US20030185882A1 - Pharmaceutical compositions containing oxybutynin - Google Patents
Pharmaceutical compositions containing oxybutynin Download PDFInfo
- Publication number
- US20030185882A1 US20030185882A1 US09/992,488 US99248801A US2003185882A1 US 20030185882 A1 US20030185882 A1 US 20030185882A1 US 99248801 A US99248801 A US 99248801A US 2003185882 A1 US2003185882 A1 US 2003185882A1
- Authority
- US
- United States
- Prior art keywords
- drug
- oxybutynin
- osmotic device
- dosage form
- order
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/216—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acids having aromatic rings, e.g. benactizyne, clofibrate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
- A61K9/0004—Osmotic delivery systems; Sustained release driven by osmosis, thermal energy or gas
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
- A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
Priority Applications (14)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/992,488 US20030185882A1 (en) | 2001-11-06 | 2001-11-06 | Pharmaceutical compositions containing oxybutynin |
EP02798241A EP1461018A2 (en) | 2001-11-06 | 2002-11-06 | Dual controlled release dosage form |
UY27533A UY27533A1 (es) | 2001-11-06 | 2002-11-06 | Composiciones farmacéuticas que contienen oxibutinina |
AU2002363361A AU2002363361A1 (en) | 2001-11-06 | 2002-11-06 | Pharmaceutical compositions containing oxybutynin |
BR0213948-0A BR0213948A (pt) | 2001-11-06 | 2002-11-06 | Forma de dosagem de liberação controlada dual |
PCT/CR2002/000006 WO2003039519A2 (es) | 2001-11-06 | 2002-11-06 | Forma de dosificación de liberación controlada dual |
UY27532A UY27532A1 (es) | 2001-11-06 | 2002-11-06 | Forma de dosificación de liberación controlada dual. |
AU2002363360A AU2002363360A1 (en) | 2001-11-06 | 2002-11-06 | Dual controlled release dosage form |
ARP020104230A AR037255A1 (es) | 2001-11-06 | 2002-11-06 | Composiciones farmaceuticas que contienen oxibutinina |
ARP020104231A AR037256A1 (es) | 2001-11-06 | 2002-11-06 | Forma de dosificacion de liberacion controlada dual |
PCT/CR2002/000007 WO2003039436A2 (es) | 2001-11-06 | 2002-11-06 | Composiciones farmaceuticas que contienen oxibutinina |
US11/321,736 US8241667B2 (en) | 2001-11-06 | 2005-12-29 | Dual controlled release osmotic device |
US11/355,315 US8329217B2 (en) | 2001-11-06 | 2006-02-15 | Dual controlled release dosage form |
US13/625,658 US8591947B2 (en) | 2001-11-06 | 2012-09-24 | Dual controlled release dosage form |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/992,488 US20030185882A1 (en) | 2001-11-06 | 2001-11-06 | Pharmaceutical compositions containing oxybutynin |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US11/321,736 Division US8241667B2 (en) | 2001-11-06 | 2005-12-29 | Dual controlled release osmotic device |
Publications (1)
Publication Number | Publication Date |
---|---|
US20030185882A1 true US20030185882A1 (en) | 2003-10-02 |
Family
ID=25538393
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US09/992,488 Abandoned US20030185882A1 (en) | 2001-11-06 | 2001-11-06 | Pharmaceutical compositions containing oxybutynin |
US11/321,736 Active 2026-05-16 US8241667B2 (en) | 2001-11-06 | 2005-12-29 | Dual controlled release osmotic device |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US11/321,736 Active 2026-05-16 US8241667B2 (en) | 2001-11-06 | 2005-12-29 | Dual controlled release osmotic device |
Country Status (7)
Country | Link |
---|---|
US (2) | US20030185882A1 (es) |
EP (1) | EP1461018A2 (es) |
AR (2) | AR037256A1 (es) |
