US20120125584A1 - Heat exchange circuit - Google Patents

Heat exchange circuit Download PDF

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Publication number
US20120125584A1
US20120125584A1 US13/388,109 US201013388109A US2012125584A1 US 20120125584 A1 US20120125584 A1 US 20120125584A1 US 201013388109 A US201013388109 A US 201013388109A US 2012125584 A1 US2012125584 A1 US 2012125584A1
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Prior art keywords
corrugations
circuit
walls
heat exchange
wall
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US13/388,109
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English (en)
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Massimo Fini
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Sis Ter SpA
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M19/00—Local anaesthesia; Hypothermia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
    • A61M1/1654—Dialysates therefor
    • A61M1/1656—Apparatus for preparing dialysates
    • A61M1/166—Heating
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/44—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests having means for cooling or heating the devices or media
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F28—HEAT EXCHANGE IN GENERAL
    • F28F—DETAILS OF HEAT-EXCHANGE AND HEAT-TRANSFER APPARATUS, OF GENERAL APPLICATION
    • F28F21/00—Constructions of heat-exchange apparatus characterised by the selection of particular materials
    • F28F21/06—Constructions of heat-exchange apparatus characterised by the selection of particular materials of plastics material
    • F28F21/065—Constructions of heat-exchange apparatus characterised by the selection of particular materials of plastics material the heat-exchange apparatus employing plate-like or laminated conduits
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F28—HEAT EXCHANGE IN GENERAL
    • F28F—DETAILS OF HEAT-EXCHANGE AND HEAT-TRANSFER APPARATUS, OF GENERAL APPLICATION
    • F28F3/00—Plate-like or laminated elements; Assemblies of plate-like or laminated elements
    • F28F3/02—Elements or assemblies thereof with means for increasing heat-transfer area, e.g. with fins, with recesses, with corrugations
    • F28F3/04—Elements or assemblies thereof with means for increasing heat-transfer area, e.g. with fins, with recesses, with corrugations the means being integral with the element
    • F28F3/042—Elements or assemblies thereof with means for increasing heat-transfer area, e.g. with fins, with recesses, with corrugations the means being integral with the element in the form of local deformations of the element
    • F28F3/046—Elements or assemblies thereof with means for increasing heat-transfer area, e.g. with fins, with recesses, with corrugations the means being integral with the element in the form of local deformations of the element the deformations being linear, e.g. corrugations
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F28—HEAT EXCHANGE IN GENERAL
    • F28F—DETAILS OF HEAT-EXCHANGE AND HEAT-TRANSFER APPARATUS, OF GENERAL APPLICATION
    • F28F3/00—Plate-like or laminated elements; Assemblies of plate-like or laminated elements
    • F28F3/12—Elements constructed in the shape of a hollow panel, e.g. with channels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/12—General characteristics of the apparatus with interchangeable cassettes forming partially or totally the fluid circuit
    • A61M2205/127—General characteristics of the apparatus with interchangeable cassettes forming partially or totally the fluid circuit with provisions for heating or cooling
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/36—General characteristics of the apparatus related to heating or cooling
    • A61M2205/3653—General characteristics of the apparatus related to heating or cooling by Joule effect, i.e. electric resistance
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/36—General characteristics of the apparatus related to heating or cooling
    • A61M2205/3673—General characteristics of the apparatus related to heating or cooling thermo-electric, e.g. Peltier effect, thermocouples, semi-conductors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2206/00—Characteristics of a physical parameter; associated device therefor
    • A61M2206/10—Flow characteristics
    • A61M2206/20—Flow characteristics having means for promoting or enhancing the flow, actively or passively
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T29/00—Metal working
    • Y10T29/49—Method of mechanical manufacture
    • Y10T29/4935—Heat exchanger or boiler making

