US20100003297A1 - Implantable Drug Delivery Device and Methods of Treating Male Genitourinary and Surrounding Tissues - Google Patents

Implantable Drug Delivery Device and Methods of Treating Male Genitourinary and Surrounding Tissues Download PDF

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Publication number
US20100003297A1
US20100003297A1 US12/538,580 US53858009A US2010003297A1 US 20100003297 A1 US20100003297 A1 US 20100003297A1 US 53858009 A US53858009 A US 53858009A US 2010003297 A1 US2010003297 A1 US 2010003297A1
Authority
US
United States
Prior art keywords
drug
device body
release
payload
drug delivery
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
US12/538,580
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English (en)
Inventor
Irene Sophie Tobias
Heejin Lee
Michael J. Cima
Jordan Dimitrakov
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Childrens Medical Center Corp
Massachusetts Institute of Technology
Original Assignee
Childrens Medical Center Corp
Massachusetts Institute of Technology
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US11/463,956 external-priority patent/US8801694B2/en
Application filed by Childrens Medical Center Corp, Massachusetts Institute of Technology filed Critical Childrens Medical Center Corp
Priority to US12/538,580 priority Critical patent/US20100003297A1/en
Assigned to MASSACHUSETTS INSTITUTE OF TECHNOLOGY reassignment MASSACHUSETTS INSTITUTE OF TECHNOLOGY ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: CIMA, MICHAEL J., TOBIAS, IRENE SOPHIE, LEE, HEEJIN
Assigned to CHILDREN'S MEDICAL CENTER CORPORATION reassignment CHILDREN'S MEDICAL CENTER CORPORATION ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: DIMITRAKOV, JORDAN
Publication of US20100003297A1 publication Critical patent/US20100003297A1/en
Priority to US13/910,730 priority patent/US10532132B2/en
Abandoned legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0004—Osmotic delivery systems; Sustained release driven by osmosis, thermal energy or gas
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L29/00—Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
    • A61L29/04—Macromolecular materials
    • A61L29/06—Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L29/00—Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
    • A61L29/14—Materials characterised by their function or physical properties, e.g. lubricating compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L29/00—Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
    • A61L29/14—Materials characterised by their function or physical properties, e.g. lubricating compositions
    • A61L29/16—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/04—Macromolecular materials
    • A61L31/06—Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/16—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M31/00—Devices for introducing or retaining media, e.g. remedies, in cavities of the body
    • A61M31/002—Devices for releasing a drug at a continuous and controlled rate for a prolonged period of time
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L67/00—Compositions of polyesters obtained by reactions forming a carboxylic ester link in the main chain; Compositions of derivatives of such polymers
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L83/00—Compositions of macromolecular compounds obtained by reactions forming in the main chain of the macromolecule a linkage containing silicon with or without sulfur, nitrogen, oxygen or carbon only; Compositions of derivatives of such polymers
    • C08L83/04—Polysiloxanes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
    • A61L2300/21—Acids

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Vascular Medicine (AREA)
  • Surgery (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Anesthesiology (AREA)
  • Hematology (AREA)
  • Reproductive Health (AREA)
  • Gynecology & Obstetrics (AREA)
  • Polymers & Plastics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Materials For Medical Uses (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
  • Medicinal Preparation (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
US12/538,580 2005-08-11 2009-08-10 Implantable Drug Delivery Device and Methods of Treating Male Genitourinary and Surrounding Tissues Abandoned US20100003297A1 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
US12/538,580 US20100003297A1 (en) 2005-08-11 2009-08-10 Implantable Drug Delivery Device and Methods of Treating Male Genitourinary and Surrounding Tissues
US13/910,730 US10532132B2 (en) 2005-08-11 2013-06-05 Implantable drug delivery device and methods

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US70767605P 2005-08-11 2005-08-11
US72649005P 2005-10-12 2005-10-12
US11/463,956 US8801694B2 (en) 2005-08-11 2006-08-11 Intravesical drug delivery device
US8768708P 2008-08-09 2008-08-09
US12/538,580 US20100003297A1 (en) 2005-08-11 2009-08-10 Implantable Drug Delivery Device and Methods of Treating Male Genitourinary and Surrounding Tissues

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
US11/463,956 Continuation-In-Part US8801694B2 (en) 2005-08-11 2006-08-11 Intravesical drug delivery device

Related Child Applications (1)

Application Number Title Priority Date Filing Date
US13/910,730 Division US10532132B2 (en) 2005-08-11 2013-06-05 Implantable drug delivery device and methods

Publications (1)

Publication Number Publication Date
US20100003297A1 true US20100003297A1 (en) 2010-01-07

Family

ID=41151802

Family Applications (2)

