US20220146403A1 - Microparticle measurement device, microparticle sorting device, microparticle measurement system, and microparticle sorting system - Google Patents
Microparticle measurement device, microparticle sorting device, microparticle measurement system, and microparticle sorting system Download PDFInfo
- Publication number
- US20220146403A1 US20220146403A1 US17/433,740 US202017433740A US2022146403A1 US 20220146403 A1 US20220146403 A1 US 20220146403A1 US 202017433740 A US202017433740 A US 202017433740A US 2022146403 A1 US2022146403 A1 US 2022146403A1
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- United States
- Prior art keywords
- excitation light
- microparticles
- microparticle
- light irradiation
- objective lenses
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Classifications
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- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Electro-optical investigation, e.g. flow cytometers
- G01N15/1434—Electro-optical investigation, e.g. flow cytometers using an analyser being characterised by its optical arrangement
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- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
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- G01N15/02—Investigating particle size or size distribution
- G01N15/0205—Investigating particle size or size distribution by optical means, e.g. by light scattering, diffraction, holography or imaging
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Electro-optical investigation, e.g. flow cytometers
- G01N15/1456—Electro-optical investigation, e.g. flow cytometers without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals
- G01N15/1459—Electro-optical investigation, e.g. flow cytometers without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals the analysis being performed on a sample stream
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
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- G—PHYSICS
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- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
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- G—PHYSICS
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- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
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- G02B13/14—Optical objectives specially designed for the purposes specified below for use with infrared or ultraviolet radiation
- G02B13/143—Optical objectives specially designed for the purposes specified below for use with infrared or ultraviolet radiation for use with ultraviolet radiation
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- G—PHYSICS
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- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
- G01N2015/0065—Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials biological, e.g. blood
- G01N2015/0073—Red blood cells
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- G—PHYSICS
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- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
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- G01N15/02—Investigating particle size or size distribution
- G01N2015/0288—Sorting the particles
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
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- G01N15/02—Investigating particle size or size distribution
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- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
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- G01N2015/1006—Investigating individual particles for cytology
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- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
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- G01N15/14—Electro-optical investigation, e.g. flow cytometers
- G01N2015/149—Sorting the particles
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Electro-optical investigation, e.g. flow cytometers
- G01N2015/1493—Particle size
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Electro-optical investigation, e.g. flow cytometers
- G01N2015/1497—Particle shape
Landscapes
- Chemical & Material Sciences (AREA)
- Physics & Mathematics (AREA)
- General Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Dispersion Chemistry (AREA)
- Optics & Photonics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Toxicology (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2019040421A JP2020143991A (ja) | 2019-03-06 | 2019-03-06 | 微小粒子測定装置、微小粒子分取装置、微小粒子測定システム及び微小粒子分取システム |
JP2019-040421 | 2019-03-06 | ||
PCT/JP2020/001207 WO2020179237A1 (ja) | 2019-03-06 | 2020-01-16 | 微小粒子測定装置、微小粒子分取装置、微小粒子測定システム及び微小粒子分取システム |
Publications (1)
Publication Number | Publication Date |
---|---|
US20220146403A1 true US20220146403A1 (en) | 2022-05-12 |
Family
ID=72337515
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US17/433,740 Pending US20220146403A1 (en) | 2019-03-06 | 2020-01-16 | Microparticle measurement device, microparticle sorting device, microparticle measurement system, and microparticle sorting system |
Country Status (3)
Country | Link |
---|---|
US (1) | US20220146403A1 (ja) |
JP (1) | JP2020143991A (ja) |
WO (1) | WO2020179237A1 (ja) |
Citations (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8004661B2 (en) * | 2008-06-30 | 2011-08-23 | Microbix Biosystems Inc. | Method and apparatus for sorting cells |
US20120211679A1 (en) * | 2010-08-20 | 2012-08-23 | Bio-Rad Laboratories, Inc. | Cytometry system with solid numerical-aperture-increasing lens |
US20120238032A1 (en) * | 2011-03-18 | 2012-09-20 | International Business Machines Corporation | Lab on a chip |
US20130201322A1 (en) * | 2010-08-18 | 2013-08-08 | Nanoentek, Inc. | Fluorescent microscope for observing multiple fluorescent images, fluorescent image surveying method using the same, and multiple fluorescent image observing system |
US20130342838A1 (en) * | 2012-06-22 | 2013-12-26 | Azbil Corporation | Optical particle detecting device and particle detecting method |
US20140367315A1 (en) * | 2011-12-29 | 2014-12-18 | Danmarks Tekniske Universitet | System for sorting microscopic objects using electromagnetic radiation |
US20180188173A1 (en) * | 2015-12-22 | 2018-07-05 | University Of Maryland, College Park | Cell classification based on mechanical signature of nucleus |
US20190070608A1 (en) * | 2017-09-06 | 2019-03-07 | Hamamatsu Photonics K.K. | Cell observation system and cell observation method |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP3218108B2 (ja) * | 1993-02-10 | 2001-10-15 | シスメックス株式会社 | イメージングフローサイトメータ |
JP4262380B2 (ja) * | 1999-12-24 | 2009-05-13 | オリンパス株式会社 | 光量測定装置 |
JP4756948B2 (ja) * | 2005-08-08 | 2011-08-24 | ベイバイオサイエンス株式会社 | フローサイトメータおよびフローサイトメトリ方法 |
JP4251193B2 (ja) * | 2006-05-23 | 2009-04-08 | コニカミノルタセンシング株式会社 | 反射特性測定装置 |
JP2016012114A (ja) * | 2014-06-02 | 2016-01-21 | オリンパス株式会社 | 照明装置、これを有する顕微鏡装置及び顕微鏡観察方法 |
-
2019
- 2019-03-06 JP JP2019040421A patent/JP2020143991A/ja active Pending
-
2020
- 2020-01-16 WO PCT/JP2020/001207 patent/WO2020179237A1/ja active Application Filing
- 2020-01-16 US US17/433,740 patent/US20220146403A1/en active Pending
Patent Citations (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8004661B2 (en) * | 2008-06-30 | 2011-08-23 | Microbix Biosystems Inc. | Method and apparatus for sorting cells |
US20130201322A1 (en) * | 2010-08-18 | 2013-08-08 | Nanoentek, Inc. | Fluorescent microscope for observing multiple fluorescent images, fluorescent image surveying method using the same, and multiple fluorescent image observing system |
US20120211679A1 (en) * | 2010-08-20 | 2012-08-23 | Bio-Rad Laboratories, Inc. | Cytometry system with solid numerical-aperture-increasing lens |
US20120238032A1 (en) * | 2011-03-18 | 2012-09-20 | International Business Machines Corporation | Lab on a chip |
US20140367315A1 (en) * | 2011-12-29 | 2014-12-18 | Danmarks Tekniske Universitet | System for sorting microscopic objects using electromagnetic radiation |
US20130342838A1 (en) * | 2012-06-22 | 2013-12-26 | Azbil Corporation | Optical particle detecting device and particle detecting method |
US20180188173A1 (en) * | 2015-12-22 | 2018-07-05 | University Of Maryland, College Park | Cell classification based on mechanical signature of nucleus |
US20190070608A1 (en) * | 2017-09-06 | 2019-03-07 | Hamamatsu Photonics K.K. | Cell observation system and cell observation method |
Also Published As
Publication number | Publication date |
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JP2020143991A (ja) | 2020-09-10 |
WO2020179237A1 (ja) | 2020-09-10 |
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