UA95780C2 - Xanthine derivatives as selective hm74a agonists - Google Patents

Xanthine derivatives as selective hm74a agonists

Info

Publication number
UA95780C2
UA95780C2 UAA200801702A UAA200801702A UA95780C2 UA 95780 C2 UA95780 C2 UA 95780C2 UA A200801702 A UAA200801702 A UA A200801702A UA A200801702 A UAA200801702 A UA A200801702A UA 95780 C2 UA95780 C2 UA 95780C2
Authority
UA
Ukraine
Prior art keywords
xanthine derivatives
compounds
hm74a agonists
selective
derivatives
Prior art date
Application number
UAA200801702A
Other languages
English (en)
Ukrainian (uk)
Inventor
Ричард Джонатан Дениэл Хетли
Эндрю МкМертри Мейсон
Иван Лео Пинто
Original Assignee
Глаксосмитклайн Ллс
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Глаксосмитклайн Ллс filed Critical Глаксосмитклайн Ллс
Publication of UA95780C2 publication Critical patent/UA95780C2/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
    • C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Данное изобретение касается соединений формулы (I), которые являются производными ксантина, способов получения указанных производных, фармацевтических композиций, которые содержат эти соединения, и применения соединений в терапии, например, в лечении заболеваний, при которых предактивация рецептора НМ74А могла бы иметь эффект в отношении заболевания или при которых активация рецептора будет эффективной.(I)
UAA200801702A 2005-08-10 2006-08-08 Xanthine derivatives as selective hm74a agonists UA95780C2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB0516464A GB0516464D0 (en) 2005-08-10 2005-08-10 Novel compounds

Publications (1)

Publication Number Publication Date
UA95780C2 true UA95780C2 (en) 2011-09-12

Family

ID=34984414

Family Applications (1)

Application Number Title Priority Date Filing Date
UAA200801702A UA95780C2 (en) 2005-08-10 2006-08-08 Xanthine derivatives as selective hm74a agonists

Country Status (4)

Country Link
CN (2) CN101282976A (ru)
GB (1) GB0516464D0 (ru)
UA (1) UA95780C2 (ru)
ZA (1) ZA200800778B (ru)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL2370440T3 (pl) * 2008-12-08 2015-05-29 Glaxosmithkline Llc Bezwodnik 2-amino-2-(hydroksymetylo)-1,3-propanodiolu 8-chloru-3-pentylo-3,7-dihydro-1H-puryno-2,6-dionu do leczenia chorób
AP2013006678A0 (en) * 2010-08-16 2013-01-31 Boehringer Ingelheim Int Oxadiazole inhibitors of leukotriene production
CN102276610B (zh) * 2011-05-04 2013-01-09 北京工业大学 N7-鸟嘌呤烷化物的制备方法
WO2018162607A1 (en) * 2017-03-07 2018-09-13 F. Hoffmann-La Roche Ag Oxadiazole transient receptor potential channel inhibitors
US20220380370A1 (en) * 2019-09-25 2022-12-01 Goldfinch Bio, Inc. Xanthine cb1 inhibitors

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003004496A1 (en) * 2001-07-03 2003-01-16 Novo Nordisk A/S Dpp-iv-inhibiting purine derivatives for the treatment of diabetes
GB0319124D0 (en) * 2003-08-14 2003-09-17 Smithkline Beecham Corp Chemical compounds

Also Published As

Publication number Publication date
CN101282976A (zh) 2008-10-08
ZA200800778B (en) 2008-11-26
GB0516464D0 (en) 2005-09-14
CN101282977B (zh) 2011-07-27
CN101282977A (zh) 2008-10-08

Similar Documents

Publication Publication Date Title
MY142067A (en) Xanthine derivatives as selective hm74a agonists, processes for the manufacture of said derivatives, formulations comprising these derivatives, and their use in the treatment of diseases where under-activation of the hm74a receptor contributes to the disease
MX2007004882A (es) Derivados de xantina con actividad de receptor de hm74a.
HRP20130406T1 (hr) Medikamenti s aktivnošä†u prema receptoru hm74a
TW200606162A (en) Pyrazolopyridine derivatives
TW200728305A (en) Spiropiperidine beta-sectetase inhibitors for the treatment of alzheimer's disease
MX2007008924A (es) Compuestos quimicos.
GEP20125565B (en) Lactam compounds and their pharmaceutical use
TW200634003A (en) Chemical compounds
TW200616974A (en) Chemical compounds
EP1841426A4 (en) TERTIARY CARBINAMINES INCLUDING SUBSTITUTED HETEROCYCLES AS BETA SECRETASE INHIBITORS AND FOR THE TREATMENT OF ALZHEIMER'S DISEASE
TW200621259A (en) Chemical compounds
TW200611695A (en) Pyrrolopyridine derivatives
UA104988C2 (ru) Производные пирониндола и способ их получения
EP1817312A4 (en) MACROCYCLIC AMINIOPYRIDYL BETA SEKRETASE INHIBITORS FOR THE TREATMENT OF MORBUS ALZHEIMER
MY138708A (en) Biaryloxymethylarenecarboxylic acids
EP2091328A4 (en) SPIROPIPERIDININHIBITORS OF BETA-SECRETASE FOR THE TREATMENT OF ALZHEIMER DISEASE
WO2005016867A3 (en) Anthranilic acid derivatives and their use as activators of the hm74a receptor
MY147677A (en) Piperazinyl derivatives useful in the treatment of gpr38 receptor mediated diseases
MX2008001211A (es) Derivados de bencilpiperazina y su uso medico.
SI1727817T1 (sl) Azabiciklooktan-3-onski derivati in njihova uporaba
UA86399C2 (ru) Применение 2,5 дигидроксибензолсульфоновой кислоты для изготовления лекарства, которые применяют для лечения болезней, зависимых от ангиогенеза
UA95780C2 (en) Xanthine derivatives as selective hm74a agonists
TW200738611A (en) 9-Chloro-15-deoxyprostaglandin derivatives, process for their preparation and their use as medicaments
EP2073635A4 (en) MACROCYCLIC SPIROPIPERIDINE BETA SEKRETASE INHIBITORS FOR THE TREATMENT OF MORBUS ALZHEIMER
TW200734335A (en) Compounds