US20180284049A1 - Fluid analyzer for measuring magnesium ions and method of calibrating potentiometric magnesium ion sensor therein - Google Patents

Fluid analyzer for measuring magnesium ions and method of calibrating potentiometric magnesium ion sensor therein Download PDF

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Publication number
US20180284049A1
US20180284049A1 US15/762,892 US201615762892A US2018284049A1 US 20180284049 A1 US20180284049 A1 US 20180284049A1 US 201615762892 A US201615762892 A US 201615762892A US 2018284049 A1 US2018284049 A1 US 2018284049A1
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Prior art keywords
calibration
ion selective
selective electrode
reagents
information
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Abandoned
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US15/762,892
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English (en)
Inventor
Wei Zhang
Brian Holman
Kevin Horan
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Siemens Healthcare Diagnostics Inc
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Siemens Healthcare Diagnostics Inc
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Priority to US15/762,892 priority Critical patent/US20180284049A1/en
Assigned to SIEMENS HEALTHCARE DIAGNOSTICS INC. reassignment SIEMENS HEALTHCARE DIAGNOSTICS INC. ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: HOLMAN, BRIAN, HORAN, KEVIN, ZHANG, WEI
Publication of US20180284049A1 publication Critical patent/US20180284049A1/en
Abandoned legal-status Critical Current

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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/28—Electrolytic cell components
    • G01N27/30—Electrodes, e.g. test electrodes; Half-cells
    • G01N27/333—Ion-selective electrodes or membranes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/25—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving enzymes not classifiable in groups C12Q1/26 - C12Q1/66
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/28—Electrolytic cell components
    • G01N27/30—Electrodes, e.g. test electrodes; Half-cells
    • G01N27/301—Reference electrodes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/416—Systems
    • G01N27/4163—Systems checking the operation of, or calibrating, the measuring apparatus
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/487—Physical analysis of biological material of liquid biological material
    • G01N33/49—Blood
    • G01N33/4915—Blood using flow cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/84—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving inorganic compounds or pH

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Hematology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Urology & Nephrology (AREA)
  • Organic Chemistry (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Electrochemistry (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • Cell Biology (AREA)
  • Inorganic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Ecology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
US15/762,892 2015-09-30 2016-09-29 Fluid analyzer for measuring magnesium ions and method of calibrating potentiometric magnesium ion sensor therein Abandoned US20180284049A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
US15/762,892 US20180284049A1 (en) 2015-09-30 2016-09-29 Fluid analyzer for measuring magnesium ions and method of calibrating potentiometric magnesium ion sensor therein

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562235006P 2015-09-30 2015-09-30
PCT/US2016/054385 WO2017059037A1 (fr) 2015-09-30 2016-09-29 Analyseur de fluide pour mesurer des ions de magnésium et procédé d'étalonnage de capteur potentiométrique d'ions de magnésium à l'intérieur de celui-ci
US15/762,892 US20180284049A1 (en) 2015-09-30 2016-09-29 Fluid analyzer for measuring magnesium ions and method of calibrating potentiometric magnesium ion sensor therein

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2016/054385 A-371-Of-International WO2017059037A1 (fr) 2015-09-30 2016-09-29 Analyseur de fluide pour mesurer des ions de magnésium et procédé d'étalonnage de capteur potentiométrique d'ions de magnésium à l'intérieur de celui-ci

Related Child Applications (1)

Application Number Title Priority Date Filing Date
US16/924,898 Division US11549905B2 (en) 2015-09-30 2020-07-09 Fluid analyzer for measuring magnesium ions and method of calibrating potentiometric magnesium ion sensor therein

Publications (1)

Publication Number Publication Date
US20180284049A1 true US20180284049A1 (en) 2018-10-04

Family

ID=58427916

Family Applications (3)

Application Number Title Priority Date Filing Date
US15/762,892 Abandoned US20180284049A1 (en) 2015-09-30 2016-09-29 Fluid analyzer for measuring magnesium ions and method of calibrating potentiometric magnesium ion sensor therein
US16/924,898 Active 2037-10-04 US11549905B2 (en) 2015-09-30 2020-07-09 Fluid analyzer for measuring magnesium ions and method of calibrating potentiometric magnesium ion sensor therein
US18/061,128 Active US11782012B2 (en) 2015-09-30 2022-12-02 Fluid analyzer for measuring magnesium ions and method of calibrating potentiometric magnesium ion sensor therein

Family Applications After (2)

Application Number Title Priority Date Filing Date
US16/924,898 Active 2037-10-04 US11549905B2 (en) 2015-09-30 2020-07-09 Fluid analyzer for measuring magnesium ions and method of calibrating potentiometric magnesium ion sensor therein
US18/061,128 Active US11782012B2 (en) 2015-09-30 2022-12-02 Fluid analyzer for measuring magnesium ions and method of calibrating potentiometric magnesium ion sensor therein

Country Status (7)

