 is provided with an oil 7 opening 56 which is in communication both with the nel 42 above the seals 52 and 52 (see FIGURE 4).

The seal mounting ring 50 is also provided with an air opening 64 which is in communication both with the air duct 66 which enters into the seal mounting ring 50 from its underside, and the air port 68 which extends upwardly within the seal holding ring 54 throughout its entire height. The air port 68 discharges into the air channel 42 above the seals 52 and 52 (see FIGURE The air duct 66 is provided with a'T 70, so that a bifurcation of the air duct 66 may be effected, one arm thereof going to the seal holding ring 54 as above-indicated, and the other arm 66a thereof extending to the upper portion of the oil reservoir 72.

The oil reservoir 72 may be fixedly secured at a convenient point to the stationary lower frame 12, and is preferably provided with a window 74 through which its contents may be visually observed.

A pressure regulator 76 with an attendant gauge 78 may be provided in air duct 66. In addition, it is also desirable to provide the air duct 66 with a shut-off valve 80. In cases where it is desirable to lubricate punch sockets 26, a mist type lubricator 100 may be placed in air duct 66 after pressure regulator 76. The mist type lubricator 100 may be any one of a plurality of commercially available lubricators such as the micro-fog lubricator sold by Norgren Co., Englewood, Colorado.

The securement of the seal holding ring 54 to the seal mounting ring 50 may be accomplished by a variety of means, as by the bolt 82 which extends from the seal holding ring 54 into a threaded socket within the seal mounting ring 50.

Referring now particularly to FIGURE '2, an annular exhaust seal 84 is provided in an undercut groove 86 beneath the die table 22 spaced from the wall of the lower punch sockets 26 and juxtaposed to the mouth of the lateral ports 46. The annular exhaust seal 84 is provided with seal members 88 and 88 which are clamped to its inside end portion by the clamping element 96. Such seal members 88 and 88 may be formed of the same material as the seals '52 and 52.

As seen in FIGURE 1, the annular exhaust seal 84 is provided with at least one vacuum opening 92 which establishes a communication between the vacuum channel 94, which is positioned intermediate the inner portion of the annular exhaust seal 84 and the lower punch socket 26, and the exhaust duct 96. The exhaust duct 96 is in communication with a vacuum pump 98 by which the vacuum channel 94 may be evacuated to a suitable extent. The exhaust duct 96 may be provided with a filter 99 which is diagrammatically shown in FIGURE 1.

The operation of the tablet making machine of the present invention is as follows:

When the tablet making machine 10 is not in use the shut-off valve 80 may be closed (as for example by an automatic latching means connected to the spindle 16, not shown). This prevents the flow of air through the air port 68 in the seal holding ring 54. The level of oil in the oil reservoir 72 is equalized with that over seals 52 and 52 by the bifurcated line 66a which maintains the air pressure within oil reservoir 72 equal to that of air channel 42.

Air, and if lubrication is desired, oil dispersed into the air stream by mist lubricator 100 enters into the air channel 42 and then flows upwardly through the upright ports 44 and thence through the lateral ports 46. Dry or lubricated air in the form of an atomized spray is discharged onto the tip portion of each 'lower punch 24 when such lower punch 24 is in its descended disposition, as shown at the left side of FIGURE 1. The discharge of the oil onto the tip portion serves to lubricate the lower punch 24 in respect to its lower punch socket 26. The discharge of air from the lateral port 46 onto the tip portion of the lower punch 24 when the lower punch is in its descended disposition serves to provide an air baflle against the descent of powder fines about the shank of the lower punch 24 which is received within the lower punch socket 26.

When the lower punch is in its raised disposition, thus effecting compression of the powder being tabletted within the die 29, as shown at the right side of FIGURE 1, such compression being effected by the engagement of the underside of the punch head 38 of the lower punch 24 with the lower roll 40, the shank of the lower punch 24 blocks the mouth of the lateral port 46. In this manner pulsing of the oil and air to the tip portion of each lower punch 24 is achieved.

Since the head 14 rotates and the seals 52 are stationary, the oil from reservoir 72 is conveyed to the seals 52 by way of the duct 58 to prevent the seals 52 from overheating. The level of the oil Within the channel 42 is identical with the level of the oil in reservoir 72 since the pressure of the air in duct 66 is acting on the surface of the oil in reservoir 72 and channel 42. The oil in reservoir 72 is maintained at a level so that the level of the oil in channel 42 is below the upper surface of the ring 54. Thus, the oil in channel 42 does not interfere with the flow of pressurized air or pressurized air having an aerosolized lubricant which is being conveyed to the socket 26 by the ports 44.

