US20070066972A1 - Ablation catheter apparatus with one or more electrodes - Google Patents

Ablation catheter apparatus with one or more electrodes Download PDF

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Publication number
US20070066972A1
US20070066972A1 US11/551,162 US55116206A US2007066972A1 US 20070066972 A1 US20070066972 A1 US 20070066972A1 US 55116206 A US55116206 A US 55116206A US 2007066972 A1 US2007066972 A1 US 2007066972A1
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United States
Prior art keywords
catheter
electrode
distal end
end portion
antenna
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
US11/551,162
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English (en)
Inventor
Theodore Ormsby
George Leung
Gwo Shen
Peter Chu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
MedWaves Inc
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MedWaves Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US10/306,757 external-priority patent/US7004938B2/en
Application filed by MedWaves Inc filed Critical MedWaves Inc
Priority to US11/551,162 priority Critical patent/US20070066972A1/en
Assigned to MEDWAVES, INC. reassignment MEDWAVES, INC. ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: CHU, PETER, LEUNG, GEORGE L., ORMSBY, THEODORE C., SHEN, GWO JENN
Publication of US20070066972A1 publication Critical patent/US20070066972A1/en
Priority to US11/781,467 priority patent/US8308722B2/en
Priority to EP07853876.6A priority patent/EP2073738B1/en
Priority to CN2007800389107A priority patent/CN101534737B/zh
Priority to ES07853876.6T priority patent/ES2546754T3/es
Priority to PCT/US2007/080819 priority patent/WO2008051708A2/en
Assigned to JOHNSON & JOHNSON DEVELOPMENT CORPORATION reassignment JOHNSON & JOHNSON DEVELOPMENT CORPORATION SECURITY INTEREST/LICENSE Assignors: MEDWAVES, INC.
Assigned to MEDWAVES, INC. reassignment MEDWAVES, INC. TERMINATION OF LICENSE Assignors: JOHNSON & JOHNSON DEVELOPMENT CORPORATION
Abandoned legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • A61B18/14—Probes or electrodes therefor
    • A61B18/1492—Probes or electrodes therefor having a flexible, catheter-like structure, e.g. for heart ablation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/00234—Surgical instruments, devices or methods, e.g. tourniquets for minimally invasive surgery
    • A61B2017/00292—Surgical instruments, devices or methods, e.g. tourniquets for minimally invasive surgery mounted on or guided by flexible, e.g. catheter-like, means
    • A61B2017/003—Steerable
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00636—Sensing and controlling the application of energy
    • A61B2018/00773—Sensed parameters
    • A61B2018/00839—Bioelectrical parameters, e.g. ECG, EEG
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/0091—Handpieces of the surgical instrument or device
    • A61B2018/00916—Handpieces of the surgical instrument or device with means for switching or controlling the main function of the instrument or device
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/0091—Handpieces of the surgical instrument or device
    • A61B2018/00916—Handpieces of the surgical instrument or device with means for switching or controlling the main function of the instrument or device
    • A61B2018/0094—Types of switches or controllers
    • A61B2018/00946—Types of switches or controllers slidable
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/18—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves
    • A61B18/1815—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using microwaves
    • A61B2018/183—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using microwaves characterised by the type of antenna

Definitions

  • the present invention generally relates to medical devices used for ablation of biological tissues, and more particularly to an ablation catheter apparatus incorporating one or more electrodes such as electrocardiogram (ECG) electrodes.
  • ECG electrocardiogram
  • Ablation catheters apply energy to a biological tissue site which requires ablation. Such catheters may use various energy modes, such as radiofrequency, ultrasound, laser, cryogenic, and the like.
  • Radio frequency (“RF”) ablation catheters generally operate in the microwave frequency range and are used to destroy or ablate biological tissues for therapeutic purposes.
  • microwave ablation catheters are used to ablate cardiac tissues that cause irregular heartbeats or arrhythmia, avoiding the need for more risky and invasive open heart surgery.
  • the catheter-antenna is passed through the vein for access to the atrium. Within the atrium, the antenna is positioned at the desired location where ablation is required.
  • An intracardiac electrogram is used to identify conductive pathways at the cardiac tissue site that needs to be ablated.
  • Prior art ablation catheters have been equipped with two or more electrocardiogram (“ECG”) electrode rings or buttons made of electrically conductive material to provide the necessary output signal for identification of the desired ablation site.
  • ECG electrocardiogram
  • all catheters used for this purpose are installed with metallic electrodes, regardless of energy mode (RF, ultrasound, laser, cryogenic, or the like).
  • Installing metallic electrodes over a microwave antenna has special challenges. Naked metallic electrodes installed wrongly can absorb ablation energy and become hot. Hot electrodes can have adverse effects on the heart or other biological tissues or organs, such as blood clot formation, adherence to tissue, and tissue charring. Naked metallic electrodes can also impede efficient delivery of energy and hinder ablation efficiency. Additionally, metallic electrodes can separate from the catheter when it is bent, resulting in inaccurate or lost signals.
  • the ablation catheter system of this invention comprises an elongate catheter adapted for insertion into a body vessel of a patient, the catheter having a distal end portion adapted for positioning adjacent a biological tissue site requiring treatment and a proximal end portion having a connector for connection to a control unit for controlling the ablation procedure, an antenna disposed at the distal end portion of the catheter for providing output energy for tissue ablation purposes, a pair of conductors extending through the catheter from the proximal end portion and connected to the antenna for providing power to the antenna from a power supply in the control unit, and at least one electrode formed of a flexible conductive material disposed at the distal end portion of the antenna and connected to the connector at the proximal end portion of the catheter for providing an output signal to the control unit.
  • the flexible conductive material is at least substantially non-metallic.
  • Electrodes may be disposed at the distal end portion of the catheter.
  • the electrode or electrodes are of conductive polymer material with hydrophilic characteristics for improved wetability.
  • Two spaced electrode rings are mounted on or embedded in the outer surface of the cathode.
  • one electrode ring may be provided and the other electrode may be a tip of conductive polymer material at the distal end of the catheter.
  • layers of conductive and nonconductive polymer material may be provided at specific positions at the distal end portion of the catheter to produce multiple working electrodes.
  • the electrode output signal can be connected to a suitable electrode recording system inputs in the control unit or a separate electrocardiogram unit to provide intracardiac signal mapping.
  • This arrangement avoids the problems of metallic electrodes and also provides electrodes which are of a flexible polymer material which can bend readily with the distal end portion of the catheter as it is shaped or bent to negotiate a path through a body vessel.
  • FIGS. 1A and 1B are side elevation views of a shapeable RF ablation catheter according to one embodiment in a straight and bent configuration, respectively;
  • FIGS. 2A and 2B are side elevation views of a shapeable RF ablation catheter according to another embodiment with a different steering mechanism from FIG. 1 ;
  • FIGS. 3A and 3B are cross sectional views of the distal end portion of the tip of the catheter of FIG. 1 or 2 in a straight configuration and a bent configuration, respectively;
  • FIG. 4 is a cross-sectional view of the tip or distal end portion of one embodiment of a shapeable or bendable RF ablation catheter incorporating electrodes;
  • FIG. 5 is a cross-sectional view of the tip or distal end portion of a shapeable or bendable RF ablation catheter having a modified electrode arrangement according to another embodiment
  • FIG. 6 is a cross-sectional view of the tip or distal end portion of a shapeable or bendable RF ablation catheter with another electrode arrangement
  • FIG. 7 is a cross-sectional view of the tip or distal end portion of a shapeable or bendable RF ablation catheter with a modified electrode arrangement according to another embodiment.
  • FIG. 8 is a cross-sectional view of the tip or distal end portion of a shapeable or bendable RF ablation catheter with modified electrodes according to another embodiment.
  • Certain embodiments as disclosed herein provide for systems and methods for ablation of biological tissues in body areas such as the heart, liver, and the like using a bendable radio-frequency (RF) catheter.
  • the catheter is provided with electrodes of a flexible conductive material such as a conductive polymer at its distal end for providing an output signal such as an intracardiac electrocardiogram (“ECG”) signal to a control unit to allow physicians to obtain tissue proximity and electrical conductivity information both before and after tissue ablation, as well as to provide other feedback during the ablation procedure.
  • ECG intracardiac electrocardiogram
  • FIGS. 1A and 1B illustrate a radio-frequency (“RF”) ablation catheter system 100 of one embodiment including a shapeable catheter device 100 adapted for insertion into a body vessel of a patient and incorporating an RF antenna for delivering electromagnetic energy to a treatment site, as described in more detail below.
  • RF radio-frequency
  • the catheter device 100 has a flexible, elongated tubular body 120 having a proximal portion 130 and a distal or tip portion 140 .
  • a handle chassis 160 Located at the proximal portion of the body is a handle chassis 160 containing steering and positioning controls (not illustrated) for the body, activated by actuator 200 .
  • the tip portion of the catheter body is activated to bend between the straight configuration of FIG. 1A and the bent configuration of FIG. 1B by sliding the actuator back and forth in an axial direction.
  • the tip portion is bent between the straight and bent configurations by rotating the actuator or collar 220 .
  • Suitable mechanisms for controlling bending of the tip portion of catheter body 120 are described in detail in U.S. Pat. No. 7,004,938 of Ormsby et al., the contents of which are incorporated herein by reference. However, it will be understood that any suitable mechanism may be incorporated in the catheter device in order to control the bending or steering of the tip portion as it moves through a body vessel, organ, or cavity.
  • a coupling or electrical connector 170 is provided at the proximal end of the catheter device for connecting the catheter to a control unit or the like containing one or more electronic devices such as an RF generator and controller (not shown) for providing power to the antenna during an ablation procedure.
  • a control unit or the like containing one or more electronic devices such as an RF generator and controller (not shown) for providing power to the antenna during an ablation procedure.
  • Suitable signal control units are known in the ablation catheter field and are therefore not described in detail here.
  • the dimensions of the catheter body are adapted as required to suit the particular medical procedure, as is well known in the medical art.
  • the catheter is used to ablate cardiac tissue.
  • the catheter may be used to ablate other types of body tissue in different organs, both internal and external to the body.
  • the tubular body 120 of the catheter device may be generally constructed of a polymer material which is bio-compatible with the body vessel environment. Examples of such materials include thermoplastic elastomer material such as Pebaxg available from Autochem Germany, polyethylene, polyurethane, polyester, polyimide, polyamide, and the like, with varying degrees of radiopacity, hardness, and elasticity.
  • the tubular body of the catheter may be formed with a plurality of segments using one or more of the aforementioned materials or equivalents, such that the catheter body 120 is progressively more flexible towards its distal end.
  • the segments may be joined together by thermal bonding, butt joints, or adhesive bonding.
  • Braiding reinforcement may be provided to the surface of the tubular body to attain a desirable level of stiffness and torsional strength for the catheter to advance and negotiate through the body vessel of the patient, while still allowing the distal end portion to be bent when needed.
  • the distal end portion 140 may be of a softer polymer compound than the remainder of the body, with little or no braiding or reinforcement, to provide the desired flexibility for distal deflection and shaping of the apparatus.
  • the catheter has a tubular body with a central bore 150 and a closed distal end or tip.
  • the tip may be open in alternative embodiments.
  • deflection of the distal end portion of the catheter is accomplished by use of a pre-shaped deflection member 180 which is constrained in a straight orientation in the configuration of FIG. 3A and which adopts a bent shape when extended into the bent configuration of FIG. 3B .
  • a pre-shaped deflection member 180 which is constrained in a straight orientation in the configuration of FIG. 3A and which adopts a bent shape when extended into the bent configuration of FIG. 3B .
  • other bending or shaping mechanisms may be used in alternative embodiments, as described, for example, in U.S. Pat. No. 7,004,938 referenced above.
  • the distal end portion 140 of the tubular body includes an RF antenna 250 comprising a flexible, helically coiled radiating antenna device 255 embedded in the flexible wall of the tubular body, as best illustrated in FIGS. 3A and 3B .
  • the antenna device can therefore bend as the distal end portion is shaped to conform to a body vessel or the like, as illustrated in FIG. 3B .
  • Opposite ends of the antenna device are connected to electrical conductors or leads for connection to the proximal end connector 170 and thereby to a source of RF energy in the catheter control unit (not illustrated), as will be described in more detail below in connection with FIG. 4 .
  • Other antenna devices may be provided in alternative embodiments, and the diameter, pitch and length of the coiled device 255 , and the conductive material used for the device 255 , may vary according to the particular procedure and flexibility requirements.
  • the electrical conductors which connect the RF antenna to the connector 170 may be of a flexible mesh or braided wire construction 260 or of a thin-film electrically conductive material.
  • the conductors are shown schematically as a mesh construction embedded in the walls of the tubular body 120 of the catheter. In alternative arrangements, separate conductors may be used to provide power to the antenna 250 .
  • FIG. 4 illustrates the distal end portion 310 of a first embodiment of a modified catheter having integrated electrodes 312 , 314 .
  • the electrodes are ECG electrodes, although they may be other types of electrodes in other embodiments. Although two electrodes are illustrated in FIG.
  • a pair of coaxial inner and outer tubular conductors 315 , 316 extend along the length of the tubular body 318 , with the outer conductor 316 connected to the proximal end of RF antenna 250 and the inner conductor 315 connected to the distal end of the RF antenna adjacent the tip of the catheter.
  • the structure of the remainder of the tubular body 318 which is not shown in FIG.
  • FIG. 4 may be identical to that of tubular body 120 described above, and a similar connector 170 (not illustrated) may be provided at the proximal end of the catheter for connecting the conductors to a suitable RF source.
  • the distal end portion illustrated in FIG. 4 will be shapeable or bendable in a similar manner and using the same or similar control devices as were described above in connection with FIGS. 1 to 3 .
  • the tubular body 318 is of dielectric material such as a non-conductive polymer and has a portion 320 of reduced outer diameter at its forward end.
  • the first electrode 312 comprises a sleeve of flexible conductive material mounted over the reduced diameter end portion 320 of the tubular body and having an end portion or tip 322 extending over the open end of portion 320 .
  • the RF or microwave antenna 250 is embedded in the sleeve or electrode 312 .
  • the inner and outer conductors 315 , 316 extend through the tubular body 318 as illustrated for connection to the opposite ends of the antenna coil 250 .
  • the second electrode 314 comprises a ring of flexible conductive material mounted over the tubular body 318 at a location spaced rearwardly from the rear end of conductive sleeve or electrode 312 .
  • the two electrodes may be secured over the inner tubular body 318 by adhesive, bonding, mechanical force, heat sealing or the like.
  • the flexible conductive material forming the electrodes is at least substantially non-metallic material and may be a conductive polymer material which is sufficiently bendable to allow bending of the distal end portion 310 between the positions illustrated in FIGS. 1A and 1B .
  • the electrode ring 314 may be mounted flush in an annular recess or gap in the outer surface of the tubular body, or may be molded integrally with the tubular body, so that it does not project outwardly from the outer surface of the body 318 .
  • a conductor or connector 324 extends from electrode ring 314 to the connector 170 at the proximal end of the catheter, for suitable connection to an ECG monitor or the like in a control unit (not illustrated) for the catheter.
  • Conductor 324 is shown spaced from the outer surface of body 318 in FIG.
  • both electrodes are of a flexible, conductive polymer material, i.e. a polymer material loaded with conductive materials.
  • FIG. 5 illustrates the distal end portion 325 of a catheter with a modified electrode arrangement in which the electrode ring 314 of FIG. 4 is replaced by an electrode end cap 330 .
  • Electrodes 312 , 330 are of flexible conductive material such as a conductive polymer material as in FIG. 4 .
  • the conductive sleeve 312 in which the antenna is mounted has an outer cover layer 332 of non-conductive polymer material extending along at least part of its length and over its distal end, providing a non-conductive shield layer between the first and second electrodes 312 , 330 .
  • a conductor or connector wire 334 extends from the connector at the proximal end of the catheter through the central lumen 150 of the tubular body 318 and into the electrode end cap 330 to provide a signal path between the electrode and the ECG monitor.
  • the catheter of FIG. 5 is otherwise identical to that of the previous embodiment and like reference numerals have been used as appropriate.
  • Conductive sleeve 312 , non-conductive layer 332 , and end cap 330 may be laminated together over the tubular body 318 by any suitable means such as bonding, heat sealing, adhesive, or the like.
  • FIG. 6 illustrates the distal end portion 340 of a catheter having another modified electrode arrangement.
  • Parts of the cathode of this embodiment are identical to those of FIGS. 4 and 5 and like reference numerals have been used for like parts as appropriate.
  • the sleeve 335 in which the antenna coil 250 is embedded does not comprise one of the two electrodes.
  • sleeve 335 is mounted over the reduced diameter end portion 320 of the tubular body 318 , which is of dielectric or non-conductive material, and the antenna coil 250 is connected at its opposite ends to the distal ends of the inner and outer conductors 315 , 316 .
  • an outer layer 336 of non-conductive material extends over the conductive sleeve 335 and has an end cap portion 338 extending over the tip of the tubular body 318 .
  • the electrodes in this embodiment comprise a pair of conductive rings 339 , 341 mounted at spaced intervals on the outer, non-conductive layer 336 .
  • the ring electrodes may be of conductive polymer material.
  • the first ring 339 is positioned adjacent the non-conductive end cap portion 338 and the second ring 341 is positioned adjacent the rear end of the conductive layer 336 .
  • a central conductor or connector wire 342 extends through the hollow central bore or lumen of the tubular body 318 , through the non-conductive end cap portion 338 , and bends back to terminate in the first conductive ring electrode 339 .
  • the part of connector wire 342 shown extending through lumen 150 may be a line of conductive ink or adhesive on the inner surface of tubular body 318 .
  • a second conductor or connector wire 343 extends along the outside of the tubular body 318 and is connected to the second conductive ring electrode 341 .
  • the connector wire 343 may comprise a line of conductive ink or adhesive on tubular body 318 , or may alternatively be embedded in the tubular body 318 at location spaced outside the outer tubular conductor 316 .
  • the various conductive and non-conductive polymer layers of the distal end portion 340 , including the electrode rings, are suitably laminated together by heat sealing, adhesive bonding, or the like.
  • a pull wire 355 which extends through the lumen 150 to the tip 338 and is attached to suitable steering and positioning controls (not illustrated) at the proximal end of the catheter, for controlling bending of the distal end portion.
  • suitable steering and positioning controls not illustrated
  • Such a pull wire mechanism is described in U.S. Pat. No. 7,004,938 referenced above, the contents of which are incorporated herein by reference. It may be understood that a similar position control mechanism will be provided in the embodiments of FIGS. 4 to 6 , or the mechanism 180 of FIG. 3 may be provided in any of these embodiments.
  • FIG. 7 illustrates the distal end portion 400 of a catheter according to another embodiment. Again, some parts of the catheter illustrated in FIG. 7 are identical to those of FIGS. 4 to 6 and like reference numerals have been used as appropriate.
  • a tubular body 318 of flexible dielectric material extends the length of the catheter and has a central through bore or lumen 150 and an end portion 320 of reduced outer diameter over which the sleeve 312 containing embedded RF antenna 250 is mounted.
  • sleeve 312 is of conductive polymer material and the ends of the antenna are connected to the distal end connector 170 ( FIG.
  • an outer cover layer 345 of non-conductive polymer material extends along the entire length of the catheter, over the tubular body 318 and sleeve 312 , and has a forward end or tip 344 covering the forward end of the sleeve and tubular body.
  • a pair of contact rings 346 , 348 are mounted in the outer cover layer 345 in the distal end portion of the catheter, with the forward contact ring 346 located over the sleeve 312 and in electrical contact with the sleeve, and the rear contact ring 348 located slightly rearwardly from sleeve 312 .
  • Each ring is of a flexible conductive material such as conductive polymer material. Rings 346 , 348 and outer cover layer 345 are suitably bonded together and laminated over the tubular body 318 and conductive polymer sleeve 312 .
  • the forward contact ring 346 is connected to the proximal end connector 170 via the conductive sleeve 312 and the outer conductor 316 which also provides power to the antenna 250 .
  • the rear contact ring 348 is connected to a conductive wire 350 which extends through the tubular body 318 to the proximal end connector 170 of the catheter.
  • the conductors 316 , 350 therefore provide the output for the ECG monitor in the control unit in this embodiment.
  • the embodiment of FIG. 7 also includes a temperature sensor 352 in the lumen 150 adjacent the tip of the catheter.
  • the temperature sensor 352 may be a thermistor, thermocouple, or the like and has a thermocouple junction or sensor end 352 and a pair of braided wires or conductors 354 extending from the sensor 352 through the tubular body to the connector 170 at the proximal end of the catheter, where they are connected to control circuitry for monitoring the temperature at the distal end of the catheter and controlling the antenna operation.
  • a pull wire 355 is attached to the tip 344 of the catheter and extends through the central lumen 150 through the length of the catheter for attachment to a suitable steering and control mechanism (not illustrated), as in the previous embodiment.
  • FIG. 8 illustrates a modification of the embodiment of FIG. 5 , and like reference numerals are used for like parts as appropriate.
  • a tubular body 318 of dielectric material having a central lumen 150 extends the entire length of the catheter, and has a reduced outer diameter portion 320 at the distal end portion 500 of the catheter.
  • Conductive sleeve 312 is mounted over the portion 320 and the RF antenna 250 is embedded in sleeve 312 .
  • the electrodes comprise the conductive sleeve 312 and a conductive tip 330 mounted over the end of the catheter, with a layer 332 of non-conductive material such as non-conductive polymer between the electrodes 312 and 330 .
  • the various layers of conductive and non-conductive materials in the embodiment of FIG. 8 will also be laminated together by any suitable means such as heat, adhesives and mechanical force.
  • thermocouple wires 510 which extend through lumen 150 from the proximal end connector 170 of the catheter and into the conductive tip electrode 330 , with a thermocouple junction 512 at the end of the double wires providing a temperature sensor.
  • the thermocouple wires therefore have the dual function of providing a temperature sensor output as well as providing an ECG monitor output in combination with outer antenna conductor 316 .
  • the ECG output may be measured between conductor 316 and either one of the thermocouple wires 510 .
  • the temperature output may be used in monitoring and controlling operation of the RF antenna, as described above in connection with FIG. 7 .
  • electrodes are mounted at the distal end portion of a shapeable or bendable catheter to allow physicians to locate a tissue region causing problems and to obtain both optimum tissue proximity and electrical conductive activities before and after ablation, as well as to obtain feedback of their actions.
  • two electrodes are provided in these embodiments, only one electrode or more than two electrodes may be provided in other embodiments.
  • the electrode or electrodes in these embodiments may be ECG or other types of electrodes.
  • Radio-opaque markers (not illustrated) at the distal end portion of the catheter may also be used to aid in positioning the tip of the catheter, as is known in the field.
  • the conductor wires connected to the electrodes and to the proximal end connector 170 of the catheter will communicate with an external ECG system and monitor (not illustrated) via a suitable connection cable which will transmit ECG signals between the electrodes and ECG system.
  • the antenna conductors and thermocouple wires (if a temperature sensor is present) will be similarly connected to an appropriate antenna output control system.
  • the RF antenna 250 is adapted to receive and radiate electromagnetic energy in order to treat a selected biological tissue site.
  • An example of a suitable spectrum of radio frequency energy for use in the ablation catheter is that of the microwave frequency range above 300 MHz.
  • the RF antenna is capable of applying substantially uniformly distributed electromagnetic field energy along the RF antenna in a direction substantially normal to the longitudinal axis of antenna 250 .
  • the electrodes in the embodiments of FIGS. 4 to 8 are made of a suitable flexible conductive material, so that they can bend with the remainder of the distal end portion during steering. Such electrodes avoid or reduce the problems encountered with metallic electrodes, since they do not absorb microwave energy to any great extent and do not become excessively hot.
  • the electrodes may be of an at least substantially non-metallic material, and in one embodiment they are made from a conductive polymer material such as nylon, polyethylene, polyolefin, polypropylene, polycarbonate, Pebax®, TPE (thermoplastic elastomers) and blends, loaded with a selective conductive material.
  • Other non-conductive parts of the catheter may be of the same polymer material or different polymer materials.
  • the conductive material may be micro-carbon spheres, carbon particles, carbon nanotubes, nickel dust, or the like.
  • the electrodes may be made entirely of conductive polymer material or may be a mixture of conductive and non-conductive polymer material, or a mixture of conductive and non-conductive materials with metal substrates.
  • the composite polymer material is selected to have a relatively low resistance for reduced interference with the microwave radiation pattern, and to be hydrophilic for improved wetability on the outer surface of the catheter.
  • Communication between the electrodes and the connector 170 at the proximal end of the catheter may be provided in some embodiments by means of conductive ink or adhesive applied over the polymer surface.
  • conductor 324 of FIG. 4 or conductor 342 of FIG. 6 may be a line of conductive ink or adhesive over the outer surface of the tubular body 318 extending from electrode ring 314 to the proximal end of the catheter.
  • Conductor 350 of FIG. 7 may be a line of conductive ink or adhesive over the outer surface of non-conductive tubular body 318 , with the outer layer 345 of non-conductive polymer laminated over the tubular body and conductor line 350 .
  • Heat energy, adhesives, and/or mechanical force may be used to laminate the conductive and non-conductive polymer layers in the embodiments of FIGS. 4 to 8 .
  • Metallic substrates may also be laminated between the polymer layers, such as the inner and outer tubular conductors which provide power for operating RF antenna 250 .

