UA95583C2 - Composition for treatment of displastic processes of uterine cervix - Google Patents

Composition for treatment of displastic processes of uterine cervix

Info

Publication number
UA95583C2
UA95583C2 UAA201011132A UAA201011132A UA95583C2 UA 95583 C2 UA95583 C2 UA 95583C2 UA A201011132 A UAA201011132 A UA A201011132A UA A201011132 A UAA201011132 A UA A201011132A UA 95583 C2 UA95583 C2 UA 95583C2
Authority
UA
Ukraine
Prior art keywords
uterine cervix
displastic
processes
treatment
composition
Prior art date
Application number
UAA201011132A
Other languages
Russian (ru)
Ukrainian (uk)
Inventor
Всеволод Иванович Киселев
Original Assignee
Общество С Ограниченной Ответственностью "Нанофарма
"Киселев Всеволод Иванович
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Общество С Ограниченной Ответственностью "Нанофарма, "Киселев Всеволод Иванович filed Critical Общество С Ограниченной Ответственностью "Нанофарма
Publication of UA95583C2 publication Critical patent/UA95583C2/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/02—Suppositories; Bougies; Bases therefor; Ovules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Reproductive Health (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Urology & Nephrology (AREA)
  • Inorganic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

The invention relates to medicine and the pharmaceutical industry, in particular to new agents for treating dysplastic changes in the uterine cervix and the rectal mucosa. The inventive medicinal agent for treating dysplastic changes in the uterine cervix and the rectal mucosa is in the form of a suppository and is characterized in that it contains 3,3'-diindolylmethane, epigallocatechin-3-gallate, a catalyst of the inhibitory activity of epigallocatechin-3-gallate with respect to DNA methyltransferase, consisting of Mgcations in the form of a pharmaceutically acceptable magnesium salt, a lipophilic base containing solid fat, polyvinylpyrrolidone and butylhydroxyanisole and/or butylhydroxytoluene. The agent is effective against severe dysplastic diseases.
UAA201011132A 2008-09-04 2009-08-18 Composition for treatment of displastic processes of uterine cervix UA95583C2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
RU2008135764/15A RU2395281C2 (en) 2008-09-04 2008-09-04 Pharmaceutical composition for treatment of dysplastic processes of cervix

Publications (1)

Publication Number Publication Date
UA95583C2 true UA95583C2 (en) 2011-08-10

Family

ID=41797309

Family Applications (1)

Application Number Title Priority Date Filing Date
UAA201011132A UA95583C2 (en) 2008-09-04 2009-08-18 Composition for treatment of displastic processes of uterine cervix

Country Status (4)

Country Link
EA (1) EA018383B1 (en)
RU (1) RU2395281C2 (en)
UA (1) UA95583C2 (en)
WO (1) WO2010027294A1 (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2454232C2 (en) * 2010-09-16 2012-06-27 Федеральное государственное бюджетное учреждение "Российский онкологический научный центр имени Н.Н. Блохина" Российской академии медицинских наук (ФГБУ "РОНЦ им. Н.Н. Блохина" РАМН) Application of triindolyl methane derivatives as anticancer drugs
RU2456987C1 (en) * 2011-03-21 2012-07-27 Сергей Владимирович Енгашев Method for producing gelatine capsules of 3,31-diindolylmethane
GB2533381A (en) * 2014-12-18 2016-06-22 Nordic Labs Ltd Novel treatment of STIs
RU2601621C2 (en) * 2015-03-18 2016-11-10 Общество с ограниченной ответственностью "Фармацевтический завод иммунных лекарственных средств" Sodium deoxyribonucleate suppositories, rectal and vaginal
GB2542106A (en) * 2015-04-01 2017-03-15 Nordic Labs Ltd Novel treatment of STIs
RU2601893C1 (en) * 2015-11-30 2016-11-10 Всеволод Иванович Киселев Drug preparation based on indole-3-carbinol with increased epigenetic activity
US20200179337A1 (en) * 2016-05-16 2020-06-11 Aktsionernoe Obschestvo "Veles Farma" Means for treating sexually transmitted infections
CN108969602A (en) * 2018-09-29 2018-12-11 南京依美生物科技有限公司 It is a kind of to treat the Chinese medicine composition and preparation method that human papilloma virus sun is turned out cloudy

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1275905B1 (en) * 1995-03-14 1997-10-24 Indena Spa POLYPHENOLIC FRACTIONS OF TEA, THEIR USE AND FORMULATIONS THAT CONTAIN THEM
RU2196568C1 (en) * 2001-08-08 2003-01-20 Киселев Всеволод Иванович Pharmaceutical composition for prophylaxis and treatment of uterus cervix dysplasia and cancer and larynx papillomatosis and method of prophylaxis and treatment of said sicknesses based on thereof
RU2301666C2 (en) * 2002-01-11 2007-06-27 Маттиас Рат Polyphenol-base pharmaceutical composition possessing nutrient properties and its using in cancer treatment
RU2318510C1 (en) * 2006-04-19 2008-03-10 Всеволод Иванович Киселев 3,3'-diindolylmethane (metindol)-base vaginal suppository
RU2315594C1 (en) * 2006-09-01 2008-01-27 Всеволод Иванович Киселев Anti-estrogenic and anti-proliferative agent for treatment and prophylaxis of female reproductive system diseases

Also Published As

Publication number Publication date
WO2010027294A1 (en) 2010-03-11
EA201100417A1 (en) 2011-10-31
RU2395281C2 (en) 2010-07-27
EA018383B1 (en) 2013-07-30
RU2008135764A (en) 2010-03-10

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