Definitions

  • the invention relates to a circuit for heat exchange to/from a liquid, in particular for heat exchange between a device and a liquid or between two liquids. Even more particularly, the invention relates to a disposable circuit for heat exchange to/from a physiological liquid. The invention relates moreover to the thermal device suitable for use together with the disposable circuit.
  • the liquid In some cases it is necessary for the liquid to be heated before infusion, in order to avoid the risk of inducing an undesirable state of hypothermia in the patient. In such cases, the temperature of the liquid, which is typically blood or an infusion liquid, must be as close as possible to the physiological body temperature of the patient.
  • hypothermia In other cases, such as for example certain surgical operations, a controlled state of hypothermia must be induced in the patient.
  • By artificially lowering the body temperature of the patient it is in fact possible to slow down the metabolic processes of the organism so as to reduce the oxygen intake. In this way, it is possible to suspend circulation of the blood for relatively long periods of time and thereby prevent the lack of blood flow and consequent hypoxia from causing damage to the tissues.
  • hypothermia achieved by lowering the patient's temperature to about 20° C., allows complete stoppage of the blood circulation for periods of about 30 minutes.
  • hypothermia usually hypothermia of average intensity (about 28 to 32° C.) is induced to ensure optimum protection of the tissues, in particular the brain tissues.
  • hypothermia is induced by externally cooling the patient, but in particular cooling the blood using special heat exchangers able to extract heat from the blood. At the end of the operation it is obviously required to raise the patient's temperature back to the physiological values; heating of the blood is usually performed using the same extracorporeal circuit, but with the heat being transferred to the blood, instead of being extracted from it.
  • Heating the blood is necessary in the event of major transfusions and/or in cases where the transfusion is not programmed and there is not enough time to prepare the bags and heat them to room temperature.
  • the main defect of the known circuits is the general low level of heat exchange efficiency. Heat exchange must be performed in real time along the line used to convey the physiological liquid. Poor efficiency means slowing down of the infusion operation and/or the need to ensure that greater quantities of liquid are present inside the exchanger (priming).
  • the object of the present invention is therefore to solve at least partially the drawbacks identified in connection with the heat exchange circuits of the known type.
  • the aim of the present invention is to provide a heat exchange circuit which has a high efficiency.
  • the aim of the present invention is to provide a heat exchange circuit which has a simple design and low cost.
  • FIG. 1 shows schematically two walls suitable for forming a heat exchange circuit according to the invention
  • FIG. 2 shows schematically the two walls according to FIG. 1 in a different configuration
  • FIG. 3 shows schematically a side view of a heat exchange circuit according to the invention
  • FIG. 4 . a shows schematically the pattern in the first wall of a heat exchange circuit according to the invention
  • FIG. 4 . b shows schematically the pattern of a second wall of a heat exchange circuit according to the invention
  • FIG. 4 . c shows schematically the superimposed arrangement of the patterns according to FIGS. 4 . a and 4 . b;
  • FIG. 5 shows a heat exchange circuit according to the invention, viewed in cross-section along the line V-V of FIG. 4 . c;
  • FIG. 6 shows a heat exchange circuit according to the invention, viewed in cross-section along the line VI-VI of FIG. 4 . c;
  • FIG. 7 shows schematically a perspective view of a heat exchange circuit according to the invention, similar to that of FIG. 3 ;
  • FIG. 8 shows schematically a plan view of the thermal device according to the invention, with the lid raised
  • FIG. 9 shows schematically a plan view of an assembly consisting of a heat exchange circuit of the type shown in FIG. 3 and the thermal device according to FIG. 8 ;
  • FIG. 10 shows schematically a side view of the assembly according to FIG. 9 ;
  • FIG. 11 shows schematically a cross-sectional view of the assembly according to FIG. 9 ;
  • FIG. 12 shows schematically a plan view of a heat exchange circuit according to the invention.
  • FIG. 13 shows schematically a side view of the heat exchange circuit according to FIG. 12 ;
  • FIG. 14 shows schematically a plan view of an assembly consisting of a heat exchange circuit of the type shown in FIG. 12 and a thermal device according to the invention
  • FIG. 15 shows schematically a side view of the assembly according to FIG. 14 ;
  • FIG. 16 shows schematically a cross-sectional view of the assembly according to FIG. 14 in two different configurations
  • FIG. 17 shows schematically a side view of a heat exchange circuit according to the invention.
  • FIG. 18 shows schematically a cross-sectional view of an assembly consisting of a heat exchange circuit of the type shown in FIG. 17 and a thermal device according to the invention
  • FIG. 19 shows schematically a plan view of a heat exchange circuit according to the invention.
  • FIG. 20 shows schematically a plan view of a heat exchange circuit according to the invention
  • FIG. 21 shows schematically a plan view of a heat exchange circuit according to the invention.
  • FIG. 22 shows schematically an enlarged detail of the cross-section along the line XXII-XXII in FIG. 21 ;
  • FIG. 23 shows schematically a plan view of an assembly consisting of a heat exchange circuit of the type shown in FIG. 20 and a thermal device according to the invention
  • FIG. 24 shows schematically a plan view of an assembly consisting of a heat exchange circuit of the type shown in FIG. 21 and a thermal device according to the invention
  • FIG. 25 shows schematically a plan view of a heat exchange circuit according to the invention, partially cut-away
  • FIG. 26 shows schematically a side view of the heat exchange circuit according to FIG. 25 , partially cut-away;
  • FIG. 27 shows the device indicated by XXVII in FIG. 26 ;
  • FIG. 28 shows some possible configurations of the corrugations of the circuit according to the invention.
  • FIG. 29 . a shows a portion of a first type of wall of a heat exchange circuit according to the invention
  • FIG. 29 . b shows a portion of a second type of wall of a heat exchange circuit according to the invention
  • FIG. 29 . c shows a portion of the third type of wall of a heat exchange circuit according to the invention.
