US20220128470A1 - Microplate reader - Google Patents
Microplate reader Download PDFInfo
- Publication number
- US20220128470A1 US20220128470A1 US17/503,732 US202117503732A US2022128470A1 US 20220128470 A1 US20220128470 A1 US 20220128470A1 US 202117503732 A US202117503732 A US 202117503732A US 2022128470 A1 US2022128470 A1 US 2022128470A1
- Authority
- US
- United States
- Prior art keywords
- microplate
- interface device
- microplate reader
- wells
- receiving apparatus
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 230000003287 optical effect Effects 0.000 claims abstract description 40
- 238000005259 measurement Methods 0.000 claims abstract description 34
- 230000007246 mechanism Effects 0.000 claims abstract description 10
- 230000005855 radiation Effects 0.000 claims abstract description 7
- 239000007789 gas Substances 0.000 claims description 14
- 230000005284 excitation Effects 0.000 claims description 9
- 230000001133 acceleration Effects 0.000 claims description 7
- 238000004140 cleaning Methods 0.000 claims description 7
- 239000003153 chemical reaction reagent Substances 0.000 claims description 6
- 238000009826 distribution Methods 0.000 claims description 6
- 238000005286 illumination Methods 0.000 claims description 6
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 claims description 4
- 230000001105 regulatory effect Effects 0.000 claims description 4
- 238000007664 blowing Methods 0.000 claims description 3
- 230000008859 change Effects 0.000 claims description 3
- 238000001816 cooling Methods 0.000 claims description 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 3
- 229910001868 water Inorganic materials 0.000 claims description 3
- CURLTUGMZLYLDI-UHFFFAOYSA-N Carbon dioxide Chemical compound O=C=O CURLTUGMZLYLDI-UHFFFAOYSA-N 0.000 claims description 2
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 claims description 2
- 238000009529 body temperature measurement Methods 0.000 claims description 2
- 229910002092 carbon dioxide Inorganic materials 0.000 claims description 2
- 230000008878 coupling Effects 0.000 claims description 2
- 238000010168 coupling process Methods 0.000 claims description 2
- 238000005859 coupling reaction Methods 0.000 claims description 2
- 230000000249 desinfective effect Effects 0.000 claims description 2
- 230000005672 electromagnetic field Effects 0.000 claims description 2
- 229910052757 nitrogen Inorganic materials 0.000 claims description 2
- 239000001301 oxygen Substances 0.000 claims description 2
- 229910052760 oxygen Inorganic materials 0.000 claims description 2
- 230000008054 signal transmission Effects 0.000 claims description 2
- 238000004891 communication Methods 0.000 abstract description 2
- 239000000523 sample Substances 0.000 description 20
- 238000006243 chemical reaction Methods 0.000 description 9
- 238000003780 insertion Methods 0.000 description 5
- 230000037431 insertion Effects 0.000 description 5
- 238000001514 detection method Methods 0.000 description 4
- 238000010438 heat treatment Methods 0.000 description 4
- 238000000034 method Methods 0.000 description 4
- 238000003860 storage Methods 0.000 description 4
- 238000013461 design Methods 0.000 description 3
- 238000011534 incubation Methods 0.000 description 3
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- 238000012797 qualification Methods 0.000 description 3
- 238000010521 absorption reaction Methods 0.000 description 2
- 230000005540 biological transmission Effects 0.000 description 2
- 238000010276 construction Methods 0.000 description 2
- 238000010586 diagram Methods 0.000 description 2
- 239000007788 liquid Substances 0.000 description 2
- 238000004020 luminiscence type Methods 0.000 description 2
- 230000006978 adaptation Effects 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 238000012790 confirmation Methods 0.000 description 1
- 230000009977 dual effect Effects 0.000 description 1
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- 244000005700 microbiome Species 0.000 description 1
- 239000003595 mist Substances 0.000 description 1
- 238000002663 nebulization Methods 0.000 description 1
- 230000003534 oscillatory effect Effects 0.000 description 1
- 238000005375 photometry Methods 0.000 description 1
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- 230000009469 supplementation Effects 0.000 description 1
- 239000000725 suspension Substances 0.000 description 1
- 238000002604 ultrasonography Methods 0.000 description 1
Images
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/645—Specially adapted constructive features of fluorimeters
- G01N21/6452—Individual samples arranged in a regular 2D-array, e.g. multiwell plates
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/508—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
- B01L3/5085—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above for multiple samples, e.g. microtitration plates
- B01L3/50851—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above for multiple samples, e.g. microtitration plates specially adapted for heating or cooling samples
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L9/00—Supporting devices; Holding devices
- B01L9/52—Supports specially adapted for flat sample carriers, e.g. for plates, slides, chips
- B01L9/523—Supports specially adapted for flat sample carriers, e.g. for plates, slides, chips for multisample carriers, e.g. used for microtitration plates
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
- G01N21/251—Colorimeters; Construction thereof
- G01N21/253—Colorimeters; Construction thereof for batch operation, i.e. multisample apparatus
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/01—Arrangements or apparatus for facilitating the optical investigation
- G01N21/03—Cuvette constructions
