US20040249399A1 - Device for assembling blood vessels - Google Patents
Device for assembling blood vessels Download PDFInfo
- Publication number
- US20040249399A1 US20040249399A1 US10/484,159 US48415904A US2004249399A1 US 20040249399 A1 US20040249399 A1 US 20040249399A1 US 48415904 A US48415904 A US 48415904A US 2004249399 A1 US2004249399 A1 US 2004249399A1
- Authority
- US
- United States
- Prior art keywords
- connector
- vessel
- external
- cylinder
- cylinders
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/04—Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
- A61F2/06—Blood vessels
- A61F2/064—Blood vessels with special features to facilitate anastomotic coupling
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/08—Muscles; Tendons; Ligaments
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/08—Muscles; Tendons; Ligaments
- A61F2002/0894—Muscles
Definitions
- the present invention relates to a device for jointing flexible ducts.
- the case of the jointing of two blood vessels will more specifically be considered herein, but, generally, each of the vessels may be any type of duct with a non-rigid flexible wall.
- the stump of a blood vessel, vein or artery is a fragile piece of flesh, uneasy to handle and, conventionally, it can only be connected to another vessel by means of a sewing.
- the present invention provides transforming the stump end into an object which is easy to handle and connect by equipping each stump with a connector connectable to a complementary connector.
- the present invention provides a vessel connector, comprising an internal cylinder insertable inside of a portion of the end of a vessel, and an external cylinder arranged at the external periphery of said end, one of the two cylinders being capable of expanding/compressing after its putting into place, whereby the vessel is blocked between the two cylinders after their putting into place.
- the internal cylinder is capable of expanding after its putting into place and the external cylinder is non-expandable, this external cylinder being provided with means of attachment to an external cylinder equipping another vessel.
- the external cylinder is formed of two half-cylinders associated with a temporary attachment means.
- the present invention also aims at a device for jointing vessels respectively equipped with a connector, in which each of the external cylinders comprises complementary male and female connection means.
- the first vessel is equipped with a male connector and the second vessel is equipped with a female connector, the external cylinder of which has a diameter greater than that of the external cylinder of the first connector and at least the end portion of which is flexible, this end portion being surrounded with two removable half-cylinders, themselves surrounded with a stent acting in compression.
- the vessel jointing device uses a connector in which the internal cylinder penetrates into two opposite vessels and the external cylinder surrounds the external periphery of the two vessels.
- FIG. 1 shows an end of a blood vessel equipped with a connector according to an embodiment of the present invention
- FIGS. 2A-2D illustrate a placing mode of the connector of FIG. 1;
- FIGS. 3A and 3B illustrate an example of application of the present invention to a blood vessel jointing operation
- FIGS. 4 to 7 illustrate various alternatives of devices according to the present invention.
- FIG. 8 illustrates another embodiment of the present invention.
- “stent” will be used to designate a hollow cylindrical object with full or open-worked walls made of a material capable of having at an initial state a first dimension (first internal and external diameters) and at a final state a second dimension (second internal and external diameters). It may be a cylinder, the internal and external diameters of which tend to increase or to decrease, or a cylinder, the internal diameter of which tends to decrease, or a cylinder, the external diameter of which tends to increase. In the case of a cylinder, the external diameter of which tends to increase, the stent will be likely to exert an expansion effort on the medium arranged at its external periphery. In the second case, the stent will be likely to exert a compressive effort on the medium located at its internal periphery.
- Such stents may use various physical phenomena. It may for example be shape-memory materials, devices of pneumatic type, or osmotic effect devices. In this last case, the stent will be formed of a cylinder with a double wall, containing an osmotic material so that the pressure between the two walls increases when the stent is plunged into a liquid, one or the other of the two walls being likely to deform.
- FIG. 1 is a perspective view of a blood vessel 1 provided with a connector according to the present invention.
- the connector comprises a stent 2 arranged inside of the vessel and a non-expandable cylinder 3 arranged outside of the vessel.
- the stent is such that, once placed inside of the vessel, it tends to increase its diameter so that vessel 1 is stuck between stent 2 and cylinder 3 .
- cylinder 3 intended to be used as a support will be called the “anvil”. It is preferably not a cylinder made of a rigid material, but a cylinder made of a non-extensible flexible material, for example, a biocompatible metal, fabric, or plastic cylinder.