  • FIG. 30 show schematically a cross-sectional view of an assembly consisting of a heat exchange circuit and a thermal device according to the invention in two different configurations;
  • FIG. 31 show schematically a cross-sectional view of an assembly consisting of a heat exchange circuit and a thermal device according to the invention in two different configurations.
  • the present invention relates to a heat exchange circuit, indicated in its entirety by 30 .
  • the circuit 30 is designed to promote heat exchange to/from a physiological fluid and comprises at least two walls 32 and 34 which rest against each other and are sealed so as to form a duct 36 able to contain a flow of physiological fluid.
  • Each one of the at least two walls 32 and 34 comprises, during use, a pattern of corrugations 320 and 340 .
  • the corrugations have, at least along sections, a preferential direction.
  • the pattern of corrugations 320 of one wall 32 is positioned so as to be superimposed at least partially on the pattern of corrugations 340 of the other wall so as to form an angle ⁇ between the respective preferential directions, the angle ⁇ ranging between 70° and 110°.
  • at least one of the walls 32 or 34 is designed to transfer heat to/from the liquid flow.
  • FIGS. 1 and 2 show the two walls 32 and 34 before they are joined together to form the circuit 30 .
  • FIG. 1 shows the two walls 32 and 34 next to each other and arranged with the same orientation. As can be noted, they are entirely identical, even though this is not strictly necessary; each of them comprises a pattern of corrugations, 320 and 340 , respectively, and an opening 322 and 342 , respectively.
  • the walls 32 and 34 have a small thickness in relation to the amplitude of the corrugations. This means that the same pattern of corrugations appears on both sides of the wall.
  • the patterns of corrugations for example 320 and 340 , are shown as hatched areas on the surfaces of the wails.
  • the lines of the hatching may be regarded as being a schematic representation of the peaks of the corrugations or, equally well, a schematic representation of the valleys of the corrugations.
  • FIG. 2 shows the two walls 32 and 34 arranged next to each other.
  • the first wall 32 has retained the same orientation, while the second wall 34 has been rotated twice with respect to the orientation shown in FIG. 1 .
  • Said second wall has undergone a first rotation through 180° in its plane and a second rotation through 180° about its longitudinal axis X′′. It can be noted how the pattern of corrugations 340 of the wall 34 is perfectly visible also on the opposite side, owing to the fact that, in the present embodiment, the wall 34 has a small thickness in relation to the amplitude of the corrugations.
  • the two walls 32 and 34 may be arranged on top of each other so that the two corrugation patterns 320 and 340 coincide.
  • the walls are formed so that, machining tolerances excluded, the two corrugation patterns are superimposed perfectly on top of each other.
  • FIG. 2 shows for each one of the two walls 32 and 34 preferential directions of the corrugations. More specifically, the pattern 320 has a preferential direction which forms an angle ⁇ with the longitudinal axis X′ of the wall 32 , while the pattern 340 has a preferential direction which forms an angle ⁇ with the longitudinal axis X′′ of the wall 34 .
  • ⁇ and ⁇ are the same angle conventionally attributed an opposite sign. However, in other embodiments, there is nothing to prevent ⁇ and ⁇ being different from each other in terms of absolute values.
  • the amplitude of ⁇ and ⁇ is substantially equal to 45°. This value represents an excellent compromise between conflicting design requirements: on the one hand it is opportune to limit the head losses in the circuit 30 , while on the other hand it is required to ensure a high degree of mixing inside the fluid. The first requirement would lead to a reduction in the amplitude of the angles ⁇ and ⁇ to about 30°, while the second requirement would increase it to about 60°. In practice, specific tests carried out by the Applicant have shown how angles ⁇ and ⁇ with an amplitude of between 35° and 55° ensure limited head losses and optimum mixing.
  • the angle ⁇ formed between the two preferential directions of the two corrugation patterns is defined by the sum of the amplitudes ⁇ and ⁇ . In the specific case, therefore, the angle ⁇ has an amplitude equal to about 90°, while in other embodiments of the invention it may vary between 70° and 110°.
  • FIG. 3 shows a side view of a circuit 30 according to the invention. It is obtained by superimposing the walls 32 and 34 (in the configuration shown in FIG. 2 ) and welding them along the periphery 40 .
  • FIG. 3 it can also be seen how the longitudinal axis X′ of the wall 32 and the longitudinal axis X′′ of the wall 34 are superimposed on each other to form the longitudinal axis X of the circuit 30 .
  • FIG. 7 shows a perspective view of a circuit 30 according to the invention, similar to that shown in FIG. 3 .
  • the circuit 30 comprises two openings 322 and 342 .
  • the opening 322 will be regarded as an inlet and the opening 342 as an outlet. Obviously nothing would change if the functions of the two openings were assumed to be reversed.
  • FIG. 4 shows in a very simplified form the preferential directions of the corrugations of the two walls considered individually (FIGS. 4 . a and 4 . b ) and the two walls superimposed (FIG. 4 . c ).
  • This illustration shows furthermore the relationship between the angles ⁇ , ⁇ and ⁇ .
  • FIG. 4 . c shows by way of explanation two different cross-sectional lines.
  • the line VI-VI divides the grid pattern of corrugations along a contact line between the respective peaks, while the line V-V divides the grid pattern along a line where there is no contact.
  • the cross-sections obtained along these lines are shown schematically in the following FIGS. 5 and 6 .
  • FIGS. 5 and 6 These figures are shown in perspective so as to illustrate more clearly the layout of the network of channels formed by the combination of the two corrugation patterns 320 and 340 .
  • FIG. 8 shows a thermal device according to the invention, denoted in its entirety by 50 .
  • the thermal device 50 is designed to cooperate with the heat exchange circuit 30 and comprises two plates 52 and 54 , at least one of which is thermally active.
  • the plates 52 and 54 are shaped so as to ensure intimate contact with the walls 32 and 34 of the circuit 30 at least in the zones coinciding with the respective corrugation patterns 320 and 340 .
  • the thermal device 50 comprises a base, comprising the plate 52 , and a lid which can be opened and closed onto the base and which comprises the plate 54 . Both the plates 52 and 54 are thermally active.
