US20030199753A1 - MRI compatible biopsy device with detachable probe - Google Patents
MRI compatible biopsy device with detachable probe Download PDFInfo
- Publication number
- US20030199753A1 US20030199753A1 US10/170,535 US17053502A US2003199753A1 US 20030199753 A1 US20030199753 A1 US 20030199753A1 US 17053502 A US17053502 A US 17053502A US 2003199753 A1 US2003199753 A1 US 2003199753A1
- Authority
- US
- United States
- Prior art keywords
- cutter
- biopsy
- needle
- probe assembly
- probe
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 239000000523 sample Substances 0.000 title claims abstract description 195
- 238000001574 biopsy Methods 0.000 title claims abstract description 152
- 238000002595 magnetic resonance imaging Methods 0.000 claims abstract description 58
- 238000003780 insertion Methods 0.000 claims abstract description 39
- 230000037431 insertion Effects 0.000 claims abstract description 39
- 230000004807 localization Effects 0.000 claims abstract description 35
- 239000012530 fluid Substances 0.000 claims abstract description 23
- 230000000007 visual effect Effects 0.000 claims abstract description 3
- 210000000481 breast Anatomy 0.000 claims description 30
- 230000006835 compression Effects 0.000 claims description 25
- 238000007906 compression Methods 0.000 claims description 25
- 230000033001 locomotion Effects 0.000 claims description 15
- 238000004891 communication Methods 0.000 claims description 12
- 230000001012 protector Effects 0.000 claims description 12
- 238000013519 translation Methods 0.000 claims description 10
- 239000000463 material Substances 0.000 claims description 4
- 238000000605 extraction Methods 0.000 claims 1
- 239000003302 ferromagnetic material Substances 0.000 claims 1
- 230000009977 dual effect Effects 0.000 abstract description 5
- 230000002265 prevention Effects 0.000 abstract 1
- 210000001519 tissue Anatomy 0.000 description 54
- 238000000034 method Methods 0.000 description 26
- NJPPVKZQTLUDBO-UHFFFAOYSA-N novaluron Chemical compound C1=C(Cl)C(OC(F)(F)C(OC(F)(F)F)F)=CC=C1NC(=O)NC(=O)C1=C(F)C=CC=C1F NJPPVKZQTLUDBO-UHFFFAOYSA-N 0.000 description 26
- 230000003902 lesion Effects 0.000 description 18
- 238000003384 imaging method Methods 0.000 description 15
- 230000007246 mechanism Effects 0.000 description 15
- 230000008901 benefit Effects 0.000 description 11
- 239000003550 marker Substances 0.000 description 10
- 238000005070 sampling Methods 0.000 description 10
- 238000011282 treatment Methods 0.000 description 10
- 206010018852 Haematoma Diseases 0.000 description 6
- 230000001225 therapeutic effect Effects 0.000 description 6
- 230000013011 mating Effects 0.000 description 5
- 229910052751 metal Inorganic materials 0.000 description 5
- 239000002184 metal Substances 0.000 description 5
- 210000003813 thumb Anatomy 0.000 description 5
- 238000003752 polymerase chain reaction Methods 0.000 description 4
- 210000000779 thoracic wall Anatomy 0.000 description 4
- 206010002091 Anaesthesia Diseases 0.000 description 3
- 206010028980 Neoplasm Diseases 0.000 description 3
- 230000037005 anaesthesia Effects 0.000 description 3
- 210000000038 chest Anatomy 0.000 description 3
- 239000002872 contrast media Substances 0.000 description 3
- 230000005291 magnetic effect Effects 0.000 description 3
- 102000004169 proteins and genes Human genes 0.000 description 3
- 108090000623 proteins and genes Proteins 0.000 description 3
- 238000002604 ultrasonography Methods 0.000 description 3
- RTAQQCXQSZGOHL-UHFFFAOYSA-N Titanium Chemical compound [Ti] RTAQQCXQSZGOHL-UHFFFAOYSA-N 0.000 description 2
- 239000000853 adhesive Substances 0.000 description 2
- 230000001070 adhesive effect Effects 0.000 description 2
- 229910052782 aluminium Inorganic materials 0.000 description 2
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 description 2
- 238000013459 approach Methods 0.000 description 2
- 201000011510 cancer Diseases 0.000 description 2
- SOYKEARSMXGVTM-UHFFFAOYSA-N chlorphenamine Chemical compound C=1C=CC=NC=1C(CCN(C)C)C1=CC=C(Cl)C=C1 SOYKEARSMXGVTM-UHFFFAOYSA-N 0.000 description 2
- 229960003291 chlorphenamine Drugs 0.000 description 2
- 238000012790 confirmation Methods 0.000 description 2
- 238000003745 diagnosis Methods 0.000 description 2
- 229910000701 elgiloys (Co-Cr-Ni Alloy) Inorganic materials 0.000 description 2
- 230000003211 malignant effect Effects 0.000 description 2
- 238000009607 mammography Methods 0.000 description 2
- 238000005259 measurement Methods 0.000 description 2
- HLXZNVUGXRDIFK-UHFFFAOYSA-N nickel titanium Chemical compound [Ti].[Ti].[Ti].[Ti].[Ti].[Ti].[Ti].[Ti].[Ti].[Ti].[Ti].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni] HLXZNVUGXRDIFK-UHFFFAOYSA-N 0.000 description 2
- 229910001000 nickel titanium Inorganic materials 0.000 description 2
- 230000037361 pathway Effects 0.000 description 2
- 239000008177 pharmaceutical agent Substances 0.000 description 2
- 230000005855 radiation Effects 0.000 description 2
- 238000004611 spectroscopical analysis Methods 0.000 description 2
- 229910001220 stainless steel Inorganic materials 0.000 description 2
- 239000010935 stainless steel Substances 0.000 description 2
- 238000001356 surgical procedure Methods 0.000 description 2
- 238000012360 testing method Methods 0.000 description 2
- 239000010936 titanium Substances 0.000 description 2
- 229910052719 titanium Inorganic materials 0.000 description 2
- 238000012546 transfer Methods 0.000 description 2
- 230000005641 tunneling Effects 0.000 description 2
- 238000012800 visualization Methods 0.000 description 2
- 102000004127 Cytokines Human genes 0.000 description 1
- 108090000695 Cytokines Proteins 0.000 description 1
- 238000000018 DNA microarray Methods 0.000 description 1
- 206010061619 Deformity Diseases 0.000 description 1
- 239000004606 Fillers/Extenders Substances 0.000 description 1
- 208000032843 Hemorrhage Diseases 0.000 description 1
- 239000002616 MRI contrast agent Substances 0.000 description 1
- 238000012307 MRI technique Methods 0.000 description 1
- 208000006994 Precancerous Conditions Diseases 0.000 description 1
- 238000001069 Raman spectroscopy Methods 0.000 description 1
- 241000237983 Trochidae Species 0.000 description 1
- 229920004738 ULTEM® Polymers 0.000 description 1
- 208000027418 Wounds and injury Diseases 0.000 description 1
- 230000005856 abnormality Effects 0.000 description 1
- 238000009825 accumulation Methods 0.000 description 1
- 238000004458 analytical method Methods 0.000 description 1
- 210000003484 anatomy Anatomy 0.000 description 1
- 229940035674 anesthetics Drugs 0.000 description 1
- 230000001093 anti-cancer Effects 0.000 description 1
- 230000004888 barrier function Effects 0.000 description 1
- 230000005540 biological transmission Effects 0.000 description 1
- 230000000740 bleeding effect Effects 0.000 description 1
- HJJVPARKXDDIQD-UHFFFAOYSA-N bromuconazole Chemical compound ClC1=CC(Cl)=CC=C1C1(CN2N=CN=C2)OCC(Br)C1 HJJVPARKXDDIQD-UHFFFAOYSA-N 0.000 description 1
- 238000004113 cell culture Methods 0.000 description 1
- 230000004663 cell proliferation Effects 0.000 description 1
- 239000000919 ceramic Substances 0.000 description 1
- 238000012512 characterization method Methods 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 238000013170 computed tomography imaging Methods 0.000 description 1
- 230000006378 damage Effects 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 238000001514 detection method Methods 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 238000002059 diagnostic imaging Methods 0.000 description 1
- 238000002405 diagnostic procedure Methods 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 208000035475 disorder Diseases 0.000 description 1
- 238000006073 displacement reaction Methods 0.000 description 1
- 230000003028 elevating effect Effects 0.000 description 1
- 230000008030 elimination Effects 0.000 description 1
- 238000003379 elimination reaction Methods 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 102000015694 estrogen receptors Human genes 0.000 description 1
- 108010038795 estrogen receptors Proteins 0.000 description 1
- 238000007387 excisional biopsy Methods 0.000 description 1
- 230000005294 ferromagnetic effect Effects 0.000 description 1
- 239000000835 fiber Substances 0.000 description 1
- 238000000684 flow cytometry Methods 0.000 description 1
- 239000012634 fragment Substances 0.000 description 1
- 239000003193 general anesthetic agent Substances 0.000 description 1
- 230000002068 genetic effect Effects 0.000 description 1
- 230000004153 glucose metabolism Effects 0.000 description 1
- 239000003102 growth factor Substances 0.000 description 1
- 230000002962 histologic effect Effects 0.000 description 1
- 238000003364 immunohistochemistry Methods 0.000 description 1
- 238000002513 implantation Methods 0.000 description 1
- 238000007386 incisional biopsy Methods 0.000 description 1
- 230000000977 initiatory effect Effects 0.000 description 1
- 208000014674 injury Diseases 0.000 description 1
- 238000011835 investigation Methods 0.000 description 1
- 238000001499 laser induced fluorescence spectroscopy Methods 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 230000003278 mimic effect Effects 0.000 description 1
- 230000002438 mitochondrial effect Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000013188 needle biopsy Methods 0.000 description 1
- 210000005036 nerve Anatomy 0.000 description 1
- 238000012633 nuclear imaging Methods 0.000 description 1
- 238000010899 nucleation Methods 0.000 description 1
- 230000003287 optical effect Effects 0.000 description 1
- 230000036407 pain Effects 0.000 description 1
- 238000002559 palpation Methods 0.000 description 1
- 239000012188 paraffin wax Substances 0.000 description 1
- 230000007170 pathology Effects 0.000 description 1
- 230000000149 penetrating effect Effects 0.000 description 1
- 238000012831 peritoneal equilibrium test Methods 0.000 description 1
- 230000010287 polarization Effects 0.000 description 1
- 238000012636 positron electron tomography Methods 0.000 description 1
- 238000012877 positron emission topography Methods 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 238000004393 prognosis Methods 0.000 description 1
- 230000000750 progressive effect Effects 0.000 description 1
- 230000035755 proliferation Effects 0.000 description 1
- 230000002285 radioactive effect Effects 0.000 description 1
- 238000001959 radiotherapy Methods 0.000 description 1
- 238000011084 recovery Methods 0.000 description 1
- 239000011347 resin Substances 0.000 description 1
- 229920005989 resin Polymers 0.000 description 1
- 238000007789 sealing Methods 0.000 description 1
- 238000002603 single-photon emission computed tomography Methods 0.000 description 1
- 210000004872 soft tissue Anatomy 0.000 description 1
- 230000000087 stabilizing effect Effects 0.000 description 1
- 238000007920 subcutaneous administration Methods 0.000 description 1
- 238000001931 thermography Methods 0.000 description 1
- 210000000115 thoracic cavity Anatomy 0.000 description 1
- 238000012285 ultrasound imaging Methods 0.000 description 1
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B10/00—Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
- A61B10/02—Instruments for taking cell samples or for biopsy
- A61B10/0233—Pointed or sharp biopsy instruments
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B10/00—Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
- A61B10/02—Instruments for taking cell samples or for biopsy
- A61B10/0233—Pointed or sharp biopsy instruments
- A61B10/0283—Pointed or sharp biopsy instruments with vacuum aspiration, e.g. caused by retractable plunger or by connected syringe
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/34—Trocars; Puncturing needles
- A61B17/3403—Needle locating or guiding means
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/70—Means for positioning the patient in relation to the detecting, measuring or recording means
- A61B5/708—Breast positioning means
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B10/00—Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
- A61B10/02—Instruments for taking cell samples or for biopsy
- A61B10/0233—Pointed or sharp biopsy instruments
- A61B10/0266—Pointed or sharp biopsy instruments means for severing sample
- A61B10/0275—Pointed or sharp biopsy instruments means for severing sample with sample notch, e.g. on the side of inner stylet
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B10/00—Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
- A61B10/02—Instruments for taking cell samples or for biopsy
- A61B2010/0208—Biopsy devices with actuators, e.g. with triggered spring mechanisms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B2017/0046—Surgical instruments, devices or methods, e.g. tourniquets with a releasable handle; with handle and operating part separable
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B2017/00831—Material properties
- A61B2017/00902—Material properties transparent or translucent
- A61B2017/00911—Material properties transparent or translucent for fields applied by a magnetic resonance imaging system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/34—Trocars; Puncturing needles
- A61B2017/347—Locking means, e.g. for locking instrument in cannula
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
- A61B90/36—Image-producing devices or illumination devices not otherwise provided for
- A61B90/37—Surgical systems with images on a monitor during operation
- A61B2090/374—NMR or MRI
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/05—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves
- A61B5/055—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves involving electronic [EMR] or nuclear [NMR] magnetic resonance, e.g. magnetic resonance imaging
Definitions
- the present invention relates, in general to devices for tissue sampling and, more particularly, to an improved device for core biopsy probes stereotopically positioned by coordinates derived from magnetic resonance imaging (MRI) scans for acquiring subcutaneous biopsies and for removing lesions.
- MRI magnetic resonance imaging
- a biopsy may be done either in an open procedure or in a percutaneous procedure.
- a scalpel is used by the surgeon to create a large incision in the tissue in order to provide direct viewing and access to the tissue mass of interest. Removal of the entire mass (excisional biopsy) or a part of the mass (incisional biopsy) is done.
- a needle-like instrument For a percutaneous biopsy, a needle-like instrument is used through a very small incision to access the tissue mass of interest and to obtain a tissue sample for a later examination and analysis.
- the advantages of the percutaneous method as compared to the open method are significant: less recovery time for the patient, less pain, less surgical time, lower cost, less risk of injury to adjacent bodily tissues such as nerves, and less disfigurement of the patient's anatomy.
- Use of the percutaneous method in combination with artificial imaging devices such as X-ray and ultrasound has resulted in highly reliable diagnoses and treatments.
- the instrument is a type of image-guided, percutaneous, coring, breast biopsy instrument. It is vacuum-assisted, and some of the steps for retrieving the tissue samples have been automated.
- the physician uses this device to capture “actively” (using the vacuum) the tissue prior to severing it from the body. This allows the sampling tissues of varying hardness.
- the device can also be used to collect multiple samples in numerous positions about its longitudinal axis, and without removing the device from the body. These features allow for substantial sampling of large lesions and complete removal of small ones.
- the instrument In actual clinical use for breast biopsy the instrument (probe and driver assembly) is mounted to the three axis-positioning head of an x-ray imaging machine.
- the three axis-positioning heads is located in the area between the x-ray source and the image plate.
- the x-ray machines are outfitted with a computerized system which requires two x-ray images of the breast be taken with the x-ray source at two different positions in order for the computer to calculate x, y and z axis location of the suspect abnormality.
- the x-ray source In order to take the stereo x-ray images the x-ray source must be conveniently movable.
- the x-ray source therefore is typically mounted to an arm which, at the end opposite the x-ray source, is pivotally mounted to the frame of the machine in the region of the image plate.
- a hand held MAMMOTOMETM is desirable because the handpiece on the MAMMOTOMETM may be held approximately parallel to the chest wall of the patient for obtaining tissue portions closer to the chest wall than may be obtained when using an instrument that is mounted to an electromechanical arm.
- a further problem not infrequently encountered during core needle biopsy is the development of a hematoma at the biopsy site during the procedure.
- An accumulating hematoma can be problematic during MRI-guided biopsy because residual contrast agent circulating in the hematoma can mimic enhancement in a suspicious lesion.
- the accumulation of air at the biopsy site can cause susceptibility artifacts that can potentially interfere with the fat-suppression MRI techniques at the biopsy site cavity.
- the hand-held biopsy device presents a long, external handle that is inappropriate for closed magnet MRI machines.
- the hand-held biopsy device allows great freedom in lateral and angular orientation, in some instances it is preferable to specifically position the biopsy probe.
- the MRI machine may provide very accurate stereotactic placement information that is only partially utilized in inserting the probe.
- the hand-held biopsy device is inserted through an opening in a compression plate, so some two-dimensional alignment is provided.
- the angle and depth of insertion the probe tends to vary, especially without continual reimaging of the probe during insertion, which is particularly inappropriate for closed MRI magnets.
- the vacuum assist reduces occurrence of a hematoma and draws in tissue to increase the sample size without repositioning the probe; however, current clinical procedures often require additional invasive procedures to the biopsy site to administer anesthesia or to perform additional diagnostic or treatment procedures.
- the invention overcomes the above-noted and other deficiencies of the prior art by providing a detachable probe assembly that is physically located with respect to Magnetic Resonance Imaging (MRI) stereotopic guidance so that a biopsy site location is accurately and rapidly acquired and maintained.