- FIGS. 2A to 2 D illustrate successive steps of the putting into place of the connector of FIG. 1 at the end of a blood vessel 1 by means of an introducing device 5 .
- the introducer has the shape of a cylinder of small diameter. It may be introduced through a percutaneous orifice.
- the introducer end located outside of the patient will be called the “proximal end” and the introducer end located inside of the field of operation will be called the “distal end”.
- the introducer is comprised of a core 6 and of a sheath 7 mobile in translation with respect to each other.
- An element such as a stent 2 may be housed in the distal portion of the sheath.
- the stent then remains to be released.
- the stent introducers enable this functionality by means of devices located at the proximal end. This phase is critical, because the stent may slide with respect to the stump.
- a partially reversible introducing device will preferably be chosen. Such a device enables having the stent return into its protective sheath, provided that the stent has not completely come out of it (typically, the stent must be “spread out” over less than a set percentage, for example, 80%, of its length). It should be noted that the used stent tends to have a greater diameter than the vessel (due to this difference in diameters, the stent will be able to press the vessel wall against the anvil's).
- cylindrical anvil 3 is introduced from the proximal end. It is a hollow cylinder that can slide as far as the stump. A clip enables putting it in the right place. The stent release can then be complete by maneuvering the proximal end of the introducer. The stent releases all its centripetal radial compression force, thus pressing the vessel wall against the anvil (FIG. 2D).
- male and female connectors comprising stents 2 and 12 and anvils 3 and 13 .
- Female anvil 3 preferably has an end portion of reduced diameter.
- Male anvil 13 comprises an end portion made of a flexible, but non-extensible material.
- at least the end portion of anvil 13 is surrounded with two rigid half-cylinders 14 a, 14 b, each of which is equipped at one end with a catch (small gripping excrescence) 15 a, 15 b and with a stent 16 having a tendency to contracting (decreasing its diameter).
- Half-cylinders 14 a, 14 b are maintained in placed against each other under the effect of the pressure exerted by stent 16 .
- Two clips introduced into the operation field enable handling the two stumps equipped with connectors. As illustrated in FIG. 3B, the end of anvil 3 can thus be introduced into the end of anvil 13 . Clips are also used to successively grip catches 15 a and 15 b and remove rigid semi-cylinders 14 a and 14 b. The jointing is thus performed and maintained under the effect of the pressure exerted by stent 16 .
- cylinders 3 and 13 forming an anvil are provided at their ends with fast connection male and female devices 18 a and 18 b.
- Such devices such as, for example, threads, or “clipsing” devices, are very current to quickly connect pipes, in particular for those used in the medical field.
- two male or two female connectors and one complementary intermediary connection part may be used instead of specializing two specific male and female connectors at the end of two stumps to be connected.
- two male or two female connectors and one complementary intermediary connection part may be used.
- an intermediary T-shaped part to which are connected stumps equipped with connectors as described hereabove may be used.
- FIGS. 5 and 6 illustrate another embodiment of the present invention in which a single stent 22 is inserted into the two ends of two vessels 1 and 11 and these two ends are altogether surrounded at their external periphery with a non-extensible cylinder 23 .
- FIG. 5 shows the device while stent 22 is in its initial position, before expanding
- FIG. 6 shows the device while the stent is in expanded position.
- the stent is preferably of pneumatically- or osmotically-inflatable type.
- FIG. 7 shows another alternative of the present invention in which a single stent 22 is inserted into the two ends of the two assembled vessels 1 and 11 and two cylinders forming an anvil 25 and 26 are arranged at the external periphery of the vessel ends.
- FIG. 8 shows another embodiment of the present invention in which a first vessel 1 is associated with a male connector while a second vessel 11 is associated with a female connector.
- the male connector comprises an internal stent 2 and an external stent forming an anvil.
- the external cylinder is formed of two half-cylinders 31 a and 31 b respectively associated with grip catches 32 a and 32 b.
- Half-cylinders 31 a and 31 b are assembled in any selected fashion, for example, by a wire or net 33 that maintains them in place and enables them to temporarily be used as an anvil.
- the female connector is bell-mouthed and comprises two external half-cylinders 35 a and 35 b, respectively associated with gripping catches 36 a and 36 b.
- the blood vessel is everted and pressed against the bell mouth of the connector to which it is temporarily attached by clips, wires, or the like.