  • a circuit of the type shown in FIG. 7 may be arranged between the lid and the base.
  • FIGS. 9 and 10 show the assembly consisting of the heat exchange circuit 30 according to FIG. 7 inserted inside the thermal device according to FIG. 8 .
  • the inlet 322 and the outlet 342 of the circuit 30 inserted inside the thermal device 50 are perfectly accessible and able to be used.
  • the liquid may be supplied to the circuit 30 and may be drawn off after heat exchange without the positioning of the circuit 30 inside the thermal device 50 having any effect on the circulation of the liquid.
  • the plate 52 comprises a pattern of corrugations 520 identical to the pattern 320 of the wall 32 with which it is intended to come into contact. As a result it is possible to ensure intimate contact between the wall 32 of the circuit 30 and the thermally active plate 52 . The same intimate contact is similarly achieved also between the wall 34 and the plate 54 .
  • FIG. 11 The intimate contact between the two corrugation patterns is illustrated in the schematic cross-section shown in FIG. 11 .
  • This cross-section and all the following cross-sections have been simplified for greater clarity.
  • the cross-section in FIG. 11 does not show the perspective layout of the network of channels formed by the corrugations; for this layout reference should be made again to FIGS. 5 and 6 .
  • FIG. 11 shows, instead, the intimate contact between the patterns, i.e. shows how the corrugations of the plates 52 and 54 match perfectly the outer corrugations of the walls 32 and 34 .
  • the peaks of the corrugations of the plates 52 and 54 fit perfectly inside the peaks of the corrugations of the walls 32 and 34 , respectively, and also how the valleys of the corrugations in the plates 52 and 54 fit perfectly inside the valleys of the corrugations in the walls 32 and 34 , respectively.
  • the intimate contact between the corrugation patterns ensures that the walls 32 and 34 rest fully on the thermally active plates 52 and 54 , so as to prevent the presence of air between the walls and the plates. Air is in fact not a good heat conductor and its presence between the walls and the plates would adversely affect the heat exchange efficiency.
  • FIGS. 11 , 16 , 18 , 30 and 31 for greater clarity, the walls 32 and 34 are shown slightly spaced from the respective plates 52 and 54 , but in reality this spacing is not present.
  • At least one of the plates 52 and 54 is defined here as being thermally active. It is in fact able to assume a temperature different from the external temperature of the walls of the circuit 30 . More specifically, according to certain embodiments, the thermally active plate 52 or 54 may assume higher temperatures so as to release heat to the walls of the circuit 30 . According to other embodiments, the thermally active plate 52 or 54 may assume lower temperatures so as to absorb heat from the walls of the circuit 30 . According to further other embodiments, the thermally active plate 52 or 54 may assume higher or alternatively lower temperatures so as to release or alternatively absorb heat to/from the walls of the circuit 30 .
  • the temperature of the thermally active plate 52 or 54 can be preferably regulated via suitable regulating means 53 .
  • only one of the two plates 52 and 54 is thermally active, while in other embodiments both of them are active.
  • the plates 52 and/or 54 may comprise different means for rendering them thermally active. These means may consist of electric resistors which are designed to raise the temperature, or Peltier cells, which are able both to raise the temperature and, by reversing the polarity of the power supply, to lower it.
  • the walls 32 and 34 may be made of polymer material or metallic material. These materials must be suitable for retaining the form imparted to them during production, especially as regards the corrugations.
  • a stable form of the corrugations in fact ensures intimate contact between the walls of the circuit 30 and the plates of the thermal device 50 . If, however, the corrugations should be deformed, this intimate contact would be affected, air would enter between the walls, and the plates and the heat exchange efficiency would be drastically reduced.
  • the walls must have a particularly small thickness in order to compensate for the fairly low thermal conductivity which is typical of the polymers.
  • the thermal conductivity of the polymer may be increased by means of the addition of suitable fillers dispersed in the polymer itself. These fillers may be, for example, in a manner known per, metal and/or ceramic particles.
  • suitable fillers may be, for example, in a manner known per, metal and/or ceramic particles.
  • a metallic material is used for the walls 32 and 34 , this may be chosen, for example, from aluminium, titanium and stainless steel.
  • the walls made of metallic material could if necessary comprise a thin polymer lining should it be required to improve the biocompatibility thereof or other desirable characteristics such as the resistance to corrosion and/or to aggressive chemical agents.
  • the thickness s of the polymer walls advantageously ranges between 30 and 300 ⁇ m, while the thickness of the metal walls advantageously ranges between 100 and 200 ⁇ m.
  • the thickness of the corrugations (or wave amplitude ⁇ ) advantageously ranges between 500 and 3000 ⁇ m.
  • FIGS. 12 to 16 show a different embodiment of the heat exchange circuit 30 and, consequently, the associated thermal device 50 .
  • the heat exchange circuit 30 shown in FIGS. 12 and 13 comprises two smooth walls 32 and 34 , i.e. without the corrugation patterns described above. With the sole exception of the corrugations not present, the heat exchange circuit 30 has a form similar to that of the preceding figures.
  • the thermal device 50 according to FIGS. 14 to 16 is similar to that described above, but comprises plates which, in addition to being thermally active, also have a suction function. As can be noted in the schematic cross-section in FIG. 16 . a , the thermal device encloses internally the circuit 30 with the smooth wails, as shown in FIGS. 12 and 13 .
  • the plates 52 and 54 of the thermal device 50 comprise corrugation patterns 520 and 540 , respectively, which are substantially similar to those described above.
  • the plates 52 and 54 also comprise suction conduits 58 which are connected to the vacuum application means 56 of the thermal device 50 .
  • suction conduits 58 which are connected to the vacuum application means 56 of the thermal device 50 .
  • the walls 32 and 34 may be made to adhere fully against the plates 52 and 54 so as to reproduce exactly the corrugations thereof.