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US11/551,162 1998-12-14 2006-10-19 Ablation catheter apparatus with one or more electrodes Abandoned US20070066972A1 (en)

Priority Applications (6)

Application Number Priority Date Filing Date Title
US11/551,162 US20070066972A1 (en) 2001-11-29 2006-10-19 Ablation catheter apparatus with one or more electrodes
US11/781,467 US8308722B2 (en) 1998-12-14 2007-07-23 Hollow conductive coaxial cable for radio frequency based tissue ablation system
PCT/US2007/080819 WO2008051708A2 (en) 2006-10-19 2007-10-09 Ablation catheter apparatus with one or more electrodes
ES07853876.6T ES2546754T3 (es) 2006-10-19 2007-10-09 Aparato de catéter de ablación con uno o más electrodos
CN2007800389107A CN101534737B (zh) 2006-10-19 2007-10-09 具有一个或多个电极的消融导管装置
EP07853876.6A EP2073738B1 (en) 2006-10-19 2007-10-09 Ablation catheter apparatus with one or more electrodes

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US33419901P 2001-11-29 2001-11-29
US10/306,757 US7004938B2 (en) 2001-11-29 2002-11-27 Radio-frequency-based catheter system with improved deflection and steering mechanisms
US11/359,808 US7815637B2 (en) 2001-11-29 2006-02-22 Radio-frequency-based catheter system with improved deflection and steering mechanisms
US11/551,162 US20070066972A1 (en) 2001-11-29 2006-10-19 Ablation catheter apparatus with one or more electrodes