- MRI Magnetic Resonance Imaging
- Being separately fixable to a localization mechanism used with a breast coil allows for use of core biopsy procedures in closed MRI machines without repeated insertions of the biopsy probe.
- Even if used with an open MRI machine the detachable nature avoids having to hold in place for an extended period of time by hand a biopsy handle, which provides a cutter to the biopsy probe.
- the detachable biopsy probe includes a dual lumen elongated tubular needle.
- a vacuum chamber lumen is in fluid communication with the sample opening to vacuum assist the taking of a biopsy sample.
- the probe assembly includes an engagement member that is readily spatially fixed. The engagement member provides access to the vacuum chamber lumen for fluid or gas transfer and provides access to the cutter lumen by the biopsy handle and by other diagnostic and therapeutic tools.
- a biopsy tool is provided with a detachable probe assembly with a needle having at least one lumen for taking biopsies.
- An engagement member at the proximal end of the needle allows attachment to a mounting device that positions the needle.
- the biopsy tool also includes a biopsy handle that readily engages and disengages to the detachable probe so that diagnostic scans can be performed even within the narrow confines of some scanning machines.
- a core biopsy system is disclosed with the biopsy tool mechanically powered remotely via a power cord from a control module.
- a localization mechanism is used in conjunction with a breast coil to position the detachable probe assembly and to guide the probe assembly when inserted into a patient's breast to be MRI imaged. Accurate positioning of the probe assembly is enhanced by alignment guides that may be referenced to stereotactic coordinates provided by the MRI scan, aiding in the accurate insertion of the probe the designated biopsy site.
- FIG. 1 is plan view of the biopsy instrument, mounting fixture, an Magnetic Resonance Imaging (MRI) breast coil fixture, and patient support table in working relationship outside the confines of an MRI machine.
- MRI Magnetic Resonance Imaging
- FIG. 2 is a plan view of the biopsy instrument, localization fixture, partially cut away MRI breast coil fixture, patient support table, and in working relationship and configured for insertion into a MRI machine.
- FIG. 3 is a plan view of the localization fixture, partially cut away MRI breast coil fixture, patient support table, and a detached probe assembly of the biopsy instrument mounted to the localization fixture, in working relationship and configured for insertion into the MRI machine.
- FIG. 4 is an isometric view of the biopsy instrument disassembled into a biopsy instrument handle, probe housing, and probe.
- FIG. 4A is a frontal isometric detail view of an alternative needle tip of a biopsy instrument.
- FIG. 5 is an exploded isometric view of the biopsy instrument handle.
- FIG. 6 is an exploded isometric view of the probe of the biopsy instrument of FIG. 4.
- FIG. 7 is a transverse cross section of the probe of the biopsy instrument of FIG. 4 along lines 7 - 7 .
- FIG. 8 is an enlarged isometric view of the interface between the handle and probe housing illustrating the visual confirmation elements that indicate the position of the distal end of the cutter.
- FIG. 9 is a fragmentary plan view in partial section of the distal portion of the handle and probe housing and assembly, illustrating the disconnect feature with the cutter retracted.
- FIG. 10 is a fragmentary plan view in partial section of the distal portion of the handle and probe housing and assembly, illustrating the tolerance take-out feature and the disabled disconnect feature when the cutter is advanced.
- FIG. 11 is an isometric view of the biopsy instrument with the handle portion disconnected from a tower/bracket localization fixture and probe assembly.
- FIG. 12 is an isometric view of the biopsy instrument mounted to the tower/bracket localization fixture of FIG. 11.
- FIG. 13 is an exploded isometric view of the tower/bracket localization version of the localization fixture and probe assembly of the biopsy instrument.
- FIG. 14 is a side elevation view of the biopsy instrument in partial section to illustrate a tower/bracket support for stabilizing the handle and probe assembly of the biopsy instrument.
- FIG. 15 is a side elevation view of the dual tower support version of the localization fixture positioning a detachable probe assembly with its dual lumens closed by a vacuum conduit and an obturator stylet.
- FIG. 16 is an isometric view of the biopsy instrument mounted to a dual tower localization fixture.
- FIG. 17 is an isometric view of the slide plate of a localization fixture guiding a scissors support in a lowered position for vertically orienting a biopsy instrument.
- FIG. 18 is an isometric view of the slide plate of a localization fixture guiding the scissors support in a raised position for vertically orienting a biopsy instrument.
- FIG. 19 is a sequence of clinical operations for using the detachable MRI-guided biopsy instrument of FIG. 1 in both open and closed MRI machines.
- FIG. 20 is an isometric view of a tip protector mounted onto a needle tip of the detachable probe assembly of FIG. 11.
- FIG. 21 is an isometric detail view of the trip protector of FIG. 20.
- FIG. 1 depicts a core biopsy instrument system 10 that is vacuum assisted, detachable, and compatible with use in a Magnetic Resonance Imaging (MRI) machine, such as the depicted closed MRI machine 12 .
- the core biopsy instrument system 10 includes an MRI-compatible biopsy tool 14 that is selectably attached to a localization mechanism or fixture 16 to accurately and rapidly perform core biopsies of breast tissue with a minimum of insertions of a biopsy probe.
- a control module (not shown) senses encoder position signal and switch signals from the biopsy tool 14 and provides mechanical and vacuum power to the biopsy tool 14 via power cord 18 .
- a patient 20 is lying prone upon a patient support table 22 , depicted in FIG. 1 as removed from a magnet bore 24 of the MRI machine 12 .
- the patient's chest rests upon a top surface 26 of a chest support 28 , the top surface 24 having openings 30 , 32 for allowing the patient's breasts to hang downward for imaging and treatment.
- the right opening 30 is depicted with the localizer fixture 16 laterally positioned to cooperate with a medial compression plate (not shown) to longitudinally fix and compress the patient's right breast.
- Antenna elements are placed about the opening 30 to detect radio frequency (RF) signals emanated by breast tissue induced by a strong magnetic field from the MRI bore 24 .
- the chest support 28 and antennas are generally termed a breast coil 34 .
- the biopsy tool 14 includes a biopsy handle 36 that is attachable to a probe assembly 38 .
- the localization fixture 16 accurately positions the probe assembly 38 for stereotactic mammography biopsy procedures for a specific biopsy site location for a distal tip 40 of the probe assembly 38 .
- This location is identified by an X-axis coordinate that is horizontal and longitudinal with respect to the patient (depicted as right to left in FIGS. 1 - 2 ).
- a Z-axis is defined as the vertical height, with the X and Z axis orthogonally defined on a lateral compression plate 42 of the localization fixture 16 , the lateral compression plate 42 cooperating with the medial compression plate (not shown) to fix and compress the patient's breast.
- This location is also defined in terms of depth of insertion, or Y-axis, which is depicted as up and down in the FIGS. 1 - 2 .
- a probe assembly mounting device 44 connects to a probe housing 46 of the biopsy tool 14 .
- the mounting device 44 includes alignment positioning guides (described in more detail below) to orient the probe housing 46 , and hence the probe assembly 38 , to the desired X-Y-Z coordinate.
- a depth slide 48 allows mounting of the probe assembly 38 with the distal tip 40 extends outside of the opening 30 and lateral compression plate 42 . Thereafter, the probe assembly 38 is guided along the Y-axis by the depth slide 48 while maintaining the selected X-Z-axes coordinates.
- the mounting device 44 advantageously supports the biopsy handle 36 when attached to the probe assembly 38 as depicted in FIG. 2 to maintain the angle of insertion of the probe assembly 38 .
- the probe housing 46 provides access to the interior of the probe assembly 38 via a vacuum lumen access conduit 50 for draining fluids, inserting fluids such as anesthetics.
- FIG. 3 depicts the core biopsy instrument system 10 with the biopsy handle 36 removed and the depth slide 48 moved inward to allow insertion of the patient support table 22 into the narrow confines of the MRI magnet bore 24 .
- the surgeon may take full advantage of the stereotactic coordinates provided by the MRI machine 12 , even if using a closed magnetic bore 24 .
- the stereotactic derived coordinates may be used even if not actively imaging the probe assembly 38 during insertion.
- the localization fixture 16 enables the surgeon to manually insert the probe assembly 38 with an indication of current depth. The surgeon is given tactile feedback while doing so and can thus ascertain to a significant degree the density and hardness of tissue being encountered.
- a mechanism to provide mechanical advantage to the pedestal may enable a controlled and deliberate insertion of the probe into the tissue.
- a means to prevent the pedestal and probe assembly from moving proximally once inserted to the proper location within the tissue would aid in maintaining the proper position of the probe within the tissue. With the probe assembly 38 maintained in the correct location after insertion, the probe assembly 38 provides access for other diagnostic and therapeutic tools and fluid treatments.
- a Y-axis adjustment mechanism may be incorporated into the localization fixture 16 to provide mechanical advantage, thereby achieving a controlled and deliberate insertion of the probe assembly 38 .
- the Y-axis adjustment mechanism may incorporate a frictional, ratcheting or locking feature to prevent inadvertent movement of the probe assembly 38 after placement at the desired biopsy location. Examples of such Y-axis adjustment include but are not limited to a thumb wheel in geared communication between the probe assembly mounting device 150 and the localizer support frame 126 .
- FIG. 4 depicts the biopsy tool 14 with the biopsy handle 36 depicted as readily attached to the probe housing 46 , which in turn is readily attached to the probe assembly 38 .
- the probe assembly 38 includes a male cylindrical mating portion 52 presenting a central cutter opening 54 on a proximal end that is aligned with the longitudinal length of a cutter lumen 56 of an elongated needle 58 .
- the cutter lumen 56 communicates with a sample port 60 laterally presented near a needle tip 62 at the distal end of the needle 58 .
- the needle tip 62 is for penetrating the soft tissue of a surgical patient.
- the needle tip 60 is sharpened and is preferably made from an MRI compatible resin such as ULTEM or VECTRA.
- the needle tip 60 is a three-sided pyramidal shaped point, although the needle tip 62 configuration may also have other shapes and/or inserts.
- a sharpened blade inserted into the tip would reduce the probe insertion force into tissue.
- the blade could be made of titanium, stainless steel, nitinol, aluminum, Elgiloy, etc.
- the illustrative embodiment advantageously includes a material that leaves a small, but not troublesome artifact on an MRI scan.
- FIG. 4A depicts a needle tip 62 ′ having a conical shape with a distally presented X-shaped slot 63 for receiving a pointed, sharpened blade 65 that reduces the probe insertion force into tissue.
- the blade 65 could be made of titanium, stainless steel, nitinol, aluminum, Elgiloy, ceramic, etc. It will be appreciated that other shapes of sharpened blade 65 may be used, such as a single pointed surface in a distally presented single slot rather than two perpedicularly crossed, pointed surfaces as depicted.
- a cutter element or an obturator stylet is advanced inside the cutter lumen 56 to block the sample port 60 during insertion.
- the sample port 60 is exposed to allow tissue to enter.
- a vacuum may be presented to a “sample bowl” inside the cutter lumen 56 near the sample port 60 by applying vacuum power through a vacuum chamber lumen 64 that communicates along the longitudinal length of the needle 58 to the male cylindrical mating portion 52 .
- a series of small holes allow gas and fluid to enter the vacuum chamber lumen 64 from the sample port 60 but prevent tissue samples from entering.
- Annular rings 66 about the cylindrical mating portion 52 grip and seal to an interior of a female cylindrical mating portion 68 on the probe housing 46 .
- a proximal vacuum port (not shown in FIG. 4) communicates with a vacuum passage (not shown) in the probe housing 46 .
- the engagement between the mating portions 52 , 68 advantageously allows rotation of the needle 58 with a thumb wheel 70 annularly presented near the proximal end of the needle 58 .
- the radial opening presented by the annual rings 66 maintains communication between the vacuum passage in the probe housing 46 and the vacuum chamber lumen 64 regardless of radial orientation of the needle 58 .
- the sample port 60 may be presented to tissue at any and all radial positions about the distal end of the needle 58 . With the assistance of vacuum, a large volume of tissue may be selectably drawn into the sample bowl for biopsy sampling.
- the probe housing 46 includes laterally presented attachment prongs 72 for mounting to the localization fixture 16 .
- the probe housing 46 presents a proximally directed cuboidal engagement member 74 with longitudinally aligned vertical and horizontal grooves 76 for flanges 78 from the biopsy handle 36 .
- the probe housing 46 also receives hooked locking tabs 80 , 82 on the distal engaging end of the biopsy handle 36 for selective locking and unlocking under the influence of a pair of opposing depression grips 84 , 86 attached to respective tabs 80 , 82 .
- the biopsy handle 36 includes a sample window 88 for extracting any tissue sample withdrawn from the cutter lumen 52 under the influence of a vacuum passing through the cutter, as described in more detail below.
- FIG. 5 depicts a disassembled biopsy handle 36 that contains the means for translating and rotating a cutter 90 within the cutter lumen 56 .
- two rotating mechanical power sources are presented to the proximal end of the biopsy handle 36 through the power cord 18 to provide the independent translation and rotation motions. These two rotating mechanical power sources enter through a cord opening 92 defined between a removable shell 94 and a bottom shell 96 , the two held together by screws. Alternately, one rotating mechanical power source could drive both translation and rotation elements. Via standard gearing means, the single power source could be appropriately connected to both of the drive elements.
- the removable shell 94 is removed when assembling a power cord 18 to the handle 36 .
- a lower gear housing 98 is supported upon the bottom shell 96 and cooperates with a top shell 100 to constrain movement of an elongate drive screw 102 , an elongate axial screw 104 and cutter carriage 106 .
- both screws 102 , 104 are allowed to rotate, positioned parallel to one another and the longitudinal axis of the cutter lumen 56 .
- Each screw 102 , 104 is driven by a respective power source from the power cord 18 .
- the drive screw 102 passes through the carriage 106 and interacts with corresponding ridges therein to impart a longitudinal translation corresponding to the direction and rate of rotation of the drive screw 102 .
- a single rotary power source may be used as an alternative to two independent rotating mechanical power sources.
- a transmission mechanism at the biopsy handle 36 may convert the single rotary power source into the two motions, translation and rotation.
- the single rotary power source may directly supply both a translation and rotary motion. Such a translating and rotating power cable would be coupled to the cutter 90 to directly control its movement.
- the cutter 90 is an elongate tube with a sharpened distal end for cutting tissue presented within the distal end of the cutter lumen 56 .
- the proximal end of the cutter 90 includes a cutter gear 108 that is exposed through a gear window 110 of the carriage 106 to mesh with the axial screw 104 for axial rotation of the cutter 90 .
- a tissue remover 111 is a tube that is fixedly aligned with the longitudinal axis to enter the proximal end of the cutter 90 .
- the tissue remover 111 extends up to the sample window 88 and has a vacuum selectably applied to it by the control module.
- vacuum from the tissue remover 111 draws the sample to the distal end of the cutter 90 for retraction to the sample window 88 , whereupon the sample encounter the tissue remover 111 and is dislodged for exiting the biopsy tool 14 .
- the carriage 106 includes distally projected guides 112 , 114 that advantageously take-out slack between biopsy handle 36 and the probe housing 46 , as well as providing indicia to the surgeon as to the depth of translation of the cutter 90 . Taking out slack between the assembled parts of the handle 36 and housing 46 advantageously minimizes the deadzone length of the distal end of the needle 58 .
- the cutter 90 should completely translate past the sample port 60 in order to reliably cut a sample. To ensure a full cut, the cutter 90 should translate the maximum distance expected for the assembly. If variation exists in manufacturing tolerances between the engagement components, then a further distance has to be included in the cutter lumen 56 distal to the sample port 60 to accommodate the over-travel.
- the needle tip 62 must be advanced farther than desirable in some instances, preventing placement of the sample port 60 near critical body tissues.
- the guides 112 , 114 contact the probe housing 46 , causing movement of the housing 46 to its maximum, distal position.
- FIG. 5 also depicts a brace 116 and brace arm 118 that are employed in one version of the localization fixture 16 to support the weight and maintain the alignment of the handle 36 . Thereby, flexure of the assembly is avoided that may place a load on the probe assembly 38 , and thus unwanted movement of the needle 58 from the desired biopsy site location.
- FIGS. 6 - 7 depict the needle 58 of FIG. 4 and described more fully in the aforementioned application Ser. No. ______ , entitled “AN MRI COMPATIBLE SURGICAL BIOPSY DEVICE”.
- elongated needle 58 is formed from a left body member 120 and a right body member 121 on either side of the longitudinal axis.
- the edges of the halves 120 and 121 are gated for easy part filling, and the edges are stepped with ridges that allow the two halves 120 and 121 to attach together with ease.
- the two halves 120 , 121 are adhesively attached to one another.
- a cutter tube liner 122 is inserted between the two halves 120 , 121 to provide a smooth surface for the cutter 90 , especially by preventing adhesive from entering the cutter lumen 56 during assembly; as well as, aid in pneumatically sealing the cutter lumen from the vacuum lumen.
- FIG. 8 shows an enlarged view of the engagement of the handle 36 to the probe housing 46 , with the advanced cutter 90 evident through the window 88 .
- the guides 112 , 114 are advanced almost into contact with the probe housing 46 , indicating that the distal end of the cutter 90 is approaching its furthest translation.
- the guides 112 , 114 contact the probe housing 90 when at or near this extreme to take-out any tolerance.