- G01N2021/0367—Supports of cells, e.g. pivotable
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/01—Arrangements or apparatus for facilitating the optical investigation
- G01N21/03—Cuvette constructions
- G01N2021/0367—Supports of cells, e.g. pivotable
- G01N2021/0371—Supports combined with sample intake
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N2035/00346—Heating or cooling arrangements
- G01N2035/00356—Holding samples at elevated temperature (incubation)
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/02—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
- G01N35/04—Details of the conveyor system
- G01N2035/0401—Sample carriers, cuvettes or reaction vessels
- G01N2035/0418—Plate elements with several rows of samples
- G01N2035/0422—Plate elements with several rows of samples carried on a linear conveyor
- G01N2035/0424—Two or more linear conveyors
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/01—Arrangements or apparatus for facilitating the optical investigation
- G01N21/03—Cuvette constructions
- G01N21/0332—Cuvette constructions with temperature control
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- General Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Clinical Laboratory Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Hematology (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE102020128003.3 | 2020-10-23 | ||
DE102020128003.3A DE102020128003A1 (de) | 2020-10-23 | 2020-10-23 | Mikroplatten-Lesegerät |
Publications (1)
Publication Number | Publication Date |
---|---|
US20220128470A1 true US20220128470A1 (en) | 2022-04-28 |
Family
ID=73747495
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US17/503,732 Pending US20220128470A1 (en) | 2020-10-23 | 2021-10-18 | Microplate reader |
Country Status (3)
Country | Link |
---|---|
US (1) | US20220128470A1 (de) |
EP (1) | EP3988924B1 (de) |
DE (1) | DE102020128003A1 (de) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20210345019A1 (en) * | 2018-10-01 | 2021-11-04 | Elemental Machines, Inc. | Method and Apparatus for Local Sensing |
US20230085933A1 (en) * | 2021-09-21 | 2023-03-23 | The Government of the United States of America, as represented by the Secretary of Homeland Security | Media holder for sample preparation |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE102021112938A1 (de) | 2021-05-19 | 2022-11-24 | Bmg Labtech Gmbh | Mikroplatten-Lesegerät |
Family Cites Families (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5849486A (en) * | 1993-11-01 | 1998-12-15 | Nanogen, Inc. | Methods for hybridization analysis utilizing electrically controlled hybridization |
US6399023B1 (en) * | 1996-04-16 | 2002-06-04 | Caliper Technologies Corp. | Analytical system and method |
US6358387B1 (en) * | 2000-03-27 | 2002-03-19 | Caliper Technologies Corporation | Ultra high throughput microfluidic analytical systems and methods |
WO2002072423A1 (en) * | 2001-03-09 | 2002-09-19 | Biomicro Systems, Inc. | Microplate lid |
US7692783B2 (en) * | 2006-02-13 | 2010-04-06 | Pacific Biosciences Of California | Methods and systems for simultaneous real-time monitoring of optical signals from multiple sources |
US20080044879A1 (en) * | 2006-08-17 | 2008-02-21 | The Charles Stark Draper Laboratory, Inc. | Systems and methods of voltage-gated ion channel assays |
FI20075439A0 (fi) * | 2007-06-12 | 2007-06-12 | Wallac Oy | Automatisoitu instrumentointi ja menetelmä näytteiden mittaamiseksi |
DE102008025992B4 (de) * | 2008-05-30 | 2011-01-27 | Siemens Healthcare Diagnostics Gmbh | Titerplatte und Verfahren zur Detektion eines Analyten |
US20100184616A1 (en) * | 2009-01-20 | 2010-07-22 | Bio-Rad Laboratories, Inc. | Spatially controlled illumination of biological sample array through wedge-shaped support |
CH703700A2 (de) * | 2010-09-08 | 2012-03-15 | Tecan Trading Ag | Kontrolle der Gasatmosphäre in Mikroplatten-Readern. |
US8858886B1 (en) * | 2013-05-08 | 2014-10-14 | Agilent Technologies, Inc. | Scanning system with interchangeable optical cartridges for fluorescence measurements |
CH708820A1 (de) * | 2013-11-07 | 2015-05-15 | Tecan Trading Ag | Inkubationskassette. |
US11200698B2 (en) * | 2017-06-01 | 2021-12-14 | Germaine Laboratories, Inc. | Devices and systems for data-based analysis of objects |
-
2020
- 2020-10-23 DE DE102020128003.3A patent/DE102020128003A1/de active Pending
-
2021
- 2021-09-29 EP EP21199753.1A patent/EP3988924B1/de active Active
- 2021-10-18 US US17/503,732 patent/US20220128470A1/en active Pending
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20210345019A1 (en) * | 2018-10-01 | 2021-11-04 | Elemental Machines, Inc. | Method and Apparatus for Local Sensing |
US20230085933A1 (en) * | 2021-09-21 | 2023-03-23 | The Government of the United States of America, as represented by the Secretary of Homeland Security | Media holder for sample preparation |
US11958053B2 (en) * | 2021-09-21 | 2024-04-16 | The Government of the United States of America, as represented by the Secretary of Homeland Security | Media holder for sample preparation |
Also Published As
Publication number | Publication date |
---|---|
EP3988924B1 (de) | 2023-11-29 |
DE102020128003A1 (de) | 2020-12-31 |
EP3988924A3 (de) | 2022-07-20 |
EP3988924A2 (de) | 2022-04-27 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
AS | Assignment |
Owner name: BMG LABTECH GMBH, GERMANY Free format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNOR:RAGER, STEFAN;REEL/FRAME:057820/0938 Effective date: 20211012 |
|
STPP | Information on status: patent application and granting procedure in general |
Free format text: DOCKETED NEW CASE - READY FOR EXAMINATION |
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STPP | Information on status: patent application and granting procedure in general |
Free format text: NON FINAL ACTION MAILED |