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Cited By (179)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060041277A1 (en) * 2002-04-08 2006-02-23 Mark Deem Methods and apparatus for renal neuromodulation
US20060142752A1 (en) * 2001-11-29 2006-06-29 Ormsby Theodore C Radio-frequency-based catheter system with improved deflection and steering mechanisms
US20060265015A1 (en) * 2002-04-08 2006-11-23 Ardian, Inc. Methods and apparatus for monopolar renal neuromodulation
US20060265014A1 (en) * 2002-04-08 2006-11-23 Ardian, Inc. Methods and apparatus for bilateral renal neuromodulation
US20060276852A1 (en) * 2002-04-08 2006-12-07 Ardian, Inc. Methods and apparatus for treating hypertension
US20070129760A1 (en) * 2002-04-08 2007-06-07 Ardian, Inc. Methods and apparatus for intravasculary-induced neuromodulation or denervation
US20080015570A1 (en) * 1998-12-14 2008-01-17 Ormsby Theodore C Hollow conductive coaxial cable for radio frequency based tissue ablation system
EP2008603A1 (en) * 2007-06-29 2008-12-31 Biosense Webster, Inc. Ablation catheter with optically transparent electricity conductive tip
US20090005771A1 (en) * 2007-06-28 2009-01-01 Chad Allen Lieber Optical Pyrometric Catheter for Tissue Temperature Monitoring During Cardiac Ablation
US20090082762A1 (en) * 2007-09-20 2009-03-26 Ormsby Theodore C Radio frequency energy transmission device for the ablation of biological tissues
US20090163905A1 (en) * 2007-12-21 2009-06-25 Winkler Matthew J Ablation device with internally cooled electrodes
US20090163916A1 (en) * 2007-12-21 2009-06-25 Saurav Paul Flexible Conductive Polymer Electrode and Method for Ablation
US20090171188A1 (en) * 2007-12-28 2009-07-02 Saurav Paul Flexible polymer electrode for mri-guided positioning and radio frequency ablation
US20090171187A1 (en) * 2007-12-26 2009-07-02 Gerhart John P Catheter electrode that can simultaneously emit electrical energy and facilitate visualization by magnetic resonance imaging
US20090299360A1 (en) * 2008-05-28 2009-12-03 Medwaves, Inc. Tissue ablation apparatus and method using ultrasonic imaging
US20100004650A1 (en) * 2008-07-01 2010-01-07 Medwaves, Inc. Angioplasty and tissue ablation apparatus and method
US20100121319A1 (en) * 2008-11-10 2010-05-13 Microcube, Llc Methods and devices for applying energy to bodily tissues
US20100125269A1 (en) * 2008-10-21 2010-05-20 Microcube, Limited Liability Corporation Microwave treatment devices and methods
US20100137857A1 (en) * 2008-10-21 2010-06-03 Microcube, Limited Liability Corporation Methods and devices for applying energy to bodily tissues
US20100168731A1 (en) * 2008-12-31 2010-07-01 Ardian, Inc. Apparatus, systems, and methods for achieving intravascular, thermally-induced renal neuromodulation
US20100168739A1 (en) * 2008-12-31 2010-07-01 Ardian, Inc. Apparatus, systems, and methods for achieving intravascular, thermally-induced renal neuromodulation
US20100268219A1 (en) * 2009-04-15 2010-10-21 Medwaves, Inc. Radio frequency based ablation system and method with dielectric transformer
US20110004205A1 (en) * 2008-10-21 2011-01-06 Chu Chun Yiu Methods and devices for delivering microwave energy
US20110130750A1 (en) * 2009-11-30 2011-06-02 Medwaves, Inc. Radio frequency ablation system with tracking sensor
US20110208096A1 (en) * 2002-04-08 2011-08-25 Ardian, Inc. Methods and apparatus for thermally-induced renal neuromodulation
US8131372B2 (en) 2002-04-08 2012-03-06 Ardian, Inc. Renal nerve stimulation method for treatment of patients
US8150520B2 (en) 2002-04-08 2012-04-03 Ardian, Inc. Methods for catheter-based renal denervation
US8433423B2 (en) 2004-10-05 2013-04-30 Ardian, Inc. Methods for multi-vessel renal neuromodulation
US8454594B2 (en) 2002-04-08 2013-06-04 Medtronic Ardian Luxembourg S.A.R.L. Apparatus for performing a non-continuous circumferential treatment of a body lumen
US20130204279A1 (en) * 2010-05-07 2013-08-08 Carefusion 2200, Inc. Catheter design for use in treating pleural diseases
WO2013119620A1 (en) * 2012-02-07 2013-08-15 Advanced Cardiac Therapeutics, Inc. Systems and methods for radiometrically measuring temperature during tissue ablation
US8548600B2 (en) 2002-04-08 2013-10-01 Medtronic Ardian Luxembourg S.A.R.L. Apparatuses for renal neuromodulation and associated systems and methods
US8620423B2 (en) 2002-04-08 2013-12-31 Medtronic Ardian Luxembourg S.A.R.L. Methods for thermal modulation of nerves contributing to renal function
US20140012077A1 (en) * 2011-01-11 2014-01-09 Quanta System S.P.A. Laser surgery device
US8684998B2 (en) 2002-04-08 2014-04-01 Medtronic Ardian Luxembourg S.A.R.L. Methods for inhibiting renal nerve activity
US8728075B2 (en) 2010-04-26 2014-05-20 Medtronic Ardian Luxembourg S.A.R.L. Multi-directional deflectable catheter apparatuses, systems, and methods for renal neuromodulation
US8774922B2 (en) 2002-04-08 2014-07-08 Medtronic Ardian Luxembourg S.A.R.L. Catheter apparatuses having expandable balloons for renal neuromodulation and associated systems and methods
US8771252B2 (en) 2002-04-08 2014-07-08 Medtronic Ardian Luxembourg S.A.R.L. Methods and devices for renal nerve blocking
US8818514B2 (en) 2002-04-08 2014-08-26 Medtronic Ardian Luxembourg S.A.R.L. Methods for intravascularly-induced neuromodulation
US8880185B2 (en) 2010-06-11 2014-11-04 Boston Scientific Scimed, Inc. Renal denervation and stimulation employing wireless vascular energy transfer arrangement
US8939970B2 (en) 2004-09-10 2015-01-27 Vessix Vascular, Inc. Tuned RF energy and electrical tissue characterization for selective treatment of target tissues
US8951251B2 (en) 2011-11-08 2015-02-10 Boston Scientific Scimed, Inc. Ostial renal nerve ablation
US8954161B2 (en) 2012-06-01 2015-02-10 Advanced Cardiac Therapeutics, Inc. Systems and methods for radiometrically measuring temperature and detecting tissue contact prior to and during tissue ablation
US8958871B2 (en) 2002-04-08 2015-02-17 Medtronic Ardian Luxembourg S.A.R.L. Methods and apparatus for pulsed electric field neuromodulation via an intra-to-extravascular approach
US8961506B2 (en) 2012-03-12 2015-02-24 Advanced Cardiac Therapeutics, Inc. Methods of automatically regulating operation of ablation members based on determined temperatures
US8974445B2 (en) 2009-01-09 2015-03-10 Recor Medical, Inc. Methods and apparatus for treatment of cardiac valve insufficiency
US8974451B2 (en) 2010-10-25 2015-03-10 Boston Scientific Scimed, Inc. Renal nerve ablation using conductive fluid jet and RF energy
WO2015042173A1 (en) * 2013-09-20 2015-03-26 Advanced Cardiac Therapeutics, Inc. Temperature sensing and tissue ablation using a plurality of electrodes
US9023034B2 (en) 2010-11-22 2015-05-05 Boston Scientific Scimed, Inc. Renal ablation electrode with force-activatable conduction apparatus
US9028472B2 (en) 2011-12-23 2015-05-12 Vessix Vascular, Inc. Methods and apparatuses for remodeling tissue of or adjacent to a body passage
US9028485B2 (en) 2010-11-15 2015-05-12 Boston Scientific Scimed, Inc. Self-expanding cooling electrode for renal nerve ablation
US9050106B2 (en) 2011-12-29 2015-06-09 Boston Scientific Scimed, Inc. Off-wall electrode device and methods for nerve modulation
US9060761B2 (en) 2010-11-18 2015-06-23 Boston Scientific Scime, Inc. Catheter-focused magnetic field induced renal nerve ablation
US9079000B2 (en) 2011-10-18 2015-07-14 Boston Scientific Scimed, Inc. Integrated crossing balloon catheter
US9084609B2 (en) 2010-07-30 2015-07-21 Boston Scientific Scime, Inc. Spiral balloon catheter for renal nerve ablation
US9089350B2 (en) 2010-11-16 2015-07-28 Boston Scientific Scimed, Inc. Renal denervation catheter with RF electrode and integral contrast dye injection arrangement
US9119632B2 (en) 2011-11-21 2015-09-01 Boston Scientific Scimed, Inc. Deflectable renal nerve ablation catheter
US9119600B2 (en) 2011-11-15 2015-09-01 Boston Scientific Scimed, Inc. Device and methods for renal nerve modulation monitoring
US9125666B2 (en) 2003-09-12 2015-09-08 Vessix Vascular, Inc. Selectable eccentric remodeling and/or ablation of atherosclerotic material
US9125667B2 (en) 2004-09-10 2015-09-08 Vessix Vascular, Inc. System for inducing desirable temperature effects on body tissue
US9155589B2 (en) 2010-07-30 2015-10-13 Boston Scientific Scimed, Inc. Sequential activation RF electrode set for renal nerve ablation
US9162046B2 (en) 2011-10-18 2015-10-20 Boston Scientific Scimed, Inc. Deflectable medical devices
US9173696B2 (en) 2012-09-17 2015-11-03 Boston Scientific Scimed, Inc. Self-positioning electrode system and method for renal nerve modulation
US9186210B2 (en) 2011-10-10 2015-11-17 Boston Scientific Scimed, Inc. Medical devices including ablation electrodes
US9186209B2 (en) 2011-07-22 2015-11-17 Boston Scientific Scimed, Inc. Nerve modulation system having helical guide
US9192790B2 (en) 2010-04-14 2015-11-24 Boston Scientific Scimed, Inc. Focused ultrasonic renal denervation
US9192435B2 (en) 2010-11-22 2015-11-24 Boston Scientific Scimed, Inc. Renal denervation catheter with cooled RF electrode
US9192715B2 (en) 2002-04-08 2015-11-24 Medtronic Ardian Luxembourg S.A.R.L. Methods for renal nerve blocking
US9220558B2 (en) 2010-10-27 2015-12-29 Boston Scientific Scimed, Inc. RF renal denervation catheter with multiple independent electrodes
US9220561B2 (en) 2011-01-19 2015-12-29 Boston Scientific Scimed, Inc. Guide-compatible large-electrode catheter for renal nerve ablation with reduced arterial injury
US9265969B2 (en) 2011-12-21 2016-02-23 Cardiac Pacemakers, Inc. Methods for modulating cell function
US9277955B2 (en) 2010-04-09 2016-03-08 Vessix Vascular, Inc. Power generating and control apparatus for the treatment of tissue
US9277961B2 (en) 2009-06-12 2016-03-08 Advanced Cardiac Therapeutics, Inc. Systems and methods of radiometrically determining a hot-spot temperature of tissue being treated
US9297845B2 (en) 2013-03-15 2016-03-29 Boston Scientific Scimed, Inc. Medical devices and methods for treatment of hypertension that utilize impedance compensation
US9308044B2 (en) 2002-04-08 2016-04-12 Medtronic Ardian Luxembourg S.A.R.L. Methods for therapeutic renal neuromodulation
US9308043B2 (en) 2002-04-08 2016-04-12 Medtronic Ardian Luxembourg S.A.R.L. Methods for monopolar renal neuromodulation
US9327122B2 (en) 2002-04-08 2016-05-03 Medtronic Ardian Luxembourg S.A.R.L. Methods for catheter-based renal neuromodulation
US9326751B2 (en) 2010-11-17 2016-05-03 Boston Scientific Scimed, Inc. Catheter guidance of external energy for renal denervation
US9327100B2 (en) 2008-11-14 2016-05-03 Vessix Vascular, Inc. Selective drug delivery in a lumen
US9358365B2 (en) 2010-07-30 2016-06-07 Boston Scientific Scimed, Inc. Precision electrode movement control for renal nerve ablation
US9364284B2 (en) 2011-10-12 2016-06-14 Boston Scientific Scimed, Inc. Method of making an off-wall spacer cage
US9408661B2 (en) 2010-07-30 2016-08-09 Patrick A. Haverkost RF electrodes on multiple flexible wires for renal nerve ablation
US9420955B2 (en) 2011-10-11 2016-08-23 Boston Scientific Scimed, Inc. Intravascular temperature monitoring system and method
US9433760B2 (en) 2011-12-28 2016-09-06 Boston Scientific Scimed, Inc. Device and methods for nerve modulation using a novel ablation catheter with polymeric ablative elements
US9439726B2 (en) 2002-04-08 2016-09-13 Medtronic Ardian Luxembourg S.A.R.L. Methods for therapeutic renal neuromodulation
US9463062B2 (en) 2010-07-30 2016-10-11 Boston Scientific Scimed, Inc. Cooled conductive balloon RF catheter for renal nerve ablation
US20160310211A1 (en) * 2014-01-06 2016-10-27 Iowa Approach Inc. Apparatus and methods for renal denervation ablation
US9486355B2 (en) 2005-05-03 2016-11-08 Vessix Vascular, Inc. Selective accumulation of energy with or without knowledge of tissue topography
US9510905B2 (en) 2014-11-19 2016-12-06 Advanced Cardiac Therapeutics, Inc. Systems and methods for high-resolution mapping of tissue
US9517103B2 (en) 2014-11-19 2016-12-13 Advanced Cardiac Therapeutics, Inc. Medical instruments with multiple temperature sensors
US9566115B2 (en) 2009-07-28 2017-02-14 Neuwave Medical, Inc. Energy delivery systems and uses thereof
US9579030B2 (en) 2011-07-20 2017-02-28 Boston Scientific Scimed, Inc. Percutaneous devices and methods to visualize, target and ablate nerves
US9636164B2 (en) 2015-03-25 2017-05-02 Advanced Cardiac Therapeutics, Inc. Contact sensing systems and methods
US9649156B2 (en) 2010-12-15 2017-05-16 Boston Scientific Scimed, Inc. Bipolar off-wall electrode device for renal nerve ablation
US9668811B2 (en) 2010-11-16 2017-06-06 Boston Scientific Scimed, Inc. Minimally invasive access for renal nerve ablation
US9687166B2 (en) 2013-10-14 2017-06-27 Boston Scientific Scimed, Inc. High resolution cardiac mapping electrode array catheter
US9693821B2 (en) 2013-03-11 2017-07-04 Boston Scientific Scimed, Inc. Medical devices for modulating nerves
US9700372B2 (en) 2002-07-01 2017-07-11 Recor Medical, Inc. Intraluminal methods of ablating nerve tissue
US9707036B2 (en) 2013-06-25 2017-07-18 Boston Scientific Scimed, Inc. Devices and methods for nerve modulation using localized indifferent electrodes
US9713730B2 (en) 2004-09-10 2017-07-25 Boston Scientific Scimed, Inc. Apparatus and method for treatment of in-stent restenosis
US9770606B2 (en) 2013-10-15 2017-09-26 Boston Scientific Scimed, Inc. Ultrasound ablation catheter with cooling infusion and centering basket
US9808311B2 (en) 2013-03-13 2017-11-07 Boston Scientific Scimed, Inc. Deflectable medical devices
US9808300B2 (en) 2006-05-02 2017-11-07 Boston Scientific Scimed, Inc. Control of arterial smooth muscle tone
US9827039B2 (en) 2013-03-15 2017-11-28 Boston Scientific Scimed, Inc. Methods and apparatuses for remodeling tissue of or adjacent to a body passage
US9833283B2 (en) 2013-07-01 2017-12-05 Boston Scientific Scimed, Inc. Medical devices for renal nerve ablation
US9861440B2 (en) 2010-05-03 2018-01-09 Neuwave Medical, Inc. Energy delivery systems and uses thereof
US20180008346A1 (en) * 2016-07-11 2018-01-11 Gyrus Medical Limited System and method for monitoring tissue temperature
US20180008345A1 (en) * 2016-07-11 2018-01-11 Gyrus Medical Limited System and method for monitoring a microwave tissue ablation process
US9895194B2 (en) 2013-09-04 2018-02-20 Boston Scientific Scimed, Inc. Radio frequency (RF) balloon catheter having flushing and cooling capability
US9907609B2 (en) 2014-02-04 2018-03-06 Boston Scientific Scimed, Inc. Alternative placement of thermal sensors on bipolar electrode
US9925001B2 (en) 2013-07-19 2018-03-27 Boston Scientific Scimed, Inc. Spiral bipolar electrode renal denervation balloon
US9943365B2 (en) 2013-06-21 2018-04-17 Boston Scientific Scimed, Inc. Renal denervation balloon catheter with ride along electrode support
US9956033B2 (en) 2013-03-11 2018-05-01 Boston Scientific Scimed, Inc. Medical devices for modulating nerves
US9962223B2 (en) 2013-10-15 2018-05-08 Boston Scientific Scimed, Inc. Medical device balloon
US9974607B2 (en) 2006-10-18 2018-05-22 Vessix Vascular, Inc. Inducing desirable temperature effects on body tissue
US9980766B1 (en) 2014-03-28 2018-05-29 Medtronic Ardian Luxembourg S.A.R.L. Methods and systems for renal neuromodulation
US9987081B1 (en) 2017-04-27 2018-06-05 Iowa Approach, Inc. Systems, devices, and methods for signal generation
US9993178B2 (en) 2016-03-15 2018-06-12 Epix Therapeutics, Inc. Methods of determining catheter orientation
US9999465B2 (en) 2014-10-14 2018-06-19 Iowa Approach, Inc. Method and apparatus for rapid and safe pulmonary vein cardiac ablation
US10022182B2 (en) 2013-06-21 2018-07-17 Boston Scientific Scimed, Inc. Medical devices for renal nerve ablation having rotatable shafts
US10080864B2 (en) 2012-10-19 2018-09-25 Medtronic Ardian Luxembourg S.A.R.L. Packaging for catheter treatment devices and associated devices, systems, and methods
US10085799B2 (en) 2011-10-11 2018-10-02 Boston Scientific Scimed, Inc. Off-wall electrode device and methods for nerve modulation
US10130423B1 (en) 2017-07-06 2018-11-20 Farapulse, Inc. Systems, devices, and methods for focal ablation
US10166062B2 (en) 2014-11-19 2019-01-01 Epix Therapeutics, Inc. High-resolution mapping of tissue with pacing
US10172673B2 (en) 2016-01-05 2019-01-08 Farapulse, Inc. Systems devices, and methods for delivery of pulsed electric field ablative energy to endocardial tissue
US10179020B2 (en) 2010-10-25 2019-01-15 Medtronic Ardian Luxembourg S.A.R.L. Devices, systems and methods for evaluation and feedback of neuromodulation treatment
US10194979B1 (en) 2014-03-28 2019-02-05 Medtronic Ardian Luxembourg S.A.R.L. Methods for catheter-based renal neuromodulation
US10194980B1 (en) 2014-03-28 2019-02-05 Medtronic Ardian Luxembourg S.A.R.L. Methods for catheter-based renal neuromodulation
WO2018187244A3 (en) * 2017-04-03 2019-03-07 Broncus Medical Inc. ELECTROSURGICAL ACCESS SLEEVE
US10265122B2 (en) 2013-03-15 2019-04-23 Boston Scientific Scimed, Inc. Nerve ablation devices and related methods of use
US10271898B2 (en) 2013-10-25 2019-04-30 Boston Scientific Scimed, Inc. Embedded thermocouple in denervation flex circuit
US10322286B2 (en) 2016-01-05 2019-06-18 Farapulse, Inc. Systems, apparatuses and methods for delivery of ablative energy to tissue
US10321946B2 (en) 2012-08-24 2019-06-18 Boston Scientific Scimed, Inc. Renal nerve modulation devices with weeping RF ablation balloons
US10342609B2 (en) 2013-07-22 2019-07-09 Boston Scientific Scimed, Inc. Medical devices for renal nerve ablation
US10363092B2 (en) 2006-03-24 2019-07-30 Neuwave Medical, Inc. Transmission line with heat transfer ability
US10376314B2 (en) 2006-07-14 2019-08-13 Neuwave Medical, Inc. Energy delivery systems and uses thereof
US10398464B2 (en) 2012-09-21 2019-09-03 Boston Scientific Scimed, Inc. System for nerve modulation and innocuous thermal gradient nerve block
US10413357B2 (en) 2013-07-11 2019-09-17 Boston Scientific Scimed, Inc. Medical device with stretchable electrode assemblies
US10433906B2 (en) 2014-06-12 2019-10-08 Farapulse, Inc. Method and apparatus for rapid and selective transurethral tissue ablation
US10507302B2 (en) 2016-06-16 2019-12-17 Farapulse, Inc. Systems, apparatuses, and methods for guide wire delivery
US10512505B2 (en) 2018-05-07 2019-12-24 Farapulse, Inc. Systems, apparatuses and methods for delivery of ablative energy to tissue
US10531917B2 (en) 2016-04-15 2020-01-14 Neuwave Medical, Inc. Systems and methods for energy delivery
US10549127B2 (en) 2012-09-21 2020-02-04 Boston Scientific Scimed, Inc. Self-cooling ultrasound ablation catheter
US10617867B2 (en) 2017-04-28 2020-04-14 Farapulse, Inc. Systems, devices, and methods for delivery of pulsed electric field ablative energy to esophageal tissue
US10624693B2 (en) 2014-06-12 2020-04-21 Farapulse, Inc. Method and apparatus for rapid and selective tissue ablation with cooling
US10625080B1 (en) 2019-09-17 2020-04-21 Farapulse, Inc. Systems, apparatuses, and methods for detecting ectopic electrocardiogram signals during pulsed electric field ablation
US10660702B2 (en) 2016-01-05 2020-05-26 Farapulse, Inc. Systems, devices, and methods for focal ablation
US10660698B2 (en) 2013-07-11 2020-05-26 Boston Scientific Scimed, Inc. Devices and methods for nerve modulation
US10660703B2 (en) 2012-05-08 2020-05-26 Boston Scientific Scimed, Inc. Renal nerve modulation devices
US10667860B2 (en) 2011-12-21 2020-06-02 Neuwave Medical, Inc. Energy delivery systems and uses thereof
US10687892B2 (en) 2018-09-20 2020-06-23 Farapulse, Inc. Systems, apparatuses, and methods for delivery of pulsed electric field ablative energy to endocardial tissue
US10695124B2 (en) 2013-07-22 2020-06-30 Boston Scientific Scimed, Inc. Renal nerve ablation catheter having twist balloon
US10722300B2 (en) 2013-08-22 2020-07-28 Boston Scientific Scimed, Inc. Flexible circuit having improved adhesion to a renal nerve modulation balloon
US10835305B2 (en) 2012-10-10 2020-11-17 Boston Scientific Scimed, Inc. Renal nerve modulation devices and methods
US10842572B1 (en) 2019-11-25 2020-11-24 Farapulse, Inc. Methods, systems, and apparatuses for tracking ablation devices and generating lesion lines
US10874455B2 (en) 2012-03-08 2020-12-29 Medtronic Ardian Luxembourg S.A.R.L. Ovarian neuromodulation and associated systems and methods
US10888373B2 (en) 2017-04-27 2021-01-12 Epix Therapeutics, Inc. Contact assessment between an ablation catheter and tissue
US10893905B2 (en) 2017-09-12 2021-01-19 Farapulse, Inc. Systems, apparatuses, and methods for ventricular focal ablation
US10905494B2 (en) 2011-12-29 2021-02-02 St. Jude Medical, Atrial Fibrillation Division, Inc Flexible conductive polymer based conformable device and method to create linear endocardial lesions
US10945786B2 (en) 2013-10-18 2021-03-16 Boston Scientific Scimed, Inc. Balloon catheters with flexible conducting wires and related methods of use and manufacture
US10952792B2 (en) 2015-10-26 2021-03-23 Neuwave Medical, Inc. Energy delivery systems and uses thereof
US10952790B2 (en) 2013-09-13 2021-03-23 Boston Scientific Scimed, Inc. Ablation balloon with vapor deposited cover layer
US11000679B2 (en) 2014-02-04 2021-05-11 Boston Scientific Scimed, Inc. Balloon protection and rewrapping devices and related methods of use
US11020180B2 (en) 2018-05-07 2021-06-01 Farapulse, Inc. Epicardial ablation catheter
US11033236B2 (en) 2018-05-07 2021-06-15 Farapulse, Inc. Systems, apparatuses, and methods for filtering high voltage noise induced by pulsed electric field ablation
US20210196378A1 (en) * 2018-08-13 2021-07-01 The University Of Sydney Catheter ablation device with temperature monitoring
US11065047B2 (en) 2019-11-20 2021-07-20 Farapulse, Inc. Systems, apparatuses, and methods for protecting electronic components from high power noise induced by high voltage pulses
US11202671B2 (en) 2014-01-06 2021-12-21 Boston Scientific Scimed, Inc. Tear resistant flex circuit assembly
US11219484B2 (en) 2008-10-21 2022-01-11 Microcube, Llc Methods and devices for delivering microwave energy
US11246654B2 (en) 2013-10-14 2022-02-15 Boston Scientific Scimed, Inc. Flexible renal nerve ablation devices and related methods of use and manufacture
US11259869B2 (en) 2014-05-07 2022-03-01 Farapulse, Inc. Methods and apparatus for selective tissue ablation
US11291503B2 (en) * 2008-10-21 2022-04-05 Microcube, Llc Microwave treatment devices and methods
US11338140B2 (en) 2012-03-08 2022-05-24 Medtronic Ardian Luxembourg S.A.R.L. Monitoring of neuromodulation using biomarkers
US11389235B2 (en) 2006-07-14 2022-07-19 Neuwave Medical, Inc. Energy delivery systems and uses thereof
US11426573B2 (en) 2012-08-09 2022-08-30 University Of Iowa Research Foundation Catheters, catheter systems, and methods for puncturing through a tissue structure and ablating a tissue region
US11497541B2 (en) 2019-11-20 2022-11-15 Boston Scientific Scimed, Inc. Systems, apparatuses, and methods for protecting electronic components from high power noise induced by high voltage pulses
US11672596B2 (en) 2018-02-26 2023-06-13 Neuwave Medical, Inc. Energy delivery devices with flexible and adjustable tips
US11832879B2 (en) 2019-03-08 2023-12-05 Neuwave Medical, Inc. Systems and methods for energy delivery
US12042208B2 (en) 2018-05-03 2024-07-23 Boston Scientific Scimed, Inc. Systems, devices, and methods for ablation using surgical clamps