- Indicia on the side of the guides 112 , 114 may be referenced by the surgeon to determine the position of the cutter.
- FIGS. 8 - 10 show that each grip 84 , 86 includes a respective inwardly projecting member 124 , 125 that contact the guides 112 , 114 when the cutter 90 is distally advanced, thereby preventing removal of the handle 36 .
- the cutter 90 is retracted, allowed the depression of the grips 84 , 86 , unlocking the hooked locking tabs 80 , 82 from the probe housing 46 .
- cutter carriage 106 is advanced, the guides 112 , 114 are contacting the probe housing 46 , thereby removing any longitudinal gap between the hooked locking tabs 80 , 86 and the probe housing 46 .
- FIGS. 11 - 14 depicts a localization fixture 16 that includes means for accurately positioning the probe assembly 38 and supporting the biopsy handle 36 .
- a localizer support frame 126 is formed from the compression plate 42 in a hinged, orthogonal relation to a horizontal slide plate 128 , both laterally attached to one another by gussets 130 , 132 .
- Rods 134 , 136 horizontally pass through the compression plate to adjustably attach to the medial compression plate (not shown) for compressing the patient's breast.
- Apertures, depicted as parallel rows of slots 138 , in the compression plate 42 are provided to obtain access to a desired biopsy site location while providing enough remaining structure in the compression plate 42 for adequate contact with the patient's breast.
- the apertures may be a series of holes aligned both horizontally and vertically or simply one large opening.
- the apertures may be a series of holes aligned both vertically and vertically, parallel columns of slots, or a large opening of other shapes.
- portions of the compression plate 42 may be permeable to allow an aperture to be formed as needed.
- the desired biopsy site location is stereotopically determined during an MRI scan with reference to a fiducial marker 140 that presents a small artifact.
- the fiducial marker 140 is contained within a fiducial marker holder 142 that may be placed at a convenient location on the compression plate 42 , accurately placed with reference to indents spaced along the slots 138 .
- the fiducial marker may be embedded or affixed to the compression plate 42 .
- the localizer support frame 126 defines and provides the guide for positioning the probe assembly 38 .
- the X-Y-Z axes are defined with regard to the slots 138 and compression plate 42 .
- the vertical dimension, or Z-axis, and horizontal dimension, or X-axis are defined by the surface of the compression plate 42 .
- the depth dimension, or Y-axis is defined as distance away from the plane of the compression plate 42 .
- the horizontal slide plate 128 includes laterally aligned front and back rails 144 , 146 for setting the X-axis coordinate. Horizontal indicia 148 along the front rail 144 give the surgeon an accurate measurement of the position of a probe assembly mounting device 150 .
- a first version of the mounting device 150 is depicted that uses a single vertical pedestal 152 to position and support the probe assembly 38 .
- the biopsy handle 36 is supported by the brace 116 connected to the proximal underside of the handle 36 to a handle support rod 156 that is slid through a rod hole 158 to the corresponding side of the vertical pedestal 152 .
- the appropriate height for the brace 116 is determined by selecting one of a range of slots arrayed along the underside of the handle, thereby pivoting the brace 116 about the brace arm 118 whose first end slidably pivots within a slot 162 in the middle of the brace 154 and second end attaches to the distal end of the handle 36 .
- an obturator stylet 164 is slide into the cutter lumen 56 to close the cutter port 88 .
- the stylet 164 may have radially oriented through holes near its distal end to maintain fluid communication between the tissue and the vacuum lumen. Alternately, the stylet 164 may be partially withdrawn, allowing the cutter port 88 to be in fluid communication with the conduit 50 .
- a slide 166 includes a grooved underside to horizontally slide on rails 144 , 146 of the slide plate 128 .
- the slide 166 also includes a central channel 168 oriented in the Y-axis depth dimension to guide the pedestal 152 as it slides in the Y-axis direction.
- Sufficient range of motion in depth is achieved with a pivoting depth slide 170 , aligned and pivotally attached to the slide 166 . With the pivoting depth slide 170 in its lowest, horizontal position, the pedestal 152 may be slid outward sufficiently for the probe assembly 38 to be out of the compression plate 42 .
- the pivoting depth slide 170 may be pivoted upward or otherwise removed to allow the patient to be transferred into the magnet 24 .
- Depth indicia 172 along the central channel 168 give the surgeon an indication of the insertion depth of the probe assembly 38 .
- a vertical slide 174 slides on the pedestal 152 for vertical positioning along the Z-axis, with a measurement provided by vertical indicia 176 on the pedestal 152 .
- Holes 178 on each lateral side of the vertical slide 174 allow mounting of the probe housing 46 on either side by insertion of attachment probes 72 .
- FIGS. 15 - 16 depict a second version of the mounting device 150 that uses a second vertical pedestal 180 in lieu of a brace assembly to support the handle 36 .
- the probe housing 46 is also depicted as attached to the opposite side of the first vertical pedestal 152 .
- a second vertical slide 181 of the second vertical slide 180 advantages contacts the first vertical slide 174 , as shown in FIG. 16, so that setting the vertical height for both is accomplished in one step.
- Each vertical slide 174 , 181 moves in a ratchet fashion against its respective vertical pedestal 152 , 180 , and thus remains in position after being separated from one another as shown in FIG. 15.
- the close nesting of the two vertical pedestals 174 , 180 enhances the ability to minimize the proximal displacement of the localization fixture 16 when used within the close confines of a closed MRI magnetic bore 24 .
- the second vertical slide 181 includes a shaped area that engages the underside of the handle 36 in such a way as to correctly align the handle 36 at the same X-axis horizontal dimension as the probe assembly 38 .
- FIGS. 17 - 18 depict a third version of the mounting device 150 wherein the slide 166 and pedestal 152 are replaced with a scissors table assembly 182 that includes a first slide 184 for horizontal movement on the slide plate 128 .
- a depth slide 186 is nested within a top channel 188 of the first slide 182 .
- a pair of scissors braces 190 are extended when drawn together with a screw 192 , thereby elevating the depth slide 186 with respect to the first slide 184 .
- the third version of the mounting device 150 advantageously provides a level support for both the detachable probe assembly 38 as well as the biopsy handle 36 without having to perform two vertical adjustments. This version also allows a single means to attach the probe to the pedestal, as well as not having to perform two separate attachments for each of the handle 36 and probe assembly 38 .
- FIG. 19 depicts a sequence of operations, or method 200 , for performing an MRI-guided breast core biopsy that accurately and quickly performs a core biopsy even in a closed MRI. Moreover, the method takes full advantage of the stereotopic location information rendered from the MRI scan to position an MRI compatible core biopsy probe without the necessity of continuous imaging of the distal tip of the biopsy probe.
- the equipment Prior to performing a clinical breast biopsy, the equipment is initialized to ensure proper function.
- the probe that comprises a needle, thumb wheel and housing is assembled with the handle.
- the assembled biopsy tool is connected via a power cord to a control module and the system is powered up, initiating power up logic in the control module (block 204 ). Parameters for rotation speed and translation distances are loaded. If the control module determines that the system has not been powered up recently, such as 60 minutes, then initialization logic is performed. Thus, translational drivetrain initialization is performed (block 206 ); rotational drivetrain initialization is performed (block 208 ); and vacuum system initialization is performed (block 210 ). If initialization is not required, then blocks 206 - 210 are bypassed.
- the patient's breast is immobilized in the localization mechanism (block 212 ) and the patient is moved into the MRI magnet bore (block 214 ).
- An MRI scan is performed to stereotopically locate suspicious tissue with reference to a movable fiduciary marker on the localization mechanism (block 216 ).
- the patient is then removed (block 218 ), which is not necessary for an open bore.
- Anesthesia is administered prior to the minimally invasive vacuum assisted core biopsy procedure (block 220 ).
- the positioning guides on the localization mechanism are positioned for insertion to the predetermined biopsy site (block 222 ).
- insertion may be enhanced by use of an insertion tool installed through the probe assembly 38 (block 224 ).
- an ultrasonic cutting tip, extender, and outer tube assembly may be inserted through the probe assembly 38 through a slot in the needle tip 62 , or exiting from the sample port 60 to be snapped onto the needle tip 62 .
- This could be accomplished with a housing on the ultrasonic device that is configured to snap onto the needle 58 , similarly to how a trocar obturator snaps onto the trocar cannula. Then, the ultrasonic tip is energized prior to insertion into the patient.
- the probe assembly is mounted on the localization mechanism (block 226 ) at the designated X-Z coordinate and with the mounting device withdrawn along the depth axis.
- the cutter lumen is sealed with an obturator stylet (block 228 ), if not otherwise sealed by a tool in block 224 .
- the vacuum lumen may be similarly sealed (e.g. stopcock attached to vacuum lumen access conduit 50 ) or be used to aspirate fluid and tissue during insertion.
- the probe is advanced along the Y-axis, guided by the localization mechanism to avoid misalignment (block 230 ). Once in place, if an insertion enhancement tool was installed in block 224 , then this tool is withdrawn through the cutter lumen of the probe assembly (block 232 ).
- various fluid transfers may advantageously take place through the probe assembly (block 234 ).
- vacuum may be applied through the vacuum lumen with the sample port exposed to drain any hematoma or air bubble formed at the biopsy site.
- Treatment fluids may be inserted directly to the biopsy site, such as anesthesia or MRI contrast agent. If the patient is to be scanned in a closed magnet bore, then the patient is moved back into the bore for scanning (block 236 ).
- vacuum may optionally be applied to the biopsy site to draw in suspicious tissue into the bowl of the sample port for confirmation prior to cutting the sample (block 238 ). Then, the MRI scan is performed to confirm placement of tissue in the bowl of the probe assembly, and adjustment of the probe assembly placement and re-scans are performed as required (block 240 ).
- Sample mode is selected through the control module to perform the sequence of steps to translate and rotate the cutter according to predetermined settings, with vacuum assist to draw in the sample and to retract the sample along with the cutter to the sample window (block 244 ). If more samples at this biopsy site are required for diagnostic or for treatment purposes (block 246 ), then the thumb wheel is rotated to reorient the sample port to another angle (block 248 ), and sample mode is performed again by returning to block 244 .
- the probe assembly After the core biopsy is performed, the probe assembly provides an excellent opportunity for other minimally invasive diagnostic procedures and treatments without the necessity for another insertion. If the biopsy handle is installed, such as in an open MRI magnet bore, the handle is removed so that the detachable probe assembly may be accessed (block 250 ).
- Examples of tools that may be inserted through the probe assembly include: (1) gamma detectors; (2) energized tunneling tips to reduce tunneling forces; (3) inserts to aid in reconstruction of removed tissue (e.g., one or two sided shaver inserts); (4) spectroscopy imaging devices; (5) general tissue characterization sensors ⁇ e.g., (a) mammography; (b) ultrasound, sonography, contrast agents, power Doppler; (c) PET and FDG ([Flourine-18]-2-deoxy-2-fluoro-glucose); (d) MRI or NMR, breast coil; (e) mechanical impedance or elastic modulus; (f) electrical impedance; (g) optical spectroscopy, raman spectroscopy, phase, polarization, wavelength/frequency, reflectance; (h) laser-induced fluorescence or auto-fluorescence; (i) radiation emission/detection, radioactive seed implantation; (j) flow cytometry; (k) genomics, PCR (polymerase
- a tissue marker is inserted through the probe assembly so that subsequent ultrasonic, X-ray, or MRI scans will identify the location of the previous biopsy (block 252 ) and the probe is removed (block 254 ).
- FIGS. 20 - 21 depict a tip protector 260 that advantageously protects the needle tip 62 of the probe assembly 38 prior to insertion into tissue and simplifies localization of the probe assembly 38 in some instances. Furthermore, the tip protector 260 does not interfere with pre-clinical setup procedures (e.g., testing for vacuum leaks).
- the tip protector 260 includes an attachment member 262 with clips onto the needle 58 without obstructing the sample port 60 .
- a distal portion of the tip protector completely encompasses the needle tip 62 with a protection member, depicted as a hemispheric disk 264 , that may be placed in contact with a patient's breast without discomfort.
- the hemispheric disk 264 may be comprised of or include an MRI artifact producing material, such as those described above. Since the hemispheric disk 264 is MRI scanned outside of the patient's breast, a stronger artifact may be presented to aid in quickly locating the artifact without obscuring the suspected lesion.
- a localization mechanism 16 is depicted that laterally compresses a downward hanging patient's breast, aspects of the present invention are applicable to other orientations of localization and imaging.
- MRI is discussed herein as the imaging modality for stereotopically guiding the core biopsy
- aspects of the present invention apply to other imaging modalities.
- aspects of the present invention may be used in medical compression devices oriented in other manners, to include standing, lying on one side, or supine.
- aspects of the present invention may be applicable to positioning a biopsy probe through a medial compression plate, or a top and bottom compression plate pair, instead of a lateral compression plate.
- aspects of the present invention are applicable to other diagnostic imaging modalities currently used or that become available in the future.
- aspects of the present invention would have application to diagnostic guided biopsy procedures on other portions of the body, as well as to positioning a probe for utilizing other diagnostic and treatment devices in a minimally invasive manner.
- an elongate needle may be formed without a structural, longitudinal barrier between the vacuum chamber lumen and the cutter lumen.
- the advancing cutter 90 may define a cutter lumen having a circular cross section within a noncircular cross section (e.g., oval) of the internal cavity of the elongate needle.
- a noncircular liner may be used to prevent adhesive entering the undifferentiated internal cavity.