- the assembly is surrounded with a cylindrical stent 37 , the internal diameter of which tends to decrease.
- the assembly of the male and female connectors is performed by inserting the male connector into the female connector, by cutting wire or net 33 , and by successively removing half-cylinders 32 a, 32 b, then half-cylinders 36 a and 36 b after having detached them from vessel 11 . Then, the connection is ensured by the two stents 2 and 37 operating antagonistically, stent 2 exerting an expansion force and stent 37 a compression force.
- the external cylinder forming an anvil, may also be provided in the various embodiments to be a longitudinally split cylinder, the two opposite portions of the split being attachable to each other after being put into place, for example by fast connection.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR0109526A FR2827502B1 (fr) | 2001-07-17 | 2001-07-17 | Micromuscle en milieu biologique |
FR01/09526 | 2001-07-17 | ||
PCT/FR2002/002555 WO2003007843A2 (fr) | 2001-07-17 | 2002-07-17 | Dispositif d'anastomose vasculaire |
Publications (1)
Publication Number | Publication Date |
---|---|
US20040249399A1 true US20040249399A1 (en) | 2004-12-09 |
Family
ID=8865602
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US10/484,159 Abandoned US20040249399A1 (en) | 2001-07-17 | 2002-07-17 | Device for assembling blood vessels |
US10/484,062 Expired - Fee Related US7611887B2 (en) | 2001-07-17 | 2002-07-17 | Micro-muscle in biological medium |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US10/484,062 Expired - Fee Related US7611887B2 (en) | 2001-07-17 | 2002-07-17 | Micro-muscle in biological medium |
Country Status (7)
Country | Link |
---|---|
US (2) | US20040249399A1 (fr) |
EP (2) | EP1414371B1 (fr) |
JP (2) | JP2004534610A (fr) |
AU (1) | AU2002336139A1 (fr) |
DE (1) | DE60236937D1 (fr) |
FR (1) | FR2827502B1 (fr) |
WO (2) | WO2003007844A1 (fr) |
Cited By (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20050080482A1 (en) * | 2003-10-14 | 2005-04-14 | Craig Bonsignore | Graft coupling apparatus and methods of using same |
US20070179598A1 (en) * | 2006-02-01 | 2007-08-02 | Duerig Thomas W | Method and system of attaching vessels to grafts |
US20070246233A1 (en) * | 2006-04-04 | 2007-10-25 | Johnson A D | Thermal actuator for fire protection sprinkler head |
US7763342B2 (en) | 2005-03-31 | 2010-07-27 | Tini Alloy Company | Tear-resistant thin film methods of fabrication |
US7842143B2 (en) | 2007-12-03 | 2010-11-30 | Tini Alloy Company | Hyperelastic shape setting devices and fabrication methods |
US20110108602A1 (en) * | 2009-11-11 | 2011-05-12 | Biorep Technologies, Inc. | Anastomosis system and method |
US8007674B2 (en) | 2007-07-30 | 2011-08-30 | Tini Alloy Company | Method and devices for preventing restenosis in cardiovascular stents |
US8349099B1 (en) | 2006-12-01 | 2013-01-08 | Ormco Corporation | Method of alloying reactive components |
US8382917B2 (en) | 2007-12-03 | 2013-02-26 | Ormco Corporation | Hyperelastic shape setting devices and fabrication methods |
US8556969B2 (en) | 2007-11-30 | 2013-10-15 | Ormco Corporation | Biocompatible copper-based single-crystal shape memory alloys |
US8584767B2 (en) | 2007-01-25 | 2013-11-19 | Tini Alloy Company | Sprinkler valve with active actuation |
US8684101B2 (en) | 2007-01-25 | 2014-04-01 | Tini Alloy Company | Frangible shape memory alloy fire sprinkler valve actuator |
US20150005872A1 (en) * | 2011-05-12 | 2015-01-01 | Cook Medical Technologies Llc | Emergency vascular repair prosthesis |
WO2015192022A1 (fr) * | 2014-06-13 | 2015-12-17 | The Regents Of The University Of California | Dispositif d'anastomose sans suture |
US10124197B2 (en) | 2012-08-31 | 2018-11-13 | TiNi Allot Company | Fire sprinkler valve actuator |