Families Citing this family (66)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7137980B2 (en) 1998-10-23 2006-11-21 Sherwood Services Ag Method and system for controlling output of RF medical generator
US6702811B2 (en) 1999-04-05 2004-03-09 Medtronic, Inc. Ablation catheter assembly with radially decreasing helix and method of use
US7087061B2 (en) * 2002-03-12 2006-08-08 Lithotech Medical Ltd Method for intracorporeal lithotripsy fragmentation and apparatus for its implementation
JP2006525096A (ja) 2003-05-01 2006-11-09 シャーウッド・サービシーズ・アクチェンゲゼルシャフト 電気手術用発生器システムのプログラム及び制御を行う方法及びシステム
US8104956B2 (en) 2003-10-23 2012-01-31 Covidien Ag Thermocouple measurement circuit
US7396336B2 (en) 2003-10-30 2008-07-08 Sherwood Services Ag Switched resonant ultrasonic power amplifier system
US7771411B2 (en) 2004-09-24 2010-08-10 Syntheon, Llc Methods for operating a selective stiffening catheter
US7947039B2 (en) * 2005-12-12 2011-05-24 Covidien Ag Laparoscopic apparatus for performing electrosurgical procedures
CA2574934C (en) * 2006-01-24 2015-12-29 Sherwood Services Ag System and method for closed loop monitoring of monopolar electrosurgical apparatus
US10123683B2 (en) 2006-03-02 2018-11-13 Syntheon, Llc Variably flexible insertion device and method for variably flexing an insertion device
US9814372B2 (en) 2007-06-27 2017-11-14 Syntheon, Llc Torque-transmitting, variably-flexible, locking insertion device and method for operating the insertion device
JP4621621B2 (ja) * 2006-03-31 2011-01-26 株式会社東芝 荷電ビーム描画装置
JP2008235464A (ja) * 2007-03-19 2008-10-02 Toshiba Corp 電子ビーム描画装置
US8262652B2 (en) 2009-01-12 2012-09-11 Tyco Healthcare Group Lp Imaginary impedance process monitoring and intelligent shut-off
US9326819B2 (en) * 2009-04-15 2016-05-03 Medwaves, Inc. Electrically tunable tissue ablation system and method
WO2012116265A2 (en) * 2011-02-24 2012-08-30 MRI Interventions, Inc. Mri-guided catheters
US9375273B2 (en) * 2009-09-18 2016-06-28 Covidien Lp System and method for checking high power microwave ablation system status on startup
US8777963B2 (en) * 2010-02-24 2014-07-15 Lithotech Medical Ltd Method and system for destroying of undesirable formations in mammalian body
US9743980B2 (en) * 2010-02-24 2017-08-29 Safepass Vascular Ltd Method and system for assisting a wire guide to cross occluded ducts
US20110213355A1 (en) * 2010-03-01 2011-09-01 Vivant Medical, Inc. Sensors On Patient Side for a Microwave Generator
MX2013004241A (es) 2010-10-25 2013-05-30 Medtronic Ardian Luxembourg Aparatos de cateter que tienen arreglos de multiples electrodos para neuromodulacion renal y sistemas y metodos asociados.
US20120116486A1 (en) 2010-10-25 2012-05-10 Medtronic Ardian Luxembourg S.A.R.L. Microwave catheter apparatuses, systems, and methods for renal neuromodulation
US20120123326A1 (en) * 2010-11-12 2012-05-17 Christian Steven C Catheter systems with distal end function, such as distal deflection, using remote actuation or low input force
US9192422B2 (en) 2011-07-19 2015-11-24 Covidien Lp System and method of matching impedances of an electrosurgical generator and/or a microwave generator
US9028482B2 (en) 2011-07-19 2015-05-12 Covidien Lp Microwave and RF ablation system and related method for dynamic impedance matching
US8968297B2 (en) 2011-07-19 2015-03-03 Covidien Lp Microwave and RF ablation system and related method for dynamic impedance matching
AU2012303701B2 (en) 2011-08-26 2014-02-27 Symap Medical (Suzhou), Ltd System and method for locating and identifying functional nerves innervating wall of arteries and catheters for same
US9820811B2 (en) 2011-08-26 2017-11-21 Symap Medical (Suzhou), Ltd System and method for mapping the functional nerves innervating the wall of arteries, 3-D mapping and catheters for same
US8702619B2 (en) 2011-08-26 2014-04-22 Symap Holding Limited Mapping sympathetic nerve distribution for renal ablation and catheters for same
US8726496B2 (en) 2011-09-22 2014-05-20 Covidien Lp Technique for remanufacturing a medical sensor
US8692992B2 (en) 2011-09-22 2014-04-08 Covidien Lp Faraday shield integrated into sensor bandage
US8968290B2 (en) 2012-03-14 2015-03-03 Covidien Lp Microwave ablation generator control system
US9190720B2 (en) * 2012-03-23 2015-11-17 Apple Inc. Flexible printed circuit structures
US8888773B2 (en) 2012-05-11 2014-11-18 Medtronic Ardian Luxembourg S.A.R.L. Multi-electrode catheter assemblies for renal neuromodulation and associated systems and methods
CN203138452U (zh) * 2012-08-24 2013-08-21 苏州信迈医疗器械有限公司 一种能够定位或识别位于血管壁内或外膜上的神经的仪器
WO2014064552A1 (en) * 2012-10-26 2014-05-01 Koninklijke Philips N.V. System, catheter and planning method for hyperthermia-adjuvant brachytherapy
US9204921B2 (en) 2012-12-13 2015-12-08 Cook Medical Technologies Llc RF energy controller and method for electrosurgical medical devices
US9364277B2 (en) 2012-12-13 2016-06-14 Cook Medical Technologies Llc RF energy controller and method for electrosurgical medical devices
ES2921176T3 (es) * 2013-02-07 2022-08-19 Shanghai Golden Leaf Med Tec Co Ltd Método, sistema de ablación por radiofrecuencia y dispositivo de ablación por radiofrecuencia del mismo
US10076384B2 (en) 2013-03-08 2018-09-18 Symple Surgical, Inc. Balloon catheter apparatus with microwave emitter
US9179974B2 (en) 2013-03-15 2015-11-10 Medtronic Ardian Luxembourg S.A.R.L. Helical push wire electrode
US9872719B2 (en) 2013-07-24 2018-01-23 Covidien Lp Systems and methods for generating electrosurgical energy using a multistage power converter
US9655670B2 (en) 2013-07-29 2017-05-23 Covidien Lp Systems and methods for measuring tissue impedance through an electrosurgical cable
US20150073515A1 (en) 2013-09-09 2015-03-12 Medtronic Ardian Luxembourg S.a.r.I. Neuromodulation Catheter Devices and Systems Having Energy Delivering Thermocouple Assemblies and Associated Methods
US9622811B2 (en) 2014-02-21 2017-04-18 Warsaw Orthopedic, Inc. Surgical instrument and method
WO2015164280A1 (en) 2014-04-24 2015-10-29 Medtronic Ardian Luxembourg S.A.R.L. Neuromodulation catheters having braided shafts and associated systems and methods
US10016234B2 (en) * 2014-06-05 2018-07-10 St. Jude Medical, Cardiology Division, Inc. Flex tip fluid lumen assembly with thermal sensor
GB201418486D0 (en) * 2014-10-17 2014-12-03 Creo Medical Ltd Cable for conveying radiofrequency and/or microwave frequency energy to an electrosurgical instrument
GB201418474D0 (en) 2014-10-17 2014-12-03 Creo Medical Ltd Electrosurgical apparatus
US20180153436A1 (en) 2015-06-03 2018-06-07 St. Jude Medical International Holding S.À R.L. Active magnetic position sensor
US10751123B2 (en) 2015-10-30 2020-08-25 Washington University Thermoablation probe
ES2581127B2 (es) * 2016-04-13 2017-05-04 Universidad Complutense De Madrid Etiqueta, sistema y método para la detección de objetos a larga distancia
GB2550414A (en) * 2016-05-20 2017-11-22 Creo Medical Ltd Antenna structure
GB2559604A (en) * 2017-02-13 2018-08-15 Creo Medical Ltd Microwave energy transfer component for electrosurgical apparatus
WO2018160848A1 (en) * 2017-03-01 2018-09-07 I.C. Medical, Inc. Ultrapolar telescopic and non-telescopic electrosurgery pencils with argon beam capability and ultrapolar electrosurgery blade assembly
US10751507B2 (en) * 2017-04-10 2020-08-25 Syn Variflex, Llc Thermally controlled variable-flexibility catheters and methods of manufacturing same
GB201708726D0 (en) * 2017-06-01 2017-07-19 Creo Medical Ltd Electrosurgical instrument for ablation and resection
GB2563386A (en) * 2017-06-08 2018-12-19 Creo Medical Ltd Electrosurgical instrument
CN107349010A (zh) * 2017-07-07 2017-11-17 昆山雷盛医疗科技有限公司 射频消融探头及其制备方法
CN109464186B (zh) 2017-09-08 2023-12-22 泽丹医疗股份有限公司 治疗肺部肿瘤的装置和方法
WO2019094090A1 (en) * 2017-11-13 2019-05-16 Cryterion Medical, Inc. Operator preference storage system for intravascular catheter system
EP3809988B1 (en) * 2018-06-21 2023-06-07 Shockwave Medical, Inc. System for treating occlusions in body lumens
CN113164127B (zh) 2018-10-06 2024-07-16 苏州信迈医疗科技股份有限公司 用于标测支配动脉壁功能性神经的系统和方法以及可实现相同功能的3d标测法和导管
US20210128231A1 (en) * 2019-11-04 2021-05-06 Medwaves, Inc. Energy transmitting therapeutic medical device
WO2021108704A1 (en) * 2019-11-27 2021-06-03 Blossom Innovations, LLC Devices, systems and methods for tissue analysis, location determination and tissue ablation
CN110870791B (zh) * 2019-12-04 2021-09-03 上海微创电生理医疗科技股份有限公司 医用介入式针组件与医用介入式导管

Citations (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3309455A (en) * 1964-09-21 1967-03-14 Dow Chemical Co Coaxial cable with insulating conductor supporting layers bonded to the conductors
US4408089A (en) * 1979-11-16 1983-10-04 Nixon Charles E Extremely low-attenuation, extremely low radiation loss flexible coaxial cable for microwave energy in the gigaHertz frequency range
US4583556A (en) * 1982-12-13 1986-04-22 M/A-Com, Inc. Microwave applicator/receiver apparatus
US4776086A (en) * 1986-02-27 1988-10-11 Kasevich Associates, Inc. Method and apparatus for hyperthermia treatment
US5150717A (en) * 1988-11-10 1992-09-29 Arye Rosen Microwave aided balloon angioplasty with guide filament
US5370644A (en) * 1988-11-25 1994-12-06 Sensor Electronics, Inc. Radiofrequency ablation catheter
US5500012A (en) * 1992-07-15 1996-03-19 Angeion Corporation Ablation catheter system
US5540681A (en) * 1992-04-10 1996-07-30 Medtronic Cardiorhythm Method and system for radiofrequency ablation of tissue
US5617854A (en) * 1994-06-22 1997-04-08 Munsif; Anand Shaped catheter device and method
US5642736A (en) * 1992-02-14 1997-07-01 Avitall; Boaz Biplanar deflectable catheter for arrhythmogenic tissue ablation
US5656029A (en) * 1992-12-01 1997-08-12 Cardiac Pathways Corporation Steerable catheter with adjustable bend location and/or radius and method
US5683382A (en) * 1995-05-15 1997-11-04 Arrow International Investment Corp. Microwave antenna catheter
US5702433A (en) * 1995-06-27 1997-12-30 Arrow International Investment Corp. Kink-resistant steerable catheter assembly for microwave ablation
US5738683A (en) * 1994-07-16 1998-04-14 Osypka; Peter Mapping and ablation catheter
US5741249A (en) * 1996-10-16 1998-04-21 Fidus Medical Technology Corporation Anchoring tip assembly for microwave ablation catheter
US5776176A (en) * 1996-06-17 1998-07-07 Urologix Inc. Microwave antenna for arterial for arterial microwave applicator
US5842984A (en) * 1993-12-03 1998-12-01 Avitall; Boaz Mapping and ablation catheter system with locking mechanism
US5849028A (en) * 1997-05-16 1998-12-15 Irvine Biomedical, Inc. Catheter and method for radiofrequency ablation of cardiac tissue
US5863291A (en) * 1996-04-08 1999-01-26 Cardima, Inc. Linear ablation assembly
US5882333A (en) * 1994-05-13 1999-03-16 Cardima, Inc. Catheter with deflectable distal section
US5902251A (en) * 1996-05-06 1999-05-11 Vanhooydonk; Neil C. Transcervical intrauterine applicator for intrauterine hyperthermia
US5957969A (en) * 1993-05-14 1999-09-28 Fidus Medical Technology Corporation Tunable microwave ablation catheter system and method
US6014579A (en) * 1997-07-21 2000-01-11 Cardiac Pathways Corp. Endocardial mapping catheter with movable electrode
US6033403A (en) * 1998-10-08 2000-03-07 Irvine Biomedical, Inc. Long electrode catheter system and methods thereof
US6071280A (en) * 1993-11-08 2000-06-06 Rita Medical Systems, Inc. Multiple electrode ablation apparatus
US6123718A (en) * 1998-11-02 2000-09-26 Polymerex Medical Corp. Balloon catheter
US6190382B1 (en) * 1998-12-14 2001-02-20 Medwaves, Inc. Radio-frequency based catheter system for ablation of body tissues
US20010018596A1 (en) * 1997-02-28 2001-08-30 Selmon Matthew R. Methods and apparatus for treating vascular occlusions
US6319250B1 (en) * 1998-11-23 2001-11-20 C.R. Bard, Inc Tricuspid annular grasp catheter
US6383182B1 (en) * 1998-10-23 2002-05-07 Afx Inc. Directional microwave ablation instrument with off-set energy delivery portion
US20020087151A1 (en) * 2000-12-29 2002-07-04 Afx, Inc. Tissue ablation apparatus with a sliding ablation instrument and method
US6527769B2 (en) * 1998-03-02 2003-03-04 Atrionix, Inc. Tissue ablation system and method for forming long linear lesion
US6592581B2 (en) * 1998-05-05 2003-07-15 Cardiac Pacemakers, Inc. Preformed steerable catheter with movable outer sleeve and method for use
US6610058B2 (en) * 2001-05-02 2003-08-26 Cardiac Pacemakers, Inc. Dual-profile steerable catheter
US6669692B1 (en) * 2000-08-21 2003-12-30 Biosense Webster, Inc. Ablation catheter with cooled linear electrode
US20050055019A1 (en) * 2003-09-05 2005-03-10 Medtronic, Inc. RF ablation catheter including a virtual electrode assembly
US20050090880A1 (en) * 2002-03-20 2005-04-28 Fogazzi Di Venturelli Andrea &C. S.N.C. Catheter with flexible cooled electrode
US6941953B2 (en) * 2003-02-20 2005-09-13 Medwaves, Inc. Preformed catheter set for use with a linear ablation system to produce ablation lines in the left and right atrium for treatment of atrial fibrillation
US20050222563A1 (en) * 2004-03-31 2005-10-06 Mcdaniel Benjamin D Catheter for circumferential ablation at or near a pulmonary vein
US7004938B2 (en) * 2001-11-29 2006-02-28 Medwaves, Inc. Radio-frequency-based catheter system with improved deflection and steering mechanisms
US7070595B2 (en) * 1998-12-14 2006-07-04 Medwaves, Inc. Radio-frequency based catheter system and method for ablating biological tissues
US7229450B1 (en) * 2003-02-11 2007-06-12 Pacesetter, Inc. Kink resistant introducer with mapping capabilities
US20090082762A1 (en) * 2007-09-20 2009-03-26 Ormsby Theodore C Radio frequency energy transmission device for the ablation of biological tissues
US7594913B2 (en) * 1998-12-14 2009-09-29 Medwaves, Inc. Radio-frequency based catheter system and method for ablating biological tissues

