UA87158C2 - Тестостероновый гель, содержащий пропиленгликоль в качестве усилителя проникающей способности - Google Patents
Тестостероновый гель, содержащий пропиленгликоль в качестве усилителя проникающей способностиInfo
- Publication number
- UA87158C2 UA87158C2 UAA200703868A UAA200703868A UA87158C2 UA 87158 C2 UA87158 C2 UA 87158C2 UA A200703868 A UAA200703868 A UA A200703868A UA A200703868 A UAA200703868 A UA A200703868A UA 87158 C2 UA87158 C2 UA 87158C2
- Authority
- UA
- Ukraine
- Prior art keywords
- propylene glycol
- containing propylene
- penetration enhancer
- gels containing
- testosterone gels
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
- A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/38—Cellulose; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Inorganic Chemistry (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Organic Chemistry (AREA)
- Endocrinology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Reproductive Health (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Данное изобретение относится к тестостеронсодержащим фармацевтическим композициям в форме геля, содержащего пропиленгликоль, в качестве агента, повышающего проницаемость.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP04292170A EP1634583A1 (en) | 2004-09-09 | 2004-09-09 | Testosterone gels comprising propylene glycol as penetration enhancer |
Publications (1)
Publication Number | Publication Date |
---|---|
UA87158C2 true UA87158C2 (ru) | 2009-06-25 |
Family
ID=34931375
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
UAA200703868A UA87158C2 (ru) | 2004-09-09 | 2005-09-07 | Тестостероновый гель, содержащий пропиленгликоль в качестве усилителя проникающей способности |
Country Status (12)
Country | Link |
---|---|
US (1) | US20080038220A1 (ru) |
EP (3) | EP1634583A1 (ru) |
KR (1) | KR20070099532A (ru) |
CN (1) | CN101018542B (ru) |
AU (1) | AU2005281809A1 (ru) |
CA (1) | CA2578225C (ru) |
DK (1) | DK1786398T3 (ru) |
ES (1) | ES2548723T3 (ru) |
NO (1) | NO341780B1 (ru) |
UA (1) | UA87158C2 (ru) |
WO (1) | WO2006027278A1 (ru) |
ZA (1) | ZA200701864B (ru) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6503894B1 (en) | 2000-08-30 | 2003-01-07 | Unimed Pharmaceuticals, Inc. | Pharmaceutical composition and method for treating hypogonadism |
WO2004000263A1 (en) | 2002-06-25 | 2003-12-31 | Acrux Dds Pty Ltd | Transdermal delivery rate control using amorphous pharmaceutical compositions |
KR20080016552A (ko) * | 2005-04-13 | 2008-02-21 | 유니메드 파마슈티칼스, 인크. | 여성의 테스토스테론 및 관련된 스테로이드의 농도를증가시키는 방법 |
US8067399B2 (en) | 2005-05-27 | 2011-11-29 | Antares Pharma Ipl Ag | Method and apparatus for transdermal or transmucosal application of testosterone |
BRPI0611134A2 (pt) | 2005-06-03 | 2010-08-17 | Acrux Dds Pty Ltd | método e composição para liberação transdérmica de fármaco |
PT1937276E (pt) | 2005-10-12 | 2013-02-21 | Besins Healthcare Luxembourg | Gel de testosterona melhorado e método para a sua utilização |
CA2646667C (en) | 2006-04-21 | 2014-03-11 | Antares Pharma Ipl Ag | Methods of treating hot flashes with formulations for transdermal or transmucosal application |
EP2106272A4 (en) | 2007-01-11 | 2011-05-04 | Acrux Dds Pty Ltd | SPREIZUTENSIL |
US20090285893A1 (en) * | 2008-05-19 | 2009-11-19 | The Procter & Gamble Company | Treatment of heart failure in women |
EP2147674A1 (en) * | 2008-07-24 | 2010-01-27 | Besins Healthcare | Transdermal pharmaceutical compositions comprising danazol |
BRPI0921685A2 (pt) * | 2008-10-31 | 2016-02-16 | Moberg Derma Ab | composição tópica compreendendo uma combinação de pelo menos dois agentes que melhoram a penetração. |
PT2373305T (pt) * | 2008-12-11 | 2017-06-14 | Besins Healthcare Lu Sarl | Resumo |
WO2011046522A2 (fr) * | 2009-10-16 | 2011-04-21 | Rached Smida | Nouvelles applications de la testosterone libre reconstituee |
US10080760B2 (en) * | 2009-10-27 | 2018-09-25 | Besins Healthcare Luxembourg Sarl | Transdermal pharmaceutical compositions comprising active agents |
JO3755B1 (ar) * | 2011-01-26 | 2021-01-31 | Ferring Bv | تركيبات تستوستيرون |
USD749225S1 (en) | 2013-11-26 | 2016-02-09 | Acrux Dds Pty Ltd | Topical spreading applicator |
USD750788S1 (en) | 2013-11-26 | 2016-03-01 | Acrux Dds Pty Ltd | Topical spreading applicator |