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Surgery (AREA)
- Medical Informatics (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pathology (AREA)
- Molecular Biology (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Magnetic Resonance Imaging Apparatus (AREA)
Priority Applications (7)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US10/170,535 US20030199753A1 (en) | 2002-04-23 | 2002-06-12 | MRI compatible biopsy device with detachable probe |
EP07010108.4A EP1820453B1 (de) | 2002-04-23 | 2003-04-22 | NMR-kompatible Biopsievorrichtung mit abnehmbarer Sonde |
EP03252518A EP1356772B1 (de) | 2002-04-23 | 2003-04-22 | NMR-kompatible Biopsievorrichtung mit abnehmbarer Sonde |
JP2003117378A JP2004033752A (ja) | 2002-04-23 | 2003-04-22 | 取り外し可能なプローブを備えたmri適合性生検装置 |
DE60314037T DE60314037T2 (de) | 2002-04-23 | 2003-04-22 | NMR-kompatible Biopsievorrichtung mit abnehmbarer Sonde |
US12/887,781 US8808198B2 (en) | 2002-04-23 | 2010-09-22 | MRI compatible biopsy device with detachable probe |
US14/446,398 US20140336529A1 (en) | 2002-04-23 | 2014-07-30 | Mri compatible biopsy device with detachable probe |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US37463502P | 2002-04-23 | 2002-04-23 | |
US10/170,535 US20030199753A1 (en) | 2002-04-23 | 2002-06-12 | MRI compatible biopsy device with detachable probe |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US12/887,781 Continuation US8808198B2 (en) | 2002-04-23 | 2010-09-22 | MRI compatible biopsy device with detachable probe |
Publications (1)
Publication Number | Publication Date |
---|---|
US20030199753A1 true US20030199753A1 (en) | 2003-10-23 |
Family
ID=28794031
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US10/170,535 Abandoned US20030199753A1 (en) | 2002-04-23 | 2002-06-12 | MRI compatible biopsy device with detachable probe |
US12/887,781 Expired - Fee Related US8808198B2 (en) | 2002-04-23 | 2010-09-22 | MRI compatible biopsy device with detachable probe |
US14/446,398 Abandoned US20140336529A1 (en) | 2002-04-23 | 2014-07-30 | Mri compatible biopsy device with detachable probe |
Family Applications After (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US12/887,781 Expired - Fee Related US8808198B2 (en) | 2002-04-23 | 2010-09-22 | MRI compatible biopsy device with detachable probe |
US14/446,398 Abandoned US20140336529A1 (en) | 2002-04-23 | 2014-07-30 | Mri compatible biopsy device with detachable probe |
Country Status (4)
Country | Link |
---|---|
US (3) | US20030199753A1 (de) |
EP (1) | EP1356772B1 (de) |
JP (1) | JP2004033752A (de) |
DE (1) | DE60314037T2 (de) |
Cited By (132)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20030199754A1 (en) * | 2002-04-23 | 2003-10-23 | Ethicon Endo-Surgery | Method for using an MRI compatible biopsy device with detachable probe |
US20030199785A1 (en) * | 2002-04-23 | 2003-10-23 | Ethicon Endo-Surgery | Localization mechanism for an MRI compatible biopsy device |
US20040077938A1 (en) * | 2002-10-07 | 2004-04-22 | Mark Joseph L. | Introduction system for minimally invasive surgical instruments |
US20040077972A1 (en) * | 2002-10-18 | 2004-04-22 | Mark Tsonton | Localization mechanism for an MRI compatible biopsy device |
WO2004052179A2 (en) | 2002-12-11 | 2004-06-24 | Ethicon Endo-Surgery, Inc. | Biopsy device with piston advance |
US20050021019A1 (en) * | 2003-07-24 | 2005-01-27 | Dune Medical Devices Ltd. | Method and apparatus for examining a substance, particularly tissue, to characterize its type |
US20050070818A1 (en) * | 2003-09-30 | 2005-03-31 | Mueller Richard L. | Biopsy device with viewing assembly |
US20050080333A1 (en) * | 2003-09-30 | 2005-04-14 | Piron Cameron Anthony | Hybrid imaging method to monitor medical device delivery and patient support for use in the method |
US20050212175A1 (en) * | 2004-03-24 | 2005-09-29 | Mark Tsonton | Method of forming a biopsy device |
US20050215922A1 (en) * | 2004-03-24 | 2005-09-29 | Mark Tsonton | Biopsy device |
EP1598015A1 (de) | 2004-05-21 | 2005-11-23 | Ethicon Endo-Surgery, Inc. | NMR-Biopsievorrichtung mit einer Hülse und einem multifunktionalen Obturator |
EP1642534A2 (de) | 2004-09-29 | 2006-04-05 | Ethicon Endo-Surgery, Inc. | Biopsievorrichtung mit Anordnung zum Aufbewahren von Proben |
US20060074345A1 (en) * | 2004-09-29 | 2006-04-06 | Hibner John A | Biopsy apparatus and method |
EP1665989A2 (de) | 2004-09-29 | 2006-06-07 | Ethicon Endo-Surgery, Inc. | Fluidsteuerung für eine Biopsievorrichtung |
EP1676533A1 (de) | 2004-12-30 | 2006-07-05 | Ethicon Endo-Surgery, Inc. | Verfahren zur Herstellung einer Nadelvorrichtung zur Verwendung mit einem Biopsiegerät |
EP1676532A1 (de) | 2004-12-29 | 2006-07-05 | Ethicon Endo-Surgery, Inc. | Vorrichtung zur Entnahme von Biopsie-Proben mit einem kurzgekuppelten und NMR-kompatiblen Treiber |
US20060155210A1 (en) * | 2005-01-10 | 2006-07-13 | Ethicon Endo-Surgery, Inc. | Biopsy instrument with improved needle penetration |
US20060200042A1 (en) * | 2005-03-04 | 2006-09-07 | Ethicon Endo-Surgery, Inc. | Biopsy device incorporating an adjustable probe sleeve |
US20060200040A1 (en) * | 2005-03-04 | 2006-09-07 | Ethicon Endo-Surgery, Inc. | Biopsy device with variable side aperture |
US20060229528A1 (en) * | 2003-03-29 | 2006-10-12 | C. R. Brad, Inc. | Coaxial cannula provided with a sealing element |
US20060241385A1 (en) * | 2005-04-12 | 2006-10-26 | Ethicon Endo-Surgery, Inc. | Guided disposable fiducial for breast biopsy localization fixture |
US20060239398A1 (en) * | 2005-03-07 | 2006-10-26 | Fused Multimodality Imaging, Ltd. | Breast diagnostic apparatus for fused SPECT, PET, x-ray CT, and optical surface imaging of breast cancer |
US20060251301A1 (en) * | 2004-11-02 | 2006-11-09 | Mcnamara Michael P Jr | Method and apparatus for determining correlation between spatial coordinates in breast |
US20070016003A1 (en) * | 2003-09-30 | 2007-01-18 | Sunnybrook And Women's College Health Sciences Centre | Open architecture imaging apparatus and coil system for magnetic resonance imaging |
US20070032741A1 (en) * | 2005-08-05 | 2007-02-08 | Hibner John A | Biopsy device with replaceable probe and incorporating vibration insertion assist and static vacuum source sample stacking retrieval |
US20070032743A1 (en) * | 2005-08-05 | 2007-02-08 | Hibner John A | Vacuum Syringe Assisted Biopsy Device |
US20070167736A1 (en) * | 2004-05-21 | 2007-07-19 | Dietz Timothy G | MRI biopsy apparatus incorporating an imageable penetrating portion |
US20070179401A1 (en) * | 2006-02-01 | 2007-08-02 | Ethicon Endo-Surgery, Inc. | Biopsy device with replaceable probe incorporating static vacuum source dual valve sample stacking retrieval and saline flush |
US20070185411A1 (en) * | 2006-02-03 | 2007-08-09 | Hibner John A | Biopsy needle and method |
US20070191732A1 (en) * | 2006-02-10 | 2007-08-16 | Voegele James W | Cryogenic probe |
US20070208271A1 (en) * | 2006-03-03 | 2007-09-06 | Voegele James W | Biopsy method |
US20070232953A1 (en) * | 2006-03-31 | 2007-10-04 | Ethicon Endo-Surgery, Inc. | MRI biopsy device |
US20070239064A1 (en) * | 2006-03-29 | 2007-10-11 | Cicenas Chris W | Device for minimally invasive internal tissue removal |
US20070239067A1 (en) * | 2005-08-05 | 2007-10-11 | Hibner John A | Tissue Sample Revolver Drum Biopsy Device |
US20070255168A1 (en) * | 2006-05-01 | 2007-11-01 | Hibner John A | Grid and rotatable cube guide localization fixture for biopsy device |
US20070255169A1 (en) * | 2001-11-19 | 2007-11-01 | Dune Medical Devices Ltd. | Clean margin assessment tool |
US20070255170A1 (en) * | 2006-05-01 | 2007-11-01 | Hibner John A | Biopsy cannula adjustable depth stop |
US20070260267A1 (en) * | 2002-10-07 | 2007-11-08 | Nicoson Zachary R | Localizing obturator |
US20080004545A1 (en) * | 2005-08-05 | 2008-01-03 | Garrison William A | Trigger Fired Radial Plate Specimen Retrieval Biopsy Instrument |
US20080071164A1 (en) * | 2006-07-31 | 2008-03-20 | The Trustees Of Dartmouth College | Devices And Methods For Combined Optical And Magnetic Resonance Imaging |
US20080077005A1 (en) * | 2004-08-12 | 2008-03-27 | Piron Cameron A | System and Method for Multimodality Breast Imaging |
EP1932482A1 (de) | 2006-12-13 | 2008-06-18 | Ethicon Endo-Surgery, Inc. | Biopsieprobenlagerung |
EP1932481A1 (de) | 2006-12-13 | 2008-06-18 | Ethicon Endo-Surgery, Inc. | Biopsiesystem mit Vakuumkontrollmodul |
US20080161720A1 (en) * | 2002-10-07 | 2008-07-03 | Nicoson Zachary R | Registration system |
US20080214953A1 (en) * | 2007-03-01 | 2008-09-04 | Dune Medical Devices Ltd. | Tissue-characterization system and method |
US20080216239A1 (en) * | 2003-09-30 | 2008-09-11 | Christopher Alexander Luginbuhl | Supine patient support for medical imaging |
US20090012388A1 (en) * | 2007-05-03 | 2009-01-08 | Marvel Medtech, Llc | Interventional device |
US20090066664A1 (en) * | 2007-09-07 | 2009-03-12 | Hong Fu Jin Precision Industry (Shenzhen) Co., Ltd. | Touch screen and display method thereof |
US20090131817A1 (en) * | 2007-11-20 | 2009-05-21 | Speeg Trevor W V | Deployment device interface for biopsy device |
US20090149738A1 (en) * | 2007-11-23 | 2009-06-11 | Cameron Anthony Piron | Chest Wall Coil Array for Breast Imaging |
US20090171242A1 (en) * | 2007-12-27 | 2009-07-02 | Hibner John A | Clutch and valving system for tetherless biopsy device |
US20090171218A1 (en) * | 2006-03-24 | 2009-07-02 | Per Ehrenreich Nygaard | Biopsy System |
US20090216110A1 (en) * | 2007-11-23 | 2009-08-27 | Cameron Piron | Open Architecture Tabletop Patient Support and Coil System |
US20090247900A1 (en) * | 2008-03-25 | 2009-10-01 | Brian Zimmer | Push button adjustable spacer |
US20090247901A1 (en) * | 2008-03-25 | 2009-10-01 | Brian Zimmer | Latching side removal spacer |
US20090275858A1 (en) * | 2008-05-02 | 2009-11-05 | Hardin Terry D | Adjustable spacer |
US20100041979A1 (en) * | 2004-05-28 | 2010-02-18 | Harter Raymond D | Interventional immobilization device |
EP1913883A3 (de) * | 2004-05-21 | 2010-02-24 | Ethicon Endo-Surgery, Inc. | Lokalisierungsvorrichtung für eine MRI-Biopsievorrichtung |
US7670299B2 (en) | 2006-03-07 | 2010-03-02 | Ethincon Endo-Surgery, Inc. | Device for minimally invasive internal tissue removal |
US20100106015A1 (en) * | 2008-10-23 | 2010-04-29 | Norris Perry R | Medical device alignment |
US20100106056A1 (en) * | 2008-10-23 | 2010-04-29 | Norris Perry R | Methods for medical device alignment |
US7720532B2 (en) | 2004-03-23 | 2010-05-18 | Dune Medical Ltd. | Clean margin assessment tool |
US20100160811A1 (en) * | 2008-12-18 | 2010-06-24 | Parihar Shailendra K | Z-Stop Feature of Targeting Set for MRI Biopsy Device |
US20100160823A1 (en) * | 2008-12-18 | 2010-06-24 | Parihar Shailendra K | Biopsy Probe and Targeting Set Interface |
US20100160821A1 (en) * | 2008-12-18 | 2010-06-24 | Parihar Shailendra K | Biopsy Device with Sliding Cutter Cover |
US20100160815A1 (en) * | 2008-12-18 | 2010-06-24 | Parihar Shailendra K | Biopsy Device with Retractable Cutter |
US20100160822A1 (en) * | 2008-12-18 | 2010-06-24 | Parihar Shailendra K | Biopsy Device with Detachable Needle |
US20100160810A1 (en) * | 2008-12-18 | 2010-06-24 | Parihar Shailendra K | Multi-Orientation Targeting Set for MRI Biopsy Device |
US20100160825A1 (en) * | 2008-12-18 | 2010-06-24 | Parihar Shailendra K | Targeting Set for MRI Biopsy Device with Probe Holster Support |
US20100160814A1 (en) * | 2008-12-18 | 2010-06-24 | Parihar Shailendra K | Biopsy Device with Telescoping Cutter Cover |
US7806834B2 (en) | 2006-03-07 | 2010-10-05 | Devicor Medical Products, Inc. | Device for minimally invasive internal tissue removal |
US7809425B2 (en) | 2003-07-24 | 2010-10-05 | Dune Medical Devices Ltd. | Method and apparatus for examining a substance, particularly tissue, to characterize its type |
US7806835B2 (en) | 2007-11-20 | 2010-10-05 | Devicor Medical Products, Inc. | Biopsy device with sharps reduction feature |
US20100317991A1 (en) * | 2009-06-16 | 2010-12-16 | Leimbach Jessica P | Biopsy Targeting Cube with Elastomeric Body |
US20100317994A1 (en) * | 2009-06-16 | 2010-12-16 | Leimbach Jessica P | Biopsy Targeting Cube with Living Hinges |
US20100317993A1 (en) * | 2009-06-16 | 2010-12-16 | Leimbach Jessica P | Biopsy Targeting Cube with Angled Interface |
US20100317992A1 (en) * | 2009-06-16 | 2010-12-16 | Leimbach Jessica P | Biopsy Targeting Cube with Malleable Members |
US20100317990A1 (en) * | 2009-06-16 | 2010-12-16 | Leimbach Jessica P | Biopsy Targeting Cube with Elastomeric Edges |
EP2263551A1 (de) | 2009-06-17 | 2010-12-22 | Ethicon Endo-Surgery, Inc. | Wandführung mit MRI-Biopsie-Targeting-Gitter |
EP2263577A2 (de) | 2009-06-17 | 2010-12-22 | Ethicon Endo-Surgery, Inc. | Zylindrische MRI-Biopsie-Targeting-Führung |
EP2263578A2 (de) | 2009-06-17 | 2010-12-22 | Ethicon Endo-Surgery, Inc. | MRI-Biopsie-Targeting-Gitter mit runden Öffnungen |
US7858038B2 (en) | 2007-11-20 | 2010-12-28 | Devicor Medical Products, Inc. | Biopsy device with illuminated tissue holder |
US20110015542A1 (en) * | 2002-04-23 | 2011-01-20 | Devicor Medical Products, Inc. | Mri compatible biopsy device with detachable probe |
US7899515B2 (en) | 2005-03-29 | 2011-03-01 | Dune Medical Devices Ltd. | Electromagnetic sensors for tissue characterization |
US7896817B2 (en) | 2005-08-05 | 2011-03-01 | Devicor Medical Products, Inc. | Biopsy device with manually rotated sample barrel |
US7904145B2 (en) | 2004-03-23 | 2011-03-08 | Dune Medical Devices Ltd. | Clean margin assessment tool |
US20110082364A1 (en) * | 2009-10-05 | 2011-04-07 | Hibner John A | MRI Biopsy Targeting Cube with Retention Wiper |
US20110092850A1 (en) * | 2009-10-16 | 2011-04-21 | Kulkarni Abhijit G | MRI Biopsy Targeting Guide with Rotational Lock |
US20110092847A1 (en) * | 2009-10-16 | 2011-04-21 | Wale Nitin P | MRI Biopsy Targeting Cube with Snap Corners |
US20110092983A1 (en) * | 2009-10-16 | 2011-04-21 | Pawar Ajay D | MRI Biopsy Targeting Cube with Locking Flap |
US20110092849A1 (en) * | 2009-10-16 | 2011-04-21 | Deshmukh Santosh G | MRI Biopsy Targeting Cube with Gripping Arms |
US20110092848A1 (en) * | 2009-10-16 | 2011-04-21 | Hibner John A | MRI Biopsy Targeting Cube with Eccentric Lock |
US7938786B2 (en) | 2006-12-13 | 2011-05-10 | Devicor Medical Products, Inc. | Vacuum timing algorithm for biopsy device |
US7981049B2 (en) | 2006-12-13 | 2011-07-19 | Devicor Medical Products, Inc. | Engagement interface for biopsy system vacuum module |
US20110201965A1 (en) * | 2010-02-18 | 2011-08-18 | John Anthony Hibner | MRI Compatible Biopsy Device |
US8019411B2 (en) | 2002-01-04 | 2011-09-13 | Dune Medical Devices Ltd. | Probes, systems, and methods for examining tissue according to the dielectric properties thereof |
US20110224535A1 (en) * | 2010-03-10 | 2011-09-15 | Martina Doehlemann | Magnetic resonance-assisted biopsy examination method, and a magnetic resonance system for implementing the method |
