US20020035128A1 - Methods for treating parkinson's disease - Google Patents

Methods for treating parkinson's disease Download PDF

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Publication number
US20020035128A1
US20020035128A1 US09/899,028 US89902801A US2002035128A1 US 20020035128 A1 US20020035128 A1 US 20020035128A1 US 89902801 A US89902801 A US 89902801A US 2002035128 A1 US2002035128 A1 US 2002035128A1
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United States
Prior art keywords
group
formula
compound
disease
pharmaceutically acceptable
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
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US09/899,028
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English (en)
Inventor
Raymond Pratt
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Eisai Co Ltd
Original Assignee
Eisai Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eisai Co Ltd filed Critical Eisai Co Ltd
Priority to US09/899,028 priority Critical patent/US20020035128A1/en
Assigned to EISAL CO., LTD. reassignment EISAL CO., LTD. ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: PRATT, RAYMOND D.
Publication of US20020035128A1 publication Critical patent/US20020035128A1/en
Priority to US10/321,653 priority patent/US20030153598A1/en
Priority to US10/806,409 priority patent/US20040180931A1/en
Abandoned legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
US09/899,028 2000-03-03 2001-07-06 Methods for treating parkinson's disease Abandoned US20020035128A1 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
US09/899,028 US20020035128A1 (en) 2000-03-03 2001-07-06 Methods for treating parkinson's disease
US10/321,653 US20030153598A1 (en) 2000-07-25 2002-12-18 Methods for treating Parkinson's disease with cholinesterase inhibitors
US10/806,409 US20040180931A1 (en) 2000-03-03 2004-03-23 Methods for treating Parkinson's disease

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US18674400P 2000-03-03 2000-03-03
US19761000P 2000-04-18 2000-04-18
US22078300P 2000-07-25 2000-07-25
US25922601P 2001-01-03 2001-01-03
PCT/US2001/007027 WO2001066114A1 (en) 2000-03-03 2001-03-05 Novel methods using cholinesterase inhibitors
USPCT/US01/07027 2001-03-05
US09/899,028 US20020035128A1 (en) 2000-03-03 2001-07-06 Methods for treating parkinson's disease

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/007027 Continuation WO2001066114A1 (en) 2000-03-03 2001-03-05 Novel methods using cholinesterase inhibitors

Related Child Applications (1)

Application Number Title Priority Date Filing Date
US10/321,653 Continuation US20030153598A1 (en) 2000-03-03 2002-12-18 Methods for treating Parkinson's disease with cholinesterase inhibitors

Publications (1)

Publication Number Publication Date
US20020035128A1 true US20020035128A1 (en) 2002-03-21

Family

ID=27497683

Family Applications (7)

Application Number Title Priority Date Filing Date
US09/899,028 Abandoned US20020035128A1 (en) 2000-03-03 2001-07-06 Methods for treating parkinson's disease
US09/947,087 Expired - Fee Related US6482838B2 (en) 2000-03-03 2001-09-04 Methods for treating cognitive impairments caused by traumatic brain injuries
US09/947,086 Expired - Lifetime US6458807B1 (en) 2000-03-03 2001-09-04 Methods for treating vascular dementia
US10/054,931 Expired - Fee Related US6576646B1 (en) 2000-03-03 2002-01-25 Methods for treating cognitive impairments caused by traumatic brain injuries
US10/232,406 Expired - Fee Related US6689795B2 (en) 2000-03-03 2002-09-03 Methods for treating dementia due to HIV disease
US10/732,349 Expired - Fee Related US7563808B2 (en) 2000-03-03 2003-12-11 Methods for treating cognitive impairments or dementia
US11/181,855 Abandoned US20050250812A1 (en) 2000-03-03 2005-07-15 Methods for treating lewy body dementia

Family Applications After (6)

Application Number Title Priority Date Filing Date
US09/947,087 Expired - Fee Related US6482838B2 (en) 2000-03-03 2001-09-04 Methods for treating cognitive impairments caused by traumatic brain injuries
US09/947,086 Expired - Lifetime US6458807B1 (en) 2000-03-03 2001-09-04 Methods for treating vascular dementia
US10/054,931 Expired - Fee Related US6576646B1 (en) 2000-03-03 2002-01-25 Methods for treating cognitive impairments caused by traumatic brain injuries
US10/232,406 Expired - Fee Related US6689795B2 (en) 2000-03-03 2002-09-03 Methods for treating dementia due to HIV disease
US10/732,349 Expired - Fee Related US7563808B2 (en) 2000-03-03 2003-12-11 Methods for treating cognitive impairments or dementia
US11/181,855 Abandoned US20050250812A1 (en) 2000-03-03 2005-07-15 Methods for treating lewy body dementia

Country Status (11)

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US (7) US20020035128A1 (US06576646-20030610-C00010.png)
EP (5) EP2140868A1 (US06576646-20030610-C00010.png)
JP (1) JP2003525903A (US06576646-20030610-C00010.png)
AT (1) ATE345803T1 (US06576646-20030610-C00010.png)
AU (1) AU2001249091A1 (US06576646-20030610-C00010.png)
CY (1) CY1107997T1 (US06576646-20030610-C00010.png)
DE (1) DE60124730T2 (US06576646-20030610-C00010.png)
DK (1) DK1311272T3 (US06576646-20030610-C00010.png)
ES (1) ES2275670T3 (US06576646-20030610-C00010.png)
PT (1) PT1311272E (US06576646-20030610-C00010.png)
WO (1) WO2001066114A1 (US06576646-20030610-C00010.png)

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US20050277629A1 (en) * 2004-03-18 2005-12-15 The Brigham And Women's Hospital, Inc. Methods for the treatment of synucleinopathies (Lansbury)
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US20070053976A1 (en) * 2002-05-17 2007-03-08 Eisai R & D Management Co., Ltd. Novel combination of drugs as antidepressant
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US20080131491A1 (en) * 2006-12-01 2008-06-05 Akinori Hanatani Percutaneously absorbable preparation
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AU2001249091A1 (en) 2001-09-17
EP1311272A4 (en) 2003-05-21
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US20040122051A1 (en) 2004-06-24
US6576646B1 (en) 2003-06-10
ATE345803T1 (de) 2006-12-15
US20050250812A1 (en) 2005-11-10
EP1311272A1 (en) 2003-05-21
EP2138177A1 (en) 2009-12-30
DE60124730D1 (de) 2007-01-04
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EP2133078A1 (en) 2009-12-16
US7563808B2 (en) 2009-07-21
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US20020040038A1 (en) 2002-04-04
JP2003525903A (ja) 2003-09-02
US6689795B2 (en) 2004-02-10
US6482838B2 (en) 2002-11-19
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EP2130538A1 (en) 2009-12-09
US20030040532A1 (en) 2003-02-27

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