The provision of the vacuum channel 94 minimizes the creation of airborne dust. The suction within the vacuum channel 94 is not sufficiently great so as to interfere with the lubrication of the lower punches 24, but is sufiiciently great to remove the powder fines blown from the tip portion of the lower punches 24 by the air issuing from the lateral ports .46. Such powder fines may be removed by filter 99 within the exhaust duct 96. Any oil recovered from the aerosolized lubricant spray introduced into socket 26 and withdrawn from the socket 26 by the suction of the vacuum pump 98 is thrown away since the amount of oil so recovered is very minute. The air removed from socket 26 by the vacuum pump 98 is discharged into the atmosphere through the exhaust port of the vacuum pump 98.

The air blast from the lateral port 46 prevents the flow of powder fines into the radial clearance between the lower punches 24 and their lower punch sockets 26, and accordingly eliminates the binding heretofore encountered from this cause. Furthermore, the discharge of oil onto the lower punches 24 from the lateral ports 46 provides a most efficient type of lubrication for the lower punches 24.

The present invention may be embodied in other specific forms without departing from the spirit or essential attributes thereof and, accordingly, reference should be made to the appended claims, rather than to the foregoing specification as indicating the scope of the invention.

I claim:

' 1. In a tablet making machine including a rotary'head, upper and lower punches carried within respective sockets in vertical alignment with dies in said rotary head, and means for introducing a pressurized fluid into each of the sockets for the lower punches just below each die com-- prising a separate port in said rotary head adjacent each into its associated lower punch socket.

' U a 2. In a tablet making machine including a rotary head, upper and lower punches carried within respective sockets in vertical alignment with dies in said rotary head, and means for introducing both a pressurized gas and a lubricant into each of the sockets for the lower punches just below each die.

3. In a tablet making machine as set forth in claim 2 wherein said means includes a passage in said rotary head, and conduit means connected to said passage for injecting said lubricant into said passage in response to flow of pressurized gas therethrough.

4. In a tablet making machine including a rotary head, upper and lower shouldered punches carried within respective sockets in vertical alignment with dies in said rotary head, a separate port in said rotary head adjacent each of the sockets for the lower punches, with eachof said ports discharging into the upper portion of its asso head adjacent each of the sockets for the lower punches which discharges into its associated lower punch socket below each'die, and means for exhausting such fluid from the tablet making machine in communication with each of the sockets for the lower punches.

6; ,In a tablet making machine including a rotary head, upper and lower shouldered punches carried within respective socketsin vertical alignment with dies in said rotary head, a separate port in said rotary head adjacent each of the sockets for the lower punches, with each of said ports discharging into the upper portion of its asso ciated lower punch socket at a point which is blocked by the shank of the lower punch received within such socket at one stage of the tablet making cycle and which is above the tip shoulder of the lower punch at another stage of the tablet making cycle, and means for introducing both a pressurized gas and an aerosolized lubricant into each of said ports.

7. In a tablet making machine including a rotary head, upper and lower punches having a shank and a die entering portion carried within respective sockets in vertical alignment with dies in said rotary head, a separate port in said rotary head adjacent each of the sockets tor the lower punches, with each of said ports discharging into the upper portion of its associated lower punch socket at a point which is blocked by the shank of the lower punch received within such socket at one stage of the tablet making cycle and which is above the shank of the lower punch at another stage of the tabletmaking cycle, means for introducing both a pressurized gas and a lubricant spray in communication with each of said ports, and means for exhausting gas from the tablet making machine in communication with each of the sockets for the lower punches.

8. In a tablet making machine including a fixed frame, a rotary head disposed above said fixed frame, upper and lower punches carried within sockets in vertical alignment with dies in said rotary head, an annular channel means in the bottom portion of said rotary head, sealing means on the upper surface of said fixed frame providing a fluid-tight floor for said annular channel means, and a separate port in said rotary head adjacent each of the sockets for the lower punches, with each of said ports being in communication with its associated lower punch socket and with said annular channel means.

9. in a tablet making machine in accordance with claim 8 wherein said annular channel means and said sealing means are concentrically positioned relativeto said rotary head.

10. In a tablet making machine in accordance with clann 8 which includes means for introducing a fluid through said frame into said annular channel.

11. In a tablet making machine in accordance with claim 10 which includes separatemeans for introducing a pressurized gas and a liquid lubricant into said annular channel with the level of liquid lubricant being below the point at which the gas is introduced into said channel, with each of said separate means extending through the fixed frame. a

12. In a tablet making machine in accordance with claim 10 which includes means for exhausting the fluid introduced into the annular channel in communication with each of the sockets for the lower punches.