US10765541B2 (en) | 2011-12-06 | 2020-09-08 | Aortic Innovations, Llc | Device for endovascular aortic repair and method of using the same |
US11040230B2 (en) | 2012-08-31 | 2021-06-22 | Tini Alloy Company | Fire sprinkler valve actuator |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL155305A0 (en) * | 2003-04-09 | 2003-11-23 | Giler Ltd | Stent for use in mammalian anastomosis and method and system for implanting said stent |
US8615289B2 (en) * | 2004-02-20 | 2013-12-24 | Koninklijke Philips N.V. | Drug application during a CT scan |
US20060149364A1 (en) * | 2004-12-31 | 2006-07-06 | Steven Walak | Low profile vascular graft |
US7452372B2 (en) * | 2005-09-22 | 2008-11-18 | Boston Scientific Scimed, Inc. | Bifurcated stent |
BRPI0708528A2 (pt) * | 2006-03-03 | 2011-05-31 | Vayro Ltd | dispositivo de fixação, stent, e, método para produzir um dispositivo de fixação, e para a conexão de um primeiro objeto a um segundo objeto |
WO2007124128A2 (fr) * | 2006-04-20 | 2007-11-01 | Liquidia Technologies, Inc. | Dispositifs biologiques de régularisation du débit sanguin et procédés associés |
US8105261B2 (en) * | 2007-07-02 | 2012-01-31 | Cardiac Pacemakers, Inc. | Osmotic devices and methods for diuretic therapy |
US8328828B2 (en) | 2008-08-11 | 2012-12-11 | Board Of Trustees Of The University Of Arkansas | Device for performing an anastomosis |
EP2299119B1 (fr) | 2009-09-22 | 2018-11-07 | ECP Entwicklungsgesellschaft mbH | Rotor gonflable pour une pompe à fluide |
KR101688735B1 (ko) * | 2015-06-22 | 2016-12-22 | 연세대학교 산학협력단 | 스텐트 구조물을 구비한 혈관 문합기 |
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- 2002-07-17 US US10/484,159 patent/US20040249399A1/en not_active Abandoned
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- 2002-07-17 EP EP02770034A patent/EP1414372A2/fr not_active Withdrawn
- 2002-07-17 AU AU2002336139A patent/AU2002336139A1/en not_active Abandoned
- 2002-07-17 US US10/484,062 patent/US7611887B2/en not_active Expired - Fee Related
- 2002-07-17 JP JP2003513452A patent/JP2004534610A/ja active Pending
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Cited By (30)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20050080482A1 (en) * | 2003-10-14 | 2005-04-14 | Craig Bonsignore | Graft coupling apparatus and methods of using same |
US7763342B2 (en) | 2005-03-31 | 2010-07-27 | Tini Alloy Company | Tear-resistant thin film methods of fabrication |
US20070179598A1 (en) * | 2006-02-01 | 2007-08-02 | Duerig Thomas W | Method and system of attaching vessels to grafts |
US20070246233A1 (en) * | 2006-04-04 | 2007-10-25 | Johnson A D | Thermal actuator for fire protection sprinkler head |
US10190199B2 (en) | 2006-12-01 | 2019-01-29 | Ormco Corporation | Method of alloying reactive components |
US9340858B2 (en) | 2006-12-01 | 2016-05-17 | Ormco Corporation | Method of alloying reactive components |
US8685183B1 (en) | 2006-12-01 | 2014-04-01 | Ormco Corporation | Method of alloying reactive components |
US8349099B1 (en) | 2006-12-01 | 2013-01-08 | Ormco Corporation | Method of alloying reactive components |
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Also Published As
Publication number | Publication date |
---|---|
EP1414371B1 (fr) | 2010-07-07 |
WO2003007843A2 (fr) | 2003-01-30 |
US20040248269A1 (en) | 2004-12-09 |
FR2827502B1 (fr) | 2004-04-09 |
JP2004534611A (ja) | 2004-11-18 |
EP1414371A1 (fr) | 2004-05-06 |
US7611887B2 (en) | 2009-11-03 |
EP1414372A2 (fr) | 2004-05-06 |
FR2827502A1 (fr) | 2003-01-24 |
JP2004534610A (ja) | 2004-11-18 |
WO2003007843A3 (fr) | 2003-05-15 |
AU2002336139A1 (en) | 2003-03-03 |
JP4276939B2 (ja) | 2009-06-10 |
DE60236937D1 (de) | 2010-08-19 |
WO2003007844A1 (fr) | 2003-01-30 |
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