Family Cites Families (68)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US595796A (en) 1897-12-21 Wrench
US2847990A (en) * 1956-03-20 1958-08-19 Ayre James Ernest Instrument for obtaining cells for cytodiagnosis
US3058473A (en) * 1959-11-27 1962-10-16 Alfred E Whitchead Remotely directing catheters and tools
US3552384A (en) * 1967-07-03 1971-01-05 American Hospital Supply Corp Controllable tip guide body and catheter
US3521620A (en) * 1967-10-30 1970-07-28 William A Cook Vascular coil spring guide with bendable tip
US4204549A (en) * 1977-12-12 1980-05-27 Rca Corporation Coaxial applicator for microwave hyperthermia
US4271848A (en) * 1979-01-11 1981-06-09 Bio Systems Design, Corp. Apparatus for electromagnetic radiation of living tissue and the like
US5370675A (en) * 1992-08-12 1994-12-06 Vidamed, Inc. Medical probe device and method
US4723936A (en) * 1986-07-22 1988-02-09 Versaflex Delivery Systems Inc. Steerable catheter
US4906230A (en) * 1987-06-30 1990-03-06 Baxter Travenol Laboratories, Inc. Steerable catheter tip
US4960134A (en) * 1988-11-18 1990-10-02 Webster Wilton W Jr Steerable catheter
CA2089739A1 (en) * 1990-09-14 1992-03-15 John H. Burton Combined hyperthermia and dilation catheter
US5370677A (en) * 1992-03-06 1994-12-06 Urologix, Inc. Gamma matched, helical dipole microwave antenna with tubular-shaped capacitor
US5413588A (en) * 1992-03-06 1995-05-09 Urologix, Inc. Device and method for asymmetrical thermal therapy with helical dipole microwave antenna
US5275597A (en) * 1992-05-18 1994-01-04 Baxter International Inc. Percutaneous transluminal catheter and transmitter therefor
US5346392A (en) * 1992-07-30 1994-09-13 Kim Jong Il Cigarette-shaped gas lighter
US5298682A (en) * 1992-08-20 1994-03-29 Wireworld By David Salz, Inc. Optimized symmetrical coaxial cable
US6161543A (en) * 1993-02-22 2000-12-19 Epicor, Inc. Methods of epicardial ablation for creating a lesion around the pulmonary veins
US5476495A (en) * 1993-03-16 1995-12-19 Ep Technologies, Inc. Cardiac mapping and ablation systems
US5656796A (en) * 1993-04-26 1997-08-12 Fmc Corp. High energy flexible coaxial cable and connections
US5545193A (en) * 1993-10-15 1996-08-13 Ep Technologies, Inc. Helically wound radio-frequency emitting electrodes for creating lesions in body tissue
US5462545A (en) * 1994-01-31 1995-10-31 New England Medical Center Hospitals, Inc. Catheter electrodes
US5885278A (en) * 1994-10-07 1999-03-23 E.P. Technologies, Inc. Structures for deploying movable electrode elements
US5857997A (en) * 1994-11-14 1999-01-12 Heart Rhythm Technologies, Inc. Catheter for electrophysiological procedures
US5697958A (en) * 1995-06-07 1997-12-16 Intermedics, Inc. Electromagnetic noise detector for implantable medical devices
WO1996041654A1 (en) 1995-06-12 1996-12-27 Cordis Webster, Inc. Catheter with an electromagnetic guidance sensor
US5788692A (en) 1995-06-30 1998-08-04 Fidus Medical Technology Corporation Mapping ablation catheter
US5810717A (en) * 1995-09-22 1998-09-22 Mitsubishi Cable Industries, Ltd. Bending mechanism and stereoscope using same
US5837001A (en) * 1995-12-08 1998-11-17 C. R. Bard Radio frequency energy delivery system for multipolar electrode catheters
US5800482A (en) * 1996-03-06 1998-09-01 Cardiac Pathways Corporation Apparatus and method for linear lesion ablation
US6032077A (en) * 1996-03-06 2000-02-29 Cardiac Pathways Corporation Ablation catheter with electrical coupling via foam drenched with a conductive fluid
US5755760A (en) * 1996-03-11 1998-05-26 Medtronic, Inc. Deflectable catheter
US5904709A (en) * 1996-04-17 1999-05-18 The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration Microwave treatment for cardiac arrhythmias
US5752951A (en) * 1996-07-02 1998-05-19 Yanik; Gary W. Shielded monopolar electrosurgical apparatus
US5800494A (en) * 1996-08-20 1998-09-01 Fidus Medical Technology Corporation Microwave ablation catheters having antennas with distal fire capabilities
US5893885A (en) * 1996-11-01 1999-04-13 Cordis Webster, Inc. Multi-electrode ablation catheter
US5785706A (en) * 1996-11-18 1998-07-28 Daig Corporation Nonsurgical mapping and treatment of cardiac arrhythmia using a catheter contained within a guiding introducer containing openings
US5904667A (en) * 1997-03-17 1999-05-18 C.R. Bard, Inc. Rotatable control mechanism for steerable catheter
US5876373A (en) * 1997-04-04 1999-03-02 Eclipse Surgical Technologies, Inc. Steerable catheter
US5971983A (en) * 1997-05-09 1999-10-26 The Regents Of The University Of California Tissue ablation device and method of use
US6123699A (en) 1997-09-05 2000-09-26 Cordis Webster, Inc. Omni-directional steerable catheter
US5897529A (en) * 1997-09-05 1999-04-27 Cordis Webster, Inc. Steerable deflectable catheter having improved flexibility
US6183463B1 (en) * 1997-12-01 2001-02-06 Cordis Webster, Inc. Bidirectional steerable cathether with bidirectional control handle
US6067475A (en) * 1998-11-05 2000-05-23 Urologix, Inc. Microwave energy delivery system including high performance dual directional coupler for precisely measuring forward and reverse microwave power during thermal therapy
US20070066972A1 (en) * 2001-11-29 2007-03-22 Medwaves, Inc. Ablation catheter apparatus with one or more electrodes
US6267746B1 (en) * 1999-03-22 2001-07-31 Biosense Webster, Inc. Multi-directional steerable catheters and control handles
EP1092449A1 (en) * 1999-04-30 2001-04-18 Usaminanotechnology, Inc. Catheter and guide wire
US6277113B1 (en) * 1999-05-28 2001-08-21 Afx, Inc. Monopole tip for ablation catheter and methods for using same
GB9912625D0 (en) 1999-05-28 1999-07-28 Gyrus Medical Ltd An electrosurgical generator and system
US20010007940A1 (en) * 1999-06-21 2001-07-12 Hosheng Tu Medical device having ultrasound imaging and therapeutic means
US6254568B1 (en) * 1999-08-10 2001-07-03 Biosense Webster, Inc. Deflectable catheter with straightening element
US6230060B1 (en) * 1999-10-22 2001-05-08 Daniel D. Mawhinney Single integrated structural unit for catheter incorporating a microwave antenna
US7033352B1 (en) * 2000-01-18 2006-04-25 Afx, Inc. Flexible ablation instrument
US6663622B1 (en) 2000-02-11 2003-12-16 Iotek, Inc. Surgical devices and methods for use in tissue ablation procedures
US6673068B1 (en) * 2000-04-12 2004-01-06 Afx, Inc. Electrode arrangement for use in a medical instrument
US6582536B2 (en) 2000-04-24 2003-06-24 Biotran Corporation Inc. Process for producing steerable sheath catheters
US6475214B1 (en) 2000-05-01 2002-11-05 Biosense Webster, Inc. Catheter with enhanced ablation electrode
DK1151728T3 (da) 2000-05-03 2006-11-27 Joshua Dr Friedman Fremgangsmåde og opvarmningsindretning til forvarmning af dentale materialer
JP3521253B2 (ja) * 2000-05-18 2004-04-19 株式会社東北テクノアーチ 生体用形状記憶合金
US6893155B2 (en) * 2000-09-30 2005-05-17 Dolores C. Kaiser Cooking thermometer with audible alarm
US6878147B2 (en) * 2001-11-02 2005-04-12 Vivant Medical, Inc. High-strength microwave antenna assemblies
US7194297B2 (en) * 2001-11-13 2007-03-20 Boston Scientific Scimed, Inc. Impedance-matching apparatus and construction for intravascular device
US6706040B2 (en) * 2001-11-23 2004-03-16 Medlennium Technologies, Inc. Invasive therapeutic probe
US7259640B2 (en) * 2001-12-03 2007-08-21 Microfabrica Miniature RF and microwave components and methods for fabricating such components
US6907298B2 (en) * 2002-01-09 2005-06-14 Medtronic, Inc. Method and apparatus for imparting curves in implantable elongated medical instruments
AU2003294226A1 (en) * 2002-09-20 2004-04-23 Flowmedica, Inc. Method and apparatus for intra aortic substance delivery to a branch vessel
US7736362B2 (en) * 2003-09-15 2010-06-15 Boston Scientific Scimed, Inc. Catheter balloons
US7331959B2 (en) * 2004-05-27 2008-02-19 St. Jude Medical, Atrial Fibrillation Division, Inc. Catheter electrode and rail system for cardiac ablation

Patent Citations (45)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3309455A (en) * 1964-09-21 1967-03-14 Dow Chemical Co Coaxial cable with insulating conductor supporting layers bonded to the conductors
US4408089A (en) * 1979-11-16 1983-10-04 Nixon Charles E Extremely low-attenuation, extremely low radiation loss flexible coaxial cable for microwave energy in the gigaHertz frequency range
US4583556A (en) * 1982-12-13 1986-04-22 M/A-Com, Inc. Microwave applicator/receiver apparatus
US4776086A (en) * 1986-02-27 1988-10-11 Kasevich Associates, Inc. Method and apparatus for hyperthermia treatment
US5150717A (en) * 1988-11-10 1992-09-29 Arye Rosen Microwave aided balloon angioplasty with guide filament
US5370644A (en) * 1988-11-25 1994-12-06 Sensor Electronics, Inc. Radiofrequency ablation catheter
US5642736A (en) * 1992-02-14 1997-07-01 Avitall; Boaz Biplanar deflectable catheter for arrhythmogenic tissue ablation
US5540681A (en) * 1992-04-10 1996-07-30 Medtronic Cardiorhythm Method and system for radiofrequency ablation of tissue
US5500012A (en) * 1992-07-15 1996-03-19 Angeion Corporation Ablation catheter system
US5656029A (en) * 1992-12-01 1997-08-12 Cardiac Pathways Corporation Steerable catheter with adjustable bend location and/or radius and method
US5957969A (en) * 1993-05-14 1999-09-28 Fidus Medical Technology Corporation Tunable microwave ablation catheter system and method
US6071280A (en) * 1993-11-08 2000-06-06 Rita Medical Systems, Inc. Multiple electrode ablation apparatus
US5842984A (en) * 1993-12-03 1998-12-01 Avitall; Boaz Mapping and ablation catheter system with locking mechanism
US5882333A (en) * 1994-05-13 1999-03-16 Cardima, Inc. Catheter with deflectable distal section
US5617854A (en) * 1994-06-22 1997-04-08 Munsif; Anand Shaped catheter device and method
US5738683A (en) * 1994-07-16 1998-04-14 Osypka; Peter Mapping and ablation catheter
US5683382A (en) * 1995-05-15 1997-11-04 Arrow International Investment Corp. Microwave antenna catheter
US5702433A (en) * 1995-06-27 1997-12-30 Arrow International Investment Corp. Kink-resistant steerable catheter assembly for microwave ablation
US5863291A (en) * 1996-04-08 1999-01-26 Cardima, Inc. Linear ablation assembly
US5902251A (en) * 1996-05-06 1999-05-11 Vanhooydonk; Neil C. Transcervical intrauterine applicator for intrauterine hyperthermia
US5776176A (en) * 1996-06-17 1998-07-07 Urologix Inc. Microwave antenna for arterial for arterial microwave applicator
US5741249A (en) * 1996-10-16 1998-04-21 Fidus Medical Technology Corporation Anchoring tip assembly for microwave ablation catheter
US20010018596A1 (en) * 1997-02-28 2001-08-30 Selmon Matthew R. Methods and apparatus for treating vascular occlusions
US5849028A (en) * 1997-05-16 1998-12-15 Irvine Biomedical, Inc. Catheter and method for radiofrequency ablation of cardiac tissue
US6014579A (en) * 1997-07-21 2000-01-11 Cardiac Pathways Corp. Endocardial mapping catheter with movable electrode
US6527769B2 (en) * 1998-03-02 2003-03-04 Atrionix, Inc. Tissue ablation system and method for forming long linear lesion
US6592581B2 (en) * 1998-05-05 2003-07-15 Cardiac Pacemakers, Inc. Preformed steerable catheter with movable outer sleeve and method for use
US6033403A (en) * 1998-10-08 2000-03-07 Irvine Biomedical, Inc. Long electrode catheter system and methods thereof
US6383182B1 (en) * 1998-10-23 2002-05-07 Afx Inc. Directional microwave ablation instrument with off-set energy delivery portion
US6123718A (en) * 1998-11-02 2000-09-26 Polymerex Medical Corp. Balloon catheter
US6319250B1 (en) * 1998-11-23 2001-11-20 C.R. Bard, Inc Tricuspid annular grasp catheter
US7070595B2 (en) * 1998-12-14 2006-07-04 Medwaves, Inc. Radio-frequency based catheter system and method for ablating biological tissues
US6190382B1 (en) * 1998-12-14 2001-02-20 Medwaves, Inc. Radio-frequency based catheter system for ablation of body tissues
US7594913B2 (en) * 1998-12-14 2009-09-29 Medwaves, Inc. Radio-frequency based catheter system and method for ablating biological tissues
US6663625B1 (en) * 1998-12-14 2003-12-16 Theodore C. Ormsby Radio-frequency based catheter system and hollow co-axial cable for ablation of body tissues
US6669692B1 (en) * 2000-08-21 2003-12-30 Biosense Webster, Inc. Ablation catheter with cooled linear electrode
US20020087151A1 (en) * 2000-12-29 2002-07-04 Afx, Inc. Tissue ablation apparatus with a sliding ablation instrument and method
US6610058B2 (en) * 2001-05-02 2003-08-26 Cardiac Pacemakers, Inc. Dual-profile steerable catheter
US7004938B2 (en) * 2001-11-29 2006-02-28 Medwaves, Inc. Radio-frequency-based catheter system with improved deflection and steering mechanisms
US20050090880A1 (en) * 2002-03-20 2005-04-28 Fogazzi Di Venturelli Andrea &C. S.N.C. Catheter with flexible cooled electrode
US7229450B1 (en) * 2003-02-11 2007-06-12 Pacesetter, Inc. Kink resistant introducer with mapping capabilities
US6941953B2 (en) * 2003-02-20 2005-09-13 Medwaves, Inc. Preformed catheter set for use with a linear ablation system to produce ablation lines in the left and right atrium for treatment of atrial fibrillation
US20050055019A1 (en) * 2003-09-05 2005-03-10 Medtronic, Inc. RF ablation catheter including a virtual electrode assembly
US20050222563A1 (en) * 2004-03-31 2005-10-06 Mcdaniel Benjamin D Catheter for circumferential ablation at or near a pulmonary vein
US20090082762A1 (en) * 2007-09-20 2009-03-26 Ormsby Theodore C Radio frequency energy transmission device for the ablation of biological tissues