References Cited in the file of this patent UNITED STATES PATENTS 1,289,570 Stokes Dec. 31, 1918 1,839,731 Baum Jan. 5, 1932 2,043,086 Westin et al. June 2, 1936 2,242,182 McCann May 13, 1941 2,444,282 Creevy June 29, 1948 2,909,912 Loewe et al. Oct. 27, 1959

US3029752A 1959-07-20 1959-07-20 Tablet making machine Expired - Lifetime US3029752A (en)

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DE1960ST016313 DE1299529B (en) 1959-07-20 1960-04-04 Rotary tablet machine

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Cited By (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3158111A (en) * 1962-06-06 1964-11-24 Smith Kline French Lab Method and apparatus for forming tablets
US3254377A (en) * 1963-04-22 1966-06-07 Glenn R Morton Fluid cooled, lubricated and sealed piston means for casting devices
US3309750A (en) * 1964-11-09 1967-03-21 E J Lavino & Co Apparatus and method for manufacturing brick
US3384035A (en) * 1965-06-02 1968-05-21 Pennsalt Chemicals Corp Industrial process and apparatus
US3599578A (en) * 1968-11-18 1971-08-17 Fumio Sato Apparatus for producing press-molded articles
US3687588A (en) * 1970-09-08 1972-08-29 Wolverine Pentronix Lubricated die and punch assembly for compacting powder material
US3887685A (en) * 1972-08-03 1975-06-03 Von Roll Ag Automatic feed block molding press for granular materials
US4047866A (en) * 1976-11-22 1977-09-13 The Dow Chemical Company Automatic self-lubricating rotary tablet press
US4147489A (en) * 1977-06-22 1979-04-03 British Nuclear Fuels Ltd. Powder compacting presses
US4292017A (en) * 1980-07-09 1981-09-29 Doepel Wallace A Apparatus for compressing tablets
US4420028A (en) * 1980-10-29 1983-12-13 Outboard Marine Corporation Lubrication system for a die casting machine
US5407339A (en) * 1993-09-27 1995-04-18 Vector Corporation Triturate tablet machine
WO2002074528A1 (en) * 2001-03-16 2002-09-26 I.M.A Industria Macchine Automatiche S.P.A. A tablet press machine
WO2003028618A2 (en) * 2001-09-28 2003-04-10 Mcneil-Ppc, Inc. Systems, methods and apparatuses for manufacturing dosage forms
US20030232083A1 (en) * 2001-09-28 2003-12-18 David Wynn Modified release dosage form
US20050008696A1 (en) * 2001-09-28 2005-01-13 Sowden Harry S. Systems, methods and apparatuses for manufacturing dosage forms
US7838026B2 (en) 2001-09-28 2010-11-23 Mcneil-Ppc, Inc. Burst-release polymer composition and dosage forms comprising the same

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3714031A1 (en) * 1987-04-27 1988-11-10 Fette Wilhelm Gmbh A rotary tableting machine

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US1289570A (en) * 1914-11-30 1918-12-31 Francis J Stokes Rotary tablet-machine.
US1839731A (en) * 1930-02-05 1932-01-05 Nat Equip Co Confection making apparatus
US2043086A (en) * 1934-04-07 1936-06-02 Stokes Machine Co Tablet compressing machine
US2242182A (en) * 1938-07-23 1941-05-13 Elizabeth S Mccann Machine for flock printing
US2444282A (en) * 1944-05-11 1948-06-29 Glaxo Lab Ltd Manufacture of compressed tablets and the like from finely divided ingredients
US2909912A (en) * 1955-08-19 1959-10-27 Loewe Siegmund Magnetic tape recorder with friction drive

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DE485734C (en) * 1929-11-04 Friedrich Susanka Press for tablets, troches, Brikette o. The like.
DE648412C (en) * 1935-05-25 1937-07-30 Fritz Kilian Fa Method and apparatus for the production of Huelltabletten by Umpressung of core tablets with pelleting
DE967423C (en) * 1951-08-24 1957-11-21 Friedrich Horn Maschinenfabrik A rotary press and process for the preparation of compacts having a rotary press
DE873044C (en) * 1951-10-14 1953-04-09 Schaudt Maschb G M B H Rotary tablet press
DE1789482U (en) * 1959-04-07 1959-05-27 Mueller Ernst Kg Device for dedusting of tablets.