AU (2) | AU2002363361A1 (es) |
BR (1) | BR0213948A (es) |
UY (2) | UY27533A1 (es) |
WO (2) | WO2003039519A2 (es) |
Cited By (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20010009995A1 (en) * | 1998-03-26 | 2001-07-26 | Gupta Suneel K. | Oxybutynin therapy |
US20030175346A1 (en) * | 2002-02-01 | 2003-09-18 | Anne Billotte | Osmotic delivery system |
US20040091529A1 (en) * | 2002-06-26 | 2004-05-13 | David Edgren | Methods and dosage forms for increasing solubility of drug compositions for controlled delivery |
US20040115262A1 (en) * | 2002-07-29 | 2004-06-17 | Frank Jao | Formulations and dosage forms for controlled delivery of topiramate |
US20050058707A1 (en) * | 2003-08-06 | 2005-03-17 | Iran Reyes | Uniform delivery of topiramate over prolonged period of time with enhanced dispersion formulation |
US20050175696A1 (en) * | 2003-12-29 | 2005-08-11 | David Edgren | Drug granule coatings that impart smear resistance during mechanical compression |
US20050175690A1 (en) * | 2003-12-29 | 2005-08-11 | David Edgren | Novel drug compositions and dosage forms |
US20050175697A1 (en) * | 2003-12-29 | 2005-08-11 | David Edgren | Novel drug compositions and dosage forms of topiramate |
US20050191351A1 (en) * | 2003-11-04 | 2005-09-01 | Shire Laboratories, Inc. | Once daily dosage forms of trospium |
WO2005105036A1 (en) * | 2004-04-28 | 2005-11-10 | Natco Pharma Limited | Controlled release mucoadhesive matrix formulation containing tolterodine and a process for its preparation |
US20050271691A1 (en) * | 2003-02-21 | 2005-12-08 | Cardio Combos Llc | Prepackaged aqueous pharmaceutical formulations |
EP1629834A1 (en) * | 2004-08-27 | 2006-03-01 | KRKA, D.D., Novo Mesto | Sustained release pharmaceutical composition of tolterodine |
US20060141050A1 (en) * | 2002-03-26 | 2006-06-29 | Lerner Itzhak E | Drug microparticles |
US20090022797A1 (en) * | 2007-07-20 | 2009-01-22 | Mylan Pharmaceuticals Inc | Stabilized tolterodine tartrate formulations |
WO2009014533A1 (en) * | 2007-07-20 | 2009-01-29 | Mylan Pharmaceuticals , Inc | Drug formulations having inert sealed cores |
WO2009052353A2 (en) * | 2007-10-17 | 2009-04-23 | Dr. Reddy's Laboratories Ltd. | Trospium pharmaceutical formulations |
CN102048706A (zh) * | 2011-01-12 | 2011-05-11 | 山东创新药物研发有限公司 | 一种氢溴酸达非那新缓释片及制备方法 |
CN103127023A (zh) * | 2013-03-01 | 2013-06-05 | 南京正宽医药科技有限公司 | 一种盐酸度洛西汀肠溶片及其制备方法 |
US8709476B2 (en) | 2003-11-04 | 2014-04-29 | Supernus Pharmaceuticals, Inc. | Compositions of quaternary ammonium compounds containing bioavailability enhancers |
US8871275B2 (en) | 2007-08-08 | 2014-10-28 | Inventia Healthcare Private Limited | Extended release compositions comprising tolterodine |
US8932628B2 (en) | 2005-06-27 | 2015-01-13 | Valeant International Bermuda | Modified release formulations of a bupropion salt |
US9393192B2 (en) | 2002-07-29 | 2016-07-19 | Alza Corporation | Methods and dosage forms for controlled delivery of paliperidone and risperidone |
US20200206130A1 (en) * | 2017-05-23 | 2020-07-02 | Catalent UK Supply Chain Limited | Implantable drug delivery device |
US20210145753A1 (en) * | 2012-05-14 | 2021-05-20 | Shionogi & Co., Ltd. | Preparation containing 6,7-unsaturated-7-carbamoyl morphinan derivatives |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8329217B2 (en) | 2001-11-06 | 2012-12-11 | Osmotica Kereskedelmi Es Szolgaltato Kft | Dual controlled release dosage form |
US7785627B2 (en) * | 2002-09-20 | 2010-08-31 | Watson Pharmaceuticals, Inc. | Pharmaceutical formulation containing a biguanide and a thiazolidinedione derivative |