Application Number Title Priority Date Filing Date
US12/538,580 Abandoned US20100003297A1 (en) 2005-08-11 2009-08-10 Implantable Drug Delivery Device and Methods of Treating Male Genitourinary and Surrounding Tissues
US13/910,730 Active 2030-07-24 US10532132B2 (en) 2005-08-11 2013-06-05 Implantable drug delivery device and methods

Family Applications After (1)

Application Number Title Priority Date Filing Date
US13/910,730 Active 2030-07-24 US10532132B2 (en) 2005-08-11 2013-06-05 Implantable drug delivery device and methods

Country Status (10)

Country Link
US (2) US20100003297A1 (de)
EP (1) EP2328628A2 (de)
JP (1) JP5908279B2 (de)
KR (2) KR101794899B1 (de)
CN (1) CN102176931B (de)
BR (1) BRPI0917135A2 (de)
CA (1) CA2733468C (de)
EA (1) EA201170297A1 (de)
HK (1) HK1158992A1 (de)
WO (1) WO2010019507A2 (de)

Cited By (38)

* Cited by examiner, † Cited by third party
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US20070202151A1 (en) * 2005-08-11 2007-08-30 Massachusetts Institute Of Technology Intravesical drug delivery device and method
US20090149833A1 (en) * 2007-12-11 2009-06-11 Massachusetts Institute Of Technology Implantable Drug Delivery Device and Methods for Treatment of the Bladder and Other Body Vesicles or Lumens
US20100331770A1 (en) * 2009-06-26 2010-12-30 Taris Biomedical, Inc. Implantable Drug Delivery Devices and Methods of Making the Same
US20110052497A1 (en) * 2009-08-27 2011-03-03 Taris Biomedical, Inc. Minimally Invasive Systems and Methods for In Vivo Testing of Materials
US20110060309A1 (en) * 2009-09-10 2011-03-10 Taris Biomedical, Inc. Implantable Device for Controlled Drug Delivery
US20110137244A1 (en) * 2009-12-08 2011-06-09 Taris Biomedical, Inc. Tissue Expander Configured for Drug Delivery
US20110152839A1 (en) * 2009-12-17 2011-06-23 Taris Biomedical, Inc. Implantable Device with Intravesical Tolerability and Methods of Treatment
US20110202036A1 (en) * 2009-09-10 2011-08-18 Taris Biomedical, Inc. Systems and Methods for Deploying Devices to Genitourinary Sites
WO2012047931A1 (en) * 2010-10-04 2012-04-12 Massachusetts Institute Of Technology Device for local drug delivery and treatment of cerebral edema and other brain-related diseases
WO2012106714A1 (en) 2011-02-04 2012-08-09 Taris Biomedical, Inc. Implantable device for controlled release of low solubility drug
WO2014047221A1 (en) 2012-09-18 2014-03-27 Taris Biomedical, Inc. Drug delivery systems and methods for treatment of bladder voiding dysfunction|and other lower urinary tract disorders by using trospium
US8690840B2 (en) 2010-10-06 2014-04-08 Taris Biomedical, Inc. Time-selective bioresorbable or collapsible drug delivery systems and methods
WO2014138214A1 (en) 2013-03-05 2014-09-12 Taris Biomedical, Inc. Drug delivery devices and methods for controlled drug release through device orifice
WO2014144066A1 (en) 2013-03-15 2014-09-18 Taris Biomedical, Inc Drug delivery devices and methods for drug delivery
WO2015069723A1 (en) * 2013-11-05 2015-05-14 Taris Biomedical Llc Osmotic drug delivery devices, kits, and methods
US9114111B2 (en) 2011-01-10 2015-08-25 Allergan, Inc. Methods for sustained treatment of bladder pain and irritative voiding
WO2015134911A1 (en) 2014-03-06 2015-09-11 Taris Biomedical Llc Drug delivery systems and methods for treatment of bladder cancer with gemcitabine
US9283361B2 (en) 2010-08-05 2016-03-15 Taris Biomedical Llc Implantable drug delivery devices for genitourinary sites
US9457176B2 (en) 2010-10-06 2016-10-04 Taris Biomedical Llc Implantable drug delivery device with bladder retention feature
WO2016160934A1 (en) 2015-03-30 2016-10-06 Taris Biomedical Llc Devices and methods for local delivery of drug to upper urinary tract
WO2017083753A1 (en) * 2015-11-12 2017-05-18 Herr John C Compositions and methods for vas-occlusive contraception and reversal thereof
US10058688B2 (en) 2012-05-09 2018-08-28 Massachusetts Institute Of Technology Medicament, method, and drug delivery device for treatment of ovarian cancer
US10286199B2 (en) 2013-03-15 2019-05-14 Taris Biomedical Llc Drug delivery devices with drug-permeable component and methods
US10406335B2 (en) 2012-08-31 2019-09-10 Taris Biomedical Llc Drug delivery systems and methods for treatment of prostate
US10420818B2 (en) 2014-05-08 2019-09-24 Wake Forest University Health Sciences Methods of treating incontinence and other sphincter deficiency disorders
US10729823B2 (en) 2013-08-19 2020-08-04 Taris Biomedical Llc Multi-unit drug delivery devices and methods
US10751124B2 (en) 2017-01-05 2020-08-25 Contraline, Inc. Methods for implanting and reversing stimuli-responsive implants
US10894150B2 (en) 2015-04-23 2021-01-19 Taris Biomedical Llc Drug delivery devices with drug-permeable component and methods
US10912933B2 (en) 2014-08-19 2021-02-09 The Regents Of The University Of California Implants for localized drug delivery and methods of use thereof
USD918388S1 (en) 2018-06-15 2021-05-04 Wiesman Holdings, LLC Solution diffusing head
US11020575B2 (en) 2017-02-01 2021-06-01 Taris Biomedical Llc In vivo drug delivery devices and methods for drug delivery
US11173291B2 (en) 2020-03-20 2021-11-16 The Regents Of The University Of California Implantable drug delivery devices for localized drug delivery
US11207509B2 (en) 2017-06-15 2021-12-28 Wiesman Holdings, LLC Method and device for delivery of a solution into a body orifice
US11253391B2 (en) 2018-11-13 2022-02-22 Contraline, Inc. Systems and methods for delivering biomaterials
US11338119B2 (en) 2020-03-20 2022-05-24 The Regents Of The University Of California Implantable drug delivery devices for localized drug delivery
US11344526B2 (en) 2020-03-20 2022-05-31 The Regents Of The University Of California Implantable drug delivery devices for localized drug delivery
US11446322B2 (en) 2017-07-25 2022-09-20 Taris Biomedical Llc Methods of treating tumor metastasis
US11654181B2 (en) 2017-08-11 2023-05-23 Wake Forest University Health Sciences Use of CXCL12 for therapy after prostate surgery