  • the final configuration of the walls 32 and 34 in intimate contact with the plates 52 and 54 is schematically shown in FIG. 16 . b .
  • the walls 32 and 34 are slightly spaced from the plates 52 and 54 for greater clarity, but in reality this spacing is not present and on the contrary contact is forcibly provided by means of the action of the vacuum.
  • the suction conduits 58 are preferably arranged in arrays on the bottom of the valleys of the corrugations of the plates 52 and 54 . This arrangement of the suction conduits 58 is shown in FIG. 16 .
  • the plates 52 and 54 are made of porous material which is obtained for example by means of sintering of metal powders of suitable particle size.
  • the porous plates 52 and 54 allow widespread suction of the air trapped between the walls 32 and 34 and therefore without the presence of the suction conduits 58 .
  • the walls 32 and 34 must necessarily be deformable so as to be able to reproduce accurately, during use, the corrugation patterns of the suction plates 52 and 54 .
  • the circuit 30 is made of polymer material
  • deformation of the walls 32 and 34 may to a large extent consist of an elastic deformation. Therefore, when the vacuum is no longer applied, the corrugations become almost entirely flat.
  • deformation of the walls 32 and 34 to a large extent consists of a plastic deformation. Therefore, even when the vacuum is no longer applied, the corrugations remain substantially unaffected.
  • FIGS. 17 and 18 is a mixed form where the wall 32 is preformed so as to comprise the patterns of corrugations 320 as well as the walls of the circuit 30 shown in FIGS. 1 to 11 .
  • the wall 34 is smooth and must be corrugated at the time of use, as must be the walls of the circuit 30 according to FIGS. 12 to 16 .
  • FIG. 18 shows schematically a cross-sectional view of the assembly consisting of the circuit 30 according to FIG. 17 and the respective thermal device 50 .
  • the thermal device 50 comprises a plate 52 similar to that of the device 50 according to FIGS. 8 to 11 and the other plate 54 similar to the device 50 according to FIGS. 14 to 16 .
  • the walls 32 and 34 may be made of materials different from each other.
  • FIG. 19 shows a heat exchange circuit 30 similar to that of FIGS. 1 to 11 in which, however, the preferential direction of the corrugations may be defined solely along sections within the patterns 320 and 340 .
  • the corrugations define four different homogeneous areas, i.e. each with a well defined preferential direction. According to other possible embodiments it is possible for the homogeneous areas to be present in a different number and/or arrangement. It has been noted, during specific tests carried out by the Applicant, that the transition between two adjacent homogeneous areas, with a consequent change in preferential direction, results in substantial advantages in terms of mixing inside the flow.
  • FIG. 20 shows a different embodiment of the circuit 30 according to the invention.
  • the two walls 32 and 34 are sealed with respect to each other not only along the periphery, but also partially along the centre line 42 .
  • the circuit 30 has a substantially U-shaped extension in which the inlet 322 and the outlet 342 are adjacent to each other.
  • FIG. 21 shows an embodiment which is similar to that of FIG. 20 , but in which the U-shaped circuit 30 also comprises a top pipe 38 which is relatively rigid with respect to the walls 32 and 34 .
  • the top pipe 38 defines the inlet 322 and the outlet 342 of the U-shaped circuit 30 .
  • the internal channel of the top pipe 38 is interrupted so that the liquid is forced to pass through the side openings 380 which allow it to flow into and out of the duct 36 .
  • FIG. 22 shows in detail the cross-section of the circuit 30 according to FIG. 21 at the point where the top pipe 38 is joined to the walls 32 and 34 .
  • FIGS. 20 and 21 show both the U-shaped 30 circuits in embodiments in which the walls comprise preformed corrugations.
  • This illustration makes it easier to understand how the corrugations may be arranged and how they are able to define a common preferential direction along the entire U-shaped circuit.
  • the axis X of the entire circuit relative to which the angles ⁇ and ⁇ of the preferential directions of the corrugations are defined, is not readily definable.
  • the possibility of determining the angle ⁇ , defined by the preferential directions of the two superimposed patterns of corrugations obviously remains unchanged.
  • U-shaped circuits it is perfectly possible, in other embodiments, for the abovementioned U-shaped circuits to be formed with smooth walls, such as those described in relation to the circuit 30 of FIGS. 13 to 16 , or with mixed walls, such as those described in relation to the circuit 30 according to FIGS. 17 and 18 .
  • FIGS. 23 and 24 shows two assemblies according to the invention. They comprise U-shaped circuits, according to the embodiments shown in FIGS. 20 and 21 , respectively, and the corresponding thermal devices 50 associated with them.
  • the respective thermal devices 50 must also comprise the vacuum application means 56 such as those described above in connection with FIGS. 14 to 16 and 18 .
  • FIGS. 25 to 27 show a different embodiment of the heat exchange circuit according to the invention.
  • the circuit comprises three walls 32 , 33 and 34 so as to define two different ducts 36 ′ and 36 ′′ which are separate from each other.
  • the outer walls 32 and 34 of the circuit 30 each define two openings. It is thus possible to define an inlet 322 and an outlet 324 for the duct 36 ′ and an inlet 344 and an outlet 342 for the duct 36 ′′.
  • This type of heat exchange circuit 30 is not intended to co-operate with a thermal device 50 , but is instead intended to be used as an exchanger of heat between two different liquid flows at different temperatures.
  • the heat exchange circuit 30 according to FIGS. 25 to 27 also comprises corrugation patterns similar to those of the other embodiments described above.
  • the corrugation patterns in this case are three in number, one for each wall 32 , 33 and 34 .
  • the outer walls 32 and 34 have a large thickness in relation to the amplitude of the corrugations.
  • the corrugations may be maintained only on the inside of the circuit, while the outer surfaces of the circuit may be smooth.
  • the inner wall 33 has a small thickness in relation to the amplitude of the corrugations such that the same corrugation pattern appears on both sides of the wall itself.
  • the outer walls 32 and 34 are intended to prevent as far as possible heat exchange between the inside of the circuit and the surrounding environment. For this reason, the outer walls 32 and 34 have a large thickness and are preferably made of polymer material with a low thermal conductivity coefficient.