US9060941B2 (en) | 2002-09-20 | 2015-06-23 | Actavis, Inc. | Pharmaceutical formulation containing a biguanide and a thiazolidinedione derivative |
US7959946B2 (en) | 2002-09-20 | 2011-06-14 | Watson Pharmaceuticals, Inc. | Pharmaceutical formulation containing a biguanide and a thiazolidinedione derivative |
JP2007522249A (ja) * | 2004-02-13 | 2007-08-09 | ニューロモレキュラー・インコーポレイテッド | 精神医学的状態の処置のための、nmdaレセプターアンタゴニストと、抗うつ薬であるmaoインヒビターまたはgadphインヒビターとの併用 |
AR053986A1 (es) | 2004-12-03 | 2007-05-30 | Osmotica Pharmaceutical Argent | Dispositivo osmotico que contiene amantadina y una sal osmotica |
BRPI0518506A2 (pt) | 2005-01-27 | 2008-12-02 | Alembic Ltd | tablete e formulaÇço de liberaÇço prolongada de levetiracetam |
EP2032124A1 (en) * | 2006-06-27 | 2009-03-11 | Biovail Laboratories International Srl | Multiparticulate osmotic delivery system |
US20080014264A1 (en) * | 2006-07-13 | 2008-01-17 | Ucb, S.A. | Novel pharmaceutical compositions comprising levetiracetam |
WO2010089259A2 (en) | 2009-02-04 | 2010-08-12 | Woerwag R&D Gmbh | Sustained release composition containing quetiapine |
WO2011161504A1 (en) * | 2010-06-23 | 2011-12-29 | Micro Labs Limited | Extended release formulations containing darifenacin or pharmaceutically acceptable salts thereof |
CN103156804A (zh) * | 2011-12-13 | 2013-06-19 | 重庆医药工业研究院有限责任公司 | 一种奥昔布宁透皮凝胶及其制备方法 |
BR112020015316A2 (pt) * | 2018-01-30 | 2020-12-08 | Apnimed, Inc. (Delaware) | Métodos e composições para o tratamento da apneia do sono |
Citations (37)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4111202A (en) * | 1976-11-22 | 1978-09-05 | Alza Corporation | Osmotic system for the controlled and delivery of agent over time |
US4309996A (en) * | 1980-04-28 | 1982-01-12 | Alza Corporation | System with microporous releasing diffusor |
US4327725A (en) * | 1980-11-25 | 1982-05-04 | Alza Corporation | Osmotic device with hydrogel driving member |
US4449983A (en) * | 1982-03-22 | 1984-05-22 | Alza Corporation | Simultaneous delivery of two drugs from unit delivery device |
US4455143A (en) * | 1982-03-22 | 1984-06-19 | Alza Corporation | Osmotic device for dispensing two different medications |
US4612008A (en) * | 1983-05-11 | 1986-09-16 | Alza Corporation | Osmotic device with dual thermodynamic activity |
US4624847A (en) * | 1985-04-22 | 1986-11-25 | Alza Corporation | Drug delivery device for programmed delivery of beneficial drug |
US4627971A (en) * | 1985-04-22 | 1986-12-09 | Alza Corporation | Osmotic device with self-sealing passageway |
US4662880A (en) * | 1986-03-14 | 1987-05-05 | Alza Corporation | Pseudoephedrine, brompheniramine therapy |
US4681583A (en) * | 1982-12-20 | 1987-07-21 | Alza Corporation | System for dispersing drug in biological environment |
US4723957A (en) * | 1986-02-07 | 1988-02-09 | Alza Corp. | System for delivering drug with enhanced bioacceptability |
US4765989A (en) * | 1983-05-11 | 1988-08-23 | Alza Corporation | Osmotic device for administering certain drugs |
US4765957A (en) * | 1986-12-29 | 1988-08-23 | Carondelet Foundry Company | Alloy resistant to seawater and other corrosive fluids |
US4814181A (en) * | 1987-09-03 | 1989-03-21 | Alza Corporation | Dosage form comprising fast agent delivery followed by slow agent delivery |
US4863456A (en) * | 1986-04-30 | 1989-09-05 | Alza Corporation | Dosage form with improved delivery capability |
US4867969A (en) * | 1986-02-07 | 1989-09-19 | Alza Corporation | Hydrogel formulation for administering non-steroidal drugs |
