UA95780C2 - Xanthine derivatives as selective hm74a agonists - Google Patents

Xanthine derivatives as selective hm74a agonists

Info

Publication number
UA95780C2
UA95780C2 UAA200801702A UAA200801702A UA95780C2 UA 95780 C2 UA95780 C2 UA 95780C2 UA A200801702 A UAA200801702 A UA A200801702A UA A200801702 A UAA200801702 A UA A200801702A UA 95780 C2 UA95780 C2 UA 95780C2
Authority
UA
Ukraine
Prior art keywords
xanthine derivatives
compounds
hm74a agonists
selective
derivatives
Prior art date
Application number
UAA200801702A
Other languages
Russian (ru)
Ukrainian (uk)
Inventor
Ричард Джонатан Дениэл Хетли
Эндрю МкМертри Мейсон
Иван Лео Пинто
Original Assignee
Глаксосмитклайн Ллс
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Глаксосмитклайн Ллс filed Critical Глаксосмитклайн Ллс
Publication of UA95780C2 publication Critical patent/UA95780C2/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
    • C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms

Abstract

The present invention relates to compounds 1 of formula (I) which are xanthine derivatives, processes for the manufacture of said derivatives, pharmaceutical formulations containing these, compounds and the use of the compounds in therapy, for example, in the treatment of diseases where under-activation of the HM74A receptor contributes to the disease or where activation of the receptor will be beneficial.
UAA200801702A 2005-08-10 2006-08-08 Xanthine derivatives as selective hm74a agonists UA95780C2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB0516464A GB0516464D0 (en) 2005-08-10 2005-08-10 Novel compounds

Publications (1)

Publication Number Publication Date
UA95780C2 true UA95780C2 (en) 2011-09-12

Family

ID=34984414

Family Applications (1)

Application Number Title Priority Date Filing Date
UAA200801702A UA95780C2 (en) 2005-08-10 2006-08-08 Xanthine derivatives as selective hm74a agonists

Country Status (4)

Country Link
CN (2) CN101282976A (en)
GB (1) GB0516464D0 (en)
UA (1) UA95780C2 (en)
ZA (1) ZA200800778B (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2009324811B2 (en) * 2008-12-08 2013-01-24 Glaxosmithkline Llc Novel compounds
EP2606045B1 (en) * 2010-08-16 2016-01-06 Boehringer Ingelheim International GmbH Oxadiazole inhibitors of leukotriene production
CN102276610B (en) * 2011-05-04 2013-01-09 北京工业大学 Method for preparing N7-guanine alkylate
JP7178357B2 (en) * 2017-03-07 2022-11-25 エフ．ホフマン－ラ ロシュ アーゲー Oxadiazole transient receptor potential channel inhibitor
JP2022549807A (en) * 2019-09-25 2022-11-29 ゴールドフィンチ バイオ，インク． Xanthine CB1 inhibitor

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1404675B1 (en) * 2001-07-03 2008-03-12 Novo Nordisk A/S Dpp-iv-inhibiting purine derivatives for the treatment of diabetes
GB0319124D0 (en) * 2003-08-14 2003-09-17 Smithkline Beecham Corp Chemical compounds

Also Published As

Publication number Publication date
CN101282977B (en) 2011-07-27
ZA200800778B (en) 2008-11-26
CN101282977A (en) 2008-10-08
CN101282976A (en) 2008-10-08
GB0516464D0 (en) 2005-09-14

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