US8032211B2 (en) | 2002-01-04 | 2011-10-04 | Dune Medical Devices Ltd. | Probes, systems, and methods for examining tissue according to the dielectric properties thereof |
US8052616B2 (en) | 2007-11-20 | 2011-11-08 | Devicor Medical Products, Inc. | Biopsy device with fine pitch drive train |
US8116845B2 (en) | 2005-08-04 | 2012-02-14 | Dune Medical Devices Ltd. | Tissue-characterization probe with effective sensor-to-tissue contact |
US8187204B2 (en) | 2007-10-01 | 2012-05-29 | Suros Surgical Systems, Inc. | Surgical device and method for using same |
US8195282B2 (en) | 2001-11-19 | 2012-06-05 | Dune Medical Devices Ltd | Method and apparatus for examining tissue for predefined target cells, particularly cancerous cells, and a probe useful in such method and apparatus |
US8251916B2 (en) | 2006-12-13 | 2012-08-28 | Devicor Medical Products, Inc. | Revolving tissue sample holder for biopsy device |
US8454531B2 (en) | 2007-11-20 | 2013-06-04 | Devicor Medical Products, Inc. | Icon-based user interface on biopsy system control module |
US8480595B2 (en) | 2006-12-13 | 2013-07-09 | Devicor Medical Products, Inc. | Biopsy device with motorized needle cocking |
US8702623B2 (en) | 2008-12-18 | 2014-04-22 | Devicor Medical Products, Inc. | Biopsy device with discrete tissue chambers |
US8721565B2 (en) | 2005-08-04 | 2014-05-13 | Dune Medical Devices Ltd. | Device for forming an effective sensor-to-tissue contact |
WO2014084961A1 (en) | 2012-10-08 | 2014-06-05 | Devicor Medical Products, Inc. | Tissue biopsy device with thumbwheel and sample holder |
US8747331B2 (en) | 2009-06-23 | 2014-06-10 | Hologic, Inc. | Variable angle guide holder for a biopsy guide plug |
US8808200B2 (en) | 2007-10-01 | 2014-08-19 | Suros Surgical Systems, Inc. | Surgical device and method of using same |
EP2786710A3 (de) * | 2008-04-23 | 2014-10-15 | Devicor Medical Products, Inc. | PEM- und BSGI-Biopsievorrichtungen |
CN104147689A (zh) * | 2014-03-24 | 2014-11-19 | 天津大学 | 核磁图像导航下乳腺穿刺手术机构 |
US9039634B2 (en) | 2007-11-20 | 2015-05-26 | Devicor Medical Products, Inc. | Biopsy device tissue sample holder rotation control |
US9095326B2 (en) | 2006-12-13 | 2015-08-04 | Devicor Medical Products, Inc. | Biopsy system with vacuum control module |
US20150250447A1 (en) * | 2012-11-23 | 2015-09-10 | Kabushiki Kaisha Toshiba | Puncture adapter and ultrasound probe |
US20150250449A1 (en) * | 2012-11-23 | 2015-09-10 | Kabushiki Kaisha Toshiba | Puncture adapter and ultrasound probe |
US20150313471A1 (en) * | 2013-01-24 | 2015-11-05 | University Court Of The University Of St Andrews | Optical apparatus for use with a medical imager |
US9220485B2 (en) | 2010-08-28 | 2015-12-29 | Endochoice, Inc. | Tissue collection and separation device |
US20150374273A1 (en) * | 2008-10-29 | 2015-12-31 | Vasculogic, Llc | Automated vessel puncture device using three-dimensional(3d) near infrared (nir) imaging and a robotically driven needle |
US9332926B2 (en) | 2010-11-25 | 2016-05-10 | Invivo Corporation | MRI imaging probe |
US9392999B2 (en) | 2004-05-21 | 2016-07-19 | Devicor Medical Products, Inc. | MRI biopsy device |
USRE46135E1 (en) | 2005-08-05 | 2016-09-06 | Devicor Medical Products, Inc. | Vacuum syringe assisted biopsy device |
US9646376B2 (en) | 2013-03-15 | 2017-05-09 | Hologic, Inc. | System and method for reviewing and analyzing cytological specimens |
US9750425B2 (en) | 2004-03-23 | 2017-09-05 | Dune Medical Devices Ltd. | Graphical user interfaces (GUI), methods and apparatus for data presentation |
US10595831B2 (en) | 2012-05-30 | 2020-03-24 | Devicor Medical Products, Inc. | Control for biopsy device |
US10786224B2 (en) | 2016-04-21 | 2020-09-29 | Covidien Lp | Biopsy devices and methods of use thereof |
CN112168302A (zh) * | 2020-10-14 | 2021-01-05 | 商晓杰 | 一种心脏彩超定位穿刺装置 |
US10952654B2 (en) | 2017-03-14 | 2021-03-23 | International Business Machines Corporation | PH sensitive surgical tool |
US11179141B2 (en) | 2006-12-13 | 2021-11-23 | Devicor Medical Products, Inc. | Biopsy system |
US11253165B2 (en) | 2019-04-24 | 2022-02-22 | Mohammad Nasser | Intravascular MRI probe assembly |
US11331161B2 (en) | 2018-03-23 | 2022-05-17 | Covidien Lp | Surgical assemblies facilitating tissue marking and methods of use thereof |
US11517294B2 (en) | 2019-05-07 | 2022-12-06 | Covidien Lp | Biopsy devices and methods of use thereof |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE383111T1 (de) * | 2002-08-01 | 2008-01-15 | James E Selis | Biopsievorrichtungen |
US7419472B2 (en) * | 2003-09-30 | 2008-09-02 | Ethicon Endo-Surgery, Inc. | Biopsy instrument with internal specimen collection mechanism |
AU2005244978B2 (en) * | 2004-05-21 | 2011-10-06 | Devicor Medical Products, Inc. | MRI biopsy apparatus incorporating an imagable penetrating portion |
US8075568B2 (en) | 2004-06-11 | 2011-12-13 | Selis James E | Biopsy devices and methods |
US7740594B2 (en) * | 2004-09-29 | 2010-06-22 | Ethicon Endo-Surgery, Inc. | Cutter for biopsy device |
CA3060814C (en) * | 2005-08-10 | 2022-04-19 | C.R. Bard, Inc. | Single-insertion, multiple sample biopsy device with integrated markers |
US8622924B2 (en) | 2008-02-27 | 2014-01-07 | Devicor Medical Products, Inc. | Needle tip for biopsy device |
CA2788976A1 (en) | 2010-02-10 | 2011-08-18 | James Schellenberg | Mr gamma hybrid imaging system |
US9986971B2 (en) | 2013-01-18 | 2018-06-05 | Covidien Lp | Ring laser for use with imaging probe as a safe margin indicator |
WO2015191514A1 (en) * | 2014-06-10 | 2015-12-17 | University Hospitals Of Cleveland | Biopsy tracking systems and methods |
CN105496470B (zh) * | 2016-01-24 | 2018-03-30 | 哈尔滨理工大学 | 一种在核磁环境下手术的乳腺介入机构 |
CN107951547A (zh) * | 2017-12-15 | 2018-04-24 | 李涛 | 一种脊柱外科穿刺辅助器及其使用方法 |
CA3141726A1 (en) * | 2019-06-04 | 2020-12-10 | Great Plains Imaging Llc | Medical instrument for interventional radiology procedure |
CN111281495B (zh) * | 2019-08-12 | 2021-06-18 | 南京医科大学附属逸夫医院 | 一种超声引导穿刺、神经阻滞辅助定位装置 |
WO2021097028A1 (en) * | 2019-11-15 | 2021-05-20 | The Board Of Trustees Of The Leland Stanford Junior University | Clutching mechanism for teleoperated in-bore mri guided biopsies |
Citations (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5211165A (en) * | 1991-09-03 | 1993-05-18 | General Electric Company | Tracking system to follow the position and orientation of a device with radiofrequency field gradients |
US5307808A (en) * | 1992-04-01 | 1994-05-03 | General Electric Company | Tracking system and pulse sequences to monitor the position of a device using magnetic resonance |
US5318025A (en) * | 1992-04-01 | 1994-06-07 | General Electric Company | Tracking system to monitor the position and orientation of a device using multiplexed magnetic resonance detection |
US5437277A (en) * | 1991-11-18 | 1995-08-01 | General Electric Company | Inductively coupled RF tracking system for use in invasive imaging of a living body |
US5443066A (en) * | 1991-11-18 | 1995-08-22 | General Electric Company | Invasive system employing a radiofrequency tracking system |
US5526822A (en) * | 1994-03-24 | 1996-06-18 | Biopsys Medical, Inc. | Method and apparatus for automated biopsy and collection of soft tissue |
US5560373A (en) * | 1994-04-11 | 1996-10-01 | De Santis; Stephen A. | Needle core biopsy instrument with durable or disposable cannula assembly |
US5649547A (en) * | 1994-03-24 | 1997-07-22 | Biopsys Medical, Inc. | Methods and devices for automated biopsy and collection of soft tissue |
US5678549A (en) * | 1992-07-29 | 1997-10-21 | Siemens Aktiengesellschaft | Stereotactic auxiliary attachment for a nuclear magnetic resonance tomography apparatus |
US5830219A (en) * | 1997-02-24 | 1998-11-03 | Trex Medical Corporation | Apparatus for holding and driving a surgical cutting device using stereotactic mammography guidance |
US5855554A (en) * | 1997-03-17 | 1999-01-05 | General Electric Company | Image guided breast lesion localization device |
US5882305A (en) * | 1996-09-09 | 1999-03-16 | General Electric Company | Optical coupling for invasive devices |
US5913863A (en) * | 1997-03-06 | 1999-06-22 | Siemens Aktiengesellschaft | Compression part, and medical compression apparatus employing same |
US6022325A (en) * | 1989-11-21 | 2000-02-08 | Fischer Imaging Corporation | Mammographic biopsy apparatus |
US6036632A (en) * | 1998-05-28 | 2000-03-14 | Barzell-Whitmore Maroon Bells, Inc. | Sterile disposable template grid system |
US6077230A (en) * | 1998-05-14 | 2000-06-20 | Ethicon Endo-Surgery, Inc. | Biopsy instrument with removable extractor |
US6142955A (en) * | 1997-09-19 | 2000-11-07 | United States Surgical Corporation | Biopsy apparatus and method |
US6174291B1 (en) * | 1998-03-09 | 2001-01-16 | Spectrascience, Inc. | Optical biopsy system and methods for tissue diagnosis |
US6193673B1 (en) * | 1998-02-20 | 2001-02-27 | United States Surgical Corporation | Biopsy instrument driver apparatus |
US6261241B1 (en) * | 1998-03-03 | 2001-07-17 | Senorx, Inc. | Electrosurgical biopsy device and method |
US6270506B1 (en) * | 1998-07-31 | 2001-08-07 | Siemens Aktiengesellschaft | Medical targeting apparatus |
US6289233B1 (en) * | 1998-11-25 | 2001-09-11 | General Electric Company | High speed tracking of interventional devices using an MRI system |
US20030199785A1 (en) * | 2002-04-23 | 2003-10-23 | Ethicon Endo-Surgery | Localization mechanism for an MRI compatible biopsy device |
US6758824B1 (en) * | 2000-11-06 | 2004-07-06 | Suros Surgical Systems, Inc. | Biopsy apparatus |
US20050027210A1 (en) * | 2000-11-06 | 2005-02-03 | Miller Michael E. | Biopsy apparatus |
Family Cites Families (29)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2922420A (en) * | 1957-11-29 | 1960-01-26 | Sierra Eng Co | Epidural needle |
FR2332743A1 (fr) * | 1975-11-28 | 1977-06-24 | Inst Nat Sante Rech Med | Sondes et appareils de biopsie cerebrale |
US4163446A (en) * | 1978-01-31 | 1979-08-07 | Khosrow Jamshidi | Biopsy needle and removable pad therefor |
GB8818162D0 (en) * | 1988-07-29 | 1988-09-01 | Olliffe R M | Hypodermic syringe |
US6032673A (en) * | 1994-10-13 | 2000-03-07 | Femrx, Inc. | Methods and devices for tissue removal |
US5601583A (en) * | 1995-02-15 | 1997-02-11 | Smith & Nephew Endoscopy Inc. | Surgical instrument |
US5715822A (en) * | 1995-09-28 | 1998-02-10 | General Electric Company | Magnetic resonance devices suitable for both tracking and imaging |
US5782764A (en) * | 1995-11-07 | 1998-07-21 | Iti Medical Technologies, Inc. | Fiber composite invasive medical instruments and methods for use in interventional imaging procedures |
US5776062A (en) * | 1996-10-15 | 1998-07-07 | Fischer Imaging Corporation | Enhanced breast imaging/biopsy system employing targeted ultrasound |
US6119033A (en) * | 1997-03-04 | 2000-09-12 | Biotrack, Inc. | Method of monitoring a location of an area of interest within a patient during a medical procedure |
US6383145B1 (en) * | 1997-09-12 | 2002-05-07 | Imagyn Medical Technologies California, Inc. | Incisional breast biopsy device |
US20010045575A1 (en) * | 1998-05-01 | 2001-11-29 | Mark Ashby | Device and method for facilitating hemostasis of a biopsy tract |
US6007497A (en) * | 1998-06-30 | 1999-12-28 | Ethicon Endo-Surgery, Inc. | Surgical biopsy device |
US6063037A (en) * | 1998-08-21 | 2000-05-16 | Manan Medical Products, Inc. | Bone marrow biopsy needle |
CA2287087C (en) * | 1998-10-23 | 2007-12-04 | Ethicon Endo-Surgery, Inc. | Surgical device for the collection of soft tissue |
WO2000051484A2 (en) * | 1998-11-25 | 2000-09-08 | Fischer Imaging Corporation | User interface system for mammographic imager |
US6086544A (en) * | 1999-03-31 | 2000-07-11 | Ethicon Endo-Surgery, Inc. | Control apparatus for an automated surgical biopsy device |
US6675037B1 (en) * | 1999-09-29 | 2004-01-06 | Regents Of The University Of Minnesota | MRI-guided interventional mammary procedures |
US6261299B1 (en) * | 1999-11-26 | 2001-07-17 | The Ohio State University | Stereotactic apparatus and methods |
US6241687B1 (en) * | 2000-02-18 | 2001-06-05 | Ethicon Endo-Surgery, Inc. | Method of use for a biopsy instrument with breakable sample segments |
US6889073B2 (en) * | 2000-05-08 | 2005-05-03 | David A. Lampman | Breast biopsy and therapy system for magnetic resonance imagers |
WO2002013709A1 (de) | 2000-08-01 | 2002-02-21 | Oliver Wendt | Einrichtung zur navigation und positionierung von medizinischen instrumenten in magnetresonanztomographen |
US6602203B2 (en) * | 2000-10-13 | 2003-08-05 | Ethicon Endo-Surgery, Inc. | Remote thumbwheel for a surgical biopsy device |
US6626849B2 (en) * | 2001-11-01 | 2003-09-30 | Ethicon Endo-Surgery, Inc. | MRI compatible surgical biopsy device |
US7192404B2 (en) * | 2001-12-12 | 2007-03-20 | Ethicon Endo-Surgery, Inc. | MRI compatible surgical biopsy device having a tip which leaves an artifact |
US7769426B2 (en) * | 2002-04-23 | 2010-08-03 | Ethicon Endo-Surgery, Inc. | Method for using an MRI compatible biopsy device with detachable probe |
US20030199753A1 (en) * | 2002-04-23 | 2003-10-23 | Ethicon Endo-Surgery | MRI compatible biopsy device with detachable probe |
US7379769B2 (en) * | 2003-09-30 | 2008-05-27 | Sunnybrook Health Sciences Center | Hybrid imaging method to monitor medical device delivery and patient support for use in the method |
US7708751B2 (en) | 2004-05-21 | 2010-05-04 | Ethicon Endo-Surgery, Inc. | MRI biopsy device |
-
2002
- 2002-06-12 US US10/170,535 patent/US20030199753A1/en not_active Abandoned
-
2003
- 2003-04-22 EP EP03252518A patent/EP1356772B1/de not_active Expired - Fee Related
- 2003-04-22 DE DE60314037T patent/DE60314037T2/de not_active Expired - Lifetime
- 2003-04-22 JP JP2003117378A patent/JP2004033752A/ja active Pending
-
2010
- 2010-09-22 US US12/887,781 patent/US8808198B2/en not_active Expired - Fee Related
-
2014
- 2014-07-30 US US14/446,398 patent/US20140336529A1/en not_active Abandoned
Patent Citations (27)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6022325A (en) * | 1989-11-21 | 2000-02-08 | Fischer Imaging Corporation | Mammographic biopsy apparatus |
US5211165A (en) * | 1991-09-03 | 1993-05-18 | General Electric Company | Tracking system to follow the position and orientation of a device with radiofrequency field gradients |
US5437277A (en) * | 1991-11-18 | 1995-08-01 | General Electric Company | Inductively coupled RF tracking system for use in invasive imaging of a living body |
US5443066A (en) * | 1991-11-18 | 1995-08-22 | General Electric Company | Invasive system employing a radiofrequency tracking system |
US5445150A (en) * | 1991-11-18 | 1995-08-29 | General Electric Company | Invasive system employing a radiofrequency tracking system |
US5307808A (en) * | 1992-04-01 | 1994-05-03 | General Electric Company | Tracking system and pulse sequences to monitor the position of a device using magnetic resonance |