Country Link
US (3) US20180284049A1 (fr)
EP (1) EP3356810A4 (fr)
JP (1) JP6888872B2 (fr)
CA (1) CA2999995C (fr)
IL (1) IL257979B (fr)
MX (1) MX2018003758A (fr)
WO (1) WO2017059037A1 (fr)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20200256821A1 (en) * 2018-02-23 2020-08-13 Hitachi High-Tech Corporation Automated analyzer and automatic analysis method
WO2020251848A1 (fr) * 2019-06-12 2020-12-17 Siemens Healthcare Diagnostics Inc. Système et procédé de mesure et d'étalonnage de test d'analyte
WO2024040052A1 (fr) * 2022-08-19 2024-02-22 Siemens Healthcare Diagnostics Inc. Procédé de détection d'une obstruction dans un analyseur de fluide

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3537153A1 (fr) * 2018-03-05 2019-09-11 Fuhrmann, Gerda Laura Moyens pour la détermination quantitative de la concentration d'un analyte dans un échantillon d'urine d'un patient
EP3640633A1 (fr) 2018-10-16 2020-04-22 UriSalt GmbH Moyens pour la détermination quantitative de la concentration d'électrolyte cationique et la concentration de créatinine et de leurs rapports
DE102018218045A1 (de) * 2018-10-22 2020-04-23 Robert Bosch Gmbh Fortgeschrittene potentiometrie für einen rekalibrierungsfreien ionenselektiven elektrodensensor

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5580441A (en) * 1993-12-16 1996-12-03 Kabushiki Kaisha Toshiba Method of measuring ion concentration and apparatus therefor
US6438501B1 (en) * 1998-12-28 2002-08-20 Battele Memorial Institute Flow through electrode with automated calibration
US10139362B2 (en) * 2011-08-01 2018-11-27 Omron Healthcare Co., Ltd. Sensor head, electrochemical sensor, and method for using electrochemical sensor

Family Cites Families (12)

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Publication number Priority date Publication date Assignee Title
US3960497A (en) * 1975-08-19 1976-06-01 Beckman Instruments, Inc. Chemical analyzer with automatic calibration
JPS5459199A (en) * 1977-10-20 1979-05-12 Olympus Optical Co Ltd Ion concentration measuring apparatus
JPH01244356A (ja) * 1988-03-25 1989-09-28 Toyota Central Res & Dev Lab Inc イオン活量の測定方法および装置
JPH07167818A (ja) * 1993-12-16 1995-07-04 Toshiba Corp イオン濃度測定装置
US6872297B2 (en) * 2001-05-31 2005-03-29 Instrumentation Laboratory Company Analytical instruments, biosensors and methods thereof
ES2355333T3 (es) 2001-08-22 2011-03-24 Instrumentation Laboratory Company Método y aparato para calibrar sensores .
ATE485507T1 (de) 2002-10-30 2010-11-15 Radiometer Medical Aps Verfahren zur durchführung der kalibration und qualitätskontrolle eines sensors und vorrichtung zur durchführung des verfahrens
JP2010501842A (ja) * 2005-08-24 2010-01-21 テレケミストリー オサケユキチュア 液体サンプルのテスト方法、テスト装置および複数のテスト装置の自動化システム
WO2008141243A2 (fr) * 2007-05-10 2008-11-20 Glumetrics, Inc. Dispositif et procédés de calibrage de détecteurs d'analytes
JP5331669B2 (ja) * 2009-12-08 2013-10-30 株式会社日立ハイテクノロジーズ 電解質分析装置
GB2503698A (en) * 2012-07-04 2014-01-08 Sphere Medical Ltd Sensor multi-point calibration method and apparatus
US20140132274A1 (en) 2012-11-13 2014-05-15 Awareness Technology Inc. Method and apparatus for providing information in an electrolyte measurment system

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5580441A (en) * 1993-12-16 1996-12-03 Kabushiki Kaisha Toshiba Method of measuring ion concentration and apparatus therefor
US6438501B1 (en) * 1998-12-28 2002-08-20 Battele Memorial Institute Flow through electrode with automated calibration
US10139362B2 (en) * 2011-08-01 2018-11-27 Omron Healthcare Co., Ltd. Sensor head, electrochemical sensor, and method for using electrochemical sensor

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20200256821A1 (en) * 2018-02-23 2020-08-13 Hitachi High-Tech Corporation Automated analyzer and automatic analysis method
WO2020251848A1 (fr) * 2019-06-12 2020-12-17 Siemens Healthcare Diagnostics Inc. Système et procédé de mesure et d'étalonnage de test d'analyte
WO2024040052A1 (fr) * 2022-08-19 2024-02-22 Siemens Healthcare Diagnostics Inc. Procédé de détection d'une obstruction dans un analyseur de fluide

Also Published As

Publication number Publication date
EP3356810A4 (fr) 2018-10-31
MX2018003758A (es) 2018-09-12
EP3356810A1 (fr) 2018-08-08
US20200340939A1 (en) 2020-10-29
IL257979B (en) 2021-12-01
US11782012B2 (en) 2023-10-10
CA2999995A1 (fr) 2017-04-06
IL257979A (en) 2018-05-31
US11549905B2 (en) 2023-01-10
WO2017059037A1 (fr) 2017-04-06
US20230104001A1 (en) 2023-04-06
JP6888872B2 (ja) 2021-06-16
CA2999995C (fr) 2021-08-24
JP2018529964A (ja) 2018-10-11

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