US4909474A (en) * | 1987-05-15 | 1990-03-20 | Dyckerhoff & Widmann Aktiengessellschaft | Apparatus for locating operational surfaces on a track for electromagnetically levitated vehicles |
US4915954A (en) * | 1987-09-03 | 1990-04-10 | Alza Corporation | Dosage form for delivering a drug at two different rates |
US4931285A (en) * | 1988-04-28 | 1990-06-05 | Alza Corporation | Aqueous based pharmaceutical coating composition for dosage forms |
US4960416A (en) * | 1986-04-30 | 1990-10-02 | Alza Corporation | Dosage form with improved delivery capability |
US4971790A (en) * | 1986-02-07 | 1990-11-20 | Alza Corporation | Dosage form for lessening irritation of mocusa |
US5006348A (en) * | 1990-05-04 | 1991-04-09 | Kraft General Foods, Inc. | Method for manufacture of swiss cheese |
US5082668A (en) * | 1983-05-11 | 1992-01-21 | Alza Corporation | Controlled-release system with constant pushing source |
US5160743A (en) * | 1988-04-28 | 1992-11-03 | Alza Corporation | Annealed composition for pharmaceutically acceptable drug |
US5160744A (en) * | 1991-06-27 | 1992-11-03 | Alza Corporation | Verapmil therapy |
US5190785A (en) * | 1990-06-13 | 1993-03-02 | Manfred Oelsner | Method for the manufacture of pectinous and sacchariferous preparations, such as jam, marmalade or the like |
US5208037A (en) * | 1991-04-22 | 1993-05-04 | Alza Corporation | Dosage forms comprising polymers comprising different molecular weights |
US5252338A (en) * | 1991-06-27 | 1993-10-12 | Alza Corporation | Therapy delayed |
US5399359A (en) * | 1994-03-04 | 1995-03-21 | Edward Mendell Co., Inc. | Controlled release oxybutynin formulations |
US5543155A (en) * | 1993-12-09 | 1996-08-06 | Egis Gyogyszergyar Rt. | Diffusion-osmotic controlled drug-release pharmaceutical composition and process for preparing same |
US5674895A (en) * | 1995-05-22 | 1997-10-07 | Alza Corporation | Dosage form comprising oxybutynin |
US5788987A (en) * | 1997-01-29 | 1998-08-04 | Poli Industria Chimica Spa | Methods for treating early morning pathologies |
US5866164A (en) * | 1996-03-12 | 1999-02-02 | Alza Corporation | Composition and dosage form comprising opioid antagonist |
US5912268A (en) * | 1995-05-22 | 1999-06-15 | Alza Corporation | Dosage form and method for treating incontinence |
US6106864A (en) * | 1995-09-15 | 2000-08-22 | Pfizer Inc. | Pharmaceutical formulations containing darifenacin |
US20020010216A1 (en) * | 2000-02-24 | 2002-01-24 | Karen Rogosky | New drug combinations |
US6562368B2 (en) * | 1999-12-16 | 2003-05-13 | Dermatrends, Inc. | Transdermal administration of oxybutynin using hydroxide-releasing agents as permeation enhancers |
Family Cites Families (22)
Publication number | Priority date | Publication date | Assignee | Title |
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US4552880A (en) * | 1983-02-15 | 1985-11-12 | Merrell Dow Pharmaceuticals Inc. | Aroylimidazolones |
US4661583A (en) * | 1985-06-24 | 1987-04-28 | Ashland Oil, Inc. | Reaction of bicyclic amide acetal with imide |
WO1988001170A1 (en) * | 1986-08-20 | 1988-02-25 | Teikoku Seiyaku Co., Ltd. | Steroidal drug-containing preparation for external use |
US5236689A (en) * | 1987-06-25 | 1993-08-17 | Alza Corporation | Multi-unit delivery system |
US4996061A (en) * | 1987-10-07 | 1991-02-26 | Merrell Dow Pharmaceuticals Inc. | Pharmaceutical composition for piperidinoalkanol-decongestant combination |
US4904474A (en) | 1988-01-25 | 1990-02-27 | Alza Corporation | Delivery of drug to colon by oral disage form |
US5006346A (en) * | 1988-04-28 | 1991-04-09 | Alza Corporation | Delivery system |
