US20220072012A1 - Ursodeoxycholic acid-containing agent for treating or preventing presbyopia - Google Patents
Ursodeoxycholic acid-containing agent for treating or preventing presbyopia Download PDFInfo
- Publication number
- US20220072012A1 US20220072012A1 US17/414,285 US201917414285A US2022072012A1 US 20220072012 A1 US20220072012 A1 US 20220072012A1 US 201917414285 A US201917414285 A US 201917414285A US 2022072012 A1 US2022072012 A1 US 2022072012A1
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- US
- United States
- Prior art keywords
- ursodeoxycholic acid
- ester
- acid
- lens
- eye
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
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Classifications
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/10—Ophthalmic agents for accommodation disorders, e.g. myopia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/38—Cellulose; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Ophthalmology & Optometry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (3)
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| JP2018236717 | 2018-12-18 | ||
| JP2018-236717 | 2018-12-18 | ||
| PCT/JP2019/049352 WO2020129964A1 (ja) | 2018-12-18 | 2019-12-17 | ウルソデオキシコール酸を含有する老視の治療または予防剤 |
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| PCT/JP2019/049352 A-371-Of-International WO2020129964A1 (ja) | 2018-12-18 | 2019-12-17 | ウルソデオキシコール酸を含有する老視の治療または予防剤 |
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| US17/546,895 Continuation US11419880B2 (en) | 2018-12-18 | 2021-12-09 | Ursodeoxycholic acid-containing agent for treating or preventing presbyopia |
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| US20220072012A1 true US20220072012A1 (en) | 2022-03-10 |
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| US17/546,895 Active US11419880B2 (en) | 2018-12-18 | 2021-12-09 | Ursodeoxycholic acid-containing agent for treating or preventing presbyopia |
| US17/816,812 Pending US20230040386A1 (en) | 2018-12-18 | 2022-08-02 | Ursodeoxycholic acid-containing agent for treating or preventing presbyopia |
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| US17/546,895 Active US11419880B2 (en) | 2018-12-18 | 2021-12-09 | Ursodeoxycholic acid-containing agent for treating or preventing presbyopia |
| US17/816,812 Pending US20230040386A1 (en) | 2018-12-18 | 2022-08-02 | Ursodeoxycholic acid-containing agent for treating or preventing presbyopia |
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| Country | Link |
|---|---|
| US (3) | US20220072012A1 (zh) |
| EP (1) | EP3900728A4 (zh) |
| JP (2) | JP6771698B1 (zh) |
| KR (1) | KR20210105916A (zh) |
| CN (1) | CN113164499A (zh) |
| AU (1) | AU2019407391A1 (zh) |
| BR (1) | BR112021011653A2 (zh) |
| CA (1) | CA3123370A1 (zh) |
| EA (1) | EA202191684A1 (zh) |
| IL (1) | IL284004A (zh) |
| MX (1) | MX2021007161A (zh) |
| SG (1) | SG11202106216SA (zh) |
| TW (1) | TW202038966A (zh) |
| WO (1) | WO2020129964A1 (zh) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11419880B2 (en) | 2018-12-18 | 2022-08-23 | Santen Pharmaceutical Co., Ltd. | Ursodeoxycholic acid-containing agent for treating or preventing presbyopia |
| WO2022232836A1 (en) * | 2021-04-29 | 2022-11-03 | Baker Hughes Oilfield Operations Llc | Modulating pilot valve assembly |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20230145458A (ko) | 2021-02-15 | 2023-10-17 | 산텐 세이야꾸 가부시키가이샤 | 우르소데옥시콜산 또는 그 염을 함유하는 수성 의약 조성물 |
| WO2024034592A1 (ja) * | 2022-08-09 | 2024-02-15 | 参天製薬株式会社 | Ｕｄｃａまたはその塩を含有する水性医薬組成物 |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20190255074A1 (en) * | 2017-02-09 | 2019-08-22 | Yoo's Biopharm Inc. | Composition for the prevention or the treatment of visual impairments comprising ursodeoxycholic acid |
| US11419880B2 (en) * | 2018-12-18 | 2022-08-23 | Santen Pharmaceutical Co., Ltd. | Ursodeoxycholic acid-containing agent for treating or preventing presbyopia |
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| EP4082542A1 (en) * | 2009-06-15 | 2022-11-02 | Encore Health, LLC | Dithiol compounds, derivatives, and uses therefor |
| CN102178784B (zh) * | 2011-04-20 | 2013-06-12 | 威海康博尔生物药业有限公司 | 一种用于缓解视疲劳的药物组合物 |
| US9724357B2 (en) * | 2011-08-15 | 2017-08-08 | Massachusetts Eye & Ear Infirmary | Methods for preserving photoreceptor cell viability following retinal detachment |
| CN104083381A (zh) * | 2014-07-29 | 2014-10-08 | 上海中医药大学 | 熊去氧胆酸的医药用途 |
| US20170239273A1 (en) * | 2014-08-22 | 2017-08-24 | Kang Zhang | Compositions and methods to treat and/or prevent vision disorders of the lens of the eye |
| CN109364019B (zh) * | 2015-09-02 | 2021-12-28 | 盛世泰科生物医药技术(苏州)有限公司 | 一种用于预防和治疗白内障的眼用制剂及其制备方法 |
| WO2018147685A1 (ko) * | 2017-02-09 | 2018-08-16 | 주식회사 유스바이오팜 | 우르소데옥시콜산을 함유하는 시각장애 예방 또는 치료용 조성물 |
| WO2018164113A1 (ja) * | 2017-03-06 | 2018-09-13 | 学校法人 慶應義塾 | マウス近視誘導モデル及び近視予防・抑制のための小胞体ストレス抑制剤 |
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Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20190255074A1 (en) * | 2017-02-09 | 2019-08-22 | Yoo's Biopharm Inc. | Composition for the prevention or the treatment of visual impairments comprising ursodeoxycholic acid |
| US11419880B2 (en) * | 2018-12-18 | 2022-08-23 | Santen Pharmaceutical Co., Ltd. | Ursodeoxycholic acid-containing agent for treating or preventing presbyopia |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11419880B2 (en) | 2018-12-18 | 2022-08-23 | Santen Pharmaceutical Co., Ltd. | Ursodeoxycholic acid-containing agent for treating or preventing presbyopia |
| WO2022232836A1 (en) * | 2021-04-29 | 2022-11-03 | Baker Hughes Oilfield Operations Llc | Modulating pilot valve assembly |
Also Published As
| Publication number | Publication date |
|---|---|
| US11419880B2 (en) | 2022-08-23 |
| BR112021011653A2 (pt) | 2021-09-08 |
| JPWO2020129964A1 (ja) | 2021-02-15 |
| MX2021007161A (es) | 2021-10-13 |
| US20220096497A1 (en) | 2022-03-31 |
| KR20210105916A (ko) | 2021-08-27 |
| US20230040386A1 (en) | 2023-02-09 |
| CA3123370A1 (en) | 2020-06-25 |
| EA202191684A1 (ru) | 2021-09-01 |
| EP3900728A1 (en) | 2021-10-27 |
| AU2019407391A1 (en) | 2021-07-01 |
| WO2020129964A1 (ja) | 2020-06-25 |
| TW202038966A (zh) | 2020-11-01 |
| CN113164499A (zh) | 2021-07-23 |
| JP6771698B1 (ja) | 2020-10-21 |
| JP2021006548A (ja) | 2021-01-21 |
| EP3900728A4 (en) | 2022-08-17 |
| SG11202106216SA (en) | 2021-07-29 |
| IL284004A (en) | 2021-08-31 |
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