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US7702378B2 (en) 2005-11-17 2010-04-20 Breast-Med, Inc. Tissue marker for multimodality radiographic imaging
US11241296B2 (en) 2005-11-17 2022-02-08 Breast-Med, Inc. Imaging fiducial markers and methods
FR2954135B1 (fr) * 2009-12-23 2012-02-24 Oreal Composition cosmetique comprenant au moins un compose organique du silicium, au moins un tensioactif anionique et au moins une silicone aminee ainsi qu'un procede mettant en oeuvre ladite composition
MX370368B (es) 2012-05-19 2019-12-11 Taris Biomedical Llc Dispositivo urologico implantable con caracteristica de extraccion mejorada.
RU2657591C2 (ru) 2012-08-31 2018-06-14 ТАРИС Биомедикал ЛЛК Способ лечения рака мочевого пузыря оксалиплатином, соответствующее устройство его доставки, способ и устройство его введения
ES2940478T3 (es) 2014-06-26 2023-05-08 Taris Biomedical Llc Dispositivos de administración de fármacos intravesicales y métodos que incluyen sistemas de matriz de polímero-fármaco elásticos
US9795455B2 (en) 2014-08-22 2017-10-24 Breast-Med, Inc. Tissue marker for multimodality radiographic imaging
KR20160028762A (ko) 2014-09-04 2016-03-14 강원대학교산학협력단 층간변위구속을 통한 건축물의 진동제어시스템
KR20210039403A (ko) 2018-08-01 2021-04-09 타리스 바이오메디컬 엘엘씨 트로스피움을 사용한 과민성 방광의 치료 방법
CN117136086A (zh) * 2021-04-20 2023-11-28 科利耳有限公司 身体腔室治疗物质递送

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JP5908279B2 (ja) 2016-04-26
EP2328628A2 (de) 2011-06-08
KR101689786B1 (ko) 2016-12-26
WO2010019507A2 (en) 2010-02-18
WO2010019507A3 (en) 2011-02-24
US10532132B2 (en) 2020-01-14
KR101794899B1 (ko) 2017-11-07
CA2733468A1 (en) 2010-02-18
BRPI0917135A2 (pt) 2015-11-10
JP2011530390A (ja) 2011-12-22
HK1158992A1 (en) 2012-07-27
EA201170297A1 (ru) 2011-08-30
KR20160104097A (ko) 2016-09-02
US20130324946A1 (en) 2013-12-05
CN102176931B (zh) 2015-03-04
CN102176931A (zh) 2011-09-07
CA2733468C (en) 2017-12-05
KR20110042352A (ko) 2011-04-26

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