UA89630C2 - Схема комбинированного дозирования для эритропоэтина - Google Patents

Схема комбинированного дозирования для эритропоэтина

Info

Publication number
UA89630C2
UA89630C2 UAA200610352A UAA200610352A UA89630C2 UA 89630 C2 UA89630 C2 UA 89630C2 UA A200610352 A UAA200610352 A UA A200610352A UA A200610352 A UAA200610352 A UA A200610352A UA 89630 C2 UA89630 C2 UA 89630C2
Authority
UA
Ukraine
Prior art keywords
dosing regimen
erythropoietin
epo
combination dosing
reticulocytes
Prior art date
Application number
UAA200610352A
Other languages
English (en)
Ukrainian (uk)
Inventor
Винг К. Чунг
Original Assignee
Янссен Фармацевтика Н.В.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Янссен Фармацевтика Н.В. filed Critical Янссен Фармацевтика Н.В.
Publication of UA89630C2 publication Critical patent/UA89630C2/ru

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18Growth factors; Growth regulators
    • A61K38/1816Erythropoietin [EPO]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06Antianaemics

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Endocrinology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)

Abstract

Изобретение касается применения эритропоэтина (ЭПО) для лечения состояний, которые нуждаются в повышении общего количества эритроцитов и концентрации гемоглобина у пациентов, которые нуждаются в таком лечении, путем введения указанному субъекту соответственно схеме комбинированного дозирования двух экспозиций терапевтически эффективного количества ЭПО, которое отличается тем, что первую экспозицию вводят в виде одиночной дозы в диапазоне приблизительно от 150 IU/кг приблизительно до 2400 IU/кг, а вторую экспозицию вводят в виде одиночной или множественных доз низкого уровня, не превышающих приблизительно 100 IU/кг/пор, и вторую экспозицию инициируют в пределах приблизительно от 3 до 10 суток после первой.
UAA200610352A 2004-03-26 2005-03-24 Схема комбинированного дозирования для эритропоэтина UA89630C2 (ru)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US55692304P 2004-03-26 2004-03-26

Publications (1)

Publication Number Publication Date
UA89630C2 true UA89630C2 (ru) 2010-02-25

Family

ID=34964370

Family Applications (1)

Application Number Title Priority Date Filing Date
UAA200610352A UA89630C2 (ru) 2004-03-26 2005-03-24 Схема комбинированного дозирования для эритропоэтина

Country Status (17)

Country Link
US (1) US20050267026A1 (ru)
EP (1) EP1737484A1 (ru)
JP (1) JP2007530578A (ru)
KR (1) KR20070015549A (ru)
CN (1) CN1960745A (ru)
AU (1) AU2005231307A1 (ru)
BR (1) BRPI0509239A (ru)
CA (1) CA2561222A1 (ru)
CR (1) CR8705A (ru)
EA (1) EA010889B1 (ru)
EC (1) ECSP066885A (ru)
IL (1) IL178288A0 (ru)
MX (1) MXPA06011084A (ru)
NO (1) NO20064908L (ru)
UA (1) UA89630C2 (ru)
WO (1) WO2005097167A1 (ru)
ZA (1) ZA200608877B (ru)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20150164991A1 (en) * 2013-11-01 2015-06-18 Vanderbilt University Method and Kit for Evaluating and Monitoring a Treatment Program for Anemia

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2248215C2 (ru) * 1999-05-11 2005-03-20 Орто-Макнейл Фармасьютикал, Инк. Фармакокинетическое и фармакодинамическое моделирование введения эритропоэтина
KR100693263B1 (ko) * 1999-07-22 2007-03-13 아벤티스 파마슈티칼스 인크. 다중 투여형 에리트로포이에틴 제형
EP1525889A1 (en) * 2000-05-15 2005-04-27 F. Hoffmann-La Roche Ag Liquid pharmaceutical composition containing an erythropoietin derivative
US7078376B1 (en) * 2000-08-11 2006-07-18 Baxter Healthcare S.A. Therapeutic methods for treating subjects with a recombinant erythropoietin having high activity and reduced side effects

Also Published As

Publication number Publication date
NO20064908L (no) 2006-12-15
BRPI0509239A (pt) 2007-09-04
JP2007530578A (ja) 2007-11-01
EA010889B1 (ru) 2008-12-30
US20050267026A1 (en) 2005-12-01
CA2561222A1 (en) 2005-10-20
CN1960745A (zh) 2007-05-09
WO2005097167A1 (en) 2005-10-20
MXPA06011084A (es) 2007-03-21
ZA200608877B (en) 2008-06-25
AU2005231307A1 (en) 2005-10-20
EA200601782A1 (ru) 2007-04-27
ECSP066885A (es) 2006-11-24
EP1737484A1 (en) 2007-01-03
IL178288A0 (en) 2006-12-31
KR20070015549A (ko) 2007-02-05
CR8705A (es) 2008-09-09

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