Cited By (380)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20080015570A1 (en) * 1998-12-14 2008-01-17 Ormsby Theodore C Hollow conductive coaxial cable for radio frequency based tissue ablation system
US8308722B2 (en) 1998-12-14 2012-11-13 Medwaves, Inc. Hollow conductive coaxial cable for radio frequency based tissue ablation system
US20060142752A1 (en) * 2001-11-29 2006-06-29 Ormsby Theodore C Radio-frequency-based catheter system with improved deflection and steering mechanisms
US8152799B2 (en) 2001-11-29 2012-04-10 Medwaves, Inc. Radio frequency-based catheter system with improved deflection and steering mechanisms
US20110009858A1 (en) * 2001-11-29 2011-01-13 Medwaves, Inc. Radio frequency-based catheter system with improved deflection and steering mechanisms
US7815637B2 (en) 2001-11-29 2010-10-19 Ormsby Theodore C Radio-frequency-based catheter system with improved deflection and steering mechanisms
US8774922B2 (en) 2002-04-08 2014-07-08 Medtronic Ardian Luxembourg S.A.R.L. Catheter apparatuses having expandable balloons for renal neuromodulation and associated systems and methods
US10130792B2 (en) 2002-04-08 2018-11-20 Medtronic Ardian Luxembourg S.A.R.L. Methods for therapeutic renal neuromodulation using neuromodulatory agents or drugs
US9308044B2 (en) 2002-04-08 2016-04-12 Medtronic Ardian Luxembourg S.A.R.L. Methods for therapeutic renal neuromodulation
US9289255B2 (en) 2002-04-08 2016-03-22 Medtronic Ardian Luxembourg S.A.R.L. Methods and apparatus for renal neuromodulation
US9314630B2 (en) 2002-04-08 2016-04-19 Medtronic Ardian Luxembourg S.A.R.L. Renal neuromodulation for treatment of patients
US9320561B2 (en) 2002-04-08 2016-04-26 Medtronic Ardian Luxembourg S.A.R.L. Methods for bilateral renal neuromodulation
US9326817B2 (en) 2002-04-08 2016-05-03 Medtronic Ardian Luxembourg S.A.R.L. Methods for treating heart arrhythmia
US8784463B2 (en) 2002-04-08 2014-07-22 Medtronic Ardian Luxembourg S.A.R.L. Methods for thermally-induced renal neuromodulation
US9265558B2 (en) 2002-04-08 2016-02-23 Medtronic Ardian Luxembourg S.A.R.L. Methods for bilateral renal neuromodulation
US8771252B2 (en) 2002-04-08 2014-07-08 Medtronic Ardian Luxembourg S.A.R.L. Methods and devices for renal nerve blocking
US9327122B2 (en) 2002-04-08 2016-05-03 Medtronic Ardian Luxembourg S.A.R.L. Methods for catheter-based renal neuromodulation
US9364280B2 (en) 2002-04-08 2016-06-14 Medtronic Ardian Luxembourg S.A.R.L. Methods and apparatus for pulsed electric field neuromodulation via an intra-to-extravascular approach
US10376312B2 (en) 2002-04-08 2019-08-13 Medtronic Ardian Luxembourg S.A.R.L. Methods and apparatus for monopolar renal neuromodulation
US9192715B2 (en) 2002-04-08 2015-11-24 Medtronic Ardian Luxembourg S.A.R.L. Methods for renal nerve blocking
US10293190B2 (en) 2002-04-08 2019-05-21 Medtronic Ardian Luxembourg S.A.R.L. Thermally-induced renal neuromodulation and associated systems and methods
US10376516B2 (en) 2002-04-08 2019-08-13 Medtronic Ardian Luxembourg S.A.R.L. Methods and devices for renal nerve blocking
US10272246B2 (en) 2002-04-08 2019-04-30 Medtronic Adrian Luxembourg S.a.r.l Methods for extravascular renal neuromodulation
US10245429B2 (en) 2002-04-08 2019-04-02 Medtronic Ardian Luxembourg S.A.R.L. Methods and apparatus for renal neuromodulation
US20070129760A1 (en) * 2002-04-08 2007-06-07 Ardian, Inc. Methods and apparatus for intravasculary-induced neuromodulation or denervation
US9439726B2 (en) 2002-04-08 2016-09-13 Medtronic Ardian Luxembourg S.A.R.L. Methods for therapeutic renal neuromodulation
US10420606B2 (en) 2002-04-08 2019-09-24 Medtronic Ardian Luxembourg S.A.R.L. Methods and apparatus for performing a non-continuous circumferential treatment of a body lumen
US9445867B1 (en) 2002-04-08 2016-09-20 Medtronic Ardian Luxembourg S.A.R.L. Methods for renal neuromodulation via catheters having expandable treatment members
US20060276852A1 (en) * 2002-04-08 2006-12-07 Ardian, Inc. Methods and apparatus for treating hypertension
US10441356B2 (en) 2002-04-08 2019-10-15 Medtronic Ardian Luxembourg S.A.R.L. Methods for renal neuromodulation via neuromodulatory agents
US9456869B2 (en) 2002-04-08 2016-10-04 Medtronic Ardian Luxembourg S.A.R.L. Methods for bilateral renal neuromodulation
US9186213B2 (en) 2002-04-08 2015-11-17 Medtronic Ardian Luxembourg S.A.R.L. Methods for renal neuromodulation
US10179027B2 (en) 2002-04-08 2019-01-15 Medtronic Ardian Luxembourg S.A.R.L. Catheter apparatuses having expandable baskets for renal neuromodulation and associated systems and methods
US20110208096A1 (en) * 2002-04-08 2011-08-25 Ardian, Inc. Methods and apparatus for thermally-induced renal neuromodulation
US9186198B2 (en) 2002-04-08 2015-11-17 Medtronic Ardian Luxembourg S.A.R.L. Ultrasound apparatuses for thermally-induced renal neuromodulation and associated systems and methods
US10179028B2 (en) 2002-04-08 2019-01-15 Medtronic Ardian Luxembourg S.A.R.L. Methods for treating patients via renal neuromodulation
US9463066B2 (en) 2002-04-08 2016-10-11 Medtronic Ardian Luxembourg S.A.R.L. Methods for renal neuromodulation
US8131372B2 (en) 2002-04-08 2012-03-06 Ardian, Inc. Renal nerve stimulation method for treatment of patients
US8131371B2 (en) 2002-04-08 2012-03-06 Ardian, Inc. Methods and apparatus for monopolar renal neuromodulation
US9468497B2 (en) 2002-04-08 2016-10-18 Medtronic Ardian Luxembourg S.A.R.L. Methods for monopolar renal neuromodulation
US8145316B2 (en) 2002-04-08 2012-03-27 Ardian, Inc. Methods and apparatus for renal neuromodulation
US8145317B2 (en) 2002-04-08 2012-03-27 Ardian, Inc. Methods for renal neuromodulation
US8150520B2 (en) 2002-04-08 2012-04-03 Ardian, Inc. Methods for catheter-based renal denervation
US8150519B2 (en) 2002-04-08 2012-04-03 Ardian, Inc. Methods and apparatus for bilateral renal neuromodulation
US8150518B2 (en) 2002-04-08 2012-04-03 Ardian, Inc. Renal nerve stimulation method and apparatus for treatment of patients
US20060265014A1 (en) * 2002-04-08 2006-11-23 Ardian, Inc. Methods and apparatus for bilateral renal neuromodulation
US10179235B2 (en) 2002-04-08 2019-01-15 Medtronic Ardian Luxembourg S.A.R.L. Methods and apparatus for bilateral renal neuromodulation
US9474563B2 (en) 2002-04-08 2016-10-25 Medtronic Ardian Luxembourg S.A.R.L. Methods for renal neuromodulation
US8175711B2 (en) 2002-04-08 2012-05-08 Ardian, Inc. Methods for treating a condition or disease associated with cardio-renal function
US9486270B2 (en) 2002-04-08 2016-11-08 Medtronic Ardian Luxembourg S.A.R.L. Methods and apparatus for bilateral renal neuromodulation
US9138281B2 (en) 2002-04-08 2015-09-22 Medtronic Ardian Luxembourg S.A.R.L. Methods for bilateral renal neuromodulation via catheter apparatuses having expandable baskets
US20060265015A1 (en) * 2002-04-08 2006-11-23 Ardian, Inc. Methods and apparatus for monopolar renal neuromodulation
US9131978B2 (en) 2002-04-08 2015-09-15 Medtronic Ardian Luxembourg S.A.R.L. Methods for bilateral renal neuromodulation
US9757192B2 (en) 2002-04-08 2017-09-12 Medtronic Ardian Luxembourg S.A.R.L. Renal neuromodulation for treatment of patients
US9125661B2 (en) 2002-04-08 2015-09-08 Medtronic Ardian Luxembourg S.A.R.L. Methods and apparatus for renal neuromodulation
US8454594B2 (en) 2002-04-08 2013-06-04 Medtronic Ardian Luxembourg S.A.R.L. Apparatus for performing a non-continuous circumferential treatment of a body lumen
US9636174B2 (en) 2002-04-08 2017-05-02 Medtronic Ardian Luxembourg S.A.R.L. Methods for therapeutic renal neuromodulation
US10124195B2 (en) 2002-04-08 2018-11-13 Medtronic Ardian Luxembourg S.A.R.L. Methods for thermally-induced renal neuromodulation
US10111707B2 (en) 2002-04-08 2018-10-30 Medtronic Ardian Luxembourg S.A.R.L. Renal neuromodulation for treatment of human patients
US8548600B2 (en) 2002-04-08 2013-10-01 Medtronic Ardian Luxembourg S.A.R.L. Apparatuses for renal neuromodulation and associated systems and methods
US8551069B2 (en) 2002-04-08 2013-10-08 Medtronic Adrian Luxembourg S.a.r.l. Methods and apparatus for treating contrast nephropathy
US8620423B2 (en) 2002-04-08 2013-12-31 Medtronic Ardian Luxembourg S.A.R.L. Methods for thermal modulation of nerves contributing to renal function
US8626300B2 (en) 2002-04-08 2014-01-07 Medtronic Ardian Luxembourg S.A.R.L. Methods and apparatus for thermally-induced renal neuromodulation
US10105180B2 (en) 2002-04-08 2018-10-23 Medtronic Ardian Luxembourg S.A.R.L. Methods and apparatus for intravascularly-induced neuromodulation
US9675413B2 (en) 2002-04-08 2017-06-13 Medtronic Ardian Luxembourg S.A.R.L. Methods and apparatus for renal neuromodulation
US10039596B2 (en) 2002-04-08 2018-08-07 Medtronic Ardian Luxembourg S.A.R.L. Apparatus for renal neuromodulation via an intra-to-extravascular approach
US10376311B2 (en) 2002-04-08 2019-08-13 Medtronic Ardian Luxembourg S.A.R.L. Methods and apparatus for intravascularly-induced neuromodulation
US8684998B2 (en) 2002-04-08 2014-04-01 Medtronic Ardian Luxembourg S.A.R.L. Methods for inhibiting renal nerve activity
US8721637B2 (en) 2002-04-08 2014-05-13 Medtronic Ardian Luxembourg S.A.R.L. Methods and apparatus for performing renal neuromodulation via catheter apparatuses having inflatable balloons
US8728137B2 (en) 2002-04-08 2014-05-20 Medtronic Ardian Luxembourg S.A.R.L. Methods for thermally-induced renal neuromodulation
US10034708B2 (en) 2002-04-08 2018-07-31 Medtronic Ardian Luxembourg S.A.R.L. Methods and apparatus for thermally-induced renal neuromodulation
US8728138B2 (en) 2002-04-08 2014-05-20 Medtronic Ardian Luxembourg S.A.R.L. Methods for thermally-induced renal neuromodulation
US8740896B2 (en) 2002-04-08 2014-06-03 Medtronic Ardian Luxembourg S.A.R.L. Methods and apparatus for performing renal neuromodulation via catheter apparatuses having inflatable balloons
US8768470B2 (en) 2002-04-08 2014-07-01 Medtronic Ardian Luxembourg S.A.R.L. Methods for monitoring renal neuromodulation
US9308043B2 (en) 2002-04-08 2016-04-12 Medtronic Ardian Luxembourg S.A.R.L. Methods for monopolar renal neuromodulation
US8774913B2 (en) 2002-04-08 2014-07-08 Medtronic Ardian Luxembourg S.A.R.L. Methods and apparatus for intravasculary-induced neuromodulation
US9072527B2 (en) 2002-04-08 2015-07-07 Medtronic Ardian Luxembourg S.A.R.L. Apparatuses and methods for renal neuromodulation
US20060041277A1 (en) * 2002-04-08 2006-02-23 Mark Deem Methods and apparatus for renal neuromodulation
US9707035B2 (en) 2002-04-08 2017-07-18 Medtronic Ardian Luxembourg S.A.R.L. Methods for catheter-based renal neuromodulation
US9731132B2 (en) 2002-04-08 2017-08-15 Medtronic Ardian Luxembourg S.A.R.L. Methods for renal neuromodulation
US9968611B2 (en) 2002-04-08 2018-05-15 Medtronic Ardian Luxembourg S.A.R.L. Methods and devices for renal nerve blocking
US10850091B2 (en) 2002-04-08 2020-12-01 Medtronic Ardian Luxembourg S.A.R.L. Methods and apparatus for bilateral renal neuromodulation
US8818514B2 (en) 2002-04-08 2014-08-26 Medtronic Ardian Luxembourg S.A.R.L. Methods for intravascularly-induced neuromodulation
US8845629B2 (en) 2002-04-08 2014-09-30 Medtronic Ardian Luxembourg S.A.R.L. Ultrasound apparatuses for thermally-induced renal neuromodulation
US8852163B2 (en) 2002-04-08 2014-10-07 Medtronic Ardian Luxembourg S.A.R.L. Renal neuromodulation via drugs and neuromodulatory agents and associated systems and methods
US9956410B2 (en) 2002-04-08 2018-05-01 Medtronic Ardian Luxembourg S.A.R.L. Methods and apparatus for renal neuromodulation
US8880186B2 (en) 2002-04-08 2014-11-04 Medtronic Ardian Luxembourg S.A.R.L. Renal neuromodulation for treatment of patients with chronic heart failure
US9023037B2 (en) 2002-04-08 2015-05-05 Medtronic Ardian Luxembourg S.A.R.L. Balloon catheter apparatus for renal neuromodulation
US9743983B2 (en) 2002-04-08 2017-08-29 Medtronic Ardian Luxembourg S.A.R.L. Renal neuromodulation for treatment of patients
US9907611B2 (en) 2002-04-08 2018-03-06 Medtronic Ardian Luxembourg S.A.R.L. Renal neuromodulation for treatment of patients
US9895195B2 (en) 2002-04-08 2018-02-20 Medtronic Ardian Luxembourg S.A.R.L. Methods for therapeutic renal neuromodulation
US11033328B2 (en) 2002-04-08 2021-06-15 Medtronic Ardian Luxembourg S.A.R.L. Methods and apparatus for renal neuromodulation
US8934978B2 (en) 2002-04-08 2015-01-13 Medtronic Ardian Luxembourg S.A.R.L. Methods and apparatus for renal neuromodulation
US9757193B2 (en) 2002-04-08 2017-09-12 Medtronic Ardian Luxembourg S.A.R.L. Balloon catheter apparatus for renal neuromodulation
US8948865B2 (en) 2002-04-08 2015-02-03 Medtronic Ardian Luxembourg S.A.R.L. Methods for treating heart arrhythmia
US9827041B2 (en) 2002-04-08 2017-11-28 Medtronic Ardian Luxembourg S.A.R.L. Balloon catheter apparatuses for renal denervation
US9827040B2 (en) 2002-04-08 2017-11-28 Medtronic Adrian Luxembourg S.a.r.l. Methods and apparatus for intravascularly-induced neuromodulation
US8958871B2 (en) 2002-04-08 2015-02-17 Medtronic Ardian Luxembourg S.A.R.L. Methods and apparatus for pulsed electric field neuromodulation via an intra-to-extravascular approach
US9814873B2 (en) 2002-04-08 2017-11-14 Medtronic Ardian Luxembourg S.A.R.L. Methods and apparatus for bilateral renal neuromodulation
US8986294B2 (en) 2002-04-08 2015-03-24 Medtronic Ardian Luxembourg S.a.rl. Apparatuses for thermally-induced renal neuromodulation
US8983595B2 (en) 2002-04-08 2015-03-17 Medtronic Ardian Luxembourg S.A.R.L. Renal neuromodulation for treatment of patients with chronic heart failure
US9700372B2 (en) 2002-07-01 2017-07-11 Recor Medical, Inc. Intraluminal methods of ablating nerve tissue
US9707034B2 (en) 2002-07-01 2017-07-18 Recor Medical, Inc. Intraluminal method and apparatus for ablating nerve tissue
US10188457B2 (en) 2003-09-12 2019-01-29 Vessix Vascular, Inc. Selectable eccentric remodeling and/or ablation
US9510901B2 (en) 2003-09-12 2016-12-06 Vessix Vascular, Inc. Selectable eccentric remodeling and/or ablation
US9125666B2 (en) 2003-09-12 2015-09-08 Vessix Vascular, Inc. Selectable eccentric remodeling and/or ablation of atherosclerotic material
US8939970B2 (en) 2004-09-10 2015-01-27 Vessix Vascular, Inc. Tuned RF energy and electrical tissue characterization for selective treatment of target tissues
US9125667B2 (en) 2004-09-10 2015-09-08 Vessix Vascular, Inc. System for inducing desirable temperature effects on body tissue
US9713730B2 (en) 2004-09-10 2017-07-25 Boston Scientific Scimed, Inc. Apparatus and method for treatment of in-stent restenosis
US8433423B2 (en) 2004-10-05 2013-04-30 Ardian, Inc. Methods for multi-vessel renal neuromodulation
US10537734B2 (en) 2004-10-05 2020-01-21 Medtronic Ardian Luxembourg S.A.R.L. Methods and apparatus for multi-vessel renal neuromodulation
US9402992B2 (en) 2004-10-05 2016-08-02 Medtronic Ardian Luxembourg S.A.R.L. Methods and apparatus for multi-vessel renal neuromodulation
US9950161B2 (en) 2004-10-05 2018-04-24 Medtronic Ardian Luxembourg S.A.R.L. Methods and apparatus for multi-vessel renal neuromodulation
US8805545B2 (en) 2004-10-05 2014-08-12 Medtronic Ardian Luxembourg S.A.R.L. Methods and apparatus for multi-vessel renal neuromodulation
US9108040B2 (en) 2004-10-05 2015-08-18 Medtronic Ardian Luxembourg S.A.R.L. Methods and apparatus for multi-vessel renal neuromodulation
US9486355B2 (en) 2005-05-03 2016-11-08 Vessix Vascular, Inc. Selective accumulation of energy with or without knowledge of tissue topography
US11944376B2 (en) 2006-03-24 2024-04-02 Neuwave Medical, Inc. Transmission line with heat transfer ability
US10363092B2 (en) 2006-03-24 2019-07-30 Neuwave Medical, Inc. Transmission line with heat transfer ability
US9808300B2 (en) 2006-05-02 2017-11-07 Boston Scientific Scimed, Inc. Control of arterial smooth muscle tone
US11596474B2 (en) 2006-07-14 2023-03-07 Neuwave Medical, Inc. Energy delivery systems and uses thereof
US11576722B2 (en) 2006-07-14 2023-02-14 Neuwave Medical, Inc. Energy delivery systems and uses thereof
US11576723B2 (en) 2006-07-14 2023-02-14 Neuwave Medical, Inc. Energy delivery systems and uses thereof
US11389235B2 (en) 2006-07-14 2022-07-19 Neuwave Medical, Inc. Energy delivery systems and uses thereof
US10376314B2 (en) 2006-07-14 2019-08-13 Neuwave Medical, Inc. Energy delivery systems and uses thereof
US9974607B2 (en) 2006-10-18 2018-05-22 Vessix Vascular, Inc. Inducing desirable temperature effects on body tissue
US10413356B2 (en) 2006-10-18 2019-09-17 Boston Scientific Scimed, Inc. System for inducing desirable temperature effects on body tissue
US10213252B2 (en) 2006-10-18 2019-02-26 Vessix, Inc. Inducing desirable temperature effects on body tissue