US5318025A (en) * | 1992-04-01 | 1994-06-07 | General Electric Company | Tracking system to monitor the position and orientation of a device using multiplexed magnetic resonance detection |
US5678549A (en) * | 1992-07-29 | 1997-10-21 | Siemens Aktiengesellschaft | Stereotactic auxiliary attachment for a nuclear magnetic resonance tomography apparatus |
US5649547A (en) * | 1994-03-24 | 1997-07-22 | Biopsys Medical, Inc. | Methods and devices for automated biopsy and collection of soft tissue |
US5775333A (en) * | 1994-03-24 | 1998-07-07 | Ethicon Endo-Surgery, Inc. | Apparatus for automated biopsy and collection of soft tissue |
US5526822A (en) * | 1994-03-24 | 1996-06-18 | Biopsys Medical, Inc. | Method and apparatus for automated biopsy and collection of soft tissue |
US5560373A (en) * | 1994-04-11 | 1996-10-01 | De Santis; Stephen A. | Needle core biopsy instrument with durable or disposable cannula assembly |
US5882305A (en) * | 1996-09-09 | 1999-03-16 | General Electric Company | Optical coupling for invasive devices |
US5830219A (en) * | 1997-02-24 | 1998-11-03 | Trex Medical Corporation | Apparatus for holding and driving a surgical cutting device using stereotactic mammography guidance |
US5913863A (en) * | 1997-03-06 | 1999-06-22 | Siemens Aktiengesellschaft | Compression part, and medical compression apparatus employing same |
US5855554A (en) * | 1997-03-17 | 1999-01-05 | General Electric Company | Image guided breast lesion localization device |
US6142955A (en) * | 1997-09-19 | 2000-11-07 | United States Surgical Corporation | Biopsy apparatus and method |
US6193673B1 (en) * | 1998-02-20 | 2001-02-27 | United States Surgical Corporation | Biopsy instrument driver apparatus |
US6261241B1 (en) * | 1998-03-03 | 2001-07-17 | Senorx, Inc. | Electrosurgical biopsy device and method |
US6174291B1 (en) * | 1998-03-09 | 2001-01-16 | Spectrascience, Inc. | Optical biopsy system and methods for tissue diagnosis |
US6077230A (en) * | 1998-05-14 | 2000-06-20 | Ethicon Endo-Surgery, Inc. | Biopsy instrument with removable extractor |
US6036632A (en) * | 1998-05-28 | 2000-03-14 | Barzell-Whitmore Maroon Bells, Inc. | Sterile disposable template grid system |
US6270506B1 (en) * | 1998-07-31 | 2001-08-07 | Siemens Aktiengesellschaft | Medical targeting apparatus |
US6289233B1 (en) * | 1998-11-25 | 2001-09-11 | General Electric Company | High speed tracking of interventional devices using an MRI system |
US6758824B1 (en) * | 2000-11-06 | 2004-07-06 | Suros Surgical Systems, Inc. | Biopsy apparatus |
US20050027210A1 (en) * | 2000-11-06 | 2005-02-03 | Miller Michael E. | Biopsy apparatus |
US20030199785A1 (en) * | 2002-04-23 | 2003-10-23 | Ethicon Endo-Surgery | Localization mechanism for an MRI compatible biopsy device |
Cited By (306)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9226979B2 (en) | 2001-11-19 | 2016-01-05 | Dune Medical Devices Ltd. | Method and apparatus for examining tissue for predefined target cells, particularly cancerous cells, and a probe useful in such method and apparatus |
US8195282B2 (en) | 2001-11-19 | 2012-06-05 | Dune Medical Devices Ltd | Method and apparatus for examining tissue for predefined target cells, particularly cancerous cells, and a probe useful in such method and apparatus |
US20070255169A1 (en) * | 2001-11-19 | 2007-11-01 | Dune Medical Devices Ltd. | Clean margin assessment tool |
US8032211B2 (en) | 2002-01-04 | 2011-10-04 | Dune Medical Devices Ltd. | Probes, systems, and methods for examining tissue according to the dielectric properties thereof |
US8019411B2 (en) | 2002-01-04 | 2011-09-13 | Dune Medical Devices Ltd. | Probes, systems, and methods for examining tissue according to the dielectric properties thereof |
US8808198B2 (en) | 2002-04-23 | 2014-08-19 | Devicor Medical Products, Inc. | MRI compatible biopsy device with detachable probe |
US20030199785A1 (en) * | 2002-04-23 | 2003-10-23 | Ethicon Endo-Surgery | Localization mechanism for an MRI compatible biopsy device |
US20110015542A1 (en) * | 2002-04-23 | 2011-01-20 | Devicor Medical Products, Inc. | Mri compatible biopsy device with detachable probe |
US7769426B2 (en) | 2002-04-23 | 2010-08-03 | Ethicon Endo-Surgery, Inc. | Method for using an MRI compatible biopsy device with detachable probe |
US7826883B2 (en) * | 2002-04-23 | 2010-11-02 | Devicor Medical Products, Inc. | Localization mechanism for an MRI compatible biopsy device |
US20030199754A1 (en) * | 2002-04-23 | 2003-10-23 | Ethicon Endo-Surgery | Method for using an MRI compatible biopsy device with detachable probe |
US7347829B2 (en) | 2002-10-07 | 2008-03-25 | Suros Surgical Systems, Inc. | Introduction system for minimally invasive surgical instruments |
US20040077938A1 (en) * | 2002-10-07 | 2004-04-22 | Mark Joseph L. | Introduction system for minimally invasive surgical instruments |
US20070260267A1 (en) * | 2002-10-07 | 2007-11-08 | Nicoson Zachary R | Localizing obturator |
US20080161720A1 (en) * | 2002-10-07 | 2008-07-03 | Nicoson Zachary R | Registration system |
US20040077972A1 (en) * | 2002-10-18 | 2004-04-22 | Mark Tsonton | Localization mechanism for an MRI compatible biopsy device |
US7438692B2 (en) * | 2002-10-18 | 2008-10-21 | Mark Tsonton | Localization mechanism for an MRI compatible biopsy device |
US7727164B2 (en) | 2002-12-11 | 2010-06-01 | Ethicon Endo-Surgery, Inc. | Method for operating a biopsy device |
US20050101880A1 (en) * | 2002-12-11 | 2005-05-12 | Chris Cicenas | Biopsy device with piston advance |
WO2004052179A2 (en) | 2002-12-11 | 2004-06-24 | Ethicon Endo-Surgery, Inc. | Biopsy device with piston advance |
US20100063416A1 (en) * | 2002-12-11 | 2010-03-11 | Chris Cicenas | Biopsy Device and Method |
US20080103413A1 (en) * | 2002-12-11 | 2008-05-01 | Chris Cicenas | Method for operating a biopsy device |
US7351210B2 (en) | 2002-12-11 | 2008-04-01 | Ethicon-Endo-Surgery, Inc. | Biopsy device with piston advance |
US8845547B2 (en) | 2003-03-29 | 2014-09-30 | C. R. Bard, Inc. | Cannula provided with a sealing element for use in a medical procedure |
US7740598B2 (en) | 2003-03-29 | 2010-06-22 | C. R. Bard, Inc. | Coaxial cannula provided with a sealing element |
US11071529B2 (en) | 2003-03-29 | 2021-07-27 | C.R. Bard, Inc. | Cannula provided with a sealing element for use in a medical procedure |
US20060229528A1 (en) * | 2003-03-29 | 2006-10-12 | C. R. Brad, Inc. | Coaxial cannula provided with a sealing element |
US9706980B2 (en) * | 2003-03-29 | 2017-07-18 | C. R. Bard, Inc. | Cannula provided with a sealing element for use in a medical procedure |
US7645239B2 (en) * | 2003-03-29 | 2010-01-12 | C. R. Bard, Inc. | Coaxial cannula provided with a sealing element |
US20150005664A1 (en) * | 2003-03-29 | 2015-01-01 | C. R. Bard, Inc. | Cannula provided with a sealing element for use in a medical procedure |
US9980706B2 (en) | 2003-03-29 | 2018-05-29 | C. R. Bard, Inc. | Cannula provided with a sealing element for use in a medical procedure |
US7082325B2 (en) * | 2003-07-24 | 2006-07-25 | Dune Medical Devices Ltd. | Method and apparatus for examining a substance, particularly tissue, to characterize its type |
WO2005009200A3 (en) * | 2003-07-24 | 2005-08-04 | Dune Medical Devices Ltd | Method and apparatus for examining a substance,particularly tissue, to characterize its type |
US7809425B2 (en) | 2003-07-24 | 2010-10-05 | Dune Medical Devices Ltd. | Method and apparatus for examining a substance, particularly tissue, to characterize its type |
US20050021019A1 (en) * | 2003-07-24 | 2005-01-27 | Dune Medical Devices Ltd. | Method and apparatus for examining a substance, particularly tissue, to characterize its type |
US9241765B2 (en) | 2003-09-30 | 2016-01-26 | Invivo Corporation | Open architecture imaging apparatus and coil system for magnetic resonance imaging |
US7379769B2 (en) * | 2003-09-30 | 2008-05-27 | Sunnybrook Health Sciences Center | Hybrid imaging method to monitor medical device delivery and patient support for use in the method |
US7970452B2 (en) | 2003-09-30 | 2011-06-28 | Hologic, Inc. | Open architecture imaging apparatus and coil system for magnetic resonance imaging |
US20080306377A1 (en) * | 2003-09-30 | 2008-12-11 | Cameron Anthony Piron | Open architecture imaging apparatus and coil system for magnetic resonance imaging |
US7937132B2 (en) | 2003-09-30 | 2011-05-03 | Sunnybrook Health Sciences Center | Hybrid imaging method to monitor medical device delivery and patient support for use in method |
US8050736B2 (en) | 2003-09-30 | 2011-11-01 | Hologic, Inc. | Hybrid imaging method to monitor medical device delivery and patient support for use in the method |
US7908690B2 (en) | 2003-09-30 | 2011-03-22 | Sentinelle Medical, Inc. | Supine patient support for medical imaging |
US20050070818A1 (en) * | 2003-09-30 | 2005-03-31 | Mueller Richard L. | Biopsy device with viewing assembly |
US20080255443A1 (en) * | 2003-09-30 | 2008-10-16 | Cameron Anthony Piron | Hybrid imaging method to monitor medical device delivery and patient support for use in the method |
US20080216239A1 (en) * | 2003-09-30 | 2008-09-11 | Christopher Alexander Luginbuhl | Supine patient support for medical imaging |
US20070016003A1 (en) * | 2003-09-30 | 2007-01-18 | Sunnybrook And Women's College Health Sciences Centre | Open architecture imaging apparatus and coil system for magnetic resonance imaging |
US20050080333A1 (en) * | 2003-09-30 | 2005-04-14 | Piron Cameron Anthony | Hybrid imaging method to monitor medical device delivery and patient support for use in the method |
US20080132785A1 (en) * | 2003-09-30 | 2008-06-05 | Cameron Anthony Piron | Hybrid imaging method to monitor medical device delivery and patient support for use in method |
US8571632B2 (en) | 2003-09-30 | 2013-10-29 | Hologic, Inc. | Open architecture imaging apparatus and coil system for magnetic resonance imaging |
US7720532B2 (en) | 2004-03-23 | 2010-05-18 | Dune Medical Ltd. | Clean margin assessment tool |
US11179053B2 (en) | 2004-03-23 | 2021-11-23 | Dilon Medical Technologies Ltd. | Graphical user interfaces (GUI), methods and apparatus for data presentation |
US9750425B2 (en) | 2004-03-23 | 2017-09-05 | Dune Medical Devices Ltd. | Graphical user interfaces (GUI), methods and apparatus for data presentation |
US7904145B2 (en) | 2004-03-23 | 2011-03-08 | Dune Medical Devices Ltd. | Clean margin assessment tool |
US9345456B2 (en) | 2004-03-24 | 2016-05-24 | Devicor Medical Products, Inc. | Biopsy device |
US7445739B2 (en) | 2004-03-24 | 2008-11-04 | Ethicon Endo-Surgery, Inc. | Method of forming a biopsy device |
US20050215922A1 (en) * | 2004-03-24 | 2005-09-29 | Mark Tsonton | Biopsy device |
US20050212175A1 (en) * | 2004-03-24 | 2005-09-29 | Mark Tsonton | Method of forming a biopsy device |
US20090281453A1 (en) * | 2004-05-21 | 2009-11-12 | Ethicon Endo-Surgery, Inc. | MRI Biopsy Apparatus Incorporating a Sleeve and Multi-Function Obturator |
US20070167736A1 (en) * | 2004-05-21 | 2007-07-19 | Dietz Timothy G | MRI biopsy apparatus incorporating an imageable penetrating portion |
US9638770B2 (en) | 2004-05-21 | 2017-05-02 | Devicor Medical Products, Inc. | MRI biopsy apparatus incorporating an imageable penetrating portion |
US7862517B2 (en) | 2004-05-21 | 2011-01-04 | Devicor Medical Products, Inc. | MRI biopsy device |
EP1598015A1 (de) | 2004-05-21 | 2005-11-23 | Ethicon Endo-Surgery, Inc. | NMR-Biopsievorrichtung mit einer Hülse und einem multifunktionalen Obturator |
US20050261581A1 (en) * | 2004-05-21 | 2005-11-24 | Hughes Robert J | MRI biopsy device |
US20050277829A1 (en) * | 2004-05-21 | 2005-12-15 | Mark Tsonton | Mri biopsy apparatus incorporating a sleeve and multi-function obturator |
US9392999B2 (en) | 2004-05-21 | 2016-07-19 | Devicor Medical Products, Inc. | MRI biopsy device |
US20050283069A1 (en) * | 2004-05-21 | 2005-12-22 | Hughes Robert J | MRI biopsy device localization fixture |
US9795365B2 (en) | 2004-05-21 | 2017-10-24 | Devicor Medical Products, Inc. | MRI biopsy apparatus incorporating a sleeve and multi-function obturator |
US20070038144A1 (en) * | 2004-05-21 | 2007-02-15 | Hughes Robert J | MRI Biopsy Device Localization Fixture |
US7708751B2 (en) | 2004-05-21 | 2010-05-04 | Ethicon Endo-Surgery, Inc. | MRI biopsy device |
US7711407B2 (en) | 2004-05-21 | 2010-05-04 | Ethicon Endo-Surgery, Inc. | MRI biopsy device localization fixture |
US7831290B2 (en) | 2004-05-21 | 2010-11-09 | Devicor Medical Products, Inc. | MRI biopsy device localization fixture |
US7693567B2 (en) | 2004-05-21 | 2010-04-06 | Ethicon Endo-Surgery, Inc. | MRI biopsy apparatus incorporating a sleeve and multi-function obturator |
EP1913883A3 (de) * | 2004-05-21 | 2010-02-24 | Ethicon Endo-Surgery, Inc. | Lokalisierungsvorrichtung für eine MRI-Biopsievorrichtung |
US9504453B2 (en) | 2004-05-21 | 2016-11-29 | Devicor Medical Products, Inc. | MRI biopsy device |
US20100041979A1 (en) * | 2004-05-28 | 2010-02-18 | Harter Raymond D | Interventional immobilization device |
US20080077005A1 (en) * | 2004-08-12 | 2008-03-27 | Piron Cameron A | System and Method for Multimodality Breast Imaging |
US9468425B2 (en) | 2004-09-29 | 2016-10-18 | Devicor Medical Products, Inc. | Biopsy device with integral vacuum assist and tissue sample and fluid capturing canister |
EP1642534A2 (de) | 2004-09-29 | 2006-04-05 | Ethicon Endo-Surgery, Inc. | Biopsievorrichtung mit Anordnung zum Aufbewahren von Proben |
US9757100B2 (en) | 2004-09-29 | 2017-09-12 | Devicor Medical Products, Inc. | Biopsy device with integral vacuum assist and tissue sample and fluid capturing canister |
US7758515B2 (en) | 2004-09-29 | 2010-07-20 | Ethicon Endo-Surgery, Inc. | Biopsy device with integral vacuum assist and tissue sample and fluid capturing canister |
US20100222700A1 (en) * | 2004-09-29 | 2010-09-02 | Hibner John A | BIOPSY Device With Sample Storage |
US7753857B2 (en) | 2004-09-29 | 2010-07-13 | Ethicon Endo-Surgery, Inc. | Tissue sample serial capturing biopsy device |
US20100228146A1 (en) * | 2004-09-29 | 2010-09-09 | Hibner John A | Biopsy Device With Integral vacuum Assist And Tissue Sample And Fluid Capturing Canister |
US20070255173A1 (en) * | 2004-09-29 | 2007-11-01 | Ethicon Endo-Surgery, Inc. | Biopsy Device with Integral Vacuum Assist and Tissue Sample and Fluid Capturing Canister |
US20070255174A1 (en) * | 2004-09-29 | 2007-11-01 | Ethicon Endo-Surgery, Inc. | Tissue Sample Serial Capturing Biopsy Device |
US9265485B2 (en) | 2004-09-29 | 2016-02-23 | Devicor Medical Products, Inc. | Biopsy device with integral vacuum assist and tissue sample and fluid capturing canister |
US20060074345A1 (en) * | 2004-09-29 | 2006-04-06 | Hibner John A | Biopsy apparatus and method |
US20130226027A1 (en) * | 2004-09-29 | 2013-08-29 | Devicor Medical Products, Inc. | Biopsy Device with Sample Storage |