US5976571A (en) * | 1991-01-31 | 1999-11-02 | Port Systems, L.L.C. | Method for making a multi-stage drug delivery system |
US5190765A (en) * | 1991-06-27 | 1993-03-02 | Alza Corporation | Therapy delayed |
JP2646170B2 (ja) | 1992-06-24 | 1997-08-25 | 日本ヘキスト・マリオン・ルセル株式会社 | 徐放性塩酸オキシブチニン製剤 |
US5643155A (en) * | 1993-11-02 | 1997-07-01 | Kallassy; Charles | Aquatic exercise device |
WO1996012477A1 (en) | 1994-10-21 | 1996-05-02 | Leiras Oy | Controlled release oral delivery system containing oxybutynin |
US5677346A (en) * | 1995-01-31 | 1997-10-14 | Sepracor, Inc. | Treating urinary incontinence using (S)-desethyloxybutynin |
WO1997016814A1 (en) | 1995-11-03 | 1997-05-09 | Sierra Semiconductor Corporation | Yuv video backend filter |
JP2665658B2 (ja) | 1995-12-18 | 1997-10-22 | 住友特殊金属株式会社 | 希土類・鉄・コバルト・ボロン系正方晶化合物 |
ES2141044B1 (es) * | 1997-02-26 | 2001-02-01 | Alza Corp | Terapia con oxibutinina. |
US5866184A (en) * | 1997-03-12 | 1999-02-02 | World Class Packaging Systems, Inc. | Method of packaging a food product in a ventable package |
DE69818607T2 (de) * | 1997-05-30 | 2004-07-29 | Osmotica Corp. | Mehrlagige osmosevorrichtung |
SI1039882T1 (sl) | 1998-08-27 | 2011-01-31 | Pfizer Health Ab | Terapevtska formulacija za dajanje tolterodina s kontroliranim sproščanjem |
WO2000019997A1 (en) | 1998-10-07 | 2000-04-13 | Alza Corporation | Controlled release dosage from comprising oxybutynin |
IL141235A (en) * | 2000-02-09 | 2012-04-30 | Novartis Int Pharm Ltd | Combined use of an alpha-adrenoceptor antagonist and a muscarinic antagonist in the preparation of a drug for the treatment of non-malignant prostatic hyperplasia |
US8329217B2 (en) * | 2001-11-06 | 2012-12-11 | Osmotica Kereskedelmi Es Szolgaltato Kft | Dual controlled release dosage form |
-
2001
- 2001-11-06 US US09/992,488 patent/US20030185882A1/en not_active Abandoned
-
2002
- 2002-11-06 EP EP02798241A patent/EP1461018A2/en not_active Withdrawn
- 2002-11-06 AR ARP020104231A patent/AR037256A1/es not_active Application Discontinuation
- 2002-11-06 AR ARP020104230A patent/AR037255A1/es not_active Application Discontinuation
- 2002-11-06 UY UY27533A patent/UY27533A1/es not_active Application Discontinuation
- 2002-11-06 BR BR0213948-0A patent/BR0213948A/pt not_active Application Discontinuation
- 2002-11-06 UY UY27532A patent/UY27532A1/es not_active Application Discontinuation
- 2002-11-06 AU AU2002363361A patent/AU2002363361A1/en not_active Abandoned
- 2002-11-06 AU AU2002363360A patent/AU2002363360A1/en not_active Abandoned
- 2002-11-06 WO PCT/CR2002/000006 patent/WO2003039519A2/es not_active Application Discontinuation
- 2002-11-06 WO PCT/CR2002/000007 patent/WO2003039436A2/es not_active Application Discontinuation
-
2005
- 2005-12-29 US US11/321,736 patent/US8241667B2/en active Active
Patent Citations (38)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4111202A (en) * | 1976-11-22 | 1978-09-05 | Alza Corporation | Osmotic system for the controlled and delivery of agent over time |
US4309996A (en) * | 1980-04-28 | 1982-01-12 | Alza Corporation | System with microporous releasing diffusor |
US4327725A (en) * | 1980-11-25 | 1982-05-04 | Alza Corporation | Osmotic device with hydrogel driving member |
US4449983A (en) * | 1982-03-22 | 1984-05-22 | Alza Corporation | Simultaneous delivery of two drugs from unit delivery device |
US4455143A (en) * | 1982-03-22 | 1984-06-19 | Alza Corporation | Osmotic device for dispensing two different medications |
US4681583A (en) * | 1982-12-20 | 1987-07-21 | Alza Corporation | System for dispersing drug in biological environment |