  • the inner wall 33 is intended to facilitate as far as possible heat exchange between the two ducts 36 ′ and 36 ′′. For this reason, the inner wall 33 has a small thickness and is preferably made of metallic material with a high thermal conductivity coefficient.
  • FIGS. 29 . a and 29 . b show schematically two wall portions, which are respectively thin and thick, with the same type of corrugation.
  • FIGS. 29 . b and 29 . c show schematically wall portions, which are both thick, with different types of corrugation.
  • the heat exchange circuits 30 reference has always been made to walls with a small thickness, with the sole exception of the outer walls 32 and 34 of the circuit shown in FIGS. 25 to 27 .
  • the circuit 30 comprises a thick wall 32 in which the corrugations appear on the inner side only, while the outer side is smooth.
  • the thick wall is preferably made of metallic material. Indeed, as already mentioned above, metallic materials have high thermal conductivity and thus allow the use of large wall thicknesses.
  • the thermal devices 50 designed to cooperate with these embodiments of the circuit 30 have thermally active plates with a smooth surface. The smooth plates ensure that the desired intimate contact with the externally smooth walls of the circuit 30 is obtained.
  • the wall 34 is of the thin and smooth type, but there is nothing to prevent it from being one of the other types described here.
  • the wall 32 is preformed so as to comprise the pattern of corrugations 320 , like the walls of the circuit 30 according to FIGS. 1 to 11 .
  • the wall 34 is smooth and must be corrugated at the time of use. Differently from that shown in FIGS. 16 , 18 and 30 , however, in this case the formation of the corrugations is not performed by the application of the vacuum from the outside.
  • the corrugations of the wall 34 are obtained as a result of internal pressure of the fluid which presses the wall 34 against the plate 54 . The effect of this pressure is schematically indicated by means of the dotted-line arrows in FIG. 31 . b .
  • the figure shows corrugations with a wave amplitude ⁇ which is smaller for the wall 34 than that of the corrugations preformed on the wall 32 .
  • the walls 32 and 34 may be made of materials and/or with thicknesses which are different from each other.
  • the corrugations have a configuration which is substantially comparable to a sinusoid of given amplitude and wavelength. According to other embodiments, however, the progression may be of a different nature. Some configurations are shown by way of example in FIG. 28 .
  • FIG. 28 . a shows the substantially sinusoidal progression of the embodiments described above.
  • FIG. 28 . b shows a broken-line progression in which straight sections are connected together by sharp angles. This configuration would be optimal from the point of view of the mixing which could be induced in the flow, but in most cases with the technologies for forming such corrugations it is not possible to obtain a sharp angle.
  • FIG. 28 . c shows a broken-line configuration in which straight sections are connected together by curved portions.
  • FIG. 28 . d shows a combined sinusoidal/broken line configuration.
  • FIG. 28 . e shows a configuration in which the wavelength of the corrugations is not constant along the length of the pattern.
  • FIG. 28 . f shows instead a further configuration in which the amplitude of the corrugations is not constant along the length of the patterns.
  • the configuration is sinusoidal, but of course a variation of wavelength and/or amplitude may also be obtained for other configurations, for example of the broken line or mixed type.
  • FIG. 28 . h shows a configuration in which a square wave defines channels with a quadrangular cross-section, on both sides of the corrugations.
  • all the configurations shown by way of example, including the configuration with a variable wave amplitude, define a plane of peaks (indicated by the line ⁇ in FIG. 28 . f ), at least on one side of the pattern.
  • the presence of such a plane is highly advantageous for being able to define a support surface against another wall and for being able to define a circuit according to the invention.
  • the particular internal configuration of the circuit 30 according to the invention is able to achieve a high heat exchange efficiency.
  • the arrangement of the corrugation patterns on top of each produces a network of channels which form a duct 36 in which the flow of liquid has a minimum thickness.
  • the minimum thickness of the flow allows minimization of the thermal boundary layer effect, this effect resulting in large temperature differences between the layer of liquid directly in contact with the wall and the layers situated within the flow and at a distance from the wall.
  • the thermal boundary layer effect thus results in the need, in low-efficiency circuits of known type, for high wall temperatures (70-80° C.) in order to compensate for the difficulty in supplying heat to the deep layers within the flow. As already mentioned in the introduction, these wall temperatures are inherently dangerous for the patient's health.
  • the particular configuration of the corrugation patterns and their arrangement on top of each other ensures intense mixing of the liquid which further limits the boundary layer effect.
  • the liquid which is in direct contact with the wall along a duct section, because of the intense mixing, will almost certainly be situated at a distance from the wall along a subsequent duct section.
  • the high degree of mixing or turbulence phenomena induced in the flow by the particular configuration of the channel network continuously mixes the liquid, preventing the possible formation of large temperature differences within it.
  • the heat exchange circuit according to the invention is extremely economical from a manufacturing point of view, being particularly suitable for use as a disposable insert.
  • many embodiments of the circuit 30 consist of two walls 32 and 34 which are identical to each other. In this respect production of the circuit 30 is greatly simplified since it is sufficient to perform pressing of a large of number of walls of a single type, with obvious advantages in logistics terms. This feature is highlighted in particular in FIGS. 1 to 3 , but is likewise also valid for the embodiments according to FIGS. 12-13 , 19 and 20 .
  • the embodiment according to FIGS. 25 to 27 although different, also benefits partly from this feature.
  • the outer walls 32 and 34 are in fact identical to each other, while the single inner wall 33 requires a different production method.