EP1665989A2 (de) | 2004-09-29 | 2006-06-07 | Ethicon Endo-Surgery, Inc. | Fluidsteuerung für eine Biopsievorrichtung |
US20130066231A1 (en) * | 2004-09-29 | 2013-03-14 | Devicor Medical Products, Inc. | Biopsy Device with Sample Storage |
US8956306B2 (en) | 2004-09-29 | 2015-02-17 | Devicor Medical Products, Inc. | Biopsy device with integral vacuum assist and tissue sample and fluid capturing canister |
US9901325B2 (en) * | 2004-09-29 | 2018-02-27 | Devicor Medical Products, Inc. | Biopsy device with sample storage |
US8491496B2 (en) | 2004-09-29 | 2013-07-23 | Devicor Medical Products, Inc. | Biopsy device with sample storage |
US20060251301A1 (en) * | 2004-11-02 | 2006-11-09 | Mcnamara Michael P Jr | Method and apparatus for determining correlation between spatial coordinates in breast |
US7611474B2 (en) | 2004-12-29 | 2009-11-03 | Ethicon Endo-Surgery, Inc. | Core sampling biopsy device with short coupled MRI-compatible driver |
US20100049086A1 (en) * | 2004-12-29 | 2010-02-25 | Hibner John A | Biopsy Device |
US20060149163A1 (en) * | 2004-12-29 | 2006-07-06 | Hibner John A | Core sampling biopsy device with short coupled MRI-compatible driver |
EP1676532A1 (de) | 2004-12-29 | 2006-07-05 | Ethicon Endo-Surgery, Inc. | Vorrichtung zur Entnahme von Biopsie-Proben mit einem kurzgekuppelten und NMR-kompatiblen Treiber |
US20060144548A1 (en) * | 2004-12-30 | 2006-07-06 | Beckman Andrew T | Method of manufacturing a needle assembly for use with a biopsy device |
US7895725B2 (en) | 2004-12-30 | 2011-03-01 | Devicor Medical Products, Inc. | Method of manufacturing a needle assembly for use with a biopsy device |
US9044214B2 (en) | 2004-12-30 | 2015-06-02 | Devicor Medical Products, Inc. | Needle assembly for use with a biopsy device |
US20110112437A1 (en) * | 2004-12-30 | 2011-05-12 | Devicor Medical Products, Inc. | Needle assembly for use with a biopsy device |
EP1676533A1 (de) | 2004-12-30 | 2006-07-05 | Ethicon Endo-Surgery, Inc. | Verfahren zur Herstellung einer Nadelvorrichtung zur Verwendung mit einem Biopsiegerät |
US20090260755A1 (en) * | 2004-12-30 | 2009-10-22 | Ethicon Endo-Surgery, Inc. | Method of manufacturing a needle assembly for use with a biopsy device |
US8622928B2 (en) | 2004-12-30 | 2014-01-07 | Devicor Medical Products, Inc. | Needle assembly for use with a biopsy device |
US7470237B2 (en) | 2005-01-10 | 2008-12-30 | Ethicon Endo-Surgery, Inc. | Biopsy instrument with improved needle penetration |
US20060155210A1 (en) * | 2005-01-10 | 2006-07-13 | Ethicon Endo-Surgery, Inc. | Biopsy instrument with improved needle penetration |
US20060200042A1 (en) * | 2005-03-04 | 2006-09-07 | Ethicon Endo-Surgery, Inc. | Biopsy device incorporating an adjustable probe sleeve |
US7517322B2 (en) | 2005-03-04 | 2009-04-14 | Ethicon Endo-Surgery, Inc. | Biopsy device with variable side aperture |
US8287466B2 (en) | 2005-03-04 | 2012-10-16 | Devicor Medical Products, Inc. | Biopsy device with variable side aperture |
US20060200041A1 (en) * | 2005-03-04 | 2006-09-07 | Ethicon Endo-Surgery, Inc. | Biopsy device incorporating an adjustable probe sleeve |
US7717861B2 (en) * | 2005-03-04 | 2010-05-18 | Ethicon Endo-Surgery, Inc. | Biopsy device with variable side aperture |
US20080114264A1 (en) * | 2005-03-04 | 2008-05-15 | Ethicon Endo-Surgery, Inc. | Biopsy Device With Variable Side Aperture |
US9095327B2 (en) | 2005-03-04 | 2015-08-04 | Devicor Medical Products, Inc. | Biopsy device with variable side aperture |
US7481775B2 (en) | 2005-03-04 | 2009-01-27 | Ethicon Endo-Surgery, Inc. | Biopsy device incorporating an adjustable probe sleeve |
US9668717B2 (en) | 2005-03-04 | 2017-06-06 | Devicor Medical Products, Inc. | Biopsy device with variable side aperture |
US20060200040A1 (en) * | 2005-03-04 | 2006-09-07 | Ethicon Endo-Surgery, Inc. | Biopsy device with variable side aperture |
US20060239398A1 (en) * | 2005-03-07 | 2006-10-26 | Fused Multimodality Imaging, Ltd. | Breast diagnostic apparatus for fused SPECT, PET, x-ray CT, and optical surface imaging of breast cancer |
US7899515B2 (en) | 2005-03-29 | 2011-03-01 | Dune Medical Devices Ltd. | Electromagnetic sensors for tissue characterization |
US20060241385A1 (en) * | 2005-04-12 | 2006-10-26 | Ethicon Endo-Surgery, Inc. | Guided disposable fiducial for breast biopsy localization fixture |
US9526460B2 (en) | 2005-08-04 | 2016-12-27 | Dune Medical Devices Ltd. | Tissue-characterization probe with effective sensor-to-tissue contact |
US8721565B2 (en) | 2005-08-04 | 2014-05-13 | Dune Medical Devices Ltd. | Device for forming an effective sensor-to-tissue contact |
US8116845B2 (en) | 2005-08-04 | 2012-02-14 | Dune Medical Devices Ltd. | Tissue-characterization probe with effective sensor-to-tissue contact |
US9968339B2 (en) | 2005-08-05 | 2018-05-15 | Devicor Medical Products, Inc. | Biopsy device with rotatable tissue sample holder |
US20150141867A1 (en) * | 2005-08-05 | 2015-05-21 | Devicor Medical Products, Inc. | Biopsy device with translating valve member |
US20100113971A1 (en) * | 2005-08-05 | 2010-05-06 | Ethicon Endo-Surgery, Inc. | Biopsy Device with Translating Valve Mechanism |
US8979769B2 (en) | 2005-08-05 | 2015-03-17 | Devicor Medical Products, Inc. | Biopsy device with vacuum assisted bleeding control |
US20100113973A1 (en) * | 2005-08-05 | 2010-05-06 | Ethicon Endo-Surgery, Inc. | Biopsy Device with Rotatable Tissue Sample Holder |
US9414814B2 (en) | 2005-08-05 | 2016-08-16 | Devicor Medical Products, Inc. | Biopsy device with rotatable tissue sample holder |
US7828748B2 (en) | 2005-08-05 | 2010-11-09 | Devicor Medical Products, Inc. | Vacuum syringe assisted biopsy device |
US20070032741A1 (en) * | 2005-08-05 | 2007-02-08 | Hibner John A | Biopsy device with replaceable probe and incorporating vibration insertion assist and static vacuum source sample stacking retrieval |
USRE46135E1 (en) | 2005-08-05 | 2016-09-06 | Devicor Medical Products, Inc. | Vacuum syringe assisted biopsy device |
US8241226B2 (en) | 2005-08-05 | 2012-08-14 | Devicor Medical Products, Inc. | Biopsy device with rotatable tissue sample holder |
US8911381B2 (en) | 2005-08-05 | 2014-12-16 | Devicor Medical Products, Inc. | Biopsy device with translating valve member |
US8905943B2 (en) | 2005-08-05 | 2014-12-09 | Devicor Medical Products, Inc. | Biopsy device with rotatable tissue sample holder |
US20110144532A1 (en) * | 2005-08-05 | 2011-06-16 | Devicor Medical Products, Inc. | Biopsy device with vacuum assisted bleeding control |
US20070032742A1 (en) * | 2005-08-05 | 2007-02-08 | Monson Gavin M | Biopsy Device with Vacuum Assisted Bleeding Control |
US7854707B2 (en) | 2005-08-05 | 2010-12-21 | Devicor Medical Products, Inc. | Tissue sample revolver drum biopsy device |
US20070239067A1 (en) * | 2005-08-05 | 2007-10-11 | Hibner John A | Tissue Sample Revolver Drum Biopsy Device |
US8038627B2 (en) | 2005-08-05 | 2011-10-18 | Devicor Medical Products, Inc. | Biopsy device with translating valve mechanism |
US7918804B2 (en) | 2005-08-05 | 2011-04-05 | Devicor Medical Products, Inc. | Biopsy device with vacuum assisted bleeding control |
US8568335B2 (en) | 2005-08-05 | 2013-10-29 | Devicor Medical Products, Inc. | Biopsy device with vacuum assisted bleeding control |
US9901327B2 (en) * | 2005-08-05 | 2018-02-27 | Devicor Medical Products, Inc. | Biopsy device with translating valve member |
US20110071433A1 (en) * | 2005-08-05 | 2011-03-24 | Devicor Medical Products, Inc. | Biopsy device with translating valve member |
US9907542B2 (en) | 2005-08-05 | 2018-03-06 | Devicor Medical Products, Inc. | Biopsy device with translating valve member |
US8235913B2 (en) | 2005-08-05 | 2012-08-07 | Devicor Medical Products, Inc. | Biopsy device with translating valve member |
US20070032743A1 (en) * | 2005-08-05 | 2007-02-08 | Hibner John A | Vacuum Syringe Assisted Biopsy Device |
US7896817B2 (en) | 2005-08-05 | 2011-03-01 | Devicor Medical Products, Inc. | Biopsy device with manually rotated sample barrel |
EP3326539A1 (de) | 2005-08-05 | 2018-05-30 | Devicor Medical Products, Inc. | Biopsievorrichtung |
EP2455000A1 (de) | 2005-08-05 | 2012-05-23 | Devicor Medical Products, Inc. | Biopsievorrichtung mit verschiebbarem Ventilelement |
US9005136B2 (en) | 2005-08-05 | 2015-04-14 | Devicor Medical Products, Inc. | Biopsy device with vacuum assisted bleeding control |
US20080004545A1 (en) * | 2005-08-05 | 2008-01-03 | Garrison William A | Trigger Fired Radial Plate Specimen Retrieval Biopsy Instrument |
US7867173B2 (en) | 2005-08-05 | 2011-01-11 | Devicor Medical Products, Inc. | Biopsy device with replaceable probe and incorporating vibration insertion assist and static vacuum source sample stacking retrieval |
US11224412B2 (en) | 2005-08-05 | 2022-01-18 | Devicor Medical Products, Inc. | Biopsy device with translating valve member |
US7662109B2 (en) | 2006-02-01 | 2010-02-16 | Ethicon Endo-Surgery, Inc. | Biopsy device with replaceable probe incorporating static vacuum source dual valve sample stacking retrieval and saline flush |
EP2319418A2 (de) | 2006-02-01 | 2011-05-11 | Ethicon Endo-Surgery, Inc. | Biopsievorrichtung mit austauschbarer Sonde mit Zweiventilprobenstapelrückgewinnung mit statischer Vakuumquelle und Salzspülung |
US20070179401A1 (en) * | 2006-02-01 | 2007-08-02 | Ethicon Endo-Surgery, Inc. | Biopsy device with replaceable probe incorporating static vacuum source dual valve sample stacking retrieval and saline flush |
US7491177B2 (en) | 2006-02-03 | 2009-02-17 | Ethicon Endo-Surgery, Inc. | Biopsy needle and method |
US20070185411A1 (en) * | 2006-02-03 | 2007-08-09 | Hibner John A | Biopsy needle and method |
US20070191732A1 (en) * | 2006-02-10 | 2007-08-16 | Voegele James W | Cryogenic probe |
US7766843B2 (en) | 2006-03-03 | 2010-08-03 | Ethicon Endo-Surgery, Inc. | Biopsy method |
US20070208271A1 (en) * | 2006-03-03 | 2007-09-06 | Voegele James W | Biopsy method |
US7806834B2 (en) | 2006-03-07 | 2010-10-05 | Devicor Medical Products, Inc. | Device for minimally invasive internal tissue removal |
US7670299B2 (en) | 2006-03-07 | 2010-03-02 | Ethincon Endo-Surgery, Inc. | Device for minimally invasive internal tissue removal |
US20090171218A1 (en) * | 2006-03-24 | 2009-07-02 | Per Ehrenreich Nygaard | Biopsy System |
US9539025B2 (en) * | 2006-03-24 | 2017-01-10 | B-K Medical Aps | Biopsy system |
US20070239064A1 (en) * | 2006-03-29 | 2007-10-11 | Cicenas Chris W | Device for minimally invasive internal tissue removal |
US20070232953A1 (en) * | 2006-03-31 | 2007-10-04 | Ethicon Endo-Surgery, Inc. | MRI biopsy device |
US20100298693A1 (en) * | 2006-03-31 | 2010-11-25 | Devicor Medical Products, Inc. | Breast compression assembly for use in mri biopsy procedure |
US7507210B2 (en) | 2006-05-01 | 2009-03-24 | Ethicon Endo-Surgery, Inc. | Biopsy cannula adjustable depth stop |
US10123820B2 (en) | 2006-05-01 | 2018-11-13 | Devicor Medical Products, Inc. | Grid and rotatable cube guide localization fixture for biopsy device |
US20070255168A1 (en) * | 2006-05-01 | 2007-11-01 | Hibner John A | Grid and rotatable cube guide localization fixture for biopsy device |
EP3263041A1 (de) | 2006-05-01 | 2018-01-03 | Devicor Medical Products, Inc. | Biopsienadel mit einstellbarem tiefenstopp |
US20070255170A1 (en) * | 2006-05-01 | 2007-11-01 | Hibner John A | Biopsy cannula adjustable depth stop |
EP2111799A1 (de) | 2006-05-01 | 2009-10-28 | Ethicon Endo-Surgery, Inc. | Biopsienadel mit einstellbarem Tiefenstopp |
US20090163830A1 (en) * | 2006-05-01 | 2009-06-25 | Hibner John A | Biopsy cannula adjustable depth stop |
US8568333B2 (en) | 2006-05-01 | 2013-10-29 | Devicor Medical Products, Inc. | Grid and rotatable cube guide localization fixture for biopsy device |
US9433401B2 (en) | 2006-05-01 | 2016-09-06 | Devicor Medical Products, Inc. | Biopsy cannula adjustable depth stop |
US10327805B2 (en) | 2006-05-01 | 2019-06-25 | Devicor Medical Products, Inc. | Biopsy cannula adjustable depth stop |
US20080071164A1 (en) * | 2006-07-31 | 2008-03-20 | The Trustees Of Dartmouth College | Devices And Methods For Combined Optical And Magnetic Resonance Imaging |
US8886284B2 (en) * | 2006-07-31 | 2014-11-11 | The Trustees Of Dartmouth College | Devices and methods for combined optical and magnetic resonance imaging |
US10966691B2 (en) | 2006-12-13 | 2021-04-06 | Devicor Medical Products, Inc. | Biopsy sample storage |
US10517577B2 (en) | 2006-12-13 | 2019-12-31 | Devicor Medical Products, Inc. | Presentation of biopsy sample by biopsy device |
EP1932482A1 (de) | 2006-12-13 | 2008-06-18 | Ethicon Endo-Surgery, Inc. | Biopsieprobenlagerung |
US8968212B2 (en) | 2006-12-13 | 2015-03-03 | Devicor Medical Products, Inc. | Biopsy device with motorized needle cocking |
US9345457B2 (en) | 2006-12-13 | 2016-05-24 | Devicor Medical Products, Inc. | Presentation of biopsy sample by biopsy device |
EP1932481A1 (de) | 2006-12-13 | 2008-06-18 | Ethicon Endo-Surgery, Inc. | Biopsiesystem mit Vakuumkontrollmodul |
US9974523B2 (en) | 2006-12-13 | 2018-05-22 | Devicor Medical Products, Inc. | Biopsy sample storage |
US9095326B2 (en) | 2006-12-13 | 2015-08-04 | Devicor Medical Products, Inc. | Biopsy system with vacuum control module |
US9462999B2 (en) | 2006-12-13 | 2016-10-11 | Devicor Medical Products, Inc. | Biopsy sample storage |
US10905403B2 (en) | 2006-12-13 | 2021-02-02 | Devicor Medical Products, Inc. | Presentation of biopsy sample by biopsy device |
US9486184B2 (en) | 2006-12-13 | 2016-11-08 | Devicor Medical Products, Inc. | Biopsy sample storage |
US7981049B2 (en) | 2006-12-13 | 2011-07-19 | Devicor Medical Products, Inc. | Engagement interface for biopsy system vacuum module |
US11179141B2 (en) | 2006-12-13 | 2021-11-23 | Devicor Medical Products, Inc. | Biopsy system |
US8480595B2 (en) | 2006-12-13 | 2013-07-09 | Devicor Medical Products, Inc. | Biopsy device with motorized needle cocking |
US7938786B2 (en) | 2006-12-13 | 2011-05-10 | Devicor Medical Products, Inc. | Vacuum timing algorithm for biopsy device |
US8251916B2 (en) | 2006-12-13 | 2012-08-28 | Devicor Medical Products, Inc. | Revolving tissue sample holder for biopsy device |
US8147423B2 (en) | 2007-03-01 | 2012-04-03 | Dune Medical Devices, Ltd. | Tissue-characterization system and method |
US20080214953A1 (en) * | 2007-03-01 | 2008-09-04 | Dune Medical Devices Ltd. | Tissue-characterization system and method |
US20090012388A1 (en) * | 2007-05-03 | 2009-01-08 | Marvel Medtech, Llc | Interventional device |
EP2022406A2 (de) | 2007-07-25 | 2009-02-11 | Ethicon Endo-Surgery, Inc. | Mit Auslöser betriebenes Biopsie-Instrument zur Probenentnahme mit Radialplatte |
US20090066664A1 (en) * | 2007-09-07 | 2009-03-12 | Hong Fu Jin Precision Industry (Shenzhen) Co., Ltd. | Touch screen and display method thereof |
US8202229B2 (en) | 2007-10-01 | 2012-06-19 | Suros Surgical Systems, Inc. | Surgical device |