US4765989A (en) * | 1983-05-11 | 1988-08-23 | Alza Corporation | Osmotic device for administering certain drugs |
US4612008A (en) * | 1983-05-11 | 1986-09-16 | Alza Corporation | Osmotic device with dual thermodynamic activity |
US5082668A (en) * | 1983-05-11 | 1992-01-21 | Alza Corporation | Controlled-release system with constant pushing source |
US4624847A (en) * | 1985-04-22 | 1986-11-25 | Alza Corporation | Drug delivery device for programmed delivery of beneficial drug |
US4627971A (en) * | 1985-04-22 | 1986-12-09 | Alza Corporation | Osmotic device with self-sealing passageway |
US4723957A (en) * | 1986-02-07 | 1988-02-09 | Alza Corp. | System for delivering drug with enhanced bioacceptability |
US4867969A (en) * | 1986-02-07 | 1989-09-19 | Alza Corporation | Hydrogel formulation for administering non-steroidal drugs |
US4971790A (en) * | 1986-02-07 | 1990-11-20 | Alza Corporation | Dosage form for lessening irritation of mocusa |
US4662880A (en) * | 1986-03-14 | 1987-05-05 | Alza Corporation | Pseudoephedrine, brompheniramine therapy |
US4863456A (en) * | 1986-04-30 | 1989-09-05 | Alza Corporation | Dosage form with improved delivery capability |
US4960416A (en) * | 1986-04-30 | 1990-10-02 | Alza Corporation | Dosage form with improved delivery capability |
US4765957A (en) * | 1986-12-29 | 1988-08-23 | Carondelet Foundry Company | Alloy resistant to seawater and other corrosive fluids |
US4909474A (en) * | 1987-05-15 | 1990-03-20 | Dyckerhoff & Widmann Aktiengessellschaft | Apparatus for locating operational surfaces on a track for electromagnetically levitated vehicles |
US4814181A (en) * | 1987-09-03 | 1989-03-21 | Alza Corporation | Dosage form comprising fast agent delivery followed by slow agent delivery |
US4915954A (en) * | 1987-09-03 | 1990-04-10 | Alza Corporation | Dosage form for delivering a drug at two different rates |
US4931285A (en) * | 1988-04-28 | 1990-06-05 | Alza Corporation | Aqueous based pharmaceutical coating composition for dosage forms |
US5160743A (en) * | 1988-04-28 | 1992-11-03 | Alza Corporation | Annealed composition for pharmaceutically acceptable drug |
US5006348A (en) * | 1990-05-04 | 1991-04-09 | Kraft General Foods, Inc. | Method for manufacture of swiss cheese |
US5190785A (en) * | 1990-06-13 | 1993-03-02 | Manfred Oelsner | Method for the manufacture of pectinous and sacchariferous preparations, such as jam, marmalade or the like |
US5208037A (en) * | 1991-04-22 | 1993-05-04 | Alza Corporation | Dosage forms comprising polymers comprising different molecular weights |
US5160744A (en) * | 1991-06-27 | 1992-11-03 | Alza Corporation | Verapmil therapy |
US5252338A (en) * | 1991-06-27 | 1993-10-12 | Alza Corporation | Therapy delayed |
US5543155A (en) * | 1993-12-09 | 1996-08-06 | Egis Gyogyszergyar Rt. | Diffusion-osmotic controlled drug-release pharmaceutical composition and process for preparing same |
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Also Published As
Publication number | Publication date |
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UY27532A1 (es) | 2003-05-30 |
AR037255A1 (es) | 2004-11-03 |
US20060177510A1 (en) | 2006-08-10 |
WO2003039436A2 (es) | 2003-05-15 |
AU2002363361A1 (en) | 2003-05-19 |
UY27533A1 (es) | 2003-05-30 |
EP1461018A2 (en) | 2004-09-29 |
WO2003039436A3 (es) | 2004-02-26 |
WO2003039519A2 (es) | 2003-05-15 |
BR0213948A (pt) | 2004-08-31 |
AR037256A1 (es) | 2004-11-03 |
US8241667B2 (en) | 2012-08-14 |
AU2002363360A1 (en) | 2003-05-19 |
WO2003039519A3 (es) | 2004-03-25 |
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