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Hematology (AREA)
  • Mechanical Engineering (AREA)
  • Thermal Sciences (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Emergency Medicine (AREA)
  • Heat-Exchange Devices With Radiators And Conduit Assemblies (AREA)
  • Non-Silver Salt Photosensitive Materials And Non-Silver Salt Photography (AREA)
US13/388,109 2009-08-03 2010-07-19 Heat exchange circuit Abandoned US20120125584A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
ITTV2009A000156A IT1399277B1 (it) 2009-08-03 2009-08-03 Circuito di scambio termico.
ITTV2009A000156 2009-08-03
PCT/IB2010/053279 WO2011015961A1 (en) 2009-08-03 2010-07-19 Heat exchange circuit

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US (1) US20120125584A1 (de)
EP (1) EP2461854B1 (de)
ES (1) ES2423057T3 (de)
IT (1) IT1399277B1 (de)
WO (1) WO2011015961A1 (de)

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20150083380A1 (en) * 2013-09-25 2015-03-26 Giuseppe BETTI Heat exchanger element of large surface
JP2016020776A (ja) * 2014-07-15 2016-02-04 国立大学法人 東京大学 熱交換器
JP2016539305A (ja) * 2013-12-05 2016-12-15 スウェップ インターナショナル アクティエボラーグ 種々のピッチを有する熱交換プレート
USD908101S1 (en) * 2018-11-26 2021-01-19 Ptt Global Chemical Public Company Limited Microchannel heat exchanger
USD908100S1 (en) * 2018-11-26 2021-01-19 Ptt Global Chemical Public Company Limited Microchannel heat exchanger
USD908644S1 (en) * 2018-11-26 2021-01-26 Ptt Global Chemical Public Company Limited Microchannel heat exchanger
US20210270545A1 (en) * 2018-06-27 2021-09-02 Welcon Inc. Heat transport device and method for manufacturing same
US20220128313A1 (en) * 2018-05-29 2022-04-28 Cooler Master Co., Ltd. Heat dissipation plate and method for manufacturing the same

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013053674A1 (en) 2011-10-13 2013-04-18 Mequ Aps An infusion fluid warmer