US20090005771A1 (en) * 2007-06-28 2009-01-01 Chad Allen Lieber Optical Pyrometric Catheter for Tissue Temperature Monitoring During Cardiac Ablation
US7976537B2 (en) 2007-06-28 2011-07-12 Biosense Webster, Inc. Optical pyrometric catheter for tissue temperature monitoring during cardiac ablation
EP2008603A1 (en) * 2007-06-29 2008-12-31 Biosense Webster, Inc. Ablation catheter with optically transparent electricity conductive tip
US20090005773A1 (en) * 2007-06-29 2009-01-01 Christopher Beeckler Ablation catheter with optically transparent, electrically conductive tip
US8123745B2 (en) * 2007-06-29 2012-02-28 Biosense Webster, Inc. Ablation catheter with optically transparent, electrically conductive tip
US20090082762A1 (en) * 2007-09-20 2009-03-26 Ormsby Theodore C Radio frequency energy transmission device for the ablation of biological tissues
US20140025058A1 (en) * 2007-12-21 2014-01-23 Matthew J. Winkler Ablation device with internally cooled electrodes
US8915878B2 (en) * 2007-12-21 2014-12-23 Atricure, Inc. Ablation device with internally cooled electrodes
US8353907B2 (en) * 2007-12-21 2013-01-15 Atricure, Inc. Ablation device with internally cooled electrodes
US8118809B2 (en) * 2007-12-21 2012-02-21 St. Jude Medical, Atrial Fibrillation Division, Inc. Flexible conductive polymer electrode and method for ablation
US20090163905A1 (en) * 2007-12-21 2009-06-25 Winkler Matthew J Ablation device with internally cooled electrodes
WO2009082635A1 (en) * 2007-12-21 2009-07-02 St. Jude Medical, Atrial Fibrillation Division, Inc. Flexible conductive polymer electrode and method for ablation
US20090163916A1 (en) * 2007-12-21 2009-06-25 Saurav Paul Flexible Conductive Polymer Electrode and Method for Ablation
US8175679B2 (en) * 2007-12-26 2012-05-08 St. Jude Medical, Atrial Fibrillation Division, Inc. Catheter electrode that can simultaneously emit electrical energy and facilitate visualization by magnetic resonance imaging
US20120226143A1 (en) * 2007-12-26 2012-09-06 Gerhart John P Catheter electrode that can simultaneously emit electrical energy and facilitate visualization by magnetic resonance imaging
US8473029B2 (en) * 2007-12-26 2013-06-25 St. Jude Medical, Atrial Fibrillation Division, Inc. Catheter electrode that can simultaneously emit electrical energy and facilitate visualization by magnetic resonance imaging
US20090171187A1 (en) * 2007-12-26 2009-07-02 Gerhart John P Catheter electrode that can simultaneously emit electrical energy and facilitate visualization by magnetic resonance imaging
US20090171188A1 (en) * 2007-12-28 2009-07-02 Saurav Paul Flexible polymer electrode for mri-guided positioning and radio frequency ablation
US11331136B2 (en) 2007-12-28 2022-05-17 St. Jude Medical, Atrial Fibrillation Division, Inc. Flexible polymer electrode for MRI-guided positioning and radio frequency ablation
US9675410B2 (en) * 2007-12-28 2017-06-13 St. Jude Medical, Atrial Fibrillation Division, Inc. Flexible polymer electrode for MRI-guided positioning and radio frequency ablation
US20090299360A1 (en) * 2008-05-28 2009-12-03 Medwaves, Inc. Tissue ablation apparatus and method using ultrasonic imaging
US8133222B2 (en) 2008-05-28 2012-03-13 Medwaves, Inc. Tissue ablation apparatus and method using ultrasonic imaging
US8679106B2 (en) * 2008-07-01 2014-03-25 Medwaves, Inc. Angioplasty and tissue ablation apparatus and method
US20100004650A1 (en) * 2008-07-01 2010-01-07 Medwaves, Inc. Angioplasty and tissue ablation apparatus and method
EP2349452A1 (en) * 2008-10-21 2011-08-03 Microcube, LLC Microwave treatment devices and methods
US12011220B2 (en) * 2008-10-21 2024-06-18 Microcube, Llc Microwave treatment devices and methods
US11219484B2 (en) 2008-10-21 2022-01-11 Microcube, Llc Methods and devices for delivering microwave energy
US8968287B2 (en) 2008-10-21 2015-03-03 Microcube, Llc Methods and devices for applying energy to bodily tissues
US20220249163A1 (en) * 2008-10-21 2022-08-11 Microcube, Llc Microwave treatment devices and methods
US11291503B2 (en) * 2008-10-21 2022-04-05 Microcube, Llc Microwave treatment devices and methods
US10869720B2 (en) 2008-10-21 2020-12-22 Microcube, Llc Methods and devices for applying energy to bodily tissues
US10299859B2 (en) 2008-10-21 2019-05-28 Microcube, Llc Methods and devices for delivering microwave energy
US20100137857A1 (en) * 2008-10-21 2010-06-03 Microcube, Limited Liability Corporation Methods and devices for applying energy to bodily tissues
US9980774B2 (en) 2008-10-21 2018-05-29 Microcube, Llc Methods and devices for delivering microwave energy
US8808281B2 (en) * 2008-10-21 2014-08-19 Microcube, Llc Microwave treatment devices and methods
US9615882B2 (en) 2008-10-21 2017-04-11 Microcube, Llc Methods and devices for applying energy to bodily tissues
US11684418B2 (en) 2008-10-21 2023-06-27 Microcube, Llc Methods and devices for applying energy to bodily tissues
US20110004205A1 (en) * 2008-10-21 2011-01-06 Chu Chun Yiu Methods and devices for delivering microwave energy
EP2349452A4 (en) * 2008-10-21 2012-09-05 Microcube Llc METHOD AND DEVICES FOR MICROWAVE TREATMENT
US20100125269A1 (en) * 2008-10-21 2010-05-20 Microcube, Limited Liability Corporation Microwave treatment devices and methods
US10470819B2 (en) 2008-11-10 2019-11-12 Microcube, Llc Methods and devices for applying energy to bodily tissues
US20100121319A1 (en) * 2008-11-10 2010-05-13 Microcube, Llc Methods and devices for applying energy to bodily tissues
US11147619B2 (en) 2008-11-10 2021-10-19 Microcube, Llc Methods and devices for applying energy to bodily tissues
US9993293B2 (en) 2008-11-10 2018-06-12 Microcube, Llc Methods and devices for applying energy to bodily tissues
US9327100B2 (en) 2008-11-14 2016-05-03 Vessix Vascular, Inc. Selective drug delivery in a lumen
US20110060324A1 (en) * 2008-12-31 2011-03-10 Ardian, Inc. Apparatus, systems, and methods for achieving intravascular, thermally-induced renal neuromodulation
US20100168739A1 (en) * 2008-12-31 2010-07-01 Ardian, Inc. Apparatus, systems, and methods for achieving intravascular, thermally-induced renal neuromodulation
US8777942B2 (en) 2008-12-31 2014-07-15 Medtronic Ardian Luxembourg S.A.R.L. Apparatus, systems, and methods for achieving intravascular, thermally-induced renal neuromodulation
CN102438690A (zh) * 2008-12-31 2012-05-02 美敦力阿迪安有限公司 用于实现血管内热诱导肾神经调节的设备、系统以及方法
AU2009333040B2 (en) * 2008-12-31 2014-08-21 Medtronic Af Luxembourg S.A.R.L. Apparatus, systems and methods for achieving intravascular, thermally-induced renal neuromodulation
US10561460B2 (en) 2008-12-31 2020-02-18 Medtronic Ardian Luxembourg S.A.R.L. Neuromodulation systems and methods for treatment of sexual dysfunction
WO2010078175A1 (en) * 2008-12-31 2010-07-08 Ardian, Inc. Apparatus, systems and methods for achieving intravascular, thermally-induced renal neuromodulation
US8652129B2 (en) 2008-12-31 2014-02-18 Medtronic Ardian Luxembourg S.A.R.L. Apparatus, systems, and methods for achieving intravascular, thermally-induced renal neuromodulation
US10537385B2 (en) 2008-12-31 2020-01-21 Medtronic Ardian Luxembourg S.A.R.L. Intravascular, thermally-induced renal neuromodulation for treatment of polycystic ovary syndrome or infertility
US20100168731A1 (en) * 2008-12-31 2010-07-01 Ardian, Inc. Apparatus, systems, and methods for achieving intravascular, thermally-induced renal neuromodulation
US8974445B2 (en) 2009-01-09 2015-03-10 Recor Medical, Inc. Methods and apparatus for treatment of cardiac valve insufficiency
WO2010121047A2 (en) 2009-04-15 2010-10-21 Medwaves, Inc. Radio frequency based ablation system and method with dielectric transformer
EP2419040A2 (en) * 2009-04-15 2012-02-22 Medwaves, Inc. Radio frequency based ablation system and method with dielectric transformer
EP2419040A4 (en) * 2009-04-15 2013-01-23 Medwaves Inc RADIO FREQUENCY ABLATION SYSTEM AND METHOD USING A DIELECTRIC TRANSFORMER
US20100268219A1 (en) * 2009-04-15 2010-10-21 Medwaves, Inc. Radio frequency based ablation system and method with dielectric transformer
US8934989B2 (en) 2009-04-15 2015-01-13 Medwaves, Inc. Radio frequency based ablation system and method with dielectric transformer
US9277961B2 (en) 2009-06-12 2016-03-08 Advanced Cardiac Therapeutics, Inc. Systems and methods of radiometrically determining a hot-spot temperature of tissue being treated
US10357312B2 (en) 2009-07-28 2019-07-23 Neuwave Medical, Inc. Energy delivery systems and uses thereof
US9566115B2 (en) 2009-07-28 2017-02-14 Neuwave Medical, Inc. Energy delivery systems and uses thereof
US9877783B2 (en) 2009-07-28 2018-01-30 Neuwave Medical, Inc. Energy delivery systems and uses thereof
US11013557B2 (en) 2009-07-28 2021-05-25 Neuwave Medical, Inc. Energy delivery systems and uses thereof
US9039698B2 (en) * 2009-11-30 2015-05-26 Medwaves, Inc. Radio frequency ablation system with tracking sensor
US20110130750A1 (en) * 2009-11-30 2011-06-02 Medwaves, Inc. Radio frequency ablation system with tracking sensor
US9277955B2 (en) 2010-04-09 2016-03-08 Vessix Vascular, Inc. Power generating and control apparatus for the treatment of tissue
US9192790B2 (en) 2010-04-14 2015-11-24 Boston Scientific Scimed, Inc. Focused ultrasonic renal denervation
US8728075B2 (en) 2010-04-26 2014-05-20 Medtronic Ardian Luxembourg S.A.R.L. Multi-directional deflectable catheter apparatuses, systems, and methods for renal neuromodulation
US8870863B2 (en) 2010-04-26 2014-10-28 Medtronic Ardian Luxembourg S.A.R.L. Catheter apparatuses, systems, and methods for renal neuromodulation
US11490960B2 (en) 2010-05-03 2022-11-08 Neuwave Medical, Inc. Energy delivery systems and uses thereof
US9861440B2 (en) 2010-05-03 2018-01-09 Neuwave Medical, Inc. Energy delivery systems and uses thereof
US10603106B2 (en) 2010-05-03 2020-03-31 Neuwave Medical, Inc. Energy delivery systems and uses thereof
US10524862B2 (en) 2010-05-03 2020-01-07 Neuwave Medical, Inc. Energy delivery systems and uses thereof
US9872729B2 (en) 2010-05-03 2018-01-23 Neuwave Medical, Inc. Energy delivery systems and uses thereof
US10799263B2 (en) * 2010-05-07 2020-10-13 Carefusion 2200, Inc. Catheter design for use in treating pleural diseases
US20130204279A1 (en) * 2010-05-07 2013-08-08 Carefusion 2200, Inc. Catheter design for use in treating pleural diseases
US8880185B2 (en) 2010-06-11 2014-11-04 Boston Scientific Scimed, Inc. Renal denervation and stimulation employing wireless vascular energy transfer arrangement
US9408661B2 (en) 2010-07-30 2016-08-09 Patrick A. Haverkost RF electrodes on multiple flexible wires for renal nerve ablation
US9358365B2 (en) 2010-07-30 2016-06-07 Boston Scientific Scimed, Inc. Precision electrode movement control for renal nerve ablation
US9155589B2 (en) 2010-07-30 2015-10-13 Boston Scientific Scimed, Inc. Sequential activation RF electrode set for renal nerve ablation
US9463062B2 (en) 2010-07-30 2016-10-11 Boston Scientific Scimed, Inc. Cooled conductive balloon RF catheter for renal nerve ablation
US9084609B2 (en) 2010-07-30 2015-07-21 Boston Scientific Scime, Inc. Spiral balloon catheter for renal nerve ablation
US10179020B2 (en) 2010-10-25 2019-01-15 Medtronic Ardian Luxembourg S.A.R.L. Devices, systems and methods for evaluation and feedback of neuromodulation treatment
US8974451B2 (en) 2010-10-25 2015-03-10 Boston Scientific Scimed, Inc. Renal nerve ablation using conductive fluid jet and RF energy
US9220558B2 (en) 2010-10-27 2015-12-29 Boston Scientific Scimed, Inc. RF renal denervation catheter with multiple independent electrodes
US9848946B2 (en) 2010-11-15 2017-12-26 Boston Scientific Scimed, Inc. Self-expanding cooling electrode for renal nerve ablation
US9028485B2 (en) 2010-11-15 2015-05-12 Boston Scientific Scimed, Inc. Self-expanding cooling electrode for renal nerve ablation
US9089350B2 (en) 2010-11-16 2015-07-28 Boston Scientific Scimed, Inc. Renal denervation catheter with RF electrode and integral contrast dye injection arrangement
US9668811B2 (en) 2010-11-16 2017-06-06 Boston Scientific Scimed, Inc. Minimally invasive access for renal nerve ablation
US9326751B2 (en) 2010-11-17 2016-05-03 Boston Scientific Scimed, Inc. Catheter guidance of external energy for renal denervation
US9060761B2 (en) 2010-11-18 2015-06-23 Boston Scientific Scime, Inc. Catheter-focused magnetic field induced renal nerve ablation
US9023034B2 (en) 2010-11-22 2015-05-05 Boston Scientific Scimed, Inc. Renal ablation electrode with force-activatable conduction apparatus
US9192435B2 (en) 2010-11-22 2015-11-24 Boston Scientific Scimed, Inc. Renal denervation catheter with cooled RF electrode
US9649156B2 (en) 2010-12-15 2017-05-16 Boston Scientific Scimed, Inc. Bipolar off-wall electrode device for renal nerve ablation
US20140012077A1 (en) * 2011-01-11 2014-01-09 Quanta System S.P.A. Laser surgery device
US9220561B2 (en) 2011-01-19 2015-12-29 Boston Scientific Scimed, Inc. Guide-compatible large-electrode catheter for renal nerve ablation with reduced arterial injury
US9579030B2 (en) 2011-07-20 2017-02-28 Boston Scientific Scimed, Inc. Percutaneous devices and methods to visualize, target and ablate nerves
US9186209B2 (en) 2011-07-22 2015-11-17 Boston Scientific Scimed, Inc. Nerve modulation system having helical guide
US9186210B2 (en) 2011-10-10 2015-11-17 Boston Scientific Scimed, Inc. Medical devices including ablation electrodes
US10085799B2 (en) 2011-10-11 2018-10-02 Boston Scientific Scimed, Inc. Off-wall electrode device and methods for nerve modulation
US9420955B2 (en) 2011-10-11 2016-08-23 Boston Scientific Scimed, Inc. Intravascular temperature monitoring system and method
US9364284B2 (en) 2011-10-12 2016-06-14 Boston Scientific Scimed, Inc. Method of making an off-wall spacer cage
US9162046B2 (en) 2011-10-18 2015-10-20 Boston Scientific Scimed, Inc. Deflectable medical devices
US9079000B2 (en) 2011-10-18 2015-07-14 Boston Scientific Scimed, Inc. Integrated crossing balloon catheter
US8951251B2 (en) 2011-11-08 2015-02-10 Boston Scientific Scimed, Inc. Ostial renal nerve ablation
US9119600B2 (en) 2011-11-15 2015-09-01 Boston Scientific Scimed, Inc. Device and methods for renal nerve modulation monitoring
US9119632B2 (en) 2011-11-21 2015-09-01 Boston Scientific Scimed, Inc. Deflectable renal nerve ablation catheter
US10667860B2 (en) 2011-12-21 2020-06-02 Neuwave Medical, Inc. Energy delivery systems and uses thereof
US9265969B2 (en) 2011-12-21 2016-02-23 Cardiac Pacemakers, Inc. Methods for modulating cell function
US11638607B2 (en) 2011-12-21 2023-05-02 Neuwave Medical, Inc. Energy delivery systems and uses thereof
US9072902B2 (en) 2011-12-23 2015-07-07 Vessix Vascular, Inc. Methods and apparatuses for remodeling tissue of or adjacent to a body passage
US9028472B2 (en) 2011-12-23 2015-05-12 Vessix Vascular, Inc. Methods and apparatuses for remodeling tissue of or adjacent to a body passage
US9402684B2 (en) 2011-12-23 2016-08-02 Boston Scientific Scimed, Inc. Methods and apparatuses for remodeling tissue of or adjacent to a body passage
US9037259B2 (en) 2011-12-23 2015-05-19 Vessix Vascular, Inc. Methods and apparatuses for remodeling tissue of or adjacent to a body passage
US9186211B2 (en) 2011-12-23 2015-11-17 Boston Scientific Scimed, Inc. Methods and apparatuses for remodeling tissue of or adjacent to a body passage
US9174050B2 (en) 2011-12-23 2015-11-03 Vessix Vascular, Inc. Methods and apparatuses for remodeling tissue of or adjacent to a body passage
US9592386B2 (en) 2011-12-23 2017-03-14 Vessix Vascular, Inc. Methods and apparatuses for remodeling tissue of or adjacent to a body passage
US9433760B2 (en) 2011-12-28 2016-09-06 Boston Scientific Scimed, Inc. Device and methods for nerve modulation using a novel ablation catheter with polymeric ablative elements
US9050106B2 (en) 2011-12-29 2015-06-09 Boston Scientific Scimed, Inc. Off-wall electrode device and methods for nerve modulation
US10905494B2 (en) 2011-12-29 2021-02-02 St. Jude Medical, Atrial Fibrillation Division, Inc Flexible conductive polymer based conformable device and method to create linear endocardial lesions
US8926605B2 (en) 2012-02-07 2015-01-06 Advanced Cardiac Therapeutics, Inc. Systems and methods for radiometrically measuring temperature during tissue ablation
US8932284B2 (en) 2012-02-07 2015-01-13 Advanced Cardiac Therapeutics, Inc. Methods of determining tissue temperatures in energy delivery procedures
WO2013119620A1 (en) * 2012-02-07 2013-08-15 Advanced Cardiac Therapeutics, Inc. Systems and methods for radiometrically measuring temperature during tissue ablation
US11338140B2 (en) 2012-03-08 2022-05-24 Medtronic Ardian Luxembourg S.A.R.L. Monitoring of neuromodulation using biomarkers