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1289570A (en) * 1914-11-30 1918-12-31 Francis J Stokes Rotary tablet-machine.
US1839731A (en) * 1930-02-05 1932-01-05 Nat Equip Co Confection making apparatus
US2043086A (en) * 1934-04-07 1936-06-02 Stokes Machine Co Tablet compressing machine
US2242182A (en) * 1938-07-23 1941-05-13 Elizabeth S Mccann Machine for flock printing
US2444282A (en) * 1944-05-11 1948-06-29 Glaxo Lab Ltd Manufacture of compressed tablets and the like from finely divided ingredients
US2909912A (en) * 1955-08-19 1959-10-27 Loewe Siegmund Magnetic tape recorder with friction drive

Cited By (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3158111A (en) * 1962-06-06 1964-11-24 Smith Kline French Lab Method and apparatus for forming tablets
US3254377A (en) * 1963-04-22 1966-06-07 Glenn R Morton Fluid cooled, lubricated and sealed piston means for casting devices
US3309750A (en) * 1964-11-09 1967-03-21 E J Lavino & Co Apparatus and method for manufacturing brick
US3384035A (en) * 1965-06-02 1968-05-21 Pennsalt Chemicals Corp Industrial process and apparatus
US3599578A (en) * 1968-11-18 1971-08-17 Fumio Sato Apparatus for producing press-molded articles
US3687588A (en) * 1970-09-08 1972-08-29 Wolverine Pentronix Lubricated die and punch assembly for compacting powder material
US3887685A (en) * 1972-08-03 1975-06-03 Von Roll Ag Automatic feed block molding press for granular materials
US4047866A (en) * 1976-11-22 1977-09-13 The Dow Chemical Company Automatic self-lubricating rotary tablet press
US4147489A (en) * 1977-06-22 1979-04-03 British Nuclear Fuels Ltd. Powder compacting presses
US4292017A (en) * 1980-07-09 1981-09-29 Doepel Wallace A Apparatus for compressing tablets
US4420028A (en) * 1980-10-29 1983-12-13 Outboard Marine Corporation Lubrication system for a die casting machine
US5407339A (en) * 1993-09-27 1995-04-18 Vector Corporation Triturate tablet machine
US20040067275A1 (en) * 2001-03-16 2004-04-08 Roberto Trebbi Tablet press machine
CN100491112C (en) 2001-03-16 2009-05-27 I.M.A.工业机械自动装置股份公司 Tablet press machine
WO2002074528A1 (en) * 2001-03-16 2002-09-26 I.M.A Industria Macchine Automatiche S.P.A. A tablet press machine
US6997691B2 (en) 2001-03-16 2006-02-14 I.M.A. Industria Macchine Automatiche S.P.A. Tablet press machine
WO2003028618A3 (en) * 2001-09-28 2003-08-14 Mcneil Ppc Inc Systems, methods and apparatuses for manufacturing dosage forms
US20040126425A1 (en) * 2001-09-28 2004-07-01 Sowden Harry S. Systems, methods and apparatuses for manufacturing dosage forms
US20040137057A1 (en) * 2001-09-28 2004-07-15 Sowden Harry S. Systems, methods and apparatuses for manufacturing dosage forms
US6767200B2 (en) 2001-09-28 2004-07-27 Mcneil-Ppc, Inc. Systems, methods and apparatuses for manufacturing dosage forms
US20050008696A1 (en) * 2001-09-28 2005-01-13 Sowden Harry S. Systems, methods and apparatuses for manufacturing dosage forms
US20030232083A1 (en) * 2001-09-28 2003-12-18 David Wynn Modified release dosage form
US7323129B2 (en) * 2001-09-28 2008-01-29 Omj Ireland Limited Systems, methods and apparatuses for manufacturing dosage forms
US7361006B2 (en) * 2001-09-28 2008-04-22 Mcneil-Ppc, Inc. Systems, methods and apparatuses for manufacturing dosage forms
WO2003028618A2 (en) * 2001-09-28 2003-04-10 Mcneil-Ppc, Inc. Systems, methods and apparatuses for manufacturing dosage forms
US7635490B2 (en) 2001-09-28 2009-12-22 Mcneil-Ppc, Inc. Modified release dosage form
US7838026B2 (en) 2001-09-28 2010-11-23 Mcneil-Ppc, Inc. Burst-release polymer composition and dosage forms comprising the same
US8114328B2 (en) 2001-09-28 2012-02-14 Mcneil-Ppc, Inc. Method of coating a dosage form comprising a first medicant
US8673190B2 (en) 2001-09-28 2014-03-18 Mcneil-Ppc, Inc. Method for manufacturing dosage forms

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