US20120277254A1 - Inhibitors of bruton's tyrosine kinase - Google Patents

Inhibitors of bruton's tyrosine kinase Download PDF

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Publication number
US20120277254A1
US20120277254A1 US13/542,440 US201213542440A US2012277254A1 US 20120277254 A1 US20120277254 A1 US 20120277254A1 US 201213542440 A US201213542440 A US 201213542440A US 2012277254 A1 US2012277254 A1 US 2012277254A1
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United States
Prior art keywords
substituted
alkyl
unsubstituted
compound
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
US13/542,440
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US8754091B2 (en
Inventor
Lee Honigberg
Erik Verner
Zhengying Pan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pharmacyclics LLC
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Pharmacyclics LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
Priority to US82672006P priority Critical
Priority to US82859006P priority
Priority to US11/617,645 priority patent/US7514444B2/en
Priority to US12/356,498 priority patent/US8088781B2/en
Priority to US13/249,066 priority patent/US8735403B2/en
Priority to US13/312,606 priority patent/US8497277B2/en
Priority to US13/328,718 priority patent/US8476284B2/en
Priority to US13/335,719 priority patent/US8735404B2/en
Priority to US13/340,556 priority patent/US8741908B2/en
Priority to US13/340,409 priority patent/US8748438B2/en
Priority to US13/361,733 priority patent/US8399470B2/en
Priority to US13/450,158 priority patent/US8748439B2/en
Priority to US13/472,292 priority patent/US8691546B2/en
Priority to US13/479,053 priority patent/US8697711B2/en
Priority to US13/542,440 priority patent/US8754091B2/en
Application filed by Pharmacyclics LLC filed Critical Pharmacyclics LLC
Assigned to PHARMACYCLICS, INC. reassignment PHARMACYCLICS, INC. ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: PAN, ZHENGYING, VERNER, ERIK, HONIGBERG, LEE
Publication of US20120277254A1 publication Critical patent/US20120277254A1/en
Application granted granted Critical
Publication of US8754091B2 publication Critical patent/US8754091B2/en
Assigned to PHARMACYCLICS, INC. reassignment PHARMACYCLICS, INC. MERGER (SEE DOCUMENT FOR DETAILS). Assignors: OXFORD AMHERST CORPORATION
Assigned to PHARMACYCLICS LLC reassignment PHARMACYCLICS LLC MERGER AND CHANGE OF NAME (SEE DOCUMENT FOR DETAILS). Assignors: OXFORD AMHERST LLC, PHARMACYCLICS, INC.
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39225888&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=US20120277254(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Assigned to PHARMACYCLICS, INC. reassignment PHARMACYCLICS, INC. CORRECTIVE ASSIGNMENT TO CORRECT THE CONVEYING PARTY DATA PREVIOUSLY RECORDED ON REEL 036126 FRAME 0377. ASSIGNOR(S) HEREBY CONFIRMS THE MERGER. Assignors: OXFORD AMHERST CORPORATION, PHARMACYCLICS, INC.
Assigned to PHARMACYCLICS LLC reassignment PHARMACYCLICS LLC CORRECTIVE ASSIGNMENT TO CORRECT THE CONVEYING PARTY DATA PREVIOUSLY RECORDED ON REEL 036126 FRAME 0398. ASSIGNOR(S) HEREBY CONFIRMS THE MERGER AND CHANGE OF NAME. Assignors: OXFORD AMHERST LLC, PHARMACYCLICS, INC.
Application status is Active legal-status Critical
Anticipated expiration legal-status Critical

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