Citations (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US441781A (en) * 1890-12-02 teeisen
US1966133A (en) * 1933-03-30 1934-07-10 Chester R Pieper Heating device
US2056581A (en) * 1934-12-18 1936-10-06 Mortensen Cornelius Heat exchange apparatus
US2687876A (en) * 1951-10-17 1954-08-31 Separator Ab Plate type heat exchanger
US3862661A (en) * 1970-01-16 1975-01-28 Leonid Maximovich Kovalenko Corrugated plate for heat exchanger and heat exchanger with said corrugated plate
US4176713A (en) * 1976-02-12 1979-12-04 Helmut Fisher Plate-type heat exchanger
US5036906A (en) * 1986-12-17 1991-08-06 Rylewski Eugeniusz Independent unit for heat exchange between a primary fluid and a secondary fluid, particularly air for ventilation and air conditioning of a room
US5069276A (en) * 1990-02-08 1991-12-03 Oran Heating Equipment Limited Heat exchanger assembly and panel therefor
US6131649A (en) * 1997-09-19 2000-10-17 Millipore Corporation Heat exchange apparatus
US6378603B1 (en) * 1997-07-17 2002-04-30 Denso Corporation Heat exchanger constructed by plural heat conductive plates
US20030047303A1 (en) * 2000-03-07 2003-03-13 Jarl Andersson Heat transfer plate and plate pack for use in a plate heat exchanger
US20090044933A1 (en) * 2007-08-15 2009-02-19 Rolls-Royce Plc Heat exchanger

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8910966D0 (en) * 1989-05-12 1989-06-28 Du Pont Canada Panel heat exchangers formed from thermoplastic polymers
US6719779B2 (en) * 2000-11-07 2004-04-13 Innercool Therapies, Inc. Circulation set for temperature-controlled catheter and method of using the same
US7563248B2 (en) * 2005-03-17 2009-07-21 Smisson-Cartledge Biomedical Llc Infusion fluid heat exchanger and cartridge
SE530574C2 (sv) * 2006-11-20 2008-07-08 Alfa Laval Corp Ab Plattvärmeväxlare
GB2451113A (en) * 2007-07-19 2009-01-21 Rolls Royce Plc Corrugations of a heat exchanger matrix having first and second different amplitudes

Patent Citations (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US441781A (en) * 1890-12-02 teeisen
US1966133A (en) * 1933-03-30 1934-07-10 Chester R Pieper Heating device
US2056581A (en) * 1934-12-18 1936-10-06 Mortensen Cornelius Heat exchange apparatus
US2687876A (en) * 1951-10-17 1954-08-31 Separator Ab Plate type heat exchanger
US3862661A (en) * 1970-01-16 1975-01-28 Leonid Maximovich Kovalenko Corrugated plate for heat exchanger and heat exchanger with said corrugated plate
US4176713A (en) * 1976-02-12 1979-12-04 Helmut Fisher Plate-type heat exchanger
US5036906A (en) * 1986-12-17 1991-08-06 Rylewski Eugeniusz Independent unit for heat exchange between a primary fluid and a secondary fluid, particularly air for ventilation and air conditioning of a room
US5069276A (en) * 1990-02-08 1991-12-03 Oran Heating Equipment Limited Heat exchanger assembly and panel therefor
US6378603B1 (en) * 1997-07-17 2002-04-30 Denso Corporation Heat exchanger constructed by plural heat conductive plates
US6131649A (en) * 1997-09-19 2000-10-17 Millipore Corporation Heat exchange apparatus
US20030047303A1 (en) * 2000-03-07 2003-03-13 Jarl Andersson Heat transfer plate and plate pack for use in a plate heat exchanger
US20090044933A1 (en) * 2007-08-15 2009-02-19 Rolls-Royce Plc Heat exchanger

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20150083380A1 (en) * 2013-09-25 2015-03-26 Giuseppe BETTI Heat exchanger element of large surface
JP2016539305A (ja) * 2013-12-05 2016-12-15 スウェップ インターナショナル アクティエボラーグ 種々のピッチを有する熱交換プレート
JP2016020776A (ja) * 2014-07-15 2016-02-04 国立大学法人 東京大学 熱交換器
US20220128313A1 (en) * 2018-05-29 2022-04-28 Cooler Master Co., Ltd. Heat dissipation plate and method for manufacturing the same
US11680752B2 (en) * 2018-05-29 2023-06-20 Cooler Master Co., Ltd. Heat dissipation plate and method for manufacturing the same
US20210270545A1 (en) * 2018-06-27 2021-09-02 Welcon Inc. Heat transport device and method for manufacturing same
US11959709B2 (en) * 2018-06-27 2024-04-16 Welcon Inc. Heat transport device and method for manufacturing same
USD908101S1 (en) * 2018-11-26 2021-01-19 Ptt Global Chemical Public Company Limited Microchannel heat exchanger
USD908100S1 (en) * 2018-11-26 2021-01-19 Ptt Global Chemical Public Company Limited Microchannel heat exchanger
USD908644S1 (en) * 2018-11-26 2021-01-26 Ptt Global Chemical Public Company Limited Microchannel heat exchanger

Also Published As

Publication number Publication date
EP2461854A1 (de) 2012-06-13
ES2423057T3 (es) 2013-09-17
EP2461854B1 (de) 2013-05-01
IT1399277B1 (it) 2013-04-11
WO2011015961A1 (en) 2011-02-10
ITTV20090156A1 (it) 2011-02-04

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