US10874455B2 (en) 2012-03-08 2020-12-29 Medtronic Ardian Luxembourg S.A.R.L. Ovarian neuromodulation and associated systems and methods
US9226791B2 (en) 2012-03-12 2016-01-05 Advanced Cardiac Therapeutics, Inc. Systems for temperature-controlled ablation using radiometric feedback
US8961506B2 (en) 2012-03-12 2015-02-24 Advanced Cardiac Therapeutics, Inc. Methods of automatically regulating operation of ablation members based on determined temperatures
US10660703B2 (en) 2012-05-08 2020-05-26 Boston Scientific Scimed, Inc. Renal nerve modulation devices
US9014814B2 (en) 2012-06-01 2015-04-21 Advanced Cardiac Therapeutics, Inc. Methods of determining tissue contact based on radiometric signals
US8954161B2 (en) 2012-06-01 2015-02-10 Advanced Cardiac Therapeutics, Inc. Systems and methods for radiometrically measuring temperature and detecting tissue contact prior to and during tissue ablation
US11426573B2 (en) 2012-08-09 2022-08-30 University Of Iowa Research Foundation Catheters, catheter systems, and methods for puncturing through a tissue structure and ablating a tissue region
US10321946B2 (en) 2012-08-24 2019-06-18 Boston Scientific Scimed, Inc. Renal nerve modulation devices with weeping RF ablation balloons
US9173696B2 (en) 2012-09-17 2015-11-03 Boston Scientific Scimed, Inc. Self-positioning electrode system and method for renal nerve modulation
US10549127B2 (en) 2012-09-21 2020-02-04 Boston Scientific Scimed, Inc. Self-cooling ultrasound ablation catheter
US10398464B2 (en) 2012-09-21 2019-09-03 Boston Scientific Scimed, Inc. System for nerve modulation and innocuous thermal gradient nerve block
US10835305B2 (en) 2012-10-10 2020-11-17 Boston Scientific Scimed, Inc. Renal nerve modulation devices and methods
US10080864B2 (en) 2012-10-19 2018-09-25 Medtronic Ardian Luxembourg S.A.R.L. Packaging for catheter treatment devices and associated devices, systems, and methods
US9693821B2 (en) 2013-03-11 2017-07-04 Boston Scientific Scimed, Inc. Medical devices for modulating nerves
US9956033B2 (en) 2013-03-11 2018-05-01 Boston Scientific Scimed, Inc. Medical devices for modulating nerves
US9808311B2 (en) 2013-03-13 2017-11-07 Boston Scientific Scimed, Inc. Deflectable medical devices
US9297845B2 (en) 2013-03-15 2016-03-29 Boston Scientific Scimed, Inc. Medical devices and methods for treatment of hypertension that utilize impedance compensation
US10265122B2 (en) 2013-03-15 2019-04-23 Boston Scientific Scimed, Inc. Nerve ablation devices and related methods of use
US9827039B2 (en) 2013-03-15 2017-11-28 Boston Scientific Scimed, Inc. Methods and apparatuses for remodeling tissue of or adjacent to a body passage
US10022182B2 (en) 2013-06-21 2018-07-17 Boston Scientific Scimed, Inc. Medical devices for renal nerve ablation having rotatable shafts
US9943365B2 (en) 2013-06-21 2018-04-17 Boston Scientific Scimed, Inc. Renal denervation balloon catheter with ride along electrode support
US9707036B2 (en) 2013-06-25 2017-07-18 Boston Scientific Scimed, Inc. Devices and methods for nerve modulation using localized indifferent electrodes
US9833283B2 (en) 2013-07-01 2017-12-05 Boston Scientific Scimed, Inc. Medical devices for renal nerve ablation
US10413357B2 (en) 2013-07-11 2019-09-17 Boston Scientific Scimed, Inc. Medical device with stretchable electrode assemblies
US10660698B2 (en) 2013-07-11 2020-05-26 Boston Scientific Scimed, Inc. Devices and methods for nerve modulation
US9925001B2 (en) 2013-07-19 2018-03-27 Boston Scientific Scimed, Inc. Spiral bipolar electrode renal denervation balloon
US10695124B2 (en) 2013-07-22 2020-06-30 Boston Scientific Scimed, Inc. Renal nerve ablation catheter having twist balloon
US10342609B2 (en) 2013-07-22 2019-07-09 Boston Scientific Scimed, Inc. Medical devices for renal nerve ablation
US10722300B2 (en) 2013-08-22 2020-07-28 Boston Scientific Scimed, Inc. Flexible circuit having improved adhesion to a renal nerve modulation balloon
US9895194B2 (en) 2013-09-04 2018-02-20 Boston Scientific Scimed, Inc. Radio frequency (RF) balloon catheter having flushing and cooling capability
US10952790B2 (en) 2013-09-13 2021-03-23 Boston Scientific Scimed, Inc. Ablation balloon with vapor deposited cover layer
WO2015042173A1 (en) * 2013-09-20 2015-03-26 Advanced Cardiac Therapeutics, Inc. Temperature sensing and tissue ablation using a plurality of electrodes
US9687166B2 (en) 2013-10-14 2017-06-27 Boston Scientific Scimed, Inc. High resolution cardiac mapping electrode array catheter
US11246654B2 (en) 2013-10-14 2022-02-15 Boston Scientific Scimed, Inc. Flexible renal nerve ablation devices and related methods of use and manufacture
US9962223B2 (en) 2013-10-15 2018-05-08 Boston Scientific Scimed, Inc. Medical device balloon
US9770606B2 (en) 2013-10-15 2017-09-26 Boston Scientific Scimed, Inc. Ultrasound ablation catheter with cooling infusion and centering basket
US10945786B2 (en) 2013-10-18 2021-03-16 Boston Scientific Scimed, Inc. Balloon catheters with flexible conducting wires and related methods of use and manufacture
US10271898B2 (en) 2013-10-25 2019-04-30 Boston Scientific Scimed, Inc. Embedded thermocouple in denervation flex circuit
US20160310211A1 (en) * 2014-01-06 2016-10-27 Iowa Approach Inc. Apparatus and methods for renal denervation ablation
US11589919B2 (en) 2014-01-06 2023-02-28 Boston Scientific Scimed, Inc. Apparatus and methods for renal denervation ablation
US10517672B2 (en) * 2014-01-06 2019-12-31 Farapulse, Inc. Apparatus and methods for renal denervation ablation
US11202671B2 (en) 2014-01-06 2021-12-21 Boston Scientific Scimed, Inc. Tear resistant flex circuit assembly
US9907609B2 (en) 2014-02-04 2018-03-06 Boston Scientific Scimed, Inc. Alternative placement of thermal sensors on bipolar electrode
US11000679B2 (en) 2014-02-04 2021-05-11 Boston Scientific Scimed, Inc. Balloon protection and rewrapping devices and related methods of use
US10194979B1 (en) 2014-03-28 2019-02-05 Medtronic Ardian Luxembourg S.A.R.L. Methods for catheter-based renal neuromodulation
US9980766B1 (en) 2014-03-28 2018-05-29 Medtronic Ardian Luxembourg S.A.R.L. Methods and systems for renal neuromodulation
US10194980B1 (en) 2014-03-28 2019-02-05 Medtronic Ardian Luxembourg S.A.R.L. Methods for catheter-based renal neuromodulation
US11259869B2 (en) 2014-05-07 2022-03-01 Farapulse, Inc. Methods and apparatus for selective tissue ablation
US10433906B2 (en) 2014-06-12 2019-10-08 Farapulse, Inc. Method and apparatus for rapid and selective transurethral tissue ablation
US10624693B2 (en) 2014-06-12 2020-04-21 Farapulse, Inc. Method and apparatus for rapid and selective tissue ablation with cooling
US11241282B2 (en) 2014-06-12 2022-02-08 Boston Scientific Scimed, Inc. Method and apparatus for rapid and selective transurethral tissue ablation
US11622803B2 (en) 2014-06-12 2023-04-11 Boston Scientific Scimed, Inc. Method and apparatus for rapid and selective tissue ablation with cooling
US9999465B2 (en) 2014-10-14 2018-06-19 Iowa Approach, Inc. Method and apparatus for rapid and safe pulmonary vein cardiac ablation
US10835314B2 (en) 2014-10-14 2020-11-17 Farapulse, Inc. Method and apparatus for rapid and safe pulmonary vein cardiac ablation
US9522036B2 (en) 2014-11-19 2016-12-20 Advanced Cardiac Therapeutics, Inc. Ablation devices, systems and methods of using a high-resolution electrode assembly
US10499983B2 (en) 2014-11-19 2019-12-10 Epix Therapeutics, Inc. Ablation systems and methods using heat shunt networks
US10166062B2 (en) 2014-11-19 2019-01-01 Epix Therapeutics, Inc. High-resolution mapping of tissue with pacing
US9592092B2 (en) 2014-11-19 2017-03-14 Advanced Cardiac Therapeutics, Inc. Orientation determination based on temperature measurements
US9522037B2 (en) 2014-11-19 2016-12-20 Advanced Cardiac Therapeutics, Inc. Treatment adjustment based on temperatures from multiple temperature sensors
US9510905B2 (en) 2014-11-19 2016-12-06 Advanced Cardiac Therapeutics, Inc. Systems and methods for high-resolution mapping of tissue
US11642167B2 (en) 2014-11-19 2023-05-09 Epix Therapeutics, Inc. Electrode assembly with thermal shunt member
US9517103B2 (en) 2014-11-19 2016-12-13 Advanced Cardiac Therapeutics, Inc. Medical instruments with multiple temperature sensors
US11534227B2 (en) 2014-11-19 2022-12-27 Epix Therapeutics, Inc. High-resolution mapping of tissue with pacing
US11701171B2 (en) 2014-11-19 2023-07-18 Epix Therapeutics, Inc. Methods of removing heat from an electrode using thermal shunting
US11135009B2 (en) 2014-11-19 2021-10-05 Epix Therapeutics, Inc. Electrode assembly with thermal shunt member
US10660701B2 (en) 2014-11-19 2020-05-26 Epix Therapeutics, Inc. Methods of removing heat from an electrode using thermal shunting
US10413212B2 (en) 2014-11-19 2019-09-17 Epix Therapeutics, Inc. Methods and systems for enhanced mapping of tissue
US10231779B2 (en) 2014-11-19 2019-03-19 Epix Therapeutics, Inc. Ablation catheter with high-resolution electrode assembly
US10383686B2 (en) 2014-11-19 2019-08-20 Epix Therapeutics, Inc. Ablation systems with multiple temperature sensors
US9636164B2 (en) 2015-03-25 2017-05-02 Advanced Cardiac Therapeutics, Inc. Contact sensing systems and methods
US11576714B2 (en) 2015-03-25 2023-02-14 Epix Therapeutics, Inc. Contact sensing systems and methods
US10675081B2 (en) 2015-03-25 2020-06-09 Epix Therapeutics, Inc. Contact sensing systems and methods
US11678935B2 (en) 2015-10-26 2023-06-20 Neuwave Medical, Inc. Energy delivery systems and uses thereof
US10952792B2 (en) 2015-10-26 2021-03-23 Neuwave Medical, Inc. Energy delivery systems and uses thereof
US11589921B2 (en) 2016-01-05 2023-02-28 Boston Scientific Scimed, Inc. Systems, apparatuses and methods for delivery of ablative energy to tissue
US10660702B2 (en) 2016-01-05 2020-05-26 Farapulse, Inc. Systems, devices, and methods for focal ablation
US10172673B2 (en) 2016-01-05 2019-01-08 Farapulse, Inc. Systems devices, and methods for delivery of pulsed electric field ablative energy to endocardial tissue
US10433908B2 (en) 2016-01-05 2019-10-08 Farapulse, Inc. Systems, devices, and methods for delivery of pulsed electric field ablative energy to endocardial tissue
US10512779B2 (en) 2016-01-05 2019-12-24 Farapulse, Inc. Systems, apparatuses and methods for delivery of ablative energy to tissue
US10709891B2 (en) 2016-01-05 2020-07-14 Farapulse, Inc. Systems, apparatuses and methods for delivery of ablative energy to tissue
US10322286B2 (en) 2016-01-05 2019-06-18 Farapulse, Inc. Systems, apparatuses and methods for delivery of ablative energy to tissue
US11020179B2 (en) 2016-01-05 2021-06-01 Farapulse, Inc. Systems, devices, and methods for focal ablation
US10842561B2 (en) 2016-01-05 2020-11-24 Farapulse, Inc. Systems, devices, and methods for delivery of pulsed electric field ablative energy to endocardial tissue
US9993178B2 (en) 2016-03-15 2018-06-12 Epix Therapeutics, Inc. Methods of determining catheter orientation
US11389230B2 (en) 2016-03-15 2022-07-19 Epix Therapeutics, Inc. Systems for determining catheter orientation
US12121291B2 (en) 2016-03-15 2024-10-22 Epix Therapeutics, Inc. Methods of determining catheter orientation
US11179197B2 (en) 2016-03-15 2021-11-23 Epix Therapeutics, Inc. Methods of determining catheter orientation
US10531917B2 (en) 2016-04-15 2020-01-14 Neuwave Medical, Inc. Systems and methods for energy delivery
US11395699B2 (en) 2016-04-15 2022-07-26 Neuwave Medical, Inc. Systems and methods for energy delivery
US10507302B2 (en) 2016-06-16 2019-12-17 Farapulse, Inc. Systems, apparatuses, and methods for guide wire delivery
US20180008345A1 (en) * 2016-07-11 2018-01-11 Gyrus Medical Limited System and method for monitoring a microwave tissue ablation process
US20180008346A1 (en) * 2016-07-11 2018-01-11 Gyrus Medical Limited System and method for monitoring tissue temperature
US11090114B2 (en) * 2016-07-11 2021-08-17 Gyrus Medical Limited System and method for monitoring tissue temperature
US11076915B2 (en) * 2016-07-11 2021-08-03 Gyrus Medical Limited System and method for monitoring a microwave tissue ablation process
US20210106381A1 (en) * 2017-04-03 2021-04-15 Broncus Medical Inc. Electrosurgical access sheath
US11832877B2 (en) * 2017-04-03 2023-12-05 Broncus Medical Inc. Electrosurgical access sheath
WO2018187244A3 (en) * 2017-04-03 2019-03-07 Broncus Medical Inc. ELECTROSURGICAL ACCESS SLEEVE
US10888373B2 (en) 2017-04-27 2021-01-12 Epix Therapeutics, Inc. Contact assessment between an ablation catheter and tissue
US10893903B2 (en) 2017-04-27 2021-01-19 Epix Therapeutics, Inc. Medical instruments having contact assessment features
US12121720B2 (en) 2017-04-27 2024-10-22 Boston Scientific Scimed, Inc. Systems, devices, and methods for signal generation
US10016232B1 (en) 2017-04-27 2018-07-10 Iowa Approach, Inc. Systems, devices, and methods for signal generation
US9987081B1 (en) 2017-04-27 2018-06-05 Iowa Approach, Inc. Systems, devices, and methods for signal generation
US11357978B2 (en) 2017-04-27 2022-06-14 Boston Scientific Scimed, Inc. Systems, devices, and methods for signal generation
US11617618B2 (en) 2017-04-27 2023-04-04 Epix Therapeutics, Inc. Contact assessment between an ablation catheter and tissue
US10617867B2 (en) 2017-04-28 2020-04-14 Farapulse, Inc. Systems, devices, and methods for delivery of pulsed electric field ablative energy to esophageal tissue
US11833350B2 (en) 2017-04-28 2023-12-05 Boston Scientific Scimed, Inc. Systems, devices, and methods for delivery of pulsed electric field ablative energy to esophageal tissue
US10617467B2 (en) 2017-07-06 2020-04-14 Farapulse, Inc. Systems, devices, and methods for focal ablation
US10130423B1 (en) 2017-07-06 2018-11-20 Farapulse, Inc. Systems, devices, and methods for focal ablation
US10893905B2 (en) 2017-09-12 2021-01-19 Farapulse, Inc. Systems, apparatuses, and methods for ventricular focal ablation
US11672596B2 (en) 2018-02-26 2023-06-13 Neuwave Medical, Inc. Energy delivery devices with flexible and adjustable tips
US12042208B2 (en) 2018-05-03 2024-07-23 Boston Scientific Scimed, Inc. Systems, devices, and methods for ablation using surgical clamps
US10512505B2 (en) 2018-05-07 2019-12-24 Farapulse, Inc. Systems, apparatuses and methods for delivery of ablative energy to tissue
US10709502B2 (en) 2018-05-07 2020-07-14 Farapulse, Inc. Systems, apparatuses and methods for delivery of ablative energy to tissue
US11020180B2 (en) 2018-05-07 2021-06-01 Farapulse, Inc. Epicardial ablation catheter
US11033236B2 (en) 2018-05-07 2021-06-15 Farapulse, Inc. Systems, apparatuses, and methods for filtering high voltage noise induced by pulsed electric field ablation
US20210196378A1 (en) * 2018-08-13 2021-07-01 The University Of Sydney Catheter ablation device with temperature monitoring
US10687892B2 (en) 2018-09-20 2020-06-23 Farapulse, Inc. Systems, apparatuses, and methods for delivery of pulsed electric field ablative energy to endocardial tissue
US11832879B2 (en) 2019-03-08 2023-12-05 Neuwave Medical, Inc. Systems and methods for energy delivery
US11738200B2 (en) 2019-09-17 2023-08-29 Boston Scientific Scimed, Inc. Systems, apparatuses, and methods for detecting ectopic electrocardiogram signals during pulsed electric field ablation
US10625080B1 (en) 2019-09-17 2020-04-21 Farapulse, Inc. Systems, apparatuses, and methods for detecting ectopic electrocardiogram signals during pulsed electric field ablation
US10688305B1 (en) 2019-09-17 2020-06-23 Farapulse, Inc. Systems, apparatuses, and methods for detecting ectopic electrocardiogram signals during pulsed electric field ablation
US11065047B2 (en) 2019-11-20 2021-07-20 Farapulse, Inc. Systems, apparatuses, and methods for protecting electronic components from high power noise induced by high voltage pulses
US11931090B2 (en) 2019-11-20 2024-03-19 Boston Scientific Scimed, Inc. Systems, apparatuses, and methods for protecting electronic components from high power noise induced by high voltage pulses
US11684408B2 (en) 2019-11-20 2023-06-27 Boston Scientific Scimed, Inc. Systems, apparatuses, and methods for protecting electronic components from high power noise induced by high voltage pulses
US11497541B2 (en) 2019-11-20 2022-11-15 Boston Scientific Scimed, Inc. Systems, apparatuses, and methods for protecting electronic components from high power noise induced by high voltage pulses
US10842572B1 (en) 2019-11-25 2020-11-24 Farapulse, Inc. Methods, systems, and apparatuses for tracking ablation devices and generating lesion lines

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EP2073738B1 (en) 2015-06-10
US20080015570A1 (en) 2008-01-17
US8308722B2 (en) 2012-11-13

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