US8808200B2 (en) | 2007-10-01 | 2014-08-19 | Suros Surgical Systems, Inc. | Surgical device and method of using same |
US8187204B2 (en) | 2007-10-01 | 2012-05-29 | Suros Surgical Systems, Inc. | Surgical device and method for using same |
US7575556B2 (en) | 2007-11-20 | 2009-08-18 | Ethicon Endo-Surgery, Inc. | Deployment device interface for biopsy device |
US8052616B2 (en) | 2007-11-20 | 2011-11-08 | Devicor Medical Products, Inc. | Biopsy device with fine pitch drive train |
US9039634B2 (en) | 2007-11-20 | 2015-05-26 | Devicor Medical Products, Inc. | Biopsy device tissue sample holder rotation control |
US9433403B2 (en) | 2007-11-20 | 2016-09-06 | Devicor Medical Products, Inc. | Icon-based user interface on biopsy system control module |
US8454531B2 (en) | 2007-11-20 | 2013-06-04 | Devicor Medical Products, Inc. | Icon-based user interface on biopsy system control module |
US7858038B2 (en) | 2007-11-20 | 2010-12-28 | Devicor Medical Products, Inc. | Biopsy device with illuminated tissue holder |
US20090131817A1 (en) * | 2007-11-20 | 2009-05-21 | Speeg Trevor W V | Deployment device interface for biopsy device |
US7806835B2 (en) | 2007-11-20 | 2010-10-05 | Devicor Medical Products, Inc. | Biopsy device with sharps reduction feature |
US8290569B2 (en) | 2007-11-23 | 2012-10-16 | Hologic, Inc. | Open architecture tabletop patient support and coil system |
US20090149738A1 (en) * | 2007-11-23 | 2009-06-11 | Cameron Anthony Piron | Chest Wall Coil Array for Breast Imaging |
US8744550B2 (en) | 2007-11-23 | 2014-06-03 | Hologic, Inc. | Open architecture tabletop patient support and coil system |
US20090216110A1 (en) * | 2007-11-23 | 2009-08-27 | Cameron Piron | Open Architecture Tabletop Patient Support and Coil System |
US8374676B2 (en) * | 2007-11-23 | 2013-02-12 | Hologic, Inc. | Chest wall coil array for breast imaging |
US8864682B2 (en) | 2007-12-27 | 2014-10-21 | Devicor Medical Products, Inc. | Clutch and valving system for tetherless biopsy device |
US20090171242A1 (en) * | 2007-12-27 | 2009-07-02 | Hibner John A | Clutch and valving system for tetherless biopsy device |
US7854706B2 (en) | 2007-12-27 | 2010-12-21 | Devicor Medical Products, Inc. | Clutch and valving system for tetherless biopsy device |
US8454532B2 (en) | 2007-12-27 | 2013-06-04 | Devicor Medical Products, Inc. | Clutch and valving system for tetherless biopsy device |
US20090247901A1 (en) * | 2008-03-25 | 2009-10-01 | Brian Zimmer | Latching side removal spacer |
US20090247900A1 (en) * | 2008-03-25 | 2009-10-01 | Brian Zimmer | Push button adjustable spacer |
EP2786710A3 (de) * | 2008-04-23 | 2014-10-15 | Devicor Medical Products, Inc. | PEM- und BSGI-Biopsievorrichtungen |
US20090275858A1 (en) * | 2008-05-02 | 2009-11-05 | Hardin Terry D | Adjustable spacer |
US8043316B2 (en) | 2008-05-02 | 2011-10-25 | Suros Surgical Systems, Inc. | Adjustable spacer |
US8162852B2 (en) | 2008-10-23 | 2012-04-24 | Devicor Medical Products, Inc. | Methods for medical device alignment |
US20100106056A1 (en) * | 2008-10-23 | 2010-04-29 | Norris Perry R | Methods for medical device alignment |
US20100106015A1 (en) * | 2008-10-23 | 2010-04-29 | Norris Perry R | Medical device alignment |
US20150374273A1 (en) * | 2008-10-29 | 2015-12-31 | Vasculogic, Llc | Automated vessel puncture device using three-dimensional(3d) near infrared (nir) imaging and a robotically driven needle |
US9743875B2 (en) * | 2008-10-29 | 2017-08-29 | Vasculogic, Llc | Automated vessel puncture device using three-dimensional(3D) near infrared (NIR) imaging and a robotically driven needle |
US8366635B2 (en) | 2008-12-18 | 2013-02-05 | Devicor Medical Products, Inc. | Biopsy probe and targeting set interface |
US9561020B2 (en) | 2008-12-18 | 2017-02-07 | Devicor Medical Products, Inc. | Biopsy probe and targeting set interface |
US7862518B2 (en) | 2008-12-18 | 2011-01-04 | Devicor Medical Products, Inc. | Biopsy device with telescoping cutter cover |
US7846109B2 (en) | 2008-12-18 | 2010-12-07 | Devicor Medical Products, Inc. | Biopsy device with sliding cutter cover |
US8167815B2 (en) * | 2008-12-18 | 2012-05-01 | Devicor Medical Products, Inc. | Biopsy device with retractable cutter |
US8460206B2 (en) | 2008-12-18 | 2013-06-11 | Devicor Medical Products, Inc. | Multi-orientation targeting set for MRI biopsy device |
WO2010080302A1 (en) * | 2008-12-18 | 2010-07-15 | Ethicon Endo-Surgery, Inc. | Biopsy device with retractable cutter |
US20100160814A1 (en) * | 2008-12-18 | 2010-06-24 | Parihar Shailendra K | Biopsy Device with Telescoping Cutter Cover |
US8858462B2 (en) | 2008-12-18 | 2014-10-14 | Devicor Medical Products, Inc. | Biopsy probe and targeting set interface |
US20100160825A1 (en) * | 2008-12-18 | 2010-06-24 | Parihar Shailendra K | Targeting Set for MRI Biopsy Device with Probe Holster Support |
US20100160810A1 (en) * | 2008-12-18 | 2010-06-24 | Parihar Shailendra K | Multi-Orientation Targeting Set for MRI Biopsy Device |
CN103622723A (zh) * | 2008-12-18 | 2014-03-12 | 德威科医疗产品公司 | 活检系统 |
US8702623B2 (en) | 2008-12-18 | 2014-04-22 | Devicor Medical Products, Inc. | Biopsy device with discrete tissue chambers |
US9398922B2 (en) * | 2008-12-18 | 2016-07-26 | Devicor Medical Products, Inc. | Targeting set for MRI biopsy device with probe holster support |
US20100160811A1 (en) * | 2008-12-18 | 2010-06-24 | Parihar Shailendra K | Z-Stop Feature of Targeting Set for MRI Biopsy Device |
US20100160823A1 (en) * | 2008-12-18 | 2010-06-24 | Parihar Shailendra K | Biopsy Probe and Targeting Set Interface |
US20100160821A1 (en) * | 2008-12-18 | 2010-06-24 | Parihar Shailendra K | Biopsy Device with Sliding Cutter Cover |
US20100160822A1 (en) * | 2008-12-18 | 2010-06-24 | Parihar Shailendra K | Biopsy Device with Detachable Needle |
US20100160815A1 (en) * | 2008-12-18 | 2010-06-24 | Parihar Shailendra K | Biopsy Device with Retractable Cutter |
US20100317994A1 (en) * | 2009-06-16 | 2010-12-16 | Leimbach Jessica P | Biopsy Targeting Cube with Living Hinges |
US20100317991A1 (en) * | 2009-06-16 | 2010-12-16 | Leimbach Jessica P | Biopsy Targeting Cube with Elastomeric Body |
US20100317990A1 (en) * | 2009-06-16 | 2010-12-16 | Leimbach Jessica P | Biopsy Targeting Cube with Elastomeric Edges |
US20100317993A1 (en) * | 2009-06-16 | 2010-12-16 | Leimbach Jessica P | Biopsy Targeting Cube with Angled Interface |
US8167814B2 (en) | 2009-06-16 | 2012-05-01 | Devicor Medical Products, Inc. | Biopsy targeting cube with malleable members |
EP2266478A2 (de) | 2009-06-16 | 2010-12-29 | Ethicon Endo-Surgery, Inc. | Biopsie-Targeting-Würfel mit Elastomerkörper |
EP2266480A2 (de) | 2009-06-16 | 2010-12-29 | Ethicon Endo-Surgery, Inc. | Biopsie-Targeting-Würfel mit gewinkelter Schnittstelle |
US8197495B2 (en) | 2009-06-16 | 2012-06-12 | Devicor Medical Products, Inc. | Biopsy targeting cube with elastomeric edges |
US20100317992A1 (en) * | 2009-06-16 | 2010-12-16 | Leimbach Jessica P | Biopsy Targeting Cube with Malleable Members |
US8858537B2 (en) | 2009-06-16 | 2014-10-14 | Devicor Medical Products, Inc. | Biopsy targeting cube with living hinges |
EP2266477A2 (de) | 2009-06-16 | 2010-12-29 | Ethicon Endo-Surgery, Inc. | Biopsie-Targeting-Würfel mit formbaren Elementen |
US9463043B2 (en) | 2009-06-16 | 2016-10-11 | Devicor Medical Products, Inc. | Biopsy targeting cube with living hinges |
US8241302B2 (en) | 2009-06-16 | 2012-08-14 | Devicor Medical Products, Inc. | Biopsy targeting cube with angled interface |
EP2266479A2 (de) | 2009-06-16 | 2010-12-29 | Ethicon Endo-Surgery, Inc. | Biopsie-Targeting-Würfel mit lebenden Scharnieren |
US8366634B2 (en) | 2009-06-16 | 2013-02-05 | Devicor Medical Products, Inc. | Biopsy targeting cube with elastomeric body |
EP2263579A2 (de) | 2009-06-16 | 2010-12-22 | Ethicon Endo-Surgery, Inc. | Biopsie-Targeting-Würfel mit Elastomerkanten |
US8206314B2 (en) | 2009-06-17 | 2012-06-26 | Devicor Medical Products, Inc. | MRI biopsy targeting grid with round openings |
US20100324444A1 (en) * | 2009-06-17 | 2010-12-23 | Mollere Rebecca J | MRI Biopsy Targeting Grid Wall Guide |
US20100324445A1 (en) * | 2009-06-17 | 2010-12-23 | Mollere Rebecca J | MRI Biopsy Cylindraceous Targeting Guide |
EP2263578A2 (de) | 2009-06-17 | 2010-12-22 | Ethicon Endo-Surgery, Inc. | MRI-Biopsie-Targeting-Gitter mit runden Öffnungen |
EP2263577A2 (de) | 2009-06-17 | 2010-12-22 | Ethicon Endo-Surgery, Inc. | Zylindrische MRI-Biopsie-Targeting-Führung |
EP2263551A1 (de) | 2009-06-17 | 2010-12-22 | Ethicon Endo-Surgery, Inc. | Wandführung mit MRI-Biopsie-Targeting-Gitter |
US8747331B2 (en) | 2009-06-23 | 2014-06-10 | Hologic, Inc. | Variable angle guide holder for a biopsy guide plug |
US20110082364A1 (en) * | 2009-10-05 | 2011-04-07 | Hibner John A | MRI Biopsy Targeting Cube with Retention Wiper |
WO2011043910A1 (en) | 2009-10-05 | 2011-04-14 | Devicor Medical Products, Inc. | Mri biopsy targeting cube with retention wiper |
US20110092983A1 (en) * | 2009-10-16 | 2011-04-21 | Pawar Ajay D | MRI Biopsy Targeting Cube with Locking Flap |
US20110092847A1 (en) * | 2009-10-16 | 2011-04-21 | Wale Nitin P | MRI Biopsy Targeting Cube with Snap Corners |
US8162849B2 (en) | 2009-10-16 | 2012-04-24 | Devicor Medical Products, Inc. | MRI biopsy targeting cube with gripping arms |
US20110092850A1 (en) * | 2009-10-16 | 2011-04-21 | Kulkarni Abhijit G | MRI Biopsy Targeting Guide with Rotational Lock |
US20110092849A1 (en) * | 2009-10-16 | 2011-04-21 | Deshmukh Santosh G | MRI Biopsy Targeting Cube with Gripping Arms |
US20110092848A1 (en) * | 2009-10-16 | 2011-04-21 | Hibner John A | MRI Biopsy Targeting Cube with Eccentric Lock |
US8162848B2 (en) | 2009-10-16 | 2012-04-24 | Devicor Medical Products, Inc. | MRI biopsy targeting cube with eccentric lock |
US8162847B2 (en) | 2009-10-16 | 2012-04-24 | Devicor Medical Products, Inc. | MRI biopsy targeting cube with snap corners |
US20110201965A1 (en) * | 2010-02-18 | 2011-08-18 | John Anthony Hibner | MRI Compatible Biopsy Device |
US20110224535A1 (en) * | 2010-03-10 | 2011-09-15 | Martina Doehlemann | Magnetic resonance-assisted biopsy examination method, and a magnetic resonance system for implementing the method |
US9220485B2 (en) | 2010-08-28 | 2015-12-29 | Endochoice, Inc. | Tissue collection and separation device |
US9788818B2 (en) | 2010-08-28 | 2017-10-17 | Endochoice, Inc. | Tissue collection and separation device |
US9332926B2 (en) | 2010-11-25 | 2016-05-10 | Invivo Corporation | MRI imaging probe |
US10595831B2 (en) | 2012-05-30 | 2020-03-24 | Devicor Medical Products, Inc. | Control for biopsy device |
WO2014084961A1 (en) | 2012-10-08 | 2014-06-05 | Devicor Medical Products, Inc. | Tissue biopsy device with thumbwheel and sample holder |
US9980705B2 (en) | 2012-10-08 | 2018-05-29 | Devicor Medical Products, Inc. | Tissue biopsy device with selectively rotatably linked thumbwheel and tissue sample holder |
US9474511B2 (en) | 2012-10-08 | 2016-10-25 | Devicor Medical Products, Inc. | Tissue biopsy device with selectively rotatable linked thumbwheel and tissue sample holder |
US20150250449A1 (en) * | 2012-11-23 | 2015-09-10 | Kabushiki Kaisha Toshiba | Puncture adapter and ultrasound probe |
US20150250447A1 (en) * | 2012-11-23 | 2015-09-10 | Kabushiki Kaisha Toshiba | Puncture adapter and ultrasound probe |
US20150313471A1 (en) * | 2013-01-24 | 2015-11-05 | University Court Of The University Of St Andrews | Optical apparatus for use with a medical imager |
US10588513B2 (en) * | 2013-01-24 | 2020-03-17 | University Court Of The University Of St Andrews | Optical apparatus for use with a medical imager |
US9646376B2 (en) | 2013-03-15 | 2017-05-09 | Hologic, Inc. | System and method for reviewing and analyzing cytological specimens |
CN104147689A (zh) * | 2014-03-24 | 2014-11-19 | 天津大学 | 核磁图像导航下乳腺穿刺手术机构 |
US10786224B2 (en) | 2016-04-21 | 2020-09-29 | Covidien Lp | Biopsy devices and methods of use thereof |
US10952654B2 (en) | 2017-03-14 | 2021-03-23 | International Business Machines Corporation | PH sensitive surgical tool |
US11510598B2 (en) | 2017-03-14 | 2022-11-29 | International Business Machines Corporation | PH sensitive surgical tool |
US11331161B2 (en) | 2018-03-23 | 2022-05-17 | Covidien Lp | Surgical assemblies facilitating tissue marking and methods of use thereof |
US11253165B2 (en) | 2019-04-24 | 2022-02-22 | Mohammad Nasser | Intravascular MRI probe assembly |
US11517294B2 (en) | 2019-05-07 | 2022-12-06 | Covidien Lp | Biopsy devices and methods of use thereof |
CN112168302A (zh) * | 2020-10-14 | 2021-01-05 | 商晓杰 | 一种心脏彩超定位穿刺装置 |
Also Published As
Publication number | Publication date |
---|---|
DE60314037T2 (de) | 2008-01-31 |
US20110015542A1 (en) | 2011-01-20 |
DE60314037D1 (de) | 2007-07-12 |
US8808198B2 (en) | 2014-08-19 |
EP1356772A3 (de) | 2004-02-18 |
EP1356772B1 (de) | 2007-05-30 |
EP1356772A2 (de) | 2003-10-29 |
US20140336529A1 (en) | 2014-11-13 |
JP2004033752A (ja) | 2004-02-05 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
US8808198B2 (en) | MRI compatible biopsy device with detachable probe | |
EP1356774B1 (de) | Verfahren zur Benutzung einer NMR-kompatiblen Biopsievorrichtung mit abnehmbarer Sonde vor der Biopsie | |
US7826883B2 (en) | Localization mechanism for an MRI compatible biopsy device | |
US7438692B2 (en) | Localization mechanism for an MRI compatible biopsy device | |
US6626849B2 (en) | MRI compatible surgical biopsy device | |
US8123697B2 (en) | Method and apparatus for MR-guided biopsy | |
US7192404B2 (en) | MRI compatible surgical biopsy device having a tip which leaves an artifact | |
US6942627B2 (en) | Surgical biopsy device having a flexible cutter | |
EP1520518B1 (de) | Biopsiegerät mit internem Probenentnahmemechanismus | |
US20110201965A1 (en) | MRI Compatible Biopsy Device | |
US20040092810A1 (en) | Method and apparatus for MR-guided biopsy | |
EP1820453B1 (de) | NMR-kompatible Biopsievorrichtung mit abnehmbarer Sonde | |
EP3355826A1 (de) | Kompressionskissen für brustunterstützung | |
WO2002062227A1 (en) | Biopsy apparatus and method |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
AS | Assignment |
Owner name: ETHICON ENDO-SURGERY, OHIO Free format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNORS:HIBNER, JOHN ANTHONY;ALBRECHT, THOMAS EDWARD;SCHWEMBERGER, RICHARD F.;AND OTHERS;REEL/FRAME:013002/0064 Effective date: 20020605 |
|
AS | Assignment |
Owner name: DEVICOR MEDICAL PRODUCTS, INC., WISCONSIN Free format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNOR:ETHICON ENDO-SURGERY, INC.;REEL/FRAME:024656/0606 Effective date: 20100709 |
|
AS | Assignment |
Owner name: GENERAL ELECTRIC CAPITAL CORPORATION, AS AGENT, MA Free format text: SECURITY AGREEMENT;ASSIGNOR:DEVICOR MEDICAL PRODUCTS, INC.;REEL/FRAME:024672/0088 Effective date: 20100709 |
|
STCB | Information on status: application discontinuation |
Free format text: ABANDONED -- FAILURE TO RESPOND TO AN OFFICE ACTION |