US20160361321A1 (en) * | 2014-02-25 | 2016-12-15 | Intas Pharmaceuticals Limited | Stable transdermal testosterone gel |
Family Cites Families (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5238933A (en) * | 1991-10-28 | 1993-08-24 | Sri International | Skin permeation enhancer compositions |
US5837289A (en) * | 1996-07-23 | 1998-11-17 | Grasela; John C. | Transdermal delivery of medications using a combination of penetration enhancers |
US5760096A (en) * | 1996-10-18 | 1998-06-02 | Thornfeldt; Carl R. | Potent penetration enhancers |
US5968919A (en) * | 1997-10-16 | 1999-10-19 | Macrochem Corporation | Hormone replacement therapy drug formulations for topical application to the skin |
CN1172674C (zh) * | 1997-11-10 | 2004-10-27 | 赛勒吉药物股份有限公司 | 促进渗透和减少刺激的系统 |
US6582724B2 (en) * | 1999-12-16 | 2003-06-24 | Dermatrends, Inc. | Dual enhancer composition for topical and transdermal drug delivery |
US20040002482A1 (en) * | 2000-08-30 | 2004-01-01 | Dudley Robert E. | Androgen pharmaceutical composition and method for treating depression |
WO2002017927A1 (en) * | 2000-08-30 | 2002-03-07 | Unimed Pharmaceuticals, Inc. | Method for treating erectile dysfunction and increasing libido in men |
US20030139384A1 (en) * | 2000-08-30 | 2003-07-24 | Dudley Robert E. | Method for treating erectile dysfunction and increasing libido in men |
US6503894B1 (en) * | 2000-08-30 | 2003-01-07 | Unimed Pharmaceuticals, Inc. | Pharmaceutical composition and method for treating hypogonadism |
US20040092494A9 (en) * | 2000-08-30 | 2004-05-13 | Dudley Robert E. | Method of increasing testosterone and related steroid concentrations in women |
DE20121209U1 (de) * | 2000-12-22 | 2002-06-20 | August Wolff Gmbh & Co Arzneim | Gelzusammensetzung zur Behandlung von Hypogonadismus |
US20040072810A1 (en) * | 2001-11-07 | 2004-04-15 | Besins International Belgique | Pharmaceutical composition in the form of a gel or a solution based on dihydrotestosterone, process for preparing it and uses thereof |
PT1317921E (pt) * | 2001-12-07 | 2009-11-06 | Besins Mfg Belgium | Composição farmacêutica sob a forma de gel ou de solução à base de di-hidrotestosterona, seu processo de preparação e suas utilizações |
MY139721A (en) * | 2002-04-19 | 2009-10-30 | Cpex Pharmaceuticals Inc | Pharmaceutical composition |
US20050020552A1 (en) * | 2003-07-16 | 2005-01-27 | Chaim Aschkenasy | Pharmaceutical composition and method for transdermal drug delivery |
PT1937276E (pt) * | 2005-10-12 | 2013-02-21 | Besins Healthcare Luxembourg | Gel de testosterona melhorado e método para a sua utilização |
-
2004
- 2004-09-09 EP EP04292170A patent/EP1634583A1/en not_active Withdrawn
-
2005
- 2005-09-07 WO PCT/EP2005/010293 patent/WO2006027278A1/en active Application Filing
- 2005-09-07 ES ES05794868.9T patent/ES2548723T3/es active Active
- 2005-09-07 US US11/662,339 patent/US20080038220A1/en not_active Abandoned
- 2005-09-07 ZA ZA200701864A patent/ZA200701864B/en unknown
- 2005-09-07 CA CA2578225A patent/CA2578225C/en active Active
- 2005-09-07 UA UAA200703868A patent/UA87158C2/ru unknown
- 2005-09-07 DK DK05794868.9T patent/DK1786398T3/en active
- 2005-09-07 EP EP05794868.9A patent/EP1786398B1/en active Active
- 2005-09-07 CN CN200580030119.2A patent/CN101018542B/zh active Active
- 2005-09-07 AU AU2005281809A patent/AU2005281809A1/en not_active Abandoned
- 2005-09-07 KR KR1020077007927A patent/KR20070099532A/ko not_active Application Discontinuation
- 2005-09-07 EP EP15179563.0A patent/EP2957279B1/en active Active
-
2007
- 2007-04-10 NO NO20071823A patent/NO341780B1/no unknown
Also Published As
Publication number | Publication date |
---|---|
ZA200701864B (en) | 2008-05-28 |
AU2005281809A1 (en) | 2006-03-16 |
EP1786398A1 (en) | 2007-05-23 |
CN101018542B (zh) | 2020-05-19 |
DK1786398T3 (en) | 2015-11-23 |
NO20071823L (no) | 2007-06-11 |
EP2957279B1 (en) | 2022-11-02 |
KR20070099532A (ko) | 2007-10-09 |
CA2578225A1 (en) | 2006-03-16 |
CN101018542A (zh) | 2007-08-15 |
CA2578225C (en) | 2014-06-03 |
EP2957279A1 (en) | 2015-12-23 |
NO341780B1 (no) | 2018-01-22 |
ES2548723T3 (es) | 2015-10-20 |
EP1786398B1 (en) | 2015-08-12 |
WO2006027278A1 (en) | 2006-03-16 |
EP1634583A1 (en) | 2006-03-15 |
US20080038220A1 (en) | 2008-02-14 |
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